Summary: An autonomous region located in central Asia, within China.

Top Publications

  1. Hinsenkamp M, Mathieu F, Claus W, Collard J, de Maertelaer V. Effects of physical environment on the evolution of Kashin-Beck disease in Tibet. Int Orthop. 2009;33:1085-8 pubmed publisher
    ..001). In the group with history of frostbite, 58% present the severest stages vs. 40% without (p < 0.001). The results confirm a highly significant relation between microtrauma and cold and the severity of the KBD alterations. ..
  2. Wang Y, Xu N, Xi A, Ahmed Z, Zhang B, Bai X. Effects of Lactobacillus plantarum MA2 isolated from Tibet kefir on lipid metabolism and intestinal microflora of rats fed on high-cholesterol diet. Appl Microbiol Biotechnol. 2009;84:341-7 pubmed publisher
    ..of this study was to evaluate the effects of Lactobacillus plantarum MA2, an isolate from Chinese traditional Tibet kefir, on cholesterol-lowering and microflora of rat in vivo...
  3. Budke C, Campos Ponce M, Qian W, Torgerson P. A canine purgation study and risk factor analysis for echinococcosis in a high endemic region of the Tibetan plateau. Vet Parasitol. 2005;127:43-49 pubmed
    ..Male dogs were more likely to be infected with Echinococcus spp. than female dogs (P<0.05) and dogs allowed to roam were more likely to be infected with E. multilocularis (P<0.05). ..
  4. Singh S. Tears from the land of snow: health and human rights in Tibet. Lancet. 2004;364:1009 pubmed
  5. Dunzhu S, Wang F, Courtright P, Liu L, Tenzing C, Noertjojo K, et al. Blindness and eye diseases in Tibet: findings from a randomised, population based survey. Br J Ophthalmol. 2003;87:1443-8 pubmed
    Public health officials of the Tibet Autonomous Region (TAR) of China requested a survey of blindness, eye diseases, and eye care service utilisation to assist the development of a 10 year blindness prevention and treatment plan...
  6. Lau C, Aitchison J, Pointing S. Early colonization of thermal niches in a silica-depositing hot spring in central Tibet. Geobiology. 2008;6:136-46 pubmed publisher
    ..castenholzii commonly develop around sinter-depositing geysers in the Daggyai Tso geothermal field of central Tibet. In this study we used morphological and molecular genetic techniques to reveal a diverse pioneer biofilm ..
  7. Le P, Jones Le E, Bell C, Miller S. Preferences for perinatal health communication of women in rural Tibet. J Obstet Gynecol Neonatal Nurs. 2009;38:108-17 pubmed publisher
    To describe the most acceptable methods for educating women in Medrogongkar County, Tibet, about healthy pregnancy and safe motherhood...
  8. Qi Y, Niu W, Zhu T, Zhou W, Qiu C. Synergistic effect of the genetic polymorphisms of the renin-angiotensin-aldosterone system on high-altitude pulmonary edema: a study from Qinghai-Tibet altitude. Eur J Epidemiol. 2008;23:143-52 pubmed
    ..We recruited 140 HAPE patients and 144 controls during the construction of Qinghai-Tibet railway and genotyped 10 gene polymorphisms evenly interspersed in 5 RAAS candidate genes...
  9. Adams V, Miller S, Chertow J, Craig S, Samen A, Varner M. Having a "safe delivery": conflicting views from Tibet. Health Care Women Int. 2005;26:821-51 pubmed
    ..Tibetan medical theory, practice, and pharmacology include information on maternal and child health care, Tibet is one of the few societies in the world that does not have traditional birth attendants or midwives...

Scientific Experts

More Information


  1. Dang S, Yan H, Yamamoto S. High altitude and early childhood growth retardation: new evidence from Tibet. Eur J Clin Nutr. 2008;62:342-8 pubmed
    To assess possible effect of high altitude on early childhood growth in Tibet. A cross-sectional survey on child health and nutrition was conducted in Tibet with stratified multistage cluster random sampling technique...
  2. Ji T, Liu C, Wang A, Yang J, Su Y, Yuan L, et al. [Studies on the chemical constituents of Urtica dioica L. grown in Tibet Autonomous Region]. Zhong Yao Cai. 2007;30:662-4 pubmed
    Studies on the whole herb of Urtica dioica L. grown in Nyingchi area, China's Tibet Autonomous Region, resulted in the isolated of nine compounds: beta-sitosterol, trans-ferulic acid, dotriacotane, erucic acid, ursolic acid, scopoletin, ..
  3. Qiu J. China: The third pole. Nature. 2008;454:393-6 pubmed publisher
  4. Droma Y, Kunii O, Yangzom Y, Shan M, Pingzo L, Song P. Prevalence and severity of asthma and allergies in schoolchildren in Lhasa, Tibet. Clin Exp Allergy. 2007;37:1326-33 pubmed
    ..The prevalence of asthma, allergic rhinoconjunctivitis and eczema over the past 12 months was the lowest among the centres, that performed ISAAC worldwide. ..
  5. Kan F, Chen Z, Wang E, Tian C, Sui X, Chen W. Characterization of symbiotic and endophytic bacteria isolated from root nodules of herbaceous legumes grown in Qinghai-Tibet plateau and in other zones of China. Arch Microbiol. 2007;188:103-15 pubmed
    Qinghai-Tibet plateau is the highest place in the world and the environment in that plateau is hard for animals and plants, with low temperature, low concentration of oxygen and high solar radiation...
  6. Wang Q, Qiu J, Yang W, Schantz P, Raoul F, Craig P, et al. Socioeconomic and behavior risk factors of human alveolar echinococcosis in Tibetan communities in Sichuan, People's Republic of China. Am J Trop Med Hyg. 2006;74:856-62 pubmed
  7. Zhu B, Liu S, Ci D, Huang J, Wang Y, Chen L, et al. Population genetics for Y-chromosomal STRs haplotypes of Chinese Tibetan ethnic minority group in Tibet. Forensic Sci Int. 2006;161:78-83 pubmed
    ..9981, and the discrimination capacity was 0.9897. The results in the present study can be used for routine forensic application in the region, and enrich Chinese ethnical genetic informational resources. ..
  8. Lau M, Aitchison J, Pointing S. Bacterial community composition in thermophilic microbial mats from five hot springs in central Tibet. Extremophiles. 2009;13:139-49 pubmed publisher
    ..A sequence-based survey of bacterial communities from several hot spring locations in central Tibet was undertaken...
  9. Miller S, Tudor C, Thorsten V, Wright L, Varner M. Comparison of maternal and newborn outcomes of Tibetan and Han Chinese delivering in Lhasa, Tibet. J Obstet Gynaecol Res. 2008;34:986-93 pubmed publisher
    ..neonatal outcomes of Tibetan and Han Chinese women delivering vaginally at high altitude (3650 meters) in Lhasa, Tibet Autonomous Region, People's Republic of China...
  10. Kang L, Li S. Allele frequencies of 15 STR loci of Luoba ethnic group in Tibet (Southwestern China). Forensic Sci Int. 2005;155:219-21 pubmed
    ..Identifiler kit were obtained from a sample of 93 healthy unrelated individuals of Luoba population born in Tibet Autonomy Region of China (Southwestern China)...
  11. Kang L, Zhao J, Liu K, Li X. Allele frequencies of 15 STR loci of Tibetan lived in Tibet Lassa. Forensic Sci Int. 2007;168:236-40 pubmed
    ..STR Identifiler kit were obtained from a sample of 196 healthy unrelated individuals of Tibetan born in Lassa of Tibet Autonomy Region of China (SW China)...
  12. Budke C, Jiamin Q, Zinsstag J, Qian W, Torgerson P. Use of disability adjusted life years in the estimation of the disease burden of echinococcosis for a high endemic region of the Tibetan plateau. Am J Trop Med Hyg. 2004;71:56-64 pubmed
    ..This study has clearly shown that the impact of DALYs lost due to echinococcosis, in terms of medical treatment costs, lost income, and physical and social suffering, is likely to be substantial in this highly endemic region of China. ..
  13. Wen B, Xie X, Gao S, Li H, Shi H, Song X, et al. Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans. Am J Hum Genet. 2004;74:856-65 pubmed
    ..This is the first genetic evidence revealing sex-biased admixture in STB populations, which has genetic, historical, and anthropological implications. ..
  14. Wang Z, Bao J, Wu X, Liu Y, Li L, Liu C, et al. Peste des petits ruminants virus in Tibet, China. Emerg Infect Dis. 2009;15:299-301 pubmed
    ..des petits ruminants virus (PPRV) infection has emerged in goats and sheep in the Ngari region of southwestern Tibet, People's Republic of China...
  15. Wu S, Pan J, Wang X, Zhou S, Zhang G, Liu Q, et al. Anopheles pseudowillmori is the predominant malaria vector in Motuo County, Tibet Autonomous Region. Malar J. 2009;8:46 pubmed publisher
    Malaria is endemic in Linzhi Prefecture in the Tibet Autonomous Region (TAR), but the vector for malaria transmission had never been identified. Adult Anopheles spp...
  16. Wang A, Yu Z, Ding Y. Genetic diversity analysis of wild close relatives of barley from Tibet and the Middle East by ISSR and SSR markers. C R Biol. 2009;332:393-403 pubmed publisher
    The genetic diversity analysis of 90 barley samples, including 45 wild close relatives of barley from the Tibet region of China and 45 wild accessions from different countries throughout the Middle East, were carried out using ISSR and ..
  17. Cao G, Xu X, Long R, Wang Q, Wang C, Du Y, et al. Methane emissions by alpine plant communities in the Qinghai-Tibet Plateau. Biol Lett. 2008;4:681-4 pubmed publisher
    ..time to our knowledge, we report here methane emissions by plant communities in alpine ecosystems in the Qinghai-Tibet Plateau...
  18. Wang Y, Ahmed Z, Feng W, Li C, Song S. Physicochemical properties of exopolysaccharide produced by Lactobacillus kefiranofaciens ZW3 isolated from Tibet kefir. Int J Biol Macromol. 2008;43:283-8 pubmed publisher
    An exopolysaccharide (EPS) producing strain, ZW3, was isolated from Tibet kefir grain and was identified as Lactobacillus kefiranofaciens...
  19. Kang L, Yuan D, Yang F, Liu K, Za X. Genetic polymorphisms of 15 STR loci in two Tibetan populations from Tibet Changdu and Naqu, China. Forensic Sci Int. 2007;169:239-43 pubmed
    ..STR Identifiler kit was examined in 100 Changdu Tibetan and 118 Naqu Tibetan unrelated individuals living in the Tibet Province, PR China...
  20. Bao J, Li L, Wang Z, Barrett T, Suo L, Zhao W, et al. Development of one-step real-time RT-PCR assay for detection and quantitation of peste des petits ruminants virus. J Virol Methods. 2008;148:232-6 pubmed publisher
    ..7% to 73.3% by use of the real-time qRT-PCR. The real-time qRT-PCR assay described in this report allows the rapid, specific and sensitive laboratory detection of PPRV in tissue samples from field cases...
  21. Ming M, Lu M, Balashov S, Ebrey T, Li Q, Ding J. pH dependence of light-driven proton pumping by an archaerhodopsin from Tibet: comparison with bacteriorhodopsin. Biophys J. 2006;90:3322-32 pubmed
    ..We found also that all pK(a)s of the key amino acid residues in AR4 were elevated compared to those of BR. ..
  22. Zhang Z, Zhou H, Zhao X, Chang F, Wang H, Li X, et al. [Epidemiological survey on malaria situation in Motuo County of Tibet, China]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2008;26:343-8 pubmed
    To make an epidemiological investigation on malaria in Motuo County, Linzhi Prefecture of Tibet. In July of the year 2006, the following activities were conducted in 2 selected villages from each of the three townships, i.e...
  23. Kang L, Li S. X-chromosome STR polymorphism of Luoba Ethnic Group living in Tibet (SW China). Forensic Sci Int. 2006;156:88-90 pubmed
    ..X-chromosome STR loci, namely DXS7133, DXS6789, DXS6804, DXS6799, DXS8378, DXS101, DXS7424, DXS7132, DXS7423 and HPRTB were determined from healthy unrelated males and female individuals of Luoba Ethnic Group living in Tibet (SW China).
  24. Li H, Gao R, Wu M, Wang L, Fu M, Wu K. Molecular cloning and expression of IL2 cDNA from the Tibet pig. Vet Res Commun. 2005;29:395-405 pubmed
    ..In our experiment, IL2 cDNA of the Tibet Pig was first cloned by RT-PCR from ConA-stimulated lymphocytes in the blood and subcloned into pMD-18 T vector, ..
  25. Bassett K, Noertjojo K, Liu L, Wang F, Tenzing C, Wilkie A, et al. Cataract surgical coverage and outcome in the Tibet Autonomous Region of China. Br J Ophthalmol. 2005;89:5-9 pubmed
    A recently published, population based survey of the Tibet Autonomous Region (TAR) of China reported on low vision, blindness, and blinding conditions...
  26. Fan H, Xue Y, Ma Y, Ventosa A, Grant W. Halorubrum tibetense sp. nov., a novel haloalkaliphilic archaeon from Lake Zabuye in Tibet, China. Int J Syst Evol Microbiol. 2004;54:1213-6 pubmed
    ..Therefore, strain 8W8T represents a novel species, for which the name Halorubrum tibetense sp. nov. is proposed, with the type strain 8W8T (=AS 1.3239T=JCM 11889T). ..
  27. Inokuma H, Beppu T, Okuda M, Shimada Y, Sakata Y. Detection of ehrlichial DNA in Haemaphysalis ticks recovered from dogs in Japan that is closely related to a novel Ehrlichia sp. found in cattle ticks from Tibet, Thailand, and Africa. J Clin Microbiol. 2004;42:1353-5 pubmed
    ..Three positive samples were detected from Haemaphysalis ticks, and higher levels of similarity (98.46 to 99.06%) were found to recently detected Ehrlichia spp. from cattle ticks in Tibet, Thailand, and Africa.
  28. Wu H, Geng P. [Research on Tibetan drugs: current status and prospects]. Zhong Yao Cai. 2002;25:65-6 pubmed
  29. Miller S, Tudor C, Thorsten V, Nyima -, Kalyang -, Sonam -, et al. Randomized double masked trial of Zhi Byed 11, a Tibetan traditional medicine, versus misoprostol to prevent postpartum hemorrhage in Lhasa, Tibet. J Midwifery Womens Health. 2009;54:133-141.e1 pubmed publisher
    ..We conducted a double-blind randomized controlled trial at three hospitals in Lhasa, Tibet, People's Republic of China. Women (N = 967) were randomized to either ZB11 or misoprostol groups...
  30. Adams V. Saving Tibet? An inquiry into modernity, lies, truths, and beliefs. Med Anthropol. 2005;24:71-110 pubmed
    ..quot; An exploration of the effects of attempts to quantify maternal behavior, morbidity, and morality in rural Tibet highlights the problem of morality within an environment in which numbers are never free-standing but, rather, are ..
  31. Wu T, Wang X, Wei C, Cheng H, Wang X, Li Y, et al. Hemoglobin levels in Qinghai-Tibet: different effects of gender for Tibetans vs. Han. J Appl Physiol (1985). 2005;98:598-604 pubmed
    ..We suggest that the Han-Tibetan ethnic difference in the effect of altitude on hemoglobin concentration depends to a large extent on gender. ..
  32. Gao X, Yu Q, Gu Q, Chen Y, Ding K, Zhu J, et al. Indoor air pollution from solid biomass fuels combustion in rural agricultural area of Tibet, China. Indoor Air. 2009;19:198-205 pubmed publisher
    ..the indoor air pollution and to estimate the residents' pollution exposure reduction of energy altering in rural Tibet. Daily PM(2...
  33. Xiao N, Qiu J, Nakao M, Nakaya K, Yamasaki H, Sako Y, et al. Short report: Identification of Echinococcus species from a yak in the Qinghai-Tibet plateau region of China. Am J Trop Med Hyg. 2003;69:445-6 pubmed
    The species identification of an echinococcal lesion in the liver of a yak in the Qinghai-Tibet plateau region of China, where both Echinococcus granulosus and E...
  34. Rise P, Marangoni F, Martiello A, Colombo C, Manzoni C, Marconi C, et al. Fatty acid profiles of blood lipids in a population group in Tibet: correlations with diet and environmental conditions. Asia Pac J Clin Nutr. 2008;17:80-5 pubmed
    ..and environmental factors, such as dietary fats and altitudes of Milan, Italy (a low altitude site), and Lhasa, Tibet (a high altitude site) appear to contribute to these differences...
  35. Qi D, Li T, Zhao X, Guo S, Li J. Mitochondrial cytochrome b sequence variation and phylogenetics of the highly specialized Schizothoracine fishes (Teleostei: Cyprinidae) in the Qinghai-Tibet plateau. Biochem Genet. 2006;44:270-85 pubmed
    ..five species of all four genera of highly specialized schizothoracine fishes distributed in the Qinghai-Tibet plateau...
  36. Miller S, Le P, Craig S, Adams V, Tudor C, Sonam -, et al. How to make consent informed: possible lessons from Tibet. IRB. 2007;29:7-14 pubmed
  37. Zhao Y, Zhang Q, Tsering T, Sangwan -, Hu X, Liu L, et al. Prevalence of convulsive epilepsy and health-related quality of life of the population with convulsive epilepsy in rural areas of Tibet Autonomous Region in China: an initial survey. Epilepsy Behav. 2008;12:373-81 pubmed publisher
    ..study was to establish the prevalence rate of convulsive epilepsy and the treatment gap in some rural areas of Tibet Autonomous Region in China, to evaluate the quality of life (QOL) of patients with epilepsy and identify factors ..
  38. Mi J, Lin L, Ma G, Gu X, Liu M, Cheng H, et al. [Prevalence of vitamin A deficiency in children under six years of age in Tibet, China]. Zhonghua Yu Fang Yi Xue Za Zhi. 2003;37:419-22 pubmed
    To understand the prevalence of vitamin A deficiency (VAD) among children under six years of age in Tibet, China...
  39. Wu T, Ding S, Liu J, Yu M, Jia J, Chai Z, et al. Who should not go high: chronic disease and work at altitude during construction of the Qinghai-Tibet railroad. High Alt Med Biol. 2007;8:88-107 pubmed
  40. Yangzom Y, Qian L, Shan M, La Y, Meiduo D, Hu X, et al. Outcome of hospital deliveries of women living at high altitude: a study from Lhasa in Tibet. Acta Paediatr. 2008;97:317-21 pubmed publisher
    ..prospectively collected on the outcome of all liveborn infants born in four hospitals in the urban area of Lhasa, Tibet, in 2005. A total of 2540 liveborn infants were recorded. The rates of LBW, preterm birth and SGA were 13.6%, 5...
  41. Xiao N, Qiu J, Nakao M, Li T, Yang W, Chen X, et al. Echinococcus shiquicus, a new species from the Qinghai-Tibet plateau region of China: discovery and epidemiological implications. Parasitol Int. 2006;55 Suppl:S233-6 pubmed
    In Shiqu County of the Qinghai-Tibet plateau, many wild and domestic mammals are involved in the transmission cycles of Echinococcus spp...
  42. Liu J, Wang L, Geng Y, Wang Q, Luo L, Zhong Y. Genetic diversity and population structure of Lamiophlomis rotata (Lamiaceae), an endemic species of Qinghai-Tibet Plateau. Genetica. 2006;128:385-94 pubmed
    Lamiophlomis rotata (Lamiaceae), a perennial medicinal herb, is endemic to the Qinghai-Tibet Plateau. A total of 188 individuals from eight natural populations of L...
  43. Craig P, Li T, Qiu J, Zhen R, Wang Q, Giraudoux P, et al. Echinococcosis and Tibetan communities. Emerg Infect Dis. 2008;14:1674-5 pubmed publisher
  44. Xiang Z, Huo S, Xiao W, Quan R, Grueter C. Diet and feeding behavior of Rhinopithecus bieti at Xiaochangdu, Tibet: adaptations to a marginal environment. Am J Primatol. 2007;69:1141-58 pubmed
    ..snub-nosed monkeys (Rhinopithecus bieti) were studied at Xiaochangdu in Honglaxueshan Nature Reserve, Tibet. This region is climatologically harsher than any other inhabited by non-human primates...
  45. Huang Y, Yang W, Qiu J, Chen X, Yang Y, Qiu D, et al. A modified coproantigen test used for surveillance of Echinococcus spp. in Tibetan dogs. Vet Parasitol. 2007;149:229-38 pubmed
    ..This coproantigen technique is now being used as part of the Chinese National Hydatid Disease Control Program, initially in 10 counties in Sichuan Province. ..
  46. Jin C, Yan Z, Jianwei L, Ruodeng X, Sangbu D. Environmental fluoride content in Tibet. Environ Res. 2000;83:333-7 pubmed
    As the first report of the environmental fluoride level in Tibet, the determination by the fluoride ion-selective electrode method of fluoride concentration in water, soil, fuel, grains, food, vegetables, and tea was made for the Tibetan ..
  47. Hoy D, Toole M, Morgan D, Morgan C. Low back pain in rural Tibet. Lancet. 2003;361:225-6 pubmed
    In a baseline assessment of 30 rural villages surrounding Shigatse City, Tibet, many people, especially women, identified low back pain as a serious health problem...
  48. Cui C, Shi J, Hui L, Xi H, Zhuoma -, Quni -, et al. The dominant hepatitis B virus genotype identified in Tibet is a C/D hybrid. J Gen Virol. 2002;83:2773-7 pubmed
    There are no reports on DNA sequences of hepatitis B virus (HBV) strains from Tibet, although this highland area has a high HBsAg-positive population. We characterized HBV isolates from sera of 26 HBsAg-positive Tibetans...
  49. Liu J, Gao T, Chen Z, Lu A. Molecular phylogeny and biogeography of the Qinghai-Tibet Plateau endemic Nannoglottis (Asteraceae). Mol Phylogenet Evol. 2002;23:307-25 pubmed
    All taxa endemic to the Qinghai-Tibet Plateau are hypothesized to have originated in situ or from immediately adjacent areas because of the relatively recent formation of the plateau since the Pliocene, followed by the large-scaled biota ..
  50. Hinsenkamp M, Ryppens F, Begaux F, Mathieu F, de Maertelaer V, Lepeire M, et al. The anatomical distribution of radiological abnormalities in Kashin-Beck disease in Tibet. Int Orthop. 2001;25:142-6 pubmed
    ..5% of cases. The radiological changes and their distribution might be explained by the hypothesis of inhibition of angiogenesis by mycotoxins, exacerbated by chemical and physical environmental factors. ..
  51. Wen B, Jian R, Zhang Y, Chen R. Simultaneous detection of Anaplasma marginale and a new Ehrlichia species closely related to Ehrlichia chaffeensis by sequence analyses of 16S ribosomal DNA in Boophilus microplus ticks from Tibet. J Clin Microbiol. 2002;40:3286-90 pubmed
    To identify ehrlichial agents in Boophilus microplus ticks, DNA samples of B. microplus collected from the Tibet Autonomous Region and Sichuan Province of China were screened by a nested PCR. Sixteen of 43 (37%) DNA samples of B...
  52. Mathieu F, Suetens C, Begaux F, de Maertelaer V, Hinsenkamp M. Effects of physical therapy on patients with Kashin-Beck disease in Tibet. Int Orthop. 2001;25:191-3 pubmed
    ..trial of physical therapy treatment for patients suffering from Kashin-Beck disease (KBD) has been carried out in Tibet. One-hundred and thirty-five patients with Kashin-Beck disease were allocated to either physical therapy (72 ..
  53. Moreno Reyes R, Suetens C, Mathieu F, Begaux F, Zhu D, Rivera T, et al. Kashin-Beck disease and iodine deficiency in Tibet. Int Orthop. 2001;25:164-6 pubmed
    ..The results suggest that in areas where severe selenium deficiency is endemic, iodine deficiency is a risk factor for Kashin-Beck disease. ..