genome size


Summary: The amount of DNA (or RNA) in one copy of a genome.

Top Publications

  1. Chen Z, Grover C, Li P, Wang Y, Nie H, Zhao Y, et al. Molecular evolution of the plastid genome during diversification of the cotton genus. Mol Phylogenet Evol. 2017;112:268-276 pubmed publisher
    ..This research provides an overview of the molecular evolution of a single, large non-recombining molecular during the diversification of this important genus. ..
  2. Pais M, Win J, Yoshida K, Etherington G, Cano L, Raffaele S, et al. From pathogen genomes to host plant processes: the power of plant parasitic oomycetes. Genome Biol. 2013;14:211 pubmed publisher
    ..Recent pathogenomic research on plant parasitic oomycete effector function and plant host responses has resulted in major conceptual advances in plant pathology, which has been possible thanks to the availability of genome sequences. ..
  3. Siljak Yakovlev S, Godelle B, Zoldos V, Vallès J, Garnatje T, Hidalgo O. Evolutionary implications of heterochromatin and rDNA in chromosome number and genome size changes during dysploidy: A case study in Reichardia genus. PLoS ONE. 2017;12:e0182318 pubmed publisher
    ..During this process, a positive correlation was observed between chromosome number and genome size, rDNA loci number and pollen size, although only the correlation between chromosome number and genome size is ..
  4. Schwarz E, Korhonen P, Campbell B, Young N, Jex A, Jabbar A, et al. The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus. Genome Biol. 2013;14:R89 pubmed publisher
    ..This first draft genome of any strongylid nematode paves the way for a rapid acceleration in our understanding of a wide range of socioeconomically important parasites of one of the largest nematode orders. ..
  5. Igea J, Miller E, Papadopulos A, Tanentzap A. Seed size and its rate of evolution correlate with species diversification across angiosperms. PLoS Biol. 2017;15:e2002792 pubmed publisher
    ..Our study now reveals that variation in morphological traits and, importantly, the rate at which they evolve can contribute to explaining the extremely uneven distribution of diversity across the ToL. ..
  6. Veleba A, Bures P, Adamec L, Smarda P, Lipnerová I, Horova L. Genome size and genomic GC content evolution in the miniature genome-sized family Lentibulariaceae. New Phytol. 2014;203:22-8 pubmed publisher
  7. Lobkovsky A, Wolf Y, Koonin E. Estimation of prokaryotic supergenome size and composition from gene frequency distributions. BMC Genomics. 2014;15 Suppl 6:S14 pubmed publisher
  8. Lower S, Johnston J, Stanger Hall K, Hjelmen C, Hanrahan S, Korunes K, et al. Genome Size in North American Fireflies: Substantial Variation Likely Driven by Neutral Processes. Genome Biol Evol. 2017;9:1499-1512 pubmed publisher
    Eukaryotic genomes show tremendous size variation across taxa. Proximate explanations for genome size variation include differences in ploidy and amounts of noncoding DNA, especially repetitive DNA...
  9. Wang L, Fu S, Cao Y, Zhang H, Feng Y, Yang W, et al. Discovery and genetic analysis of novel coronaviruses in least horseshoe bats in southwestern China. Emerg Microbes Infect. 2017;6:e14 pubmed publisher

More Information


  1. Gualberto J, Newton K. Plant Mitochondrial Genomes: Dynamics and Mechanisms of Mutation. Annu Rev Plant Biol. 2017;68:225-252 pubmed publisher
    ..We review the present state of knowledge of the genes and pathways underlying mitochondrial genome stability. ..
  2. Kamminga T, Koehorst J, Vermeij P, Slagman S, Martins Dos Santos V, Bijlsma J, et al. Persistence of Functional Protein Domains in Mycoplasma Species and their Role in Host Specificity and Synthetic Minimal Life. Front Cell Infect Microbiol. 2017;7:31 pubmed publisher
    ..This study provides a concise overview of the functional capabilities of mycoplasma species, which can be used as a basis to further understand host-pathogen interaction or to design synthetic minimal life...
  3. Huang Y, Cho S, Haryono M, Kuo C. Complete chloroplast genome sequence of common bermudagrass (Cynodon dactylon (L.) Pers.) and comparative analysis within the family Poaceae. PLoS ONE. 2017;12:e0179055 pubmed publisher
  4. Feitoza L, Costa L, Guerra M. Condensation patterns of prophase/prometaphase chromosome are correlated with H4K5 histone acetylation and genomic DNA contents in plants. PLoS ONE. 2017;12:e0183341 pubmed publisher
    ..condensation patterns (CPs) of prophase and prometaphase chromosomes and investigated their relationship with genome size and distribution of histone H4 acetylated at lysine 5 (H4K5ac) in 17 plant species...
  5. Eddy S. The C-value paradox, junk DNA and ENCODE. Curr Biol. 2012;22:R898-9 pubmed publisher
  6. De Lazzari E, Grilli J, Maslov S, Cosentino Lagomarsino M. Family-specific scaling laws in bacterial genomes. Nucleic Acids Res. 2017;45:7615-7622 pubmed publisher
    ..Specifically, the number of proteins within each family follows family-specific scaling laws with genome size. Functionally similar sets of families tend to follow similar scaling laws, but this is not always the case...
  7. Fang C, Chang Y, Chung W, Hsieh P, Lin C, Ho J. Subset selection of high-depth next generation sequencing reads for de novo genome assembly using MapReduce framework. BMC Genomics. 2015;16 Suppl 12:S9 pubmed publisher
    ..The results show that subset selection not only can speed up the genome assembly but also can produce substantially longer scaffolds. The software is freely available at ..
  8. Jeffery N, Yampolsky L, Gregory T. Nuclear DNA content correlates with depth, body size, and diversification rate in amphipod crustaceans from ancient Lake Baikal, Russia. Genome. 2017;60:303-309 pubmed publisher
    ..Specifically, we report genome size estimates for 36 species of Baikal amphipods, and examine the relationship between genome size, body size, and ..
  9. Cramaro W, Hunewald O, Bell Sakyi L, Muller C. Genome scaffolding and annotation for the pathogen vector Ixodes ricinus by ultra-long single molecule sequencing. Parasit Vectors. 2017;10:71 pubmed publisher
    ..In addition, we present the first genome size estimation for I. ricinus ticks and the embryo-derived cell line IRE/CTVM19...
  10. Wefferling K, Castro S, Loureiro J, Castro M, Tavares D, Hoot S. Cytogeography of the subalpine marsh marigold polyploid complex (Caltha leptosepala s.l., Ranunculaceae). Am J Bot. 2017;104:271-285 pubmed publisher
    ..leptosepala s.l. Genome size estimates from flow cytometry were used to infer cytotypes...
  11. Tejerizo G, Kim Y, Maus I, Wibberg D, Winkler A, Off S, et al. Genome sequence of Methanobacterium congolense strain Buetzberg, a hydrogenotrophic, methanogenic archaeon, isolated from a mesophilic industrial-scale biogas plant utilizing bio-waste. J Biotechnol. 2017;247:1-5 pubmed publisher
    ..Compilation of specific genes among Methanobacterium strains originating from AD environments revealed 474 genetic determinants that could be crucial for adaptation of these strains to specific conditions prevailing in AD habitats. ..
  12. Koren S, Harhay G, Smith T, Bono J, Harhay D, Mcvey S, et al. Reducing assembly complexity of microbial genomes with single-molecule sequencing. Genome Biol. 2013;14:R101 pubmed
    ..This is expected to increase the number of completed genomes, improve the quality of microbial genome databases, and enable high-fidelity, population-scale studies of pan-genomes and chromosomal organization. ..
  13. Pang T, Ye C, Xia X, Yin W. De novo sequencing and transcriptome analysis of the desert shrub, Ammopiptanthus mongolicus, during cold acclimation using Illumina/Solexa. BMC Genomics. 2013;14:488 pubmed publisher
    ..Studies of differentially expressed genes involved in cold-related metabolic pathways and transcription factors facilitate the discovery of cold-resistance genes. ..
  14. Fraser T, Shao R, Fountain Jones N, Charleston M, Martin A, Whiteley P, et al. Mitochondrial genome sequencing reveals potential origins of the scabies mite Sarcoptes scabiei infesting two iconic Australian marsupials. BMC Evol Biol. 2017;17:233 pubmed publisher
    ..If this is the case, comparable patterns may exist elsewhere in the 'New World'. This work provides a basis for expanded molecular studies into mange epidemiology in humans and animals in Australia and other geographic regions. ..
  15. Jeffery N, Ellis E, Oakley T, Gregory T. The Genome Sizes of Ostracod Crustaceans Correlate with Body Size and Evolutionary History, but not Environment. J Hered. 2017;108:701-706 pubmed publisher
    Within animals, a positive correlation between genome size and body size has been detected in several taxa but not in others, such that it remains unknown how pervasive this pattern may be...
  16. Yoshida Y, Koutsovoulos G, Laetsch D, Stevens L, Kumar S, Horikawa D, et al. Comparative genomics of the tardigrades Hypsibius dujardini and Ramazzottius varieornatus. PLoS Biol. 2017;15:e2002266 pubmed publisher
    ..Whole-genome molecular phylogenies supported a Tardigrada+Nematoda relationship over Tardigrada+Arthropoda, but rare genomic changes tended to support Tardigrada+Arthropoda. ..
  17. Tan B, Yang X, Ge X, Peng C, Liu H, Zhang Y, et al. Novel bat adenoviruses with low G+C content shed new light on the evolution of adenoviruses. J Gen Virol. 2017;98:739-748 pubmed publisher
    ..We further analysed the relationships among the G+C content, 5'-C-phosphate-G-3' (CpG) representation and genome size in the family Adenoviridae...
  18. Feijão P, Martinez F, Thévenin A. On the distribution of cycles and paths in multichromosomal breakpoint graphs and the expected value of rearrangement distance. BMC Bioinformatics. 2015;16 Suppl 19:S1 pubmed publisher
  19. Fischer M, Condit R. Editorial introduction to "Giant Viruses" special issue of Virology. Virology. 2014;466-467:1-2 pubmed publisher
  20. Xiao J, Yue Z, Jia L, Yang X, Niu L, Wang Z, et al. Obligate mutualism within a host drives the extreme specialization of a fig wasp genome. Genome Biol. 2013;14:R141 pubmed publisher
    ..We sequenced the genome of the fig wasp Ceratosolen solmsi to address this question. The genome size of the fig wasp C...
  21. Sierro N, Battey J, Ouadi S, Bovet L, Goepfert S, Bakaher N, et al. Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana tomentosiformis. Genome Biol. 2013;14:R60 pubmed publisher
  22. Nayfach S, Pollard K. Average genome size estimation improves comparative metagenomics and sheds light on the functional ecology of the human microbiome. Genome Biol. 2015;16:51 pubmed publisher
    Average genome size is an important, yet often overlooked, property of microbial communities...
  23. Bainard J, Gregory T. Genome size evolution: patterns, mechanisms, and methodological advances. Genome. 2013;56:vii-viii pubmed publisher
  24. Leushkin E, Sutormin R, Nabieva E, Penin A, Kondrashov A, Logacheva M. The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences. BMC Genomics. 2013;14:476 pubmed publisher
    Genlisea aurea (Lentibulariaceae) is a carnivorous plant with unusually small genome size - 63.6 Mb - one of the smallest known among higher plants...
  25. Motamayor J, Mockaitis K, Schmutz J, Haiminen N, Livingstone D, Cornejo O, et al. The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color. Genome Biol. 2013;14:r53 pubmed publisher
    ..We report a high-quality sequence and annotation of Theobroma cacao L. and demonstrate its utility in identifying candidate genes regulating traits. ..