honey

Summary

Summary: A sweet viscous liquid food, produced in the honey sacs of various bees from nectar collected from flowers. The nectar is ripened into honey by inversion of its sucrose sugar into fructose and glucose. It is somewhat acidic and has mild antiseptic properties, being sometimes used in the treatment of burns and lacerations.

Top Publications

  1. Truzzi C, Annibaldi A, Illuminati S, Finale C, Rossetti M, Scarponi G. Determination of very low levels of 5-(hydroxymethyl)-2-furaldehyde (HMF) in natural honey: comparison between the HPLC technique and the spectrophotometric white method. J Food Sci. 2012;77:C784-90 pubmed publisher
    In this work we compared 2 official methods for the determination of HMF in honey, the spectrophotometric White method and the HPLC method (International Honey Commission) for the determination of HMF in unifloral honey and honeydew ..
  2. Chua L, Abdul Rahaman N, Sarmidi M, Aziz R. Multi-elemental composition and physical properties of honey samples from Malaysia. Food Chem. 2012;135:880-7 pubmed publisher
    The elemental profiles of six honey samples from Malaysia had been constructed using the data obtained from both ICP-AES and ICP-MS. Potassium and sodium were the most abundant minerals covering from 69.3-78.6% and 14.1-28...
  3. Fernandez Cabezudo M, El Kharrag R, Torab F, Bashir G, George J, El Taji H, et al. Intravenous administration of manuka honey inhibits tumor growth and improves host survival when used in combination with chemotherapy in a melanoma mouse model. PLoS ONE. 2013;8:e55993 pubmed publisher
    Manuka honey has been recognized for its anti-bacterial and wound-healing activity but its potential antitumor effect is poorly studied despite the fact that it contains many antioxidant compounds...
  4. Biesaga M, Pyrzynska K. Stability of bioactive polyphenols from honey during different extraction methods. Food Chem. 2013;136:46-54 pubmed publisher
    The LC-MS/MS technique was applied to the stability study of several flavonoids and phenolic acids in honey samples during the ultrasonic extraction (USE) and microwave-assisted extraction (MAE)...
  5. Jenkins R, Cooper R. Improving antibiotic activity against wound pathogens with manuka honey in vitro. PLoS ONE. 2012;7:e45600 pubmed publisher
    Following the discovery of synergistic action between oxacillin and manuka honey against methicillin-resistant Staphylococcus aureus, this study was undertaken to search for further synergistic combinations of antibiotics and honey that ..
  6. Di Girolamo F, D Amato A, Righetti P. Assessment of the floral origin of honey via proteomic tools. J Proteomics. 2012;75:3688-93 pubmed publisher
    The honey from chestnut, acacia, sunflower, eucalyptus and orange was analysed for its proteome content, in order to see if any plant proteins present would allow the proteo-typing of these different varieties...
  7. Grembecka M, Szefer P. Evaluation of honeys and bee products quality based on their mineral composition using multivariate techniques. Environ Monit Assess. 2013;185:4033-47 pubmed publisher
    ..There was a significant influence of the botanical and geographical provenance as well as technological processing on the elemental composition of honeys. ..
  8. Atrott J, Haberlau S, Henle T. Studies on the formation of methylglyoxal from dihydroxyacetone in Manuka (Leptospermum scoparium) honey. Carbohydr Res. 2012;361:7-11 pubmed publisher
    Dihydroxyacetone (DHA) and methylglyoxal (MGO) are unique carbohydrate metabolites of manuka honey. A method for the reliable quantification of DHA in honey samples was established, based on derivatization with o-phenylenediamine (OPD) ..
  9. Zhou N, Wang J, Zhang J, Li C, Tian Y, Wang J. Selection and identification of streptomycin-specific single-stranded DNA aptamers and the application in the detection of streptomycin in honey. Talanta. 2013;108:109-16 pubmed publisher
    ..Furthermore, the established method was utilized to detect streptomycin in honey, and the same low detection limit and linear detection range were achieved.

More Information

Publications62

  1. Zainol M, Mohd Yusoff K, Mohd Yusof M. Antibacterial activity of selected Malaysian honey. BMC Complement Altern Med. 2013;13:129 pubmed publisher
    Antibacterial activity of honey is mainly dependent on a combination of its peroxide activity and non-peroxide components...
  2. Cingolani P, Cao X, Khetani R, Chen C, Coon M, Sammak A, et al. Intronic non-CG DNA hydroxymethylation and alternative mRNA splicing in honey bees. BMC Genomics. 2013;14:666 pubmed publisher
    Previous whole-genome shotgun bisulfite sequencing experiments showed that DNA cytosine methylation in the honey bee (Apis mellifera) is almost exclusively at CG dinucleotides in exons...
  3. Hawley P, Hovan A, McGahan C, Saunders D. A randomized placebo-controlled trial of manuka honey for radiation-induced oral mucositis. Support Care Cancer. 2014;22:751-61 pubmed publisher
    ..Some small studies have suggested that organic honey may be a useful preventive treatment...
  4. Paradis D, Bérail G, Bonmatin J, Belzunces L. Sensitive analytical methods for 22 relevant insecticides of 3 chemical families in honey by GC-MS/MS and LC-MS/MS. Anal Bioanal Chem. 2014;406:621-33 pubmed publisher
    Several methods for analyzing pesticides in honey have been developed. However, they do not always reach the sufficiently low limits of quantification (LOQ) needed to quantify pesticides toxic to honey bees at low doses...
  5. Maddocks S, Lopez M, Rowlands R, Cooper R. Manuka honey inhibits the development of Streptococcus pyogenes biofilms and causes reduced expression of two fibronectin binding proteins. Microbiology. 2012;158:781-90 pubmed publisher
    ..Manuka honey has broad spectrum antimicrobial activity and its use in the clinical setting is beginning to gain acceptance with ..
  6. Roberts A, Maddocks S, Cooper R. Manuka honey is bactericidal against Pseudomonas aeruginosa and results in differential expression of oprF and algD. Microbiology. 2012;158:3005-13 pubmed publisher
    ..Manuka honey has gained ground in clinical settings due to its effective therapeutic action and broad spectrum of antibacterial ..
  7. Zaid S, Sulaiman S, Othman N, Soelaiman I, Shuid A, Mohamad N, et al. Protective effects of Tualang honey on bone structure in experimental postmenopausal rats. Clinics (Sao Paulo). 2012;67:779-84 pubmed
    The objective of this study was to evaluate the effects of Tualang honey on trabecular structure and compare these effects with those of calcium supplementation in ovariectomized rats...
  8. Küster T, Zumkehr B, Hermann C, Theurillat R, Thormann W, Gottstein B, et al. Voluntary ingestion of antiparasitic drugs emulsified in honey represents an alternative to gavage in mice. J Am Assoc Lab Anim Sci. 2012;51:219-23 pubmed
    ..The benzimidazole derivative albendazole was emulsified in commercially available honey and administered to mice by voluntary feeding or gavage...
  9. Abdulrhman M, Elbarbary N, Ahmed Amin D, Saeid Ebrahim R. Honey and a mixture of honey, beeswax, and olive oil-propolis extract in treatment of chemotherapy-induced oral mucositis: a randomized controlled pilot study. Pediatr Hematol Oncol. 2012;29:285-92 pubmed publisher
    ..Based on the observations that honey bees products have anti-inflammatory and wound healing effects, the present study tried to evaluate the effect of ..
  10. G tschenberger H, Gimple O, Tautz J, Beier H. Honey bee drones maintain humoral immune competence throughout all life stages in the absence of vitellogenin production. J Exp Biol. 2012;215:1313-22 pubmed publisher
    Drones are haploid male individuals whose major social function in honey bee colonies is to produce sperm and mate with a queen. In spite of their limited tasks, the vitality of drones is of utmost importance for the next generation...
  11. Majtan J, Klaudiny J, Bohova J, Kohutova L, Dzúrovä M, Sediva M, et al. Methylglyoxal-induced modifications of significant honeybee proteinous components in manuka honey: Possible therapeutic implications. Fitoterapia. 2012;83:671-7 pubmed publisher
    Methylglyoxal (MGO) is a major antibacterial component of manuka honey. Another antibacterial component found in Revamil honey, peptide defensin1, was not identified in manuka honey...
  12. Ahmad T, Jubri Z, Rajab N, Rahim K, Yusof Y, Makpol S. Gelam honey protects against gamma-irradiation damage to antioxidant enzymes in human diploid fibroblasts. Molecules. 2013;18:2200-11 pubmed publisher
    The present study was designed to determine the radioprotective effects of Malaysian Gelam honey on gene expression and enzyme activity of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) of human diploid ..
  13. Ciarlo T, Mullin C, Frazier J, Schmehl D. Learning impairment in honey bees caused by agricultural spray adjuvants. PLoS ONE. 2012;7:e40848 pubmed publisher
    ..b>Honey bees are exposed to a wide array of pesticides as they conduct normal foraging operations, meaning that they are ..
  14. Erejuwa O, Sulaiman S, Wahab M. Honey--a novel antidiabetic agent. Int J Biol Sci. 2012;8:913-34 pubmed publisher
    Diabetes mellitus remains a burden worldwide in spite of the availability of numerous antidiabetic drugs. Honey is a natural substance produced by bees from nectar...
  15. Aween M, Hassan Z, Muhialdin B, Eljamel Y, Al Mabrok A, Lani M. Antibacterial activity of Lactobacillus acidophilus strains isolated from honey marketed in Malaysia against selected multiple antibiotic resistant (MAR) Gram-positive bacteria. J Food Sci. 2012;77:M364-71 pubmed publisher
    A total of 32 lactic acid bacteria (LAB) were isolated from 13 honey samples commercially marketed in Malaysia, 6 strains identified as Lactobacillus acidophilus by API CHL50...
  16. Gómez Pérez M, Plaza Bolaños P, Romero González R, Martínez Vidal J, Garrido Frenich A. Comprehensive qualitative and quantitative determination of pesticides and veterinary drugs in honey using liquid chromatography-Orbitrap high resolution mass spectrometry. J Chromatogr A. 2012;1248:130-8 pubmed publisher
    ..quantitative purposes in routine analysis, after the optimization and validation of a generic extraction method in honey samples...
  17. Erejuwa O, Sulaiman S, Ab Wahab M, Sirajudeen K, Salleh S, Gurtu S. Honey supplementation in spontaneously hypertensive rats elicits antihypertensive effect via amelioration of renal oxidative stress. Oxid Med Cell Longev. 2012;2012:374037 pubmed publisher
    ..This study investigated the effect of honey on elevated systolic blood pressure (SBP) in spontaneously hypertensive rats (SHR)...
  18. Massaouti M, Daskalaki C, Gorodetsky A, Koulouklidis A, Tzortzakis S. Detection of harmful residues in honey using terahertz time-domain spectroscopy. Appl Spectrosc. 2013;67:1264-9 pubmed publisher
    ..spectroscopy (THz-TDS) has been applied for the detection and discrimination of harmful chemical residues in honey. Three antibiotics (sulfapyridine, sulfathiazole, and tetracycline) and two acaricides (coumaphos and amitraz) ..
  19. Johnson R, Mao W, Pollock H, Niu G, Schuler M, Berenbaum M. Ecologically appropriate xenobiotics induce cytochrome P450s in Apis mellifera. PLoS ONE. 2012;7:e31051 pubmed publisher
    b>Honey bees are exposed to phytochemicals through the nectar, pollen and propolis consumed to sustain the colony. They may also encounter mycotoxins produced by Aspergillus fungi infesting pollen in beebread...
  20. Kadir E, Sulaiman S, Yahya N, Othman N. Inhibitory effects of Tualang Honey on experimental breast cancer in rats: a preliminary study. Asian Pac J Cancer Prev. 2013;14:2249-54 pubmed
    The study was conducted to determine the effect of Malaysian jungle Tualang Honey (TH) on development of breast cancer induced by the carcinogen 7,12-dimethylbenz(?)anthracene (DMBA) in rats...
  21. Liu J, Ye Y, Lin T, Wang Y, Peng C. Effect of floral sources on the antioxidant, antimicrobial, and anti-inflammatory activities of honeys in Taiwan. Food Chem. 2013;139:938-43 pubmed publisher
    We evaluated the antioxidant, antibacterial, and anti-inflammatory activities of honey made from different floral sources, including the medicinal herb Bidens pilosa, fruit trees, Dimocarpus longan, Litchi chinensis, and Citrus maxima, ..
  22. Tirosh Y, Morpurgo N, Cohen M, Linial M, Bloch G. Raalin, a transcript enriched in the honey bee brain, is a remnant of genomic rearrangement in Hymenoptera. Insect Mol Biol. 2012;21:305-18 pubmed publisher
    We identified a predicted compact cysteine-rich sequence in the honey bee genome that we called 'Raalin'...
  23. Khalil I, Moniruzzaman M, Boukraa L, Benhanifia M, Islam A, Islam N, et al. Physicochemical and antioxidant properties of Algerian honey. Molecules. 2012;17:11199-215 pubmed
    The aim of the present study was to characterize the physical, biochemical and antioxidant properties of Algerian honey samples (n = 4)...
  24. Aparna S, Srirangarajan S, Malgi V, Setlur K, Shashidhar R, Setty S, et al. A comparative evaluation of the antibacterial efficacy of honey in vitro and antiplaque efficacy in a 4-day plaque regrowth model in vivo: preliminary results. J Periodontol. 2012;83:1116-21 pubmed publisher
    b>Honey has a potent broad-spectrum antibacterial action that may make it suitable for "anti-infective" treatment of periodontal disease...
  25. Strube Bloss M, Herrera Valdez M, Smith B. Ensemble response in mushroom body output neurons of the honey bee outpaces spatiotemporal odor processing two synapses earlier in the antennal lobe. PLoS ONE. 2012;7:e50322 pubmed publisher
    ..lobe (AL) - and a higher order multimodal integration and learning center - the mushroom body (MB) - in the honey bee brain...
  26. Belay A, Solomon W, Bultossa G, Adgaba N, Melaku S. Physicochemical properties of the Harenna forest honey, Bale, Ethiopia. Food Chem. 2013;141:3386-92 pubmed publisher
    In this study, the physicochemical properties of the Harenna forest honey were characterised...
  27. Ansari M, Al Ghamdi A, Usmani S, Al Waili N, Sharma D, Nuru A, et al. Effect of jujube honey on Candida albicans growth and biofilm formation. Arch Med Res. 2013;44:352-60 pubmed publisher
    ..The aim of this study was to evaluate the jujube (Zizyphus spina-christi) honey for its in vitro inhibitory activity against pre-formed biofilm and its interference with the biofilm formation of ..
  28. Alvarez Suarez J, Giampieri F, González Paramás A, Damiani E, Astolfi P, Martínez Sánchez G, et al. Phenolics from monofloral honeys protect human erythrocyte membranes against oxidative damage. Food Chem Toxicol. 2012;50:1508-16 pubmed publisher
    ..Overall, this study indicates that honey contains relevant antioxidant compounds responsible, at least in part, for its biological activity and that uptake ..
  29. Freiberg M, De Jong D, Message D, Cox Foster D. First report of sacbrood virus in honey bee (Apis mellifera) colonies in Brazil. Genet Mol Res. 2012;11:3310-4 pubmed publisher
    Sacbrood disease, an affliction of honey bees (Apis mellifera) characterized by brood that fails to pupate and subsequently dies, is an important threat to honey bee health...
  30. Moussa A, NourEddine D, Mohamed H, Abdelmelek M, Saad A. Antibacterial activity of various honey types of Algeria against Staphylococcus aureus and Streptococcus pyogenes. Asian Pac J Trop Med. 2012;5:773-6 pubmed publisher
    To assess the in vitro antibacterial activity of honey from different geographical location on Gram negative organisms...
  31. Islam A, Khalil I, Islam N, Moniruzzaman M, Mottalib A, Sulaiman S, et al. Physicochemical and antioxidant properties of Bangladeshi honeys stored for more than one year. BMC Complement Altern Med. 2012;12:177 pubmed publisher
    There is no available information on physicochemical and antioxidant properties on Bangladeshi honey. We investigated five different monofloral and three different multifloral honey samples collected from different parts of Bangladesh...
  32. Jenkins R, Cooper R. Synergy between oxacillin and manuka honey sensitizes methicillin-resistant Staphylococcus aureus to oxacillin. J Antimicrob Chemother. 2012;67:1405-7 pubmed publisher
    b>Honey is an ancient wound remedy that has recently been introduced into modern clinical practice in developed countries. Manuka honey inhibits growth of methicillin-resistant Staphylococcus aureus (MRSA) by preventing cell division...
  33. Foret S, Kucharski R, Pellegrini M, Feng S, Jacobsen S, Robinson G, et al. DNA methylation dynamics, metabolic fluxes, gene splicing, and alternative phenotypes in honey bees. Proc Natl Acad Sci U S A. 2012;109:4968-73 pubmed publisher
    In honey bees (Apis mellifera), the development of a larva into either a queen or worker depends on differential feeding with royal jelly and involves epigenomic modifications by DNA methyltransferases...
  34. Maddocks S, Jenkins R, Rowlands R, Purdy K, Cooper R. Manuka honey inhibits adhesion and invasion of medically important wound bacteria in vitro. Future Microbiol. 2013;8:1523-36 pubmed publisher
    To characterize the effect of manuka honey on medically important wound bacteria in vitro, focusing on its antiadhesive properties...
  35. Packer J, Irish J, Herbert B, Hill C, Padula M, Blair S, et al. Specific non-peroxide antibacterial effect of manuka honey on the Staphylococcus aureus proteome. Int J Antimicrob Agents. 2012;40:43-50 pubmed publisher
    Manuka honey, derived from the New Zealand flowering plant Leptospermum scoparium, shows promise as a topical antibacterial agent and effective chronic wound dressing...
  36. Dainat B, Evans J, Chen Y, Gauthier L, Neumann P. Predictive markers of honey bee colony collapse. PLoS ONE. 2012;7:e32151 pubmed publisher
    Across the Northern hemisphere, managed honey bee colonies, Apis mellifera, are currently affected by abrupt depopulation during winter and many factors are suspected to be involved, either alone or in combination...
  37. Erejuwa O, Sulaiman S, Ab Wahab M. Honey: a novel antioxidant. Molecules. 2012;17:4400-23 pubmed publisher
    ..b>Honey is a natural substance with many medicinal effects such as antibacterial, hepatoprotective, hypoglycemic, ..
  38. Botías C, Martín Hernández R, Barrios L, Meana A, Higes M. Nosema spp. infection and its negative effects on honey bees (Apis mellifera iberiensis) at the colony level. Vet Res. 2013;44:25 pubmed publisher
    ..caused by the microsporidia Nosema apis and Nosema ceranae are among the most common pathologies affecting adult honey bees. N...
  39. Mao W, Schuler M, Berenbaum M. Honey constituents up-regulate detoxification and immunity genes in the western honey bee Apis mellifera. Proc Natl Acad Sci U S A. 2013;110:8842-6 pubmed publisher
    As a managed pollinator, the honey bee Apis mellifera is critical to the American agricultural enterprise...
  40. Al Waili N, Al Ghamdi A, Ansari M, Al Attal Y, Salom K. Synergistic effects of honey and propolis toward drug multi-resistant Staphylococcus aureus, Escherichia coli and Candida albicans isolates in single and polymicrobial cultures. Int J Med Sci. 2012;9:793-800 pubmed publisher
    Propolis and honey are natural bee products with wide range of biological and medicinal properties...
  41. Raeessi M, Aslani J, Raeessi N, Gharaie H, Karimi Zarchi A, Raeessi F. Honey plus coffee versus systemic steroid in the treatment of persistent post-infectious cough: a randomised controlled trial. Prim Care Respir J. 2013;22:325-30 pubmed publisher
    ..Two of the suggested treatments for PPC are systemic steroid and honey plus coffee.
  42. Alvarez Suarez J, Giampieri F, Battino M. Honey as a source of dietary antioxidants: structures, bioavailability and evidence of protective effects against human chronic diseases. Curr Med Chem. 2013;20:621-38 pubmed
    In the long human tradition honey has been used not only as a nutrient but also as a medicine...
  43. Kato Y, Umeda N, Maeda A, Matsumoto D, Kitamoto N, Kikuzaki H. Identification of a novel glycoside, leptosin, as a chemical marker of manuka honey. J Agric Food Chem. 2012;60:3418-23 pubmed publisher
    As a preliminary study, we have found that honey from manuka (Leptospermum scoparium) in New Zealand inhibits myeloperoxidase (MPO) activity...
  44. Ahmad I, Jimenez H, Yaacob N, Yusuf N. Tualang honey protects keratinocytes from ultraviolet radiation-induced inflammation and DNA damage. Photochem Photobiol. 2012;88:1198-204 pubmed publisher
    Malaysian tualang honey possesses strong antioxidant and anti-inflammatory properties. Here, we evaluated the effect of tualang honey on early biomarkers of photocarcinogenesis employing PAM212 mouse keratinocyte cell line...
  45. Khalil M, Alam N, Moniruzzaman M, Sulaiman S, Gan S. Phenolic acid composition and antioxidant properties of Malaysian honeys. J Food Sci. 2011;76:C921-8 pubmed publisher
    ..and flavonoid contents of Malaysian Tualang, Gelam, and Borneo tropical honeys were compared to those of Manuka honey. Ferric reducing/antioxidant power assay (FRAP) and the 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical-scavenging ..
  46. Lambert O, Piroux M, Puyo S, Thorin C, Larhantec M, Delbac F, et al. Bees, honey and pollen as sentinels for lead environmental contamination. Environ Pollut. 2012;170:254-9 pubmed publisher
    ..Samples were collected during four different periods in both 2008 and 2009. Honey was the matrix the least contaminated by Pb (min = 0.004 ?g g(-1); max = 0.378 ?g g(-1); mean = 0...
  47. Erejuwa O, Sulaiman S, Wahab M. Fructose might contribute to the hypoglycemic effect of honey. Molecules. 2012;17:1900-15 pubmed publisher
    b>Honey is a natural substance with many medicinal properties, including antibacterial, hepatoprotective, hypoglycemic, antioxidant and antihypertensive effects. It reduces hyperglycemia in diabetic rats and humans...
  48. Kassim M, Yusoff K, Ong G, Sekaran S, Yusof M, Mansor M. Gelam honey inhibits lipopolysaccharide-induced endotoxemia in rats through the induction of heme oxygenase-1 and the inhibition of cytokines, nitric oxide, and high-mobility group protein B1. Fitoterapia. 2012;83:1054-9 pubmed publisher
    Malaysian Gelam honey has anti-inflammatory and antibacterial properties, a high antioxidant capacity, and free radical-scavenging activity...
  49. Zhou J, Li P, Cheng N, Gao H, Wang B, Wei Y, et al. Protective effects of buckwheat honey on DNA damage induced by hydroxyl radicals. Food Chem Toxicol. 2012;50:2766-73 pubmed publisher
    ..All the buckwheat honey samples possess stronger capability to protect DNA in the non-site-specific systems than in the site-specific ..
  50. Akanmu M, Olowookere T, Atunwa S, Ibrahim B, Lamidi O, Adams P, et al. Neuropharmacological effects of Nigerian honey in mice. Afr J Tradit Complement Altern Med. 2011;8:230-49 pubmed
    b>Honey is a natural sweet substance that bees produce by transforming flower nectar or other sweet secretions of plants. It has widespread use in traditional medicine in various parts of the world...
  51. Mat Lazim N, Abdullah B, Salim R. The effect of Tualang honey in enhancing post tonsillectomy healing process. An open labelled prospective clinical trial. Int J Pediatr Otorhinolaryngol. 2013;77:457-61 pubmed publisher
    ..Tualang honey has been shown to accelerate wound healing in postoperative patients...
  52. Johnson R, Dahlgren L, Siegfried B, Ellis M. Acaricide, fungicide and drug interactions in honey bees (Apis mellifera). PLoS ONE. 2013;8:e54092 pubmed publisher
    Chemical analysis shows that honey bees (Apis mellifera) and hive products contain many pesticides derived from various sources. The most abundant pesticides are acaricides applied by beekeepers to control Varroa destructor...
  53. Cohen H, Rozen J, Kristal H, Laks Y, Berkovitch M, Uziel Y, et al. Effect of honey on nocturnal cough and sleep quality: a double-blind, randomized, placebo-controlled study. Pediatrics. 2012;130:465-71 pubmed publisher
    To compare the effects of a single nocturnal dose of 3 honey products (eucalyptus honey, citrus honey, or labiatae honey) to placebo (silan date extract) on nocturnal cough and difficulty sleeping associated with childhood upper ..