dentinal fluid


Summary: The lymph or fluid of dentin. It is a transudate of extracellular fluid, mainly cytoplasm of odontoblastic processes, from the dental pulp via the dentinal tubules. It is also called dental lymph. (From Stedman, 26th ed, p665)

Top Publications

  1. Kolker J, Vargas M, Armstrong S, Dawson D. Effect of desensitizing agents on dentin permeability and dentin tubule occlusion. J Adhes Dent. 2002;4:211-21 pubmed
    ..The aim of this study was to evaluate: 1) the effect of five dentin desensitizing agents (DDAs) on permeability using hydraulic conductance, and 2) morphological tubule changes with scanning electron microscopy (SEM)...
  2. Ratih D, Palamara J, Messer H. Dentinal fluid flow and cuspal displacement in response to resin composite restorative procedures. Dent Mater. 2007;23:1405-11 pubmed
    The aim of this study was to correlate the rate and magnitude of dentinal fluid flow (DFF) with cuspal displacement in response to resin composite restorative procedures.
  3. Chidchuangchai W, Vongsavan N, Matthews B. Sensory transduction mechanisms responsible for pain caused by cold stimulation of dentine in man. Arch Oral Biol. 2007;52:154-60 pubmed
    ..Separate in vitro observations were made on the effects of these procedures on fluid flow through the dentine...
  4. Ozok A, Wu M, Wesselink P. Comparison of the in vitro permeability of human dentine according to the dentinal region and the composition of the simulated dentinal fluid. J Dent. 2002;30:107-11 pubmed
    ..To compare the permeability of the occlusal and the cervical dentinal regions within the same tooth, which represent the bottom of Class I and V cavities, respectively, with two different compositions of perfusion fluid, in vitro...
  5. Brodowski D, Imfeld T. [Dentin hypersensitivity--a review]. Schweiz Monatsschr Zahnmed. 2003;113:49-58 pubmed
  6. Orchardson R, Gillam D. Managing dentin hypersensitivity. J Am Dent Assoc. 2006;137:990-8; quiz 1028-9 pubmed
    ..The objective of this review is to inform practitioners about dentin hypersensitivity (DH) and its management. This clinical information is described in the context of the underlying biology...
  7. Linsuwanont P, Palamara J, Messer H. An investigation of thermal stimulation in intact teeth. Arch Oral Biol. 2007;52:218-27 pubmed
    ..To investigate the response of extracted intact teeth to thermal stimulation in terms of fluid movement, in relation to temperature change within tooth structure...
  8. Charoenlarp P, Wanachantararak S, Vongsavan N, Matthews B. Pain and the rate of dentinal fluid flow produced by hydrostatic pressure stimulation of exposed dentine in man. Arch Oral Biol. 2007;52:625-31 pubmed
    ..To determine the relationship between pain intensity and the rate of fluid flow through dentine in human subjects...
  9. Vongsavan N, Matthews B. The relationship between the discharge of intradental nerves and the rate of fluid flow through dentine in the cat. Arch Oral Biol. 2007;52:640-7 pubmed
    ..To investigate further the relationship between dentinal tubular flow and the discharge evoked in intradental nerves...

More Information

Publications123 found, 100 shown here

  1. Kim S, Ferracane J, Kim H, Lee I. Real-time measurement of dentinal fluid flow during amalgam and composite restoration. J Dent. 2010;38:343-51 pubmed publisher
    This study examined changes in the dentinal fluid flow (DFF) during restorative procedures and compared permeability after restoration among restorative materials and adhesives.
  2. Love R. The effect of tissue molecules on bacterial invasion of dentine. Oral Microbiol Immunol. 2002;17:32-7 pubmed
    ..It is suggested that this may be due to reduced dentine permeability as a consequence of the deposition of the compounds within dentinal tubules. ..
  3. Su K, Chang C, Chuang S, Ng E. The effect of dentinal fluid flow during loading in various directions--simulation of fluid-structure interaction. Arch Oral Biol. 2013;58:575-82 pubmed publisher
    ..pain should avoid measuring the bulk pulpal fluid flow from radicular pulp, but rather should measure the dentinal fluid flow in the dentinal tubules or coronal pulp...
  4. Oh S, Gu Y, Perinpanayagam H, Yoo Y, Lee Y, Kim R, et al. Dentinal tubule sealing effects of 532-nm diode-pumped solid-state laser, gallic acid/Fe3+ complex, and three commercial dentin desensitizers. Lasers Med Sci. 2018;33:1237-1244 pubmed publisher
    ..b>Dentinal fluid flow (DFF) was monitored continuously in real time during the application of each desensitizing agent, by ..
  5. Banomyong D, Palamara J, Burrow M, Messer H. Effect of dentin conditioning on dentin permeability and micro-shear bond strength. Eur J Oral Sci. 2007;115:502-9 pubmed
    ..b>Dentinal fluid flows at baseline and after conditioning were recorded for 15 min each...
  6. Markowitz K, Pashley D. Personal reflections on a sensitive subject. J Dent Res. 2007;86:292-5 pubmed
  7. Fujisawa M, Tokuda M, Morimoto Yamashita Y, Tatsuyama S, Arany S, Sugiyama T, et al. Hyperosmotic stress induces cell death in an odontoblast-lineage cell line. J Endod. 2012;38:931-5 pubmed publisher
    ..Inhibitors of 3 MAPKs inhibited the hyperosmotic stress-induced decline in cell viability at 500 and 700 mOsm. Hyperosmotic stress induces cell death of OLCs with sucrose through a MAPK pathway. ..
  8. Li Y, Ikeda H, Suda H. Determination of the functional space for fluid movement in the rat dentinal tubules using fluorescent microsphere. Arch Oral Biol. 2013;58:780-7 pubmed publisher
    ..1?m through which dentinal fluid can move, despite outward tapering of the dentinal tubules...
  9. Yiu C, Hiraishi N, Chersoni S, Breschi L, Ferrari M, Prati C, et al. Single-bottle adhesives behave as permeable membranes after polymerisation. II. Differential permeability reduction with an oxalate desensitiser. J Dent. 2006;34:106-16 pubmed
    ..However, reducing adhesive permeability with the use of oxalate desensitiser is not applicable to low acidity adhesives such as OptiBond Solo Plus and Prime and Bond NT. ..
  10. Seltzer S, Boston D. Hypersensitivity and pain induced by operative procedures and the "cracked tooth" syndrome. Gen Dent. 1997;45:148-59 pubmed
    ..Each operative condition is reviewed with respect to its etiology, symptomatology, and diagnosis. Some treatment recommendations are made to prevent or reduce symptoms. ..
  11. Marvin K. Bright, white, and sensitive: an overview of tooth whitening and dentin hypersensitivity. Dent Today. 2008;27:80-1 pubmed
  12. Tjäderhane L. The origin of enamel fluid. Eur J Oral Sci. 2007;115:522-3; author reply 523-4 pubmed
  13. Cummins D. Dentin hypersensitivity: from diagnosis to a breakthrough therapy for everyday sensitivity relief. J Clin Dent. 2009;20:1-9 pubmed
    ..This plug, which is resistant to normal pulpal pressures and to acid challenge, effectively reduces dentin fluid flow and, thereby, reduces sensitivity. ..
  14. Sidhu S, Agee K, Waller J, Pashley D. In vitro evaporative vs. convective water flux across human dentin before and after conditioning and placement of glass-ionomer cements. Am J Dent. 2004;17:211-5 pubmed
    ..These values were not significantly different when the specimens were stored for 24 hours. ..
  15. Nakajima M, Hosaka K, Yamauti M, Foxton R, Tagami J. Bonding durability of a self-etching primer system to normal and caries-affected dentin under hydrostatic pulpal pressure in vitro. Am J Dent. 2006;19:147-50 pubmed
    ..05). Hydrostatic pulpal pressure significantly reduced the bond strength to normal dentin after 1-month storage (P< 0.05), but did not affect the bond strength to caries-affected dentin. ..
  16. Burnett G, Willson R, Lucas R. In vitro studies investigating the dentin tubule-occlusion properties of an experimental anhydrous stannous fluoride dentifrice. Am J Dent. 2013;26 Spec No A:10A-14A pubmed
    ..The experimental stannous fluoride dentifrice was effective at reducing the hydraulic conductance of dentin by occluding tubules. The occlusion was resistant to challenge with grapefruit juice. ..
  17. Lin M, Luo Z, Bai B, Xu F, Lu T. Fluid mechanics in dentinal microtubules provides mechanistic insights into the difference between hot and cold dental pain. PLoS ONE. 2011;6:e18068 pubmed publisher
    ..a mathematical model based on the hypothesis that hot or cold stimulation-induced different directions of dentinal fluid flow and the corresponding odontoblast movements in dentinal microtubules contribute to different dental pain ..
  18. Sulkala M, Larmas M, Sorsa T, Salo T, Tjäderhane L. The localization of matrix metalloproteinase-20 (MMP-20, enamelysin) in mature human teeth. J Dent Res. 2002;81:603-7 pubmed
    ..By Western blotting, MMP-20 was detected in odontoblasts and pulp tissue of both sound and carious teeth, in dentinal fluid and dentin of sound teeth, but not in soft carious dentin...
  19. Mitchell J, Musanje L, Ferracane J. Biomimetic dentin desensitizer based on nano-structured bioactive glass. Dent Mater. 2011;27:386-93 pubmed publisher
    ..the ability of a novel sol-gel bioactive glass, in conjunction with appropriate carrier vehicles, to reduce dentinal fluid flow, with an eye toward reducing dentinal hypersensitivity...
  20. Tay F, Pashley D, Hiraishi N, Imazato S, Rueggeberg F, Salz U, et al. Tubular occlusion prevents water-treeing and through-and-through fluid movement in a single-bottle, one-step self-etch adhesive model. J Dent Res. 2005;84:891-6 pubmed
    ..However, the highly porous nature of this clinically relevant substrate after bonding may lead to potentially undesirable consequences. ..
  21. Sauro S, Watson T, Mannocci F, Tay F, Pashley D. Prevention of water contamination of ethanol-saturated dentin and hydrophobic hybrid layers. J Adhes Dent. 2009;11:271-8 pubmed
    ..Outward dentinal fluid flow may contaminate hybrid layers during adhesive bonding procedures...
  22. Grégoire G, Dabsie F, Delannée M, Akon B, Sharrock P. Water permeability, hybrid layer long-term integrity and reaction mechanism of a two-step adhesive system. J Dent. 2010;38:526-33 pubmed publisher
    ..The results showed the hydrophilicity of the adhesive, which formed an IPN-like hybrid layer that conserved adequate impermeability over a 1-year period. ..
  23. Love R, Jenkinson H. Invasion of dentinal tubules by oral bacteria. Crit Rev Oral Biol Med. 2002;13:171-83 pubmed
  24. Ardu S, Stavridakis M, Feilzer A, Krejci I, Lefever D, Dietschi D. Marginal adaptation of large adhesive class IV composite restorations before and after artificial aging. J Adhes Dent. 2011;13:425-31 pubmed publisher
    ..While under simulated dentinal fluid pressure, specimens were submitted to cyclic incisal stress (1,200,000 cycles, maximum load 49 N) and thermal ..
  25. Linsuwanont P, Palamara J, Messer H. Thermal transfer in extracted incisors during thermal pulp sensitivity testing. Int Endod J. 2008;41:204-10 pubmed
    ..Overall, dry ice and refrigerant spray provide the most consistent stimuli, whereas heated gutta-percha and hot water were highly variable. Ice was a weak stimulus. ..
  26. Mahdhaoui K, Fournier B, Derbanne M. Unbound monomers do diffuse through the dentin barrier. Dent Mater. 2017;33:743-751 pubmed publisher
    Assessing the role of dentinal fluid proteins in trans-dentinal diffusion of free monomers in vitro. An artificial pulp chamber (APC) topped human dentin disks was used...
  27. Stavridakis M, Kakaboura A, Ardu S, Krejci I. Marginal and internal adaptation of bulk-filled Class I and Cuspal coverage direct resin composite restorations. Oper Dent. 2007;32:515-23 pubmed
    ..The resin composite was placed and polymerized in one increment (bulk filling). Dentinal fluid was simulated using 1:3 diluted horse serum and fed into the pulp chamber both during restoration and ..
  28. Winston A, Charig A, Thong S. Mechanism of action of a desensitizing fluoride toothpaste delivering calcium and phosphate ingredients in the treatment of dental hypersensitivity. Part III: Prevention of dye penetration through dentin vs a calcium- and phosphate-free control. Compend Contin Educ Dent. 2010;31:46-8, 50-2 pubmed
    ..001) and objective (P < .01) measures. Tubule occlusion because of calcium and phosphate ions from the desensitizing toothpaste accounts for its tooth desensitizing efficacy. ..
  29. Youngson C, Jones J, Fox K, Smith I, Wood D, Gale M. A fluid filtration and clearing technique to assess microleakage associated with three dentine bonding systems. J Dent. 1999;27:223-33 pubmed
    ..Although not statistically significant, conditioning of the cavity increased the dentinal permeability but this effect was variable. Thermocycling had no statistically significant effect on microleakage. ..
  30. Wang Z, Shen Y, Haapasalo M. Effectiveness of endodontic disinfecting solutions against young and old Enterococcus faecalis biofilms in dentin canals. J Endod. 2012;38:1376-9 pubmed publisher
    ..faecalis biofilms in dentin canals using a novel dentin infection model and confocal laser scanning microscopy (CLSM)...
  31. Dietschi D, Duc O, Krejci I, Sadan A. Biomechanical considerations for the restoration of endodontically treated teeth: a systematic review of the literature--Part 1. Composition and micro- and macrostructure alterations. Quintessence Int. 2007;38:733-43 pubmed
  32. Shrestha A, Messer H, Asundi A, Kishen A. Effect of hydration on the strain gradients in dental hard tissues after heat and cold application. J Endod. 2010;36:1643-7 pubmed publisher
    ..The findings from this study highlighted the role of free water and structural characteristics of enamel, dentin, and DEJ in dissipating the thermal strains in the tooth. ..
  33. MacCarthy D. Dentine hypersensitivity: a review of the literature. J Ir Dent Assoc. 2004;50:36-41 pubmed
  34. Aziz A, Chandler N, Hauman C, Leichter J, McNaughton A, Tompkins G. Infection of apical dentin and root-end cavity disinfection. J Endod. 2012;38:1387-90 pubmed publisher
    ..E. faecalis invaded the entire width of dentin in the apical 3 mm irrespective of the smear layer and/or cementum. Chlorhexidine was more effective than laser in disinfecting root-end cavities. ..
  35. Izumi T, Inoue H, Matsuura H, Mukae F, Osoegawa H, Hirano H, et al. Changes in the pattern of horseradish peroxidase diffusion into predentin and dentin after cavity preparation in rat molars. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;92:675-81 pubmed
    ..Reparative dentin formation and subsequent impermeable junctional zone formation participate in the reduction of dentin permeability after cavity preparation. ..
  36. Al Sabbagh M, Brown A, Thomas M. In-office treatment of dentinal hypersensitivity. Dent Clin North Am. 2009;53:47-60, viii pubmed publisher
    ..Until such evidence is available, it seems prudent to employ therapies that are least likely to cause harm and are reversible. ..
  37. Mjor I. Dentin permeability: the basis for understanding pulp reactions and adhesive technology. Braz Dent J. 2009;20:3-16 pubmed
    ..It is not a review of the literature related to the permeability of dentin. Rather it presents interpretation of results related to the permeability of dentin based on experience and opinions acquired over a lifetime in dental research. ..
  38. Perdigao J. Dentin bonding-variables related to the clinical situation and the substrate treatment. Dent Mater. 2010;26:e24-37 pubmed publisher
    ..A new approach to stop the degradation of dentin-resin interfaces is the use of MMP inhibitors. Although still in an early phase of in vitro and clinical research, this method is promising. ..
  39. Addy M, Smith S. Dentin hypersensitivity: an overview on which to base tubule occlusion as a management concept. J Clin Dent. 2010;21:25-30 pubmed
  40. Cummins D. Recent advances in dentin hypersensitivity: clinically proven treatments for instant and lasting sensitivity relief. Am J Dent. 2010;23 Spec No A:3A-13A pubmed
    ..No difference in desensitizing efficacy was observed between the whitening and non-whitening versions. ..
  41. Southward K. The systemic theory of dental caries. Gen Dent. 2011;59:367-73; quiz 374-5 pubmed
    ..The healthy tooth is nourished by a centrifugal dentinal fluid flow...
  42. Chung G, Jung S, Oh S. Cellular and molecular mechanisms of dental nociception. J Dent Res. 2013;92:948-55 pubmed publisher
    ..Further understanding of the molecular mechanisms of dental pain would greatly enhance the development of therapeutics that target dental pain. ..
  43. Ozok A, Wu M, Wesselink P. The effects of post-extraction time on the hydraulic conductance of human dentine in vitro. Arch Oral Biol. 2002;47:41-6 pubmed
    ..These results suggest that the measurements were reproducible and that a steady phase of dentine permeability is established 9 days after extraction under these study conditions in vitro. ..
  44. Pashley D, Pashley E, Carvalho R, Tay F. The effects of dentin permeability on restorative dentistry. Dent Clin North Am. 2002;46:211-45, v-vi pubmed
  45. Ozok A, Wu M, De Gee A, Wesselink P. Effect of dentin perfusion on the sealing ability and microtensile bond strengths of a total-etch versus an all-in-one adhesive. Dent Mater. 2004;20:479-86 pubmed
    ..Due to excessive premature failure during sectioning, microTBS test could not be performed with Prompt L-Pop. Dentinal fluid flow may have detrimental effects on the sealing ability of dental adhesives depending on the type of adhesive ..
  46. Tavss E, Fisher S, Campbell S, Bonta Y, Darcy Siegel J, Blackwell B, et al. The scientific rationale and development of an optimized dentifrice for the treatment of dentin hypersensitivity. Am J Dent. 2004;17:61-70 pubmed
    ..In summary, a highly efficacious consumer friendly treatment for dentin hypersensitivity has been developed. ..
  47. Rosen B. A successful approach to whitening without dentinal sensitivity. Dent Today. 2005;24:62, 64 pubmed
  48. Rosales Leal J, de la Torre Moreno F, Bravo M. Effect of pulp pressure on the micropermeability and sealing ability of etch & rinse and self-etching adhesives. Oper Dent. 2007;32:242-50 pubmed
    ..In the gingival wall, Xeno obtained the best sealing, followed by Admira and Prime&Bond. Pulp fluid decreased gingival wall sealing when etch & rinse adhesives were used but not when self-etching adhesive was used. ..
  49. Vachiramon V, Vargas M, Pashley D, Tay F, Geraldeli S, Qian F, et al. Effects of oxalate on dentin bond after 3-month simulated pulpal pressure. J Dent. 2008;36:178-85 pubmed publisher
    ..The hypothesis tested was that oxalate restriction of dentinal fluid transudation when using an etch-and-rinse two-step adhesive will improve microtensile bond strength (muTBS) ..
  50. Wanachantararak S, Vongsavan N, Matthews B. Electrophysiological observations on the effects of potassium ions on the response of intradental nerves to dentinal tubular flow in the cat. Arch Oral Biol. 2011;56:294-305 pubmed publisher
  51. Magloire H, Maurin J, Couble M, Shibukawa Y, Tsumura M, Thivichon Prince B, et al. Topical review. Dental pain and odontoblasts: facts and hypotheses. J Orofac Pain. 2010;24:335-49 pubmed
    ..the underlying dental pulp via odontoblasts (dentin-forming cells), via their apical extension bathed in the dentinal fluid running in the tubules, or via a dense network of trigeminal sensory axons intimately related to odontoblasts...
  52. Sahin C, Cehreli Z, Yenigul M, Dayangac B. In vitro permeability of etch-and-rinse and self-etch adhesives used for immediate dentin sealing. Dent Mater J. 2012;31:401-8 pubmed
    ..The area and number of dentinal fluid droplets and/or blisters were calculated using image analysis...
  53. Tay F, Pashley D, Suh B, Carvalho R, Miller M. Single-step, self-etch adhesives behave as permeable membranes after polymerization. Part I. Bond strength and morphologic evidence. Am J Dent. 2004;17:271-8 pubmed
    ..When bonded to dehydrated dentin, delayed light-activation of the light-cured composite did not result in compromised bond strength. The results of chemical-cured composites improved but were more variable and system-dependent. ..
  54. Camps J, Salomon J, Meerbeek B, Tay F, Pashley D. Dentin deformation after scratching with clinically-relevant forces. Arch Oral Biol. 2003;48:527-34 pubmed
    ..pulpal mechanoreceptors, although it could induce sufficient elastic deformation to theoretically shift dentinal fluid at a rate sufficient to activate mechanoreceptors; (3)...
  55. Yuan Y, Shimada Y, Ichinose S, Sadr A, Tagami J. Effects of dentin characteristics on interfacial nanoleakage. J Dent Res. 2007;86:1001-6 pubmed
    ..The results did not support the null hypothesis. ..
  56. Zehnder M, Wegehaupt F, Attin T. A first study on the usefulness of matrix metalloproteinase 9 from dentinal fluid to indicate pulp inflammation. J Endod. 2011;37:17-20 pubmed publisher
    Pulpal diagnostics might be improved by using molecular markers found in dentinal fluid. In the current pilot study, we tested whether matrix metallopeptidase 9 (MMP-9) levels in dentinal fluid were detectable and differed between pulps ..
  57. Mjor I, Odont D. Pulp-dentin biology in restorative dentistry. Part 2: initial reactions to preparation of teeth for restorative procedures. Quintessence Int. 2001;32:537-51 pubmed
    ..Part 11 of this series discusses the structural and physiologic changes in the pulp-dentin complex that result from crown and cavity preparation and the clinical implication of these changes. ..
  58. Ozok A, de Gee A, Wu M, Wesselink P. The influence of resin composite and bonded amalgam restorations on dentine permeability in Class II cavities in vitro. Dent Mater. 2001;17:477-84 pubmed
  59. Elgalaid T, Youngson C, McHugh S, Hall A, Creanor S, Foye R. In vitro dentine permeability: the relative effect of a dentine bonding agent on crown preparations. J Dent. 2004;32:413-21 pubmed
    ..The DBA used did not seal dentinal tubules any more than did the smear layer and provisional crowns luted with a non-eugenol ZnO cement. ..
  60. Pereira J, Segala A, Gillam D. Effect of desensitizing agents on the hydraulic conductance of human dentin subjected to different surface pre-treatments--an in vitro study. Dent Mater. 2005;21:129-38 pubmed
  61. Abd Elmeguid A, Yu D. Dental pulp neurophysiology: part 1. Clinical and diagnostic implications. J Can Dent Assoc. 2009;75:55-9 pubmed
  62. Jacobsen P, Bruce G. Clinical dentin hypersensitivity: understanding the causes and prescribing a treatment. J Contemp Dent Pract. 2001;2:1-12 pubmed
    ..The third strategy is to desensitize the nerve tissue within the tubules using potassium nitrate. Several over-the-counter products are available to patients to treat this condition...
  63. Camps J, About I, Gouirand S, Franquin J. Dentin permeability and eugenol diffusion after full crown preparation. Am J Dent. 2003;16:112-6 pubmed
  64. Purk J, Dusevich V, Glaros A, Spencer P, Eick J. In vivo versus in vitro microtensile bond strength of axial versus gingival cavity preparation walls in Class II resin-based composite restorations. J Am Dent Assoc. 2004;135:185-93; quiz 228 pubmed
    ..The purpose of the authors' study was to compare the microtensile dentin bond strength of gingival and axial restored cavity preparation walls of Class II composite restorations under in vivo and in vitro conditions...
  65. Hashimoto M, Ito S, Tay F, Svizero N, Sano H, Kaga M, et al. Fluid movement across the resin-dentin interface during and after bonding. J Dent Res. 2004;83:843-8 pubmed
    ..The milder acid-etching effects of self-etching primers may retain hybridized smear plugs within the tubules that reduce outward fluid flow, resulting in superior dentin sealing...
  66. Tay F, Pashley D, Suh B, Hiraishi N, Yiu C. Water treeing in simplified dentin adhesives--déjà vu?. Oper Dent. 2005;30:561-79 pubmed
  67. Geraldeli S, Li Y, Hogan M, Tjaderhane L, Pashley D, Morgan T, et al. Inflammatory mediators in fluid extracted from the coronal occlusal dentine of trimmed teeth. Arch Oral Biol. 2012;57:264-70 pubmed publisher
    ..To test this hypothesis, we assessed the presence and concentration of inflammatory mediators in fluid extracted from the coronal occlusal dentine of trimmed teeth...
  68. Petersson L. The role of fluoride in the preventive management of dentin hypersensitivity and root caries. Clin Oral Investig. 2013;17 Suppl 1:S63-71 pubmed publisher
    ..The objectives were to bring light on fluoride to control dentin hypersensitivity (DHS) and prevent root caries...
  69. Gillam D, Chesters R, Attrill D, Brunton P, Slater M, Strand P, et al. Dentine hypersensitivity--guidelines for the management of a common oral health problem. Dent Update. 2013;40:514-6, 518-20, 523-4 pubmed
    ..Sensitivity associated with gingival recession, toothwear and periodontal disease and periodontal treatment are specifically addressed in the article. ..
  70. Ozok A, Wu M, Ten Cate J, Wesselink P. Effect of perfusion with water on demineralization of human dentin in vitro. J Dent Res. 2002;81:733-7 pubmed
    b>Dentinal fluid rarely features in caries studies of dentin. The mutual effects of in vitro perfusion and dentin demineralization were investigated...
  71. Kerdvongbundit V, Thiradilok S, Vongsavan N, Matthews B. The use of the replica technique to record fluid emerging from exposed dentine. Arch Oral Biol. 2004;49:613-9 pubmed
    ..With a pressure of + 30 mmHg in the pulp cavity, but not at the lower pressures, droplets were present on unetched dentine after 30s. Droplets accumulated less rapidly on etched dentine, indicating that it may act as a sponge...
  72. Ozok A, Wu M, Ten Cate J, Wesselink P. Effect of dentinal fluid composition on dentin demineralization in vitro. J Dent Res. 2004;83:849-53 pubmed
    Dentin demineralization is reduced by perfusion with water. We hypothesized that a simulated dentinal fluid (SDF) that contains albumin, in addition to electrolytes, would be more effective in reducing dentin demineralization than water ..
  73. Petrou I, Heu R, Stranick M, Lavender S, Zaidel L, Cummins D, et al. A breakthrough therapy for dentin hypersensitivity: how dental products containing 8% arginine and calcium carbonate work to deliver effective relief of sensitive teeth. J Clin Dent. 2009;20:23-31 pubmed
  74. Maamary S, De Moor R, Nammour S. [Treatment of dentin hypersensitivity by means of the Nd:YAG laser. Preliminary clinical study]. Rev Belge Med Dent (1984). 2009;64:140-6 pubmed
    ..39 J/cm2), rinsing and drying followed by a second smearing with the graphite, second lasing, rinsing, drying and a new evaluation of the pain immediately after the treatment and one week later...
  75. Itthagarun A, Tay F. Self-contamination of deep dentin by dentin fluid. Am J Dent. 2000;13:195-200 pubmed
  76. West N. Dentine hypersensitivity. Monogr Oral Sci. 2006;20:173-89 pubmed
    ..The basic principles of treatment are altering fluid flow in the dentinal tubules with tubule occlusion or modifying or blocking pulpal nerve response, chemically with agents like potassium or physically...
  77. Hahn C, Liewehr F. Relationships between caries bacteria, host responses, and clinical signs and symptoms of pulpitis. J Endod. 2007;33:213-9 pubmed
    ..The second purpose is to review how bacteria and their metabolites, as well as pulpal immune and inflammatory reactions to them, modify the pain sensation in pulpitis...
  78. Chandra S, Shankar P, Indira R. Depth of penetration of four resin sealers into radicular dentinal tubules: a confocal microscopic study. J Endod. 2012;38:1412-6 pubmed publisher
    ..The aim of this in vitro study was to evaluate the depth of penetration of 4 different endodontic resin sealers into the radicular dentinal tubules with the aid of confocal microscopy...
  79. Gregor L, Bortolotto T, Feilzer A, Krejci I. Shrinkage kinetics of a methacrylate- and a silorane-based resin composite: effect on marginal integrity. J Adhes Dent. 2013;15:245-50 pubmed publisher
    ..To evaluate the relation between the linear displacement (LD), shrinkage force (SF) and marginal adaptation of a methacrylate- and a silorane-based composite...
  80. Addy M, West N. The role of toothpaste in the aetiology and treatment of dentine hypersensitivity. Monogr Oral Sci. 2013;23:75-87 pubmed publisher
    ..Several toothpaste technologies formulated to block tubules are from studies in vitro, in situ and controlled clinical trials considered proven for the treatment of DH. ..
  81. Pashley D, Agee K, Zhang Y, Smith A, Tavss E, Gambogi R. The effects of outward forced convective flow on inward diffusion of potassium across human dentin. Am J Dent. 2002;15:256-61 pubmed
    ..To measure the inward flux of potassium across human dentin disks, in vitro, in the absence and then in the presence of a simulated pulpal pressure (PP), before and after brushing with two desensitizing dentifrices...
  82. Paes Leme A, dos Santos J, Giannini M, Wada R. Occlusion of dentin tubules by desensitizing agents. Am J Dent. 2004;17:368-72 pubmed
    ..To evaluate the occluding effect of five desensitizing agents on human dentin tubules...
  83. Larson T. The clinical significance and management of microleakage. Part one. Northwest Dent. 2005;84:23-5, 28-9, 31, passim pubmed
  84. Cardoso M, Moretto S, Carvalho R, Russo E. Influence of intrapulpal pressure simulation on the bond strength of adhesive systems to dentin. Braz Oral Res. 2008;22:170-5 pubmed
    ..It could be concluded that IPP simulation can influence the bond strength of certain adhesive systems to dentin and should be considered when in vitro studies are conducted...
  85. Ishihata H, Kanehira M, Nagai T, Finger W, Shimauchi H, Komatsu M. Effect of desensitizing agents on dentin permeability. Am J Dent. 2009;22:143-6 pubmed
    ..The tested hypothesis was that the products, in spite of different chemical mechanisms were not different at reducing or eliminating flow through dentin discs...
  86. Rusin R, Agee K, Suchko M, Pashley D. Effect of a new desensitizing material on human dentin permeability. Dent Mater. 2010;26:600-7 pubmed publisher
  87. Patel R, Chopra S, vandeVen M, Cummins D. Comparison of the effects on dentin permeability of two commercially available sensitivity relief dentifrices. J Clin Dent. 2011;22:108-12 pubmed
  88. da Rosa W, Lund R, Piva E, da Silva A. The effectiveness of current dentin desensitizing agents used to treat dental hypersensitivity: a systematic review. Quintessence Int. 2013;44:535-46 pubmed publisher
    ..A systematic review was conducted to analyze the clinical effectiveness of current desensitizer with at least 3 months of follow-up...
  89. Nahon M, Dentkos T, Nelson S, Gardner F, Rillman E. 2000 Judson C. Hickey Scientific Writing Award. Effect of impression materials on hybridized dentin. J Prosthet Dent. 2001;85:568-74 pubmed
    ..Tooth sensitivity after crown preparation is not an uncommon complication. For dentin bonding agents to be effective in preventing postoperative sensitivity, they must remain intact throughout the fixed prosthodontic procedures...
  90. Kleinberg I. SensiStat. A new saliva-based composition for simple and effective treatment of dentinal sensitivity pain. Dent Today. 2002;21:42-7 pubmed
  91. Tay F, Pashley D, Yiu C, Cheong C, Hashimoto M, Itou K, et al. Nanoleakage types and potential implications: evidence from unfilled and filled adhesives with the same resin composition. Am J Dent. 2004;17:182-90 pubmed
    ..Permeability of bonded dentin treated with OS and OSs was also examined...
  92. Chersoni S, Acquaviva G, Prati C, Ferrari M, Grandini S, Pashley D, et al. In vivo fluid movement through dentin adhesives in endodontically treated teeth. J Dent Res. 2005;84:223-7 pubmed
    ..Permeability of simplified adhesives results in water movement, even in root-treated dentin. This may adversely affect the coupling of auto-/dual-cured resin cements...