spindle poles

Summary

Summary: The sites in a dividing cell where the minus ends of the spindle MICROTUBULES assemble and where the separated sister CHROMATIDS converge.

Huhn S, Liu J, Ye C, Lu H, Jiang X, Feng X, et al. Regulation of spindle integrity and mitotic fidelity by BCCIP. Oncogene. 2017;36:4750-4766 pubmed publisher

..Our study identifies BCCIP as a novel factor critical for microtubule regulation and explicates a mechanism utilized by BCCIP in tumor suppression. ..
Jiang K, Rezabkova L, Hua S, Liu Q, Capitani G, Altelaar A, et al. Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex. Nat Cell Biol. 2017;19:480-492 pubmed publisher

..ASPM and katanin localize to spindle poles in a mutually dependent manner and regulate spindle flux...
Cheerambathur D, Prevo B, Hattersley N, Lewellyn L, Corbett K, Oegema K, et al. Dephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex. Dev Cell. 2017;41:424-437.e4 pubmed publisher
Nakaoka H, Wakamoto Y. Aging, mortality, and the fast growth trade-off of Schizosaccharomyces pombe. PLoS Biol. 2017;15:e2001109 pubmed publisher

..pombe and thus cannot be an appropriate molecular marker or index for replicative aging under both favorable and stressful environmental conditions. ..