glyoxysomes

Summary

Summary: Microbodies which occur in plant cells, and in some eukaryotic microorganisms, and which contain enzymes of the glyoxylate cycle. (Singleton and Stainsbury, Dictionary of Microbiology and Molecular Biology, 2nd ed)

Top Publications

  1. Michels P, Moyersoen J, Krazy H, Galland N, Herman M, Hannaert V. Peroxisomes, glyoxysomes and glycosomes (review). Mol Membr Biol. 2005;22:133-45 pubmed
    Peroxisomes, glyoxysomes and glycosomes are related organelles found in different organisms...
  2. Fukao Y, Hayashi M, Hara Nishimura I, Nishimura M. Novel glyoxysomal protein kinase, GPK1, identified by proteomic analysis of glyoxysomes in etiolated cotyledons of Arabidopsis thaliana. Plant Cell Physiol. 2003;44:1002-12 pubmed
    b>Glyoxysomes are present in etiolated cotyledons and contain enzymes for gluconeogenesis, which constitutes the major function of glyoxysomes...
  3. Gerhardt B, Fischer K, Balkenhohl T, Pohnert G, Kuhn H, Wasternack C, et al. Lipoxygenase-mediated metabolism of storage lipids in germinating sunflower cotyledons and beta-oxidation of (9Z,11E,13S)-13-hydroxy-octadeca-9,11-dienoic acid by the cotyledonary glyoxysomes. Planta. 2005;220:919-30 pubmed
    ..b>Glyoxysomes from etiolated sunflower cotyledons converted (9Z,11E,13S)-13-hydroxy-octadeca-9,11-dienoic acid to (9Z,11E)-13-..
  4. Diefenbach J, Kindl H. The membrane-bound DnaJ protein located at the cytosolic site of glyoxysomes specifically binds the cytosolic isoform 1 of Hsp70 but not other Hsp70 species. Eur J Biochem. 2000;267:746-54 pubmed
    DnaJ proteins are located in various compartments of the eukaryotic cell. As previously shown, peroxisomes and glyoxysomes possess a membrane-anchored form of DnaJ protein located on the cytosolic face...
  5. Hayashi Y, Hayashi M, Hayashi H, Hara Nishimura I, Nishimura M. Direct interaction between glyoxysomes and lipid bodies in cotyledons of the Arabidopsis thaliana ped1 mutant. Protoplasma. 2001;218:83-94 pubmed
    ..higher plants obtain energy from the glyconeogenic pathway in which fatty acids are converted to succinate in glyoxysomes, which contain enzymes for fatty acid beta-oxidation and the glyoxylate cycle...
  6. Managadze D, W rtz C, Sichting M, Niehaus G, Veenhuis M, Rottensteiner H. The peroxin PEX14 of Neurospora crassa is essential for the biogenesis of both glyoxysomes and Woronin bodies. Traffic. 2007;8:687-701 pubmed publisher
    In the filamentous fungus Neurospora crassa, glyoxysomes and Woronin bodies coexist in the same cell...
  7. Schumann U, Prestele J, O Geen H, Brueggeman R, Wanner G, Gietl C. Requirement of the C3HC4 zinc RING finger of the Arabidopsis PEX10 for photorespiration and leaf peroxisome contact with chloroplasts. Proc Natl Acad Sci U S A. 2007;104:1069-74 pubmed
    ..beta-Oxidation in mutant glyoxysomes was not affected...
  8. Goto Yamada S, Mano S, Oikawa K, Shibata M, Nishimura M. Interaction between chaperone and protease functions of LON2, and autophagy during the functional transition of peroxisomes. Plant Signal Behav. 2014;9:e28838 pubmed
    Functional transition of glyoxysomes to leaf peroxisomes is observed in greening cotyledons...
  9. Lopez Huertas E, Oh J, Baker A. Antibodies against pex14p block ATP-independent binding of matrix proteins to peroxisomes in vitro. FEBS Lett. 1999;459:227-9 pubmed
    ..Antibodies raised against human Pex14p recognise a 66 kDa protein in sunflower glyoxysomes (HaPex14p) and immunoprecipitate in vitro-translated Arabidopsis Pex14p (AtPex14p)...

More Information

Publications38

  1. Meyer D, Herrfurth C, Brodhun F, Feussner I. Degradation of lipoxygenase-derived oxylipins by glyoxysomes from sunflower and cucumber cotyledons. BMC Plant Biol. 2013;13:177 pubmed publisher
    ..For the involvement of a lipoxygenase previous results suggested that the hydroxy- or oxo-group that is being introduced into the fatty acid backbone by this lipoxygenase forms a barrier to continuous ?-oxidation...
  2. Pagnussat L, Burbach C, Baluska F, de la Canal L. An extracellular lipid transfer protein is relocalized intracellularly during seed germination. J Exp Bot. 2012;63:6555-63 pubmed publisher
    ..fraction of this LTP appears associated with oil bodies and some evidence also suggest its presence in glyoxysomes. So, HaAP10 is apoplastic in dry seeds and upon imbibition is rapidly internalized and relocalized to ..
  3. Liu X, Ma C, Subramani S. Recent advances in peroxisomal matrix protein import. Curr Opin Cell Biol. 2012;24:484-9 pubmed publisher
    ..They comprise a class of organelles called microbodies, including glycosomes, glyoxysomes and Woronin bodies...
  4. Helm M, Lück C, Prestele J, Hierl G, Huesgen P, Frohlich T, et al. Dual specificities of the glyoxysomal/peroxisomal processing protease Deg15 in higher plants. Proc Natl Acad Sci U S A. 2007;104:11501-6 pubmed
    b>Glyoxysomes are a subclass of peroxisomes involved in lipid mobilization. Two distinct peroxisomal targeting signals (PTSs), the C-terminal PTS1 and the N-terminal PTS2, are defined...
  5. Karyotou K, Donaldson R. Ascorbate peroxidase, a scavenger of hydrogen peroxide in glyoxysomal membranes. Arch Biochem Biophys. 2005;434:248-57 pubmed
    ..We investigated the contribution of the ascorbate enzyme system to the consumptions of H(2)O(2) and NADH within glyoxysomes of germinating castor beans (Ricinus communis)...
  6. Schiedel A, Oeljeklaus S, Minihan P, Dyer J. Cloning, expression, and purification of glyoxysomal 3-oxoacyl-CoA thiolase from sunflower cotyledons. Protein Expr Purif. 2004;33:25-33 pubmed publisher
    ..So far, this phenomenon has only been described for glyoxysomes from sunflower cotyledons. Thiolase I (acetoacetyl-CoA thiolase, EC 2.3.1...
  7. Corpas F, Sandalio L, Brown M, Del Rio L, Trelease R. Identification of porin-like polypeptide(s) in the boundary membrane of oilseed glyoxysomes. Plant Cell Physiol. 2000;41:1218-28 pubmed
    ..polypeptide of unknown function was identified by us in the boundary membrane fraction of cucumber seedling glyoxysomes. Evidence is presented in this study that this 36-kDa polypeptide is a glyoxysomal membrane porin...
  8. Palma K, Kermode A. Metabolism of hydrogen peroxide during reserve mobilization and programmed cell death of barley (Hordeum vulgare L.) aleurone layer cells. Free Radic Biol Med. 2003;35:1261-70 pubmed
    ..to aleurone cell death because of a compromised capacity to cope with reactive oxygen species generated by glyoxysomes and mitochondria...
  9. Nito K, Yamaguchi K, Kondo M, Hayashi M, Nishimura M. Pumpkin peroxisomal ascorbate peroxidase is localized on peroxisomal membranes and unknown membranous structures. Plant Cell Physiol. 2001;42:20-7 pubmed
    To investigate the roles of peroxisomal membrane proteins in the reversible conversion of glyoxysomes to leaf peroxisomes, we characterized several membrane proteins of glyoxysomes...
  10. Hayashi M, Toriyama K, Kondo M, Kato A, Mano S, De Bellis L, et al. Functional transformation of plant peroxisomes. Cell Biochem Biophys. 2000;32 Spring:295-304 pubmed
    Peroxisomes in higher plant cells are known to differentiate into at least three different classes, namely, glyoxysomes, leaf peroxisomes, and unspecialized peroxisomes, depending on the cell types...
  11. Hayashi H, De Bellis L, Hayashi Y, Nito K, Kato A, Hayashi M, et al. Molecular characterization of an Arabidopsis acyl-coenzyme a synthetase localized on glyoxysomal membranes. Plant Physiol. 2002;130:2019-26 pubmed
    ..These data suggested that AtLACS6 might play a regulatory role both in fatty acid import into glyoxysomes by making a complex with other factors, e.g. PMP70, and in fatty acid beta-oxidation activating the fatty acids.
  12. Afitlhile M, Fukushige H, Nishimura M, Hildebrand D. A defect in glyoxysomal fatty acid beta-oxidation reduces jasmonic acid accumulation in Arabidopsis. Plant Physiol Biochem. 2005;43:603-9 pubmed
    ..Thus, reduced levels of JA in the wounded tissues of the mutant were attributed to the defect in a thiolase protein...
  13. Prestele J, Hierl G, Scherling C, Hetkamp S, Schwechheimer C, Isono E, et al. Different functions of the C3HC4 zinc RING finger peroxins PEX10, PEX2, and PEX12 in peroxisome formation and matrix protein import. Proc Natl Acad Sci U S A. 2010;107:14915-20 pubmed publisher
    ..During seed germination, glyoxysomes form a reticulum around the lipid bodies for mobilization of storage oil...
  14. Bhatla S, Kaushik V, Yadav M. Use of oil bodies and oleosins in recombinant protein production and other biotechnological applications. Biotechnol Adv. 2010;28:293-300 pubmed publisher
    ..Artificial oil bodies can also be used for encapsulation of probiotics. The manipulation of oleosin gene for the expression of polyoleosins has further expanded the arena of the applications of oil bodies in biotechnology...
  15. Dunoyer P, Pfeffer S, Fritsch C, Hemmer O, Voinnet O, Richards K. Identification, subcellular localization and some properties of a cysteine-rich suppressor of gene silencing encoded by peanut clump virus. Plant J. 2002;29:555-67 pubmed
    ..The coiled-coil sequence is necessary for the anti-PTGS activity of P15, but the peroxisomal localization signal is not, although it is required for efficient intercellular movement of the virus...
  16. Dinis A, Coutinho A. Interaction of lipid bodies with other cell organelles in the maturing pollen of Magnolia x soulangeana (Magnoliaceae). Protoplasma. 2009;238:35-46 pubmed publisher
    ..and mature pollen showed a high percentage of lipid bodies establishing a physical contact with either glyoxysomes, either protein storage vacuoles, or small vesicles presumably originated from dictyosomes...
  17. Lammers P, Jun J, Abubaker J, Arreola R, Gopalan A, Bago B, et al. The glyoxylate cycle in an arbuscular mycorrhizal fungus. Carbon flux and gene expression. Plant Physiol. 2001;127:1287-98 pubmed
  18. Harrison Lowe N, Olsen L. Isolation of glyoxysomes from pumpkin cotyledons. Curr Protoc Cell Biol. 2006;Chapter 3:Unit 3.19 pubmed publisher
    ..In plants, there are several classes of peroxisomes. Glyoxysomes are found in germinating seedlings and contain enzymes specific for the glyoxylate cycle, including isocitrate ..
  19. Pracharoenwattana I, Smith S. When is a peroxisome not a peroxisome?. Trends Plant Sci. 2008;13:522-5 pubmed publisher
    ..seedlings now indicates that only two enzymes (isocitrate lyase and malate synthase) potentially distinguish glyoxysomes from other peroxisomes...
  20. Huang C, Chung C, Lin Y, Hsing Y, Huang A. Oil bodies and oleosins in Physcomitrella possess characteristics representative of early trends in evolution. Plant Physiol. 2009;150:1192-203 pubmed publisher
  21. Hayashi M, Nito K, Takei Hoshi R, Yagi M, Kondo M, Suenaga A, et al. Ped3p is a peroxisomal ATP-binding cassette transporter that might supply substrates for fatty acid beta-oxidation. Plant Cell Physiol. 2002;43:1-11 pubmed
    b>Glyoxysomes, a group of specialized peroxisomes, are organelles that degrade fatty acids by the combination of fatty acid beta-oxidation and glyoxylate cycle...
  22. Fukao Y, Hayashi Y, Mano S, Hayashi M, Nishimura M. Developmental analysis of a putative ATP/ADP carrier protein localized on glyoxysomal membranes during the peroxisome transition in pumpkin cotyledons. Plant Cell Physiol. 2001;42:835-41 pubmed
    ..These results clearly showed that the membrane protein PMP38 in glyoxysomes changes dramatically during the transformation of glyoxysomes to leaf peroxisomes, as do the other glyoxysomal ..
  23. Johnson T, Olsen L. Import of the peroxisomal targeting signal type 2 protein 3-ketoacyl-coenzyme a thiolase into glyoxysomes. Plant Physiol. 2003;133:1991-9 pubmed
    ..Finally, the addition of zinc to PTS2 protein imports increased the level of thiolase bound and imported into the organelles...
  24. Schliebs W, W rtz C, Kunau W, Veenhuis M, Rottensteiner H. A eukaryote without catalase-containing microbodies: Neurospora crassa exhibits a unique cellular distribution of its four catalases. Eukaryot Cell. 2006;5:1490-502 pubmed publisher
    ..We conclude that N. crassa lacks catalase-containing peroxisomes, a characteristic that is probably restricted to a few filamentous fungi that produce little hydrogen peroxide within microbodies...
  25. Oeljeklaus S, Fischer K, Gerhardt B. Glyoxysomal acetoacetyl-CoA thiolase and 3-oxoacyl-CoA thiolase from sunflower cotyledons. Planta. 2002;214:597-607 pubmed
    ..The thiolase activity of the glyoxysomes towards acetoacetyl-CoA and 3-oxopalmitoyl-CoA exceeded the glyoxysomal butyryl-CoA and palmitoyl-CoA beta-..
  26. Cox B, Chit M, Weaver T, Gietl C, Bailey J, Bell E, et al. Organelle and translocatable forms of glyoxysomal malate dehydrogenase. The effect of the N-terminal presequence. FEBS J. 2005;272:643-54 pubmed
    ..While no portion of the translocation sequences from either monomer in the biological dimer was visible, all of the other solution properties indicated measurable effects of the additional residues at the N-terminal...
  27. Hayashi M, Yagi M, Nito K, Kamada T, Nishimura M. Differential contribution of two peroxisomal protein receptors to the maintenance of peroxisomal functions in Arabidopsis. J Biol Chem. 2005;280:14829-35 pubmed
    ..Because of the functional differentiation, plant peroxisomes are subdivided into several classes, such as glyoxysomes and leaf peroxisomes...
  28. Sävenstrand H, Strid A. A Pisum sativum glyoxysomal malate dehydrogenase induced by cadmium exposure. DNA Seq. 2004;15:206-8 pubmed
    ..Exposure of pea plants to Cd2+ induced expression of the gMDH gene in mature pea leaves indicating that the enzyme is under environmental control in addition to the normal developmental regulation pattern...
  29. Kamada T, Nito K, Hayashi H, Mano S, Hayashi M, Nishimura M. Functional differentiation of peroxisomes revealed by expression profiles of peroxisomal genes in Arabidopsis thaliana. Plant Cell Physiol. 2003;44:1275-89 pubmed
    ..These data proposed more detailed description of differentiation of plant peroxisomes...