fetal diseases


Summary: Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES.

Top Publications

  1. Talkowski M, Ordulu Z, Pillalamarri V, Benson C, Blumenthal I, Connolly S, et al. Clinical diagnosis by whole-genome sequencing of a prenatal sample. N Engl J Med. 2012;367:2226-32 pubmed publisher
    ..This case study illustrates the potential power of customized whole-genome jumping libraries when used to augment prenatal karyotyping...
  2. Larsson A, Crang Svalenius E, Dykes A. Information for better or for worse: interviews with parents when their foetus was found to have choroid plexus cysts at a routine second trimester ultrasound. J Psychosom Obstet Gynaecol. 2009;30:48-57 pubmed publisher
    ..Some written information was also requested. It is of utmost importance that the staff use the same terminology and the correct name of the soft marker to the parents...
  3. Sivasli E, Teksam O, Haliloglu M, Gucer S, Orhan D, Gurgey A, et al. Hydrops fetalis associated with chorioangioma and thrombosis of umbilical vein. Turk J Pediatr. 2009;51:515-8 pubmed
    ..This is the first report of coexistence of non-immune hydrops fetalis with placental chorioangioma and thrombosis of an umbilical vein varix...
  4. Guo R, Hou W, Dong Y, Yu Z, Stites J, Weiner C. Brain injury caused by chronic fetal hypoxemia is mediated by inflammatory cascade activation. Reprod Sci. 2010;17:540-8 pubmed publisher
    ..We suggest CHX fetal brain injury is not directly caused by oxygen deprivation but rather is an adaptive response that becomes maladaptive...
  5. Morris R, Malin G, Khan K, Kilby M. Systematic review of the effectiveness of antenatal intervention for the treatment of congenital lower urinary tract obstruction. BJOG. 2010;117:382-90 pubmed publisher
    ..Congenital lower urinary tract obstruction is associated with high mortality and morbidity. Antenatal detection has improved with advances in ultrasound technology, and has allowed the option of antenatal intervention...
  6. Tomek V, Janousek J, Reich O, Gilík J, Gebauer R, Skovranek J. Atrioventricular conduction time in fetuses assessed by Doppler echocardiography. Physiol Res. 2011;60:611-6 pubmed
    ..One of 21 fetuses of mothers with positive autoantibodies was affected by prolonged atrioventricular interval according to the established limits, with sinus rhythm after the birth...
  7. Pavlinkova G, Salbaum J, Kappen C. Wnt signaling in caudal dysgenesis and diabetic embryopathy. Birth Defects Res A Clin Mol Teratol. 2008;82:710-9 pubmed publisher
    ..Given that there is also an at least threefold higher risk for heart defects and NTDs, it is important to identify the underlying molecular mechanisms for aberrant embryonic development...
  8. Danzer E, Gerdes M, Bebbington M, Sutton L, Melchionni J, Adzick N, et al. Lower extremity neuromotor function and short-term ambulatory potential following in utero myelomeningocele surgery. Fetal Diagn Ther. 2009;25:47-53 pubmed publisher
    ..To evaluate lower extremity neuromotor function (LENF) and short-term ambulatory potential following fetal myelomeningocele (fMMC) closure...
  9. Strasburger J, Wakai R. Fetal cardiac arrhythmia detection and in utero therapy. Nat Rev Cardiol. 2010;7:277-90 pubmed publisher
    ..This article reviews the current and future diagnostic techniques and pharmacologic treatments for fetal arrhythmia...

More Information

Publications101 found, 100 shown here

  1. Bourque D, Peñaherrera M, Yuen R, Van Allen M, McFadden D, Robinson W. The utility of quantitative methylation assays at imprinted genes for the diagnosis of fetal and placental disorders. Clin Genet. 2011;79:169-75 pubmed publisher
    ..These results also show the maintenance of imprinting status at these loci in the human placenta, even in the presence of abnormal pathology...
  2. Yang Y, Ma G, Shih J, Chen C, Chou C, Yeh K, et al. Experimental treatment of bilateral fetal chylothorax using in-utero pleurodesis. Ultrasound Obstet Gynecol. 2012;39:56-62 pubmed publisher
    ..To assess the use and efficacy of in-utero pleurodesis for experimental treatment of bilateral fetal chylothorax...
  3. Li X, Weng H, Xu C, Reece E, Yang P. Oxidative stress-induced JNK1/2 activation triggers proapoptotic signaling and apoptosis that leads to diabetic embryopathy. Diabetes. 2012;61:2084-92 pubmed publisher
    ..Our results show that JNK1 and JNK2 are equally involved in diabetic embryopathy and that the oxidative stress-JNK1/2-caspase pathway mediates the proapoptotic signals and the teratogenicity of maternal diabetes...
  4. Wilson R, Hedrick H, Flake A, Johnson M, Bebbington M, Mann S, et al. Sacrococcygeal teratomas: prenatal surveillance, growth and pregnancy outcome. Fetal Diagn Ther. 2009;25:15-20 pubmed publisher
    ..Prenatal surveillance and growth characteristics are evaluated in a cohort of fetuses with sacrococcygeal teratomas (SCT) as part of risk assessment...
  5. Morris R, Malin G, Khan K, Kilby M. Antenatal ultrasound to predict postnatal renal function in congenital lower urinary tract obstruction: systematic review of test accuracy. BJOG. 2009;116:1290-9 pubmed publisher
    ..Congenital urinary tract obstruction can lead to perinatal mortality and morbidity. Assessing antenatal ultrasound features may help identify fetuses likely to suffer complications...
  6. Słodki M, Janiak K, Szaflik K, Respondek Liberska M. Hydrothorax treated in utero and monitored by fetal echocardiography. Ginekol Pol. 2009;80:386-9 pubmed
    ..If there are no complications such as premature rupture of the membranes and preterm delivery, fetal echocardiography is a sufficient way of monitoring fetal well-being and the results of intrauterine procedures...
  7. Santore M, Roybal J, Flake A. Prenatal stem cell transplantation and gene therapy. Clin Perinatol. 2009;36:451-71, xi pubmed publisher
    ..The article also reviews the experimental data that support the capacity of IUHCT to induce donor-specific tolerance...
  8. Thayyil S, Chandrasekaran M, Chitty L, Wade A, Skordis Worrall J, Bennett Britton I, et al. Diagnostic accuracy of post-mortem magnetic resonance imaging in fetuses, children and adults: a systematic review. Eur J Radiol. 2010;75:e142-8 pubmed publisher
    ..Well designed, large, prospective studies are required to evaluate the accuracy of post-mortem MR imaging, before it can be offered as a clinical tool...
  9. Kamimoto Y, Sugiyama T, Kihira T, Zhang L, Murabayashi N, Umekawa T, et al. Transgenic mice overproducing human thioredoxin-1, an antioxidative and anti-apoptotic protein, prevents diabetic embryopathy. Diabetologia. 2010;53:2046-55 pubmed publisher
    ..Using transgenic mice that overproduce human TRX-1 (TRX-Tg mice), we examined whether oxidative stress is involved in fetal dysmorphogenesis in diabetic pregnancies...
  10. Khen Dunlop N, Fourcade L, Sauvat F, de Lambert G, Victor A, Cerf Bensussan N, et al. Surgical experimental jejunoileal atresia in rat embryo. J Pediatr Surg. 2009;44:1725-9 pubmed publisher
    ..To specify the physiopathologic feature of jejunoileal atresia, we developed an experimental surgical model in fetal rat...
  11. Elovitz M, Brown A, Breen K, Anton L, Maubert M, Burd I. Intrauterine inflammation, insufficient to induce parturition, still evokes fetal and neonatal brain injury. Int J Dev Neurosci. 2011;29:663-71 pubmed publisher
    ..Subclinical intrauterine inflammation can lead to fetal brain injury and is likely to be mechanistically associated with long term adverse outcomes for exposed offspring...
  12. Inada K, Shima T, Nakashima A, Aoki K, Ito M, Saito S. Characterization of regulatory T cells in decidua of miscarriage cases with abnormal or normal fetal chromosomal content. J Reprod Immunol. 2013;97:104-11 pubmed publisher
  13. Wang J, Liu Z, Liu H, Li N, Li S, Chen X, et al. Rapid detection of aneuploidy and unbalanced chromosomal rearrangements by subtelomeric multiplex ligation-dependent probe amplification in fetuses with congenital heart disease. Fetal Diagn Ther. 2013;34:110-5 pubmed publisher
    ..Subtelomeric MLPA may be a valuable adjunct to QF-PCR and/or conventional cytogenetics for the investigation of chromosomal abnormalities in fetuses with congenital heart disease. ..
  14. Furue A, Mochizuki J, Onishi Y, Kawano S, Kanai Y, Kemmochi M, et al. Ultrasonic findings of fetal axillary lymphangioma with intralesional hemorrhage. J Med Ultrason (2001). 2016;43:285-9 pubmed publisher
    ..Ultrasonic examination proved useful in the diagnosis of intralesional bleeding in this lymphangioma. ..
  15. Di Tommaso M, Seravalli V, Cordisco A, Consorti G, Mecacci F, Rizzello F. Comparison of five classification systems for interpreting electronic fetal monitoring in predicting neonatal status at birth. J Matern Fetal Neonatal Med. 2013;26:487-90 pubmed publisher
    ..It also showed the best trade-off between sensitivity and specificity and the lowest rate of traces considered "intermediate." ..
  16. Arata N. [Pregnancy outcomes of exposure to methimazole (POEM) study]. Nihon Rinsho. 2012;70:1976-82 pubmed
    ..We issued a joint statement with the Japan Thyroid Association about the recommendation to avoid the continuation of MMI during organogenesis period in Graves' women. The final report will be made by 2014. ..
  17. Luton D, Delezoide A, Leguy M, Gobeaux C, Vuillard E, Grange G, et al. Foetal serum but not urinary ?2-microglobulin correlates with histological injury to the kidney. Clin Biochem. 2013;46:1607-10 pubmed publisher
    ..However, elevated ?2-microglobulin levels in the urine correlated only to a decreased number of glomeruli. ..
  18. Hulthén Varli I, Kublickas M, Papadogiannakis N, Petersson K. Chorioamnionitis without foetal inflammatory response is associated with stillbirth in early preterm pregnancies. J Matern Fetal Neonatal Med. 2013;26:953-9 pubmed publisher
    ..26-3.62) and CAM without a FIR (AOR: 2.44, CI: 1.10-5.41) were associated with an elevated risk of preterm stillbirth. Histological acute CAM without a FIR is associated with a higher risk for stillbirth in early preterm pregnancies. ..
  19. Paciorkowski A, Keppler Noreuil K, Robinson L, Sullivan C, Sajan S, Christian S, et al. Deletion 16p13.11 uncovers NDE1 mutations on the non-deleted homolog and extends the spectrum of severe microcephaly to include fetal brain disruption. Am J Med Genet A. 2013;161A:1523-30 pubmed publisher
    ..Sequencing of other candidate genes in this region in patients with deletion 16p13.11 and more severe neurophenotypes may be warranted...
  20. Teunissen J, Dams A, Bruneel E. Prenatal detection of an enteric duplication cyst. Acta Chir Belg. 2013;113:355-6 pubmed
    ..We describe a case of enteric duplication cyst diagnosed prenatally and resected soon after birth. Early diagnosis and prompt surgical treatment are the best way to prevent associated morbidity. ..
  21. Kim M, Rostas S, Gabardi S. Mycophenolate fetal toxicity and risk evaluation and mitigation strategies. Am J Transplant. 2013;13:1383-9 pubmed publisher
    ..Although the impact of the MPA REMS on clinical practice is not clear, it is a step toward increasing the understanding of fetal risks with MPA products among patients and possibly practitioners. ..
  22. Jamal A, Abbasalizadeh F, Vafaei H, Marsoosi V, Eslamian L. Multicenter screening for adverse pregnancy outcomes by uterine artery Doppler in the second and third trimester of pregnancy. Med Ultrason. 2013;15:95-100 pubmed
    ..Increased uterine artery PI in second and third trimester of pregnancy is associated with an increased risk of adverse pregnancy outcomes. ..
  23. St Aubin M, Willihnganz Lawson K, Varda B, Fine M, Adejoro O, Prosen T, et al. Society for fetal urology recommendations for postnatal evaluation of prenatal hydronephrosis--will fewer voiding cystourethrograms lead to more urinary tract infections?. J Urol. 2013;190:1456-61 pubmed publisher
    ..Patients with a SFU grade of 4 progressed to surgical intervention at a faster rate than those with a grade of greater than 3. ..
  24. Freud L, Tworetzky W. Fetal interventions for congenital heart disease. Curr Opin Pediatr. 2016;28:156-62 pubmed publisher
    ..FCI is an evolving form of treatment for congenital heart disease that holds promise for select patients. Critical evaluation of both short and long-term outcomes is warranted. ..
  25. Miner J, Cao B, Govero J, Smith A, Fernandez E, Cabrera O, et al. Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise. Cell. 2016;165:1081-1091 pubmed publisher
    ..These models will facilitate the study of ZIKV pathogenesis, in utero transmission, and testing of therapies and vaccines to prevent congenital malformations. ..
  26. Zimowski J, Fidziańska E, Holding M, Zaremba J. Two mutations in one dystrophin gene. Neurol Neurochir Pol. 2013;47:131-7 pubmed
    ..3%). The phenomenon of detected non-contiguous deletions and duplications is presented together with 31 similar cases published so far. ..
  27. Moon Grady A, Morris S, Belfort M, Chmait R, Dangel J, Devlieger R, et al. International Fetal Cardiac Intervention Registry: A Worldwide Collaborative Description and Preliminary Outcomes. J Am Coll Cardiol. 2015;66:388-99 pubmed publisher
    ..We describe the contents of the IFCIR and present post-natal data to suggest potential benefit to fetal therapy among pregnancies considered for possible intervention and support proposals for additional work. ..
  28. Salomon O, Rosenberg N. Predicting risk severity and response of fetal neonatal alloimmune thrombocytopenia. Br J Haematol. 2013;162:304-12 pubmed publisher
    ..Whether those novel treatments will eventually replace the conventional high dose immunoglobulin G in women with FNAIT is yet unknown. ..
  29. Plevani C, Locatelli A, Paterlini G, Ghidini A, Tagliabue P, Pezzullo J, et al. Fetal hydronephrosis: natural history and risk factors for postnatal surgery. J Perinat Med. 2014;42:385-91 pubmed publisher
    ..Risk of unfavorable outcome increases with the degree of dilatation of the renal pelvis and the presence of urinary tract anomalies. An AP diameter ?7 mm in the third trimester warrants postnatal follow-up. ..
  30. Jaeggi E, Öhman A. Fetal and Neonatal Arrhythmias. Clin Perinatol. 2016;43:99-112 pubmed publisher
    ..Enduring bradycardia may result from sinus node dysfunction, complete heart block and nonconducted atrial bigeminy as the main arrhythmia mechanisms. The management and outcome of bradycardia depend on the underlying mechanism. ..
  31. Michel M, Schmitz R, Kiesel L, Steinhard J. Fetal myocardial peak systolic strain before and after intrauterine red blood cell transfusion--a tissue Doppler imaging study. J Perinat Med. 2012;40:545-50 pubmed publisher
    ..026; ROI 4, P=0.009). The increase in myocardial PS due to severe fetal anemia is partially normalized by IUT. In anemic fetuses, assessment of TDI fetal myocardial PS is feasible. ..
  32. Ferrazzi E, Muggiasca M, Fabbri E, Fontana P, Castoldi F, Lista G, et al. Assessment of fetal inflammatory syndrome by "classical" markers in the management of preterm labor: a possible lesson from metabolomics and system biology. J Matern Fetal Neonatal Med. 2012;25:54-61 pubmed publisher
    ..These positive findings must be interpreted with cautions given the limited number of cases considered by this study. ..
  33. Bruny J, Crombleholme T. Perinatal management of infant tumors and the promise of fetal surgery. Curr Opin Pediatr. 2013;25:31-9 pubmed publisher
    ..There are rare indications for prenatal fetal intervention. Diagnosis of a fetal tumor should prompt referral to a specialized center. Further understanding of these rare patients will require multicenter collaboration. ..
  34. Ventura W, Nazario Redondo C, Sekizawa A. Non-invasive prenatal diagnosis from the perspective of a low-resource country. Int J Gynaecol Obstet. 2013;122:270-3 pubmed publisher
    ..Since the rapid spread around the world of prenatal diagnosis based on cell-free fetal DNA, it is time to start thinking how this cutting-edge technology might influence current practice of obstetrics in low-resource countries. ..
  35. Mogos M, Rahman S, Salihu H, Salinas Miranda A, Sultan D. Association between reproductive cancer and fetal outcomes: a systematic review. Int J Gynecol Cancer. 2013;23:1171-7 pubmed publisher
  36. Seven A, Savran B, Kocak E, Tok S, Yuksel K, Gozukara I, et al. Is there a correlation between maternal serum TGF-?1 levels and fetal hydronephrosis?. J Matern Fetal Neonatal Med. 2016;29:1113-6 pubmed publisher
    ..We therefore require further studies involving larger groups with moderate or severe fetal hydronephrosis to detect the usefulness of the serum levels of TGF-?1 in pregnant women with fetal hydronephrosis. ..
  37. Kowalski T, Fraga L, Tovo Rodrigues L, Sanseverino M, Hutz M, Schuler Faccini L, et al. New Findings in eNOS gene and Thalidomide Embryopathy Suggest pre-transcriptional effect variants as susceptibility factors. Sci Rep. 2016;6:23404 pubmed publisher
    ..These results suggest variants in NOS3, with pre-transcriptional effects as susceptibility factors, influencing the risk TE development. This finding generates insight for a new approach to research that pursues a safer analogue. ..
  38. Sirotkina M, Iwarsson E, Marnerides A, Papadogiannakis N. Fetal mediastinal tumor of neuroepithelial origin in a case of missed abortion. Pediatr Dev Pathol. 2012;15:511-3 pubmed publisher
  39. Nemec S, Nemec U, Brugger P, Wadhawan I, Prayer D. Skeletal development on fetal magnetic resonance imaging. Top Magn Reson Imaging. 2011;22:101-6 pubmed publisher
  40. Kelani A, Moumouni H, Younsa H, James Didier L, Hima A, Guemou A, et al. A case of cephalomelia discovered in a baby born in Niger. Childs Nerv Syst. 2016;32:205-8 pubmed publisher
    ..This could be the so-called céphalomélie described by Isidore Geoffroy Saint-Hilaire in a duck in his famous Treatise of Teratology (1836). The cause of this malformation is still a matter for debate. ..
  41. Peiro J, Scorletti F, Sbragia L. Prenatal diagnosis of cloacal malformation. Semin Pediatr Surg. 2016;25:71-5 pubmed publisher
    ..We reviewed our experience and the literature in order to highlight the most important clues that can guide the physician in the differential diagnosis. ..
  42. Wettach C, Thomann J, Lambrigger Steiner C, Buclin T, Desmeules J, von Mandach U. Pharmacovigilance in pregnancy: adverse drug reactions associated with fetal disorders. J Perinat Med. 2013;41:301-7 pubmed
    ..The results suggest that the nervous system drug group bears an especially high risk for malformations. The most commonly identified drug exposures can help focus pharmacoepidemiologic efforts in drug-induced birth defects. ..
  43. Kaptanoglu A, Arca T, Sargon M, Kilinc K. Protective effect of dexamethasone on fetal rat skin in experimental intrauterine ischaemia/reperfusion injury. Clin Exp Dermatol. 2013;38:396-402 pubmed publisher
    ..Oedema and mitochondrial damage were less severe in the dexamethasone-treated group. Maternal treatment with dexamethasone may have a protective effect on fetal skin in cases of I/R injury. ..
  44. Tuzović L, Tang S, Miller R, Rohena L, Shahmirzadi L, Gonzalez K, et al. New Insights into the Genetics of Fetal Megacystis: ACTG2 Mutations, Encoding γ-2 Smooth Muscle Actin in Megacystis Microcolon Intestinal Hypoperistalsis Syndrome (Berdon Syndrome). Fetal Diagn Ther. 2015;38:296-306 pubmed publisher
    ..These findings have implications for the counseling of families with a diagnosis of fetal megacystis with a preserved amniotic fluid volume and associated gastrointestinal findings. ..
  45. Madu A, Olamijulo J. Pregnancy complicated by a severe form of foetal osteogenesis imperfecta in a 17-year-old primigravida: case report and overview of literature. J Matern Fetal Neonatal Med. 2013;26:703-5 pubmed publisher
    ..The diagnosis of the severe forms can be readily made but some forms of the disease are known to go unrecognised until childhood. ..
  46. Hergan B, Atar O, Poretti A, Huisman T. Serial fetal MRI for the diagnosis of Aicardi syndrome. Neuroradiol J. 2013;26:380-4 pubmed
    ..Additionally, this case emphasizes the importance of serial fetal MRI studies to more accurately delineate the progression of findings during brain development. ..
  47. Mola G, Kuk J. Operative vaginal delivery at Port Moresby General Hospital from 1977 to 2010. P N G Med J. 2011;54:174-84 pubmed
    ..5 kg and > or = 2.5 kg for the period was 11.3/1000 and 9.5/1000 respectively, and compares to a combined fresh stillbirth and early neonatal mortality rate of 8.7/1000 for assisted vaginal delivery. ..
  48. Spaggiari E, Dreux S, Czerkiewicz I, Favre R, Schmitz T, Guimiot F, et al. Fetal obstructive uropathy complicated by urinary ascites: outcome and prognostic value of fetal serum ?-2-microglobulin. Ultrasound Obstet Gynecol. 2013;41:185-9 pubmed publisher
    ..Fetal serum ?-2-microglobulin reliably predicts postnatal renal outcome in obstructive uropathy complicated by urinary ascites. Moreover, urine extravasation does not seem to protect fetal renal function. ..
  49. Picone O, Vauloup Fellous C, Cordier A, Guitton S, Senat M, Fuchs F, et al. A series of 238 cytomegalovirus primary infections during pregnancy: description and outcome. Prenat Diagn. 2013;33:751-8 pubmed publisher
    ..The rate of materno fetal transmission is linearly correlated to the gestational age at infection. No severe case of congenital infection was observed if maternal infection occurred after 14?weeks of gestation. ..
  50. Pooh R. Imaging diagnosis of congenital brain anomalies and injuries. Semin Fetal Neonatal Med. 2012;17:360-76 pubmed publisher
    ..Longitudinally and carefully evaluation of neurological short- or long-term prognosis should be required according to precise prenatal diagnosis, for proper counseling and management based on precise evidence...
  51. Barbosa J, Chow J, Benson C, Yorioka M, Bull A, Retik A, et al. Postnatal longitudinal evaluation of children diagnosed with prenatal hydronephrosis: insights in natural history and referral pattern. Prenat Diagn. 2012;32:1242-9 pubmed publisher
    ..Existing studies are flawed with biased cohorts or inconsistent follow-up. We aimed to evaluate the incidence of pathology in a large cohort of PNH and assess the biases and outcomes of this population...
  52. Zwemer L, Bianchi D. The amniotic fluid transcriptome as a guide to understanding fetal disease. Cold Spring Harb Perspect Med. 2015;5: pubmed publisher
    ..Analysis of the fetal transcriptome in normal and abnormal development has led to novel approaches for in utero prenatal treatment...
  53. Tavil B, Korkmaz A, Bayhan T, Aytac S, Unal S, Kuskonmaz B, et al. Foetal and neonatal intracranial haemorrhage in term newborn infants: Hacettepe University experience. Blood Coagul Fibrinolysis. 2016;27:163-8 pubmed publisher
    ..Furthermore, early diagnosis, close monitoring and prompt surgical interventions are significant factors to reduce disabilities. ..
  54. D Souza E, Sawant P, Nadkarni A, Gorakshakar A, Ghosh K, Colah R. Detection of fetal mutations causing hemoglobinopathies by non-invasive prenatal diagnosis from maternal plasma. J Postgrad Med. 2013;59:15-20 pubmed publisher
    ..Currently used fetal sampling procedures are invasive with some risk of miscarriage. A non-invasive approach to obtain fetal deoxyribonucleic acid (DNA) for diagnosis would eliminate this risk...
  55. Iliodromiti Z, Zygouris D, Sifakis S, Pappa K, Tsikouras P, Salakos N, et al. Acute lung injury in preterm fetuses and neonates: mechanisms and molecular pathways. J Matern Fetal Neonatal Med. 2013;26:1696-704 pubmed publisher
    ..Future research should concentrate on the pathophysiology of ALI in preterm neonates and ?n possible pharmaceutical interventions targeting prevention and/or resolution of ALI...
  56. Sviggum H, Kodali B. Maternal anesthesia for fetal surgery. Clin Perinatol. 2013;40:413-27 pubmed publisher
    ..Discussion includes general principles common to all fetal surgeries as well as specifics pertaining to open fetal surgery, minimally invasive fetal surgery, and ex utero intrapartum therapy (EXIT) procedures. ..
  57. Ocak Z, Ozlu T, Vural M. Anal atresia, abnormal genitalia, and absent thumb: congenital malformations associated with mosaic ring chromosome 13. Genet Couns. 2013;24:157-60 pubmed
    ..We report a case with mosaic ring chromosome 13 whose prenatal ultrasound revealed bilateral ventriculomegaly. Anal atresia, unidentifiable external genitalia, and an absent thumb were observed in the postmortem examination...
  58. Cassar N, Grima A, Ellul G, Schembri Wismayer P, Calleja Agius J. Screening for thyroid disease in pregnancy: a review. Minerva Ginecol. 2013;65:471-84 pubmed
    ..The review then discusses the current major arguments for and against screening, as well as recommendations and proposed alternatives. ..
  59. Varavithya V, Phongkitkarun S, Raungrongmorakot K, Rujiwetpongstorn J, Chittacharoen A. The influence of MR imaging on changes in patient counseling in obstetric patients with suspected fetal anomalies by ultrasound. J Med Assoc Thai. 2013;96:839-48 pubmed
    ..To determine the frequency of additional information provided by magnetic resonance (MR) imaging in supplement to ultrasound (US) in patients with fetal anomaly and to determine the influence of MR imaging findings on patient counseling...
  60. . Practice bulletin no. 151: Cytomegalovirus, parvovirus B19, varicella zoster, and toxoplasmosis in pregnancy. Obstet Gynecol. 2015;125:1510-25 pubmed publisher
  61. Yamasaki M, Nonaka M, Bamba Y, Teramoto C, Ban C, Pooh R. Diagnosis, treatment, and long-term outcomes of fetal hydrocephalus. Semin Fetal Neonatal Med. 2012;17:330-5 pubmed publisher
  62. Hannon T, Tennant P, Rankin J, Robson S. Epidemiology, natural history, progression, and postnatal outcome of severe fetal ventriculomegaly. Obstet Gynecol. 2012;120:1345-53 pubmed publisher
    ..To estimate the prevalence, associated anomalies, progression, and clinical outcome in fetuses prenatally diagnosed with severe ventriculomegaly...
  63. Reed D, Stiller R. Challenges in the diagnosis and treatment of congenital syphilis. Conn Med. 2012;76:397-400 pubmed
    ..This report demonstrates a number of challenges to the clinician in the effective and timely diagnosis and treatment of syphilis in pregnancy...
  64. Wang F, Reece E, Yang P. Superoxide dismutase 1 overexpression in mice abolishes maternal diabetes-induced endoplasmic reticulum stress in diabetic embryopathy. Am J Obstet Gynecol. 2013;209:345.e1-7 pubmed publisher
    ..Both oxidative stress and endoplasmic reticulum stress (ER stress) are causal events in diabetic embryopathy. We tested whether oxidative stress causes ER stress...
  65. Macardle C, Kunisaki S. Management of perinatal lung malformations. Minerva Ginecol. 2015;67:81-94 pubmed
    ..Other complications, such as recurrent pneumonia, pneumothorax, and cancer, are indications for lung resection on an elective basis. In the vast majority of cases, the overall prognosis remains excellent. ..
  66. Stefanovic V. Fetomaternal hemorrhage complicated pregnancy: risks, identification, and management. Curr Opin Obstet Gynecol. 2016;28:86-94 pubmed publisher
    ..In addition, a simplified flow chart for the antenatal management of suspected FMH is proposed...
  67. Scher M. Peripartum consultations expand the role of the fetal/neonatal neurologist. Pediatr Neurol. 2012;47:411-8 pubmed publisher
    ..Appropriate choices of preventive, rescue, and repair neuroprotective interventions must consider both the timing and etiologies of encephalopathies in the context of maternal, fetal, placental, and neonatal diseases...
  68. Imam K. Gestational diabetes mellitus. Adv Exp Med Biol. 2012;771:24-34 pubmed
    ..Because body fat and diet contribute to the risk of gestational diabetes mellitus, patients who lose weight before pregnancy and follow an appropriate diet may lower their risk of gestational diabetes mellitus...
  69. Nijagal A, MacKenzie T. Clinical implications of maternal-fetal cellular trafficking. Semin Pediatr Surg. 2013;22:62-5 pubmed publisher
    ..An improved understanding of cellular trafficking during pregnancy will lead to progress in multiple fields including autoimmunity, transplantation, and fetal surgery...
  70. Turner C, Pennington E, Gray F, Ahmed A, Teng Y, Fauza D. Intra-amniotic delivery of amniotic-derived neural stem cells in a syngeneic model of spina bifida. Fetal Diagn Ther. 2013;34:38-43 pubmed publisher
    ..Neural stem cells (NSCs) may promote spinal cord repair in fetuses with experimental spina bifida. We sought to determine the fate of amniotic-derived NSCs (aNSCs) after simple intra-amniotic injection in a syngeneic model of spina bifida...
  71. Lim J, Whittle W, Lee Y, Ryan G, Van Mieghem T. Early anatomy ultrasound in women at increased risk of fetal anomalies. Prenat Diagn. 2013;33:863-8 pubmed publisher
    ..This study was designed to assess the accuracy of ultrasound anatomy screening before 17 weeks gestation in a population at high risk of fetal anomalies...
  72. Inchingolo R, Maresca G, Cacaci S, Ausili E, Paolucci V, Bonomo L, et al. Post-natal ultrasound morpho-dynamic evaluation of mild fetal hydronephrosis: a new management. Eur Rev Med Pharmacol Sci. 2013;17:2232-9 pubmed
    ..Fetal hydronephrosis is the most common anomaly detected on antenatal ultrasound examination, affecting 1-5% pregnancies...
  73. Clothier K, Anderson M. Evaluation of bovine abortion cases and tissue suitability for identification of infectious agents in California diagnostic laboratory cases from 2007 to 2012. Theriogenology. 2016;85:933-938 pubmed publisher
    ..This review highlights the need for submission of critical samples including abomasal contents, lymphoid tissues (thymus, spleen, and lymph nodes), and brain to maximize the diagnosticians' ability to identify causes of abortion. ..
  74. Sorano S, Goto M, Matsuoka S, Tohyama A, Yamamoto H, Nakamura S, et al. Chorioamnionitis caused by Staphylococcus aureus with intact membranes in a term pregnancy: A case of maternal and fetal septic shock. J Infect Chemother. 2016;22:261-4 pubmed publisher
    ..Bacterial spread in the absence of membrane rupture and the presence of bacteremia suggests hematogenous, rather than ascending, etiology of S. aureus chorioamnionitis. ..
  75. Srichomkwun P, Anselmo J, Liao X, Hönes G, Moeller L, Alonso Sampedro M, et al. Fetal Exposure to High Maternal Thyroid Hormone Levels Causes Central Resistance to Thyroid Hormone in Adult Humans and Mice. J Clin Endocrinol Metab. 2017;102:3234-3240 pubmed publisher
    ..Fetuses exposed to the high thyroid hormone (TH) levels of mothers with resistance to thyroid hormone beta (RTH-?), due to mutations in the THRB gene, have low birth weight and suppressed TSH...
  76. Wiggins D, Strasburger J, Gotteiner N, Cuneo B, Wakai R. Magnetophysiologic and echocardiographic comparison of blocked atrial bigeminy and 2:1 atrioventricular block in the fetus. Heart Rhythm. 2013;10:1192-8 pubmed publisher
    ..Since the prognosis and clinical management of these rhythms are different, an accurate diagnosis is essential...
  77. Matsuda Y, Ogawa M, Konno J, Mitani M, Matsui H. Prediction of fetal acidemia in placental abruption. BMC Pregnancy Childbirth. 2013;13:156 pubmed publisher
    ..To determine the major predictive factors for fetal acidemia in placental abruption...
  78. Kuo T, Sun Y, Hong N, Tsai H, Lin C, Lin M, et al. Multidisciplinary examination for prenatal diagnosis of posterior cervical teratoma in early second trimester. Taiwan J Obstet Gynecol. 2013;52:270-2 pubmed publisher
    ..In this report, we present a case of congenital posterior cervical teratoma diagnosed by a two-dimensional (2D) ultrasound in the early second trimester...
  79. Morris R, Malin G, Quinlan Jones E, Middleton L, Hemming K, Burke D, et al. Percutaneous vesicoamniotic shunting versus conservative management for fetal lower urinary tract obstruction (PLUTO): a randomised trial. Lancet. 2013;382:1496-506 pubmed publisher
    ..Fetal lower urinary tract obstruction (LUTO) is associated with high perinatal and long-term childhood mortality and morbidity. We aimed to assess the effectiveness of vesicoamniotic shunting for treatment of LUTO...
  80. Cohen A, Couto J, Cummings J, Johnson A, Joseph G, Kaufman B, et al. Position statement on fetal myelomeningocele repair. Am J Obstet Gynecol. 2014;210:107-11 pubmed publisher
    ..The decision was made to develop the optimal practice criteria presented in this document for the purpose of medical and surgical leadership. These criteria are not intended to be used for legal or regulatory purposes. ..
  81. Tan R, Lee J, Biswas A, Amutha C. Ascites, anemia and (intestinal) atresia. J Perinatol. 2014;34:78-80 pubmed publisher
    ..Early treatment in our patient with intrauterine blood transfusion may have altered the natural history of her condition, allowing pregnancy to progress to term with a subsequent improved outcome. ..
  82. Statile C, Cnota J, Gomien S, Divanovic A, Crombleholme T, Michelfelder E. Estimated cardiac output and cardiovascular profile score in fetuses with high cardiac output lesions. Ultrasound Obstet Gynecol. 2013;41:54-8 pubmed publisher
    ..We aimed to test the hypothesis that elevated combined cardiac output (CCO) in fetuses with high output lesions may be associated with worsening cardiovascular status, as evidenced by a lower CVPS...
  83. Vianna F, Schuler Faccini L, Leite J, de Sousa S, da Costa L, Dias M, et al. Recognition of the phenotype of thalidomide embryopathy in countries endemic for leprosy: new cases and review of the main dysmorphological findings. Clin Dysmorphol. 2013;22:59-63 pubmed publisher
    ..Here, we present two new cases of thalidomide embryopathy identified in 2011 and review the major clinical findings in the literature that can aid the identification of the embryopathy...
  84. Cîrstoiu M, Munteanu O, Bodean O, Cirstoiu C. A rare case of fetal spondylocostal dysostosis - prenatal diagnosis and perinatal care in a patient with multiple large leiomyomas. J Med Life. 2013;6:93-6 pubmed
    ..The SCD can have a favorable evolution with the appropriate perinatal and postpartum care...
  85. Hauck A, da Cruz E, Jaggers J, Jone P. Tricuspid atresia associated with truncus arteriosus versus aortopulmonary window: combining fetal and postnatal echocardiography to make the diagnosis. Echocardiography. 2013;30:E336-9 pubmed publisher
    ..The patient underwent successful palliation consisting of APW repair, atrial septectomy and a 3.5 mm modified Blalock-Taussig shunt, followed by a bidirectional cavopulmonary connection. ..
  86. Gottschalk I, Stressig R, Ritgen J, Herberg U, Breuer J, Vorndamme A, et al. Extracardiac anomalies in prenatally diagnosed heterotaxy syndrome. Ultrasound Obstet Gynecol. 2016;47:443-9 pubmed publisher
    ..Copyright © 2015 ISUOG. Published by John Wiley & Sons Ltd. ..
  87. Batra C, Gupta V, Gupta N, Menon P. Fetal Hyperthyroidism: Intrauterine Treatment with Carbimazole in Two Siblings. Indian J Pediatr. 2015;82:962-4 pubmed publisher
    ..Fetal tachycardia was noted in the fifth pregnancy as well and she was treated with carbimazole and thyroxine. She delivered a male baby at 37 wk. He developed neonatal hypothyroidism on day 8 which was controlled with thyroxine. ..
  88. Malinowski W, Cwiek D. Fetus papyraceus in dichorionic diamniotic twin pregnancy: a case report. Ginekol Pol. 2012;83:858-61 pubmed
    ..The actual rate of multiple pregnancies is significantly larger than that observed during labor due to the fact that in the course of pregnancy intrauterine death of one or more fetuses may occur...
  89. Chuchracki M, Szczepaniak A, Sedziak A, Ziółkowska K, Opala T. [Frequency of prevalence of Turner syndrome in fetuses of patients referred to genetic amniocentesis in 2007-2011]. Przegl Lek. 2012;69:1011-4 pubmed
    ..In case of indications such as genetic defects in the family, incorrect result of triple test are not confirmed by Turner syndrome...
  90. Godino L, Turchetti D, Skirton H. A systematic review of factors influencing uptake of invasive fetal genetic testing by pregnant women of advanced maternal age. Midwifery. 2013;29:1235-43 pubmed publisher
    ..This type of research will help to equip midwives and other professionals caring for women during pregnancy to ensure that women are supported to make the choices that are appropriate for them and their families. ..
  91. McBrien A, Howley L, Yamamoto Y, Hutchinson D, Hirose A, Sekar P, et al. Changes in fetal cardiac axis between 8 and 15?weeks' gestation. Ultrasound Obstet Gynecol. 2013;42:653-8 pubmed publisher
    ..To document changes in the normal embryonic/fetal cardiac axis in the late first and early second trimesters of pregnancy...