nephritis

Summary

Summary: Inflammation of any part of the KIDNEY.

Top Publications

  1. Ernandez T, Mayadas T. Immunoregulatory role of TNFalpha in inflammatory kidney diseases. Kidney Int. 2009;76:262-76 pubmed publisher
    ..alpha (TNFalpha), a pleiotropic cytokine, plays important inflammatory roles in renal diseases such as lupus nephritis, anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis and renal allograft rejection...
  2. Vilaysane A, Chun J, Seamone M, Wang W, Chin R, Hirota S, et al. The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. J Am Soc Nephrol. 2010;21:1732-44 pubmed publisher
    ..Taken together, these results strongly support a role for NLRP3 in renal injury and identify the inflammasome as a possible therapeutic target in the treatment of patients with progressive CKD...
  3. Kawasaki Y. The pathogenesis and treatment of pediatric Henoch-Schönlein purpura nephritis. Clin Exp Nephrol. 2011;15:648-657 pubmed publisher
    ..Thus, it is important to clarify the onset mechanism of Henoch-Schönlein purpura nephritis (HSPN) and to identify the most appropriate treatment. We herein review the pathogenesis and treatment of HSPN...
  4. Kang K, Kim D, Jung Y, Lee A, Lee S, Lee S, et al. Alpha-lipoic acid attenuates cisplatin-induced acute kidney injury in mice by suppressing renal inflammation. Nephrol Dial Transplant. 2009;24:3012-20 pubmed publisher
    ..The goals of this study were to investigate the anti-inflammatory effects of alpha-LA during cisplatin-induced renal injury and to examine the mechanisms of protection...
  5. Pedchenko V, Bondar O, Fogo A, Vanacore R, Voziyan P, Kitching A, et al. Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis. N Engl J Med. 2010;363:343-54 pubmed publisher
    ..Alport's post-transplantation nephritis, which is mediated by alloantibodies against the GBM, occurs after kidney transplantation in some patients with ..
  6. Anders H. Toll-like receptors and danger signaling in kidney injury. J Am Soc Nephrol. 2010;21:1270-4 pubmed publisher
    ..The evolving concept of danger signaling provides a general mechanism for kidney injury...
  7. Du Y, Hou L, Zhao C, Han M, Wu Y. Treatment of children with Henoch-Schönlein purpura nephritis with mycophenolate mofetil. Pediatr Nephrol. 2012;27:765-71 pubmed publisher
    Henoch-Schönlein purpura (HSP) can progress to Henoch-Schönlein purpura nephritis (HSPN), and the most effective management remains unclear...
  8. Kasagi S, Kawano S, Okazaki T, Honjo T, Morinobu A, Hatachi S, et al. Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupus-like nephritis of NZB/W F1 mice. J Immunol. 2010;184:2337-47 pubmed publisher
    ..In this study, we used NZB/W F1 mice, a model of lupus-like nephritis, to examine the function of PD-1 and its ligands...
  9. Lu Y, Liu X, Shi S, Su H, Bai X, Cai G, et al. Bioinformatics analysis of proteomic profiles during the process of anti-Thy1 nephritis. Mol Cell Proteomics. 2012;11:M111.008755 pubmed publisher
    Anti-Thy1 nephritis is a well-established experimental mesangial proliferative nephritis model. Exploring the molecular mechanisms of pathophysiology in anti-Thy1 nephritis may elucidate the pathogeneses of mesangial proliferation...

Scientific Experts

More Information

Publications62

  1. Mack M, Rosenkranz A. Basophils and mast cells in renal injury. Kidney Int. 2009;76:1142-7 pubmed publisher
    ..In this review, we describe how mast cells and basophils affect immune responses and discuss implications for renal diseases and transplant rejection...
  2. Soylemezoglu O, Ozkaya O, Ozen S, Bakkaloglu A, Dusunsel R, Peru H, et al. Henoch-Schönlein nephritis: a nationwide study. Nephron Clin Pract. 2009;112:c199-204 pubmed publisher
    The aim of this retrospective study was to evaluate the presentation, clinical and pathological manifestations and outcome of the Henoch-Schönlein purpura (HSP) nephritis in children.
  3. Yang W, Zhao M, Hirankarn N, Lau C, Mok C, Chan T, et al. ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai. Hum Mol Genet. 2009;18:2063-70 pubmed publisher
    ..Subphenotype stratification analyses showed significantly more involvement of the gene in patients with renal nephritis and neurological disorders...
  4. Skaggs B, Lourenço E, Hahn B. Oral administration of different forms of a tolerogenic peptide to define the preparations and doses that delay anti-DNA antibody production and nephritis and prolong survival in SLE-prone mice. Lupus. 2011;20:912-20 pubmed publisher
    ..Induction of oral tolerance using modified pCons peptides could lead to a novel targeted therapy for human SLE...
  5. Du Y, An S, Liu L, Li L, Zhou X, Mason R, et al. Serial non-invasive monitoring of renal disease following immune-mediated injury using near-infrared optical imaging. PLoS ONE. 2012;7:e43941 pubmed publisher
    ..The LI-COR IRDye® 800CW RGD optical probe (RGD probe) is a NIR fluorophore, that can target integrin alpha v beta 3 (?(v)?(3)) in tissues...
  6. Oh H, Ahn S, Yoo D, Kim S, Shin D, Lee M, et al. Clinical outcomes, when matched at presentation, do not vary between adult-onset Henöch-Schönlein purpura nephritis and IgA nephropathy. Kidney Int. 2012;82:1304-12 pubmed publisher
    Henöch-Schönlein purpura nephritis (HSPN) is considered a systemic form of immunoglobulin A nephropathy (IgAN)...
  7. Lui S, Tsang R, Chan K, Zhang F, Tam S, Yung S, et al. Rapamycin attenuates the severity of established nephritis in lupus-prone NZB/W F1 mice. Nephrol Dial Transplant. 2008;23:2768-76 pubmed publisher
    ..The aim of this study was to determine the effect of rapamycin on the severity of established nephritis in lupus-prone New Zealand Black/White F(1) (NZB/W F(1)) mice.
  8. Steinmetz O, Velden J, Kneissler U, Marx M, Klein A, Helmchen U, et al. Analysis and classification of B-cell infiltrates in lupus and ANCA-associated nephritis. Kidney Int. 2008;74:448-57 pubmed publisher
    ..Therefore we characterized intrarenal lymphoid clusters of 32 patients diagnosed with lupus nephritis and 16 with ANCA associated nephritis...
  9. Hamilton J. Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol. 2008;8:533-44 pubmed publisher
    ..Here, I describe these biological features, discuss the probable specific outcomes of targeting CSFs in vivo and highlight outstanding questions that need to be addressed...
  10. Fletcher C, Groom J, Woehl B, Leung H, MacKay C, Mackay F. Development of autoimmune nephritis in genetically asplenic and splenectomized BAFF transgenic mice. J Autoimmun. 2011;36:125-34 pubmed publisher
    ..To ascertain the relevance of B1 and MZ-like B cells in the development of nephritis in BAFF Tg mice, we generated genetically asplenic as well as splenectomized BAFF Tg animals...
  11. Jauhola O, Ronkainen J, Autio Harmainen H, Koskimies O, Ala Houhala M, Arikoski P, et al. Cyclosporine A vs. methylprednisolone for Henoch-Schönlein nephritis: a randomized trial. Pediatr Nephrol. 2011;26:2159-66 pubmed publisher
    Knowledge about how to treat severe Henoch-Schönlein nephritis (HSN) is scarce. The aim of our study is to compare cyclosporine A (CyA) and methylprednisolone pulses (MP) in the treatment of severe HSN...
  12. Qiu W, Zhang Y, Liu X, Zhou J, Li Y, Zhou Y, et al. Sublytic C5b-9 complexes induce proliferative changes of glomerular mesangial cells in rat Thy-1 nephritis through TRAF6-mediated PI3K-dependent Akt1 activation. J Pathol. 2012;226:619-32 pubmed publisher
    The proliferation of glomerular mesangial cells (GMCs) and secretion of extracellular matrix (ECM) in rat Thy-1 nephritis (Thy-1N), resembling human mesangioproliferative glomerulonephritis (MsPGN), have been studied for many years, but ..
  13. Tan X, Wen X, Liu Y. Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kappaB signaling. J Am Soc Nephrol. 2008;19:1741-52 pubmed publisher
    ..These results suggest that paricalcitol inhibits renal inflammatory infiltration and RANTES expression by promoting VDR-mediated sequestration of NF-kappaB signaling...
  14. Carlucci F, Cook H, Garg A, Pepys M, Botto M. Lack of effect of a single injection of human C-reactive protein on murine lupus or nephrotoxic nephritis. Arthritis Rheum. 2010;62:245-9 pubmed publisher
    ..of spontaneous lupus, as well as the rapid-onset immune complex disease induced in the accelerated nephrotoxic nephritis (ANTN) model...
  15. Van Moerkercke W, Verhamme M, Meeus G, Oyen R, Steenbergen W. A case of IgG4-related sclerosing disease with retroperitoneal fibrosis, autoimmune pancreatitis and bilateral focal nephritis. Pancreas. 2009;38:825-32 pubmed publisher
    ..IgG4-related sclerosing disease with involvement of the pancreas, retroperitoneal fibrosis, and bilateral focal nephritis. To our knowledge, this is the first report on these 3 clinical entities occurring in the same patient...
  16. Moura C, Lima I, Barbosa L, Athanazio D, Reis E, Reis M, et al. Anti-C1q antibodies: association with nephritis and disease activity in systemic lupus erythematosus. J Clin Lab Anal. 2009;23:19-23 pubmed publisher
    Anti-C1q antibodies have been described in systemic lupus erythematosus (SLE) as well as in other connective tissue diseases. They have been considered as a marker for disease activity and presence of nephritis.
  17. Santos M, Fernandes D, Capela S, da Silva J, Fonseca J. Interleukin-6 promoter polymorphism -174 G/C is associated with nephritis in Portuguese Caucasian systemic lupus erythematosus patients. Clin Rheumatol. 2011;30:409-13 pubmed publisher
    ..The IL-6 gene promoter polymorphism at position -174 does not contribute to SLE susceptibility in Portuguese Caucasian patients but may predispose to specific manifestations of the disease...
  18. Ito K, Yamada K, Mizushima I, Aizu M, Fujii H, Mizutomi K, et al. Henoch-Schönlein purpura nephritis in a patient with IgG4-related disease: a possible association. Clin Nephrol. 2013;79:246-52 pubmed publisher
    We report a case of Henoch- Schönlein purpura nephritis (HSPN) associated with tubulointerstitial nephritis (TIN) and chronic sclerosing sialoadenitis...
  19. Yuan F, Nelson R, Tabor D, Zhang Y, Akhter M, Gould K, et al. Dexamethasone prodrug treatment prevents nephritis in lupus-prone (NZB × NZW)F1 mice without causing systemic side effects. Arthritis Rheum. 2012;64:4029-39 pubmed publisher
    To evaluate the potentially improved therapeutic efficacy and safety of nephrotropic macromolecular prodrugs of glucocorticoids (GCs) for the treatment of lupus nephritis.
  20. Kosugi T, Nakayama T, Heinig M, Zhang L, Yuzawa Y, Sanchez Lozada L, et al. Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice. Am J Physiol Renal Physiol. 2009;297:F481-8 pubmed publisher
    ..In conclusion, hyperuricemia has a pathogenic role in the mild tubulointerstitial injury associated with diabetic nephropathy but not glomerular damage in db/db mice. Lowering uric acid may reduce tubulointerstitial injury in diabetes...
  21. Beres S, Sesso R, Pinto S, Hoe N, Porcella S, Deleo F, et al. Genome sequence of a Lancefield group C Streptococcus zooepidemicus strain causing epidemic nephritis: new information about an old disease. PLoS ONE. 2008;3:e3026 pubmed publisher
    ..zooepidemicus strain MGCS10565, a group C organism that caused a very large and unusually severe epidemic of nephritis in Brazil. The genome is a circular chromosome of 2,024,171 bp...
  22. Park J, Won S, Shin J, Yim H, Pai K. Cyclosporin A therapy for Henoch-Schönlein nephritis with nephrotic-range proteinuria. Pediatr Nephrol. 2011;26:411-7 pubmed publisher
    To evaluate the therapeutic role of cyclosporin A (CyA) for the treatment of Henoch-Schönlein nephritis (HSN), 29 patients (18 boys, 11 girls) with nephrotic-range proteinuria were analyzed retrospectively. Mean age was 8...
  23. Meyer Schwesinger C, Dehde S, Sachs M, Mathey S, Arefi K, Gatzemeier S, et al. Rho-kinase inhibition prevents proteinuria in immune-complex-mediated antipodocyte nephritis. Am J Physiol Renal Physiol. 2012;303:F1015-25 pubmed publisher
    ..we have developed a new experimental model of immune-mediated podocyte injury in mice, the antipodocyte nephritis (APN). Podocytes were targeted with a polyclonal antipodocyte antibody causing massive proteinuria around day 10...
  24. Nakamura K, Tabata Y. A new fluorescent imaging of renal inflammation with RCP. J Control Release. 2010;148:351-8 pubmed publisher
    ..After intravenous administration of R-Gel labeled by Cy7 of a fluorescent dye to three animal models of nephritis mousse, interstitial nephritis (by using UUO model mice), glomerulonephritis (HIGA mice), and ischemia-..
  25. Wakaki H, Ishikura K, Hataya H, Hamasaki Y, Sakai T, Yata N, et al. Henoch-Schönlein purpura nephritis with nephrotic state in children: predictors of poor outcomes. Pediatr Nephrol. 2011;26:921-5 pubmed publisher
    b>Nephritis develops in 18-81% of Henoch-Schönlein purpura patients, and the long-term outcomes of this nephritis show great variation. A nephrotic state at disease onset has been proposed as a predictor of poor renal outcomes...
  26. Cheng C, Tsau Y, Kuo C, Su L, Lin T. Comparison of extended virulence genotypes for bacteria isolated from pediatric patients with urosepsis, acute pyelonephritis, and acute lobar nephronia. Pediatr Infect Dis J. 2010;29:736-40 pubmed publisher
    ..This study was conducted to explore and differentiate bacterial virulence factors associated with urosepsis and 2 other severe parenchymal infections, acute pyelonephritis (APN) and acute lobar nephronia (ALN), in pediatric patients...
  27. Shao W, Zhen Y, Rosenbaum J, Eisenberg R, McGaha T, Birkenbach M, et al. A protective role of Mer receptor tyrosine kinase in nephrotoxic serum-induced nephritis. Clin Immunol. 2010;136:236-44 pubmed publisher
    ..Mer thus has a critical role in attenuating renal inflammation, both as a receptor for apoptotic cells and as a molecule that downregulates inflammation...
  28. Pawar R, Pitashny M, Gindea S, Tieng A, Levine B, Goilav B, et al. Neutrophil gelatinase-associated lipocalin is instrumental in the pathogenesis of antibody-mediated nephritis in mice. Arthritis Rheum. 2012;64:1620-31 pubmed publisher
    The mechanism by which anti-DNA antibodies mediate lupus nephritis has yet to be conclusively determined...
  29. Pelletier E, Ogale S, Yu E, Brunetta P, Garg J. Economic outcomes in patients diagnosed with systemic lupus erythematosus with versus without nephritis: results from an analysis of data from a US claims database. Clin Ther. 2009;31:2653-64 pubmed publisher
    Based on a literature search, there are limited data on the economic burden of systemic lupus erythematosus (SLE), particularly in patients with lupus nephritis.
  30. Otten M, Groeneveld T, Flierman R, Rastaldi M, Trouw L, Faber Krol M, et al. Both complement and IgG fc receptors are required for development of attenuated antiglomerular basement membrane nephritis in mice. J Immunol. 2009;183:3980-8 pubmed publisher
  31. Crowley S, Vasievich M, Ruiz P, Gould S, Parsons K, Pazmino A, et al. Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis. J Clin Invest. 2009;119:943-53 pubmed publisher
    ..Since AT1A-deficient lpr mice had low blood pressure, these findings suggest that activation of type 1 angiotensin receptors in the glomerulus is sufficient to accelerate renal injury and inflammation in the absence of hypertension...
  32. Zaffanello M, Fanos V. Treatment-based literature of Henoch-Schönlein purpura nephritis in childhood. Pediatr Nephrol. 2009;24:1901-11 pubmed publisher
    ..of identifying an improved therapeutic protocol for use in the treatment of childhood Henoch-Schönlein purpura nephritis, primarily due to the unpredictable success shown to date in improving long-term renal outcome...
  33. Neubert K, Meister S, Moser K, Weisel F, Maseda D, Amann K, et al. The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis. Nat Med. 2008;14:748-55 pubmed publisher
    ..Hence, the elimination of autoreactive plasma cells by proteasome inhibitors might represent a new treatment strategy for antibody-mediated diseases...
  34. Cai M, Wu J, Mao C, Ren J, Li P, Li X, et al. A Lectin-EGF antibody promotes regulatory T cells and attenuates nephrotoxic nephritis via DC-SIGN on dendritic cells. J Transl Med. 2013;11:103 pubmed publisher
    ..Under certain conditions, DC-SIGN signalling may result in inhibition of DC maturation, by promoting regulatory T cell (Treg) function and affecting Th1/Th2 bias...
  35. Tanaka M, Seki G, Ishizawa K, Hirahashi J, Miura K, Sekine T, et al. Resolution of Henoch-Schönlein purpura nephritis after acquired IgA deficiency. Pediatr Nephrol. 2010;25:2355-8 pubmed publisher
    We report a case of Henoch-Schönlein purpura nephritis (HSPN) with acquired IgA deficiency due to parvovirus B19 infection...
  36. Wnuk M, Hlushchuk R, Tuffin G, Huynh Do U, Djonov V. The effects of PTK787/ZK222584, an inhibitor of VEGFR and PDGFR? pathways, on intussusceptive angiogenesis and glomerular recovery from Thy1.1 nephritis. Am J Pathol. 2011;178:1899-912 pubmed publisher
    ..Glomerular healing by intussusception was examined in a particular setting of Thy1.1 nephritis, where the lysis of mesangial cells results in an initial collapse and successive rebuilding of glomerular ..
  37. Xia Y, Mao J, Chen Y, Wang D, Cao L, Yao S, et al. Clinical outcomes in children with Henoch-Schönlein purpura nephritis grade IIIa or IIIb. Pediatr Nephrol. 2011;26:1083-8 pubmed publisher
    ..The incidence of HSP nephritis (HSPN) among HSP patients has been reported to be 15-62%. Even so, what constitutes severe HSPN is controversial...
  38. Farres M, Al Zifzaf D, Aly A, Abd Raboh N. OX40/OX40L in systemic lupus erythematosus: association with disease activity and lupus nephritis. Ann Saudi Med. 2011;31:29-34 pubmed publisher
    OX40-OX40L interaction is implicated in the pathogenesis of systemic lupus erythematosus (SLE). We evaluated the role of OX40/OX40L as markers of disease activity and nephritis in SLE patients.
  39. Ninchoji T, Kaito H, Nozu K, Hashimura Y, Kanda K, Kamioka I, et al. Treatment strategies for Henoch-Schönlein purpura nephritis by histological and clinical severity. Pediatr Nephrol. 2011;26:563-9 pubmed publisher
    The management of Henoch-Schönlein purpura nephritis (HSPN) is controversial...
  40. Mottaghi P, Ashtari F, Karimzadeh H, Seidbonakdar Z, Karimifar M, Salesi M. Devic's syndrome concomitant with nephritis in a young woman. Clin Rheumatol. 2009;28:1239-40 pubmed publisher
  41. Oyama Y, Hashiguchi T, Taniguchi N, Tancharoen S, Uchimura T, Biswas K, et al. High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy. Lab Invest. 2010;90:853-66 pubmed publisher
    Granulomatous nephritis can be triggered by diverse factors and results in kidney failure. However, despite accumulating data about granulomatous inflammation, pathogenetic mechanisms in nephritis remain unclear...
  42. Schroll A, Eller K, Huber J, Theurl I, Wolf A, Weiss G, et al. Tim3 is upregulated and protective in nephrotoxic serum nephritis. Am J Pathol. 2010;176:1716-24 pubmed publisher
    ..diseases, we investigated whether Tim3 is involved in the pathogenesis of the T(H)-1-dependent nephrotoxic nephritis (NTS)...
  43. Eller K, Weber T, Pruenster M, Wolf A, Mayer G, Rosenkranz A, et al. CCR7 deficiency exacerbates injury in acute nephritis due to aberrant localization of regulatory T cells. J Am Soc Nephrol. 2010;21:42-52 pubmed publisher
    ..T cells mediate the pathogenesis of experimental accelerated nephrotoxic serum nephritis (NTS), including its suppression by regulatory T cells (Tregs), but the contribution of CCR7 to this disease is ..
  44. Davin J. Henoch-Schonlein purpura nephritis: pathophysiology, treatment, and future strategy. Clin J Am Soc Nephrol. 2011;6:679-89 pubmed publisher
    Henoch-Schönlein purpura nephritis is a rare kidney disease leading to chronic kidney disease in a non-negligible percentage of patients...
  45. Ren P, Han F, Chen L, Xu Y, Wang Y, Chen J. The combination of mycophenolate mofetil with corticosteroids induces remission of Henoch-Schönlein purpura nephritis. Am J Nephrol. 2012;36:271-7 pubmed publisher
    Henoch-Schönlein purpura (HSP) is a form of systemic vasculitis that can progress to Henoch-Schönlein purpura nephritis (HSPN), and the most effective treatment remains controversial...
  46. Bogdanovic R. Henoch-Schönlein purpura nephritis in children: risk factors, prevention and treatment. Acta Paediatr. 2009;98:1882-9 pubmed publisher
    To identify risk factors for a child with Henoch-Schönlein purpura (HSP) either to develop nephritis (HSPN) or to contract progressive course and to obtain the currently available evidence on the efficacy of treatment options in both ..
  47. Qiu W, Che N, Feng X, Xia M, Wang H, Zhao D, et al. Apoptosis of glomerular mesangial cells induced by sublytic C5b-9 complexes in rats with Thy-1 nephritis is dependent on Gadd45 gamma upregulation. Eur J Immunol. 2009;39:3251-66 pubmed publisher
    ..cell apoptosis, but the mechanism of sublytic C5b-9-mediated glomerular mesangial cell (GMC) apoptosis in Thy-1 nephritis (Thy-1N) remains largely unclear...
  48. Radhakrishnan N, Yadav S, Sachdeva A, Pruthi P, Sawhney S, Piplani T, et al. Human heme oxygenase-1 deficiency presenting with hemolysis, nephritis, and asplenia. J Pediatr Hematol Oncol. 2011;33:74-8 pubmed publisher
    ..report another case of human HO-1 deficiency in a young girl with congenital asplenia, who presented with severe hemolysis, inflammation, nephritis, which was refractory to therapy with corticosteroids, cyclophosphamide, and rituximab.
  49. Eller K, Wolf D, Huber J, Metz M, Mayer G, McKenzie A, et al. IL-9 production by regulatory T cells recruits mast cells that are essential for regulatory T cell-induced immune suppression. J Immunol. 2011;186:83-91 pubmed publisher
    ..To investigate a possible interaction, we used the Th1- and Th17-dependent model of nephrotoxic serum nephritis (NTS), in which both MCs and Tregs have been shown to play a protective role...
  50. Clarke H, Kocher H, Khwaja A, Kloog Y, Cook H, Hendry B. Ras antagonist farnesylthiosalicylic acid (FTS) reduces glomerular cellular proliferation and macrophage number in rat thy-1 nephritis. J Am Soc Nephrol. 2003;14:848-54 pubmed
    ..This article reports the effects of Ras antagonist farnesylthiosalicylic acid (FTS) in rat thy-1 nephritis, a model in which cytokine-driven glomerular cell proliferation and invasion is likely to involve Ras signaling ..
  51. Akagami M, Shibahara T, Yoshiga T, Tanaka N, Yaguchi Y, Onuki T, et al. Granulomatous nephritis and meningoencephalomyelitis caused by Halicephalobus gingivalis in a pony gelding. J Vet Med Sci. 2007;69:1187-90 pubmed
    ..gingivalis. The present results indicated that H. gingivalis caused granulomatous nephritis and meningoencephalomyelitis in this pony gelding.
  52. Wang Y, He Q, Qin H, Xu J, Tong J, Gao L, et al. The complement C5b-9 complexes induced injury of glomerular mesangial cells in rats with Thy-1 nephritis by increasing nitric oxide synthesis. Life Sci. 2006;79:182-92 pubmed
    Thy-1 nephritis (Thy-1 N), namely, anti-Thy-1 or anti-thymocyte serum (ATS) induced nephritis (ATSN), is a typical model of human mesangioproliferative glomerulonephritis...
  53. Togawa A, Yamamoto T, Suzuki H, Fukasawa H, Ohashi N, Fujigaki Y, et al. Ubiquitin-dependent degradation of Smad2 is increased in the glomeruli of rats with anti-thymocyte serum nephritis. Am J Pathol. 2003;163:1645-52 pubmed
    ..this study, we investigated the regulation of Smad proteins in the glomeruli of rats with anti-thymocyte serum nephritis. We found that Smad2 protein decreased markedly in nephritic glomeruli, whereas no significant changes were ..