pruritus vulvae

Summary

Summary: Intense itching of the external female genitals.

Top Publications

  1. Boardman L, Botte J, Kennedy C. Recurrent vulvar itching. Obstet Gynecol. 2005;105:1451-5 pubmed
  2. Dahiya P, Agarwal U, Sangwan K, Chauhan M. Long retained intravaginal foreign body: a case report. Arch Gynecol Obstet. 2003;268:323-4 pubmed
    ..Recurrent, unremitting, foul-smelling, bloody vaginal discharge in a child should alert the clinician to the possibility of a retained vaginal foreign body...
  3. Welsh B, Howard A, Cook K. Vulval itch. Aust Fam Physician. 2004;33:505-10 pubmed
    ..Excoriation, rubbing, maceration, secondary infection and the effects of topical applications frequently complicate matters...
  4. Bachmann G, Arnold L. Recurrent vulvar itching. Obstet Gynecol. 2005;106:639; author reply 639 pubmed
  5. Farage M, Miller K, Ledger W. Determining the cause of vulvovaginal symptoms. Obstet Gynecol Surv. 2008;63:445-64 pubmed publisher
    ..Additionally, this review describes how such features of the clinical presentation can help identify various causes of vulvovaginitis...
  6. Lewis F, Shah M, Gawkrodger D. Contact sensitivity in pruritus vulvae: patch test results and clinical outcome. Am J Contact Dermat. 1997;8:137-40 pubmed
    ..Patients with established vulval disease may develop contact sensitivity as a secondary problem after the application of topical therapy...
  7. Muppala H, Meskhi A. Voiding dysfunction due to long-standing labial fusion in an elderly woman: a case report. Int Urogynecol J Pelvic Floor Dysfunct. 2009;20:251-2 pubmed publisher
    ..We describe a case of near-complete labial fusion in an elderly woman presenting with voiding difficulty, its management and literature review. ..
  8. Bell H, Farrar C, Curley R. Papular acantholytic dyskeratosis of the vulva. Clin Exp Dermatol. 2001;26:386-8 pubmed
    ..We feel that the findings in our patients are consistent with a diagnosis of papular acantholytic dyskeratosis of the vulva, a rare condition, which was first described in 1984. ..
  9. Nowakowska D, Kurnatowska A, Wilczynski J. [Relationship between activity of hydrolases in fungi isolated from vagina of pregnant women and selected symptoms]. Wiad Parazytol. 2002;48:263-9 pubmed
    ..Out of the 19 examined hydrolazes, 13 active enzymes were detected in fungal strains. We found for the first time the relationship between activity of fungal esterase lipase and the presence of vaginal discharge in pregnant women. ..

More Information

Publications70

  1. Bohl T. Overview of vulvar pruritus through the life cycle. Clin Obstet Gynecol. 2005;48:786-807 pubmed
  2. Klufio C, Amoa A, Delamare O, Hombhanje M, Kariwiga G, Igo J. Prevalence of vaginal infections with bacterial vaginosis, Trichomonas vaginalis and Candida albicans among pregnant women at the Port Moresby General Hospital Antenatal Clinic. P N G Med J. 1995;38:163-71 pubmed
    ..A randomized, controlled prospective study is needed to assess the extent to which, if any, these infections are related to the high perinatal morbidity and mortality from low birth weight at Port Moresby General Hospital. ..
  3. Virgili A, Levratti A, Zampino M, Corazza M. Are patch tests useful in plasma cell vulvitis?. J Reprod Med. 2004;49:105-7 pubmed
    ..Patch testing is not normally necessary in the management of PCV. However, when a patient with PCV complains of burning or pruritus after application of topical products, patch tests could prove useful. ..
  4. Welsh B. Patient education. Good vulval care. Aust Fam Physician. 2004;33:517 pubmed
  5. Al Zanbagi N, Al Jehani E. Recent diagnostic study for the flagellate protozoan Trichomonas vaginalis. J Egypt Soc Parasitol. 2007;37:361-70 pubmed
    ..4% positive predictive value and 95% negative predictive value. InPouch TV culture showed 86.7% sensitivity, 100% specificity, 100% positive predictive value and 98.7% negative predictive value. The results were discussed...
  6. Herod J, Shafi M, Rollason T, Jordan J, Luesley D. Vulvar intraepithelial neoplasia with superficially invasive carcinoma of the vulva. Br J Obstet Gynaecol. 1996;103:453-6 pubmed
    ..To investigate the long-term outcome of patients presenting with vulvar intraepithelial neoplasia (VIN) with superficially invasive carcinoma of the vulva (SICa)...
  7. Foster D. Vulvar disease. Obstet Gynecol. 2002;100:145-63 pubmed
    ..This review of vulvar disease highlights a number of common and problematic vulvar conditions. Treatment options for vulvar conditions are covered with an expanded discussion of newer immune response modifiers...
  8. Weichert G. An approach to the treatment of anogenital pruritus. Dermatol Ther. 2004;17:129-33 pubmed
    ..Specific terms for chronic itch in this location have included pruritus vulvae, pruritus ani, lichen simplex chronicus, and neurodermatitis...
  9. Weisshaar E. Successful treatment of genital pruritus using topical immunomodulators as a single therapy in multi-morbid patients. Acta Derm Venereol. 2008;88:195-6 pubmed publisher
  10. DeAmbrosis K, Nicklin J, Yong Gee S. Basal cell carcinoma of the vulva: a report of four cases. Australas J Dermatol. 2008;49:213-5 pubmed publisher
    ..Subsequent treatment in all cases involved wide local excision following incisional biopsy. No recurrence has been documented after a minimum follow-up period of 12 months...
  11. Corazza M, Virgili A, Toni G, Minghetti S, Tiengo S, Borghi A. Level of use and safety of botanical products for itching vulvar dermatoses. Are patch tests useful?. Contact Dermatitis. 2016;74:289-94 pubmed publisher
    ..Topical remedies based on botanical ingredients are popular...
  12. Haverhoek E, Reid C, Gordon L, Marshman G, Wood J, Selva Nayagam P. Prospective study of patch testing in patients with vulval pruritus. Australas J Dermatol. 2008;49:80-5 pubmed publisher
    ..Most importantly, many clinically relevant allergens these patients reacted to were outside the European standard series. This highlights the need for an extended series in this patient population...
  13. Kavala M, Can B, Zindanci I, Kocaturk E, Turkoglu Z, Buyukbabani N, et al. Vulvar pruritus caused by syringoma of the vulva. Int J Dermatol. 2008;47:831-2 pubmed publisher
  14. Edwards L. New concepts in vulvodynia. Am J Obstet Gynecol. 2003;189:S24-30 pubmed
    ..Importantly, any therapy should be accompanied by patient education and psychological support. Because definitive data on effective therapies are lacking, further clinical investigations of treatment options are warranted...
  15. Hoffstetter S, Barr S, LeFevre C, Gavard J. Telephone triage: diagnosis of candidiasis based upon self-reported vulvovaginal symptoms. J Low Genit Tract Dis. 2012;16:251-5 pubmed publisher
  16. Pincus S. Vulvar dermatoses and pruritus vulvae. Dermatol Clin. 1992;10:297-308 pubmed
    ..There is no easy answer, yet the recognition that the process is treatable, if not curable, should provide encouragement for both patients and their physicians...
  17. Jang N, Fischer G. Treatment of erosive vulvovaginal lichen planus with methotrexate. Australas J Dermatol. 2008;49:216-9 pubmed publisher
    ..03-0.10% ointment. All cases experienced improvement in symptoms and healing of lesions within 4-8 weeks. Methotrexate was well tolerated and no adverse events have been observed in any of the patients at follow up 4-6 months later...
  18. Madnani N, Bhalerao Gandhi A, Khan K. Vulvar puritus for one year. Dermatol Online J. 2010;16:10 pubmed
    ..A swab from the plaque did not grow any organism. Routine blood chemistry including a VDRL and HIV ELIZA were within normal limits. A punch biopsy from the lesion was taken and histopathology findings were as seen in (Figures 2 and 3)...
  19. Yin Y, Zhou X, Wang Y, Song L, Duan Y. [Observation of therapeutic effect on perineal, crissal and progenital pruritus treated with acupuncture according to differentiation]. Zhongguo Zhen Jiu. 2011;31:409-12 pubmed
    ..To observe the therapeutic effect and safety of perineal, crissal and progenital pruritus treated with acupuncture according to differentiation...
  20. McKay M. Vulvitis and vulvovaginitis: cutaneous considerations. Am J Obstet Gynecol. 1991;165:1176-82 pubmed
    ..Few skin diseases are curable but all are treatable; effective management is defined by whether a medication reliably controls outbreaks or symptoms when it is used. Patience is recommended, because treatment may take weeks or months...
  21. Bornstein J, Pascal B, Sova Y, Rosenfeld Y, Abramovici H. [The vulvar clinic]. Harefuah. 1990;119:413-6 pubmed
    ..The vulvar clinic contributes to the ambulatory gynecological service by concentrating diagnosis and treatment in a single specialized unit and increases understanding of, and interest in vulvar disease...
  22. Parks G, Growdon W, Mason G, Goldman L, Lebherz T. Childhood anogenital lichen sclerosus. A case report. J Reprod Med. 1990;35:191-3 pubmed
    ..The child was treated with 2% progesterone cream, with complete resolution of her pruritic symptoms and signs of traumatic injury to the vulvar skin. The basic condition, lichen sclerosus, has persisted...
  23. Fischer G. The commonest causes of symptomatic vulvar disease: a dermatologist's perspective. Australas J Dermatol. 1996;37:12-8 pubmed
    ..A review of the commonest vulvar conditions seen by the author is presented...
  24. Kuczkowski K. Perineal pruritus and dexamethasone. Anaesthesia. 2004;59:308 pubmed
  25. Lagro Janssen A, Sluis S. Effectiveness of treating non-specific pruritus vulvae with topical steroids: a randomized controlled trial. Eur J Gen Pract. 2009;15:29-33 pubmed publisher
    To determine the effectiveness of triamcinolone cream in the treatment of non-specific pruritus vulvae.
  26. Currie J, Mott L, Pennisi S, Smith B, Smith R. Potential for an external vaginal antiitch cream containing benzocaine to cause methemoglobinemia in healthy women. Am J Obstet Gynecol. 1997;176:1006-8 pubmed
    ..Our purpose was to assess the potential for an external vaginal antiitch cream (20% benzocaine, 3% resorcinol) to significantly increase levels of methemoglobin above normal in healthy women...
  27. Kelekci H, Uncu H, Yilmaz B, Ozdemir O, Sut N, Kelekci S. Pimecrolimus 1% cream for pruritus in postmenopausal diabetic women with vulvar lichen simplex chronicus: a prospective non-controlled case series. J Dermatolog Treat. 2008;19:274-8 pubmed publisher
    b>Pruritus vulvae may have a variety of causes, such as infections, dermatologic disorders or non-neoplastic/neoplastic vulvar diseases.
  28. Urman B, Yuce K, Ayhan A, Gokoz A. Topical testosterone for lichen sclerosus. Int J Gynaecol Obstet. 1989;30:253-5 pubmed
    ..7%; 8.7% of the patients experienced undesirable androgenic side effects. Of the three patients who did not respond satisfactorily to testosterone treatment, two had alcohol injection to the vulva and one had vulvar denervation...
  29. Margesson L. Vulvovaginal dryness and itching. Skin Therapy Lett. 2001;6:3-4 pubmed
    ..Dermatologists should be able to sort out the causes of the itching and irritation, and understand the approaches to therapy...
  30. Stanosz S, Sycz G, Borowiak M. [Effect of immunotherapy on the level of immunoglobulin in serum of women with pruritus of the vulva]. Ginekol Pol. 1992;63:348-51 pubmed
    ..The auto-vaccine caused a significant (p < 0.05) increase of IgG and IgM and significant (p < 0.05) decrease of IgA and IgE, as compared with initial values...
  31. LeFevre C, Hoffstetter S, Meyer S, Gavard J. Management of lichen sclerosus with triamcinolone ointment: effectiveness in reduction of patient symptom scores. J Low Genit Tract Dis. 2011;15:205-9 pubmed publisher
    ..To determine whether topical triamcinolone ointment effectively reduces patient's symptoms for the management of lichen sclerosus (LS)...
  32. Kelekci K, Adamhasan F, Gencdal S, Sayar H, Kelekci S. The impact of the latest classification system of benign vulvar diseases on the management of women with chronic vulvar pruritus. Indian J Dermatol Venereol Leprol. 2011;77:294-9 pubmed publisher
    ..The management of women with chronic benign vulvar dermatoses has been one of the most difficult and challenging aspects of women's healthcare for a long time...
  33. Carter J, Elliott P. Syringoma--an unusual cause of pruritus vulvae. Aust N Z J Obstet Gynaecol. 1990;30:382-3 pubmed
    ..Unexpectantly the diagnosis of syringoma was made on pathological examination of biopsy specimens. This unusual case is presented as the presenting symptoms and macroscopic appearance was atypical for syringoma...
  34. Gerdsen R, Wenzel J, Uerlich M, Bieber T, Petrow W. Periodic genital pruritus caused by syringoma of the vulva. Acta Obstet Gynecol Scand. 2002;81:369-70 pubmed
  35. Tay S. Efficacy of inosine pranobex oral therapy in subclinical human papillomavirus infection of the vulva: a randomized double-blinded placebo controlled study. Int J STD AIDS. 1996;7:276-80 pubmed
    ..1%) and 9 (37.5%) patients in the respective groups showed significant improvement in the severity of pruritus vulvae (P = 0.435). Twelve (66.7%) of 18 patients with morphological improvement compared to 10 (35...
  36. Pucheu S. Joan: 'it itches, it burns': psychoanalytic approach to a case of vulvar burning syndrome. J Psychosom Obstet Gynaecol. 1998;19:175-81 pubmed
    ..A close collaboration between the physician and the psychotherapist is needed to improve the treatment of pathologies involved in a chronic pain syndrome, where psychological factors may play an important part...
  37. Rucklidge J, Saunders D. Hypnosis in a case of long-standing idiopathic itch. Psychosom Med. 1999;61:355-8 pubmed
    ..This article presents the results of a brief hypnosis treatment of a woman with chronic, idiopathic vaginal and anal itch...
  38. Utas S, Ferahbas A, Yildiz S. Patients with vulval pruritus: patch test results. Contact Dermatitis. 2008;58:296-8 pubmed publisher
    ..Allergic contact sensitivity is an important factor in such patients but may also occur as a secondary event in women with vulval dermatoses...
  39. Acosta M, Cazorla D, Garvett M. [Enterobiasis among schoolchildren in a rural population from Estado Falcón, Venezuela, and its relation with socioeconomic level]. Invest Clin. 2002;43:173-81 pubmed
  40. Engman M, Wijma K, Wijma B. Itch and burning pain in women with partial vaginismus with or without vulvar vestibulitis. J Sex Marital Ther. 2007;33:171-86 pubmed
    ..In 17 of 22 cases, burning pain preceded the appearance of itch and in four cases the two complaints coincided. The median time from the moment when burning pain started until itch appeared was 150 seconds...
  41. Bates S, Dilke Wing G. Determination of iron status in women attending genitourinary clinics with pruritus vulvae. Sex Transm Infect. 2006;82:489-90 pubmed
    To compare iron status in women with pruritus vulvae and in asymptomatic controls.
  42. Haustein U. [Pruritus of the artificial vagina of a transsexual patient caused by gonococcal infection]. Hautarzt. 1995;46:858-9 pubmed
    ..Despite the regularly stratified epithelium of the neovagina, which is physiologically resistant to gonococcal infection, this possibility must be considered in transsexual prostitutes...
  43. Kopera D, Soyer H, Cerroni L. Vulvar syringoma causing pruritus and carcinophobia: treatment by argon laser. J Cutan Laser Ther. 1999;1:181-3 pubmed
    ..g. face, neck, arms) or pruritus (e.g. vulva). This is the first report of argon laser treatment of syringoma in a patient with multiple vulvar syringomas in association with pruritus vulvae and carcinophobia.
  44. Sarifakioglu E, Gumus I. Efficacy of topical pimecrolimus in the treatment of chronic vulvar pruritus: a prospective case series--a non-controlled, open-label study. J Dermatolog Treat. 2006;17:276-8 pubmed
    ..Potent topical steroids are the conventional therapy for this distressing condition. Side effects or steroid resistance can be encountered. A second-line therapy is required...
  45. da Silva B, Borges U, Pimentel I. Human vaginal myiasis caused by Cochliomyia hominivorax. Int J Gynaecol Obstet. 2005;89:152-3 pubmed
  46. Banerjee A, de Chazal R. Chronic vulvovaginal pruritus treated successfully with GnRH analogue. Postgrad Med J. 2006;82:e22 pubmed
    ..The report describes a patient with chronic premenstrual vulvovaginal pruritus thought to be attributable to autoimmune progesterone dermatitis...
  47. Origoni M, Garsia S, Sideri M, Pifarotti G, Nicora M. Efficacy of topical oxatomide in women with pruritus vulvae. Drugs Exp Clin Res. 1990;16:591-6 pubmed
    b>Pruritus vulvae is a very common condition. The patient's scratching often worsens the situation and makes diagnosis by the clinician difficult...
  48. Day S. Threadworm: an infrequent clinical finding in a genitourinary medicine clinic attendee presenting with ano-genital irritation. Int J STD AIDS. 2009;20:362-3 pubmed publisher
    ..Threadworm is a common and easily treatable cause of pruritus ani, yet is underreported in GU literature. If the history is suggestive, consider performing the diagnostic cellophane test and/or prescribing empirical treatment...
  49. Edwards Q, Saunders Goldson S, Morgan P, Maradiegue A, Macri C. Vulvar intraepithelial neoplasia: varied signs, varied symptoms: what you need to know. Adv Nurse Pract. 2005;13:49-52 pubmed
  50. Sener A, Kuscu E, Seckin N, Gokmen O, Taner D, Cobanoglu O, et al. Postmenopausal vulvar pruritus--colposcopic diagnosis and treatment. J Pak Med Assoc. 1995;45:315-7 pubmed
    ..94% and 0.07% respectively. Vulvar dystrophies were treated by topical steroids and success rate was 100%. All patients with vulvar pruritus need examination under colposcopy to define optimal therapy and to exclude atypia or malignancy...
  51. Kehoe S, Luesley D. Pathology and management of vulval pain and pruritus. Curr Opin Obstet Gynecol. 1995;7:16-9 pubmed
    ..The natural history and management of these and benign disorders have been reported during the period of review. Some of the new findings may alter present concepts and practices...
  52. Zamirska A, Reich A, Berny Moreno J, Salomon J, Szepietowski J. Vulvar pruritus and burning sensation in women with psoriasis. Acta Derm Venereol. 2008;88:132-5 pubmed publisher
    ..05). We conclude that vulvar discomfort is an important clinical problem in women with psoriasis and should be taken into consideration during treatment...
  53. Villarreal L, de Frutos F, del Prado Sánchez Caminero M, Sebastián F. Perineal allergic contact dermatitis due to tetracaine in a urological lubricant. Contact Dermatitis. 2004;51:321-2 pubmed
  54. Petersen C, Kristensen E, Lundvall L, Giraldi A. A retrospective study of relevant diagnostic procedures in vulvodynia. J Reprod Med. 2009;54:281-7 pubmed
    ..To identify objective clinical signs of vulvodynia and determine specific diagnostic tests for vulvodynia in women referred to a vulvar outpatient clinic for vulval complaints...
  55. Stewart K. Clinical care of vulvar pruritus, with emphasis on one common cause, lichen simplex chronicus. Dermatol Clin. 2010;28:669-80 pubmed publisher
    ..This article provides a practical and clinical approach to the evaluation of vulvar pruritus and then focuses specifically on one common cause, lichen simplex chronicus...
  56. Soper D, Patterson J, Hurt W, Fantl J, Blaylock W. Lichen planus of the vulva. Obstet Gynecol. 1988;72:74-6 pubmed
    ..Marked resorption of the labia minor and atrophy may occur in time. Diagnosis is based on associated clinical findings involving the oral mucosa and/or the skin and on vulvar biopsy...
  57. Guzel A, Kuyumcuoglu U, Celik Y. Vaginal douching practice and related symptoms in a rural area of Turkey. Arch Gynecol Obstet. 2011;284:1153-6 pubmed publisher
    ..To investigate vaginal douching habits and associated factors among women living in rural Turkey...
  58. Margesson L. Overview of treatment of vulvovaginal disease. Skin Therapy Lett. 2011;16:5-7 pubmed
    ..Dermatologists are invaluable for management as they recognize skin problems and can correct barrier function, control inflammation, and address itching and pain...
  59. Kelly R, Foster D, Woodruff J. Subcutaneous injection of triamcinolone acetonide in the treatment of chronic vulvar pruritus. Am J Obstet Gynecol. 1993;169:568-70 pubmed
    ..We studied the efficacy of subcutaneous corticosteroid injection as therapy for chronic vulvar pruritus...
  60. Ozalp S, Telli E, Yalcin O, Oge T, Karakas N. Vulval pruritus: the experience of gynaecologists revealed by biopsy. J Obstet Gynaecol. 2015;35:53-6 pubmed publisher
    ..5%, n = 35; 20.4%, n = 28; 14.6%, n = 20). In conclusion, several pathologies out of vulvovaginal candidiasis may lead to vulval pruritus and clinicians should be aware of the importance of biopsy in determining the underlying pathology...
  61. Tay Y, Tham S, Teo R. Localized vulvar syringomas--an unusual cause of pruritus vulvae. Dermatology. 1996;192:62-3 pubmed
    Genital syringomas are rare and usually asymptomatic. We report 2 young women who presented with pruritus vulvae. Examination revealed multiple bilateral skin-coloured papules over the labia majora. Histology showed syringoma...