retinopathy of prematurity

Summary

Summary: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Top Publications

  1. Moral Pumarega M, Caserío Carbonero S, de la Cruz Bértolo J, Tejada Palacios P, Lora Pablos D, Pallás Alonso C. Pain and stress assessment after retinopathy of prematurity screening examination: indirect ophthalmoscopy versus digital retinal imaging. BMC Pediatr. 2012;12:132 pubmed publisher
    ..with a binocular indirect ophthalmoscope is the reference examination technique for screening of retinopathy of prematurity (ROP), and it is associated with pain and stress...
  2. Darlow B, Ells A, Gilbert C, Gole G, Quinn G. Are we there yet? Bevacizumab therapy for retinopathy of prematurity. Arch Dis Child Fetal Neonatal Ed. 2013;98:F170-4 pubmed publisher
    The publication of the BEAT-ROP study of bevacizumab (Avastin) treatment for Zone I and II retinopathy of prematurity (ROP) has raised hopes that there might now be a simpler, cheaper and more effective treatment than laser therapy, the ..
  3. Bremer D, Rogers D, Good W, Tung B, Hardy R, Fellows R. Glaucoma in the Early Treatment for Retinopathy of Prematurity (ETROP) study. J AAPOS. 2012;16:449-52 pubmed publisher
    To report the clinical characteristics of infants with severe retinopathy of prematurity (ROP) and glaucoma-based on review of the Early Treatment for Retinopathy of Prematurity (ETROP) study...
  4. Askie L, Brocklehurst P, Darlow B, Finer N, Schmidt B, Tarnow Mordi W. NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol. BMC Pediatr. 2011;11:6 pubmed publisher
    ..oxygen saturations of >90%) have been reported to have greater rates of morbidity including retinopathy of prematurity and chronic lung disease...
  5. Lofqvist C, Hansen Pupp I, Andersson E, Holm K, Smith L, Ley D, et al. Validation of a new retinopathy of prematurity screening method monitoring longitudinal postnatal weight and insulinlike growth factor I. Arch Ophthalmol. 2009;127:622-7 pubmed publisher
    To validate in a prospective study the surveillance algorithm WINROP for detecting infants at risk for proliferative retinopathy of prematurity (ROP).
  6. Hu J, Blair M, Shapiro M, Lichtenstein S, Galasso J, Kapur R. Reactivation of retinopathy of prematurity after bevacizumab injection. Arch Ophthalmol. 2012;130:1000-6 pubmed
    To report late reactivation and progression of retinopathy of prematurity (ROP) after intravitreal bevacizumab monotherapy...
  7. Shastry B. Assessment of the contribution of insulin-like growth factor I receptor 3174 G-->A polymorphism to the progression of advanced retinopathy of prematurity. Eur J Ophthalmol. 2007;17:950-3 pubmed
    b>Retinopathy of prematurity (ROP) is a leading cause of blindness in children with short gestational age and low birthweight. The condition can cause abnormal vessel development that can lead to retinal detachment and blindness...
  8. Gunn D, Cartwright D, Gole G. Incidence of retinopathy of prematurity in extremely premature infants over an 18-year period. Clin Exp Ophthalmol. 2012;40:93-9 pubmed publisher
    To report the incidence of retinopathy of prematurity (ROP) in a subgroup of extremely premature infants admitted to an Australian tertiary centre over an 18-year period. Retrospective study...
  9. Micelli Ferrari T, Furino C, Lorusso V, Dammacco R, Sborgia G, Sborgia L, et al. Three-port lens-sparing vitrectomy for aggressive posterior retinopathy of prematurity: early surgery before tractional retinal detachment appearance. Eur J Ophthalmol. 2007;17:785-9 pubmed
    Aggressive posterior retinopathy of prematurity (APROP) may suddenly develop into tractional retinal detachment (TRD), often resulting in poor vision if untreated...

More Information

Publications72

  1. Zin A, Gole G. Retinopathy of prematurity-incidence today. Clin Perinatol. 2013;40:185-200 pubmed publisher
    b>Retinopathy of prematurity (ROP) in high-income countries now occurs, mostly in extreme low birth weight infants. In those countries, the incidence of ROP seems to have declined incrementally over the last few decades...
  2. Husain S, Sinha A, Bunce C, Arora P, López W, Mun K, et al. Relationships between maternal ethnicity, gestational age, birth weight, weight gain, and severe retinopathy of prematurity. J Pediatr. 2013;163:67-72 pubmed publisher
    To develop an algorithm that allows advanced identification of infants requiring treatment for retinopathy of prematurity (ROP).
  3. Sanghi G, Dogra M, Dutta S, Katoch D, Gupta A. Intersibling variability of retinopathy of prematurity in twins and its risk factors. Int Ophthalmol. 2012;32:113-7 pubmed publisher
    To study intersibling variability of retinopathy of prematurity (ROP) in twins and determine its risk factors...
  4. Gupta V, Whelan K, Schneider L, Farrokhyar F, Shivananda S, Lee S, et al. National variations in retinopathy of prematurity screening criteria in Canada: existent guidelines and actual practice patterns. Can J Ophthalmol. 2012;47:473-8 pubmed publisher
    To survey the current inclusion criteria used for retinopathy of prematurity (ROP) screening across tertiary level 3 neonatal intensive care units (NICUs) in Canada.
  5. Fortes Filho J, Borges Fortes B, Tartarella M, Procianoy R. Incidence and main risk factors for severe retinopathy of prematurity in infants weighing less than 1000 grams in Brazil. J Trop Pediatr. 2013;59:502-6 pubmed publisher
    This study evaluated the incidence and risk factors for severe retinopathy of prematurity (ROP) in babies <1000 g at Porto Alegre, Brazil.
  6. Shah P, Narendran V, Kalpana N. Aggressive posterior retinopathy of prematurity in large preterm babies in South India. Arch Dis Child Fetal Neonatal Ed. 2012;97:F371-5 pubmed publisher
    To describe aggressive posterior retinopathy of prematurity (APROP) in a subset of premature babies, having gestational age (GA) of ?28 weeks and birth weight (BW) of ?1000 g.
  7. Parad R, Allred E, Rosenfeld W, Davis J. Reduction of retinopathy of prematurity in extremely low gestational age newborns treated with recombinant human Cu/Zn superoxide dismutase. Neonatology. 2012;102:139-44 pubmed publisher
    Reactive oxygen species have been implicated in the pathogenesis of retinopathy of prematurity (ROP). Extremely low gestational age (GA) newborns (ELGANs) have the highest risk of ROP and might benefit most from treatment with antioxidants...
  8. Chu Z, Wang Y. [Incidence of retinopathy of prematurity in mainland of China over the last 20 years]. Zhonghua Yan Ke Za Zhi. 2012;48:179-83 pubmed
    b>Retinopathy of prematurity (ROP) is one of the important causes of childhood blindness in China with an increasing trend of affected infants. It gives great burden on both the individuals and the society...
  9. Lundgren P, Stoltz Sjöström E, Domellöf M, Kallen K, Holmstrom G, Hard A, et al. WINROP identifies severe retinopathy of prematurity at an early stage in a nation-based cohort of extremely preterm infants. PLoS ONE. 2013;8:e73256 pubmed publisher
    To evaluate the ability of a postnatal weight-gain algorithm (WINROP) to identify sight-threatening retinopathy of prematurity (ROP type 1) in a nation-based extremely preterm infant cohort.
  10. Wu C, Lofqvist C, Smith L, Vanderveen D, Hellstrom A. Importance of early postnatal weight gain for normal retinal angiogenesis in very preterm infants: a multicenter study analyzing weight velocity deviations for the prediction of retinopathy of prematurity. Arch Ophthalmol. 2012;130:992-9 pubmed
    To assess WINROP (https://winrop.com), an algorithm using postnatal weight measurements, as a tool for the prediction of retinopathy of prematurity (ROP) in a large geographically and racially diverse study population.
  11. Hellstrom A, Smith L, Dammann O. Retinopathy of prematurity. Lancet. 2013;382:1445-57 pubmed publisher
    ..retinas of preterm neonates are susceptible to insults that disrupt neurovascular growth, leading to retinopathy of prematurity. Suppression of growth factors due to hyperoxia and loss of the maternal-fetal interaction result in an ..
  12. Levesque B, Kalish L, Winston A, Parad R, Hernandez diaz S, Phillips M, et al. Low urine vascular endothelial growth factor levels are associated with mechanical ventilation, bronchopulmonary dysplasia and retinopathy of prematurity. Neonatology. 2013;104:56-64 pubmed publisher
    ..factor (VEGF) expression is decreased during the pathogenesis of bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) several weeks before either disease can be diagnosed...
  13. Lee J, Dammann O. Perinatal infection, inflammation, and retinopathy of prematurity. Semin Fetal Neonatal Med. 2012;17:26-9 pubmed publisher
    The major known risk factors for retinopathy of prematurity (ROP) are extremely low gestational age, exposure to high levels of oxygen early after birth (phase I) and relatively lower oxygen levels later (phase II)...
  14. Sato T, Wada K, Arahori H, Kuno N, Imoto K, Iwahashi Shima C, et al. Serum concentrations of bevacizumab (avastin) and vascular endothelial growth factor in infants with retinopathy of prematurity. Am J Ophthalmol. 2012;153:327-333.e1 pubmed publisher
    ..the serum concentrations of bevacizumab and vascular endothelial growth factor (VEGF) in infants with retinopathy of prematurity (ROP) who received intravitreal bevacizumab; and to determine whether the changes in the serum ..
  15. Cavallaro G, Filippi L, Bagnoli P, la Marca G, Cristofori G, Raffaeli G, et al. The pathophysiology of retinopathy of prematurity: an update of previous and recent knowledge. Acta Ophthalmol. 2014;92:2-20 pubmed publisher
    b>Retinopathy of prematurity (ROP) is a disease that can cause blindness in very low birthweight infants. The incidence of ROP is closely correlated with the weight and the gestational age at birth...
  16. Gammons M, Dick A, Harper S, Bates D. SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2013;54:5797-806 pubmed publisher
    ..that recombinant human VEGF-A165b and the serine arginine protein kinase (SRPK) inhibitor, SRPIN340, which controls splicing of the VEGF-A pre-mRNA, prevent neovascularization in a rodent model of retinopathy of prematurity (ROP).
  17. Doyle K, Bradshaw W. Sixty golden minutes. Neonatal Netw. 2012;31:289-94 pubmed publisher
    ..To a premature baby, the first 60 minutes of life are golden and can last a lifetime...
  18. Hakeem A, Mohamed G, Othman M. Retinopathy of prematurity: a study of prevalence and risk factors. Middle East Afr J Ophthalmol. 2012;19:289-94 pubmed publisher
    b>Retinopathy of prematurity (ROP) is a serious complication of prematurity treatment and can lead to blindness unless recognized and treated early.
  19. Araz Ersan B, Kir N, Akarcay K, Aydinoglu Candan O, Sahinoglu Keskek N, Demirel A, et al. Epidemiological analysis of retinopathy of prematurity in a referral centre in Turkey. Br J Ophthalmol. 2013;97:15-7 pubmed publisher
    To collect data towards the establishment of a guideline to predict the population under risk for the development of retinopathy of prematurity (ROP) in Turkey.
  20. Dave H, Gordillo L, Yang Z, Zhang M, Hubbard G, Olsen T. The societal burden of blindness secondary to retinopathy of prematurity in Lima, Peru. Am J Ophthalmol. 2012;154:750-5 pubmed publisher
    To determine the cost-effectiveness of laser treatment for retinopathy of prematurity (ROP) in Lima, Peru.
  21. Wilson C, Ells A, Fielder A. The challenge of screening for retinopathy of prematurity. Clin Perinatol. 2013;40:241-59 pubmed publisher
    Screening for retinopathy of prematurity (ROP) and the optimum treatment of sight-threatening disease requires detailed understanding of the infants at risk and timely identification...
  22. Blencowe H, Lawn J, Vazquez T, Fielder A, Gilbert C. Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010. Pediatr Res. 2013;74 Suppl 1:35-49 pubmed publisher
    b>Retinopathy of prematurity (ROP) is a leading cause of potentially avoidable childhood blindness worldwide. We estimated ROP burden at the global and regional levels to inform screening and treatment programs, research, and data priorities...
  23. Van der Merwe S, Freeman N, Bekker A, Harvey J, Smith J. Prevalence of and risk factors for retinopathy of prematurity in a cohort of preterm infants treated exclusively with non-invasive ventilation in the first week after birth. S Afr Med J. 2013;103:96-100 pubmed publisher
    To determine the current prevalence of retinopathy of prematurity (ROP) in premature babies treated with non-invasive ventilation at Tygerberg Children's Hospital, Parow, Cape Town, South Africa, and to identify risk factors associated ..
  24. Dani C, Lori I, Favelli F, Frosini S, Messner H, Wanker P, et al. Lutein and zeaxanthin supplementation in preterm infants to prevent retinopathy of prematurity: a randomized controlled study. J Matern Fetal Neonatal Med. 2012;25:523-7 pubmed publisher
    ..Our aim was to evaluate whether their administration could help decrease the occurrence of retinopathy of prematurity (ROP) in preterm infants...
  25. Romagnoli C, Giannantonio C, Cota F, Papacci P, Vento G, Valente E, et al. A prospective, randomized, double blind study comparing lutein to placebo for reducing occurrence and severity of retinopathy of prematurity. J Matern Fetal Neonatal Med. 2011;24 Suppl 1:147-50 pubmed publisher
    ..We hypothesize that lutein administration may contribute to reducing the incidence of Retinopathy of Prematurity (ROP). This was a single center, double-blind randomized controlled study...
  26. Simpson J, Melia M, Yang M, Buffenn A, Chiang M, Lambert S. Current role of cryotherapy in retinopathy of prematurity: a report by the American Academy of Ophthalmology. Ophthalmology. 2012;119:873-7 pubmed publisher
    To evaluate the role of cryotherapy in the current treatment of retinopathy of prematurity (ROP).
  27. Dempsey E, McCreery K. Local anaesthetic eye drops for prevention of pain in preterm infants undergoing screening for retinopathy of prematurity. Cochrane Database Syst Rev. 2011;:CD007645 pubmed publisher
    Screening examinations for retinopathy of prematurity (ROP) are performed routinely in the neonatal intensive care unit and are a recognised cause of pain in the newborn.
  28. McCloskey M, Wang H, Jiang Y, Smith G, Strange J, Hartnett M. Anti-VEGF antibody leads to later atypical intravitreous neovascularization and activation of angiogenic pathways in a rat model of retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2013;54:2020-6 pubmed publisher
    ..neovascularization (IVNV), avascular retina (AVA), and retinal detachment in preterm infants with retinopathy of prematurity (ROP). We sought to understand causes of late-onset IVNV and AVA following anti-VEGF using an ROP model.
  29. Schmidt B, Whyte R, Asztalos E, Moddemann D, Poets C, Rabi Y, et al. Effects of targeting higher vs lower arterial oxygen saturations on death or disability in extremely preterm infants: a randomized clinical trial. JAMA. 2013;309:2111-20 pubmed publisher
    ..The goal of oxygen therapy is to deliver sufficient oxygen to the tissues while minimizing oxygen toxicity and oxidative stress. It remains uncertain what values of arterial oxygen saturations achieve this balance in preterm infants...
  30. Repka M, Tung B, Good W, Capone A, Shapiro M. Outcome of eyes developing retinal detachment during the Early Treatment for Retinopathy of Prematurity study. Arch Ophthalmol. 2011;129:1175-9 pubmed publisher
    To describe the structural and visual outcomes at age 6 years of retinal detachment (RD) from retinopathy of prematurity (ROP) in the Early Treatment for Retinopathy of Prematurity (ETROP) study.
  31. Holmstrom G, Larsson E. Outcome of retinopathy of prematurity. Clin Perinatol. 2013;40:311-21 pubmed publisher
    In prematurely born children, various visual and ophthalmologic sequelae occur because of both retinopathy of prematurity (ROP) and preterm birth per se. Several long-term follow-up studies have described the outcome of ROP...
  32. Di Fiore J, Kaffashi F, Loparo K, Sattar A, Schluchter M, Foglyano R, et al. The relationship between patterns of intermittent hypoxia and retinopathy of prematurity in preterm infants. Pediatr Res. 2012;72:606-12 pubmed publisher
    ..shown an increased incidence of intermittent hypoxemia (IH) events in preterm infants with severe retinopathy of prematurity (ROP). Animal models suggest that patterns of IH events may play a role in ROP severity as well...
  33. Purcaro V, Velia P, Baldascino A, Antonio B, Papacci P, Patrizia P, et al. Fluorescein angiography and retinal vascular development in premature infants. J Matern Fetal Neonatal Med. 2012;25 Suppl 3:53-6 pubmed
    To investigate the role of fluorescein angiography (FA) in the management of retinopathy of prematurity (ROP) in preterm newborns.
  34. Vinekar A, Avadhani K, Dogra M, Sharma P, Gilbert C, Braganza S, et al. A novel, low-cost method of enrolling infants at risk for Retinopathy of Prematurity in centers with no screening program: the REDROP study. Ophthalmic Epidemiol. 2012;19:317-21 pubmed publisher
    To report the first-year results of the Red Card for Retinopathy of Prematurity (REDROP) study, a low-cost interim strategy to enroll infants into retinopathy of prematurity (ROP) screening where limited expertise exists, piloted at a ..
  35. Alpay A, Ugurbas S. Incidence and risk factors for retinopathy of prematurity in the West Black Sea region, Turkey. Turk J Pediatr. 2012;54:113-8 pubmed
    The objective of this study was to determine the incidence, risk factors and severity of retinopathy of prematurity (ROP) and to establish screening criteria for our region...
  36. Wu W, Lin R, Shih C, Wang N, Chen Y, Chao A, et al. Visual acuity, optical components, and macular abnormalities in patients with a history of retinopathy of prematurity. Ophthalmology. 2012;119:1907-16 pubmed publisher
    ..components and spectral-domain optical coherence tomography (OCT) findings in children with a history of retinopathy of prematurity (ROP) and to identify any associations between the OCT findings and the visual acuities of the patients.
  37. Narayanan S, Suwanpradid J, Saul A, Xu Z, Still A, Caldwell R, et al. Arginase 2 deletion reduces neuro-glial injury and improves retinal function in a model of retinopathy of prematurity. PLoS ONE. 2011;6:e22460 pubmed publisher
    b>Retinopathy of prematurity (ROP) is a major cause of vision impairment in low birth weight infants...
  38. Favazza T, Tanimoto N, Munro R, Beck S, Garcia Garrido M, Seide C, et al. Alterations of the tunica vasculosa lentis in the rat model of retinopathy of prematurity. Doc Ophthalmol. 2013;127:3-11 pubmed publisher
    To study the relationship between retinal and tunica vasculosa lentis (TVL) disease in retinopathy of prematurity (ROP)...
  39. Isaza G, Arora S. Incidence and severity of retinopathy of prematurity in extremely premature infants. Can J Ophthalmol. 2012;47:296-300 pubmed publisher
    To analyze incidence and severity of retinopathy of prematurity (ROP) among extremely premature infants.
  40. Woo S, Ahn J, Oh K, Lee S, Jeong E, Park K. A co-twin study of the relative effect of birth weight and gestational age on retinopathy of prematurity. Eye (Lond). 2011;25:1478-83 pubmed publisher
    To determine the relative effect of birth weight and gestational age on retinopathy of prematurity (ROP) using preterm twin pairs discordant for birth weight.
  41. Hartnett M, Lane R. Effects of oxygen on the development and severity of retinopathy of prematurity. J AAPOS. 2013;17:229-34 pubmed publisher
    In 1942, when retinopathy of prematurity (ROP) first manifested as retrolental fibroplasia, the technology to monitor or regulate oxygen did not exist, and a fundus examination of preterm infants was not routinely performed...
  42. Harder B, Von Baltz S, Jonas J, Schlichtenbrede F. Intravitreal bevacizumab for retinopathy of prematurity. J Ocul Pharmacol Ther. 2011;27:623-7 pubmed publisher
    To evaluate the therapeutic effect of a single intravitreal injection of bevacizumab for treatment of threshold retinopathy in retinopathy of prematurity (ROP).
  43. Maldonado R, O Connell R, Ascher S, Sarin N, Freedman S, Wallace D, et al. Spectral-domain optical coherence tomographic assessment of severity of cystoid macular edema in retinopathy of prematurity. Arch Ophthalmol. 2012;130:569-78 pubmed publisher
    ..edema (CME) in neonates who were 31 to 36 weeks' postmenstrual age, as viewed by spectral-domain optical coherence tomography (SD-OCT)imaging, predicts the severity of retinopathy of prematurity(ROP) or is related to systemic health.
  44. Holmström G, Hellstrom A, Jakobsson P, Lundgren P, Tornqvist K, Wallin A. Swedish national register for retinopathy of prematurity (SWEDROP) and the evaluation of screening in Sweden. Arch Ophthalmol. 2012;130:1418-24 pubmed publisher
    To evaluate screening for retinopathy of prematurity (ROP) in Sweden and to investigate possible modifications of the present screening guidelines.
  45. Slidsborg C, Forman J, Fielder A, Crafoord S, Baggesen K, Bangsgaard R, et al. Experts do not agree when to treat retinopathy of prematurity based on plus disease. Br J Ophthalmol. 2012;96:549-53 pubmed publisher
    ..levels of central vascular changes (none, mild, moderate, severe pre-plus disease, plus disease) and aggressive posterior retinopathy of prematurity (ROP), and to see whether an unintended shift in indication for treatment occurred.
  46. Tolsma K, Allred E, Chen M, Duker J, Leviton A, Dammann O. Neonatal bacteremia and retinopathy of prematurity: the ELGAN study. Arch Ophthalmol. 2011;129:1555-63 pubmed publisher
    To explore whether early or late and presumed or definite neonatal bacteremia are associated with an increased risk of severe retinopathy of prematurity (ROP).
  47. Demir S, Sayin O, Aygun C, Ortak H, Yücel O, Kucukoduk S, et al. Retinopathy of prematurity in extremely low birth weight infants in Turkey. J Pediatr Ophthalmol Strabismus. 2013;50:229-33 pubmed publisher
    This study was designed to determine the incidence rate of retinopathy of prematurity (ROP) in extremely low birth weight (ELBW) infants in the middle Black Sea region of Turkey.
  48. Kim J, Kim S, Chang Y, Park W. Combined intravitreal bevacizumab injection and zone I sparing laser photocoagulation in patients with zone I retinopathy of prematurity. Retina. 2014;34:77-82 pubmed publisher
    To investigate the anatomical outcome of combined intravitreal bevacizumab injection and Zone I sparing laser ablation in patients with Type 1 retinopathy of prematurity in Zone I.
  49. Berkowitz B, Bissig D, Bergman D, Bercea E, Kasturi V, Roberts R. Intraretinal calcium channels and retinal morbidity in experimental retinopathy of prematurity. Mol Vis. 2011;17:2516-26 pubmed
    To test the hypothesis that intraretinal calcium channels participate in retinal morbidity in a variable oxygen (VO) model of retinopathy of prematurity.
  50. Fortes Filho J, Eckert G, Tartarella M, Procianoy R. Prevention of retinopathy of prematurity. Arq Bras Oftalmol. 2011;74:217-21 pubmed
    b>Retinopathy of prematurity (ROP) is related to oxygen-regulated vascular endothelial growth factor and to insulin-like growth factor-I...
  51. Lee J, McElrath T, Chen M, Wallace D, Allred E, Leviton A, et al. Pregnancy disorders appear to modify the risk for retinopathy of prematurity associated with neonatal hyperoxemia and bacteremia. J Matern Fetal Neonatal Med. 2013;26:811-8 pubmed publisher
    ..extremely low gestational age newborns exposed to inflammation-associated pregnancy disorders differ in retinopathy of prematurity (ROP) risk from infants exposed to placenta dysfunction-associated disorders, and (2) whether ROP risk ..
  52. Gordillo L, Villanueva A, Quinn G. A practical method for reducing blindness due to retinopathy of prematurity in a developing country. J Perinat Med. 2012;40:577-82 pubmed publisher
    b>Retinopathy of prematurity (ROP) is a common cause of blindness in countries with rapidly developing systems of neonatal care...
  53. Darlow B, Gilbert C, Quiroga A. Setting up and improving retinopathy of prematurity programs: interaction of neonatology, nursing, and ophthalmology. Clin Perinatol. 2013;40:215-27 pubmed publisher
    b>Retinopathy of prematurity (ROP) programs require collaboration between neonatologists, ophthalmologists, nurses, and allied health personnel, together with parents. The concept of a ROP program will vary according to the setting...
  54. Wilson C, Wong K, Ng J, Cocker K, Ells A, Fielder A. Digital image analysis in retinopathy of prematurity: a comparison of vessel selection methods. J AAPOS. 2012;16:223-8 pubmed publisher
    To evaluate vessel selection methods to distinguish between eyes with and without retinopathy of prematurity (ROP) and between different stages of ROP when quantifying the associated vessel changes in width and tortuosity ..
  55. Lee B, Kim J, Heo H, Yu Y. Delayed onset atypical vitreoretinal traction band formation after an intravitreal injection of bevacizumab in stage 3 retinopathy of prematurity. Eye (Lond). 2012;26:903-9; quiz 910 pubmed publisher
    To report a series of patients who presented with an atypical retinal traction band, which was developed after an intravitreal injection of bevacizumab for stage 3 retinopathy of prematurity (ROP).
  56. Tasman W. Retinopathy of prematurity: do we still have a problem?: the Charles L. Schepens lecture. Arch Ophthalmol. 2011;129:1083-6 pubmed publisher
    To assess the present-day prevalence of retinopathy of prematurity (ROP) worldwide.
  57. Dubis A, Subramaniam C, Godara P, Carroll J, Costakos D. Subclinical macular findings in infants screened for retinopathy of prematurity with spectral-domain optical coherence tomography. Ophthalmology. 2013;120:1665-71 pubmed publisher
    To evaluate subclinical macular findings in premature patients at risk of retinopathy of prematurity (ROP) with the use of handheld spectral-domain optical coherence tomography (SD-OCT).
  58. Wani V, Uboweja A, Gani M, Al Kandari J, Kazem M, Al Naqeeb N, et al. Type I retinopathy of prematurity in infants with birth weight less than 1251 g: incidence and risk factors for its development in a nursery in Kuwait. Middle East Afr J Ophthalmol. 2013;20:66-71 pubmed publisher
    To report the rate of acute retinopathy of prematurity (ROP) and Type I ROP among infants with birth weight (BW) <1251 g and identify the risk factors for the development of Type I ROP.
  59. Jalali S, Balakrishnan D, Zeynalova Z, Padhi T, Rani P. Serious adverse events and visual outcomes of rescue therapy using adjunct bevacizumab to laser and surgery for retinopathy of prematurity. The Indian Twin Cities Retinopathy of Prematurity Screening database Report number 5. Arch Dis Child Fetal Neonatal Ed. 2013;98:F327-33 pubmed publisher
    To report serious adverse events and long-term outcomes of initial experience with intraocular bevacizumab in retinopathy of prematurity (ROP).
  60. Sood V, Chellani H, Arya S, Guliani B. Changing spectrum of retinopathy of prematurity (ROP) and variations among siblings of multiple gestation. Indian J Pediatr. 2012;79:905-10 pubmed publisher
    ..To assess the changing spectrum of ROP, and to compare the siblings of multiple gestations with regard to incidence and severity of ROP...
  61. Vanderveen D, Bremer D, Fellows R, Hardy R, Neely D, Palmer E, et al. Prevalence and course of strabismus through age 6 years in participants of the Early Treatment for Retinopathy of Prematurity randomized trial. J AAPOS. 2011;15:536-40 pubmed publisher
    To present strabismus data for children who participated in the Early Treatment for Retinopathy of Prematurity (ETROP) randomized trial.
  62. Houston S, Wykoff C, Berrocal A, Hess D, Murray T. Laser treatment for retinopathy of prematurity. Lasers Med Sci. 2013;28:683-92 pubmed publisher
    ..involves a complex coordination of events that may be affected by premature delivery, leading to retinopathy of prematurity (ROP), a potential blinding childhood disease...
  63. Hungi B, Vinekar A, Datti N, Kariyappa P, Braganza S, Chinnaiah S, et al. Retinopathy of Prematurity in a rural Neonatal Intensive Care Unit in South India--a prospective study. Indian J Pediatr. 2012;79:911-5 pubmed publisher
    To report the incidence, spectrum and treatment outcome of Retinopathy of Prematurity (ROP) in a rural neonatal nursery.