angioid streaks

Summary

Summary: Small breaks in the elastin-filled tissue of the retina.

Top Publications

  1. Ladas I, Georgalas I, Rouvas A, Gotsis S, Karagiannis D, Moschos M. Photodynamic therapy with verteporfin of choroidal neovascularization in angioid streaks: conventional versus early retreatment. Eur J Ophthalmol. 2005;15:69-73 pubmed
    ..the effectiveness of conventional photodynamic therapy with verteporfin (PDT) in a series of patients with macular choroidal neovascularization (CNV) due to angioid streaks and to compare it to the effectiveness of early PDT retreatment.
  2. Finger R, Charbel Issa P, Ladewig M, Gotting C, Szliska C, Scholl H, et al. Pseudoxanthoma elasticum: genetics, clinical manifestations and therapeutic approaches. Surv Ophthalmol. 2009;54:272-85 pubmed publisher
    ..patients exhibit characteristic lesions of the posterior segment of the eye including peau d'orange, angioid streaks, and choroidal neovascularisations, of the skin including soft, ivory-colored papules in a reticular pattern ..
  3. Brown S, Talks S, Needham S, Taylor A. Pseudoxanthoma elasticum: biopsy of clinically normal skin in the investigation of patients with angioid streaks. Br J Dermatol. 2007;157:748-51 pubmed
    ..Defects in Bruch's membrane produce angioid streaks on the retina but this appearance is not pathognomonic of PXE...
  4. Jurklies B, Bornfeld N, Schilling H. Photodynamic therapy using verteporfin for choroidal neovascularization associated with angioid streaks--long-term effects. Ophthalmic Res. 2006;38:209-17 pubmed
    To investigate the safety and efficacy of photodynamic therapy with verteporfin (PDT) in patients with choroidal neovascularization associated with angioid streaks (CNVAS).
  5. Shah M, Amoaku W. Intravitreal ranibizumab for the treatment of choroidal neovascularisation secondary to angioid streaks. Eye (Lond). 2012;26:1194-8 pubmed publisher
    To assess the medium to long-term efficacy and safety of intravitreal ranibizumab for the treatment of choroidal neovascularisation (CNV) secondary to angioid streaks (AS).
  6. Zebardast N, Adelman R. Intravitreal ranibizumab for treatment of choroidal neovascularization secondary to angioid streaks in pseudoxanthoma elasticum: five-year follow-up. Semin Ophthalmol. 2012;27:61-4 pubmed publisher
    To report on the five-year follow-up of ranibizumab therapy for choroidal neovascularization (CNV) secondary to angioid streaks (AS) in pseudoxanthoma elasticum (PXE).
  7. Artunay O, Yuzbasioglu E, Rasier R, Sengul A, Senel A, Bahcecioglu H. Combination treatment with intravitreal injection of ranibizumab and reduced fluence photodynamic therapy for choroidal neovascularization secondary to angioid streaks: preliminary clinical results of 12-month follow-up. Retina. 2011;31:1279-86 pubmed publisher
    To evaluate combination treatment with intravitreal ranibizumab injection and reduced fluence photodynamic therapy for choroidal neovascularization associated with angioid streaks.
  8. Menchini U, Virgili G, Introini U, Bandello F, Ambesi Impiombato M, Pece A, et al. Outcome of choroidal neovascularization in angioid streaks after photodynamic therapy. Retina. 2004;24:763-71 pubmed
    To evaluate the visual and anatomic outcomes of photodynamic therapy for choroidal neovascularization (CNV) in patients with angioid streaks.
  9. Tanaka M, Shimada H, Haruyama M, Lee Z, Nakajima M, Yuzawa M. [Surgical removal of choroidal neovascularization in angioid streaks]. Nippon Ganka Gakkai Zasshi. 2003;107:440-4 pubmed
    All the studies so far on surgical removal of choroidal neovascularization (CNV) in angioid streaks(AS) were conducted on a small number of cases. Therefore, a definitive evaluation of the surgical method was not available...

More Information

Publications79

  1. Derriman L, Marshall J, Moorman C, Downes S. The use of intravitreal bevacizumab to treat choroidal neovascular membranes (CNVMs). Retina. 2008;28:910; author reply 910-1 pubmed publisher
  2. Shaikh S, Ruby A, Williams G. Photodynamic therapy using verteporfin for choroidal neovascularization in angioid streaks. Am J Ophthalmol. 2003;135:1-6 pubmed
    To evaluate the efficacy of photodynamic therapy with verteporfin in the management of choroidal neovascularization (CNV) associated with angioid streaks.
  3. Schiano Lomoriello D, Parravano M, Chiaravalloti A, Varano M. Choroidal neovascularization in angioid streaks and pseudoxanthoma elasticum: 1 year follow-up. Eur J Ophthalmol. 2009;19:151-3 pubmed
    To report the efficacy of intravitreal injection of bevacizumab 1.25 mg (IVB) in the treatment of choroidal neovascularization (CNV) secondary to angioid streaks (AS).
  4. Lommatzsch A, Spital G, Trieschmann M, Pauleikhoff D. [Intraocular application of bevacizumab for the treatment of choroidal neovascularization secondary to angioid streaks]. Ophthalmologe. 2007;104:325-8 pubmed
    b>Angioid streaks are the typical ophthalmological manifestation of the systemic disease pseudoxanthoma elasiticum. Fundoscopy reveals angioid streaks as irregular dark brownish lines radiating from the area around the optic disc...
  5. Aessopos A, Floudas C, Kati M, Tsironi M, Giakoumi X, Livir Rallatos C, et al. Loss of vision associated with angioid streaks in beta-thalassemia intermedia. Int J Hematol. 2008;87:35-8 pubmed publisher
    ..We report here two patients with beta-thalassemia intermedia, who presented with severe visual acuity impairment associated with angioid streaks, the typical ocular manifestation of PXE.
  6. Sachdev N, Vishwanathan K, Gupta V, Singh R, Gupta A. Intravitreal bevacizumab (Avastin) in choroidal neovascular membrane in angioid streaks. Indian J Ophthalmol. 2007;55:457-8 pubmed
    b>Angioid streaks are crack-like dehiscences in the Bruch's membrane, which predispose to the development of a choroidal neovascular membrane (CNVM) that carries a poor visual outcome...
  7. Bhatnagar P, Freund K, Spaide R, Klancnik J, Cooney M, Ho I, et al. Intravitreal bevacizumab for the management of choroidal neovascularization in pseudoxanthoma elasticum. Retina. 2007;27:897-902 pubmed
    To determine the results of intravitreal bevacizumab injections for the management of choroidal neovascularization (CNV) in patients with pseudoxanthoma elasticum (PXE)-associated angioid streaks.
  8. Gliem M, Finger R, Fimmers R, Brinkmann C, Holz F, Charbel Issa P. Treatment of choroidal neovascularization due to angioid streaks: a comprehensive review. Retina. 2013;33:1300-14 pubmed publisher
    To evaluate different therapies for choroidal neovascularization (CNV) due to angioid streaks (AS).
  9. Karacorlu M, Karacorlu S, Ozdemir H, Mat C. Photodynamic therapy with verteporfin for choroidal neovascularization in patients with angioid streaks. Am J Ophthalmol. 2002;134:360-6 pubmed
    To evaluate safety and efficacy of photodynamic therapy with verteporfin for subfoveal choroidal neovascularization associated with angioid streaks.
  10. Arias L, Pujol O, Rubio M, Caminal J. Long-term results of photodynamic therapy for the treatment of choroidal neovascularization secondary to angioid streaks. Graefes Arch Clin Exp Ophthalmol. 2006;244:753-7 pubmed
    To evaluate the anatomic-functional results and complications associated with the use of photodynamic therapy (PDT) with verteporfin in the treatment of choroidal neovascularization (CNV) secondary to angioid streaks (AS).
  11. Zweifel S, Imamura Y, Freund K, Spaide R. Multimodal fundus imaging of pseudoxanthoma elasticum. Retina. 2011;31:482-91 pubmed publisher
    ..To investigate spectral domain optical coherence tomography and autofluorescence findings in eyes with pseudoxanthoma elasticum...
  12. Prabhu V, Morris R, Shah P, Narendran V. Combination treatment of low fluence photodynamic therapy and intravitreal ranibizumab for choroidal neovascular membrane secondary to angioid streaks in Paget's disease - 12 month results. Indian J Ophthalmol. 2011;59:306-8 pubmed publisher
    b>Angioid streaks also called Knapp striae are small breaks in the Bruch's membrane and have been reported with a host of systemic diseases...
  13. Teixeira A, Moraes N, Farah M, Bonomo P. Choroidal neovascularization treated with intravitreal injection of bevacizumab (Avastin) in angioid streaks. Acta Ophthalmol Scand. 2006;84:835-6 pubmed
  14. Sato N, Nakayama T, Mizutani Y, Yuzawa M. Novel mutations of ABCC6 gene in Japanese patients with Angioid streaks. Biochem Biophys Res Commun. 2009;380:548-53 pubmed publisher
    b>Angioid streaks (AS) are eye abnormalities caused by breaks in Bruch's membrane. The condition is often associated with pseudoxanthoma elasticum (PXE)...
  15. Wiegand T, Rogers A, McCabe F, Reichel E, Duker J. Intravitreal bevacizumab (Avastin) treatment of choroidal neovascularisation in patients with angioid streaks. Br J Ophthalmol. 2009;93:47-51 pubmed publisher
    To evaluate the safety and efficacy of intravitreal bevacizumab (Avastin) as treatment for choroidal neovascularisation (CNV) associated with angioid streaks
  16. Neri P, Salvolini S, Mariotti C, Mercanti L, Celani S, Giovannini A. Long-term control of choroidal neovascularisation secondary to angioid streaks treated with intravitreal bevacizumab (Avastin). Br J Ophthalmol. 2009;93:155-8 pubmed publisher
    To evaluate the efficacy of intravitreal bevacizumab (IB) in the long-term control of subfoveal choroidal neovascularisation (CNV) associated with angioid streaks (AS).
  17. Mimoun G, Tilleul J, Leys A, Coscas G, Soubrane G, Souied E. Intravitreal ranibizumab for choroidal neovascularization in angioid streaks. Am J Ophthalmol. 2010;150:692-700.e1 pubmed publisher
    To analyze retrospectively the efficacy of intravitreal ranibizumab injections for the management of choroidal neovascularization (CNV) in patients with angioid streaks.
  18. Sawa M, Gomi F, Tsujikawa M, Sakaguchi H, Tano Y. Long-term results of intravitreal bevacizumab injection for choroidal neovascularization secondary to angioid streaks. Am J Ophthalmol. 2009;148:584-590.e2 pubmed publisher
    To investigate the long-term efficacy of intravitreal injections of bevacizumab (Avastin; Genentech Inc, South San Francisco, California, USA) for choroidal neovascularization (CNV) secondary to angioid streaks.
  19. Finger R, Charbel Issa P, Hendig D, Scholl H, Holz F. Monthly ranibizumab for choroidal neovascularizations secondary to angioid streaks in pseudoxanthoma elasticum: a one-year prospective study. Am J Ophthalmol. 2011;152:695-703 pubmed publisher
    To evaluate the efficacy and safety of monthly intravitreal ranibizumab for the treatment of choroidal neovascularizations (CNV) secondary to angioid streaks (AS) in pseudoxanthoma elasticum (PXE).
  20. Roth D, Estafanous M, Lewis H. Macular translocation for subfoveal choroidal neovascularization in angioid streaks. Am J Ophthalmol. 2001;131:390-2 pubmed
    To report a case of visual improvement after macular translocation performed for a subfoveal choroidal neovascular membrane in a patient with pseudoxanthoma elasticum and angioid streaks.
  21. Mennel S, Schmidt J, Meyer C. Therapeutic strategies in choroidal neovascularizations secondary to angioid streaks. Am J Ophthalmol. 2003;136:580-2; author reply 582-3 pubmed
  22. Sickenberg M, Schmidt Erfurth U, Miller J, Pournaras C, Zografos L, Piguet B, et al. A preliminary study of photodynamic therapy using verteporfin for choroidal neovascularization in pathologic myopia, ocular histoplasmosis syndrome, angioid streaks, and idiopathic causes. Arch Ophthalmol. 2000;118:327-36 pubmed
    ..photodynamic therapy with verteporfin for choroidal neovascularization (CNV) not related to age-related macular degeneration (AMD), including pathologic myopia, the ocular histoplasmosis syndrome, angioid streaks, and idiopathic causes.
  23. Browning A, Amoaku W, Chung A, Ghanchi F, Harding S, Musadiq M, et al. Photodynamic therapy for angioid streaks. Ophthalmology. 2007;114:1592 pubmed
  24. Heimann H, Gelisken F, Wachtlin J, Wehner A, Völker M, Foerster M, et al. Photodynamic therapy with verteporfin for choroidal neovascularization associated with angioid streaks. Graefes Arch Clin Exp Ophthalmol. 2005;243:1115-23 pubmed
    Choroidal neovascularizations (CNV) is the major cause of significant visual loss in patients with angioid streaks. We evaluated the functional and morphological outcome of Verteporfin photodynamic therapy (PDT) in the treatment of these ..
  25. Finger R, Charbel Issa P, Schmitz Valckenberg S, Holz F, Scholl H. Long-term effectiveness of intravitreal bevacizumab for choroidal neovascularization secondary to angioid streaks in pseudoxanthoma elasticum. Retina. 2011;31:1268-78 pubmed publisher
    ..To investigate the long-term effectiveness of intravitreal bevacizumab for treating active choroidal neovascularizations in pseudoxanthoma elasticum (PXE)...
  26. Browning A, Chung A, Ghanchi F, Harding S, Musadiq M, Talks S, et al. Verteporfin photodynamic therapy of choroidal neovascularization in angioid streaks: one-year results of a prospective case series. Ophthalmology. 2005;112:1227-31 pubmed
    To report the 12-month results on the use of verteporfin photodynamic therapy (PDT) in the treatment of choroidal neovascularization (CNV) secondary to angioid streaks.
  27. Aras C, Baserer T, Yolar M, Yetik H, Artunay O, Guzel H, et al. Two cases of choroidal neovascularization treated with transpupillary thermotherapy in angioid streaks. Retina. 2004;24:801-3 pubmed
  28. Pandolfo A, Verrastro G, Piccolino F. Retinal hemorrhages following indirect ocular trauma in a patient with angioid streaks. Retina. 2002;22:830-1 pubmed
  29. Donati M, Virgili G, Bini A, Giansanti F, Rapizzi E, Giacomelli G, et al. Intravitreal bevacizumab (Avastin) for choroidal neovascularization in angioid streaks: a case series. Ophthalmologica. 2009;223:24-7 pubmed publisher
  30. Rinaldi M, dell Omo R, Romano M, Chiosi F, Cipollone U, Costagliola C. Intravitreal bevacizumab for choroidal neovascularization secondary to angioid streaks. Arch Ophthalmol. 2007;125:1422-3 pubmed
  31. Ellabban A, Tsujikawa A, Matsumoto A, Ogino K, Hangai M, Ooto S, et al. Macular choroidal thickness and volume in eyes with angioid streaks measured by swept source optical coherence tomography. Am J Ophthalmol. 2012;153:1133-43.e1 pubmed publisher
    To study the mean choroidal thickness and volume of the macula in eyes with angioid streaks using swept source optical coherence tomography (OCT) in the 1050-nm wavelength range.
  32. Ladas I, Kotsolis A, Ladas D, Niskopoulou M, Georgalas I, Papakonstantinou D, et al. Intravitreal ranibizumab treatment of macular choroidal neovascularization secondary to angioid streaks: one-year results of a prospective study. Retina. 2010;30:1185-9 pubmed publisher
    The purpose of this study was to evaluate the efficacy of intravitreal ranibizumab in eyes with macular choroidal neovascularization secondary to angioid streaks.
  33. Iacono P, Battaglia Parodi M, La Spina C, Bandello F. Intravitreal Bevacizumab for Nonsubfoveal Choroidal Neovascularization Associated With Angioid Streaks: 3-Year Follow-up Study. Am J Ophthalmol. 2016;165:174-8 pubmed publisher
    ..bevacizumab injections in the treatment of nonsubfoveal choroidal neovascularization (CNV) associated with angioid streaks (AS) in a 3-year follow-up study. Noncomparative, interventional, prospective case series...
  34. Germain D. Pseudoxanthoma elasticum. Orphanet J Rare Dis. 2017;12:85 pubmed publisher
    ..Dystrophic calcification of Bruch's membrane, revealed by angioid streaks, may trigger choroidal neovascularization and, ultimately, loss of central vision and blindness in late-stage ..
  35. Liaska A, Petrou P, Georgakopoulos C, Diamanti R, Papaconstantinou D, Kanakis M, et al. ?-Thalassemia and ocular implications: a systematic review. BMC Ophthalmol. 2016;16:102 pubmed publisher
    ..Ocular fundus abnormalities characteristic of pseudoxanthoma elasticum (PXE), including peau d'orange, angioid streaks, pattern dystrophy-like changes, and optic disc drusen are a consistent finding in seven studies...
  36. Luviano D, Benz M, Kim R, Fish R, Wong T, Kegley E, et al. Selected clinical comparisons of spectral domain and time domain optical coherence tomography. Ophthalmic Surg Lasers Imaging. 2009;40:325-8 pubmed
    ..These cases include one of angioid streaks, two of juxtafoveal telangiectasia, and one of age-related macular degeneration...
  37. Abujamra S, Negretto A, Saraceno J, Oliveira T, Gomes A. [Angioid streaks: fundoscopic analysis of 317 cases]. Arq Bras Oftalmol. 2008;71:819-21 pubmed
    To evaluate the presence of choroidal neovascularization (CN) and their sequels in patient bearing angioid streaks (AE)...
  38. Gorin M, Paul T, Rader D. Angioid streaks associated with abetalipoproteinemia. Ophthalmic Genet. 1994;15:151-9 pubmed
    b>Angioid streaks were observed in two patients with abetalipoproteinemia...
  39. Shoumnalieva Ivanova V, Tanev I, Zdravkov Y, Monov S, Shumnalieva R. Angioid streaks in aagenaes syndrome. Int Ophthalmol. 2017;37:1065-1068 pubmed publisher
    ..The locus, LCS1, was mapped to a 6.6 cM region on chromosome 15. Angioid streaks are visible irregular crack-like dehiscences in bruch's membrane that are associated with atrophic ..
  40. Schoenberger S, Agarwal A. Geographic chorioretinal atrophy in pseudoxanthoma elasticum. Am J Ophthalmol. 2013;156:715-23 pubmed publisher
    ..Progression is similar to age-related macular degeneration. Recognition of this feature is important, especially if therapies to slow or reverse geographic atrophy become available. ..
  41. Le Scanff J, Seve P, Dalle S, Kodjikian L, Thomas L, Broussolle C. Coexisting pseudoxanthoma elasticum and lupus erythematosus: report of two cases. Int J Dermatol. 2007;46:622-4 pubmed
    ..Given the ocular and vascular complications of PXE, clinicians who treat patients with lupus should be aware of this possible association. ..
  42. McBrayer G, Semes L, Stephens G. Angioid streaks and AC hemoglobinopathy--a newly discovered association. J Am Optom Assoc. 1993;64:250-3 pubmed
    ..b>Angioid streaks in the ocular fundus represent a progressive, bilateral, degenerative disorder characterized by breaks in ..
  43. van Meurs T, van Hagen J, van de Scheur M, Vermaat H, Ruijs M, van den Hoogenband H, et al. Classic pseudoxanthoma elasticum in a patient with sickle cell disease. J Am Acad Dermatol. 2007;56:170-1 pubmed
  44. Miki K, Yuri T, Takeda N, Takehana K, Iwasaka T, Tsubura A. An autopsy case of pseudoxanthoma elasticum: histochemical characteristics. Med Mol Morphol. 2007;40:172-7 pubmed
    ..was 58 years old, in response to her visual disturbance a funduscopic examination was performed, revealing angioid streaks, and skin biopsy identified a characteristic pseudoxanthoma elasticum (PXE) lesion...
  45. Figurska M. [Photodynamic therapy for treatment choroidal neovascularization in angioid streaks--case report]. Klin Oczna. 2007;109:55-9 pubmed
    ..the effects of photodynamic therapy for treatment of bilateral macular choroidal neovascularization in angioid streaks during 16 months period. 50 years old man has one PDT in the right eye and three in the left eye...
  46. Nakagawa S, Yamashiro K, Tsujikawa A, Otani A, Tamura H, Ooto S, et al. The time course changes of choroidal neovascularization in angioid streaks. Retina. 2013;33:825-33 pubmed publisher
    To assess the clinical course of choroidal neovascularization (CNV) in patients with angioid streaks using optical coherence tomography and fluorescein angiography/indocyanine green angiography...
  47. Sawa M, Ober M, Freund K, Spaide R. Fundus autofluorescence in patients with pseudoxanthoma elasticum. Ophthalmology. 2006;113:814-20.e2 pubmed
    ..Of the 16 eyes of the 8 patients, all had abnormalities typical of pseudoxanthoma elasticum, including angioid streaks in 14, peau d'orange in 4, and choroidal neovascularization in 11...
  48. Verbraak F. Antivascular endothelial growth factor treatment in pseudoxanthoma elasticum patients. Dev Ophthalmol. 2010;46:96-106 pubmed publisher
    ..with pseudoxanthoma elasticum, an autosomal recessive disease, shows several lesions, like peau d'orange, angioid streaks, comet lesions, and paired hyperpigmented smudges...
  49. Tsui I, Fuchs B, Chou C, Chang S, Tsang S. Non-vascular vision loss in pseudoxanthoma elasticum. Doc Ophthalmol. 2008;117:65-7 pubmed
    Pseudoxanthoma elasticum patients with angioid streaks are well-known to have acute vision loss due to choroidal bleeding. However, chronic vision loss due to macular atrophy is less well characterized...
  50. Munteanu M, Chercota V. [Optic nerve drusen and angioid streaks in pseudoxanthoma elasticum]. Oftalmologia. 2007;51:99-102 pubmed
    The clinical study presents the association between optic disc drusen and angioid streaks in the context of pseudoxanthoma elasticum, in 8.5% (4 from 47) of the cases...
  51. Tugcu B, Sezer T, Elbay A, Ozdemir H. Angioid streaks in a case of Camurati-Engelmann disease. Indian J Ophthalmol. 2017;65:628-630 pubmed publisher
    ..We report a case of CED showing angioid streaks (ASs) in both fundi with no macular involvement and discuss the possible theories of the pathogenesis of AS ..
  52. Karadimas P, Bouzas E. Photodynamic therapy with verteporfin for choroidal neovascularization complicating angioid streaks. Ophthalmic Surg Lasers Imaging. 2004;35:78-80 pubmed
  53. Chung A, Gauba V, Ghanchi F. Photodynamic therapy (PDT) using verteporfin for juxtafoveal choroidal neovascularisation (CNV) in angioid streaks (AS) associated with pseudoxanthoma elasticum: 40 months results. Eye (Lond). 2006;20:629-31 pubmed
  54. Kovach J, Schwartz S, Hickey M, Puliafito C. Thirty-two month follow-up of successful treatment of choroidal neovascularization from angioid streaks with intravitreal bevacizumab. Ophthalmic Surg Lasers Imaging. 2009;40:77-9 pubmed
    A patient presented with subfoveal choroidal neovascularization associated with angioid streaks and was treated with three intravitreal injections of off-label bevacizumab (1.25 mg) in the right eye...
  55. Morillo M, Mora J, Soler A, García Campos J, García Fernández I, Sanchez P, et al. [Retinal autofluorescence imaging in patients with pseudoxanthoma elasticum]. Arch Soc Esp Oftalmol. 2011;86:8-15 pubmed publisher
    ..To evaluate the autofluorescence findings in patients diagnosed with pseudoxanthoma elasticum...
  56. Lee J, Nam W, Kim H. Photodynamic therapy with verteporfin for choroidal neovascularization in patients with angioid streaks. Korean J Ophthalmol. 2007;21:142-5 pubmed
    To evaluate the functional and anatomic outcomes of photodynamic therapy (PDT) for choroidal neovascularization (CNV) in patients with angioid streaks.
  57. Teixeira A, Mattos T, Velletri R, Teixeira R, Freire J, Moares N, et al. Clinical course of choroidal neovascularization secondary to angioid streaks treated with intravitreal bevacizumab. Ophthalmic Surg Lasers Imaging. 2010;41:546-9 pubmed publisher
    To evaluate visual acuity and anatomical outcomes of choroidal neovascularization (CNV) associated with angioid streaks after treatment with intravitreal bevacizumab injections.
  58. Yenerel N, Dinc U, Gorgun E. A case of sterile endophthalmitis after repeated intravitreal bevacizumab injection. J Ocul Pharmacol Ther. 2008;24:362-3 pubmed publisher
    The aim of this study was to describe a case of sterile endophthalmitis after repeated intravitreal bevacizumab injections for the treatment of choroidal neovascularization secondary to angioid streaks.
  59. Vadalà M, Pece A, Cipolla S, Monteleone C, Ricci F, Boscia F, et al. Angioid streak-related choroidal neovascularization treated by intravitreal ranibizumab. Retina. 2010;30:903-7 pubmed publisher
    The purpose of this study was to report the visual outcome of intravitreal therapy with ranibizumab of choroidal neovascularization secondary to angioid streaks after 1-year follow-up.
  60. el Matri L, Kort F, Bouraoui R, Karim B, Chebil A, Chaker N. Intravitreal bevacizumab for the treatment of choroidal neovascularization secondary to angioid streaks: one year of follow-up. Acta Ophthalmol. 2011;89:641-6 pubmed publisher
    To evaluate the efficacy and safety of intravitreal bevacizumab at one year follow-up, for the treatment of choroidal neovascularization (CNV) associated with angioid streaks.
  61. Nitschke Y, Baujat G, Botschen U, Wittkampf T, du Moulin M, Stella J, et al. Generalized arterial calcification of infancy and pseudoxanthoma elasticum can be caused by mutations in either ENPP1 or ABCC6. Am J Hum Genet. 2012;90:25-39 pubmed publisher
    ..biallelic ENPP1 mutations developed typical signs of PXE between 5 and 8 years of age; these signs included angioid streaks and pseudoxanthomatous skin lesions. In 28 patients, no disease-causing ENPP1 mutation was found...
  62. Zaraa I, Cherif F, Abdelmoula F, Mokni M, Ben Tekaya N, Haouet S, et al. [Pseudoxanthoma elasticum: a report of 11 cases]. Tunis Med. 2006;84:296-300 pubmed
    ..Pseudoxanthoma elasticum (PXE) is an inherited disorder of elastic tissue with many systemic manifestations..
  63. Agarwal A, Patel P, Adkins T, Gass J. Spectrum of pattern dystrophy in pseudoxanthoma elasticum. Arch Ophthalmol. 2005;123:923-8 pubmed
    ..To study the prevalence, type, and features of pattern dystrophy in patients with pseudoxanthoma elasticum (PXE)...
  64. Holekamp N, Thomas M, Pearson A. The safety profile of long-term, high-dose intraocular corticosteroid delivery. Am J Ophthalmol. 2005;139:421-8 pubmed
    ..To report the feasibility and safety profile of 2-mg and 6-mg fluocinolone acetonide implants after long-term follow-up in eyes with choroidal neovascularization (CNV)...
  65. Miwa K, Higashikata T, Mabuchi H. Intravascular ultrasound findings of coronary wall morphology in a patient with pseudoxanthoma elasticum. Heart. 2004;90:e61 pubmed
    ..These findings may reflect the earlier stage of coronary artery disease caused by PXE before calcification of the internal elastic laminae...
  66. Utani A, Tanioka M, Yamamoto Y, Taki R, Araki E, Tamura H, et al. Relationship between the distribution of pseudoxanthoma elasticum skin and mucous membrane lesions and cardiovascular involvement. J Dermatol. 2010;37:130-6 pubmed publisher
    ..All patients had angioid streaks (AS) and positive pathological findings...
  67. Aessopos A, Farmakis D, Loukopoulos D. Elastic tissue abnormalities in inherited haemolytic syndromes. Eur J Clin Invest. 2002;32:640-2 pubmed
  68. Aessopos A, Farmakis D, Loukopoulos D. Elastic tissue abnormalities resembling pseudoxanthoma elasticum in beta thalassemia and the sickling syndromes. Blood. 2002;99:30-5 pubmed
    ..Because several organ systems are involved, each medical specialty should be aware of the phenomenon. This coexistence, on the other hand, introduces a novel pathogenetic aspect of PXE and an important research challenge...
  69. Zhu Q, Ziemssen F, Henke Fahle S, Tatar O, Szurman P, Aisenbrey S, et al. Vitreous levels of bevacizumab and vascular endothelial growth factor-A in patients with choroidal neovascularization. Ophthalmology. 2008;115:1750-5, 1755.e1 pubmed publisher
    ..To investigate the vitreous levels of bevacizumab and vascular endothelial growth factor-A (VEGF-A) after intravitreal injection of the drug in patients with choroidal neovascularization (CNV)...
  70. Kerr N, Cassinelli H, DiMeglio L, Tau C, Tuysuz B, Cundy T, et al. Ocular manifestations of juvenile Paget disease. Arch Ophthalmol. 2010;128:698-703 pubmed publisher
    ..To determine the prevalence and spectrum of retinal changes in juvenile Paget disease...