retinal diseases

Summary

Summary: Diseases involving the RETINA.

Top Publications

  1. Sharon D, Al Hamdani S, Engelsberg K, Mizrahi Meissonnier L, Obolensky A, Banin E, et al. Ocular phenotype analysis of a family with biallelic mutations in the BEST1 gene. Am J Ophthalmol. 2014;157:697-709.e1-2 pubmed publisher
    ..To investigate the genetic cause and perform a comprehensive clinical analysis of a Danish family with autosomal recessive bestrophinopathy; to investigate whether Bestrophin may be expressed in normal human retina...
  2. Maamari R, Keenan J, Fletcher D, Margolis T. A mobile phone-based retinal camera for portable wide field imaging. Br J Ophthalmol. 2014;98:438-41 pubmed publisher
    Digital fundus imaging is used extensively in the diagnosis, monitoring and management of many retinal diseases. Access to fundus photography is often limited by patient morbidity, high equipment cost and shortage of trained personnel...
  3. Dhingra A, Fina M, Neinstein A, Ramsey D, Xu Y, Fishman G, et al. Autoantibodies in melanoma-associated retinopathy target TRPM1 cation channels of retinal ON bipolar cells. J Neurosci. 2011;31:3962-7 pubmed publisher
    ..We conclude that the vision of at least some patients with MAR is compromised due to autoantibody-mediated inactivation of the TRPM1 channel. ..
  4. Siegert S, Cabuy E, Scherf B, Kohler H, Panda S, Le Y, et al. Transcriptional code and disease map for adult retinal cell types. Nat Neurosci. 2012;15:487-95, S1-2 pubmed publisher
  5. Miyadera K, Acland G, Aguirre G. Genetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studies. Mamm Genome. 2012;23:40-61 pubmed publisher
    ..Different forms of retinal diseases occur in specific breed(s) caused by mutations segregating within each isolated breeding population...
  6. Wohl S, Schmeer C, Isenmann S. Neurogenic potential of stem/progenitor-like cells in the adult mammalian eye. Prog Retin Eye Res. 2012;31:213-42 pubmed publisher
    ..Finally, we discuss therapeutic potential of these cells with respect to cell replacement strategies and putative clinical application...
  7. Stefanova N, Fursova A, Sarsenbaev K, Kolosova N. Effects of Cistanche deserticola on behavior and signs of cataract and retinopathy in senescence-accelerated OXYS rats. J Ethnopharmacol. 2011;138:624-32 pubmed publisher
    ..Cistanche deserticola (?D) has been traditionally used in the Chinese medicine as a tonic, vasodilator and neuroprotective agent...
  8. Muthaian R, Minhas G, Anand A. Pathophysiology of stroke and stroke-induced retinal ischemia: emerging role of stem cells. J Cell Physiol. 2012;227:1269-79 pubmed publisher
    ..In this review, we highlight the advantages and limitations of this approach with a focus on key observations from preclinical animal studies and clinical trials. Further research, especially on treatment with EPCs is warranted. ..
  9. Garrioch R, Langlo C, Dubis A, Cooper R, Dubra A, Carroll J. Repeatability of in vivo parafoveal cone density and spacing measurements. Optom Vis Sci. 2012;89:632-43 pubmed publisher
    ..Separate studies addressing intersession repeatability and interobserver reliability are also needed. ..

More Information

Publications69

  1. Otto E, Hurd T, Airik R, Chaki M, Zhou W, Stoetzel C, et al. Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nat Genet. 2010;42:840-50 pubmed publisher
    ..This work identifies loss of SDCCAG8 function as a cause of a retinal-renal ciliopathy and validates exome capture analysis for broadly heterogeneous single-gene disorders. ..
  2. Bader Meunier B, Monnet D, Barnerias C, Halphen I, Lambot Juhan K, Chalumeau M, et al. Thrombotic microangiopathy and Purtscher-like retinopathy as a rare presentation of juvenile dermatomyositis. Pediatrics. 2012;129:e821-4 pubmed publisher
    ..This report emphasizes that early recognition of TTP and prompt plasmapheresis are important in a child with severe juvenile dermatomyositis associated with thrombocytopenia...
  3. Schatz A, Wilke R, Strasser T, Gekeler F, Messias A, Zrenner E. Assessment of "non-recordable" electroretinograms by 9 Hz flicker stimulation under scotopic conditions. Doc Ophthalmol. 2012;124:27-39 pubmed publisher
    ..Thus, we believe this protocol can be used to record ERG potentials in patients with advanced retinal diseases and in the evaluation of potential treatments for these patients...
  4. Rossi S, Testa F, Li A, Iorio V, Zhang J, Gesualdo C, et al. An atypical form of Bietti crystalline dystrophy. Ophthalmic Genet. 2011;32:118-21 pubmed publisher
    ..This suggests the existence of less severe forms of BCD related to relatively mild CYP4V2 mutations. ..
  5. Errera M, Kohly R, da Cruz L. Pregnancy-associated retinal diseases and their management. Surv Ophthalmol. 2013;58:127-42 pubmed publisher
    Pregnancy-associated retinal diseases are conditions that may occur uniquely in pregnancy or, more commonly, general conditions that may worsen or alter during pregnancy as a result of hematologic, hormonal, metabolic, cardiovascular, and ..
  6. Hewing N, Weskamp G, Vermaat J, Farage E, Glomski K, Swendeman S, et al. Intravitreal injection of TIMP3 or the EGFR inhibitor erlotinib offers protection from oxygen-induced retinopathy in mice. Invest Ophthalmol Vis Sci. 2013;54:864-70 pubmed publisher
  7. Horton M, Thompson K. Lipemia retinalis preceding acute pancreatitis. Optometry. 2011;82:475-80 pubmed publisher
    ..It may also be the only systemic sign present if triglycerides are acutely elevated in an asymptomatic patient. It may be the harbinger of more serious complications, such as acute pancreatitis and coronary artery disease...
  8. Vasconcelos Santos D, Dodds E, Orefice F. Review for disease of the year: differential diagnosis of ocular toxoplasmosis. Ocul Immunol Inflamm. 2011;19:171-9 pubmed publisher
    ..Ocular toxoplasmosis has multiple clinical manifestations, which partially overlap with those of other entities and these should be carefully considered when making the differential diagnosis, particularly in less typical cases...
  9. Miguel A, Henriques F, Azevedo L, Loureiro A, Maberley D. Systematic review of Purtscher's and Purtscher-like retinopathies. Eye (Lond). 2013;27:1-13 pubmed publisher
    ..2) To compare visual acuity (VA) of patients receiving corticosteroids for PuR compared with observation...
  10. Wang F, Yu S, Liu K, Chen F, Song Z, Zhang X, et al. Acute intraocular inflammation caused by endotoxin after intravitreal injection of counterfeit bevacizumab in Shanghai, China. Ophthalmology. 2013;120:355-61 pubmed publisher
    ..To describe an outbreak of intraocular inflammation caused by endotoxin-contaminated counterfeit bevacizumab in China...
  11. Wurm A, Iandiev I, Uhlmann S, Wiedemann P, Reichenbach A, Bringmann A, et al. Effects of ischemia-reperfusion on physiological properties of Müller glial cells in the porcine retina. Invest Ophthalmol Vis Sci. 2011;52:3360-7 pubmed publisher
    ..A viable animal model for human ischemic events should display similarities in eye size and retinal blood supply. Therefore, pigs were used in this investigation of physiological alterations in Müller cells after ischemia-reperfusion...
  12. Ogishima H, Nakamura S, Nakanishi T, Imai S, Kakino M, Ishizuka F, et al. Ligation of the pterygopalatine and external carotid arteries induces ischemic damage in the murine retina. Invest Ophthalmol Vis Sci. 2011;52:9710-20 pubmed publisher
    ..This study aimed to characterize the functional and morphologic changes in a murine model of ocular ischemic disease caused by vascular occlusion...
  13. Marmor M, Kellner U, Lai T, Lyons J, Mieler W. Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy. Ophthalmology. 2011;118:415-22 pubmed publisher
    ..No treatment exists as yet for this disorder, so it is imperative that patients and their physicians be aware of the best practices for minimizing toxic damage...
  14. Michaelides M, Stover N, Francis P, Weleber R. Retinal toxicity associated with hydroxychloroquine and chloroquine: risk factors, screening, and progression despite cessation of therapy. Arch Ophthalmol. 2011;129:30-9 pubmed publisher
    ..To report the detailed clinical findings of patients with retinal toxicity that developed secondary to the use of hydroxychloroquine sulfate (n = 13), chloroquine phosphate (n = 2), or a combination of the agents (n = 1)...
  15. Boon C, van den Born L, Visser L, Keunen J, Bergen A, Booij J, et al. Autosomal recessive bestrophinopathy: differential diagnosis and treatment options. Ophthalmology. 2013;120:809-20 pubmed publisher
    ..To describe the clinical and genetic characteristics of patients with autosomal recessive bestrophinopathy (ARB)...
  16. Yokota H, Narayanan S, Zhang W, Liu H, Rojas M, Xu Z, et al. Neuroprotection from retinal ischemia/reperfusion injury by NOX2 NADPH oxidase deletion. Invest Ophthalmol Vis Sci. 2011;52:8123-31 pubmed publisher
    ..The aim of this study was to determine whether NOX2, one of the homologs of NADPH oxidase, plays a role in neuronal cell death during retinal ischemia...
  17. Rey Funes M, Ibarra M, Dorfman V, Serrano J, Fernández A, Martinez Murillo R, et al. Hypothermia prevents nitric oxide system changes in retina induced by severe perinatal asphyxia. J Neurosci Res. 2011;89:729-43 pubmed publisher
    ..HYP prevented all the changes observed in PA rats. Although the NO system displays changes induced by hypoxia-ischemia, hypothermia application shows a strong protective effect...
  18. Barakat D, Dvoriantchikova G, Ivanov D, Shestopalov V. Astroglial NF-?B mediates oxidative stress by regulation of NADPH oxidase in a model of retinal ischemia reperfusion injury. J Neurochem. 2012;120:586-97 pubmed publisher
    ..Collectively, our results suggest that astroglial NF-?B-regulated PHOX activity is a crucial toxicity pathway in the pathogenesis of retinal IR injury...
  19. Barot M, Gokulgandhi M, Mitra A. Mitochondrial dysfunction in retinal diseases. Curr Eye Res. 2011;36:1069-77 pubmed publisher
    ..review highlights the role of mitochondrial dysfunction originating from oxidative stress in the etiology of retinal diseases including diabetic retinopathy, glaucoma and age-related macular degeneration (AMD)...
  20. Zhang K, Zhang L, Weinreb R. Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma. Nat Rev Drug Discov. 2012;11:541-59 pubmed publisher
    ..This Review discusses the current state of ocular drug therapy and highlights future therapeutic opportunities...
  21. Preising M, Pasquay C, Friedburg C, Bowl W, Jager M, Andrassi Darida M, et al. [Autosomal recessive bestrophinopathy (ARB): a clinical and molecular description of two patients at childhood]. Klin Monbl Augenheilkd. 2012;229:1009-17 pubmed publisher
    ..This is not only due to its low prevalence, but also to the phenotypic appearance. This paper describes typical features in two patients and discusses novel findings using improved ophthalmological diagnostic tools...
  22. Chabot S, Jabrane Ferrat N, Bigot K, Tabiasco J, Provost A, Golzio M, et al. A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor. J Exp Med. 2011;208:973-86 pubmed publisher
    ..These studies validate CD160 as a potential new target in cases of human pathological ocular and tumor neoangiogenesis that do not respond or become resistant to existing antiangiogenic drugs...
  23. Park S, Kim K, Lindsey J, Dai Y, Heo H, Nguyen D, et al. A selective inhibitor of drp1, mdivi-1, increases retinal ganglion cell survival in acute ischemic mouse retina. Invest Ophthalmol Vis Sci. 2011;52:2837-43 pubmed publisher
  24. Thapa S, Thapa R, Paudyal I, Khanal S, Aujla J, Paudyal G, et al. Prevalence and pattern of vitreo-retinal diseases in Nepal: the Bhaktapur glaucoma study. BMC Ophthalmol. 2013;13:9 pubmed publisher
    Vitreo-retinal diseases are among the leading causes of visual impairment and blindness worldwide...
  25. Mamatha G, Umashankar V, Kasinathan N, Krishnan T, Sathyabaarathi R, Karthiyayini T, et al. Molecular screening of the CYP4V2 gene in Bietti crystalline dystrophy that is associated with choroidal neovascularization. Mol Vis. 2011;17:1970-7 pubmed
    ..We report two cases of BCD associated with CNV. CYP4V2 and exon 5 of tissue inhibitor of metalloproteinase 3 (TIMP3) were screened in both cases. A patient with BCD, but without CNV, was also screened to identify pathogenic variations...
  26. Kondo M, Sanuki R, Ueno S, Nishizawa Y, Hashimoto N, Ohguro H, et al. Identification of autoantibodies against TRPM1 in patients with paraneoplastic retinopathy associated with ON bipolar cell dysfunction. PLoS ONE. 2011;6:e19911 pubmed publisher
    ..The purpose of the current study is to investigate whether there are autoantibodies against TRPM1 in the sera of PR patients exhibiting ON bipolar cell dysfunction...
  27. Le Tien V, Atmani K, Querques G, Massamba N, Souied E. Ranibizumab for subfoveal choroidal neovascularization in Bietti crystalline retinopathy. Eye (Lond). 2010;24:1728-9 pubmed publisher
  28. Wolff B, Basdekidou C, Vasseur V, Mauget Faysse M, Sahel J, Vignal C. Retinal inner nuclear layer microcystic changes in optic nerve atrophy: a novel spectral-domain OCT finding. Retina. 2013;33:2133-8 pubmed publisher
    ..Optic atrophy constitutes the final stage in the evolution of optic neuropathy. The aim of this study was to describe the presence of macular microcystic changes or pseudocysts in patients with advanced optic atrophy...
  29. Huang G, Qi X, Chui T, Zhong Z, Burns S. A clinical planning module for adaptive optics SLO imaging. Optom Vis Sci. 2012;89:593-601 pubmed publisher
  30. Girmens J, Picaud S, Sahel J. [Therapeutic innovation in AMD and other retinal diseases]. Rev Prat. 2013;63:68-73 pubmed
    ..Innovative strategies gene therapy, cell therapy, nanotechnology neuroprotection- and multidisciplinary approaches are emerging to prevent the decline in vision in aging populations and its health implications...
  31. Chan A, Saraswathy S, Rehak M, Ueki M, Rao N. Neuroglobin protection in retinal ischemia. Invest Ophthalmol Vis Sci. 2012;53:704-11 pubmed publisher
    ..To explore the role of Ngb in retinal neuroprotection during ischemia reperfusion (IR), the authors examined the effect of Ngb overexpression in the retina in vivo by using Ngb-transgenic (Ngb-Tg) mice...
  32. Gupta B, Parvizi S, Mohamed M. Bietti crystalline dystrophy and choroidal neovascularisation. Int Ophthalmol. 2011;31:59-61 pubmed publisher
    ..We present a novel finding of juxtafoveal choroidal neovascularisation in Bietti crystalline dystrophy and demonstrate a spectral domain optical coherence tomography image of this disorder...
  33. Seydel K, Fox L, Glover S, Reeves M, Pensulo P, Muiruri A, et al. Plasma concentrations of parasite histidine-rich protein 2 distinguish between retinopathy-positive and retinopathy-negative cerebral malaria in Malawian children. J Infect Dis. 2012;206:309-18 pubmed publisher
    ..Retinopathy predicts intracerebral parasite sequestration with >90% sensitivity and specificity, but detecting retinopathy requires well-trained personnel and expensive equipment...
  34. Kiernan D, Zelkha R, Hariprasad S, Lim J, Blair M, Mieler W. En face spectral-domain optical coherence tomography outer retinal analysis and relation to visual acuity. Retina. 2012;32:1077-86 pubmed publisher
    ..To describe a method of en face visualization and quantification of the photoreceptor inner segment/outer segment junction area, using spectral-domain optical coherence tomography, and association with visual acuity...
  35. Parapuram S, Cojocaru R, Chang J, Khanna R, Brooks M, Othman M, et al. Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases. PLoS ONE. 2010;5:e13885 pubmed publisher
    ..The molecular mechanisms underlying rod photoreceptor vulnerability and potential biomarkers of the aging process in this highly specialized cell type are unknown...
  36. Liu Y, Song X, Han Y, Zhou F, Zhang D, Ji B, et al. Identification of anthocyanin components of wild Chinese blueberries and amelioration of light-induced retinal damage in pigmented rabbit using whole berries. J Agric Food Chem. 2011;59:356-63 pubmed publisher
    ..2 or 4.9 g/kg/day for 4 weeks prior to light exposure effectively reduced photodamage to the retinas. This study adds to the growing body of data supporting the bioactivity of blueberries in improving mammal vision...
  37. Sjølie A, Klein R, Porta M, Orchard T, Fuller J, Parving H, et al. Retinal microaneurysm count predicts progression and regression of diabetic retinopathy. Post-hoc results from the DIRECT Programme. Diabet Med. 2011;28:345-51 pubmed publisher
    ..To study the association between baseline retinal microaneurysm score and progression and regression of diabetic retinopathy, and response to treatment with candesartan in people with diabetes...
  38. Marmor M. Comparison of screening procedures in hydroxychloroquine toxicity. Arch Ophthalmol. 2012;130:461-9 pubmed publisher
    ..To compare different screening procedures for hydroxychloroquine sulfate (Plaquenil) toxicity at different stages of damage...
  39. Hosoya K, Tomi M, Tachikawa M. Strategies for therapy of retinal diseases using systemic drug delivery: relevance of transporters at the blood-retinal barrier. Expert Opin Drug Deliv. 2011;8:1571-87 pubmed publisher
    There is an increasing need for managing rapidly progressing retinal diseases because of the potential loss of vision...
  40. Xiao X, Mai G, Li S, Guo X, Zhang Q. Identification of CYP4V2 mutation in 21 families and overview of mutation spectrum in Bietti crystalline corneoretinal dystrophy. Biochem Biophys Res Commun. 2011;409:181-6 pubmed publisher
    ..3%, and 10.3%, respectively). Our results expand the mutation spectrum of CYP4V2 and demonstrate an overview of the CYP4V2 mutation spectrum and its frequency in families with BCD. BCD is a clinically and genetically homogenous disease...
  41. Deniro M, Al Mohanna F, Al Mohanna F. Inhibition of reactive gliosis prevents neovascular growth in the mouse model of oxygen-induced retinopathy. PLoS ONE. 2011;6:e22244 pubmed publisher
    ..In addition, the study reveals that YC-1 may exert promising therapeutic effects in the treatment of retinal and neuronal pathologies...
  42. Peng P, Chao H, Juan S, Chen C, Liu J, Ko M. Pharmacological preconditioning by low dose cobalt protoporphyrin induces heme oxygenase-1 overexpression and alleviates retinal ischemia-reperfusion injury in rats. Curr Eye Res. 2011;36:238-46 pubmed publisher
    ..The aims of this study were to investigate the effects of low dose cobalt protoporphyrin IX (CoPP), an inducer of heme oxygenase-1 (HO-1), on the retina of rats against ischemia-reperfusion (IR) injury...
  43. Naycheva L, Schatz A, Rock T, Willmann G, Messias A, Bartz Schmidt K, et al. Phosphene thresholds elicited by transcorneal electrical stimulation in healthy subjects and patients with retinal diseases. Invest Ophthalmol Vis Sci. 2012;53:7440-8 pubmed publisher
    ..To evaluate electrically evoked phosphene thresholds (EPTs) in healthy subjects and in patients with retinal disease and to assess repeatability and possible correlations with common ophthalmologic tests...
  44. Awua Larbi S, Wong T, Cotch M, Durazo Arvizu R, Jacobs D, Klein B, et al. Retinal arteriolar caliber and urine albumin excretion: the Multi-Ethnic Study of Atherosclerosis. Nephrol Dial Transplant. 2011;26:3523-8 pubmed publisher
    ..Changes in retinal microvascular caliber, which occur prior to onset of retinopathy, may indicate presence of kidney damage...
  45. Tanaka J, Nakanishi T, Ogawa K, Tsuruma K, Shimazawa M, Shimoda H, et al. Purple rice extract and anthocyanidins of the constituents protect against light-induced retinal damage in vitro and in vivo. J Agric Food Chem. 2011;59:528-36 pubmed publisher
    ..These findings suggest that PRE and its anthocyanidins possess protective effects with antioxidation mechanism in both in vitro and in vivo models of retinal diseases.
  46. Rowland T, Buchholz D, Clegg D. Pluripotent human stem cells for the treatment of retinal disease. J Cell Physiol. 2012;227:457-66 pubmed publisher
    Despite advancements made in our understanding of ocular biology, therapeutic options for many debilitating retinal diseases remain limited...
  47. Meyer J, Howden S, Wallace K, Verhoeven A, Wright L, Capowski E, et al. Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment. Stem Cells. 2011;29:1206-18 pubmed publisher
    ..The production of OV-like populations from human pluripotent stem cells should facilitate the study of human retinal development and disease and advance the use of hiPSCs in personalized medicine...
  48. Chen B, Tang L. Protective effects of catalase on retinal ischemia/reperfusion injury in rats. Exp Eye Res. 2011;93:599-606 pubmed publisher
  49. Cho M, Kiss S. Detection and monitoring of sickle cell retinopathy using ultra wide-field color photography and fluorescein angiography. Retina. 2011;31:738-47 pubmed publisher
    ..In this study, we demonstrate the use of wide-field photography and fluorescein angiography to visualize the peripheral vascular changes and to identify patients with risk factors for developing proliferative sickle cell retinopathy...
  50. Krebs I, Glittenberg C, Zeiler F, Binder S. Spectral domain optical coherence tomography for higher precision in the evaluation of vitreoretinal adhesions in exudative age-related macular degeneration. Br J Ophthalmol. 2011;95:1415-8 pubmed publisher
    ..This study examines the localisation of adhesion and the direction of traction lines in eyes with exudative AMD...
  51. Stern J, Temple S. Stem cells for retinal replacement therapy. Neurotherapeutics. 2011;8:736-43 pubmed publisher
    ..Positive outcomes from these stem cell-based clinical studies would radically change the way that blinding disorders are approached in the clinic...
  52. Haddad N, Waked N, Bejjani R, Khoueir Z, Chouery E, Corbani S, et al. Clinical and molecular findings in three Lebanese families with Bietti crystalline dystrophy: report on a novel mutation. Mol Vis. 2012;18:1182-8 pubmed
    ..The aim of this study was to investigate the spectrum of mutations in CYP4V2 in Lebanese families, and to characterize the phenotype of patients affected with BCD...
  53. Klein R, Myers C, Lee K, Klein B. 15-year cumulative incidence and associated risk factors for retinopathy in nondiabetic persons. Arch Ophthalmol. 2010;128:1568-75 pubmed publisher
    ..To investigate the relationship of systemic factors to the 15-year cumulative incidence of retinopathy in nondiabetic persons in the Beaver Dam Eye Study...
  54. Gamsiz E, Ouyang Q, Schmidt M, Nagpal S, Morrow E. Genome-wide transcriptome analysis in murine neural retina using high-throughput RNA sequencing. Genomics. 2012;99:44-51 pubmed publisher
    ..Retina transcriptome studies utilizing novel sequencing methods have been highly informative and these data may also serve as a resource for the community of researchers...
  55. Audo I, Bujakowska K, Leveillard T, Mohand Said S, Lancelot M, Germain A, et al. Development and application of a next-generation-sequencing (NGS) approach to detect known and novel gene defects underlying retinal diseases. Orphanet J Rare Dis. 2012;7:8 pubmed publisher
    ..However, these methods are time consuming, expensive and unable to provide a result if the patient carries a new gene mutation. In addition, multiplicity of phenotypes associated with the same gene defect may be overlooked...
  56. Krempler K, Schmeer C, Isenmann S, Witte O, Lowel S. Simvastatin improves retinal ganglion cell survival and spatial vision after acute retinal ischemia/reperfusion in mice. Invest Ophthalmol Vis Sci. 2011;52:2606-18 pubmed publisher
  57. Chao H, Chuang M, Liu J, Liu X, Ho L, Pan W, et al. Baicalein protects against retinal ischemia by antioxidation, antiapoptosis, downregulation of HIF-1?, VEGF, and MMP-9 and upregulation of HO-1. J Ocul Pharmacol Ther. 2013;29:539-49 pubmed publisher
    ..Retinal ischemia-associated ocular disorders are vision threatening. This study examined whether the flavonoid baicalein is able to protect against retinal ischemia/reperfusion...
  58. Zobor D, Kohl S, Wissinger B, Zrenner E, Jagle H. Rod and cone function in patients with KCNV2 retinopathy. PLoS ONE. 2012;7:e46762 pubmed publisher
    ..To investigate rod and cone function and disease mechanisms in patients with KCNV2 retinopathy...
  59. Fujita T, Hirooka K, Nakamura T, Itano T, Nishiyama A, Nagai Y, et al. Neuroprotective effects of angiotensin II type 1 receptor (AT1-R) blocker via modulating AT1-R signaling and decreased extracellular glutamate levels. Invest Ophthalmol Vis Sci. 2012;53:4099-110 pubmed publisher
    ..To investigate the mechanism of the neuroprotective effects of the angiotensin II type 1 receptor (AT1-R) blocker against retinal ischemia-reperfusion injury in the rat...
  60. Azzolini C. A pilot teleconsultation network for retinal diseases in ophthalmology. J Telemed Telecare. 2011;17:20-4 pubmed publisher
    ..teleconsultation network was developed as a web application in order to provide second opinions on retinal diseases. The system provided automatic notification messages to the referring doctor and the consulted ..