degenerative myopia

Summary

Summary: Excessive axial myopia associated with complications (especially posterior staphyloma and CHOROIDAL NEOVASCULARIZATION) that can lead to BLINDNESS.

Top Publications

  1. Varano M, Parisi V, Tedeschi M, Sciamanna M, Gallinaro G, Capaldo N, et al. Macular function after PDT in myopic maculopathy: psychophysical and electrophysiological evaluation. Invest Ophthalmol Vis Sci. 2005;46:1453-62 pubmed
    ..To evaluate the effects of photodynamic therapy (PDT) on macular function in myopic subfoveal choroidal neovascularization (CNV)...
  2. Marticorena J, Gomez Ulla F, Fernandez M, Pazos B, Rodriguez Cid M, Sanchez Salorio M. Combined photodynamic therapy and intravitreal triamcinolone acetonide for the treatment of myopic subfoveal choroidal neovascularization. Am J Ophthalmol. 2006;142:335-7 pubmed
    ..To evaluate visual acuity changes and safety of combined treatment with photodynamic therapy (PDT) and intravitreal triamcinolone acetonide (IVTA) in myopic eyes with choroidal neovascularization (CNV)...
  3. Zuberbuhler B, Seyedian M, Tuft S. Phacoemulsification in eyes with extreme axial myopia. J Cataract Refract Surg. 2009;35:335-40 pubmed publisher
    ..The refractive outcome showed a hyperopic error that increased with AL, an effect that was primarily the result of the eyes that received a negative-power IOL. ..
  4. Chan W, Ohji M, Lai T, Liu D, Tano Y, Lam D. Choroidal neovascularisation in pathological myopia: an update in management. Br J Ophthalmol. 2005;89:1522-8 pubmed
    ..Future directions in the management of myopic CNV are also discussed...
  5. Yamamoto I, Rogers A, Reichel E, Yates P, Duker J. Intravitreal bevacizumab (Avastin) as treatment for subfoveal choroidal neovascularisation secondary to pathological myopia. Br J Ophthalmol. 2007;91:157-60 pubmed
    ..To evaluate the safety and efficacy of intravitreal bevacizumab (Avastin) as treatment for subfoveal choroidal neovascularisation (CNV) due to pathological myopia...
  6. Xu L, Wang Y, Li Y, Wang Y, Cui T, Li J, et al. Causes of blindness and visual impairment in urban and rural areas in Beijing: the Beijing Eye Study. Ophthalmology. 2006;113:1134.e1-11 pubmed
    ..To evaluate the causes of visual impairment and blindness in adult Chinese in an urban and rural region of Beijing, China...
  7. Shimada N, Ohno Matsui K, Baba T, Futagami S, Tokoro T, Mochizuki M. Natural course of macular retinoschisis in highly myopic eyes without macular hole or retinal detachment. Am J Ophthalmol. 2006;142:497-500 pubmed
    ..To investigate the natural course of macular retinoschisis in highly myopic patients...
  8. Zhang Q, Guo X, Xiao X, Jia X, Li S, Hejtmancik J. A new locus for autosomal dominant high myopia maps to 4q22-q27 between D4S1578 and D4S1612. Mol Vis. 2005;11:554-60 pubmed
    ..A large Chinese family with autosomal dominant high myopia was collected in order to map the genetic locus as an initial step towards identifying the genetic cause of high myopia in this family...
  9. Sayanagi K, Ikuno Y, Tano Y. Tractional internal limiting membrane detachment in highly myopic eyes. Am J Ophthalmol. 2006;142:850-2 pubmed
    ..To report the clinical features of tractional internal limiting membrane (ILM) detachment in highly myopic eyes with posterior staphyloma...

More Information

Publications99

  1. Gaucher D, Haouchine B, Tadayoni R, Massin P, Erginay A, Benhamou N, et al. Long-term follow-up of high myopic foveoschisis: natural course and surgical outcome. Am J Ophthalmol. 2007;143:455-62 pubmed
    ..To determine the natural evolution and surgical indications of myopic foveoschisis (MF), which are still poorly documented, and the factors that predict poor prognosis...
  2. Chen Y, Chen T, Yang K, Lee W, Kuo Y, Chao A, et al. Treatment of retinal detachment resulting from posterior staphyloma-associated macular hole in highly myopic eyes. Retina. 2006;26:25-31 pubmed
    ..To evaluate the surgical outcome of retinal detachment resulting from a posterior staphyloma-associated macular hole in highly myopic eyes...
  3. Alio J, Ruiz Moreno J, Shabayek M, Lugo F, Abd El Rahman A. The risk of retinal detachment in high myopia after small incision coaxial phacoemulsification. Am J Ophthalmol. 2007;144:93-98 pubmed
    ..50 Chi-square test). The incidence of RD in high myopic patients after coaxial phacoemulsification is 2.7%. A trend toward an increased incidence and risk in patients younger than 50 years of age was detected in this study. ..
  4. Kojima A, Ohno Matsui K, Futagami S, Shimada N, Tokoro T, Mochizuki M. Trans-Tenon's retrobulbar triamcinolone infusion for myopic choroidal neovascularization. Acta Ophthalmol Scand. 2006;84:749-54 pubmed
  5. Ivarsen A, Fledelius W, Hjortdal J. Three-year changes in epithelial and stromal thickness after PRK or LASIK for high myopia. Invest Ophthalmol Vis Sci. 2009;50:2061-6 pubmed publisher
    ..Stromal regrowth is most pronounced after PRK. After LASIK, regrowth is restricted to the residual stromal bed. Postoperative refractive changes correlate with changes in ST (PRK) and CT (PRK and LASIK) but not with changes in ET. ..
  6. Kim J, Park C, Chung T, Chung E. Clinical evaluation of accommodative intraocular lens implantation in high myopic eyes. Korean J Ophthalmol. 2008;22:81-6 pubmed publisher
    ..Six months clinical outcome of cataract surgery with an AT-45 for the high myopic eyes was satisfactory; it was not significantly different from that of the non-high myopic eyes. ..
  7. Konstantinidis L, Mantel I, Pournaras J, Zografos L, Ambresin A. Intravitreal ranibizumab (Lucentis) for the treatment of myopic choroidal neovascularization. Graefes Arch Clin Exp Ophthalmol. 2009;247:311-8 pubmed publisher
    ..In this small series of eyes with limited follow-up, intravitreal ranibizumab was a safe and effective treatment for CNV secondary to PM, resulting in functional and anatomic improvements. ..
  8. Lindbohm N, Tuisku I, Tervo T. LASIK for myopia of -9.00 to -17.00 D with the VISX STAR S2: 2- to 5-year follow-up. J Refract Surg. 2009;25:195-200 pubmed
    ..With careful patient selection and safety precautions, LASIK is a safe alternative with moderate stability but limited predictability in the treatment of myopia of -9.00 to -17.00 D. ..
  9. Hirakata A, Hida T. Vitrectomy for myopic posterior retinoschisis or foveal detachment. Jpn J Ophthalmol. 2006;50:53-61 pubmed
  10. Kojima A, Ohno Matsui K, Teramukai S, Ishihara Y, Shimada N, Yoshida T, et al. Estimation of visual outcome without treatment in patients with subfoveal choroidal neovascularization in pathologic myopia. Graefes Arch Clin Exp Ophthalmol. 2006;244:1474-9 pubmed
    ..We developed a linear predictive model to estimate BCVA at 5 years after onset of myopic CNV without treatment based on the identified prognostic factors. This information might be important for managing patients with myopic CNV. ..
  11. Dumas S, Glacet Bernard A, Haddad W, Razavi S, Roquet W, Coscas G, et al. [Comparison of macular limited translocation and photodynamic therapy for management of choroidal neovascularization in degenerative myopia: a retrospective study]. J Fr Ophtalmol. 2006;29:980-9 pubmed
    ..macular translocation (MT) and photodynamic therapy (PDT) in subfoveal choroidal neovascularization due to degenerative myopia, with a minimum follow-up of 12 months...
  12. Jonas J, Budde W. Optic nerve damage in highly myopic eyes with chronic open-angle glaucoma. Eur J Ophthalmol. 2005;15:41-7 pubmed
    ..To compare the amount of optic nerve damage in relation to intraocular pressure in highly myopic eyes with chronic open-angle glaucoma versus non-highly myopic eyes with chronic open-angle glaucoma...
  13. Chan W, Lai T, Chan K, Li H, Liu D, Lam D, et al. Changes in aqueous vascular endothelial growth factor and pigment epithelial-derived factor levels following intravitreal bevacizumab injections for choroidal neovascularization secondary to age-related macular degeneration or pathologic myopia. Retina. 2008;28:1308-13 pubmed publisher
    ..These changes may be favorable for the inhibition of CNV angiogenesis. ..
  14. Kojima T, Hallak J, Azar D. Control-matched analysis of laser in situ keratomileusis outcomes in high myopia. J Cataract Refract Surg. 2008;34:544-50 pubmed publisher
    ..Laser in situ keratomileusis for high myopia was safe, although the efficacy and predictability was slightly lower than for low myopia. There was no relationship between preoperative pachymetry and visual and refractive outcomes. ..
  15. Bennett M, Yee W. Pegaptanib for myopic choroidal neovascularization in a young patient. Graefes Arch Clin Exp Ophthalmol. 2007;245:903-5 pubmed
    ..Pegaptanib appears to be effective in treating myopic CNV refractive to laser photocoagulation, photodynamic therapy, and intravitreal triamcinolone acetonide. ..
  16. Kamiya K, Shimizu K, Hikita F, Komatsu M. Posterior chamber toric phakic intraocular lens implantation for high myopic astigmatism in eyes with pellucid marginal degeneration. J Cataract Refract Surg. 2010;36:164-6 pubmed publisher
    ..No author has a financial or proprietary interest in any material or method mentioned. Additional disclosures are found in the footnotes. ..
  17. Cho H, Choi A, Kang S. Effect of internal limiting membrane removal in treatment of retinal detachment caused by myopic macular hole. Korean J Ophthalmol. 2004;18:141-7 pubmed
    ..0%). In conclusion, these results suggest that the removal of the perifoveal internal limiting membrane may be an important adjuvant in the treatment of the myopic macular hole with retinal detachment. ..
  18. Kamiya K, Shimizu K, Igarashi A, Hikita F, Komatsu M. Four-year follow-up of posterior chamber phakic intraocular lens implantation for moderate to high myopia. Arch Ophthalmol. 2009;127:845-50 pubmed publisher
  19. Ohno Matsui K, Moriyama M, Hayashi K, Mochizuki M. Choroidal vein and artery occlusion following photodynamic therapy in eyes with pathologic myopia. Graefes Arch Clin Exp Ophthalmol. 2006;244:1363-6 pubmed
    ..ICG angiography at 1 week after PDT was useful to evaluate the impact of PDT on large choroidal vessels. ..
  20. Neri P, Mariotti C, Mercanti L, Salvolini S, Giovannini A. Vitritis in the contralateral uninjected eye following intravitreal bevacizumab (Avastin). Int Ophthalmol. 2008;28:425-7 pubmed
    ..No further complications were observed. Although IB has a satisfactory safety profile, the possibility of unusual complications associated with the drug or the procedure itself should always be considered. ..
  21. Wong D, Li K. Avastin in myopic choroidal neovascularisation: is age the limit?. Br J Ophthalmol. 2008;92:1011-2 pubmed publisher
  22. Li X, Wang W, Tang S, Zhao J. Gas injection versus vitrectomy with gas for treating retinal detachment owing to macular hole in high myopes. Ophthalmology. 2009;116:1182-87.e1 pubmed publisher
    ..The authors have no proprietary or commercial interest in any materials discussed in the article. ..
  23. Wang N, Wang B, Zhai G, Lei K, Wang L, Congdon N. A method of measuring anterior chamber volume using the anterior segment optical coherence tomographer and specialized software. Am J Ophthalmol. 2007;143:879-81 pubmed
    ..001) and before and after LPI in shallow AC (P < .001) and deep AC (P = .008) eyes. The ACV values obtained by this method were repeatable and in accord with clinical observation. ..
  24. Holekamp N, Thomas M, Pearson A. The safety profile of long-term, high-dose intraocular corticosteroid delivery. Am J Ophthalmol. 2005;139:421-8 pubmed
    ..To report the feasibility and safety profile of 2-mg and 6-mg fluocinolone acetonide implants after long-term follow-up in eyes with choroidal neovascularization (CNV)...
  25. Condon P, O Keefe M, Binder P. Long-term results of laser in situ keratomileusis for high myopia: risk for ectasia. J Cataract Refract Surg. 2007;33:583-90 pubmed
    ..Although high myopia has been considered a risk factor for post-LASIK ectasia, adherence to proper screening and intraoperative pachymetry appears to decrease the risk. ..
  26. Quinn G, Dobson V, Davitt B, Hardy R, Tung B, Pedroza C, et al. Progression of myopia and high myopia in the early treatment for retinopathy of prematurity study: findings to 3 years of age. Ophthalmology. 2008;115:1058-1064.e1 pubmed publisher
  27. Yu J, Wang F, Cao H, Fan Y, Zhang X. Combination of internal limiting membrane peeling and endophotocoagulation for retinal detachment related to high myopia in patients with macular hole. Ophthalmic Surg Lasers Imaging. 2010;41:215-21 pubmed publisher
  28. Mohammadpour M. Risk for ectasia with LASIK. J Cataract Refract Surg. 2008;34:181-2; author reply 182-3 pubmed publisher
  29. Chauvaud D. [A blinding orphan disease: high myopia]. Bull Acad Natl Med. 2005;189:867-72; discussion 872 pubmed
    ..Certain mechanisms of this visual handicap have been elucidated by the use of new imaging technologies, raising new therapeutic possibilities. ..
  30. Ratiglia R, Osnaghi S, Bindella A, Pirondini C. Posterior traction retinal detachment in highly myopic eyes: clinical features and surgical outcome as evaluated by optical coherence tomography. Retina. 2005;25:473-8 pubmed
    ..A posteriorly detached retina can be reattached surgically, but visual improvement may be limited by the presence of other chorioretinal myopic lesions and persistent cystoid macular changes. ..
  31. Martinez Castillo V, Boixadera A, Verdugo A, Elies D, Coret A, Garcia Arumi J. Rhegmatogenous retinal detachment in phakic eyes after posterior chamber phakic intraocular lens implantation for severe myopia. Ophthalmology. 2005;112:580-5 pubmed
    ..The characteristics of RRD do not differ from the natural history of retinal detachment. Surgical management of RRD was successful in restoring vision in our patients. This article contains additional online-only material available at . ..
  32. Ikuno Y, Gomi F, Tano Y. Potent retinal arteriolar traction as a possible cause of myopic foveoschisis. Am J Ophthalmol. 2005;139:462-7 pubmed
    ..This finding suggests that the inward tractional force on the retina along the arteriole may be closely related to the pathogenesis of vitreoretinal diseases specific to high myopia, including MF or paravascular microhole formation. ..
  33. Chan W, Lai T, Liu D, Lam D. Intravitreal bevacizumab (Avastin) for myopic choroidal neovascularisation: 1-year results of a prospective pilot study. Br J Ophthalmol. 2009;93:150-4 pubmed publisher
    ..010). The 1-year outcomes confirmed the results of previous short-term studies that intravitreal bevacizumab is effective for myopic CNV, with a high proportion of patients sustaining visual gain after treatment. ..
  34. Neuhann I, Neuhann T, Heimann H, Schmickler S, Gerl R, Foerster M. Retinal detachment after phacoemulsification in high myopia: analysis of 2356 cases. J Cataract Refract Surg. 2008;34:1644-57 pubmed publisher
    ..The risk profile for postoperative RD in this series cannot be distinguished from the risk profile for idiopathic RD in myopia of this extent. The true effect of prophylactic treatment of degenerative lesions remains to be elucidated. ..
  35. Yoon J, Byun Y, Koh H. Intravitreal anti-VEGF versus photodynamic therapy with verteporfin for treatment of myopic choroidal neovascularization. Retina. 2010;30:418-24 pubmed publisher
    ..7% in the PDT group (P = 0.02) and 21.4% in the combination group (P = 0.07). Intravitreal anti-VEGF injection is superior to PDT alone or a combination of PDT with anti-VEGF for treating myopic choroidal neovascularization. ..
  36. Nguyen Q, Shah S, Hafiz G, Do D, Haller J, Pili R, et al. Intravenous bevacizumab causes regression of choroidal neovascularization secondary to diseases other than age-related macular degeneration. Am J Ophthalmol. 2008;145:257-266 pubmed
    ..It may be worthwhile to consider further evaluation of systemic bevacizumab in young patients with CNV. ..
  37. Ozdek S, Hondur A, Gurelik G, Hasanreisoglu B. Transpupillary thermotherapy for myopic choroidal neovascularization: 1-year follow-up: TTT for myopic CNV. Int Ophthalmol. 2005;26:127-33 pubmed
    ..TTT seems to stabilize myopic CNVs both clinically and as revealed by angiography, with a significant decrease in the activity of lesions. Longer term results are required to evaluate the stabilizing effect of TTT in myopic CNV. ..
  38. Arias L, Planas N, Prades S, Caminal J, Rubio M, Pujol O, et al. Intravitreal bevacizumab (Avastin) for choroidal neovascularisation secondary to pathological myopia: 6-month results. Br J Ophthalmol. 2008;92:1035-9 pubmed publisher
    ..To determine the efficacy and safety of intravitreal Avastin (bevacizumab) in the treatment of choroidal neovascularisation (CNV) secondary to pathological myopia (PM)...
  39. Panozzo G, Mercanti A. Vitrectomy for myopic traction maculopathy. Arch Ophthalmol. 2007;125:767-72 pubmed
    ..To describe the results of vitrectomy in highly myopic eyes affected by a form of posterior vitreous traction termed myopic traction maculopathy (MTM)...
  40. Ruiz Moreno J, Gomez Ulla F, Montero J, Ares S, Lopez Lopez F, Rodriguez M, et al. Intravitreous bevacizumab to treat subfoveal choroidal neovascularization in highly myopic eyes: short-term results. Eye (Lond). 2009;23:334-8 pubmed
    ..To describe the anatomical and visual outcome of subfoveal and juxtafoveal choroidal neovascularization (CNV) in highly myopic eyes treated by intravitreal bevacizumab...
  41. Au Eong K. Initial experience of macular translocation in Singapore - one-year results. Ann Acad Med Singapore. 2004;33:641-8 pubmed
    ..This paper reports the 1-year results of the first 2 cases of macular translocation in Singapore...
  42. Garcia Layana A, Salinas Alaman A, Maldonado M, Sainz Gómez C, Fernández Hortelano A. Optical coherence tomography to monitor photodynamic therapy in pathological myopia. Br J Ophthalmol. 2006;90:555-8 pubmed
    ..To evaluate the role of optical coherence tomography (OCT) in determining choroidal neovascularisation (CNV) activity before and after photodynamic therapy (PDT) in patients with pathological myopia...
  43. Kubicka Trzaska A, Romanowska Dixon B. Non-malignant uveitis masquerade syndromes. Klin Oczna. 2008;110:203-6 pubmed
  44. Komeima K, Kikuchi M, Ito Y, Terasaki H, Miyake Y. Paravascular inner retinal cleavage in a highly myopic eye. Arch Ophthalmol. 2005;123:1449-50 pubmed
  45. Cai J, Cheng J, Ma X, Li Y, Li Y, Wei R. Krypton yellow laser for the treatment of macular hole in high myopia without retinal detachment. Clin Invest Med. 2008;31:E357-61 pubmed
    ..To evaluate the prophylactic effect of krypton yellow laser for the treatment of macular holes in high myopic eyes in order to reduce the risk of retinal detachment...
  46. Ikuno Y, Jo Y, Hamasaki T, Tano Y. Ocular risk factors for choroidal neovascularization in pathologic myopia. Invest Ophthalmol Vis Sci. 2010;51:3721-5 pubmed publisher
    ..posterior staphyloma height 3 mm from the fovea, length of retinal pigment epithelium (RPE) curvature within 6 mm measured on SD-OCT images, and choroidal degeneration and lacquer crack formation, graded according to a published..
  47. de Benito Llopis L, Teus M, Sánchez Pina J. Comparison between LASEK with mitomycin C and LASIK for the correction of myopia of -7.00 to -13.75 D. J Refract Surg. 2008;24:516-23 pubmed
    ..To compare laser epithelial keratomileusis (LASEK) and LASIK for the correction of high myopia...
  48. Mehdizadeh M, Nowroozzadeh M. Dome-shaped macula in eyes with myopic posterior staphyloma. Am J Ophthalmol. 2008;146:478; author reply 478-9 pubmed publisher
  49. Smiddy W, Kim S, Lujan B, Gregori G. Myopic traction maculopathy: spectral domain optical coherence tomographic imaging and a hypothesized mechanism. Ophthalmic Surg Lasers Imaging. 2009;40:169-73 pubmed
    ..SD-OCT imaging allowed better resolution of macular features but requires evaluation of all scan data. The source of progressive inner retinal traction may be the posterior extension of the staphyloma...
  50. Milani P, Pierro L, Scialdone A. OCT-guided photodynamic therapy for angiographic occult CNV in pathologic myopia. Eur J Ophthalmol. 2008;18:837-40 pubmed
    ..The authors report on the successfully OCT-guided photodynamic therapy (PDT) of an angiographic occult CNV complicating PM...
  51. Georgalas I, Ezra E. Delayed closure after surgery for a full-thickness macular hole in a highly myopic eye. Can J Ophthalmol. 2007;42:341-2 pubmed
  52. Chen Z, Wang I, Shih Y, Lin L. The association of haplotype at the lumican gene with high myopia susceptibility in Taiwanese patients. Ophthalmology. 2009;116:1920-7 pubmed publisher
    ..To investigate the association of genetic polymorphisms in the dermatan sulfate proteoglycan 3 (DSPG3), lumican (LUM), and decorin (DCN) genes (component genes of the sclera) with high myopia susceptibility in Taiwanese people...
  53. Montero J, Ruiz Moreno J. Treatment of choroidal neovascularization in high myopia. Curr Drug Targets. 2010;11:630-44 pubmed
    ..The aim of this review is to summarize the recent advances in myopic CNV pathophysiology and the new therapeutic targets and drugs that are changing the clinical management of myopic CNV. ..
  54. Fledelius H, Goldschmidt E. Optic disc appearance and retinal temporal vessel arcade geometry in high myopia, as based on follow-up data over 38 years. Acta Ophthalmol. 2010;88:514-20 pubmed publisher
    ..To discuss (i) optic disc appearance and (ii) the retinal course of the temporal vessel arcade in a longitudinal series of high myopia patients followed between the ages of 16 and 54...
  55. Mehdizadeh M, Ashraf H. Prevalence of cataract type in relation to axial length in subjects with high myopia and emmetropia in an Indian population. Am J Ophthalmol. 2008;146:329-30; author reply 330-1 pubmed publisher
  56. Gaucher D, Erginay A, Lecleire Collet A, Haouchine B, Puech M, Cohen S, et al. Dome-shaped macula in eyes with myopic posterior staphyloma. Am J Ophthalmol. 2008;145:909-14 pubmed publisher
    ..To describe an unusual feature in myopic eyes responsible for visual loss, which we call a dome-shaped macula...
  57. Mandal S, Venkatesh P, Sampangi R, Garg S. Intravitreal bevacizumab (Avastin) as primary treatment for myopic choroidal neovascularization. Eur J Ophthalmol. 2007;17:620-6 pubmed
    ..To evaluate the short-term efficacy and safety of intravitreal bevacizumab in myopic choroidal neovascularization (mCNV)...
  58. Ripandelli G, Coppè A, Parisi V, Stirpe M. Fellow eye findings of highly myopic subjects operated for retinal detachment associated with a macular hole. Ophthalmology. 2008;115:1489-93 pubmed publisher
    ..To identity anatomic risk factors involved in the onset of retinal complications causing decrease of visual acuity (VA) in the fellow eyes of highly myopic patients operated for retinal detachment with macular hole (RDMH)...
  59. Chan W, Lai T, Wong A, Liu D, Lam D. Combined photodynamic therapy and intravitreal triamcinolone injection for the treatment of choroidal neovascularisation secondary to pathological myopia: a pilot study. Br J Ophthalmol. 2007;91:174-9 pubmed
    ..To assess the efficacy and safety of combined intravitreal triamcinolone (IVTA) and photodynamic therapy (PDT) with verteporfin in the treatment of choroidal neovascularisation (CNV) secondary to pathological myopia...
  60. Fujiwara T, Imamura Y, Margolis R, Slakter J, Spaide R. Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes. Am J Ophthalmol. 2009;148:445-50 pubmed publisher
    ..To measure macular choroidal thickness (CT) in highly myopic eyes using enhanced depth imaging optical coherence tomography (OCT)...
  61. Shimada N, Ohno Matsui K, Yoshida T, Futagami S, Tokoro T, Mochizuki M. Development of macular hole and macular retinoschisis in eyes with myopic choroidal neovascularization. Am J Ophthalmol. 2008;145:155-161 pubmed
    ..To determine whether the chorioretinal atrophy (ChRA) adjacent to a choroidal neovascularization (CNV) is related to the development of a macular hole or macular retinoschisis in highly myopic eyes...
  62. Wakabayashi T, Ikuno Y, Gomi F, Hamasaki T, Tano Y. Intravitreal bevacizumab vs sub-tenon triamcinolone acetonide for choroidal neovascularization attributable to pathologic myopia. Am J Ophthalmol. 2009;148:591-596.e1 pubmed publisher
    ..To compare the visual outcomes of intravitreal bevacizumab (Avastin; Genentech Inc, South San Franciso, California, USA) and sub-Tenon triamcinolone acetonide (TA) for choroidal neovascularization attributable to pathologic myopia (mCNV)...
  63. Soubrane G. Choroidal neovascularization in pathologic myopia: recent developments in diagnosis and treatment. Surv Ophthalmol. 2008;53:121-38 pubmed publisher
    ..The evidence for the beneficial effects of laser photocoagulation, photodynamic therapy with verteporfin, surgery, and other techniques in the treatment of choroidal neovascularization secondary to pathologic myopia will be evaluated...
  64. Yodoi Y, Tsujikawa A, Nakanishi H, Otani A, Tamura H, Ojima Y, et al. Central retinal sensitivity after intravitreal injection of bevacizumab for myopic choroidal neovascularization. Am J Ophthalmol. 2009;147:816-24, 824.e1 pubmed publisher
    ..To evaluate retinal sensitivity in the macular area after intravitreal injection of bevacizumab in eyes with myopic choroidal neovascularization (mCNV)...
  65. Han W, Leung K, Fung W, Mak J, Li Y, Yap M, et al. Association of PAX6 polymorphisms with high myopia in Han Chinese nuclear families. Invest Ophthalmol Vis Sci. 2009;50:47-56 pubmed publisher
    ..The paired box 6 (PAX6) gene is critical to eye development. Based on prior linkage evidence, this study was conducted to investigate the association of PAX6 polymorphisms with high myopia in a Han Chinese population...
  66. Ieong A, Rubin G, Allan B. Quality of life in high myopia: implantable Collamer lens implantation versus contact lens wear. Ophthalmology. 2009;116:275-80 pubmed publisher
    ..To compare vision-related quality of life in implantable Collamer lens (ICL) recipients and successful contact lens (CL) wearers not seeking refractive surgery...
  67. Shimada N, Ohno Matsui K, Yoshida T, Yasuzumi K, Kojima A, Kobayashi K, et al. Characteristics of peripapillary detachment in pathologic myopia. Arch Ophthalmol. 2006;124:46-52 pubmed
    ..To evaluate the prevalence and clinical features of a newly recognized peripapillary lesion specific to high myopia, peripapillary detachment in pathologic myopia (PDPM), in a large series of patients with high myopia...
  68. Wu P, Chen Y, Chen C, Chen Y, Kao M, Shin S, et al. Subthreshold transpupillary thermotherapy in Chinese patients with myopic choroidal neovascularization: one- and two-year follow up. Clin Exp Ophthalmol. 2008;36:443-8 pubmed
    ..To perform a safety and efficacy study of subthreshold transpupillary thermotherapy (TTT) in Chinese patients with choroidal neovascularization (CNV) secondary to pathologic myopia...
  69. Laud K, Spaide R, Freund K, Slakter J, Klancnik J. Treatment of choroidal neovascularization in pathologic myopia with intravitreal bevacizumab. Retina. 2006;26:960-3 pubmed
  70. Sayanagi K, Ikuno Y, Soga K, Wakabayashi T, Tano Y. Marginal crack after intravitreal bevacizumab for myopic choroidal neovascularization. Acta Ophthalmol. 2009;87:460-3 pubmed publisher
    ..To report new indocyanine green angiographic (ICGA) findings after intravitreal bevacizumab (IVB) for myopic choroidal neovascularization (mCNV)...
  71. Taban M, Memoracion Peralta D, Wang H, Al Gazali L, Traboulsi E. Cohen syndrome: report of nine cases and review of the literature, with emphasis on ophthalmic features. J AAPOS. 2007;11:431-7 pubmed
    ..To review the clinical features of reported cases of Cohen syndrome with a focus on ophthalmic features and report nine new cases...
  72. Scholda C, Wirtitsch M, Biowski R, Stur M. Primary silicone oil tamponade without retinopexy in highly myopic eyes with central macular hole detachments. Retina. 2005;25:141-6 pubmed
  73. Cohen S. Anti-VEGF drugs as the 2009 first-line therapy for choroidal neovascularization in pathologic myopia. Retina. 2009;29:1062-6 pubmed publisher
    ..This review summarizes the data supplied by published case series studies about anti-VEGF therapy in mCNV...
  74. Silva R, Ruiz Moreno J, Rosa P, Carneiro A, Nascimento J, Rito L, et al. Intravitreal ranibizumab for myopic choroidal neovascularization: 12-month results. Retina. 2010;30:407-12 pubmed publisher
    ..The purpose of this study was to evaluate the safety and efficacy of intravitreal ranibizumab after 12 months in the treatment of choroidal neovascularization secondary to pathologic myopia...
  75. Theodossiadis G, Theodossiadis P. The macular buckling procedure in the treatment of retinal detachment in highly myopic eyes with macular hole and posterior staphyloma: mean follow-up of 15 years. Retina. 2005;25:285-9 pubmed
    ..To evaluate the long-term anatomical and functional results of the macular buckling procedure in myopic macular hole with retinal detachment and posterior staphyloma...
  76. Tewari A, Dhalla M, Apte R. Intravitreal bevacizumab for treatment of choroidal neovascularization in pathologic myopia. Retina. 2006;26:1093-4 pubmed
  77. Yan Z, Wang C, Chen W, Song X. Biomechanical considerations: evaluating scleral reinforcement materials for pathological myopia. Can J Ophthalmol. 2010;45:252-5 pubmed publisher
    ..We tested the biomechanical properties of 3 types of scleral reinforcement materials (artificial pericardium, human sclera, and all-dermal matrix) in an attempt to select the ideal material for the reinforcement of pathologic sclera...
  78. Forte R, Manzi G, Gallo O, de Crecchio G. Three-dimensional visualization of vitreoretinal abnormalities in high myopia. Ophthalmic Surg Lasers Imaging. 2009;40:304-7 pubmed
    ..The 3D imaging of vitreomacular tractions could help physicians plan the appropriate surgical approach in patients with myopic posterior detachment due to macular hole...
  79. Nguyen Q, Shah S, Tatlipinar S, Do D, Anden E, Campochiaro P. Bevacizumab suppresses choroidal neovascularisation caused by pathological myopia. Br J Ophthalmol. 2005;89:1368-70 pubmed
  80. Sakaguchi H, Ikuno Y, Gomi F, Kamei M, Sawa M, Tsujikawa M, et al. Intravitreal injection of bevacizumab for choroidal neovascularisation associated with pathological myopia. Br J Ophthalmol. 2007;91:161-5 pubmed
    ..To assess the efficacy and safety of an intravitreal injection of bevacizumab (Avastin(R)) for myopic choroidal neovascularisation (mCNV)...
  81. Cheng S, Yang C, Lee C, Yang C, Huang J, Ho T, et al. Anatomical and functional outcome of surgery of primary rhegmatogenous retinal detachment in high myopic eyes. Eye (Lond). 2008;22:70-6 pubmed
    ..To analyse the anatomical and functional outcome of surgery for primary rhegmatogenous retinal detachment (RRD) in highly myopic eyes...
  82. Kamiya K, Shimizu K, Igarashi A, Komatsu M. Comparison of Collamer toric implantable [corrected] contact lens implantation and wavefront-guided laser in situ keratomileusis for high myopic astigmatism. J Cataract Refract Surg. 2008;34:1687-93 pubmed publisher
    ..To compare the postoperative visual outcomes after implantation of a Collamer toric implantable contact lens (ICL) and after wavefront-guided laser in situ keratomileusis in high myopic astigmatism...
  83. Lofoco G, Ciucci F, Bardocci A, Quercioli P, De Gaetano C, Ghirelli G, et al. Efficacy of topical plus intracameral anesthesia for cataract surgery in high myopia: randomized controlled trial. J Cataract Refract Surg. 2008;34:1664-8 pubmed publisher
    ..To assess the efficacy of intracameral lidocaine supplementation of topical anesthesia during cataract surgery in eyes with high myopia...
  84. Shimada N, Ohno Matsui K, Yoshida T, Sugamoto Y, Tokoro T, Mochizuki M. Progression from macular retinoschisis to retinal detachment in highly myopic eyes is associated with outer lamellar hole formation. Br J Ophthalmol. 2008;92:762-4 pubmed publisher
    ..To investigate the morphological changes that occur during the development of an early retinal detachment (RD) from a myopic macular retinoschisis (MRS) by optical coherence tomography (OCT)...
  85. Ikuno Y, Sayanagi K, Soga K, Sawa M, Tsujikawa M, Gomi F, et al. Intravitreal bevacizumab for choroidal neovascularization attributable to pathological myopia: one-year results. Am J Ophthalmol. 2009;147:94-100.e1 pubmed publisher
    ..To assess the potential effect of intravitreal bevacizumab (IVB) (Avastin) on retinal function and anatomic recovery in eyes with choroidal neovascularization attributable to pathological myopia (mCNV)...
  86. Fernández Robredo P, Maestre S, Zarranz Ventura J, Mulero H, Salinas Alaman A, Garcia Layana A. Myopic choroidal neovascularization genetics. Ophthalmology. 2008;115:1632, 1632.e1 pubmed publisher
  87. Pece A, Vadalà M, Manzi R, Calori G. Back pain after photodynamic therapy with verteporfin. Am J Ophthalmol. 2006;141:593-4 pubmed
    ..To report the incidence of back pain after photodynamic therapy, which suggests methods for prevention that are related to its pathogenesis...
  88. Yamaguchi T, Negishi K, Kato N, Arai H, Toda I, Tsubota K. Factors affecting contrast sensitivity with the Artisan phakic intraocular lens for high myopia. J Refract Surg. 2009;25:25-32 pubmed
    ..To evaluate the factors affecting postoperative visual function in eyes with Artisan phakic intraocular lenses (PIOLs)...
  89. Wang N, Chen Y, Lai C, Chen T, Yang K, Kuo Y, et al. Paediatric retinal detachment: comparison of high myopia and extreme myopia. Br J Ophthalmol. 2009;93:650-5 pubmed publisher
    ..To compare the clinical features and surgical outcomes of paediatric retinal detachment (RD) in high myopia and extreme myopia...
  90. Satofuka S, Imamura Y, Ishida S, Ozawa Y, Tsubota K, Inoue M. Rhegmatogenous retinal detachment associated with primary congenital glaucoma. Int Ophthalmol. 2008;28:369-71 pubmed
    ..We present the characteristics and surgical outcomes of three cases with a RRD who had CG and had undergone surgery many years earlier...