angle closure glaucoma

Summary

Summary: A form of glaucoma in which the intraocular pressure increases because the angle of the anterior chamber is blocked and the aqueous humor cannot drain from the anterior chamber.

Top Publications

  1. Sihota R, Saxena R, Agarwal H. Entropion uveae: early sphincter atrophy, signposting primary angle closure glaucoma?. Eur J Ophthalmol. 2004;14:290-7 pubmed
    An easily recognized clinical marker for early changes of primary angle closure glaucoma (PACG) or eyes predisposed to angle closure is important so that timely laser iridotomy can prevent morbidity...
  2. Lee G, Tam C, Danesh Meyer H, Myers J, Katz L. Bilateral angle closure glaucoma induced by sulphonamide-derived medications. Clin Exp Ophthalmol. 2007;35:55-8 pubmed
    ..We report the occurrence of bilateral angle closure glaucoma with sulphonamide-derived medications and highlight features of the presentation and treatment to assist ..
  3. Desai C, Ramchandani S, Bhopale S, Ramchandani S. Acute myopia and angle closure caused by topiramate, a drug used for prophylaxis of migraine. Indian J Ophthalmol. 2006;54:195-7 pubmed
    ..We report a case of acute progressive myopia and bilateral angle closure due to Topiramate--a drug used for epilepsy and migraine prophylaxis...
  4. Lee J, Kim Y, Jung H. Distribution and characteristics of peripheral anterior synechiae in primary angle-closure glaucoma. Korean J Ophthalmol. 2006;20:104-8 pubmed
    ..To evaluate the characteristics of peripheral anterior synechiae (PAS) in primary angle-closure glaucoma (PACG)...
  5. Cong Y, Guo X, Liu X, Cao D, Jia X, Xiao X, et al. Association of the single nucleotide polymorphisms in the extracellular matrix metalloprotease-9 gene with PACG in southern China. Mol Vis. 2009;15:1412-7 pubmed
    To study the association of the single nucleotide polymorphisms (SNPs) rs17576 and rs2250889 in the extracellular matrix metalloprotease-9 (MMP-9) gene with primary angle closure glaucoma (PACG) in southern Chinese patients.
  6. Seo J, Park K, Kim Y, Yoo Y, Kang S, Kim D. Differences in the histopathology and matrix metalloproteinase expression in Tenon's tissue of primary open-angle glaucoma and primary angle-closure glaucoma. Korean J Ophthalmol. 2008;22:37-42 pubmed publisher
  7. Hauben M, Reich L. Reports of acute angle closure glaucoma-related adverse events with SSRIs: results of a disproportionality analysis. CNS Drugs. 2006;20:327-9 pubmed
  8. Lee J, Lee J, Lee K. Prognostic factors for the success of laser iridotomy for acute primary angle closure glaucoma. Korean J Ophthalmol. 2009;23:286-90 pubmed publisher
    ..To identify the prognostic factors for successful laser iridotomy for acute angle-closure glaucoma (AACG)...
  9. How A, Kumar R, Chen Y, Su D, Gao H, Oen F, et al. A randomised crossover study comparing bimatoprost and latanoprost in subjects with primary angle closure glaucoma. Br J Ophthalmol. 2009;93:782-6 pubmed publisher
    To compare the intraocular pressure (IOP) lowering efficacy and side effects of latanoprost 0.005% and bimatoprost 0.03% in subjects with chronic primary angle closure glaucoma (PACG).

More Information

Publications67

  1. Thomas R, Sekhar G, Parikh R. Primary angle closure glaucoma: a developing world perspective. Clin Exp Ophthalmol. 2007;35:374-8 pubmed
    Primary angle closure glaucoma (PACG) is estimated to affect a significant proportion of the population worldwide. Of those affected, the majority reside in developing countries...
  2. Friedman D, Vedula S. Lens extraction for chronic angle-closure glaucoma. Cochrane Database Syst Rev. 2006;:CD005555 pubmed
    ..This can result from an anterior placement of the lens due to an increase in the thickness of the lens (as occurs with aging), anterior displacement by a posterior force (for example choroidal effusion), or laxity of the zonules...
  3. Tham C, Kwong Y, Leung D, Lam S, Li F, Chiu T, et al. Phacoemulsification versus combined phacotrabeculectomy in medically uncontrolled chronic angle closure glaucoma with cataracts. Ophthalmology. 2009;116:725-31, 731.e1-3 pubmed publisher
    To compare phacoemulsification alone versus combined phacotrabeculectomy in medically uncontrolled chronic angle closure glaucoma (CACG) with coexisting cataract.
  4. Euswas A, Warrasak S. Intraocular pressure control following phacoemulsification in patients with chronic angle closure glaucoma. J Med Assoc Thai. 2005;88 Suppl 9:S121-5 pubmed
    ..IOP) and glaucoma control following phacoemulsification with posterior chamber intraocular lens implantation in patients who had chronic angle closure glaucoma (CACG) whose peripheral anterior synechiae (PAS) were less than 270 degrees.
  5. Boonyaleephan S. Bilateral acute onset myopia and angle closure glaucoma after oral topiramate: a case report. J Med Assoc Thai. 2008;91:1904-7 pubmed
    ..Describe bilateral acute onset myopia and angle-closure glaucoma as ocular adverse effects of topiramate...
  6. He M, Lu Y, Liu X, Ye T, Foster P. Histologic changes of the iris in the development of angle closure in Chinese eyes. J Glaucoma. 2008;17:386-92 pubmed publisher
    ..To identify the histologic characteristics of the iris in primary angle closure...
  7. Aung T, Yong V, Lim M, Venkataraman D, Toh J, Chew P, et al. Lack of association between the rs2664538 polymorphism in the MMP-9 gene and primary angle closure glaucoma in Singaporean subjects. J Glaucoma. 2008;17:257-8 pubmed publisher
    ..the single nucleotide polymorphism (SNP) rs2664538 within the MMP-9 gene with risk for acute primary angle closure glaucoma (PACG)...
  8. Fang A, Qu J, Li L, Ji B. Measurement of retinal nerve fiber layer in primary acute angle closure glaucoma by optical coherence tomography. J Glaucoma. 2007;16:178-84 pubmed
    To detect the objective structure changes of the retinal nerve fiber layer (RNFL) in primary acute angle closure glaucoma (PAACG) and to evaluate the efficacy of quantitative assessment of RNFL thickness with optical coherence tomography (..
  9. Yip J, Foster P. Ethnic differences in primary angle-closure glaucoma. Curr Opin Ophthalmol. 2006;17:175-80 pubmed
    ..Therefore it is important to review these studies in the light of a consistent classification system...
  10. Lachkar Y, Bouassida W. Drug-induced acute angle closure glaucoma. Curr Opin Ophthalmol. 2007;18:129-33 pubmed
    Acute angle closure glaucoma is a potentially blinding side effect of a number of local and systemic drugs, including adrenergic, both anticholinergic and cholinergic, antidepressant and antianxiety, sulfa-based, and anticoagulant agents...
  11. Kumar R, Tantisevi V, Wong M, Laohapojanart K, Chansanti O, Quek D, et al. Plateau iris in Asian subjects with primary angle closure glaucoma. Arch Ophthalmol. 2009;127:1269-72 pubmed publisher
    To determine the prevalence of plateau iris in Asian eyes with primary angle closure glaucoma (PACG) using ultrasound biomicroscopy (UBM).
  12. Keenan T, Salmon J, Yeates D, Goldacre M. Trends in rates of primary angle closure glaucoma and cataract surgery in England from 1968 to 2004. J Glaucoma. 2009;18:201-5 pubmed publisher
    ..The aim of this study was to examine trends over time in rates of primary angle closure glaucoma (PACG) in England, and to compare these rates with rates of cataract surgery.
  13. Sihota R, Saxena R, Taneja N, Venkatesh P, Sinha A. Topography and fluorescein angiography of the optic nerve head in primary open-angle and chronic primary angle closure glaucoma. Optom Vis Sci. 2006;83:520-6 pubmed
    ..of this study is to correlate optic nerve head topography with fluorescein angiography of the optic nerve head in patients with primary open-angle glaucoma (POAG), chronic primary angle closure glaucoma (CPACG), and normal controls.
  14. Kaushik S, Sachdev N, Pandav S, Gupta A, Ram J. Bilateral acute angle closure glaucoma as a presentation of isolated microspherophakia in an adult: case report. BMC Ophthalmol. 2006;6:29 pubmed
    Bilateral simultaneous angle closure glaucoma is a rare entity. To our knowledge this is the first reported case of bilateral acute angle-closure glaucoma secondary to isolated microspherophakia in an adult.
  15. Brandão M, Fernandes I, Barradas F, Machado J, Oliveira M. [Acute myopia and angle closure glaucoma associated with topiramate use in a young patient: case report]. Arq Bras Oftalmol. 2009;72:103-5 pubmed
    ..We make a link with similar cases described in medical journals and in a bibliographic review related to this entity...
  16. Shukla S, Damji K, Harasymowycz P, Chialant D, Kent J, Chevrier R, et al. Clinical features distinguishing angle closure from pseudoplateau versus plateau iris. Br J Ophthalmol. 2008;92:340-4 pubmed publisher
  17. Chen H, Huang M, Tsai Y, Hung P, Lin E. Comparing glaucomatous optic neuropathy in primary open angle and primary angle closure glaucoma eyes by scanning laser polarimetry-variable corneal compensation. J Glaucoma. 2008;17:105-10 pubmed publisher
    ..fiber layer thickness difference between high-tension primary open angle glaucoma (HT-POAG) and primary angle closure glaucoma (PACG) eyes using scanning laser polarimetry-variable corneal compensation (GDx VCC) in Taiwan-Chinese ..
  18. Aung T, Lim M, Wong T, Thalamuthu A, Yong V, Venkataraman D, et al. Molecular analysis of CHX10 and MFRP in Chinese subjects with primary angle closure glaucoma and short axial length eyes. Mol Vis. 2008;14:1313-8 pubmed
    The genetic basis of primary angle closure glaucoma (PACG) has yet to be elucidated...
  19. Vijaya L, George R, Arvind H, Baskaran M, Ve Ramesh S, Raju P, et al. Prevalence of primary angle-closure disease in an urban south Indian population and comparison with a rural population. The Chennai Glaucoma Study. Ophthalmology. 2008;115:655-660.e1 pubmed
    ..To determine the prevalence of primary angle-closure glaucoma (PACG), primary angle closure (PAC), and PAC suspect (PACS) in an urban population, and to compare prevalence and associated risk factors with a rural population...
  20. Dai X, Nie S, Ke T, Liu J, Wang Q, Liu M. [Two variants in MYOC and CYP1B1 genes in a Chinese family with primary angle-closure glaucoma]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2008;25:493-6 pubmed
    ..To describe the clinical and genetic characteristics of a Chinese family with primary angle-closure glaucoma (PACG)...
  21. Tu Y, Yin Z, Pen H, Yuan C. Genetic heritability of a shallow anterior chamber in Chinese families with primary angle closure glaucoma. Ophthalmic Genet. 2008;29:171-6 pubmed publisher
    To explore the genetic heritability of a shallow anterior chamber (AC) in families with primary angle closure glaucoma (PACG) and to provide a theoretical basis for the identification of candidate genes responsible for PACG.
  22. Sihota R, Ghate D, Mohan S, Gupta V, Pandey R, Dada T. Study of biometric parameters in family members of primary angle closure glaucoma patients. Eye (Lond). 2008;22:521-7 pubmed
    To measure ocular biometric parameters in all possible untreated family members of index primary angle closure glaucoma (PACG) patients and to correlate these values among affected, unaffected, and suspected family members.
  23. Ahmed M. Management of intermittent angle closure glaucoma with Nd: YAG laser iridotomy as a primary procedure. J Coll Physicians Surg Pak. 2006;16:764-7 pubmed
    To assess the efficacy and complications of Nd: YAG laser iridotomy in patients with intermittent (sub-acute) angle closure glaucoma.
  24. Wang I, Chiang T, Shih Y, Lu S, Lin L, Shieh J, et al. The association of single nucleotide polymorphisms in the MMP-9 genes with susceptibility to acute primary angle closure glaucoma in Taiwanese patients. Mol Vis. 2006;12:1223-32 pubmed
    ..the relationships between single nucleotide polymorphisms (SNPs) of extracellular matrix, matrix metalloproteases (MMPs), tissue inhibitors of MMPs, and other glaucoma-associated genes and acute primary angle closure glaucoma (PACG).
  25. Zelefsky J, Fine H, Rubinstein V, Hsu I, Finger P. Escitalopram-induced uveal effusions and bilateral angle closure glaucoma. Am J Ophthalmol. 2006;141:1144-7 pubmed
    To report the onset of bilateral angle closure glaucoma resulting from ciliochoroidal effusions noted after taking escitalopram.
  26. Vijaya L, George R, Arvind H, Baskaran M, Paul P, Ramesh S, et al. Prevalence of angle-closure disease in a rural southern Indian population. Arch Ophthalmol. 2006;124:403-9 pubmed
    ..To estimate the prevalence of primary angle-closure glaucoma, primary angle closure (PAC), and primary angle-closure suspect (PACS) and its associated risk factors in a rural population in southern India...
  27. Cao D, Liu X, Guo X, Cong Y, Huang J, Mao Z. Investigation of the association between CALCRL polymorphisms and primary angle closure glaucoma. Mol Vis. 2009;15:2202-8 pubmed
    To determine whether the polymorphisms of calcitonin receptor-like receptor gene (CALCRL) are associated with primary angle closure glaucoma (PACG) in a southern Chinese population.
  28. Tham C, Leung D, Kwong Y, Li F, Lai J, Lam D. Effects of phacoemulsification versus combined phaco-trabeculectomy on drainage angle status in primary angle closure glaucoma (PACG). J Glaucoma. 2010;19:119-23 pubmed publisher
    To document anatomic effects of phacoemulsification versus combined phaco-trabeculectomy on drainage angle in primary angle closure glaucoma (PACG).
  29. Vishwakarma P, Raman G, Sathyan P. Mefenamic acid-induced bilateral transient myopia, secondary angle closure glaucoma and choroidal detachment. Indian J Ophthalmol. 2009;57:398-400 pubmed publisher
    ..We describe here a patient who presented with secondary angle closure glaucoma and myopia following mefenamic acid ingestion which was managed successfully by stopping the medication, ..
  30. Tenkir A, Bekele S, Solomon B. Weill Marchesani syndrome with chronic angle closure glaucoma in Ethiopia: a case report. Ethiop Med J. 2009;47:81-3 pubmed
    ..of WMS in an 18-year old female Ethiopian patient who presented with progressive visual loss from chronic angle closure glaucoma secondary to lens subluxation...
  31. Stangler F, Prietsch R, Fortes Filho J. [Bilateral acute angle closure glaucoma in a young patient receiving oral topiramate: case report]. Arq Bras Oftalmol. 2007;70:133-6 pubmed
    This paper reports a clinical case of uveal effusion in both eyes causing bilateral acute angle closure glaucoma in a young patient after oral administration of topiramate, a new anticonvulsant medication...
  32. Chua J, Seet L, Jiang Y, Su R, Htoon H, Charlton A, et al. Increased SPARC expression in primary angle closure glaucoma iris. Mol Vis. 2008;14:1886-92 pubmed
    ..SPARC (secreted protein, acidic, and rich in cysteine) is involved in extracellular matrix (ECM) organization. The purpose of this study was to evaluate the expression of SPARC in iris tissue from primary angle closure glaucoma (PACG) eyes.
  33. Kumar R, Quek D, Lee K, Oen F, Sakai H, Koh V, et al. Confirmation of the presence of uveal effusion in Asian eyes with primary angle closure glaucoma: an ultrasound biomicroscopy study. Arch Ophthalmol. 2008;126:1647-51 pubmed publisher
    To confirm the presence of uveal effusion in the eyes of Asian patients with primary angle closure glaucoma (PACG) using ultrasound biomicroscopy (UBM).
  34. Tham C, Kwong Y, Leung D, Lam S, Li F, Chiu T, et al. Phacoemulsification versus combined phacotrabeculectomy in medically controlled chronic angle closure glaucoma with cataract. Ophthalmology. 2008;115:2167-2173.e2 pubmed publisher
    To compare phacoemulsification alone versus combined phacotrabeculectomy in medically controlled chronic angle closure glaucoma (CACG) with coexisting cataract.
  35. Wang I, Lin S, Chiang T, Chen Z, Lin L, Hung P, et al. The association of membrane frizzled-related protein (MFRP) gene with acute angle-closure glaucoma--a pilot study. Mol Vis. 2008;14:1673-9 pubmed
    ..The purpose of our study was to investigate whether there are significant associations between angle-closure glaucoma and sequence variants in the MFRP gene reported previously in Taiwanese subjects...
  36. Michael S, Qamar R, Akhtar F, Khan W, Ahmed A. C677T polymorphism in the methylenetetrahydrofolate reductase gene is associated with primary closed angle glaucoma. Mol Vis. 2008;14:661-5 pubmed
    ..To determine whether or not there is an association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with disease in cohorts of primary open-angle glaucoma (POAG) and primary closed-angle glaucoma (PCAG) from Pakistan...
  37. Sachi D, Vijaya L. Topiramate induced secondary angle closure glaucoma. J Postgrad Med. 2006;52:72-3 pubmed
  38. Sihota R, Mohan S, Dada T, Gupta V, Pandey R, Ghate D. An evaluation of the darkroom prone provocative test in family members of primary angle closure glaucoma patients. Eye (Lond). 2007;21:984-9 pubmed
    To compare ocular biometric parameters with darkroom prone provocative test (DRPPT) in family members of primary angle closure glaucoma (PACG) patients.
  39. Zorić Geber M, Mandic Z, Korsić J, Novak Laus K. [Combined laser treatment in the management of acute and subacute primary angle closure glaucoma]. Acta Med Croatica. 2006;60:117-20 pubmed
    Primary angle closure glaucoma remains a disease with high visual morbidity worldwide...
  40. Ittner L, Schwerdtfeger K, Kunz T, Muff R, Husmann K, Grimm C, et al. Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma. Clin Sci (Lond). 2008;114:49-58 pubmed
    ..The CLR transgenic mice used in the present study provide a model for acute angle-closure glaucoma...
  41. Bhattacharjee H, Bhattacharjee K, Medhi J, DasGupta S. Clear lens extraction and intraocular lens implantation in a case of microspherophakia with secondary angle closure glaucoma. Indian J Ophthalmol. 2010;58:67-70 pubmed publisher
    ..acrylic foldable intraocular lens (IOL) in a 19-year-old boy with microspherophakia, high myopia and angle closure glaucoma is described...
  42. Lachkar Y. [Acute angle closure and angle closure glaucoma: Phacoemulsification as first-line treatment]. J Fr Ophtalmol. 2010;33:273-8 pubmed publisher
    b>Angle closure glaucoma is characterized by an optic neuropathy with a glaucomatous visual field defect with a white painless eye and mimics primary open-angle glaucoma...
  43. Amerasinghe N, Aung T. Angle-closure: risk factors, diagnosis and treatment. Prog Brain Res. 2008;173:31-45 pubmed publisher
    ..Pupil-block, anterior nonpupil-block (plateau iris and peripheral iris crowding), lens related and retrolenticular mechanisms have been suggested as the four main mechanisms of angle closure...
  44. Lavanya R, Wong T, Friedman D, Aung H, Alfred T, Gao H, et al. Determinants of angle closure in older Singaporeans. Arch Ophthalmol. 2008;126:686-91 pubmed publisher
    ..To investigate systemic and ocular risk factors for angle closure (AC) in older Singaporeans and to determine if these risk factors are different in men vs women and in Chinese vs non-Chinese persons...
  45. Hu C, Lin H, Chen C. A 7-year population study of primary angle closure glaucoma admissions and climate in Taiwan. Ophthalmic Epidemiol. 2008;15:66-72 pubmed publisher
    ..hospital admissions in Taiwan, this study sets out to investigate meteorological factors associated with primary angle closure glaucoma (PACG). We investigated the relationship between PACG admissions and five different climate indices.
  46. Abu Amero K, Morales J, Osman M, Bosley T. Nuclear and mitochondrial analysis of patients with primary angle-closure glaucoma. Invest Ophthalmol Vis Sci. 2007;48:5591-6 pubmed
    ..In this study, patients with primary angle-closure glaucoma (PACG) were examined for mutations in nuclear genes reported to be associated with glaucoma and for possible mitochondrial abnormalities...
  47. Shakya S, Gupta H. Angle closure glaucoma: a cause for bilateral visual threat. Nepal Med Coll J. 2006;8:153-5 pubmed
    Glaucoma is one of the leading causes of blindness worldwide. Primary angle closure glaucoma (PACG) is a leading cause ofblindness in East Asian people and known to cause bilateral blindness more frequently than other glaucoma...
  48. He M, Foster P, Ge J, Huang W, Zheng Y, Friedman D, et al. Prevalence and clinical characteristics of glaucoma in adult Chinese: a population-based study in Liwan District, Guangzhou. Invest Ophthalmol Vis Sci. 2006;47:2782-8 pubmed
    ..To assess the prevalence and mechanism of glaucoma in adults living in an urban area of southern China...
  49. Park S, Heo H, Yang K. Comparison of ultrasound biomicroscopic changes after glaucoma triple procedure and trabeculectomy in eyes with primary angle closure glaucoma. J Glaucoma. 2009;18:311-5 pubmed publisher
    To evaluate ultrasound biomicroscopy changes in the anterior chamber angle (ACA) configuration after glaucoma triple procedure (GTP), compared with those seen after trabeculectomy, in eyes with primary angle closure glaucoma (PACG).
  50. Lin J, Fosnot J, Edmond J. Bilateral angle closure glaucoma in a child receiving oral topiramate. J AAPOS. 2003;7:66-8 pubmed
  51. Lai J, Lee V, Leung D, Chung T. Decompression retinopathy following laser peripheral iridoplasty for acute primary angle-closure. Eye (Lond). 2005;19:1345-7 pubmed
  52. Liu C, Huang Y, Ju J, Lu C, Chiu A. Altered transcripts expression of matrix metalloproteinases and their tissue inhibitors in tenon capsule of patients with glaucoma. J Glaucoma. 2004;13:486-91 pubmed
    ..001), and TIMP-2 (P < 0.001) (Mann-Whitney U tests). The transcripts expression of certain MMPs and TIMPs is altered in Tenon capsule of glaucoma patients, which might result from long-term application of topical glaucoma medications. ..
  53. Hayashi K, Hayashi H, Nakao F, Hayashi F. Effect of cataract surgery on intraocular pressure control in glaucoma patients. J Cataract Refract Surg. 2001;27:1779-86 pubmed
    ..0055). Cataract surgery substantially reduced IOP and the number of medications required for IOP control in glaucomatous eyes. Specifically, cataract extraction normalized the IOP in most eyes with ACG. ..
  54. Choi J, Kim Y. Progression of peripheral anterior synechiae after laser iridotomy. Am J Ophthalmol. 2005;140:1125-7 pubmed
    ..To determine the incidence and to characterize the risk factors of peripheral anterior synechiae (PAS) progression after laser iridotomy (LI)...
  55. Raychaudhuri A, Lahiri S, Bandyopadhyay M, Foster P, Reeves B, Johnson G. A population based survey of the prevalence and types of glaucoma in rural West Bengal: the West Bengal Glaucoma Study. Br J Ophthalmol. 2005;89:1559-64 pubmed
    ..To determine (i) the prevalence of glaucoma in people aged > or =50 years, (ii) the proportions of different types of glaucoma, (iii) the distributions of intraocular pressure and vertical cup disc ratio...
  56. Fraunfelder F, Fraunfelder F, Keates E. Topiramate-associated acute, bilateral, secondary angle-closure glaucoma. Ophthalmology. 2004;111:109-11 pubmed
    ..To evaluate spontaneous reports of ocular side effects associated with topiramate use...
  57. Craig J, Ong T, Louis D, Wells J. Mechanism of topiramate-induced acute-onset myopia and angle closure glaucoma. Am J Ophthalmol. 2004;137:193-5 pubmed
    ..Interventional case report...
  58. Ge J, Guo Y, Liu Y, Lin M, Zhuo Y, Chen B, et al. New management of angle-closure glaucoma by phacoemulsification with foldable posterior chamber intraocular lens implantation. Yan Ke Xue Bao. 2000;16:22-8 pubmed
    ..To investigate the management of angle-closure glaucoma by phacoemulsification with foldable posterior chamber intraocular lens (PC-IOL) implantation...