conjunctivitis

Summary

Summary: INFLAMMATION of the CONJUNCTIVA.

Top Publications

  1. Rodríguez Ares M, Abdulkader I, Blanco A, Touriño Peralba R, Ruiz Ponte C, Vega A, et al. Ligneous conjunctivitis: a clinicopathological, immunohistochemical, and genetic study including the treatment of two sisters with multiorgan involvement. Virchows Arch. 2007;451:815-21 pubmed
    Ligneous conjunctivitis (LC) is a rare disease characterized by wood-like pseudomembranes developing on the ocular and extraocular mucosae secondary to plasminogen (PLG) deficiency...
  2. Schuster V, Hugle B, Tefs K. Plasminogen deficiency. J Thromb Haemost. 2007;5:2315-22 pubmed
    ..Ligneous conjunctivitis is by far the most common clinical manifestation...
  3. Menon B, Govindarajan B. Identification of an atypical zinc metalloproteinase, ZmpC, from an epidemic conjunctivitis-causing strain of Streptococcus pneumoniae. Microb Pathog. 2013;56:40-6 pubmed publisher
    ..In this regard, we recently reported a mechanism used by a nonencapsulated, epidemic conjunctivitis-causing strain of S. pneumoniae (strain SP168) to gain access into ocular surface epithelial cells...
  4. Nguyen E, Azar D, Papalkar D, McCluskey P. Brimonidine-induced anterior uveitis and conjunctivitis: clinical and histologic features. J Glaucoma. 2008;17:40-2 pubmed publisher
    ..We report a case of bilateral anterior uveitis and granulomatous papillary conjunctivitis in a 78-year-old gentleman after 2 years of brimonidine therapy...
  5. Sorbara L, Jones L, Williams Lyn D. Contact lens induced papillary conjunctivitis with silicone hydrogel lenses. Cont Lens Anterior Eye. 2009;32:93-6 pubmed publisher
    To describe the refitting of a soft lens wearer into a silicone hydrogel lens due to neovascularization. This change, in turn, caused contact lens induced papillary conjunctivitis (CLPC) and a further refitting was necessary.
  6. Zegans M, Sanchez P, Likosky D, Allar R, Martin M, Schwartzman J, et al. Clinical features, outcomes, and costs of a conjunctivitis outbreak caused by the ST448 strain of Streptococcus pneumoniae. Cornea. 2009;28:503-9 pubmed publisher
    An outbreak of pneumococcal conjunctivitis occurred at Dartmouth College in 2002. We describe the clinical features, outcomes, and costs associated with this outbreak.
  7. Liyanage S, Wearne M. Lacrimal canaliculitis as a cause of recurrent conjunctivitis. Optometry. 2009;80:479-80 pubmed publisher
    Bacterial conjunctivitis is routinely managed by optometrists. This case report describes a case of lacrimal canaliculitis, which is a cause for nonresolving conjunctivitis and is commonly misdiagnosed.
  8. Azad N, Zafar S, Khan A. Successful treatment of ligneous conjunctivitis with topical cyclosporine and heparin. J AAPOS. 2009;13:519-20 pubmed publisher
    Ligneous conjunctivitis is a rare disease characterized by wood-like pseudomembranes developing on the ocular and extraocular mucosae...
  9. Kari O, Haahtela T, Laine P, Turunen J, Kari M, Sarna S, et al. Cellular characteristics of non-allergic eosinophilic conjunctivitis. Acta Ophthalmol. 2010;88:245-50 pubmed publisher
    This study examines the histology of conjunctival biopsy samples from patients with persistent allergic eosinophilic conjunctivitis (AEC) or non-allergic eosinophilic conjunctivitis (NAEC).

More Information

Publications65

  1. Marimon J, Ercibengoa M, Garcia Arenzana J, Alonso M, Perez Trallero E. Streptococcus pneumoniae ocular infections, prominent role of unencapsulated isolates in conjunctivitis. Clin Microbiol Infect. 2013;19:E298-305 pubmed publisher
    ..isolates causing ocular infections in a region of northern Spain in two periods: 1999-2010 for episodes of conjunctivitis (n = 612) and 1980-2010 for uncommon and more severe non-conjunctival ocular infections (n = 36)...
  2. Bjorksten B, Clayton T, Ellwood P, Stewart A, Strachan D. Worldwide time trends for symptoms of rhinitis and conjunctivitis: Phase III of the International Study of Asthma and Allergies in Childhood. Pediatr Allergy Immunol. 2008;19:110-24 pubmed
    ..The increases were more pronounced in the older age group, suggesting that environmental influences on the development of allergy may not be limited to early childhood...
  3. Wada T, Kida T, Inoue T, Tokushige H, Naka H, Sakaki H. Immunomodulatory effect of gatifloxacin on mouse peritoneal macrophages in vitro and in models of endotoxin-induced rat conjunctivitis and rabbit bacterial keratitis. Ophthalmic Res. 2008;40:54-60 pubmed publisher
    ..To determine the anti-inflammatory activity of gatifloxacin in ophthalmic use...
  4. Mendes M, Moraes M, Renoiner E, Dantas M, Lanzieri T, Fonseca C, et al. Acute conjunctivitis with episcleritis and anterior uveitis linked to adiaspiromycosis and freshwater sponges, Amazon region, Brazil, 2005. Emerg Infect Dis. 2009;15:633-9 pubmed publisher
    ..Symptomatic children responded to corticosteroid treatment. Adiaspiromycosis is a preventable cause of ocular disease in the Amazon region...
  5. Betanzos Cabrera G, Juárez Verdayes M, González González G, Cancino Diaz M, Cancino Diaz J. Gatifloxacin, moxifloxacin, and balofloxacin resistance due to mutations in the gyrA and parC genes of Staphylococcus epidermidis strains isolated from patients with endophthalmitis, corneal ulcers and conjunctivitis. Ophthalmic Res. 2009;42:43-8 pubmed publisher
    ..Our aim was to address the quinolone resistance and to explore the resistance mechanism in S. epidermidis strains isolated from ocular infections...
  6. Smith A, Waycaster C. Estimate of the direct and indirect annual cost of bacterial conjunctivitis in the United States. BMC Ophthalmol. 2009;9:13 pubmed publisher
    The aim of this study was to estimate both the direct and indirect annual costs of treating bacterial conjunctivitis (BC) in the United States. This was a cost of illness study performed from a U.S. healthcare payer perspective.
  7. Kakar S, Bhalla P, Maria A, Rana M, Chawla R, Mathur N. Chlamydia trachomatis causing neonatal conjunctivitis in a tertiary care center. Indian J Med Microbiol. 2010;28:45-7 pubmed publisher
    Chlamydia trachomatis is considered a major aetiological agent of conjunctivitis in newborns...
  8. Brewer J, Ekdawi N, Torgerson R, Camilleri M, Bruce A, Rogers R, et al. Lichen planus and cicatricial conjunctivitis: disease course and response to therapy of 11 patients. J Eur Acad Dermatol Venereol. 2011;25:100-4 pubmed publisher
    ..Lichen planus is an autoimmune, inflammatory dermatosis of unknown cause that affects the skin and mucous membranes...
  9. Cavone L, Muzzi M, Mencucci R, Sparatore B, Pedrazzi M, Moroni F, et al. 18?-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis. Ocul Immunol Inflamm. 2011;19:180-5 pubmed publisher
    ..Evidence indicates that extracellularly released high-mobility group box 1 protein (HMGB1) behaves as a cytokine, promoting inflammation and disease pathogenesis. HMGB1 release occurs during endophtalmitis or uveoretinitis...
  10. Fernández Robredo P, Recalde S, Moreno Orduña M, García García L, Zarranz Ventura J, Garcia Layana A. Azithromycin reduces inflammation in a rat model of acute conjunctivitis. Mol Vis. 2013;19:153-65 pubmed
    ..The effect of azithromycin on inflammatory molecules in the lipopolysaccharide-induced rat conjunctivitis model was investigated.
  11. Belser J, Davis C, Balish A, Edwards L, Zeng H, Maines T, et al. Pathogenesis, transmissibility, and ocular tropism of a highly pathogenic avian influenza A (H7N3) virus associated with human conjunctivitis. J Virol. 2013;87:5746-54 pubmed publisher
    ..findings indicate that the recently isolated North American lineage H7 subtype virus associated with human conjunctivitis is capable of causing severe disease in mice and spreading to naive-contact ferrets, while concurrently ..
  12. Origlieri C, Bielory L. Emerging drugs for conjunctivitis. Expert Opin Emerg Drugs. 2009;14:523-36 pubmed publisher
    b>Conjunctivitis is a highly prevalent ocular condition with potential complications that include visual impairment...
  13. Williams G, Saw V, Saeed T, Evans S, Cottrell P, Curnow S, et al. Validation of a fornix depth measurer: a putative tool for the assessment of progressive cicatrising conjunctivitis. Br J Ophthalmol. 2011;95:842-7 pubmed publisher
    Documentation of conjunctival forniceal foreshortening in cases of progressive cicatrising conjunctivitis (PCC) is important in ascertaining disease stage and progression...
  14. Pandey A, Madan M, Asthana A, Das A, Kumar S, Jain K. External ophthalmomyiasis caused by Oestrus ovis: a rare case report from India. Korean J Parasitol. 2009;47:57-9 pubmed publisher
    ..A 25-year-old farmer presented with severe symptoms of conjunctivitis. The larvae, 3 in number, were observed in the bulbar conjunctiva, and following removal the symptoms of eye ..
  15. Murugan K, Usha M, Malathi P, Al Sohaibani A, Chandrasekaran M. Biofilm forming multi drug resistant Staphylococcus spp. among patients with conjunctivitis. Pol J Microbiol. 2010;59:233-9 pubmed
    ..They were isolated from ocular patients suffering from conjunctivitis. In this study we analyzed biofilm forming ability, antibiotic resistance profile of the Staphylococcus spp...
  16. Barabino S, Rolando M. Amniotic membrane transplantation in a case of ligneous conjunctivitis. Am J Ophthalmol. 2004;137:752-3 pubmed
    To report a case of ligneous conjunctivitis treated with amniotic membrane transplantation. Interventional case report...
  17. Everitt H, Little P. How do GPs diagnose and manage acute infective conjunctivitis? A GP survey. Fam Pract. 2002;19:658-60 pubmed
    To determine GPs' diagnosis and management of acute infective conjunctivitis (AIC)-one of the commonest but least researched acute infections seen in primary care...
  18. Schott D, Dempfle C, Beck P, Liermann A, Mohr Pennert A, Goldner M, et al. Therapy with a purified plasminogen concentrate in an infant with ligneous conjunctivitis and homozygous plasminogen deficiency. N Engl J Med. 1998;339:1679-86 pubmed
  19. Barabino S, Rolando M, Bentivoglio G, Mingari C, Zanardi S, Bellomo R, et al. Role of amniotic membrane transplantation for conjunctival reconstruction in ocular-cicatricial pemphigoid. Ophthalmology. 2003;110:474-80 pubmed
    ..To evaluate the role and the effectiveness over time of amniotic membrane transplantation (AMT) as a first-step procedure to treat conjunctival reconstruction in late-stage ocular-cicatricial pemphigoid (OCP)...
  20. Drew A, Kaufman A, Kombrinck K, Danton M, Daugherty C, Degen J, et al. Ligneous conjunctivitis in plasminogen-deficient mice. Blood. 1998;91:1616-24 pubmed
    Ligneous conjunctivitis is a rare form of chronic pseudomembranous conjunctivitis that is associated with systemic membranous pathological changes...
  21. Schrauder A, Altmann D, Laude G, Claus H, Wegner K, Kohler R, et al. Epidemic conjunctivitis in Germany, 2004. Euro Surveill. 2006;11:185-7 pubmed
    Epidemic conjunctivitis can be associated with viral or bacterial pathogens, whereas epidemic keratoconjunctivitis is caused mainly by adenoviruses type 8,19 and 37...
  22. Zamir E, Mechoulam H, Micera A, Levi Schaffer F, Pe er J. Inflamed juvenile conjunctival naevus: clinicopathological characterisation. Br J Ophthalmol. 2002;86:28-30 pubmed
    ..Their clinical and histopathological features have not been characterised in series of patients. The aim of the study is to characterise IJCN clinically and histopathologically...
  23. Thorne J, Jabs D, Nikolskaia O, Mimouni D, Anhalt G, Nousari H. Lichen planus and cicatrizing conjunctivitis: characterization of five cases. Am J Ophthalmol. 2003;136:239-43 pubmed
    To report the clinical and immunopathologic features and the response to therapy in a series of six patients with cicatrizing conjunctivitis due to lichen planus.
  24. Carvalho M, Steigerwalt A, Thompson T, Jackson D, Facklam R. Confirmation of nontypeable Streptococcus pneumoniae-like organisms isolated from outbreaks of epidemic conjunctivitis as Streptococcus pneumoniae. J Clin Microbiol. 2003;41:4415-7 pubmed
    Eleven isolates representing five distinct outbreaks of pneumococcal conjunctivitis were examined for phenotypic and genetic characteristics...
  25. Cai Y, Fukushi H, Koyasu S, Kuroda E, Yamaguchi T, Hirai K. An etiological investigation of domestic cats with conjunctivitis and upper respiratory tract disease in Japan. J Vet Med Sci. 2002;64:215-9 pubmed
    ..1%), 11 (16.7%) and 14 (21.2%) cats respectively, from 66 domestic cats presented with conjunctivitis and upper respiratory tract disease (URTD) in 9 prefectures of Japan...
  26. Heidemann D, Williams G, Hartzer M, Ohanian A, Citron M. Treatment of ligneous conjunctivitis with topical plasmin and topical plasminogen. Cornea. 2003;22:760-2 pubmed
    To describe treatment of a child with recalcitrant ligneous conjunctivitis secondary to a systemic plasminogen deficiency.
  27. Thorne J, Anhalt G, Jabs D. Mucous membrane pemphigoid and pseudopemphigoid. Ophthalmology. 2004;111:45-52 pubmed
    ..To describe the clinical characteristics of patients with mucous membrane pemphigoid (MMP) and pseudopemphigoid...
  28. Robinson M, Lee S, Rubin B, Wayne A, Pavletic S, Bishop M, et al. Topical corticosteroid therapy for cicatricial conjunctivitis associated with chronic graft-versus-host disease. Bone Marrow Transplant. 2004;33:1031-5 pubmed
    ..was performed on seven patients treated with topical ocular corticosteroid therapy for progressive cicatricial conjunctivitis associated with chronic graft-versus-host disease (GVHD) following hematopoietic stem cell transplantation...
  29. Grammer L, Ditto A, Tripathi A, Harris K. Prevalence and onset of rhinitis and conjunctivitis in subjects with occupational asthma caused by trimellitic anhydride (TMA). J Occup Environ Med. 2002;44:1179-81 pubmed
    Individuals with occupational asthma may also report symptoms of rhinitis or conjunctivitis. The objective of this study was to investigate the prevalence of rhinitis and conjunctivitis in subjects with occupational asthma as a result of ..
  30. Durnian J, Olujohungbe A, Kyle G. Bilateral acute uveitis and conjunctivitis after zoledronic acid therapy. Eye (Lond). 2005;19:221-2 pubmed
  31. Park A, Webster G, Penne R, Raber I. Porphyria cutanea tarda presenting as cicatricial conjunctivitis. Am J Ophthalmol. 2002;134:619-21 pubmed
    To report a case of porphyria cutanea tarda presenting as cicatricial conjunctivitis.
  32. Pryor J, Martin M, Whitney C, Turco J, Baumgartner Y, Zegans M. Rapid response to a conjunctivitis outbreak: the use of technology to leverage information. J Am Coll Health. 2002;50:267-71 pubmed
    When an outbreak of conjunctivitis was identified at a rural New England college early in 2002, the college health center medical staff used various information management and communication systems to alert the community to the situation...
  33. Finger C. Brazil faces worst outbreak of conjunctivitis in 20 years. Lancet. 2003;361:1714 pubmed
  34. Schuster V, Seregard S. Ligneous conjunctivitis. Surv Ophthalmol. 2003;48:369-88 pubmed
    Ligneous conjunctivitis (McKusick 217090) is a rare form of chronic conjunctivitis characterized by the development of firm fibrin-rich, woody-like pseudomembraneous lesions mainly on the tarsal conjunctivae...
  35. Skolnick C, Doughman D. Erosive conjunctivitis and punctal stenosis secondary to docetaxel (taxotere). Eye Contact Lens. 2003;29:134-5 pubmed
    To report a case of erosive conjunctivitis and punctal stenosis occurring secondarily in a patient who underwent administration of docetaxel.
  36. Gautrin D, Ghezzo H, Infante Rivard C, Malo J. Incidence and host determinants of work-related rhinoconjunctivitis in apprentice pastry-makers. Allergy. 2002;57:913-8 pubmed
    ..The aim of this work was to determine the incidence of work-related rhinoconjunctivitis (RC) symptoms and their determinants...
  37. Kitaichi N, Ariga T, Ohno S, Shimizu T. Acute unilateral conjunctivitis after rubella vaccination: the detection of the rubella genome in the inflamed conjunctiva by reverse transcriptase-polymerase-chain reaction. Br J Ophthalmol. 2006;90:1436-7 pubmed
  38. Oka T, Shearer T, Azuma M. Involvement of cyclooxygenase-2 in rat models of conjunctivitis. Curr Eye Res. 2004;29:27-34 pubmed
    ..Using two animal models to determine which isoform of cyclooxygenase (COX), constitutive COX-1 or inducible COX-2, is involved in the progression of anterior ocular inflammation...
  39. Cakmak S, Dales R, Burnett R, Judek S, Coates F, Brook J. Effect of airborne allergens on emergency visits by children for conjunctivitis and rhinitis. Lancet. 2002;359:947-8 pubmed
    The effect of fungal spores and pollen grains on morbidity from childhood conjunctivitis and rhinitis is mostly unknown...
  40. Barabasi Z. [Treatment of conjunctivitis]. Orv Hetil. 2004;145:2107-10 pubmed
  41. Aoki K, Kawana R, Matsumoto I, Maekawa H, Sawada H, Sakurada N, et al. An epidemic of acute hemorrhagic conjunctivitis in the city of Sao Paulo. Jpn J Ophthalmol. 1987;31:532-7 pubmed
    This is a clinical and laboratory report on 98 patients with acute viral conjunctivitis who were referred to the Eye Clinic of the Escola Paulista de Medicina of Sao Paulo, Brazil, from February 1983 to February 1984...
  42. Watts P, Suresh P, Mezer E, Ells A, Albisetti M, Bajzar L, et al. Effective treatment of ligneous conjunctivitis with topical plasminogen. Am J Ophthalmol. 2002;133:451-5 pubmed
    The etiology of ligneous conjunctivitis is now known to be due to an underlying type 1 plasminogen deficiency. We hereby report the clinical features of three cases and their response to topically administered plasminogen.
  43. Sharma P, Singh G. A review of plant species used to treat conjunctivitis. Phytother Res. 2002;16:1-22 pubmed
    b>Conjunctivitis is a major occular external infection in tropical countries. Although not a very serious disease, it gives much discomfort and sometimes leads to partial blindness or blindness due to corneal involvement...
  44. Faraj H, Hoang Xuan T. Chronic cicatrizing conjunctivitis. Curr Opin Ophthalmol. 2001;12:250-7 pubmed
    ..Other well-known causes include thermal and chemical burns, postinfectious conjunctivitis, and Stevens-Johnson syndrome...
  45. Rampazzo A, Appino S, Pregel P, Tarducci A, Zini E, Biolatti B. Prevalence of Chlamydophila felis and feline herpesvirus 1 in cats with conjunctivitis in northern Italy. J Vet Intern Med. 2003;17:799-807 pubmed
    The prevalence of Chlamydophila felis and feline herpesvirus 1 (FHV-1) infection in cats with conjunctivitis in northern Italy was investigated by conventional polymerase chain reaction (PCR) testing...
  46. Tabbara K. Prevention of ligneous conjunctivitis by topical and subconjunctival fresh frozen plasma. Am J Ophthalmol. 2004;138:299-300 pubmed
    To present a case of ligneous conjunctivitis where the recurrence of membranous conjunctivitis was prevented by subconjunctival and topical instillation of fresh frozen plasma.
  47. Ariga T, Shimada Y, Ohgami K, Tagawa Y, Ishiko H, Aoki K, et al. New genome type of adenovirus serotype 4 caused nosocomial infections associated with epidemic conjunctivitis in Japan. J Clin Microbiol. 2004;42:3644-8 pubmed
    Human adenovirus type 4 is one of the major serotypes isolated from patients with adenoviral conjunctivitis. In 2001 we encountered nosocomial infections with epidemic conjunctivitis in the ophthalmology ward of one hospital in Sapporo, ..
  48. Messmer E, Mackert M, Zapp D, Kampik A. In vivo confocal microscopy of normal conjunctiva and conjunctivitis. Cornea. 2006;25:781-8 pubmed
    ..To analyze the appearance of normal conjunctiva and conjunctival inflammation by in vivo confocal microscopy...
  49. Porat N, Greenberg D, Givon Lavi N, Shuval D, Trefler R, Segev O, et al. The important role of nontypable Streptococcus pneumoniae international clones in acute conjunctivitis. J Infect Dis. 2006;194:689-96 pubmed
    ..nontypable Streptococcus pneumoniae isolates were found to be highly associated with sporadic cases of acute conjunctivitis (AC)...
  50. Tefs K, Gueorguieva M, Klammt J, Allen C, Aktas D, Anlar F, et al. Molecular and clinical spectrum of type I plasminogen deficiency: A series of 50 patients. Blood. 2006;108:3021-6 pubmed
    ..The most common clinical manifestations among these patients were ligneous conjunctivitis (80%) and ligneous gingivitis (34%), followed by less common manifestations such as ligneous vaginitis (8%), ..
  51. Nguyen Van Tam J, Nair P, Acheson P, Baker A, Barker M, Bracebridge S, et al. Outbreak of low pathogenicity H7N3 avian influenza in UK, including associated case of human conjunctivitis. Euro Surveill. 2006;11:E060504.2 pubmed
  52. Fathy F, El Barghathi A, El Ahwal A, El Bagar S. Study on human ophthalmomyiasis externa caused by Oestrus ovis larva, in Sirte-Libya: parasite features, clinical presentation and management. J Egypt Soc Parasitol. 2006;36:265-82, following 282 pubmed
    ..Misdiagnosis is common and the condition of acute catarrhal conjunctivitis is ascribed to other causes. The study included 20 patients referred to university hospital of Sirte, Libya...
  53. Zinchuk O, Fukushima A, Zinchuk V, Fukata K, Ueno H. Direct action of platelet activating factor (PAF) induces eosinophil accumulation and enhances expression of PAF receptors in conjunctivitis. Mol Vis. 2005;11:114-23 pubmed
    ..and PAF receptor (PAF-R) in the recruitment of eosinophils into the conjunctiva in the course of PAF induced conjunctivitis. Eosinophils are important players in the immediate hypersensitivity reactions and in allergic conjunctivitis...
  54. Ellwood P, Asher M, Beasley R, Clayton T, Stewart A. The international study of asthma and allergies in childhood (ISAAC): phase three rationale and methods. Int J Tuberc Lung Dis. 2005;9:10-6 pubmed
  55. Bingen E, Cohen R, Jourenkova N, Gehanno P. Epidemiologic study of conjunctivitis-otitis syndrome. Pediatr Infect Dis J. 2005;24:731-2 pubmed
    We conducted a prospective cross-sectional epidemiologic study of conjunctivitis-otitis syndrome during two 3-week periods of consecutive winters...
  56. Al Wazzan K, Almas K, Al Qahtani M, Al Shethri S, Khan N. Prevalence of ocular injuries, conjunctivitis and use of eye protection among dental personnel in Riyadh, Saudi Arabia. Int Dent J. 2001;51:89-94 pubmed
    ..To find out the prevalence of ocular injury and infection among dental personnel in Riyadh, Saudi Arabia...