sargassum

Summary

Summary: One of the largest genera of BROWN ALGAE, comprised of more than 150 species found in tropical, subtropical, and temperate zones of both hemispheres. Some species are attached (benthic) but most float in the open sea (pelagic). Sargassum provides a critical habitat for hundreds of species of FISHES; TURTLES; and INVERTEBRATES.

Top Publications

  1. Balaji Raghavendran H, Sathivel A, Devaki T. Antioxidant effect of Sargassum polycystum (Phaeophyceae) against acetaminophen induced changes in hepatic mitochondrial enzymes during toxic hepatitis. Chemosphere. 2005;61:276-81 pubmed
    The present study was aimed to examine the protective effects of Sargassum polycystum (Phaeophyceae) alcoholic extract on changes in liver mitochondrial enzymes against acetaminophen induced toxic hepatitis in experimental rats...
  2. Lodeiro P, Herrero R, de Vicente M. The use of protonated Sargassum muticum as biosorbent for cadmium removal in a fixed-bed column. J Hazard Mater. 2006;137:244-53 pubmed
    The protonated Sargassum muticum seaweed was studied as a possible biosorbent for cadmium removal in a fixed-bed column. The experiments were conducted in order to determine the effect of flow rate (0...
  3. Dias P, Siqueira J, Maraschin M, Ferreira A, Gagliardi A, Ribeiro do Valle R. A polysaccharide isolated from the brown seaweed Sargassum stenophyllum exerts antivasculogenic effects evidenced by modified morphogenesis. Microvasc Res. 2008;75:34-44 pubmed
    A polysaccharide (Sarg) extracted from the brown marine alga Sargassum stenophyllum was studied for its antivasculogenic effects in both in vivo and in vitro assays, as well as for its capacity to modify embryonic morphogenetic processes ..
  4. García Casal M, Ramirez J, Leets I, Pereira A, Quiroga M. Antioxidant capacity, polyphenol content and iron bioavailability from algae (Ulva sp., Sargassum sp. and Porphyra sp.) in human subjects. Br J Nutr. 2009;101:79-85 pubmed publisher
    ..A total of eighty-three subjects received maize- or wheat-based meals containing marine algae (Ulva sp., Sargassum sp. and Porphyra sp.) in different proportions (2.5, 5.0 and 7.5 g) added to the water to prepare the dough...
  5. Ale M, Maruyama H, Tamauchi H, Mikkelsen J, Meyer A. Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivo. Int J Biol Macromol. 2011;49:331-6 pubmed publisher
    ..In this study, we examined the influence of crude fucoidan extracted from Sargassum sp. (MTA) and Fucus vesiculosus (SIG) on Lewis lung carcinoma cells (LCC) and melanoma B16 cells (MC)...
  6. Ina A, Hayashi K, Nozaki H, Kamei Y. Pheophytin a, a low molecular weight compound found in the marine brown alga Sargassum fulvellum, promotes the differentiation of PC12 cells. Int J Dev Neurosci. 2007;25:63-8 pubmed
    We identified and characterized a neurodifferentiation compound from the marine brown alga Sargassum fulvellum collected from the Japanese coastline. Several instrumental analyses revealed the compound to be pheophytin a...
  7. Naddafi K, Nabizadeh R, Saeedi R, Mahvi A, Vaezi F, Yaghmaeian K, et al. Biosorption of lead(II) and cadmium(II) by protonated Sargassum glaucescens biomass in a continuous packed bed column. J Hazard Mater. 2007;147:785-91 pubmed
    Biosorption of lead(II) and cadmium(II) from aqueous solutions by protonated Sargassum glaucescens biomass was studied in a continuous packed bed column...
  8. Chen X, Nie W, Yu G, Li Y, Hu Y, Lu J, et al. Antitumor and immunomodulatory activity of polysaccharides from Sargassum fusiforme. Food Chem Toxicol. 2012;50:695-700 pubmed publisher
    b>Sargassum fusiforme (Harv.) Setchel is an ingredient of Chinese herbal medicine that has been applied for thousands of years...
  9. Reddy P, Urban S. Meroditerpenoids from the southern Australian marine brown alga Sargassum fallax. Phytochemistry. 2009;70:250-5 pubmed publisher
    Chemical investigation of the southern Australian marine brown alga Sargassum fallax resulted in the isolation of three meroditerpenoids fallahydroquinone, fallaquinone and fallachromenoic acid together with the previously reported ..

More Information

Publications87

  1. Yang L, Chen J. Biosorption of hexavalent chromium onto raw and chemically modified Sargassum sp. Bioresour Technol. 2008;99:297-307 pubmed
    ..acid, sodium hydroxide, calcium chloride, formaldehyde, and glutaraldehyde were used for modification of raw Sargassum sp...
  2. Sarithakumari C, Renju G, Kurup G. Anti-inflammatory and antioxidant potential of alginic acid isolated from the marine algae, Sargassum wightii on adjuvant-induced arthritic rats. Inflammopharmacology. 2013;21:261-8 pubmed publisher
    ..study evaluated the anti-inflammatory and antioxidant potential of alginic acid isolated from brown algae Sargassum wightii in arthritic rats...
  3. Bilan M, Grachev A, Shashkov A, Thuy T, Van T, Ly B, et al. Preliminary investigation of a highly sulfated galactofucan fraction isolated from the brown alga Sargassum polycystum. Carbohydr Res. 2013;377:48-57 pubmed publisher
    A fucoidan preparation was isolated from the brown alga Sargassum polycystum (Fucales, Sargassaceae). The preparation was fractionated by anion-exchange chromatography, and two highly sulfated fractions F3 and F4 were obtained...
  4. Kim S, Lee W, Bae G, Kim Y. Anti-diabetic and hypolipidemic effects of Sargassum yezoense in db/db mice. Biochem Biophys Res Commun. 2012;424:675-80 pubmed publisher
    ..Previously, we have reported in vitro effects of Sargassum yezoense (SY) and its ingredients, sargaquinoic acid (SQA) and sargahydroquinoic acid (SHQA), on PPAR?/? dual ..
  5. Suresh V, Anbazhagan C, Thangam R, Senthilkumar D, Senthilkumar N, Kannan S, et al. Stabilization of mitochondrial and microsomal function of fucoidan from Sargassum plagiophyllum in diethylnitrosamine induced hepatocarcinogenesis. Carbohydr Polym. 2013;92:1377-85 pubmed publisher
    Crude fucoidan from Sargassum plagiophyllum extracted from blade and purified by Q-Sepharose fast flow anion-exchange chromatography and three fucoidan fractions were obtained...
  6. Kim M, Kwon H, Kim S, Kim H, Um B. Plastoquinones from Sargassum yezoense; chemical structures and effects on the activation of peroxisome proliferator-activated receptor gamma. Chem Pharm Bull (Tokyo). 2011;59:834-8 pubmed
    ..with two known compounds, sargahydroquinoic acid and sargaquinoic acid, were isolated from the brown alga, Sargassum yezoense collected from the eastern coast of Korea...
  7. Syad A, Shunmugiah K, Kasi P. Antioxidant and anti-cholinesterase activity of Sargassum wightii. Pharm Biol. 2013;51:1401-10 pubmed publisher
    b>Sargassum has been used in traditional Chinese medicine since the eighth century AD to treat goiter. Sargassum wightii Greville (Sargassaceae) is a major source of alginic acid used widely in food and drug industries...
  8. Thinh P, Menshova R, Ermakova S, Anastyuk S, Ly B, Zvyagintseva T. Structural characteristics and anticancer activity of fucoidan from the brown alga Sargassum mcclurei. Mar Drugs. 2013;11:1456-76 pubmed publisher
    Three different fucoidan fractions were isolated and purified from the brown alga, Sargassum mcclurei. The SmF1 and SmF2 fucoidans are sulfated heteropolysaccharides that contain fucose, galactose, mannose, xylose and glucose...
  9. Ebrahimi M, Panahi R, Dabbagh R. Evaluation of native and chemically modified Sargassum glaucescens for continuous biosorption of Co(II). Appl Biochem Biotechnol. 2009;158:736-46 pubmed publisher
    ..In the present study, biosorption of stable cobalt was studied in an up-flow fixed-bed column using the brown alga Sargassum glaucescens treated with formaldehyde (FA) or MgCl2...
  10. Diniz V, Volesky B. Biosorption of La, Eu and Yb using Sargassum biomass. Water Res. 2005;39:239-47 pubmed
    ..La(3+)), Europium (Eu(3+)) and Ytterbium (Yb(3+)) from single-component and multi-component batch systems using Sargassum polycystum Ca-loaded biomass was studied...
  11. Yokoyama T, Amano M, Sekine M, Homma H, Tokuda M, Sato M. Immunohistochemical localization of endogenous D-Aspartate in the marine brown Alga Sargassum fusiforme. Biosci Biotechnol Biochem. 2011;75:1481-4 pubmed
    Immunohistochemical localization (cellular localization) of endogenous D-aspartate in the marine brown alga Sargassum fusiforme was investigated by the use of a specific polyclonal antibody raised against D-aspartate...
  12. Josephine A, Nithya K, Amudha G, Veena C, Preetha S, Varalakshmi P. Role of sulphated polysaccharides from Sargassum Wightii in Cyclosporine A-induced oxidative liver injury in rats. BMC Pharmacol. 2008;8:4 pubmed publisher
    ..investigation suggests the therapeutic potential of sulphated polysaccharides from marine brown algae "Sargassum wightii" in Cyclosporine A (CsA)- induced liver injury...
  13. Cheang C, Chu K, Ang P. Phylogeography of the marine macroalga Sargassum hemiphyllum (Phaeophyceae, Heterokontophyta) in northwestern Pacific. Mol Ecol. 2010;19:2933-48 pubmed publisher
    b>Sargassum hemiphyllum is commonly found in Japan and Korea, with a variety, var. chinense, that is found distributed in the southern Chinese coast...
  14. Hoey A, Bellwood D. Suppression of herbivory by macroalgal density: a critical feedback on coral reefs?. Ecol Lett. 2011;14:267-73 pubmed publisher
    ..Using transplanted Sargassum, the largest coral reef macroalga, we created habitat patches of predetermined macroalgal density (0.25-6...
  15. Gwon W, Lee M, Kim J, Kim J, Lim C, Kim N, et al. Hexane fraction from Sargassum fulvellum inhibits lipopolysaccharide-induced inducible nitric oxide synthase expression in RAW 264.7 cells via NF-?B pathways. Am J Chin Med. 2013;41:565-84 pubmed publisher
    b>Sargassum fulvellum (Turner) C. Agardh has been used to treat various inflammatory diseases, including lump, dropsy, swollen and painful scrotum, and urination problems for several centuries with no side effects...
  16. Raghavendran H, Sathivel A, Devaki T. Effect of Sargassum polycystum (Phaeophyceae)-sulphated polysaccharide extract against acetaminophen-induced hyperlipidemia during toxic hepatitis in experimental rats. Mol Cell Biochem. 2005;276:89-96 pubmed
    The effect of Sargassum polycystum crude extract on lipid metabolism was examined against acetaminophen-induced (800 mg/kg body wt., intraperitoneally) hyperlipidemia during toxic hepatitis in experimental rats...
  17. Kang G, Han S, Yoon W, Koh Y, Hyun J, Kang H, et al. Sargaquinoic acid isolated from Sargassum siliquastrum inhibits lipopolysaccharide-induced nitric oxide production in macrophages via modulation of nuclear factor-?B and c-Jun N-terminal kinase pathways. Immunopharmacol Immunotoxicol. 2013;35:80-7 pubmed publisher
    ..This study investigated whether sargaquinoic acid isolated from Sargassum siliquastrum might have anti-inflammatory activity and interfere with NO production in macrophages by disrupting ..
  18. Dabbagh R, Ebrahimi M, Aflaki F, Ghafourian H, Sahafipour M. Biosorption of stable cesium by chemically modified biomass of Sargassum glaucescens and Cystoseira indica in a continuous flow system. J Hazard Mater. 2008;159:354-7 pubmed publisher
    ..Two kinds of brown algae (Sargassum glaucescens and Cystoseira indica) were treated with chemical agents including formaldehyde (FA), glutaraldehyde ..
  19. Plouguerné E, de Souza L, Sassaki G, Cavalcanti J, Villela Romanos M, Da Gama B, et al. Antiviral Sulfoquinovosyldiacylglycerols (SQDGs) from the Brazilian brown seaweed Sargassum vulgare. Mar Drugs. 2013;11:4628-40 pubmed publisher
    Total lipids from the Brazilian brown seaweed Sargassum vulgare were extracted with chloroform/methanol 2:1 and 1:2 (v/v) at room temperature...
  20. Park B, Shin W, Um Y, Cho S, Park G, Yeon D, et al. Selective vasodilatation effect of sargahydroquinoic acid, an active constituent of Sargassum micracanthum, on the basilar arteries of rabbits. Bioorg Med Chem Lett. 2008;18:2624-7 pubmed publisher
    Sargahydroquinoic acid (2), a major active constituent of Sargassum micracanthum collected from the coast of the East Sea in Korea, showed a selective vasodilatation effect on the basilar arteries of rabbits...
  21. Karthikeyan S, Balasubramanian R, Iyer C. Evaluation of the marine algae Ulva fasciata and Sargassum sp. for the biosorption of Cu(II) from aqueous solutions. Bioresour Technol. 2007;98:452-5 pubmed
    In this study, the adsorption properties of two different marine algae (Ulva fasciata (green algae) and Sargassum sp. (brown algae)) were investigated...
  22. Yoon W, Heo S, Han S, Lee H, Kang G, Kang H, et al. Anti-inflammatory effect of sargachromanol G isolated from Sargassum siliquastrum in RAW 264.7 cells. Arch Pharm Res. 2012;35:1421-30 pubmed publisher
    A study on the anti-inflammatory activity of brown alga Sargassum siliquastrum led to the isolation of sargachromanol G (SG)...
  23. Park P, Heo S, Park E, Kim S, Byun H, Jeon B, et al. Reactive oxygen scavenging effect of enzymatic extracts from Sargassum thunbergii. J Agric Food Chem. 2005;53:6666-72 pubmed
    The free radical scavenging activity of water soluble natural antioxidants from Sargassum thunbergii, which is a brown marine alga, was evaluated by examining the radical scavenging activities of the extracts of hydrolyzates from S...
  24. Plouguerné E, Ioannou E, Georgantea P, Vagias C, Roussis V, Hellio C, et al. Anti-microfouling activity of lipidic metabolites from the invasive brown alga Sargassum muticum (Yendo) Fensholt. Mar Biotechnol (NY). 2010;12:52-61 pubmed publisher
    The purification of the chloroform extract from the brown invasive macroalga Sargassum muticum, through a series of chromatographic separations, yielded 12 fractions that were tested against strains of bacteria, microalgae, and fungi ..
  25. Kim J, Ahn B, Kong C, Kim S. Protective effect of chromene isolated from Sargassum horneri against UV-A-induced damage in skin dermal fibroblasts. Exp Dermatol. 2012;21:630-1 pubmed publisher
    ..In this study, chromene compound, sargachromenol, was isolated from Sargassum horneri, and its potency on inhibition of photoageing was investigated in UV-A-irradiated dermal fibroblasts...
  26. Liu L, Heinrich M, Myers S, Dworjanyn S. Towards a better understanding of medicinal uses of the brown seaweed Sargassum in Traditional Chinese Medicine: a phytochemical and pharmacological review. J Ethnopharmacol. 2012;142:591-619 pubmed publisher
    For nearly 2000 years Sargassum spp., a brown seaweed, has been used in Traditional Chinese Medicine (TCM) to treat a variety of diseases including thyroid disease (e.g. goitre).
  27. Diniz V, Weber M, Volesky B, Naja G. Column biosorption of lanthanum and europium by Sargassum. Water Res. 2008;42:363-71 pubmed
    Batch and column biosorption of La(3+) (lanthanum) and Eu(3+) (europium) was studied using protonated Sargassum polycystum biomass...
  28. Zhang R, Luo W, Bi T, Zhou S. Evaluation of antioxidant and immunity-enhancing activities of Sargassum pallidum aqueous extract in gastric cancer rats. Molecules. 2012;17:8419-29 pubmed publisher
    The effect of Sargassum pallidum (brown seaweed) aqueous extract on the immunity function and antioxidant activities in was studied gastric cancer rats...
  29. Hur S, Lee H, Kim Y, Lee B, Shin J, Kim T. Sargaquinoic acid and sargachromenol, extracts of Sargassum sagamianum, induce apoptosis in HaCaT cells and mice skin: Its potentiation of UVB-induced apoptosis. Eur J Pharmacol. 2008;582:1-11 pubmed publisher
    The plastoquinones sargaquinoic acid and sargachromenol are major components of brown alga Sargassum sagamianum and are known to be involved in neurite growth and survival...
  30. Chen X, Nie W, Fan S, Zhang J, Wang Y, Lu J, et al. A polysaccharide from Sargassum fusiforme protects against immunosuppression in cyclophosphamide-treated mice. Carbohydr Polym. 2012;90:1114-9 pubmed publisher
    A water-soluble polysaccharide (SFPS) isolated from Sargassum fusiforme was purified by DEAE-52 cellulose anion-exchange and Sephadex G-200 gel filtration chromatography...
  31. Zhou J, Hu N, Wu Y, Pan Y, Sun C. Preliminary studies on the chemical characterization and antioxidant properties of acidic polysaccharides from Sargassum fusiforme. J Zhejiang Univ Sci B. 2008;9:721-7 pubmed publisher
    In order to investigate the antioxidant properties of the polysaccharides from the brown alga Sargassum fusiforme, the crude polysaccharides from S...
  32. Costa L, Fidelis G, Telles C, Dantas Santos N, Camara R, Cordeiro S, et al. Antioxidant and antiproliferative activities of heterofucans from the seaweed Sargassum filipendula. Mar Drugs. 2011;9:952-66 pubmed publisher
    ..We obtained five heterofucans from Sargassum filipendula by proteolytic digestion followed by sequential acetone precipitation...
  33. Marin A, Casas Valdez M, Carrillo S, Hernández H, Monroy A, Sanginés L, et al. The marine algae Sargassum spp. (Sargassaceae) as feed for sheep in tropical and subtropical regions. Rev Biol Trop. 2009;57:1271-81 pubmed
    The objective of this study was to evaluate Sargassum meal as feed for sheep through the measures of in vivo digestibility, dry matter degradability, pH, ammonia and volatile fatty acids in rumen...
  34. Wu W, Hasumi K, Peng H, Hu X, Wang X, Bao B. Fibrinolytic compounds isolated from a brown alga, Sargassum fulvellum. Mar Drugs. 2009;7:85-94 pubmed publisher
    Two of bioactive natural products were founded in a brown alga, Sargassum fulvellum. After isolation and purification, the molecular structures of these two products were investigated by NMR spectroscopy and GC-mass spectroscopy...
  35. Ryu G, Park S, Kim E, Choi B, Ryu S, Lee B. Cholinesterase inhibitory activity of two farnesylacetone derivatives from the brown alga Sargassum sagamianum. Arch Pharm Res. 2003;26:796-9 pubmed
    Two known farnesylacetone derivatives (1 and 2) were isolated from the Korean brown alga Sargassum sagamianum off Jeju Island, Korea...
  36. Choi B, Ryu G, Park S, Kim E, Shin J, Roh S, et al. Anticholinesterase activity of plastoquinones from Sargassum sagamianum: lead compounds for Alzheimer's disease therapy. Phytother Res. 2007;21:423-6 pubmed
    ..marine organisms, two known plastoquinones, sargaquinoic acid (1) and sargachromenol (2), were isolated from Sargassum sagamianum...
  37. Vijayaraghavan K, Prabu D. Potential of Sargassum wightii biomass for copper(II) removal from aqueous solutions: application of different mathematical models to batch and continuous biosorption data. J Hazard Mater. 2006;137:558-64 pubmed
    This paper reports biosorption of copper(II) ions onto Sargassum wightii biomass in batch and continuous mode of operation. Batch experiments were fundamentally aimed to determine the favorable pH for copper(II) biosorption...
  38. Kim Y, Kim E, Lee C, Kim M, Rho J. Two new monogalactosyl diacylglycerols from brown alga Sargassum thunbergii. Lipids. 2007;42:395-9 pubmed
    ..two known glycolipids were isolated from the moderate polar fraction of the methanolic extract of the brown alga Sargassum thunbergii by using reversed silica flash chromatography...
  39. Afolayan A, Bolton J, Lategan C, Smith P, Beukes D. Fucoxanthin, tetraprenylated toluquinone and toluhydroquinone metabolites from Sargassum heterophyllum inhibit the in vitro growth of the malaria parasite Plasmodium falciparum. Z Naturforsch C. 2008;63:848-52 pubmed
    ..acid, sargahydroquinoic acid, sargaquinal and fucoxanthin, were isolated from the South African alga Sargassum heterophyllum...
  40. Costa L, Telles C, Oliveira R, Nobre L, Dantas Santos N, Camara R, et al. Heterofucan from Sargassum filipendula induces apoptosis in HeLa cells. Mar Drugs. 2011;9:603-14 pubmed publisher
    ..Heterofucan SF-1.5v was extracted from the brown seaweed Sargassum filipendula by proteolytic digestion followed by sequential acetone precipitation...
  41. Lee D, Lin X, Paskaleva E, Liu Y, Puttamadappa S, Thornber C, et al. Palmitic Acid Is a Novel CD4 Fusion Inhibitor That Blocks HIV Entry and Infection. AIDS Res Hum Retroviruses. 2009;25:1231-41 pubmed publisher
    ..We investigated a large number of natural products, and from Sargassum fusiforme we isolated and identified palmitic acid (PA) as a natural small bioactive molecule with activity ..
  42. Dias P, Siqueira J, Vendruscolo L, de Jesus Neiva T, Gagliardi A, Maraschin M, et al. Antiangiogenic and antitumoral properties of a polysaccharide isolated from the seaweed Sargassum stenophyllum. Cancer Chemother Pharmacol. 2005;56:436-46 pubmed
    ..antiangiogenic and antitumoral properties of SargA, a polysaccharide extracted from the brown marine alga Sargassum stenophyllum, were studied in assays carried out in chick embryos and mice...
  43. Heo S, Yoon W, Kim K, Oh C, Choi Y, Yoon K, et al. Anti-inflammatory effect of fucoxanthin derivatives isolated from Sargassum siliquastrum in lipopolysaccharide-stimulated RAW 264.7 macrophage. Food Chem Toxicol. 2012;50:3336-42 pubmed publisher
    In this study, the anti-inflammatory effect of fucoxanthin (FX) derivatives, which was isolated from Sargassum siliquastrum were evaluated by examining their inhibitory effects on pro-inflammatory mediators in lipopolysaccharide (LPS)-..
  44. Cruz C, da Costa A, Henriques C, Luna A. Kinetic modeling and equilibrium studies during cadmium biosorption by dead Sargassum sp. biomass. Bioresour Technol. 2004;91:249-57 pubmed
    A basic investigation on the removal of cadmium(II) ions from aqueous solutions by dead Sargassum sp. was conducted in batch conditions...
  45. Chan Y, Kim K, Cheah S. Inhibitory effects of Sargassum polycystum on tyrosinase activity and melanin formation in B16F10 murine melanoma cells. J Ethnopharmacol. 2011;137:1183-8 pubmed publisher
    b>Sargassum polycystum, a type of brown seaweed, has been used for the treatment of skin-related disorders in traditional medicine.
  46. Phillips J, Blackshaw J. Extirpation of macroalgae (Sargassum spp.) on the subtropical east Australian coast. Conserv Biol. 2011;25:913-21 pubmed publisher
    ..b>Sargassum amaliae, S. aquifolium, S. carpophyllum, S. polycystum, and S...
  47. Williams A, Feagin R. Sargassum as a natural solution to enhance dune plant growth. Environ Manage. 2010;46:738-47 pubmed publisher
    ..One such practice is mechanical beach raking in which the wrack line is removed from the beach front. In Texas, Sargassum fluitans and natans, types of brown alga, are the main components of wrack and may provide a subsidy to the ..
  48. Dore C, das C Faustino Alves M, Will L, Costa T, Sabry D, de Souza Rêgo L, et al. A sulfated polysaccharide, fucans, isolated from brown algae Sargassum vulgare with anticoagulant, antithrombotic, antioxidant and anti-inflammatory effects. Carbohydr Polym. 2013;91:467-75 pubmed publisher
    Fucan (SV1) sulfated polysaccharides from the brown algae Sargassum vulgare were extracted, fractionated in acetone and examined with respect to chemical composition, anticoagulant, anti-inflammatory, antithrombotic effects and cellular ..
  49. Yeh S, Lee C, Chen J. Administration of hot-water extract of brown seaweed Sargassum duplicatum via immersion and injection enhances the immune resistance of white shrimp Litopenaeus vannamei. Fish Shellfish Immunol. 2006;20:332-45 pubmed
    ..42+/-1.39 g) were immersed in seawater (34 per thousand) containing hot-water extract of brown alga Sargassum duplicatum at 100, 300 and 500 mg l(-1), or injected with hot-water extract of S...
  50. Kamei Y, Sueyoshi M, Hayashi K, Terada R, Nozaki H. The novel anti-Propionibacterium acnes compound, Sargafuran, found in the marine brown alga Sargassum macrocarpum. J Antibiot (Tokyo). 2009;62:259-63 pubmed publisher
    ..found a novel antibacterial compound, which we named Sargafuran, from the MeOH extract of the marine brown alga, Sargassum macrocarpum. Sargafuran has low cytotoxicity, and the MIC against P...
  51. Powers S, Hernandez F, Condon R, Drymon J, Free C. Novel pathways for injury from offshore oil spills: direct, sublethal and indirect effects of the Deepwater Horizon oil spill on pelagic Sargassum communities. PLoS ONE. 2013;8:e74802 pubmed publisher
    The pelagic brown alga Sargassum forms an oasis of biodiversity and productivity in an otherwise featureless ocean surface...
  52. Coelho Souza S, Miranda M, Salgado L, Coutinho R, Guimarães J. Adaptation of the 3H-leucine incorporation technique to measure heterotrophic activity associated with biofilm on the blades of the seaweed Sargassum spp. Microb Ecol. 2013;65:424-36 pubmed publisher
    ..incorporation technique to measure bacterial activity in biofilms associated with the blades of the macroalgae Sargassum spp...
  53. Hayashi K, Mori J, Saito H, Hayashi T. Antiviral targets of a chromene derivative from Sargassum micracanthum in the replication of human cytomegalovirus. Biol Pharm Bull. 2006;29:1843-7 pubmed
    A chromene derivative (1) obtained from a brown alga, Sargassum micracanthum, has been proved to be a potent inhibitor of human cytomegalovirus (HCMV). In the present study, we evaluated its mode of action by various experimental assays...
  54. Tsang C, Ina A, Goto T, Kamei Y. Sargachromenol, a novel nerve growth factor-potentiating substance isolated from Sargassum macrocarpum, promotes neurite outgrowth and survival via distinct signaling pathways in PC12D cells. Neuroscience. 2005;132:633-43 pubmed
    We previously found that the methanol extract of a marine brown alga, Sargassum macrocarpum showed marked nerve growth factor (NGF)-dependent neurite outgrowth promoting activity to PC12D cells...
  55. Mahdavi M, Namvar F, Ahmad M, Mohamad R. Green biosynthesis and characterization of magnetic iron oxide (Fe?O?) nanoparticles using seaweed (Sargassum muticum) aqueous extract. Molecules. 2013;18:5954-64 pubmed publisher
    ..step and completely green biosynthetic method by reduction of ferric chloride solution with brown seaweed (BS, Sargassum muticum) water extract containing sulphated polysaccharides as a main factor which acts as reducing agent and ..
  56. Na H, Moon P, Ko S, Lee H, Jung H, Hong S, et al. Sargassum hemiphyllum inhibits atopic allergic reaction via the regulation of inflammatory mediators. J Pharmacol Sci. 2005;97:219-26 pubmed
    b>Sargassum hemiphyllum (SH) has long been used in Korean folk medicine for the therapeutic treatment of various allergic diseases. The effects of SH in previous experimental models, however, have been inconclusive...
  57. Permeh P, Saeidnia S, Mashinchian Moradi A, Gohari A. Sterols from Sargassum oligocystum, a brown algae from the Persian Gulf, and their bioactivity. Nat Prod Res. 2012;26:774-7 pubmed publisher
    b>Sargassum oligocystum (Heterokontophyta) is one of the most abundant algae distributed in the Persian Gulf...
  58. Zandi K, Ahmadzadeh S, Tajbakhsh S, Rastian Z, Yousefi F, Farshadpour F, et al. Anticancer activity of Sargassum oligocystum water extract against human cancer cell lines. Eur Rev Med Pharmacol Sci. 2010;14:669-73 pubmed
    ..This study was designed to assay antitumor activity of the extract from brown alga Sargassum oligocystum, gathered from Persian Gulf seashore, against K562 and Daudi human cancer cell lines.
  59. Paskaleva E, Lin X, Duus K, McSharry J, Veille J, Thornber C, et al. Sargassum fusiforme fraction is a potent and specific inhibitor of HIV-1 fusion and reverse transcriptase. Virol J. 2008;5:8 pubmed publisher
    b>Sargassum fusiforme (Harvey) Setchell has been shown to be a highly effective inhibitor of HIV-1 infection. To identify its mechanism of action, we performed bioactivity-guided fractionation on Sargassum fusiforme mixture...
  60. Jung M, Jang K, Kim B, Lee B, Choi B, Oh K, et al. Meroditerpenoids from the brown alga Sargassum siliquastrum. J Nat Prod. 2008;71:1714-9 pubmed publisher
    ..7-11, 14-17, 19, 20) and nine known compounds (1-6, 12, 13, 18) were isolated from the brown alga Sargassum siliquastrum...
  61. Josephine A, Amudha G, Veena C, Preetha S, Rajeswari A, Varalakshmi P. Beneficial effects of sulfated polysaccharides from Sargassum wightii against mitochondrial alterations induced by Cyclosporine A in rat kidney. Mol Nutr Food Res. 2007;51:1413-22 pubmed
  62. Namvar F, Mohamad R, Baharara J, Zafar Balanejad S, Fargahi F, Rahman H. Antioxidant, antiproliferative, and antiangiogenesis effects of polyphenol-rich seaweed (Sargassum muticum). Biomed Res Int. 2013;2013:604787 pubmed publisher
    In the present study, we evaluated the effect of brown seaweeds Sargassum muticum methanolic extract (SMME), against MCF-7 and MDA-MB-231 breast cancer cell lines proliferation...
  63. Gamal Eldeen A, Ahmed E, Abo Zeid M. In vitro cancer chemopreventive properties of polysaccharide extract from the brown alga, Sargassum latifolium. Food Chem Toxicol. 2009;47:1378-84 pubmed publisher
    Polysaccharides of edible algae attracted extensive interest due to their numerous biological activities. Sargassum latifolium (Turner) C. Agardh, belongs to Sargassaceae, is a brown algae in red sea shores in Egypt...
  64. Picardo M, de Melo Ferreira A, Augusto da Costa A. Biosorption of radioactive thorium by Sargassum filipendula. Appl Biochem Biotechnol. 2006;134:193-206 pubmed
    In the present work, the biosorption of radioactive thorium was investigated using a dry biomass of Sargassum filipendula as the biosorbent material. Radioactive solutions containing between 2.0 and 500...
  65. Sinha S, Astani A, Ghosh T, Schnitzler P, Ray B. Polysaccharides from Sargassum tenerrimum: structural features, chemical modification and anti-viral activity. Phytochemistry. 2010;71:235-42 pubmed publisher
    ..to inhibiting HSV infection by using a sulfated fucoidan, and a guluronic acid-rich alginate derived from Sargassum tenerrimum, mimicking the active domain of the entry receptor...
  66. Ji Y, Gao S, Zhang X. [Influence of sargassum fusiforme polysaccharide on apoptosis of tumor cells]. Zhongguo Zhong Yao Za Zhi. 2004;29:245-7 pubmed
    To study mechanism of antitumor activity of Sargassum Fusiforme Polysaccharide (SFPS).
  67. Thibaut T, Pinedo S, Torras X, Ballesteros E. Long-term decline of the populations of Fucales (Cystoseira spp. and Sargassum spp.) in the Albères coast (France, North-western Mediterranean). Mar Pollut Bull. 2005;50:1472-89 pubmed
    ..tenuiramosa, Cystoseira spinosa, Cystoseira spinosa var. compressa, Sargassum hornschuchii and Sargassum vulgare) were considered frequent and some of them were the dominant and engineering ..
  68. Matanjun P, Mohamed S, Muhammad K, Mustapha N. Comparison of cardiovascular protective effects of tropical seaweeds, Kappaphycus alvarezii, Caulerpa lentillifera, and Sargassum polycystum, on high-cholesterol/high-fat diet in rats. J Med Food. 2010;13:792-800 pubmed publisher
    ..and brown tropical seaweeds, namely, Kappaphycus alvarezii (or Eucheuma cottonii), Caulerpa lentillifera, and Sargassum polycystum, in rats fed on high-cholesterol/high-fat (HCF) diets...
  69. Esmaeili A, Ghasemi S, Sohrabipour J. Biosorption of copper from wastewater by activated carbon preparation from alga Sargassum sp. Nat Prod Res. 2010;24:341-8 pubmed publisher
    ..this study, the batch removal of copper(II) ions from an aqueous solution and wastewater using marine brown alga Sargassum sp. was investigated. Activated carbon prepared from Sargassum sp...
  70. Kim J, Kong C, Kim S. Effect of Sargassum thunbergii on ROS mediated oxidative damage and identification of polyunsaturated fatty acid components. Food Chem Toxicol. 2010;48:1243-9 pubmed publisher
    In this study, we examined protective effect of Sargassum thunbergii on reactive oxygen species (ROS) mediated oxidative stress in cellular systems. In addition, polyunsaturated fatty acids from S...
  71. Kim S, Choi H, Lee W, Park G, Shin W, Kim Y. Sargaquinoic acid and sargahydroquinoic acid from Sargassum yezoense stimulate adipocyte differentiation through PPARalpha/gamma activation in 3T3-L1 cells. FEBS Lett. 2008;582:3465-72 pubmed publisher
    ..Sargaquinoic acid (SQA) and sargahydroquinoic acid (SHQA) from Sargassum yezoense were identified as novel PPARalpha/gamma dual agonists...
  72. Qi S, Zhang S, Huang J, Xiao Z, Wu J, Long L. Glycerol derivatives and sterols from Sargassum parvivesiculosum. Chem Pharm Bull (Tokyo). 2004;52:986-8 pubmed
    ..glycerol derivatives (1-5) and three sterols (6-8) were isolated from the EtOH extraction of the brown alga of Sargassum parvivesiculosum...
  73. Heo S, Jeon Y. Protective effect of fucoxanthin isolated from Sargassum siliquastrum on UV-B induced cell damage. J Photochem Photobiol B. 2009;95:101-7 pubmed publisher
    Fucoxanthin is a carotenoid isolated from Sargassum siliquastrum and is considered to be one of major active compound of marine algae...
  74. Hu Z, Uwai S, Yu S, Komatsu T, Ajisaka T, Duan D. Phylogeographic heterogeneity of the brown macroalga Sargassum horneri (Fucaceae) in the northwestern Pacific in relation to late Pleistocene glaciation and tectonic configurations. Mol Ecol. 2011;20:3894-909 pubmed publisher
    ..and contemporary factors affected genetic connectivity, phylogeographic profiles of littoral macroalga Sargassum horneri in the ANP were analysed based on mitochondrial (Cox3) and chloroplast (rbcL) data sets...
  75. Kang J, Khan M, Park N, Cho J, Lee M, Fujii H, et al. Antipyretic, analgesic, and anti-inflammatory activities of the seaweed Sargassum fulvellum and Sargassum thunbergii in mice. J Ethnopharmacol. 2008;116:187-90 pubmed
    Dichloromethane, ethanol, and boiling water extracts of the brown seaweeds Sargassum fulvellum and Sargassum thunbergii were examined for antipyretic, analgesic, and anti-inflammatory activities in mice...
  76. Zhang C, Wu W, Wang J, Lan M. Antioxidant properties of polysaccharide from the brown seaweed Sargassum graminifolium (Turn.), and its effects on calcium oxalate crystallization. Mar Drugs. 2012;10:119-30 pubmed publisher
    We investigated the effects of polysaccharides from the brown seaweed Sargassum graminifolium (Turn.) (SGP) on calcium oxalate crystallization, and determined its antioxidant activities...
  77. Singaravelu G, Arockiamary J, Kumar V, Govindaraju K. A novel extracellular synthesis of monodisperse gold nanoparticles using marine alga, Sargassum wightii Greville. Colloids Surf B Biointerfaces. 2007;57:97-101 pubmed
    ..In the present, work we have investigated extracellular biosynthesis of gold nanoparticles using Sargassum wightii and have achieved rapid formation of gold nanoparticles in a short duration...
  78. Josephine A, Veena C, Amudha G, Preetha S, Sundarapandian R, Varalakshmi P. Sulphated polysaccharides: new insight in the prevention of cyclosporine A-induced glomerular injury. Basic Clin Pharmacol Toxicol. 2007;101:9-15 pubmed
    ..These findings underline that restoration of normal cells accredits sulphated polysaccharides, from Sargassum wightii, with nephroprotective role, against cyclosporine A-induced renal injury.