urtica dioica

Summary

Summary: A plant species of the genus Urtica, family URTICACEAE. Roots have been used to treat PROSTATIC HYPERPLASIA. Leaves are edible after the stinging quality is eliminated by brief heating.

Top Publications

  1. Awad E, Austin B. Use of lupin, Lupinus perennis, mango, Mangifera indica, and stinging nettle, Urtica dioica, as feed additives to prevent Aeromonas hydrophila infection in rainbow trout, Oncorhynchus mykiss (Walbaum). J Fish Dis. 2010;33:413-20 pubmed publisher
    ..Oncorhynchus mykiss (Walbaum), with 1% lupin, Lupinus perennis, mango, Mangifera indica, or stinging nettle, Urtica dioica, for 14 days led to reductions in mortality after challenge with Aeromonas hydrophila...
  2. Harata K, Schubert W, Muraki M. Structure of Urtica dioica agglutinin isolectin I: dimer formation mediated by two zinc ions bound at the sugar-binding site. Acta Crystallogr D Biol Crystallogr. 2001;57:1513-7 pubmed
  3. Gul N, Ahmed S, Smith L. Inhibition of the protease activity of the light chain of type A botulinum neurotoxin by aqueous extract from stinging nettle (Urtica dioica) leaf. Basic Clin Pharmacol Toxicol. 2004;95:215-9 pubmed
    ..The inhibition mode of water soluble fraction against protease activity of type A light chain was analyzed and found to be a non-competitive...
  4. Gathmann A, Wirooks L, Eckert J, Schuphan I. Spatial distribution of Aglais urticae (L.) and its host plant Urtica dioica (L.) in an agricultural landscape: implications for Bt maize risk assessment and post-market monitoring. Environ Biosafety Res. 2006;5:27-36 pubmed
    ..results showed that larvae of the small tortoiseshell developed primarily on freshly sprouted nettle stands (Urtica dioica (L.)) in field margins, rather than adjacent to hedges and groves...
  5. Oñate M, Munné Bosch S. Influence of plant maturity, shoot reproduction and sex on vegetative growth in the dioecious plant Urtica dioica. Ann Bot. 2009;104:945-56 pubmed publisher
    Stinging nettle (Urtica dioica) is a herbaceous, dioecious perennial that is widely distributed around the world, reproduces both sexually and asexually, and is characterized by rapid growth...
  6. Kanter M, Meral I, Dede S, Gunduz H, Cemek M, Ozbek H, et al. Effects of Nigella sativa L. and Urtica dioica L. on lipid peroxidation, antioxidant enzyme systems and some liver enzymes in CCl4-treated rats. J Vet Med A Physiol Pathol Clin Med. 2003;50:264-8 pubmed
    This study was designed to investigate the effects Nigella sativa L. (NS) and Urtica dioica L. (UD) on lipid peroxidation, antioxidant enzyme systems and some liver enzymes in carbon tetrachloride (CCl4)-treated rats...
  7. Ji T, Liu C, Wang A, Yang J, Su Y, Yuan L, et al. [Studies on the chemical constituents of Urtica dioica L. grown in Tibet Autonomous Region]. Zhong Yao Cai. 2007;30:662-4 pubmed
    Studies on the whole herb of Urtica dioica L...
  8. Akbay P, Basaran A, Undeğer U, Basaran N. In vitro immunomodulatory activity of flavonoid glycosides from Urtica dioica L. Phytother Res. 2003;17:34-7 pubmed
    The major compounds isolated from the methanolic extract of the aerial parts of Urtica dioica L. were determined as quercetin-3-O-rutinoside (1). kaempherol-3-O-rutinoside (2). and isorhamnetin-3-O-glucoside (3)...
  9. Yener Z, Celik I, Ilhan F, Bal R. Effects of Urtica dioica L. seed on lipid peroxidation, antioxidants and liver pathology in aflatoxin-induced tissue injury in rats. Food Chem Toxicol. 2009;47:418-24 pubmed publisher
    This study was carried out to investigate the hepatoprotective and antioxidant properties of Urtica dioica L. seeds (UDS) extract against aflatoxin (AF)-exposure in rats...

More Information

Publications85

  1. Namazi N, Esfanjani A, Heshmati J, Bahrami A. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial. Pak J Biol Sci. 2011;14:775-9 pubmed
    ..In this study, hydro alcoholic extract of Nettle (Urtica dioica) on insulin sensitivity and some inflammatory indicators in type 2 diabetic patients were studied...
  2. Jahanshahi M, Golalipour M, Afshar M. The effect of Urtica dioica extract on the number of astrocytes in the dentate gyrus of diabetic rats. Folia Morphol (Warsz). 2009;68:93-7 pubmed
    ..These alterations include abnormal expression of hypothalamic neuropeptides and hippocampal astrogliosis. Urtica dioica (Nettle) is among several species listed for their use against diabetes in folk medicine...
  3. Pinelli P, Ieri F, Vignolini P, Bacci L, Baronti S, Romani A. Extraction and HPLC analysis of phenolic compounds in leaves, stalks, and textile fibers of Urtica dioica L. J Agric Food Chem. 2008;56:9127-32 pubmed publisher
    In the present study the phenolic composition of leaves, stalks, and textile fiber extracts from Urtica dioica L. is described...
  4. Testai L, Chericoni S, Calderone V, Nencioni G, Nieri P, Morelli I, et al. Cardiovascular effects of Urtica dioica L. (Urticaceae) roots extracts: in vitro and in vivo pharmacological studies. J Ethnopharmacol. 2002;81:105-9 pubmed
    b>Urtica dioica (Urticaceae) is a plant principally used in the traditional medicine of oriental Marocco as antihypertensive remedy (J. Ethnopharmacol., 58 (1997), 45)...
  5. Khalifeh M, Hananeh W, Al Rukibat R, Okour O, Boumezrag A. Clinical and histopathological evaluation of MDP/collagen induced arthritis rat model (MCIA) after treatment with Urtica dioica, plantago major and Hypericum perforatum L herbal mixture. Exp Anim. 2008;57:101-10 pubmed
    This study was done to assess the effects of Urtica dioica, Plantago major and Hypericum perforatum L herbal mixture in the MCIA rat model. In addition, a new pathological and clinical arthritis lesion assessment was developed...
  6. Oguz S, Kanter M, Erboga M, Ibis C. Protective effect of Urtica dioica on liver damage induced by biliary obstruction in rats. Toxicol Ind Health. 2013;29:838-45 pubmed publisher
    The aim of this study was to evaluate the possible protective effects of Urtica dioica (UD) against liver damage in the common bile duct-ligated rats...
  7. Krystofova O, Adam V, Babula P, Zehnalek J, Beklova M, Havel L, et al. Effects of various doses of selenite on stinging nettle (Urtica dioica L.). Int J Environ Res Public Health. 2010;7:3804-15 pubmed publisher
    ..and possible mechanisms of Se transport in certain parts (roots, leaves, stamp and apex) of nettle (Urtica dioica L.) plants. Se was supplemented by one-shot and two repeated doses to the soil (2.0 and 4...
  8. Daher C, Baroody K, Baroody G. Effect of Urtica dioica extract intake upon blood lipid profile in the rats. Fitoterapia. 2006;77:183-8 pubmed
    Aqueous (150 mg/kg/day) and to a lesser extent petroleum ether (20 mg/kg/day) extract of Urtica dioica given for 30 days to rats fed with normal or high-fat diet, improved the blood lipid profile...
  9. Safarinejad M. Urtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover study. J Herb Pharmacother. 2005;5:1-11 pubmed
    To determine the effects of therapy with Urtica dioica for symptomatic relief of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH).
  10. Domola M, Vu V, Robson Doucette C, Sweeney G, Wheeler M. Insulin mimetics in Urtica dioica: structural and computational analyses of Urtica dioica extracts. Phytother Res. 2010;24 Suppl 2:S175-82 pubmed publisher
    b>Urtica Dioica (UD) is a plant shown to reduce blood glucose levels upon oral ingestion; however, neither its active component nor its mechanism of action has been identified...
  11. Kanter M, Coskun O, Budancamanak M. Hepatoprotective effects of Nigella sativa L and Urtica dioica L on lipid peroxidation, antioxidant enzyme systems and liver enzymes in carbon tetrachloride-treated rats. World J Gastroenterol. 2005;11:6684-8 pubmed
    To investigate the effects of Nigella sativa L (NS) and Urtica dioica L (UD) on lipid peroxidation, antioxidant enzyme systems and liver enzymes in CCl(4)-treated rats.
  12. Golalipour M, Khori V. The protective activity of Urtica dioica leaves on blood glucose concentration and beta-cells in streptozotocin-diabetic rats. Pak J Biol Sci. 2007;10:1200-4 pubmed
    This study was done to determine the protective activity of the hydroalcholic extract of Urtica dioica leaves on Hyperglycemia and beta-cells in hyperglycemic rats...
  13. Gjorgieva D, Kadifkova Panovska T, Baceva K, Stafilov T. Assessment of heavy metal pollution in Republic of Macedonia using a plant assay. Arch Environ Contam Toxicol. 2011;60:233-40 pubmed publisher
    Different plant organs (leaves, flowers, stems, or roots) from four plant species-Urtica dioica L. (Urticaceae), Robinia pseudoacacia L...
  14. Cai T, Mazzoli S, Bechi A, Addonisio P, Mondaini N, Pagliai R, et al. Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients: results from a prospective randomised study. Int J Antimicrob Agents. 2009;33:549-53 pubmed publisher
    We report the results of a prospective randomised study to evaluate the therapeutic effect of Serenoa repens, Urtica dioica (ProstaMEV), quercitin and curcumin (FlogMEV) extracts associated with prulifloxacin in patients affected by ..
  15. Roschek B, Fink R, McMichael M, Alberte R. Nettle extract (Urtica dioica) affects key receptors and enzymes associated with allergic rhinitis. Phytother Res. 2009;23:920-6 pubmed publisher
    A nettle (Urtica dioica) extract shows in vitro inhibition of several key inflammatory events that cause the symptoms of seasonal allergies...
  16. Kandis H, Karapolat S, Yildirim U, Saritas A, Gezer S, Memisogullari R. Effects of Urtica dioica on hepatic ischemia-reperfusion injury in rats. Clinics (Sao Paulo). 2010;65:1357-61 pubmed
    To evaluate the effects of Urtica dioica on hepatic ischemia-reperfusion injury.
  17. Harput U, Saracoglu I, Ogihara Y. Stimulation of lymphocyte proliferation and inhibition of nitric oxide production by aqueous Urtica dioica extract. Phytother Res. 2005;19:346-8 pubmed
    The immunomodulatory and antiinflammatory activities of aqueous Urtica dioica extract were investigated for their effect on the mitogenic response of murine splenocytes and nitric oxide production by murine peritoneal macrophages in ..
  18. Legssyer A, Ziyyat A, Mekhfi H, Bnouham M, Tahri A, Serhrouchni M, et al. Cardiovascular effects of Urtica dioica L. in isolated rat heart and aorta. Phytother Res. 2002;16:503-7 pubmed
    b>Urtica dioica L. or Nettle (Urticaceae) is widely used in oriental Morocco to treat hypertension. Aqueous extract of Nettle (AEN) also exerts a hypotensive action in the rat in vivo...
  19. Uncini Manganelli R, Zaccaro L, Tomei P. Antiviral activity in vitro of Urtica dioica L., Parietaria diffusa M. et K. and Sambucus nigra L. J Ethnopharmacol. 2005;98:323-7 pubmed
    Parietaria diffusa M. et K., Urtica dioica L. (Urticaceae) and Sambucus nigra L. (Caprifoliaceae) are plants usually used in popular medicine of central Italy for treating numerous diseases, first of all Herpes zoster...
  20. Durak I, Biri H, Devrim E, Sozen S, Avci A. Aqueous extract of Urtica dioica makes significant inhibition on adenosine deaminase activity in prostate tissue from patients with prostate cancer. Cancer Biol Ther. 2004;3:855-7 pubmed
    Investigation of possible effects of aqueous extract of Urtica dioica leaves on adenosine deaminase activity in prostate tissue from patients with prostate cancer.
  21. Farzami B, Ahmadvand D, Vardasbi S, Majin F, Khaghani S. Induction of insulin secretion by a component of Urtica dioica leave extract in perifused Islets of Langerhans and its in vivo effects in normal and streptozotocin diabetic rats. J Ethnopharmacol. 2003;89:47-53 pubmed
    The blood glucose lowering effect of Urtica dioica (Stinging Nettle) as a medicinal plant has been noted in old writings such as those of Avicenna...
  22. Türkdoğan M, Ozbek H, Yener Z, Tuncer I, Uygan I, Ceylan E. The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats. Phytother Res. 2003;17:942-6 pubmed
    The role of Nigella sativa L. (Ranunculaceae) (NS) and Urtica dioica L. was investigated (UD) in the prevention of carbon tetrachloride (CCl4) induced liver fibrosis and cirrhosis...
  23. Sayhan M, Kanter M, Oguz S, Erboga M. Protective effect of Urtica dioica L. on renal ischemia/reperfusion injury in rat. J Mol Histol. 2012;43:691-8 pubmed publisher
    ..This study was designed to investigate the effect of Urtica dioica L. (UD), in I/R induced renal injury...
  24. Gulcin I, Kufrevioglu O, Oktay M, Buyukokuroglu M. Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.). J Ethnopharmacol. 2004;90:205-15 pubmed
    In this study, water extract of nettle (Urtica dioica L.) (WEN) was studied for antioxidant, antimicrobial, antiulcer and analgesic properties...
  25. Ozen T, Korkmaz H. Modulatory effect of Urtica dioica L. (Urticaceae) leaf extract on biotransformation enzyme systems, antioxidant enzymes, lactate dehydrogenase and lipid peroxidation in mice. Phytomedicine. 2003;10:405-15 pubmed
    ..of two doses (50 and 100 mg/kg body wt given orally for 14 days) of an ethanol-water (80%-20%) extract of Urtica dioica L...
  26. Celik I, Tuluce Y. Elevation protective role of Camellia sinensis and Urtica dioica infusion against trichloroacetic acid-exposed in rats. Phytother Res. 2007;21:1039-44 pubmed
    ..the protective effects of two traditionally used Turkish medicinal plants, Camellia sinensis (CS) and Urtica dioica L. (UD), beverages used against chemical carcinogen trichloroacetic acid (TCA)-exposure in rats...
  27. Ozel Demiralp D, Haznedaroglu I, Akar N. Functional proteomic analysis of Ankaferd® Blood Stopper. Turk J Haematol. 2010;27:70-7 pubmed publisher
    ..mixture of the plants Thymus vulgaris, Glycyrrhiza glabra, Vitis vinifera, Alpinia officinarum, and Urtica dioica. The basic mechanism of action for ABS is the formation of an encapsulated protein network that provides focal ..
  28. Movassaghi M, Hassannejad S. EASTERN DODDER (CUSCUTA MONOGYNA VAHL.) SEED GERMINATION AFFECTED BY SOME HERBACEOUS DISTILLATES. Commun Agric Appl Biol Sci. 2015;80:273-7 pubmed
    ..officinalis, Malva neglecta, Mentha piperita, Mentha pulegium, Rosa damascene, Ziziphora tenuior, and Urtica dioica on seed germination of C. monogyna. Z. tenuior distillate stimulated C...
  29. Beyazit Y, Kurt M, Kekilli M, Goker H, Haznedaroglu I. Evaluation of hemostatic effects of Ankaferd as an alternative medicine. Altern Med Rev. 2010;15:329-36 pubmed
    ..mixture of the plants Thymus vulgaris, Glycyrrhiza glabra, Vitis vinifera, Alpinia officinarum, and Urtica dioica. Through its effects on the endothelium, blood cells, angiogenesis, cellular proliferation, vascular dynamics, ..
  30. Conwell R, Findlay C. Nettle reaction in a horse. Vet Rec. 2008;162:256 pubmed
  31. Arnold E, Benz T, Zapp C, Wink M. Inhibition of Cytosolic Phospholipase A2α (cPLA2α) by Medicinal Plants in Relation to Their Phenolic Content. Molecules. 2015;20:15033-48 pubmed publisher
    ..7 μg/mL), Ononis spinosa (IC50 of 39.4 μg/mL), Urtica dioica (IC50 of 44.32 μg/mL), Betula sp. (IC50 of 58.02 μg/mL), Sanguisorba officinalis (IC50 of 76...
  32. Puustinen S, Koskela T, Mutikainen P. Relatedness affects competitive performance of a parasitic plant (Cuscuta europaea) in multiple infections. J Evol Biol. 2004;17:897-903 pubmed
    ..relatedness affects competition between parasitic plants (Cuscuta europaea) that share common host plants (Urtica dioica). We infected hosts with two parasitic plants that were either half-siblings or nonrelated...
  33. Otles S, Yalcin B. Phenolic compounds analysis of root, stalk, and leaves of nettle. ScientificWorldJournal. 2012;2012:564367 pubmed publisher
    Types of nettles (Urtica dioica) were collected from different regions to analyze phenolic compounds in this research. Nettles are specially grown in the coastal part...
  34. Patel S, Mahindroo N, Udayabanu M. Urtica dioica leaves modulates hippocampal smoothened-glioma associated oncogene-1 pathway and cognitive dysfunction in chronically stressed mice. Biomed Pharmacother. 2016;83:676-686 pubmed publisher
    The present study was aimed to evaluate the effect of Urtica dioica (UD) extract against chronic unpredictable stress (CUS)-induced associative memory dysfunction and attempted to explore the possible mechanism...
  35. Mansoori B, Mohammadi A, Hashemzadeh S, Shirjang S, Baradaran A, Asadi M, et al. Urtica dioica extract suppresses miR-21 and metastasis-related genes in breast cancer. Biomed Pharmacother. 2017;93:95-102 pubmed publisher
    ..An MTT assay and scratch test were used to assess the cytotoxicity and migration effects of Urtica dioica on the breast cancer cells...
  36. Toldy A, Atalay M, Stadler K, Sasvari M, Jakus J, Jung K, et al. The beneficial effects of nettle supplementation and exercise on brain lesion and memory in rat. J Nutr Biochem. 2009;20:974-81 pubmed publisher
    ..The effect of swimming training and that of enriched lab chow containing 1% (w/w) dried nettle (Urtica dioica) leaf on the prevention of severity of brain injury caused by N-methyl-d-aspartate (NMDA) lesion in Wistar ..
  37. Goker H, Haznedaroglu I, Ercetin S, Kirazli S, Akman U, Ozturk Y, et al. Haemostatic actions of the folkloric medicinal plant extract Ankaferd Blood Stopper. J Int Med Res. 2008;36:163-70 pubmed
    ..ABS has the therapeutic potential to be used for the management of haemorrhage and this agent should be investigated further in clinical trials. ..
  38. Uzonur I, Akdeniz G, Katmer Z, Ersoy S. RAPD-PCR and real-time PCR HRM based genetic variation evaluations of Urtica dioica parts, ecotypes and evaluations of morphotypes in Turkey. Afr J Tradit Complement Altern Med. 2013;10:232-45 pubmed
    b>Urtica dioica is an ethnobotanically and medicinally important Complementary and Alternative Medicine (CAM) plant worldwide and in Turkey; 90 % of herbal CAM applications depend on it in Turkey...
  39. Szabo Z, Böddi K, Mark L, Szabo L, Ohmacht R. Analysis of nitrate ion in nettle (Urtica dioica L.) by ion-pair chromatographic method on a C30 stationary phase. J Agric Food Chem. 2006;54:4082-6 pubmed
    ..031-30.66 microg mL(-1)). Recoveries varied between 98% and 103%. Reproducibility of the elaborated sample pretreatment method showed 1.54%. The method can be used for the determination of nitrate ion from different plants. ..
  40. Aydin M, Ozaydin I, Ilce Z, Sahin I, Sencan I, Silan C, et al. Effect of Urtica Dioica on bacterial translocation in mechanic icter model. Saudi Med J. 2006;27:748-9 pubmed
  41. Alhmedi A, Haubruge E, Bodson B, Francis F. Inter- and intra-guild interactions related to aphids in nettle (Urtica dioica L.) strips closed to field crops. Commun Agric Appl Biol Sci. 2006;71:413-23 pubmed
    ..Margin strips of nettle (Urtica dioica) closed to wheat (Triticum aestivum), green pea (Pisum sativum) and rape (Brassicae napus) fields were ..
  42. Omwenga E, Hensel A, Shitandi A, Goycoolea F. Ethnobotanical survey of traditionally used medicinal plants for infections of skin, gastrointestinal tract, urinary tract and the oral cavity in Borabu sub-county, Nyamira county, Kenya. J Ethnopharmacol. 2015;176:508-14 pubmed publisher
    ..Among the 25 species collected from the various regions of Borabu sub-county Urtica dioica L. was the only medicinal plant that was collected from all regions...
  43. Huber R, Bross F, Schempp C, Gründemann C. Arnica and stinging nettle for treating burns - a self-experiment. Complement Ther Med. 2011;19:276-80 pubmed publisher
    ..Combudoron seems to have positive effects on healing of grade 2 laser induced burns which deserve further investigation. ..
  44. Suliburska J, Kaczmarek K. Herbal infusions as a source of calcium, magnesium, iron, zinc and copper in human nutrition. Int J Food Sci Nutr. 2012;63:194-8 pubmed publisher
    ..4-12.4%), while copper did so to the highest (26.7-50.7%). It is felt that in average consumption the herbal infusions are not important as calcium, magnesium, iron, zinc and copper sources in human nutrition. ..
  45. Bondarenko B, Walther C, Funk P, Schläfke S, Engelmann U. Long-term efficacy and safety of PRO 160/120 (a combination of sabal and urtica extract) in patients with lower urinary tract symptoms (LUTS). Phytomedicine. 2003;10 Suppl 4:53-5 pubmed
  46. Cummings A, Olsen M. Mechanism of action of stinging nettles. Wilderness Environ Med. 2011;22:136-9 pubmed publisher
    Inadvertent exposure to the ubiquitous weed, Urtica dioica, called "stinging nettles" produces an immediate stinging and burning sensation on the skin...
  47. Di Lorenzo C, Dell Agli M, Badea M, Dima L, Colombo E, Sangiovanni E, et al. Plant food supplements with anti-inflammatory properties: a systematic review (II). Crit Rev Food Sci Nutr. 2013;53:507-16 pubmed publisher
    ..The review considers six botanical species commonly used as food supplements/medicinals: Urtica dioica L., Symphytum officinalis L., Calendula officinalis L., Curcuma longa L., Boswellia serrata Roxb...
  48. Popa G, Hägele Kaddour H, Walther C. [Benign prostate syndrome: urinary tract symptoms can be eased with phytotherapy]. MMW Fortschr Med. 2005;147:42 pubmed
  49. Nygren G, Nylin S, Stefanescu C. Genetics of host plant use and life history in the comma butterfly across Europe: varying modes of inheritance as a potential reproductive barrier. J Evol Biol. 2006;19:1882-93 pubmed
    ..between Swedish and English populations, the results regarding female oviposition preference (choice between Urtica dioica and Salix caprea) showed X-linked inheritance to be of importance for the variation between Sweden and the ..
  50. Johnson T, Sohn J, Inman W, Bjeldanes L, Rayburn K. Lipophilic stinging nettle extracts possess potent anti-inflammatory activity, are not cytotoxic and may be superior to traditional tinctures for treating inflammatory disorders. Phytomedicine. 2013;20:143-7 pubmed publisher
    Extracts of four plant portions (roots, stems, leaves and flowers) of Urtica dioica (the stinging nettle) were prepared using accelerated solvent extraction (ASE) involving water, hexanes, methanol and dichloromethane...
  51. Nassiri Asl M, Zamansoltani F, Abbasi E, Daneshi M, Zangivand A. Effects of Urtica dioica extract on lipid profile in hypercholesterolemic rats. Zhong Xi Yi Jie He Xue Bao. 2009;7:428-33 pubmed publisher
    To investigate the effects of extract of Urtica dioica, a perennial herb in Iran, on lipid profile in hypercholesterolemic rats.
  52. Khan K, Joergensen R. Decomposition of heavy metal contaminated nettles (Urtica dioica L.) in soils subjected to heavy metal pollution by river sediments. Chemosphere. 2006;65:981-7 pubmed
    ..to evaluate differences in the microbial use of non-contaminated and heavy metal contaminated nettle (Urtica dioica L.) shoot residues in three soils subjected to heavy metal pollution (Zn, Pb, Cu, and Cd) by river sediments...
  53. Yildirim N, Turkoglu S, Ince O, Ince M. Evaluation of antioxidant properties, elemental and phenolic contents composition of wild nettle (Urtica dioica L.) from Tunceli in Turkey. Cell Mol Biol (Noisy-le-grand). 2013;Suppl 59:OL1882-8 pubmed
    Wild nettle (Urtica dioica L.) types were sampled from different geographical regions in Tunceli (Turkey) to determine their mineral, vitamin, phenolic contents and their antioxidant properties. The total phenol varied from 37.419 ± 0...
  54. Hadizadeh I, Peivastegan B, Kolahi M. Antifungal activity of nettle (Urtica dioica L.), colocynth (Citrullus colocynthis L. Schrad), oleander (Nerium oleander L.) and konar (Ziziphus spina-christi L.) extracts on plants pathogenic fungi. Pak J Biol Sci. 2009;12:58-63 pubmed
    Anti-mycotic activity of the ethanol extracts from Nettle (Urtica dioica L.), Colocynth (Citrullus colocynthis L. Schrad), Konar (Ziziphus spina-christi L.) and Oleander (Nerium oleander L...
  55. Singh R, Hussain S, Verma R, Sharma P. Anti-mycobacterial screening of five Indian medicinal plants and partial purification of active extracts of Cassia sophera and Urtica dioica. Asian Pac J Trop Med. 2013;6:366-71 pubmed publisher
    To find out the anti-mycobacterial potential of Cassia sophera (C. sophera), Urtica dioica (U...
  56. Schulze Tanzil G, de S, Behnke B, Klingelhoefer S, Scheid A, Shakibaei M. Effects of the antirheumatic remedy hox alpha--a new stinging nettle leaf extract--on matrix metalloproteinases in human chondrocytes in vitro. Histol Histopathol. 2002;17:477-85 pubmed publisher
    ..Hox alpha is a novel stinging nettle (Urtica dioica/Urtica urens) leaf extract used for treatment of rheumatic diseases...
  57. Dar S, Ganai F, Yousuf A, Balkhi M, Bhat T, Sharma P. Pharmacological and toxicological evaluation of Urtica dioica. Pharm Biol. 2013;51:170-80 pubmed publisher
    Medicinal plants are a largely unexplored source of drug repository. Urtica dioica L. (Urticaceae) is used in traditional medicine to treat diverse conditions.
  58. Farag M, Weigend M, Luebert F, Brokamp G, Wessjohann L. Phytochemical, phylogenetic, and anti-inflammatory evaluation of 43 Urtica accessions (stinging nettle) based on UPLC-Q-TOF-MS metabolomic profiles. Phytochemistry. 2013;96:170-83 pubmed publisher
    Several species of the genus Urtica (especially Urtica dioica, Urticaceae), are used medicinally to treat a variety of ailments...
  59. Bnouham M, Merhfour F, Ziyyat A, Mekhfi H, Aziz M, Legssyer A. Antihyperglycemic activity of the aqueous extract of Urtica dioica. Fitoterapia. 2003;74:677-81 pubmed
    When administered 30 min before glucose loading, the aqueous extract of Urtica dioica (nettle) (250 mg/kg) showed a strong glucose lowering effect. The decrease of glycemia has reached to 33+/-3...
  60. Güllçin I, Kufrevioglu O, Oktay M. Purification and characterization of polyphenol oxidase from nettle (Urtica dioica L.) and inhibitory effects of some chemicals on enzyme activity. J Enzyme Inhib Med Chem. 2005;20:297-302 pubmed
    Polyphenol oxidase (PPO) of nettle (Urtica dioica L.) was extracted and purified through (NH4)2SO4 precipitation, dialysis, and CM-Sephadex ion-exchange chromatography and was used for its characterization...
  61. Baykul T, Alanoglu E, Kocer G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. J Contemp Dent Pract. 2010;11:E088-94 pubmed
    ..To determine the efficacy of the topical application of Ankaferd Blood Stopper (ABS) on hemorrhagic diathesis following dental procedures under different conditions...
  62. Fijałek Z, Sołtyk K, Lozak A, Kominek A, Ostapczuk P. Determination of some micro- and macroelements in preparations made from peppermint and nettle leaves. Pharmazie. 2003;58:480-2 pubmed
    ..In all the samples investigated the content of inorganic elements were below the WHO limit (where existing). Variation coefficients ranged from 0.68% to 10.5% for ICP-MS measurements and from 1.48% to 10.0% for ET-ASS...
  63. Balestrieri E, Ascolani A, Igarashi Y, Oki T, Mastino A, Balzarini J, et al. Inhibition of cell-to-cell transmission of human T-cell lymphotropic virus type 1 in vitro by carbohydrate-binding agents. Antimicrob Agents Chemother. 2008;52:2771-9 pubmed publisher
    ..CBAs) such as the alpha(1,3)/alpha(1,6)mannose-specific Hippeastrum hybrid agglutinin and the GlcNAc-specific Urtica dioica agglutinin, and also the small, nonpeptidic alpha(1,2)-mannose-specific antibiotic pradimicin A, were able to ..
  64. Vahlensieck W. [With alpha blockers, finasteride and nettle root against benign prostatic hyperplasia. Which patients are helped by conservative therapy?]. MMW Fortschr Med. 2002;144:33-6 pubmed
    ..In stage IV disease surgical measures--after prior compensation of renal function--are to the fore...
  65. Nahata A, Saxena A, Suri N, Saxena A, Dixit V. Sphaeranthus indicus induces apoptosis through mitochondrial-dependent pathway in HL-60 cells and exerts cytotoxic potential on several human cancer cell lines. Integr Cancer Ther. 2013;12:236-47 pubmed publisher
    The study was designed to screen Sphaeranthus indicus, Ganoderma lucidum, and Urtica dioica for their anticancer activity against human cancer cell lines. Phytochemical screening of active extracts was also planned.
  66. Konrad A, Mahler M, Arni S, Flogerzi B, Klingelhöfer S, Seibold F. Ameliorative effect of IDS 30, a stinging nettle leaf extract, on chronic colitis. Int J Colorectal Dis. 2005;20:9-17 pubmed
    ..The stinging nettle leaf extract, IDS 30, is an adjuvant remedy in rheumatic diseases dependent on a cytokine suppressive effect. We investigated the effect of IDS 30 on disease activity of murine colitis in different models...
  67. Toldy A, Stadler K, Sasvari M, Jakus J, Jung K, Chung H, et al. The effect of exercise and nettle supplementation on oxidative stress markers in the rat brain. Brain Res Bull. 2005;65:487-93 pubmed
    ..The effect of forced, chronic swimming training, and enriched lab chow containing 1% (w/w) dried nettle (Urtica dioica) leaf were investigated for oxidative stress, inflammation and neurotrophic markers in Wistar rat brains...
  68. Carbonnelle S, Hance T, Migeon A, Baret P, Cros Arteil S, Navajas M. Microsatellite markers reveal spatial genetic structure of Tetranychus urticae (Acari: Tetranychidae) populations along a latitudinal gradient in Europe. Exp Appl Acarol. 2007;41:225-41 pubmed
    ..Mites were collected on Urtica dioica in 6 sampling zones...
  69. Danesi F, Pasini F, Caboni M, D Antuono L, Bordoni A. Traditional foods for health: screening of the antioxidant capacity and phenolic content of selected Black Sea area local foods. J Sci Food Agric. 2013;93:3595-603 pubmed publisher
    ..In this study, carried out within the BaSeFood project, the in vitro total antioxidant capacity (TAC) and phenolic content of 39 BSA traditional foods were determined using different assays...
  70. Körpe D, Iseri O, Sahin F, Cabi E, Haberal M. High-antibacterial activity of Urtica spp. seed extracts on food and plant pathogenic bacteria. Int J Food Sci Nutr. 2013;64:355-62 pubmed publisher
    ..antibacterial activities of methanol (MetOH) and aqueous (dw) leaf (L), root (R) and seed (S) extracts of Urtica dioica L. (Ud; stinging nettle) and Urtica pilulifera L...
  71. Notten M, Oosthoek A, Rozema J, Aerts R. Heavy metal concentrations in a soil-plant-snail food chain along a terrestrial soil pollution gradient. Environ Pollut. 2005;138:178-90 pubmed
    We investigated concentrations of Zn, Cu, Cd and Pb in the compartments of a soil-plant (Urtica dioica)-snail (Cepaea nemoralis) food chain in four polluted locations in the Biesbosch floodplains, the Netherlands, and two reference ..
  72. Mohammadi A, Mansoori B, Aghapour M, Baradaran B. Urtica dioica dichloromethane extract induce apoptosis from intrinsic pathway on human prostate cancer cells (PC3). Cell Mol Biol (Noisy-le-grand). 2016;62:78-83 pubmed
    ..On the other hand, due to traditional uses and availability of Urtica dioica extract, we decided to evaluate the efficacy of this medicinal herb on pc3 prostate cancer cell line...
  73. Namazi N, Tarighat A, Bahrami A. The effect of hydro alcoholic nettle (Urtica dioica) extract on oxidative stress in patients with type 2 diabetes: a randomized double-blind clinical trial. Pak J Biol Sci. 2012;15:98-102 pubmed
  74. Nahata A, Dixit V. Ameliorative effects of stinging nettle (Urtica dioica) on testosterone-induced prostatic hyperplasia in rats. Andrologia. 2012;44 Suppl 1:396-409 pubmed publisher
    The present study investigated the effects of stinging nettle (Urtica dioica L.) (UD) on benign prostatic hyperplasia (BPH) induced by testosterone. In vitro studies were conducted to assess the 5?-reductase inhibitory potential of UD...
  75. Popa G, Hägele Kaddour H, Walther C. [Efficacy of a combined Sabal-urtica preparation in the symptomatic treatment of benign prostatic hyperplasia. Results of a placebo-controlled double-blind study]. MMW Fortschr Med. 2005;147 Suppl 3:103-8 pubmed
    ..The patient's quality of life was also significantly better under PRO 160/120 in comparison with placebo...
  76. Zemmouri H, Sekiou O, Ammar S, El Feki A, Bouaziz M, Messarah M, et al. Urtica dioica attenuates ovalbumin-induced inflammation and lipid peroxidation of lung tissues in rat asthma model. Pharm Biol. 2017;55:1561-1568 pubmed publisher
    To find bioactive medicinal herbs exerting anti-asthmatic activity, we investigated the effect of an aqueous extract of Urtica dioica L. (Urticaceae) leaves (UD), the closest extract to the Algerian traditional use.