eriobotrya

Summary

Summary: A plant genus of the family ROSACEAE that is the source of an edible fruit. Members contain TRITERPENES.

Top Publications

  1. Chen J, Li W, Wu J, Ren B, Zhang H. Hypoglycemic effects of a sesquiterpene glycoside isolated from leaves of loquat (Eriobotrya japonica (Thunb.) Lindl.). Phytomedicine. 2008;15:98-102 pubmed
    ..was isolated from dried leaves of loquat [Eriobotrya japonica (Thunb.) Lindl., Rosaceae]...
  2. Lee C, Wu S, Chen J, Li C, Lo H, Cheng W, et al. Eriobotrya japonica leaf and its triterpenes inhibited lipopolysaccharide-induced cytokines and inducible enzyme production via the nuclear factor-kappaB signaling pathway in lung epithelial cells. Am J Chin Med. 2008;36:1185-98 pubmed
    ..Leaf of Eriobotrya japonica (Pi-Pa-Ye, PPY), a traditional Chinese medicine for the treatment of pulmonary inflammatory diseases, ..
  3. Kim S, Kwon Y, Park W, Jeon H, Shin T. Effect of leaves of Eriobotrya japonica on anaphylactic allergic reaction and production of tumor necrosis factor-alpha. Immunopharmacol Immunotoxicol. 2009;31:314-9 pubmed publisher
    Leaves of Eriobotrya japonica Lindl. (Rosaceae) (LEJL) have been used as traditional medicines for inflammatory diseases and chronic bronchitis. However, its effect on mast cell-mediated anaphylactic reaction is not known...
  4. Wang P, Zhang B, Li X, Xu C, Yin X, Shan L, et al. Ethylene signal transduction elements involved in chilling injury in non-climacteric loquat fruit. J Exp Bot. 2010;61:179-90 pubmed publisher
    Loquat (Eriobotrya japonica Lindl.) is a subtropical fruit, with some cultivars such as 'Luoyangqing' (LYQ) susceptible to chilling injury (CI), while others such as 'Baisha' (BS) are resistant...
  5. Rollinger J, Kratschmar D, Schuster D, Pfisterer P, Gumy C, Aubry E, et al. 11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches. Bioorg Med Chem. 2010;18:1507-15 pubmed publisher
    ..In this study the leaves of the anti-diabetic medicinal plant loquat (Eriobotrya japonica) were phytochemically investigated following hints from a pharmacophore-based virtual screening and a ..
  6. Tamaya K, Matsui T, Toshima A, Noguchi M, Ju Q, Miyata Y, et al. Suppression of blood glucose level by a new fermented tea obtained by tea-rolling processing of loquat (Eriobotrya japonica) and green tea leaves in disaccharide-loaded Sprague-Dawley rats. J Sci Food Agric. 2010;90:779-83 pubmed publisher
    ..The authors have successfully developed a new fermented tea product (LG tea) by co-fermentation of loquat (Eriobotrya japonica) leaf and summer-harvested green tea leaf...
  7. Shih C, Lin C, Wu J. Eriobotrya japonica improves hyperlipidemia and reverses insulin resistance in high-fat-fed mice. Phytother Res. 2010;24:1769-80 pubmed publisher
    The effect of Eriobotrya japonica Lindl. (loquat) on insulin resistance was examined in mice fed a high-fat (HF) diet...
  8. Kim M, Lee J, Seong A, Lee Y, Kim Y, Baek H, et al. Neuroprotective effects of Eriobotrya japonica against ?-amyloid-induced oxidative stress and memory impairment. Food Chem Toxicol. 2011;49:780-4 pubmed publisher
    ..b>Eriobotrya japonica has been used to treat several diseases in East Asia...
  9. Cha D, Eun J, Jeon H. Anti-inflammatory and antinociceptive properties of the leaves of Eriobotrya japonica. J Ethnopharmacol. 2011;134:305-12 pubmed publisher
    The leaves of Eriobotrya japonica Lindl. have been widely used as a traditional medicine for the treatment of many diseases including coughs and asthma...

More Information

Publications108 found, 100 shown here

  1. Banno N, Akihisa T, Tokuda H, Yasukawa K, Taguchi Y, Akazawa H, et al. Anti-inflammatory and antitumor-promoting effects of the triterpene acids from the leaves of Eriobotrya japonica. Biol Pharm Bull. 2005;28:1995-9 pubmed
    ..isolated and identified from the ethyl acetate-soluble fraction of the methanol extract of the leaves of loquat, Eriobotrya japonica LINDL. (Rosaceae)...
  2. Lu H, Chen J, Li W, Ren B, Wu J, Zhang H. Hypoglycemic effect of the total flavonoid fraction from folium Eriobotryae. Phytomedicine. 2009;16:967-71 pubmed publisher
    The antidiabetic effect of the total flavonoids fraction from leaves of Eriobotrya japonica (EJF) was evaluated through normal and streptozotocin-induced diabetic mice with graded oral doses of 150, 300, 450 mg/kg for 7 days or 14 days...
  3. Kim S, Shin T. Anti-inflammatory effect of leaves of Eriobotrya japonica correlating with attenuation of p38 MAPK, ERK, and NF-kappaB activation in mast cells. Toxicol In Vitro. 2009;23:1215-9 pubmed publisher
    ..In the present study, we investigate the effect an unspecified aqueous extract from leaves of Eriobotrya japonica Lindl...
  4. Lu H, Xi C, Chen J, Li W. [Determination of triterpenoid acids in leaves of Eriobotrya japonica collected at in different seasons]. Zhongguo Zhong Yao Za Zhi. 2009;34:2353-5 pubmed
    To find out the change regularity of triterpenoid acids content in leaves of Eriobotrya japonica. (Folium Eriobotryae) in different seasons.
  5. Choi Y, Seok Y, Yeo S, Jeong M, Lim S. Protective changes of inflammation-related gene expression by the leaves of Eriobotrya japonica in the LPS-stimulated human gingival fibroblast: microarray analysis. J Ethnopharmacol. 2011;135:636-45 pubmed publisher
    The leaf of Eriobotrya japonica (Ej) has been used for a long time as an oriental medicine to treat pulmonary inflammatory diseases...
  6. Fu X, Kong W, Peng G, Zhou J, Azam M, Xu C, et al. Plastid structure and carotenogenic gene expression in red- and white-fleshed loquat (Eriobotrya japonica) fruits. J Exp Bot. 2012;63:341-54 pubmed publisher
    Loquat (Eriobotrya japonica Lindl.) can be sorted into red- and white-fleshed cultivars...
  7. Wu L, Jiang X, Huang L, Chen S. Processing technology investigation of loquat (Eriobotrya japonica) leaf by ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry combined with chemometrics. PLoS ONE. 2013;8:e64178 pubmed publisher
    ..and multivariate statistical analysis were used to investigate the processing technology of Loquat (Eriobotrya japonica) leaf (pipaye, PPY)...
  8. Zhou C, Chen K, Sun C, Chen Q, Zhang W, Li X. Determination of oleanolic acid, ursolic acid and amygdalin in the flower of Eriobotrya japonica Lindl. by HPLC. Biomed Chromatogr. 2007;21:755-61 pubmed
    ..methods were developed for the determination of oleanolic acid (OA), ursolic acid (UA) and amygdalin in loquat (Eriobotrya japonica Lindl...
  9. Zhou C, Xu C, Sun C, Li X, Chen K. Carotenoids in white- and red-fleshed loquat fruits. J Agric Food Chem. 2007;55:7822-30 pubmed
    Fruits of 23 loquat ( Eriobotrya japonica Lindl.) cultivars, of which 11 were white-fleshed and 12 red-fleshed, were analyzed for color, carotenoid content, and vitamin A values...
  10. Matalka K, Ali D, Khawad A, Qa dan F. The differential effect of Eriobotrya japonica hydrophilic leaf extract on cytokines production and modulation. Cytokine. 2007;40:235-40 pubmed
    ..Of these agents, we found that Eriobotrya japonica hydrophilic leaf extract (EJHE) can induce and modulate cytokines in dose-dependent manner...
  11. Tanaka K, Nishizono S, Makino N, Tamaru S, Terai O, Ikeda I. Hypoglycemic activity of Eriobotrya japonica seeds in type 2 diabetic rats and mice. Biosci Biotechnol Biochem. 2008;72:686-93 pubmed
    The hypoglycemic effects of Eriobotrya japonica seeds were investigated in type 2 diabetic Otsuka Long-Evans Tokushima fatty (OLETF) rats and KK-A(y) mice...
  12. Hong Y, Lin S, Jiang Y, Ashraf M. Variation in contents of total phenolics and flavonoids and antioxidant activities in the leaves of 11 Eriobotrya species. Plant Foods Hum Nutr. 2008;63:200-4 pubmed publisher
    b>Eriobotrya plants are known to have significant amounts of phenolics and flavonoids, and exhibit a strong antioxidant activity...
  13. Qa dan F, Verspohl E, Nahrstedt A, Petereit F, Matalka K. Cinchonain Ib isolated from Eriobotrya japonica induces insulin secretion in vitro and in vivo. J Ethnopharmacol. 2009;124:224-7 pubmed publisher
    b>Eriobotrya japonica leaves had been used traditionally for the treatment of diabetes mellitus by immersing the dried leaves in a hot water drink...
  14. Ge J, Wang T, Zhao B, Lv X, Jin Y, Peng L, et al. Anti-inflammatory effect of triterpenoic Acids of Eriobotrya japonica (Thunb.) Lindl. Leaf on rat model of chronic bronchitis. Am J Chin Med. 2009;37:309-21 pubmed
    This study was designed to investigate the anti-inflammatory effect of Triterpenoic Acids from Eriobotrya japonica (Thunb.) Lindl. (TAL) on chronic bronchitis (CB) in rats...
  15. Cha D, Shin T, Eun J, Kim D, Jeon H. Anti-metastatic properties of the leaves of Eriobotrya japonica. Arch Pharm Res. 2011;34:425-36 pubmed publisher
    The leaves of Eriobotrya japonica Lindl. have been widely used as a traditional medicine for the treatment of many diseases including gastroenteric disorders, diabetes mellitus, chronic bronchitis and asthma...
  16. Yang Y, Huang Y, Huang C, Lv X, Liu L, Wang Y, et al. Antifibrosis effects of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf in a rat model of bleomycin-induced pulmonary fibrosis. J Pharm Pharmacol. 2012;64:1751-60 pubmed publisher
    ..The aim of this study was to investigate the prophylactic effect and some mechanisms of action of triterpene acids of loquat (TAL) on bleomycin A5-induced pulmonary fibrosis rats...
  17. Shih C, Ciou J, Lin C, Wu J, Ho H. Cell suspension culture of Eriobotrya japonica regulates the diabetic and hyperlipidemic signs of high-fat-fed mice. Molecules. 2013;18:2726-53 pubmed publisher
    ..and antihyperglycemic effects and mechanism in high-fat (HF)-fed mice of cell suspension culture of Eriobotrya japonica (TA), which contains a great number of pentacyclic terpenoids...
  18. Huang Y, Li J, Cao Q, Yu S, Lv X, Jin Y, et al. Anti-oxidative effect of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf in chronic bronchitis rats. Life Sci. 2006;78:2749-57 pubmed
    The study was to evaluate the effect of triterpene acids of Eriobotrya japonica (Thunb.) Lindl...
  19. Yokota J, Takuma D, Hamada A, Onogawa M, Yoshioka S, Kusunose M, et al. Scavenging of reactive oxygen species by Eriobotrya japonica seed extract. Biol Pharm Bull. 2006;29:467-71 pubmed
    We have clarified that Eriobotrya japonica seed extract has strong antioxidative activity, and is effective for the prevention and treatment of various diseases, such as hepatopathy and nephropathy...
  20. Shan L, Li X, Wang P, Cai C, Zhang B, Sun C, et al. Characterization of cDNAs associated with lignification and their expression profiles in loquat fruit with different lignin accumulation. Planta. 2008;227:1243-54 pubmed publisher
    The ripening fruit of two loquat (Eriobotrya japonica Lindl.) cultivars with different levels of lignin accumulation provide an intriguing example of lignification in flesh tissue...
  21. Sellés Marchart S, Luque I, Casado Vela J, Martínez Esteso M, Bru Martínez R. Proteomics of multigenic families from species underrepresented in databases: the case of loquat (Eriobotrya japonica Lindl.) polyphenol oxidases. J Proteome Res. 2008;7:4095-106 pubmed publisher
    ..gene origin of a protein belonging to a multigenic family, polyphenol oxidase, from an underrepresented species, Eriobotrya japonica. De novo sequencing was a key approach to obtain broad sequence coverage...
  22. Li E, Luo J, Kong L. Qualitative and quantitative determination of seven triterpene acids in Eriobotrya japonica Lindl. by high-performance liquid chromatography with photodiode array detection and mass spectrometry. Phytochem Anal. 2009;20:338-43 pubmed publisher
    The leaves of Eriobotrya japonica are used for the treatment of diabetes mellitus, chronic bronchitis, coughs and skin diseases...
  23. Zong W, Zhao G. Corosolic acid isolation from the leaves of Eriobotrta japonica showing the effects on carbohydrate metabolism and differentiation of 3T3-L1 adipocytes. Asia Pac J Clin Nutr. 2007;16 Suppl 1:346-52 pubmed
    ..01, vs control group). Corosolic acid promotes the 3H-glucose uptaking, suppresses the differentiation and downregulates the expression of PPAR-gamma and C/EBP-alpha mRNA in 3T3-L1 adipocytes. ..
  24. Gentile C, Reig C, Corona O, Todaro A, Mazzaglia A, Perrone A, et al. Pomological Traits, Sensory Profile and Nutraceutical Properties of Nine Cultivars of Loquat (Eriobotrya japonica Lindl.) Fruits Grown in Mediterranean Area. Plant Foods Hum Nutr. 2016;71:330-8 pubmed publisher
    ..Our data, besides helping to promote specific local cultivars, could serve to establish a database that will permit to improve the utilization of specific genetic resources in breeding programs. ..
  25. Jiang W, Huang S, Matsuda Y, Saito H, Uramaru N, Ho H, et al. Protective Effects of Tormentic Acid, a Major Component of Suspension Cultures of Eriobotrya japonica Cells, on Acetaminophen-Induced Hepatotoxicity in Mice. Molecules. 2017;22: pubmed publisher
    ..Therefore, TA may be a potential therapeutic candidate for the prevention of APAP-induced liver injury by inhibiting oxidative stress and inflammation. ..
  26. Sun G, Liu Y, Zhu J, Iguchi M, Yoshioka S, Miyamura M, et al. Immunomodulatory effect of Eriobotrya japonica seed extract on allergic dermatitis rats. J Nutr Sci Vitaminol (Tokyo). 2010;56:145-9 pubmed
    We examined the immunomodulatory effect of Eriobotrya japonica seed extract (ESE) on rat allergic dermatitis elicited by repeated dinitrofluorobenzene (DNFB) application on the ear...
  27. Ho H, Liang K, Lin W, Kitanaka S, Wu J. Regulation and improvement of triterpene formation in plant cultured cells of Eriobotrya japonica Lindl. J Biosci Bioeng. 2010;110:588-92 pubmed publisher
    Loquat (Eriobotrya japonica Lindl) is a traditional Chinese medicinal plant that contains triterpenes, which have been shown to exhibit pharmaceutical activities...
  28. Gong R, Lai J, Yang W, Liao M, Wang Z, Liang G. Analysis of alterations to the transcriptome of Loquat (Eriobotrya japonica Lindl.) under low temperature stress via de novo sequencing. Genet Mol Res. 2015;14:9423-36 pubmed publisher
    Loquat (Eriobotrya japonica Lindl.), which originates from the cooler hill regions of southwestern China, is a typical subtropical evergreen tree...
  29. Lu H, Chen J, Li W, Ren B, Wu J, Kang H, et al. Hypoglycemic and hypolipidemic effects of the total triterpene acid fraction from Folium Eriobotryae. J Ethnopharmacol. 2009;122:486-91 pubmed publisher
    ..agent to treat diabetes, the total triterpene acid (TTA) fraction extracted from Folium Eriobotryae [leaves of Eriobotrya japonica (Thunb.) Lindl...
  30. Miyata Y, Tamaru S, Tanaka T, Tamaya K, Matsui T, Nagata Y, et al. Theflavins and theasinensin A derived from fermented tea have antihyperglycemic and hypotriacylglycerolemic effects in KK-A(y) mice and Sprague-Dawley rats. J Agric Food Chem. 2013;61:9366-72 pubmed publisher
    ..These results indicate TFs and TSA induce antihyperglycemic responses in diabetic mice and are hypotriacylglycerolemic in rats by suppressing intestinal fat absorption. ..
  31. Hurtado Gonzales O, Aragon Caballero L, Flores Torres J, Man in t Veld W, Lamour K. Molecular comparison of natural hybrids of Phytophthora nicotianae and P. cactorum infecting loquat trees in Peru and Taiwan. Mycologia. 2009;101:496-502 pubmed
    ..The Peruvian hybrids appear to have persisted at least 3 y at three locations. Possible factors influencing the population structure of Phytophthora hybrids infecting loquat are discussed. ..
  32. Kim O, Nam D, Jun W, Lee J. Effects of Standardized Eriobotrya japonica Extract in LP-BM5 Murine Leukemia Viruses-Induced Murine Immunodeficiency Syndrome. Immunol Invest. 2016;45:148-60 pubmed publisher
    Folk medicine has long employed leaves from Eriobotrya japonica Lindl. (Rosaceae) (LEJ) as relieving many diseases including chronic bronchitis and high fever...
  33. Chen J, Li W, Wu J, Ren B, Zhang H. Euscaphic acid, a new hypoglycemic natural product from Folium Eriobotryae. Pharmazie. 2008;63:765-7 pubmed
    ..The research proved that euscaphic acid is one of the active hypoglycemic constituents in Folium Eriobotryae, but the details of the mechanism need to be investigated further. ..
  34. Zhao G, Yang Z, Guo Y. Cloning and expression of hydroxynitrile lyase gene from Eriobotrya japonica in Pichia pastoris. J Biosci Bioeng. 2011;112:321-5 pubmed publisher
    Hydroxynitrile lyase gene (hnl) from Eriobotrya japonica was successfully amplified using the method of SEFA PCR (Self-Formed Adaptor PCR). The complete sequence was 5...
  35. Nishioka Y, Yoshioka S, Kusunose M, Cui T, Hamada A, Ono M, et al. Effects of extract derived from Eriobotrya japonica on liver function improvement in rats. Biol Pharm Bull. 2002;25:1053-7 pubmed
    b>Eriobotrya japonica is considered a medicinal plant, and its leaves (Eriobotrya folia) have been used to treat skin diseases, as well as to relieve inflammation, pain, coughing, and sputa...
  36. Taskin M, Erdal S. Production of carotenoids by Rhodotorula glutinis MT-5 in submerged fermentation using the extract from waste loquat kernels as substrate. J Sci Food Agric. 2011;91:1440-5 pubmed publisher
    ..The practicability of the extracts as fermentation substrate was proven in carotenoid production. To the best of our knowledge, this is the first report on use of this waste material as a substrate in yeast fermentations. ..
  37. Matalka K, Abdulridha N, Badr M, Mansoor K, Qinna N, Qadan F. Eriobotrya japonica Water Extract Characterization: An Inducer of Interferon-Gamma Production Mainly by the JAK-STAT Pathway. Molecules. 2016;21: pubmed publisher
    b>Eriobotrya japonica (Thunb.) Lindl. (Loquat) (EJ) has been used as a medicinal plant to treat chronic bronchitis, coughs, phlegm, high fever and gastro-enteric disorders...
  38. Tan H, Sonam T, Shimizu K. The Potential of Triterpenoids from Loquat Leaves (Eriobotrya japonica) for Prevention and Treatment of Skin Disorder. Int J Mol Sci. 2017;18: pubmed publisher
    The leaves of loquat (Eriobotrya japonica) possess high medicinal value and have been used as traditional medicines. However, there are no evidence-based studies on the skin-care effects of E. japonica leaves...
  39. Jian T, Wu Y, Ding X, Lv H, Ma L, Zuo Y, et al. A novel sesquiterpene glycoside from Loquat leaf alleviates oleic acid-induced steatosis and oxidative stress in HepG2 cells. Biomed Pharmacother. 2018;97:1125-1130 pubmed publisher
    Loquat (Eriobotrya japonica) leaf has displayed beneficial effect on metabolic syndrome...
  40. Huang Y, Li J, Wang R, Wu Q, Li Y, Yu S, et al. Effect of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf on inflammatory cytokine and mediator induction from alveolar macrophages of chronic bronchitic rats. Inflamm Res. 2007;56:76-82 pubmed
    The study was to evaluate the effect of triterpene acids of Eriobotrya japonica (thunb.) lindl. leaf (TAL) on inflammatory cytokine and mediator expression in alveolar macrophages (AM) of chronic bronchitic (CB) rats...
  41. Onogawa M, Sun G, Takuma D, Hamada A, Yokota J, Yoshioka S, et al. Animal studies supporting the inhibition of mast cell activation by Eriobotrya japonica seed extract. J Pharm Pharmacol. 2009;61:237-41 pubmed publisher
    The potent antioxidant activity of Eriobotrya japonica seed extract (ESE) and its usefulness in the prevention and treatment of various disorders has been reported previously...
  42. Kawahara N, Satake M, Goda Y. A new acylated flavonol glycoside from the leaves of Eriobotrya japonica. Chem Pharm Bull (Tokyo). 2002;50:1619-20 pubmed
    A new acylated flavonol glycoside was isolated from the leaves of Eriobotrya japonica along with two known flavonol glycosides. Their structures were determined by extensive spectroscopic investigation.
  43. Cao S, Zheng Y, Tang S, Wang K. Improved control of anthracnose rot in loquat fruit by a combination treatment of Pichia membranifaciens with CaCl(2). Int J Food Microbiol. 2008;126:216-20 pubmed publisher
    ..membranifaciens for control of anthracnose rot caused by Colletotrichum acutatum in postharvest loquat fruit (Eriobotrya japonica L.) and the possible mechanisms involved were investigated. The results showed that treatment with P...
  44. Wang Y, Shahid M, Lin S, Chen C, Hu C. Footprints of domestication revealed by RAD-tag resequencing in loquat: SNP data reveals a non-significant domestication bottleneck and a single domestication event. BMC Genomics. 2017;18:354 pubmed publisher
    ..Loquat (Eriobotrya japonica Lindl...
  45. Song H, Wang X, Hu W, Yang X, Diao E, Shen T, et al. A cold-induced phytosulfokine peptide is related to the improvement of loquat fruit chilling tolerance. Food Chem. 2017;232:434-442 pubmed publisher
    ..Our results demonstrated that PSK1 improves chilling tolerance of loquat fruit by maintaining high energy status and cell integrity. Peptidomics analysis provides a promising tool to discover some key peptides. ..
  46. Eraso A, Albesa I. Eriobotrya japonica counteracts reactive oxygen species and nitric oxide stimulated by chloramphenicol. Am J Chin Med. 2007;35:875-85 pubmed
    ..The extract of fruits of Eriobotrya japonica markedly decreased ROS in leukocytes and erythrocytes, the oxidative stress caused by this antibiotic...
  47. Yokota J, Takuma D, Hamada A, Onogawa M, Yoshioka S, Kusunose M, et al. Gastroprotective activity of Eriobotrya japonica seed extract on experimentally induced gastric lesions in rats. J Nat Med. 2008;62:96-100 pubmed publisher
    The effect of Eriobotrya japonica seed extract (ESE) prepared with 70% ethanol on gastric mucosal injury was investigated. Six experimental models with different action mechanisms were used for the evaluation...
  48. Gumy C, Thurnbichler C, Aubry E, Balazs Z, Pfisterer P, Baumgartner L, et al. Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicines. Fitoterapia. 2009;80:200-5 pubmed publisher
    ..Leave extracts of Eriobotrya japonica preferentially inhibited 11beta-HSD1 over 11beta-HSD2...
  49. Yokota J, Kitaoka T, Jobu K, Takuma D, Hamada A, Onogawa M, et al. Eriobotrya japonica seed extract and deep sea water protect against indomethacin-induced gastric mucosal injury in rats. J Nat Med. 2011;65:9-17 pubmed publisher
    We have previously reported that Eriobotrya japonica seed extract (ESE) is effective for the treatment of various gastric mucosal injuries...
  50. Tan H, Furuta S, Nagata T, Ohnuki K, Akasaka T, Shirouchi B, et al. Inhibitory effects of the leaves of loquat (Eriobotrya japonica) on bone mineral density loss in ovariectomized mice and osteoclast differentiation. J Agric Food Chem. 2014;62:836-41 pubmed publisher
    The loquat, Eriobotrya japonica Lindl. (Rosaceae), is a small tree native to Japan and China that is widely cultivated for its succulent fruit. Its leaves are used as an ingredient of a tasty tea called "Biwa cha" in Japanese...
  51. Yang W, Wang Q, Xu K, Yin Y, Bao H, Li X, et al. Enhanced Corrosion Resistance of Carbon Steel in Hydrochloric Acid Solution by Eriobotrya Japonica Thunb. Leaf Extract: Electrochemical Study. Materials (Basel). 2017;10: pubmed publisher
    ..The mixed-type inhibitors extracted from Eriobotrya japonica Thunb...
  52. Cao S, Zheng Y, Wang K, Rui H, Tang S. Effect of 1-methylcyclopropene treatment on chilling injury, fatty acid and cell wall polysaccharide composition in loquat fruit. J Agric Food Chem. 2009;57:8439-43 pubmed publisher
  53. Huang Y, Li J, Meng X, Jiang G, Li H, Cao Q, et al. Effect of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf and MAPK signal transduction pathway on inducible nitric oxide synthase expression in alveolar macrophage of chronic bronchitis rats. Am J Chin Med. 2009;37:1099-111 pubmed
    The goal of this study was to investigate the possible therapy mechanism of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. Leaf (TAL) in alveolar macrophage (AM) of chronic bronchitis (CB) rats...
  54. Xu H, Chen J, Xie M. Effect of different light transmittance paper bags on fruit quality and antioxidant capacity in loquat. J Sci Food Agric. 2010;90:1783-8 pubmed publisher
    ..Two loquat cultivars, Baiyu and Ninghaibai (Eriobotrya japonica Lindl.), were used for materials...
  55. Cao S, Zheng Y. Effect of 1-methylcyclopropene on anthracnose rot caused by Colletotrichum acutatum and disease resistance in loquat fruit. J Sci Food Agric. 2010;90:2289-94 pubmed publisher
    Loquat (Eriobotrya japonica Lindl.) fruit are susceptible to fungal decay during postharvest storage at ambient temperature. The control of postharvest diseases of loquat is based primarily on the use of synthetic fungicides...
  56. Huang C, Lin Y, Kuo H, Chiou W, Lee M. Compounds isolated from Eriobotrya deflexa leaves protect against ultraviolet radiation B-induced photoaging in human fibroblasts. J Photochem Photobiol B. 2017;175:244-253 pubmed publisher
    ..b>Eriobotrya deflexa (Hemsl...
  57. Weiping S, Fashui H, Zhigang W. Effects of lanthanum element on the rooting of loquat plantlet in vitro. Biol Trace Elem Res. 2002;89:277-84 pubmed
    We investigated the rooting rate, the number of roots, and the state of growth of loquat (Eriobotrya japonica Lindi) plantlet in medium where La(NO3)3 (0.5-100.0 micromol/L) was added 20 d after transplanting...
  58. Hamada A, Yoshioka S, Takuma D, Yokota J, Cui T, Kusunose M, et al. The effect of Eriobotrya japonica seed extract on oxidative stress in adriamycin-induced nephropathy in rats. Biol Pharm Bull. 2004;27:1961-4 pubmed
    b>Eriobotrya japonica has been used as a medicinal plant for a long time, and its leaves are known to have many physiological actions such as anti-inflammatory, antitussive, and expectoran...
  59. Fu X, Li J, Zhou Y, Ying Y, Xie L, Niu X, et al. Determination of soluble solid content and acidity of loquats based on FT-NIR spectroscopy. J Zhejiang Univ Sci B. 2009;10:120-5 pubmed publisher
    ..382, 0.194, 0.388, and 0.361 for the above four loquats, respectively. The results indicate that NIR diffuse reflectance spectroscopy can be used to predict the SSC and acidity of loquat fruit. ..
  60. Hu J, Zhang H, Liu G, Tao Z, Zhong H. [Studies on extraction technology of total flavonoids from flower of Eriobotrya japonica]. Zhong Yao Cai. 2008;31:1724-7 pubmed
    To study the optimum extraction technology of total flavonoids from Flower of Eriobotrya japonica. To screen the best extraction technology by single-factor and orthogonal experiment according to the content of total flavonoids...
  61. Kaya G, Ozcan C, Yaman M. Flame atomic absorption spectrometric determination of Pb, Cd, and Cu in Pinus nigra L. and Eriobotrya japonica leaves used as biomonitors in environmental pollution. Bull Environ Contam Toxicol. 2010;84:191-6 pubmed publisher
    ..and Eriobotrya japonica as biomonitor. The concentrations up to 3,056 mg Pb kg(-1) in the needles of Pinus nigra L...
  62. Yoshioka S, Hamada A, Jobu K, Yokota J, Onogawa M, Kyotani S, et al. Effects of Eriobotrya japonica seed extract on oxidative stress in rats with non-alcoholic steatohepatitis. J Pharm Pharmacol. 2010;62:241-6 pubmed publisher
    ..We previously reported that an Eriobotrya japonica seed extract, extracted in 70% ethanol, exhibited antioxidant actions in vitro and in vivo...
  63. He J, Liu Q, Bai Z, Huang R, Wang Z. [An optimized method for extracting corosolic acid from loquat leaves]. Nan Fang Yi Ke Da Xue Xue Bao. 2010;30:2533-5 pubmed
    ..The optimal extraction method, which is convenient and cost-effective, is established for extracting corosolic acid from loquat leaves for medical use. ..
  64. Hadjipieri M, Georgiadou E, MarIn A, Díaz Mula H, Goulas V, Fotopoulos V, et al. Metabolic and transcriptional elucidation of the carotenoid biosynthesis pathway in peel and flesh tissue of loquat fruit during on-tree development. BMC Plant Biol. 2017;17:102 pubmed publisher
    ..A link between gene up- or down-regulation during the developmental stages of the loquat fruit, and how their expression affects carotenoid content per tissue (peel or flesh) was established. ..
  65. Elloumi N, Zouari M, Mezghani I, Ben Abdallah F, Woodward S, Kallel M. Adaptive biochemical and physiological responses of Eriobotrya japonica to fluoride air pollution. Ecotoxicology. 2017;: pubmed publisher
    The biochemical and physiological effects of fluoride were investigated in loquat trees (Eriobotrya japonica) grown in the vicinity of a phosphate fertilizer plant in Tunisia...
  66. Soriano J, Romero C, Vilanova S, Llácer G, Badenes M. Genetic diversity of loquat germplasm (Eriobotrya japonica (Thunb) Lindl) assessed by SSR markers. Genome. 2005;48:108-14 pubmed
    Genetic relationships among 40 loquat (Eriobotrya japonica (Thunb) Lindl) accessions that originated from different countries and that are part of the germplasm collection of the Instituto Valenciano de Investigaciones Agrarias (IVIA) (..
  67. Ge H, Zhang J, Zhang Y, Li X, Yin X, Grierson D, et al. EjNAC3 transcriptionally regulates chilling-induced lignification of loquat fruit via physical interaction with an atypical CAD-like gene. J Exp Bot. 2017;68:5129-5136 pubmed publisher
    Lignin is an important component of many plant secondary cell walls. In the fruit of loquat (Eriobotrya japonica), lignification of cell walls in the fleshy tissue occurs when fruit are subjected to low-temperature storage, which is ..
  68. Bru Martínez R, Martínez Márquez A, Morante Carriel J, Sellés Marchart S, Martínez Esteso M, Pineda Lucas J, et al. Targeted Quantification of Isoforms of a Thylakoid-Bound Protein: MRM Method Development. Methods Mol Biol. 2018;1696:147-162 pubmed publisher
    ..the issues to take into consideration in order to develop a MRM method to detect and quantify isoforms of the thylakoid-bound protein polyphenol oxidase from the non-model and database underrepresented species Eriobotrya japonica Lindl.
  69. Fashui H, Weiping S, Zhigang W, Mingliang Y, Jia Y, Jiajia L, et al. Effect of La(III) on the growth and aging of root of loquat plantlet in vitro. Biol Trace Elem Res. 2005;104:185-91 pubmed
    ..There are important theory meaning and practical value in applying LaCl3 in the rooting medium to raise the rate of rooting and transplant for wood plant...
  70. Ordax M, Marco Noales E, Lopez M, Biosca E. Survival strategy of Erwinia amylovora against copper: induction of the viable-but-nonculturable state. Appl Environ Microbiol. 2006;72:3482-8 pubmed
    ..These results have shown, for the first time, the induction of the VBNC state in E. amylovora as a survival strategy against copper...
  71. Lu X, Liu Y. [Analysis of volatile oil in pre and post processed pieces of Eriobotrya japonica by GC-MS]. Zhong Yao Cai. 2008;31:1625-6 pubmed
    To analyze the chemical components of the volatile oil in processed pieces of Eriobotrya japonica by GC-MS.
  72. Souza Filho M, Raga A, Azevedo Filho J, Strikis P, Guimaraes J, Zucchi R. Diversity and seasonality of fruit flies (Diptera: Tephritidae and Lonchaeidae) and their parasitoids (Hymenoptera: Braconidae and Figitidae) in orchards of guava, loquat and peach. Braz J Biol. 2009;69:31-40 pubmed
    ..Ceratitis capitata showed a seasonal behavior with population density peaking at the second semester of each year. Anastrepha and Neosilba species remained in the orchards throughout both years...
  73. Tanaka T, Miyata Y, Tamaya K, Kusano R, Matsuo Y, Tamaru S, et al. Increase of theaflavin gallates and thearubigins by acceleration of catechin oxidation in a new fermented tea product obtained by the tea-rolling processing of loquat ( Eriobotrya japonica ) and green tea leaves. J Agric Food Chem. 2009;57:5816-22 pubmed publisher
    ..harvested in the summer, we found that kneading tea leaves ( Camellia sinensis ) with fresh loquat leaves ( Eriobotrya japonica ) accelerated the enzymatic oxidation of tea catechins...
  74. Chen Q, Zhang Y, Zhang W, Chen Z. Identification and quantification of oleanolic acid and ursolic acid in Chinese herbs by liquid chromatography-ion trap mass spectrometry. Biomed Chromatogr. 2011;25:1381-8 pubmed publisher
    ..78 to 2.15%, and the accuracy was 96.5-108.2% for UA and OA. The mean recovery of UA and OA was 97.1-106.2% with RSD less than 1.86%. An LC-IT-MS method was successfully applied to determine the UA and OA in nine Chinese herbs...
  75. Saliba W, Goldstein L, Habib G, Elias M. Toxic myopathy induced by the ingestion of loquat leaf extract. Ann Rheum Dis. 2004;63:1355-6 pubmed
  76. Huang S, Liu S, Zong M, Xu R. Synthesis of (R)-2-trimethylsilyl-2-hydroxyl-ethylcyanide catalyzed with (R)-oxynitrilase from loquat seed meal. Biotechnol Lett. 2005;27:79-82 pubmed
    ..The substrate conversion and the product enantiomeric excess were 95% and 98% under the optimized conditions. Acetyltrimethylsilane was a better substrate of the enzyme than its carbon counterpart...
  77. Taniguchi S. [Effective productions of plant secondary metabolites having antitumor activity by plant cell and tissue cultures]. Yakugaku Zasshi. 2005;125:499-507 pubmed
    ..Cultured cells of Eriobotrya japonica producing ursane- and oleanane-type triterpenes with antitumor activities were also established.
  78. Sellés Marchart S, Casado Vela J, Bru Martínez R. Effect of detergents, trypsin and unsaturated fatty acids on latent loquat fruit polyphenol oxidase: basis for the enzyme's activity regulation. Arch Biochem Biophys. 2007;464:295-305 pubmed
    ..Down-regulation of PPO activity by anionic amphiphiles is discussed based on both, the pH profile shift induced upon anionic amphiphile binding and the PPO interaction with negatively charged membranes...
  79. Li W, Wu J, Ren B, Chen J, Lu C. Pharmacological studies on anti-hyperglycemic effect of folium eriobotryae. Am J Chin Med. 2007;35:705-11 pubmed
    Folium eriobotryae, dried leaves of Eriobotrya japonica (Thunb.) Lindl. is a traditional Chinese medicine with rich resources in China...
  80. Sun G, Zhang Y, Takuma D, Onogawa M, Yokota J, Hamada A, et al. Effect of orally administered Eriobotrya japonica seed extract on allergic contact dermatitis in rats. J Pharm Pharmacol. 2007;59:1405-12 pubmed
    The anti-allergic activity of Eriobotrya japonica seeds extract (ESE) was investigated...
  81. Zhao P, Li L, Yang X, Jiao H. [Preparation and quality evaluation of fufangxiaoyepipa dispersible tablets]. Zhong Yao Cai. 2010;33:988-90 pubmed
    ..To study the preparation of fufangxiaoyepipa dispersible tablets and evaluate its quality...
  82. Weber M, Garner M. Cyanide toxicosis in Asian small-clawed otters (Amblonyx cinereus) secondary to ingestion of loquat (Eriobotrya japonica). J Zoo Wildl Med. 2002;33:145-6 pubmed
    ..The animals' exhibit contained opened, uneaten loquat (Eriobotrya japonica) fruit with the seeds removed and large quantities of undigested loquat seed material in the feces of ..
  83. Doran I, Kaya Z, Caglar S. Effects of farmyard manure and chemical fertilizers on the nutritional status of the loquat trees. J Environ Biol. 2003;24:315-9 pubmed
    ..It was concluded that the loquat trees grown in sandy soils could fulfill their principal nutrient requirements for growth and commercial yield with application of farmyard manure...
  84. Hueso J, Perez M, Alonso F, Cuevas J. Harvest prediction in 'Algerie' loquat. Int J Biometeorol. 2007;51:449-55 pubmed
    ..However, GDD reflects the developmental rate in water-stressed trees better than calendar days. Trees under deficit irrigation during flower development required more time and more heat to ripen their fruits...
  85. Wang M, Xu R, He J. [Study on the use of ultrasound technique in extraction of polysaccharides from Loquat leaf]. Zhong Yao Cai. 2006;29:1230-3 pubmed
    ..In contrast to conventional extraction method, the ultrasound technique could be a better method for extracting the polysaccharides from Loquat leaf with a higher yield and shorter time...
  86. Alshaker H, Qinna N, Qadan F, Bustami M, Matalka K. Eriobotrya japonica hydrophilic extract modulates cytokines in normal tissues, in the tumor of Meth-A-fibrosarcoma bearing mice, and enhances their survival time. BMC Complement Altern Med. 2011;11:9 pubmed publisher
    ..Previously, we have shown that the Eriobotrya japonica hydrophilic extract (EJHE) induces proinflammatory cytokines in vitro and in vivo.
  87. Shii T, Tanaka T, Watarumi S, Matsuo Y, Miyata Y, Tamaya K, et al. Polyphenol composition of a functional fermented tea obtained by tea-rolling processing of green tea and loquat leaves. J Agric Food Chem. 2011;59:7253-60 pubmed publisher
    ..Isolation of these new and known compounds confirms that reactions previously demonstrated by in vitro model experiments actually occur when fresh tea leaves are mechanically distorted and bruised during the production process...
  88. Fang Q, Chen Y, Huang S. Generalist passerine pollination of a winter-flowering fruit tree in central China. Ann Bot. 2012;109:379-84 pubmed publisher
    ..Birds can be alternative pollinators for these plants, but experimental evidence for the pollination role of birds in winter-flowering plants is scarce...
  89. Lewis V, Leighton S, Tabuchi R, Baldwin J, Haverty M. Influence of environmental factors on activity patterns of Incisitermes minor (Isoptera: Kalotermitidae) in naturally infested logs. J Econ Entomol. 2013;106:338-46 pubmed
    Acoustic emission (AE) activity patterns were measured from seven loquat [Eriobotrya japonica (Thunb.) Lindl...
  90. Hou W, Lin R, Cheng K, Hung Y, Cho C, Chen C, et al. Free radical-scavenging activity of Taiwanese native plants. Phytomedicine. 2003;10:170-5 pubmed
    ..buerferianum var. formosanum, C. japonica var. morii, C. stenophylla var. stenophylloides, Eriobotrya deflex, and M. zuihoensis showed high activity. The results indicate the 70% aqueous acetone extracts of A...
  91. Lee M, Son Y, Han Y. Tissue factor inhibitory sesquiterpene glycoside from Eriobotrya japonica. Arch Pharm Res. 2004;27:619-23 pubmed
    ..isolate TF inhibitors, by means of a bioassay-directed chromatographic separation technique, from the leaves of Eriobotrya japonica Lindley (Rosaceae), a known sesquiterpene glycoside (2) and ferulic acid (3) were isolated as ..
  92. Molinu M, D hallewin G, Dore A, Serusi A, Venditti T, Agabbio M. Carbonic acid salts at 25 or 45 degrees C to control loquat decay under shelf life conditions. Commun Agric Appl Biol Sci. 2005;70:365-70 pubmed
    ..Weight losses were related to treatment temperature and salts concentrations whereas, no differences were detected in the chemical parameters compared to the control...