morus

Summary

Summary: A plant genus of the family MORACEAE that is widely planted for shade.

Top Publications

  1. Mudra M, Ercan Fang N, Zhong L, Furne J, Levitt M. Influence of mulberry leaf extract on the blood glucose and breath hydrogen response to ingestion of 75 g sucrose by type 2 diabetic and control subjects. Diabetes Care. 2007;30:1272-4 pubmed
  2. Hassimotto N, Genovese M, Lajolo F. Absorption and metabolism of cyanidin-3-glucoside and cyanidin-3-rutinoside extracted from wild mulberry (Morus nigra L.) in rats. Nutr Res. 2008;28:198-207 pubmed publisher
    ..As found by the everted sac model, anthocyanins were transported across the enterocyte by the sodium-dependent glucose transporter. ..
  3. Bharani S, Asad M, Dhamanigi S, Chandrakala G. Immunomodulatory activity of methanolic extract of Morus alba Linn. (mulberry) leaves. Pak J Pharm Sci. 2010;23:63-8 pubmed
    The leaves of Morus alba Linn. (Family: Moraceae) commonly known as mulberry are mainly used as food for the silkworms and they are sometimes eaten as vegetable or used as cattle fodder in different parts of the world...
  4. Kimura T, Nakagawa K, Kubota H, Kojima Y, Goto Y, Yamagishi K, et al. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem. 2007;55:5869-74 pubmed
    ..After optimization of the harvesting and drying processes for young mulberry leaves (Morus alba L. var. Shin ichinose), DNJ-enriched powder (1.5%) was produced...
  5. Han W, Liu L, Zhang X, Ye W, Pan Y, Yao X. [Chemical constituents from leaves of Morus multicaulis]. Zhongguo Zhong Yao Za Zhi. 2007;32:695-8 pubmed
    To study the chemical constituents from the leaves of Morus multicaulis. The compounds were isolated by ion exchange resin, silica gel and Sephadex LH -20 column chromatographies...
  6. Jeong J, Jang S, Kim T, Kwon C, Kim Y. Mulberry fruit (Moris fructus) extracts induce human glioma cell death in vitro through ROS-dependent mitochondrial pathway and inhibits glioma tumor growth in vivo. Nutr Cancer. 2010;62:402-12 pubmed publisher
    ..These findings suggest that MF extracts result in human glioma cell death in vitro through ROS-dependent mitochondrial pathway and glioma tumor growth in vivo via reduction of tumor cell proliferation and induction of apoptosis. ..
  7. Naowaboot J, Pannangpetch P, Kukongviriyapan V, Prawan A, Kukongviriyapan U, Itharat A. Mulberry leaf extract stimulates glucose uptake and GLUT4 translocation in rat adipocytes. Am J Chin Med. 2012;40:163-75 pubmed
    Mulberry (Morus alba L.) leaf tea is promoted for its health benefits and the control of diabetes in Asian nations...
  8. Aramwit P, Petcharat K, Supasyndh O. Efficacy of mulberry leaf tablets in patients with mild dyslipidemia. Phytother Res. 2011;25:365-9 pubmed publisher
    ..7%) or constipation and bloating (4.3%), mulberry leaf tablet therapy is still capable and safe in reducing cholesterol levels and enhancing HDL in patients with mild dyslipidemia. ..
  9. Kitajima S, Taira T, Oda K, Yamato K, Inukai Y, Hori Y. Comparative study of gene expression and major proteins' function of laticifers in lignified and unlignified organs of mulberry. Planta. 2012;235:589-601 pubmed publisher
    ..compared protein accumulation and transcriptomes among laticifers of lignified and unlignified organs of mulberry (Morus alba), which has a non-articulated, branched type of laticifer...

More Information

Publications87

  1. Datta S. Effects of Cina on root-knot disease of mulberry. Homeopathy. 2006;95:98-102 pubmed
    ..from the flowering meristems of Artemisia nilagirica (Clarke) Pamp, were applied by foliar spray on mulberry (Morus alba L.) infected with M. incognita juveniles (J2)...
  2. Naowaboot J, Pannangpetch P, Kukongviriyapan V, Kukongviriyapan U, Nakmareong S, Itharat A. Mulberry leaf extract restores arterial pressure in streptozotocin-induced chronic diabetic rats. Nutr Res. 2009;29:602-8 pubmed publisher
    ..b>Morus alba (MA) leaf extract is promoted for good health especially in diabetic patients...
  3. Katsube T, Yamasaki M, Shiwaku K, Ishijima T, Matsumoto I, Abe K, et al. Effect of flavonol glycoside in mulberry (Morus alba L.) leaf on glucose metabolism and oxidative stress in liver in diet-induced obese mice. J Sci Food Agric. 2010;90:2386-92 pubmed publisher
    ..Dietary consumption of Q3MG, the quantitatively major flavonol glycoside in mulberry leaves, improved hyperglycemia in obese mice and reduced oxidative stress in the liver. ..
  4. Ji X, Lu G, Gai Y, Zheng C, Mu Z. Biological control against bacterial wilt and colonization of mulberry by an endophytic Bacillus subtilis strain. FEMS Microbiol Ecol. 2008;65:565-73 pubmed publisher
    Forty-five bacterial isolates were collected from surface-sterilized leaves of mulberry (Morus alba L.)...
  5. Rollinger J, Spitaler R, Menz M, Marschall K, Zelger R, Ellmerer E, et al. Venturia inaequalis-inhibiting Diels-Alder adducts from Morus root bark. J Agric Food Chem. 2006;54:8432-6 pubmed
    ..From a screening of plant extracts, the methanol extract of Morus root bark revealed distinct V. inaequalis inhibiting qualities, which were subjected to a bioguided fractionation...
  6. Zhang M, Chen M, Zhang H, Sun S, Xia B, Wu F. In vivo hypoglycemic effects of phenolics from the root bark of Morus alba. Fitoterapia. 2009;80:475-7 pubmed publisher
    Moracin M (1), Steppogenin-4'-O-beta-D-glucosiade (2), Mullberroside A (3) were isolated from the root bark of Morus alba L. and identified by spectral evidence...
  7. He N, Zhang C, Qi X, Zhao S, Tao Y, Yang G, et al. Draft genome sequence of the mulberry tree Morus notabilis. Nat Commun. 2013;4:2445 pubmed publisher
    ..Complementing the silkworm genome sequence, here we describe the genome of a mulberry species Morus notabilis. In the 330-Mb genome assembly, we identify 128 Mb of repetitive sequences and 29,338 genes, 60...
  8. Konno K, Ono H, Nakamura M, Tateishi K, Hirayama C, Tamura Y, et al. Mulberry latex rich in antidiabetic sugar-mimic alkaloids forces dieting on caterpillars. Proc Natl Acad Sci U S A. 2006;103:1337-41 pubmed
    Since ancient times, mulberry leaves (Morus spp.) have been used to rear the silkworm Bombyx mori...
  9. Huang H, Shih Y, Chang Y, Hung C, Wang C. Chemoinhibitory effect of mulberry anthocyanins on melanoma metastasis involved in the Ras/PI3K pathway. J Agric Food Chem. 2008;56:9286-93 pubmed publisher
    ..Taken together, the findings proved the inhibitory effect of MACs on the growth and metastasis of B16-F1 cells. These results indicated that MACs might be offered for future application as an antimetastatic agent. ..
  10. Chang L, Juang L, Wang B, Wang M, Tai H, Hung W, et al. Antioxidant and antityrosinase activity of mulberry (Morus alba L.) twigs and root bark. Food Chem Toxicol. 2011;49:785-90 pubmed publisher
    ..Acting as an antioxidant and a tyrosinase inhibitor, these bioactive constituents could contribute to the protective effects of EEMT. Overall, the results showed that EEMT might serve as a natural antioxidant and tyrosinase inhibitor. ..
  11. Kim G, Kwon Y, Jang H. Mulberry leaf extract reduces postprandial hyperglycemia with few side effects by inhibiting ?-glucosidase in normal rats. J Med Food. 2011;14:712-7 pubmed publisher
    Mulberry (Morus alba L.) leaf extract (MLE) was investigated as a potent plant-derived ?-glucosidase inhibitor with low ?-amylase inhibitory activity...
  12. Nam S, Jang H, Shibamoto T. Antioxidant activities of extracts from teas prepared from medicinal plants, Morus alba L., Camellia sinensis L., and Cudrania tricuspidata , and their volatile components. J Agric Food Chem. 2012;60:9097-105 pubmed publisher
    The antioxidant activity of essences of teas prepared from mulberry ( Morus alba L.), Camellia sinensis L., and Cudrania tricuspidata (Carr.) Burea plant was examined using two antioxidant assays...
  13. Kang T, Oh H, Jung S, Ryu J, Park M, Park Y, et al. Enhancement of neuroprotection of mulberry leaves (Morus alba L.) prepared by the anaerobic treatment against ischemic damage. Biol Pharm Bull. 2006;29:270-4 pubmed
    ..Overall, these results suggest that the anaerobic treatment of ML makes GAML enhance the neuroprotection effect against in vivo cerebral ischemia such as in vitro. ..
  14. Shih P, Chan Y, Liao J, Wang M, Yen G. Antioxidant and cognitive promotion effects of anthocyanin-rich mulberry (Morus atropurpurea L.) on senescence-accelerated mice and prevention of Alzheimer's disease. J Nutr Biochem. 2010;21:598-605 pubmed publisher
    ..Overall, supplementation of ME might be advantageous to the induction of an antioxidant defense system and for the improvement of memory deterioration in ageing animals. ..
  15. Wu T, Qi X, Liu Y, Guo J, Zhu R, Chen W, et al. Dietary supplementation with purified mulberry (Morus australis Poir) anthocyanins suppresses body weight gain in high-fat diet fed C57BL/6 mice. Food Chem. 2013;141:482-7 pubmed publisher
    ..cyanidin-3-glucoside, cyanidin-3-rutinoside and pelargonidin-3-glucoside) purified from Chinese mulberry (Morus australis Poir) were evaluated for suppressing body weight gain of the male C57BL/6 mice fed with high-fat diet (..
  16. Hunyadi A, Martins A, Hsieh T, Seres A, Zupko I. Chlorogenic acid and rutin play a major role in the in vivo anti-diabetic activity of Morus alba leaf extract on type II diabetic rats. PLoS ONE. 2012;7:e50619 pubmed publisher
    The leaves of the white mulberry tree (Morus alba L.) are used worldwide in traditional medicine as anti-diabetics. Various constituents of mulberry leaves, such as iminosugars (i.e...
  17. Oh K, Ryu S, Lee S, Seo H, Oh B, Kim Y, et al. Melanin-concentrating hormone-1 receptor antagonism and anti-obesity effects of ethanolic extract from Morus alba leaves in diet-induced obese mice. J Ethnopharmacol. 2009;122:216-20 pubmed
    In Korea, Morus alba leaves have been traditionally administered as natural therapeutic agent for the alleviating dropsy and diabetes...
  18. Salinas Chavira J, Castillo Martínez O, Ramirez Bribiesca J, Mellado M. Effect of increasing levels of white mulberry leaves (Morus alba) on ruminal dry matter degradability in lambs. Trop Anim Health Prod. 2011;43:995-9 pubmed publisher
    ..of lambs offered a basal soybean meal and sorghum grain diet with three levels of white mulberry (WM) leaves (Morus alba)...
  19. Wang Y, Xiang L, Wang C, Tang C, He X. Antidiabetic and antioxidant effects and phytochemicals of mulberry fruit (Morus alba L.) polyphenol enhanced extract. PLoS ONE. 2013;8:e71144 pubmed publisher
    The antidiabetic and antioxidant activities of the ethyl acetate-soluble extract (MFE) of mulberry fruit (Morus alba L.) were investigated...
  20. Doi H. Response of the Morus bombycis growing season to temperature and its latitudinal pattern in Japan. Int J Biometeorol. 2012;56:895-902 pubmed publisher
    ..This study analyzed the datasets of leaf budburst and fall phenology in Morus bombycis (Urticales), which were observed by the agency of the Japan Meteorological Agency (JMA) from 1953 to 2005 ..
  21. Yang X, Yang L, Zheng H. Hypolipidemic and antioxidant effects of mulberry (Morus alba L.) fruit in hyperlipidaemia rats. Food Chem Toxicol. 2010;48:2374-9 pubmed publisher
    The phytochemical constituents of a freeze-dried powder of mulberry (Morus alba L.) fruit (MFP) were determined...
  22. Song W, Wang H, Bucheli P, Zhang P, Wei D, Lu Y. Phytochemical profiles of different mulberry (Morus sp.) species from China. J Agric Food Chem. 2009;57:9133-40 pubmed publisher
    ..Among the varieties tested, Da 10 (Morus atropurpurea Roxb.) was the most valuable cultivar considering its high content of functional components...
  23. Shibata Y, Kume N, Arai H, Hayashida K, Inui Hayashida A, Minami M, et al. Mulberry leaf aqueous fractions inhibit TNF-alpha-induced nuclear factor kappaB (NF-kappaB) activation and lectin-like oxidized LDL receptor-1 (LOX-1) expression in vascular endothelial cells. Atherosclerosis. 2007;193:20-7 pubmed
    Mulberry (Morus Alba L., family Moraceae) leaf extracts have various biological effects including inhibition of oxidative modification of low-density lipoprotein (LDL), which is the major cause of atherosclerosis...
  24. Hong Y, Kim M, Yoon M. The anti-angiogenic herbal extracts Ob-X from Morus alba, Melissa officinalis, and Artemisia capillaris suppresses adipogenesis in 3T3-L1 adipocytes. Pharm Biol. 2011;49:775-83 pubmed publisher
    ..Labiatae), Morus alba L. (Moraceae), and Artemisia capillaris Thunb...
  25. Lal S, Gulyani V, Khurana P. Overexpression of HVA1 gene from barley generates tolerance to salinity and water stress in transgenic mulberry (Morus indica). Transgenic Res. 2008;17:651-63 pubmed
    ..Thus hva1 appears to confer a broad spectrum of tolerance under abiotic stress in mulberry...
  26. Pan G, Lou C. Isolation of an 1-aminocyclopropane-1-carboxylate oxidase gene from mulberry (Morus alba L.) and analysis of the function of this gene in plant development and stresses response. J Plant Physiol. 2008;165:1204-13 pubmed
    Mulberry (Morus alba) is an important crop tree involved in sericulture and pharmaceuticals...
  27. Liu L, Chou F, Chen Y, Chyau C, Ho H, Wang C. Effects of mulberry (Morus alba L.) extracts on lipid homeostasis in vitro and in vivo. J Agric Food Chem. 2009;57:7605-11 pubmed publisher
    ..Therefore, MWEs could be used as a natural agent against hyperlipidemia...
  28. Devi V, Urooj A. Hypoglycemic potential of Morus indica. L and Costus igneus. Nak.--a preliminary study. Indian J Exp Biol. 2008;46:614-6 pubmed
    ..The preliminary results suggest that both the plants possess potent hypoglycemic activity...
  29. Tanaka K, Uda Y, Ono Y, Nakagawa T, Suwa M, Yamaoka R, et al. Highly selective tuning of a silkworm olfactory receptor to a key mulberry leaf volatile. Curr Biol. 2009;19:881-90 pubmed publisher
    ..Here, we aimed to identify natural chemoattractants and their corresponding olfactory receptors (Ors) involved in silkworm behavior to mulberry leaves...
  30. Kim S, Chang B, Jo Y, Lee S, Han S, Hwang B, et al. Macrophage activating activity of pyrrole alkaloids from Morus alba fruits. J Ethnopharmacol. 2013;145:393-6 pubmed publisher
    The fruits of Morus alba have been traditionally used as a tonic to enhance immune responses.
  31. Chen J, Li X. Hypolipidemic effect of flavonoids from mulberry leaves in triton WR-1339 induced hyperlipidemic mice. Asia Pac J Clin Nutr. 2007;16 Suppl 1:290-4 pubmed
    ..The total flavonoids have been isolated from mulberry (Morus alba L.) leaves and purified by macroporous resins. After that, the content of MTF is 581...
  32. Singh V, Patel A, Moir A, Jagannadham M. Indicain, a dimeric serine protease from Morus indica cv. K2. Phytochemistry. 2008;69:2110-9 pubmed publisher
    A high molecular mass serine protease has been purified to homogeneity from the latex of Morus indica cv...
  33. Ji X, Gai Y, Zheng C, Mu Z. Comparative proteomic analysis provides new insights into mulberry dwarf responses in mulberry (Morus alba L.). Proteomics. 2009;9:5328-39 pubmed publisher
    ..To better understand the pathogen-stress response of mulberry (Morus alba L...
  34. Dat N, Jin X, Lee K, Hong Y, Kim Y, Lee J. Hypoxia-inducible factor-1 inhibitory benzofurans and chalcone-derived diels-alder adducts from Morus species. J Nat Prod. 2009;72:39-43 pubmed publisher
    ..Bioassay-guided fractionation of the chloroform-soluble extracts of Morus species using a hypoxia response element (HRE)-dependent reporter assay led to identification of six benzofurans (..
  35. Tanabe K, Nakamura S, Omagari K, Oku T. Repeated ingestion of the leaf extract from Morus alba reduces insulin resistance in KK-Ay mice. Nutr Res. 2011;31:848-54 pubmed publisher
    ..of this study was to test the hypothesis that repeated ingestion of diet containing the leaf extract from a Morus alba (LEM) maintains the postprandial hypoglycemic response and suppresses the progression of insulin resistance ..
  36. Yang Y, Gong T, Liu C, Chen R. Four new 2-arylbenzofuran derivatives from leaves of Morus alba L. Chem Pharm Bull (Tokyo). 2010;58:257-60 pubmed
    ..V-Y (1-4), together with two known compounds, moracin N (5) and moracin P (6), were isolated from the leaves of Morus alba L. Their structures were elucidated by spectroscopic analysis...
  37. Kim H, Ju M, Shim J, Kim M, Lee S, Huh Y, et al. Mulberry fruit protects dopaminergic neurons in toxin-induced Parkinson's disease models. Br J Nutr. 2010;104:8-16 pubmed publisher
    ..Mulberry fruit from Morus alba L. (Moraceae) is commonly eaten, and has long been used in traditional oriental medicine...
  38. Padilha M, Vilela F, Rocha C, Dias M, Soncini R, Dos Santos M, et al. Antiinflammatory properties of Morus nigra leaves. Phytother Res. 2010;24:1496-500 pubmed publisher
    The aim of the present study was to investigate antiinflammatory activity of the methylene chloride extract of Morus nigra in animal models. Carrageenan-induced paw edema as well as fibrovascular tissue growth induced by s.c...
  39. Guo C, Li R, Zheng N, Xu L, Liang T, He Q. Anti-diabetic effect of ramulus mori polysaccharides, isolated from Morus alba L., on STZ-diabetic mice through blocking inflammatory response and attenuating oxidative stress. Int Immunopharmacol. 2013;16:93-9 pubmed publisher
  40. Ma X, Iwanaka N, Masuda S, Karaike K, Egawa T, Hamada T, et al. Morus alba leaf extract stimulates 5'-AMP-activated protein kinase in isolated rat skeletal muscle. J Ethnopharmacol. 2009;122:54-9 pubmed publisher
    b>Morus alba (mulberry) leaf is a natural therapeutic agent that has been shown to have an antidiabetic effect...
  41. Kitajima S, Kamei K, Taketani S, Yamaguchi M, Kawai F, Komatsu A, et al. Two chitinase-like proteins abundantly accumulated in latex of mulberry show insecticidal activity. BMC Biochem. 2010;11:6 pubmed publisher
    ..Proteins abundantly accumulated in latex might therefore be involved in the defense system...
  42. Amézqueta S, Galán E, Fuguet E, Carrascal M, Abian J, Torres J. Determination of D-fagomine in buckwheat and mulberry by cation exchange HPLC/ESI-Q-MS. Anal Bioanal Chem. 2012;402:1953-60 pubmed publisher
    ..0-43 mg kg(-1)), which has not previously been reported in this source. The procedure is also applied to mulberry (Morus alba) leaves, which contain D-fagomine and 3-epi-fagomine as minor components...
  43. Naowaboot J, Pannangpetch P, Kukongviriyapan V, Kongyingyoes B, Kukongviriyapan U. Antihyperglycemic, antioxidant and antiglycation activities of mulberry leaf extract in streptozotocin-induced chronic diabetic rats. Plant Foods Hum Nutr. 2009;64:116-21 pubmed publisher
    In Thailand, beverages containing mulberry leaf (Morus alba L.) are believed to promote good health, especially in people with diabetes...
  44. Wang W, Zu Y, Fu Y, Efferth T. In vitro antioxidant and antimicrobial activity of extracts from Morus alba L. leaves, stems and fruits. Am J Chin Med. 2012;40:349-56 pubmed
    In this study, the aqueous and ethanolic extracts (leaves, stems and fruits) from Morus alba L., a traditional Chinese medicine, were evaluated for their antioxidant and antimicrobial properties...
  45. Deepa M, Priya S. Purification and characterization of a novel anti-proliferative lectin from Morus alba L. leaves. Protein Pept Lett. 2012;19:839-45 pubmed
    A novel anti-proliferative lectin was purified from Morus alba L...
  46. Checker V, Chhibbar A, Khurana P. Stress-inducible expression of barley Hva1 gene in transgenic mulberry displays enhanced tolerance against drought, salinity and cold stress. Transgenic Res. 2012;21:939-57 pubmed publisher
    ..Although conventional breeding and marker-assisted selection are being employed in mulberry (Morus indica L...
  47. Kim G, Jang H. Flavonol content in the water extract of the mulberry (Morus alba L.) leaf and their antioxidant capacities. J Food Sci. 2011;76:C869-73 pubmed publisher
    The biological activities of the mulberry (Morus alba?L.) leaf have been attributed to its flavonoid content...
  48. Khurana P, Checker V. The advent of genomics in mulberry and perspectives for productivity enhancement. Plant Cell Rep. 2011;30:825-38 pubmed publisher
    ..The present review article gives a bird's eye view of current initiatives of genomics advancements in mulberry research and enumerates the prospects for enhancing its productivity...
  49. Kim Y, Lee Y, Kim H, Kim J, Jang D, Kim J, et al. Anti-obesity effect of Morus bombycis root extract: anti-lipase activity and lipolytic effect. J Ethnopharmacol. 2010;130:621-4 pubmed
    This study evaluated anti-obesity effect of the ethanolic extract of Morus bombycis root on lipase activity and lipolysis in adipocytes and adipose tissues.
  50. Hansawasdi C, Kawabata J. Alpha-glucosidase inhibitory effect of mulberry (Morus alba) leaves on Caco-2. Fitoterapia. 2006;77:568-73 pubmed
    ..of brewing time on dry weight content and alpha-glucosidase inhibitory active component released from mulberry (Morus alba) tea were studied...
  51. Xia M, Qian L, Zhou X, Gao Q, Bruce I, Xia Q. Endothelium-independent relaxation and contraction of rat aorta induced by ethyl acetate extract from leaves of Morus alba (L.). J Ethnopharmacol. 2008;120:442-6 pubmed publisher
    ..Chinese medicinal herbs, the present study was performed to investigate the vasoactive effects of an ethyl acetate extract from leaves of Morus alba (L.) (ELM) on rat thoracic aorta and the mechanisms underlying these effects.
  52. Andallu B, Varadacharyulu N. Gluconeogenic substrates and hepatic gluconeogenic enzymes in streptozotocin-diabetic rats: effect of mulberry (Morus indica L.) leaves. J Med Food. 2007;10:41-8 pubmed
    Mulberry (Morus indica L.) leaves, the sole food of the silk worm, were evaluated for antidiabetic effects in streptozotocin (STZ)-diabetic rats...
  53. Kuete V, Fozing D, Kapche W, Mbaveng A, Kuiate J, Ngadjui B, et al. Antimicrobial activity of the methanolic extract and compounds from Morus mesozygia stem bark. J Ethnopharmacol. 2009;124:551-5 pubmed publisher
    ..the antimicrobial activity of the methanolic extract (MMB) and compounds isolated from the stem bark of Morus mesozygia, namely 3beta-acetoxyurs-12-en-11-one (1), moracin Q (2), moracin T (3), artocarpesin (4), ..
  54. Zhang Q, Tang Y, Chen R, Yu D. Three new cytotoxic Diels-Alder-type adducts from Morus australis. Chem Biodivers. 2007;4:1533-40 pubmed
    Three new natural products, australisines A-C (1-3, resp.), were isolated from the stem bark of Morus australis, together with eight related compounds, including mulberrofurans E-G, J, and Q, mongolicin C, chalcomoracin, and kuwanon G...
  55. Skupień K, Kostrzewa Nowak D, Oszmianski J, Tarasiuk J. In vitro antileukaemic activity of extracts from chokeberry (Aronia melanocarpa [Michx] Elliott) and mulberry (Morus alba L.) leaves against sensitive and multidrug resistant HL60 cells. Phytother Res. 2008;22:689-94 pubmed publisher
    ..antileukaemic activities of extracts obtained from chokeberry (Aronia melanocarpa [Michx] Elliot) and mulberry (Morus alba L...
  56. Sharma S, Gupta S, Ac R, Singh U, Rajpoot R, Shukla S. Antidiabetogenic action of Morus rubra L. leaf extract in streptozotocin-induced diabetic rats. J Pharm Pharmacol. 2010;62:247-55 pubmed publisher
    ..This study evaluated the antidiabetic action of Morus rubra L...
  57. Hoang D, Ngoc T, Dat N, Ha D, Kim Y, Luong H, et al. Protein tyrosine phosphatase 1B inhibitors isolated from Morus bombycis. Bioorg Med Chem Lett. 2009;19:6759-61 pubmed publisher
    Bioassay-guided fractionation of the chloroform-soluble fraction of Morus bombycis, using an in vitro PTP1B inhibitory assay led to the identification of three 2-arylbenzofurans, albafuran A (1), mulberrofuran W (2) and mulberrofuran D (..
  58. Meneguim A, Lustri C, Oliveira D, Yada I, Pasini A. [Bromatological characterization of mulberry cultivars, Morus spp., and determination of nutritional indexes of Bombyx mori L. (Lepidoptera: Bombycidae)]. Neotrop Entomol. 2010;39:506-12 pubmed
    ..work was to assess, through consumption and utilization of natural food measurements, whether mulberry cultivars, Morus spp., could be recommended to rear the silkworm, Bombyx mori L., in a commercial scale...
  59. Mu Z, Lu G, Ji X, Gai Y, Wang Y, Gao H, et al. [Identification and colonization of an antagonistic endophytic Burkholderia cepacia Lu10-1 isolated from mulberry]. Wei Sheng Wu Xue Bao. 2008;48:623-30 pubmed
    ..To identify and colonize an antagonistic bacterium, Lu10-1, isolated from the healthy mulberry...
  60. Sattayasai J, Tiamkao S, Puapairoj P. Biphasic effects of Morus alba leaves green tea extract on mice in chronic forced swimming model. Phytother Res. 2008;22:487-92 pubmed publisher
    In this study, the effects of an aqueous extract of Morus alba leaves green tea (ME) on mouse behaviors (depression, anxiety, climbing activity and thermal response), muscle coordination and muscle strength were studied...
  61. Deepa M, Sureshkumar T, Satheeshkumar P, Priya S. Antioxidant rich Morus alba leaf extract induces apoptosis in human colon and breast cancer cells by the downregulation of nitric oxide produced by inducible nitric oxide synthase. Nutr Cancer. 2013;65:305-10 pubmed publisher
    b>Morus species had been used widely in the traditional medicines for various diseases. In this study we report the in vitro antiproliferative activity of the methanol extract of Morus alba...
  62. Kapche G, Fozing C, Donfack J, Fotso G, Amadou D, Tchana A, et al. Prenylated arylbenzofuran derivatives from Morus mesozygia with antioxidant activity. Phytochemistry. 2009;70:216-21 pubmed publisher
    Five prenylated arylbenzofurans, moracins Q-U, were isolated from Morus mesozygia (Moraceae). Their structures were elucidated on the basis of spectroscopic evidence...
  63. Hirayama C, Konno K, Wasano N, Nakamura M. Differential effects of sugar-mimic alkaloids in mulberry latex on sugar metabolism and disaccharidases of Eri and domesticated silkworms: enzymatic adaptation of Bombyx mori to mulberry defense. Insect Biochem Mol Biol. 2007;37:1348-58 pubmed
    Mulberry leaves (Morus spp.) exude latex rich in sugar-mimic alkaloids, 1,4-dideoxy-1,4-imino-d-arabinitol (d-AB1) and 1-deoxynojirimycin (DNJ), as a defense against herbivorous insects...
  64. Yang Z, Matsuzaki K, Takamatsu S, Kitanaka S. Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells. Molecules. 2011;16:6010-22 pubmed publisher
    ..7-O-?-D-apiofuranosyl-(1?6)-O-?-D-glucopyranoside (25) and adenosine (26), were isolated from Morus alba var. multicaulis Perro. (Moraceae). Their structures were determined by spectroscopic methods...
  65. Jin Y, Kim M, Heo S, Han W, Wang M. Identification and properties of 2,5-dihydroxy-4,3'-di(beta-D-glucopyranosyloxy)-trans-stilbene from Morus bombycis Koidzumi roots. Phytother Res. 2007;21:605-8 pubmed
    2,5-Dihydroxy-4,3'-di(beta-d-glucopyranosyloxy)-trans-stilbene was identified from Morus bombycis Koidzumi roots...
  66. Naowaratwattana W, De Eknamkul W, de Mejia E. Phenolic-containing organic extracts of mulberry (Morus alba L.) leaves inhibit HepG2 hepatoma cells through G2/M phase arrest, induction of apoptosis, and inhibition of topoisomerase II? activity. J Med Food. 2010;13:1045-56 pubmed publisher
    The entire plant of Morus alba L. (Family Moraceae), or mulberry, possesses medical benefits, including anticancer properties...
  67. Srivastava S, Kapoor R, Thathola A, Srivastava R. Nutritional quality of leaves of some genotypes of mulberry (Morus alba). Int J Food Sci Nutr. 2006;57:305-13 pubmed
    ..00-35.72 mg/100 g, 0.72-3.65 mg/100 g and 786.66-2226.66 mg/100 g, respectively, for dried mulberry leaf powder. The tannic acid ranged from 0.04 to 0.08% in fresh leaves and from 0.13 to 0.36% in dried leaf powder...
  68. Wasano N, Konno K, Nakamura M, Hirayama C, Hattori M, Tateishi K. A unique latex protein, MLX56, defends mulberry trees from insects. Phytochemistry. 2009;70:880-8 pubmed publisher
    The mulberry (Morus spp.)-silkworm (Bombyx mori) relationship has been a well-known plant-herbivore interaction for thousands of years. Recently, we found that mulberry leaves defend against insect herbivory by latex ingredients...
  69. Takahashi M, Takara K, Toyozato T, Wada K. A novel bioactive chalcone of Morus australis inhibits tyrosinase activity and melanin biosynthesis in B16 melanoma cells. J Oleo Sci. 2012;61:585-92 pubmed
    The methanol extract of Morus australis (shimaguwa) acts as a whitening agent due to the inhibition of tyrosinase activity...
  70. Jeong S, Ryu Y, Curtis Long M, Ryu H, Baek Y, Kang J, et al. Tyrosinase inhibitory polyphenols from roots of Morus lhou. J Agric Food Chem. 2009;57:1195-203 pubmed publisher
    ..polyphenols (1-12) possessing tyrosinase inhibitory properties were isolated from the methanol (95%) extract of Morus lhou...
  71. Serencam H, Ozdes D, Duran C, Tufekci M. Biosorption properties of Morus alba L. for Cd (II) ions removal from aqueous solutions. Environ Monit Assess. 2013;185:6003-11 pubmed publisher
    The abundantly available industrial waste product Morus alba L. pomace (MAP) is one of the cost-effective biosorbent for removal of metal ions from aqueous solutions...
  72. Ryu Y, Ha T, Curtis Long M, Ryu H, Gal S, Park K. Inhibitory effects on mushroom tyrosinase by flavones from the stem barks of Morus lhou (S.) Koidz. J Enzyme Inhib Med Chem. 2008;23:922-30 pubmed
    Five flavones displaying tyrosinase inhibitory activity were isolated from the stem barks of Morus lhou (S.) Koidz., a cultivated edible plant...
  73. Sharma S, Tanwar R, Rini A, Singh U, Gupta S, Shukla S. Protective effect of Morus rubra L. leaf extract on diet-induced atherosclerosis in diabetic rats. Indian J Biochem Biophys. 2010;47:26-31 pubmed
    The antiatherosclerotic effect of aqueous leaves extract of Morus rubra was studied in streptozotocin-induced diabetic rats fed with atherosclerotic (Ath) diet [1...
  74. Yang Y, Zhang T, Xiao L, Yang L, Chen R. Two new chalcones from leaves of Morus alba L. Fitoterapia. 2010;81:614-6 pubmed publisher
    Two new chalcone derivatives named morachalcones B and C (1 and 2) were isolated from the leaves of Morus alba L. Their structures were elucidated by spectroscopic analysis...
  75. Das M, Chauhan H, Chhibbar A, Rizwanul Haq Q, Khurana P. High-efficiency transformation and selective tolerance against biotic and abiotic stress in mulberry, Morus indica cv. K2, by constitutive and inducible expression of tobacco osmotin. Transgenic Res. 2011;20:231-46 pubmed publisher
    ..We therefore conclude that 35S transgenic plants are better suited for both abiotic stress also biotic challenges (fungal), while the rd29A transgenic plants are more responsive to drought...
  76. Khan M, Rahman A, Islam S, Khandokhar P, Parvin S, Islam M, et al. A comparative study on the antioxidant activity of methanolic extracts from different parts of Morus alba L. (Moraceae). BMC Res Notes. 2013;6:24 pubmed publisher
    ..and phenolic contents (total phenols, flavonoids, flavonols and proanthrocyanidins) of methanolic extracts from Morus alba (locally named as Tut and commonly known as white mulberry) stem barks (TSB), root bark (TRB), leaves (TL) ..
  77. Kobayashi Y, Miyazawa M, Kamei A, Abe K, Kojima T. Ameliorative effects of mulberry (Morus alba L.) leaves on hyperlipidemia in rats fed a high-fat diet: induction of fatty acid oxidation, inhibition of lipogenesis, and suppression of oxidative stress. Biosci Biotechnol Biochem. 2010;74:2385-95 pubmed
    To determine the effects of mulberry (Morus alba L.) leaves on hyperlipidemia, we performed gene expression profiling of the liver. Rats were fed a high-fat diet and administered mulberry leaves for 7 weeks...
  78. Islam B, Khan S, Haque I, Alam M, Mushfiq M, Khan A. Novel anti-adherence activity of mulberry leaves: inhibition of Streptococcus mutans biofilm by 1-deoxynojirimycin isolated from Morus alba. J Antimicrob Chemother. 2008;62:751-7 pubmed publisher
    The present study focused on isolation, characterization and evaluation of purified compounds from Morus alba against Streptococcus mutans biofilm formation.