artocarpus

Summary

Summary: A plant genus of the family MORACEAE. Puag-haad extract, from A. lakoocha, contains STILBENES and related 4-substituted RESORCINOLS.

Top Publications

  1. Khan M, Omoloso A, Kihara M. Antibacterial activity of Artocarpus heterophyllus. Fitoterapia. 2003;74:501-5 pubmed
    The crude methanolic extracts of the stem and root barks, stem and root heart-wood, leaves, fruits and seeds of Artocarpus heterophyllus and their subsequent partitioning with petrol, dichloromethane, ethyl acetate and butanol gave ..
  2. Wang Y, Hou A, Chen L, Chen D, Sun H, Zhao Q, et al. New isoprenylated flavones, artochamins A--E, and cytotoxic principles from Artocarpus chama. J Nat Prod. 2004;67:757-61 pubmed
    ..flavones, artochamins A-E (1-5), together with eight known flavones (6-13), were isolated from the roots of Artocarpus chama. All structures were elucidated by spectroscopic methods...
  3. Seo E, Lee D, Shin Y, Chai H, Navarro H, Kardono L, et al. Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando. Arch Pharm Res. 2003;26:124-7 pubmed
    ..E (1) and O (2), artobiloxanthone (3), and cycloartobiloxanthone (4), were isolated from the stem bark of Artocarpus kemando by bioassay-guided fractionation using the DNA strand-scission and the KB cytotoxicity assays as ..
  4. Jayasinghe L, Balasooriya B, Padmini W, Hara N, Fujimoto Y. Geranyl chalcone derivatives with antifungal and radical scavenging properties from the leaves of Artocarpus nobilis. Phytochemistry. 2004;65:1287-90 pubmed
    Antifungal activity guided fractionation of the n-butanol extract from the methanol extract of the leaves of Artocarpus nobilis furnished 2',4',4-trihydroxy-3'-geranylchalcone (1), 2 ',4',4-trihydroxy-3'-[6-hydroxy-3,7-dimethyl-2(E),7-..
  5. Wang Y, Deng T, Lin L, Pan Y, Zheng X. Bioassay-guided isolation of antiatherosclerotic phytochemicals from Artocarpus altilis. Phytother Res. 2006;20:1052-5 pubmed
    The cytoprotective effects of various solvent extracts of Artocarpus altilis (Parkinson) Fosberg were evaluated...
  6. Chatterjee U, Bose P, Dey S, Singh T, Chatterjee B. Antiproliferative effect of T/Tn specific Artocarpus lakoocha agglutinin (ALA) on human leukemic cells (Jurkat, U937, K562) and their imaging by QD-ALA nanoconjugate. Glycoconj J. 2008;25:741-52 pubmed publisher
    T/Tn specificity of Artocarpus lakoocha agglutinin (ALA), isolated from the seeds of A...
  7. Jayasinghe U, Samarakoon T, Kumarihamy B, Hara N, Fujimoto Y. Four new prenylated flavonoids and xanthones from the root bark of Artocarpus nobilis. Fitoterapia. 2008;79:37-41 pubmed
    Chemical investigation of the n-butanol extract from the methanol extract of the root bark of Artocarpus nobilis furnished four new prenylated flavonoids together with artonin E 2'-methylether (4), isoartonin E 2'-methylether (5), ..
  8. Pitaksuteepong T, Somsiri A, Waranuch N. Targeted transfollicular delivery of artocarpin extract from Artocarpus incisus by means of microparticles. Eur J Pharm Biopharm. 2007;67:639-45 pubmed
    Artocarpin (Ar), an extract of heartwood of Artocarpus incisus, possesses potent 5alpha reductase inhibitory effect. The penetration of Ar into the deeper layers of the skin where androgen receptors are present is limited...
  9. Sidahmed H, Hashim N, Amir J, Abdulla M, Hadi A, Abdelwahab S, et al. Pyranocycloartobiloxanthone A, a novel gastroprotective compound from Artocarpus obtusus Jarret, against ethanol-induced acute gastric ulcer in vivo. Phytomedicine. 2013;20:834-43 pubmed publisher
    Pyranocycloartobiloxanthone A (PA), a xanthone derived from the Artocarpus obtusus Jarret, belongs to the Moraceae family which is native to the tropical forest of Malaysia...

More Information

Publications92

  1. Wei B, Weng J, Chiu P, Hung C, Wang J, Lin C. Antiinflammatory flavonoids from Artocarpus heterophyllus and Artocarpus communis. J Agric Food Chem. 2005;53:3867-71 pubmed
    ..A (9) and B (10), artocarpanone (11), artocarpanone A (12), and heteroflavanones A (13), B (14), and C (15) from Artocarpus communis and A...
  2. Lin J, Fang S, Wu C, Huang S, Yen G. Anti-inflammatory effect of the 5,7,4'-trihydroxy-6-geranylflavanone isolated from the fruit of Artocarpus communis in S100B-induced human monocytes. J Agric Food Chem. 2011;59:105-11 pubmed publisher
    The fruit of Artocarpus communis Moraceae, a traditional starch crop, is a rich source of phytochemicals, such as flavonoids and their derivatives...
  3. Hashim N, Rahmani M, Sukari M, Ali A, Alitheen N, Go R, et al. Two new xanthones from Artocarpus obtusus. J Asian Nat Prod Res. 2010;12:106-12 pubmed publisher
    ..pyranocycloartobiloxanthone A (1) and dihydroartoindonesianin C (2), were isolated from the stem bark of Artocarpus obtusus Jarrett by chromatographic separation...
  4. Zhao T, Yan G, Pan S, Wang H, Hou A. New isoprenylated 2-arylbenzofurans and pancreatic lipase inhibitory constituents from Artocarpus nitidus. Chem Biodivers. 2009;6:2209-16 pubmed publisher
    ..together with 14 known compounds, were isolated from the stems of Artocarpus nitidus Trec. The structures were elucidated by spectroscopic methods...
  5. Fang S, Hsu C, Yen G. Anti-inflammatory effects of phenolic compounds isolated from the fruits of Artocarpus heterophyllus. J Agric Food Chem. 2008;56:4463-8 pubmed publisher
    b>Artocarpus heterophyllus Lam is a large evergreen tree cultivated throughout Southeast Asia for its fruits. Its leaves and roots have been used for medicinal purposes...
  6. Fang S, Hsu C, Yu Y, Yen G. Cytotoxic effects of new geranyl chalcone derivatives isolated from the leaves of Artocarpus communis in SW 872 human liposarcoma cells. J Agric Food Chem. 2008;56:8859-68 pubmed publisher
    Breadfruit (Artocarpus communis Moraceae) is cultivated in tropical and subtropical regions as a traditional starch crop and also has potential medicinal properties...
  7. Arung E, Shimizu K, Kondo R. Inhibitory effect of artocarpanone from Artocarpus heterophyllus on melanin biosynthesis. Biol Pharm Bull. 2006;29:1966-9 pubmed
    ..Among those plants, the extract of Artocarpus heterophyllus was one of the strongest inhibitors of tyrosinase activity. By activity-guided fractionation of A...
  8. Kuete V, Ango P, Fotso G, Kapche G, Dzoyem J, Wouking A, et al. Antimicrobial activities of the methanol extract and compounds from Artocarpus communis (Moraceae). BMC Complement Altern Med. 2011;11:42 pubmed publisher
    b>Artocarpus communis is used traditionally in Cameroon to treat several ailments, including infectious and associated diseases...
  9. Coltri K, Oliveira L, Ruas L, Vendruscolo P, Goldman M, Panunto Castelo A, et al. Protection against Paracoccidioides brasiliensis infection conferred by the prophylactic administration of native and recombinant ArtinM. Med Mycol. 2010;48:792-9 pubmed publisher
    We determined the prophylactic effect of both the d-mannose-binding lectin ArtinM extracted from the seeds of Artocarpus integrifolia (jackfruit) and its recombinant counterpart during the course of experimental paracoccidioidomycosis ..
  10. Maneechai S, De Eknamkul W, Umehara K, Noguchi H, Likhitwitayawuid K. Flavonoid and stilbenoid production in callus cultures of Artocarpus lakoocha. Phytochemistry. 2012;81:42-9 pubmed publisher
    Callus cultures of Artocarpus lakoocha Roxb...
  11. Coltri K, Oliveira L, Pinzan C, Vendruscolo P, Martinez R, Goldman M, et al. Therapeutic administration of KM+ lectin protects mice against Paracoccidioides brasiliensis infection via interleukin-12 production in a toll-like receptor 2-dependent mechanism. Am J Pathol. 2008;173:423-32 pubmed publisher
    KM(+) is a mannose-binding lectin from Artocarpus integrifolia that induces interleukin (IL)-12 production by macrophages and protective T helper 1 immune response against Leishmania major infection...
  12. Arung E, Shimizu K, Kondo R. Inhibitory effect of isoprenoid-substituted flavonoids isolated from Artocarpus heterophyllus on melanin biosynthesis. Planta Med. 2006;72:847-50 pubmed
    Isoprenoid-substituted flavonoids were isolated from the wood of Artocarpus heterophyllus by means of activity-guided fractionation...
  13. Weng J, Chan S, Lu Y, Lin H, Ko H, Lin C. Antiplatelet prenylflavonoids from Artocarpus communis. Phytochemistry. 2006;67:824-9 pubmed
    ..known compounds, artochamins B (5), D and artocommunol CC (6) were isolated from the cortex of the roots of Artocarpus communis. The structures of 1-4 were determined by spectroscopic methods...
  14. Lan W, Tzeng C, Lin C, Yen F, Ko H. Prenylated flavonoids from Artocarpus altilis: antioxidant activities and inhibitory effects on melanin production. Phytochemistry. 2013;89:78-88 pubmed publisher
    ..4), and furanocyclocommunin (5), together with 12 known compounds, were isolated from heartwood and cortex of Artocarpus altilis, and their structures were identified by comparing their spectra with those of similar compounds...
  15. Jagtap U, Bapat V. Artocarpus: a review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol. 2010;129:142-66 pubmed publisher
    The genus Artocarpus (Moraceae) comprises about 50 species of evergreen and deciduous trees. Economically, the genus is of appreciable importance as a source of edible fruit, yield fairly good timber and is widely used in folk medicines...
  16. Wu A, Wu J, Lin L, Lin S, Liu J. Binding profile of Artocarpus integrifolia agglutinin (Jacalin). Life Sci. 2003;72:2285-302 pubmed
    b>Artocarpus integrifolia agglutinin (Jacalin) from the seeds of jack fruits has attracted considerable attention for its diverse biological activities and has been recognized as a Galbeta1-->3GalNAc (T) specific lectin...
  17. Madruga M, de Albuquerque F, Silva I, do Amaral D, Magnani M, Queiroga Neto V. Chemical, morphological and functional properties of Brazilian jackfruit (Artocarpus heterophyllus L.) seeds starch. Food Chem. 2014;143:440-5 pubmed publisher
    ..These results suggest that the Brazilian jackfruit seeds starches could be used in food products. ..
  18. Likhitwitayawuid K, Sritularak B, Benchanak K, Lipipun V, Mathew J, Schinazi R. Phenolics with antiviral activity from Millettia erythrocalyx and Artocarpus lakoocha. Nat Prod Res. 2005;19:177-82 pubmed
    ..erythrocalyx and Artocarpus lakoocha...
  19. Han A, Kang Y, Windono T, Lee S, Seo E. Prenylated flavonoids from the heartwood of Artocarpus communis with inhibitory activity on lipopolysaccharide-induced nitric oxide production. J Nat Prod. 2006;69:719-21 pubmed
    ..chalcone, 3' ',3' '-dimethylpyrano[3',4']2,4,2'-trihydroxychalcone (1), was isolated from the heartwood of Artocarpus communis...
  20. Minakawa T, Toume K, Arai M, Koyano T, Kowithayakorn T, Ishibashi M. Prenylflavonoids isolated from Artocarpus champeden with TRAIL-resistance overcoming activity. Phytochemistry. 2013;96:299-304 pubmed publisher
    ..ligand (TRAIL)-resistance, three prenylflavonoids, named pannokin A-C, were isolated from a MeOH extract of Artocarpus champeden (Moraceae) roots, together with three known prenylflavonoids...
  21. Soekamto N, Achmad S, Ghisalberti E, Hakim E, Syah Y. Artoindonesianins X and Y, two isoprenylated 2-arylbenzofurans, from Artocarpus fretessi (Moraceae). Phytochemistry. 2003;64:831-4 pubmed
    ..X and Y (1-2), together with seven known flavonoids, have been isolated from the roots and tree bark of Artocarpus fretessi. Their structures were established on the basis of spectral analysis...
  22. Hsu C, Chang F, Tseng P, Chen Y, El Shazly M, Du Y, et al. Geranyl flavonoid derivatives from the fresh leaves of Artocarpus communis and their anti-inflammatory activity. Planta Med. 2012;78:995-1001 pubmed publisher
    Breadfruit (Artocarpus communis) is a widely distributed crop in tropical and subtropical regions of the world. It is used in Southeast Asia and India to treat several inflammatory disorders...
  23. Arung E, Shimizu K, Kondo R. Structure-activity relationship of prenyl-substituted polyphenols from Artocarpus heterophyllus as inhibitors of melanin biosynthesis in cultured melanoma cells. Chem Biodivers. 2007;4:2166-71 pubmed
    A series of prenylated, flavone-based polyphenols, compounds 1-8, were isolated from the wood of Artocarpus heterophyllus...
  24. Arung E, Shimizu K, Tanaka H, Kondo R. 3-Prenyl luteolin, a new prenylated flavone with melanin biosynthesis inhibitory activity from wood of Artocarpus heterophyllus. Fitoterapia. 2010;81:640-3 pubmed publisher
    In our efforts to find new whitening agent from natural resources, we focused on wood of Artocarpus heterophyllus which shows anti-melanogenesis activity. By activity-guided fractionation of A...
  25. Cardoso M, Mota C, Ribeiro D, Santiago F, Carvalho J, Araujo E, et al. ArtinM, a D-mannose-binding lectin from Artocarpus integrifolia, plays a potent adjuvant and immunostimulatory role in immunization against Neospora caninum. Vaccine. 2011;29:9183-93 pubmed publisher
    ArtinM and Jacalin (JAC) are lectins from the jackfruit (Artocarpus integrifolia) that have important role in modulation of immune responses to pathogens...
  26. Lotulung P, Fajriah S, Hanafi M, Filaila E. Identification of cytotoxic compound from Artocarpus communis leaves against P-388 cells. Pak J Biol Sci. 2008;11:2517-20 pubmed
    In the course of continuing research for finding bioactive compounds from Indonesian plants, the leaves of Artocarpus communis was extracted by ethanol...
  27. daSilva L, de Molfetta Machado J, Panunto Castelo A, Denecke J, Goldman G, Roque Barreira M, et al. cDNA cloning and functional expression of KM+, the mannose-binding lectin from Artocarpus integrifolia seeds. Biochim Biophys Acta. 2005;1726:251-60 pubmed
    KM+, a mannose-binding lectin present in the seeds of Artocarpus integrifolia, has interesting biological properties and potential pharmaceutical use [A. Panunto-Castelo, M.A. Souza, M.C. Roque-Barreira, J.S...
  28. Arung E, Yoshikawa K, Shimizu K, Kondo R. Isoprenoid-substituted flavonoids from wood of Artocarpus heterophyllus on B16 melanoma cells: cytotoxicity and structural criteria. Fitoterapia. 2010;81:120-3 pubmed publisher
    ..B (7), brosimone I (8) and artocarpanone (9) were identified from the methanol extract of the wood of Artocarpus heterophyllus, known commonly as Nangka in Indonesia...
  29. Jamil S, Sirat H, Jantan I, Aimi N, Kitajima M. A new prenylated dihydrochalcone from the leaves of Artocarpus lowii. J Nat Med. 2008;62:321-4 pubmed publisher
    ..2) and 2',4-dihydroxy-3',4'-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii...
  30. Teixeira C, Cavassani K, Gomes R, Teixeira M, Roque Barreira M, Cavada B, et al. Potential of KM+ lectin in immunization against Leishmania amazonensis infection. Vaccine. 2006;24:3001-8 pubmed
    In the present study we evaluated Canavalia brasiliensis (ConBr), Pisum arvense (PAA) and Artocarpus integrifolia (KM+) lectins as immunostimulatory molecules in vaccination against Leishmania amazonensis infection...
  31. Custódio L, Loyola W, Conchon Costa I, da Silva Quirino G, Felipe I. Protective effect of Artin M from extract of Artocarpus integrifolia seeds by Th1 and Th17 immune response on the course of infection by Candida albicans. Int Immunopharmacol. 2011;11:1510-5 pubmed publisher
    The immunoregulatory effect of Artin M and jacalin from extract of Artocarpus integrifolia seeds (jack extract) against infection with Candida albicans was investigated...
  32. Shamaun S, Rahmani M, Hashim N, Ismail H, Sukari M, Lian G, et al. Prenylated flavones from Artocarpus altilis. J Nat Med. 2010;64:478-81 pubmed publisher
    Six prenylated flavones, including one new compound, were isolated and identified from the stem bark extracts of Artocarpus altilis...
  33. Gaikwad S, Khan M. Binding of T-antigen disaccharides to Artocarpus hirsuta lectin and jacalin are energetically different. Photochem Photobiol. 2006;82:1315-8 pubmed
    ..Gal-beta-1-3GalNAc-alpha-O-Me (T-antigen-alpha), Gal-beta-1-3GalNAc and Gal-alpha-1-6Glc (mellibiose) to Artocarpus hirsuta lectin was studied using fluorescence spectroscopy...
  34. Zheng Z, Cheng K, To J, Li H, Wang M. Isolation of tyrosinase inhibitors from Artocarpus heterophyllus and use of its extract as antibrowning agent. Mol Nutr Food Res. 2008;52:1530-8 pubmed publisher
    ..B (12), carpachromene (13), isoartocarpesin (14), and cyanomaclurin (15) were isolated from the wood of Artocarpus heterophyllus...
  35. Trindade M, Lopes J, Soares Costa A, Monteiro Moreira A, Moreira R, Oliva M, et al. Structural characterization of novel chitin-binding lectins from the genus Artocarpus and their antifungal activity. Biochim Biophys Acta. 2006;1764:146-52 pubmed
    Two novel chitin-binding lectins from seeds of Artocarpus genus were described in this paper, one from A. integrifolia (jackfruit) and one from A. incisa (breadfruit)...
  36. Zheng Z, Chen S, Wang S, Wang X, Cheng K, Wu J, et al. Chemical components and tyrosinase inhibitors from the twigs of Artocarpus heterophyllus. J Agric Food Chem. 2009;57:6649-55 pubmed publisher
    ..validated to compare the chemical profiles and tyrosinase inhibitors in the woods, twigs, roots, and leaves of Artocarpus heterophyllus ...
  37. Nwokocha C, Palacios J, Simirgiotis M, Thomas J, Nwokocha M, Young L, et al. Aqueous extract from leaf of Artocarpus altilis provides cardio-protection from isoproterenol induced myocardial damage in rats: Negative chronotropic and inotropic effects. J Ethnopharmacol. 2017;203:163-170 pubmed publisher
    The leaves of Artocarpus altilis (Parkinson ex F.A...
  38. Rao K, Suresh C, Katre U, Gaikwad S, Khan M. Two orthorhombic crystal structures of a galactose-specific lectin from Artocarpus hirsuta in complex with methyl-alpha-D-galactose. Acta Crystallogr D Biol Crystallogr. 2004;60:1404-12 pubmed
    ..Here, two crystal structures of a jacalin-related lectin from Artocarpus hirsuta, which is specific for galactose, in complex with methyl-alpha-D-galactose are reported...
  39. Fernandez del Carmen A, Juárez P, Presa S, Granell A, Orzaez D. Recombinant jacalin-like plant lectins are produced at high levels in Nicotiana benthamiana and retain agglutination activity and sugar specificity. J Biotechnol. 2013;163:391-400 pubmed publisher
    ..Together, these results show that the plant cell factory should be considered a primary option in the recombinant production of valuable plant proteins. ..
  40. Loyola W, Custódio L, Felipe I, Conchon Costa I, Carvalho P, Quirino G, et al. Artin M enhances TNF-? production and phagocytosis of Candida albicans mediated by dectin-1 and mannose receptors. Int Immunopharmacol. 2012;12:378-83 pubmed publisher
    ..of Candida albicans and the production of TNF-? by macrophages from mice pretreated for 3 days with extract of Artocarpus intergrifolia seeds (jack extract), Artin M or jacalin were studied...
  41. Jin Y, Lin C, Lu T, Li J, Chen I, Kuo Y, et al. Chemical constituents derived from Artocarpus xanthocarpus as inhibitors of melanin biosynthesis. Phytochemistry. 2015;117:424-35 pubmed publisher
    ..Collectively, the results suggest that the constituents of Artocarpus xanthocarpus have potential to be used as depigmentation agents.
  42. Cecílio N, Carvalho F, Liu Y, Moncrieffe M, Buranello P, Zorzetto Fernandes A, et al. Yeast expressed ArtinM shares structure, carbohydrate recognition, and biological effects with native ArtinM. Int J Biol Macromol. 2016;82:22-30 pubmed publisher
    ..ArtinM, a d-mannose-binding lectin isolated from the seeds of jackfruit (Artocarpus heterophyllus), is composed of 16 kDa subunits that are associated to form a homotetramer...
  43. Sugumaran K, Sindhu R, Sukanya S, Aiswarya N, Ponnusami V. Statistical studies on high molecular weight pullulan production in solid state fermentation using jack fruit seed. Carbohydr Polym. 2013;98:854-60 pubmed publisher
    ..The pullulan obtained was characterized and confirmed by FTIR, (1)H NMR and (13)C NMR. Molecular weight of pullulan was found to be 1.733×10(6) g/mol by gel permeation chromatography (GPC). ..
  44. Namdaung U, Aroonrerk N, Suksamrarn S, Danwisetkanjana K, Saenboonrueng J, Arjchomphu W, et al. Bioactive constituents of the root bark of Artocarpus rigidus subsp. rigidus. Chem Pharm Bull (Tokyo). 2006;54:1433-6 pubmed
    Investigation of the chemical constituents of the root bark of Artocarpus rigidus BLUME subsp. rigidus has led to the isolation of six, structurally diverse phenolic compounds...
  45. Tao Y, Yao L, Qin Q, Shen W. Purification and characterization of polyphenol oxidase from jackfruit ( Artocarpus heterophyllus ) bulbs. J Agric Food Chem. 2013;61:12662-9 pubmed publisher
    ..Cys and AA were effective to reduce browning of jackfruit bulbs during the storage at 8 °C for 15 days. ..
  46. Nguyen N, Nguyen M, Nguyen H, Bui N, Nguyen M. Tyrosinase inhibitors from the wood of Artocarpus heterophyllus. J Nat Prod. 2012;75:1951-5 pubmed publisher
    From the methanolic-soluble extract of the wood of Artocarpus heterophyllus, four new flavones, artocarmins A-D (1-4), and three new chalcones, artocarmitins A-C (5-7), have been isolated together with 13 known compounds...
  47. Chan S, Ko H, Lin C. New prenylflavonoids from Artocarpus communis. J Nat Prod. 2003;66:427-30 pubmed
    ..artocommunols CA (1), CB (2), CC (3), CD (4), and CE (5), were isolated from the cortex of the roots of Artocarpus communis, along with the known compound cyclomorusin. The structures of 1-5 were determined by spectral methods.
  48. Lu Y, Sun C, Wang Y, Pan Y. Two-dimensional counter-current chromatography for the preparative separation of prenylflavonoids from Artocarpus altilis. J Chromatogr A. 2007;1151:31-6 pubmed
    ..chromatographic system (2D-CCC) for preparative isolation and purification of three prenylflavonoids from Artocarpus altilis is presented. An upright CCC instrument (CCC1, total capacity: 1600 ml) was used as the first dimension...
  49. Di X, Wang S, Wang B, Liu Y, Yuan H, Lou H, et al. New phenolic compounds from the twigs of Artocarpus heterophyllus. Drug Discov Ther. 2013;7:24-8 pubmed
    ..one new 2-arylbenzofuran derivative, artocarstilene A (4), and 15 flavonoids were isolated from the twigs of Artocarpus heterophyllus. Their structures were established on the basis of extensive spectroscopic analysis...
  50. Shen H, Hou A. Prenylated 2-arylbenzofurans from Artocarpus petelotii. Nat Prod Res. 2008;22:1451-6 pubmed publisher
    Further phytochemical investigation on the root barks of Artocarpus petelotii Gagnep afforded two new prenylated 2-arylbenzofurans, artopetelins L and M (1 and 2), as well as a known compound, lakoochin B (3)...
  51. Rahman M, Alam M, Hossain M, Miah M. Effect of seasonal variations on jackfruit trunk borer (Batocera rufomaculata De Geer) infestation. Pak J Biol Sci. 2013;16:339-44 pubmed
    ..4% of the total variance. Stepwise regression showed that maximum temperature was the most important to influence 35.3% and the influence was lowest (2.1%) in case of average rainfall. ..
  52. Sritularak B, Tantrakarnsakul K, Likhitwitayawuid K, Lipipun V. New 2-arylbenzofurans from the root bark of Artocarpus lakoocha. Molecules. 2010;15:6548-58 pubmed publisher
    ..artolakoochol, 4-hydroxy-artolakoochol and cycloartolakoochol - have been isolated from the root bark of Artocarpus lakoocha Roxb...
  53. Oliveira C, Costa S, Teixeira J, Domingues L. cDNA cloning and functional expression of the alpha-D-galactose-binding lectin frutalin in Escherichia coli. Mol Biotechnol. 2009;43:212-20 pubmed publisher
    cDNA clones encoding frutalin, the alpha-D-galactose-binding lectin expressed in breadfruit seeds (Artocarpus incisa), were isolated and sequenced...
  54. Lee C, Muthusamy A, Abdul Rahman P, Bhavanandan V, Hashim O. An improved lectin-based method for the detection of mucin-type O-glycans in biological samples. Analyst. 2013;138:3522-9 pubmed publisher
    ..Finally, the applicability of the developed sandwich ELLA to crude samples was demonstrated by estimating trace quantities of the mucin-type O-glycans in the human serum. ..
  55. Thuy T, Kamperdick C, Ninh P, Lien T, Thao T, Sung T. Immunosuppressive auronol glycosides from Artocarpus tonkinensis. Pharmazie. 2004;59:297-300 pubmed
    Activity-guided fractionation of the n-butanol extract from the leaves of Artocarpus tonkinensis led to the isolation of the auronol glycosides maesopsin 4-O-glucoside (1), as well as the new alphitonin-4-O-glucoside (2)...
  56. Aftab N, Likhitwitayawuid K, Vieira A. Comparative antioxidant activities and synergism of resveratrol and oxyresveratrol. Nat Prod Res. 2010;24:1726-33 pubmed publisher
    ..The latter suggests different synergy mechanisms of the curcuminoid with each of the two stilbene phytoalexins...
  57. Arung E, Shimizu K, Kondo R. Artocarpus plants as a potential source of skin whitening agents. Nat Prod Commun. 2011;6:1397-402 pubmed
    b>Artocarpus plants have been a focus of constant attention due to the potential for skin whitening agents...
  58. Saha P, Chakraborty S, Chowdhury S. Batch and continuous (fixed-bed column) biosorption of crystal violet by Artocarpus heterophyllus (jackfruit) leaf powder. Colloids Surf B Biointerfaces. 2012;92:262-70 pubmed publisher
    In this study, batch and fixed-bed column experiments were performed to investigate the biosorption potential of Artocarpus heterophyllus (jackfruit) leaf powder (JLP) to remove crystal violet (CV) from aqueous solutions...
  59. Syah Y, Achmad S, Ghisalberti E, Hakim E, Makmur L, Mujahidin D. Artoindonesianins Q-T, four isoprenylated flavones from Artocarpus champeden Spreng. (Moraceae). Phytochemistry. 2002;61:949-53 pubmed
    Four isoprenylated flavones, artoindonesianins Q-T, were isolated from the heartwood of Artocarpus champeden Roxb. The structures of these compounds were elucidated on the basis of their spectroscopic data.
  60. Hashim N, Rahmani M, Ee G, Sukari M, Yahayu M, Oktima W, et al. Antiproliferative activity of xanthones isolated from Artocarpus obtusus. J Biomed Biotechnol. 2012;2012:130627 pubmed publisher
    An investigation of the chemical constituents in Artocarpus obtusus species led to the isolation of three new xanthones, pyranocycloartobiloxanthone A (1), dihydroartoindonesianin C (2), and pyranocycloartobiloxanthone B (3)...
  61. Nayak A, Pal D, Hasnain S. Development, optimization and in vitro-in vivo evaluation of pioglitazone- loaded jackfruit seed starch-alginate beads. Curr Drug Deliv. 2013;10:608-19 pubmed
    ..The optimized pioglitazone-loaded JFSS-alginate beads showed significant hypoglycemic effect in alloxan-induced diabetic rats over prolonged period after oral administration. ..
  62. Dang D, Eriste E, Liepinsh E, Trinh T, Erlandsson Harris H, Sillard R, et al. A novel anti-inflammatory compound, artonkin-4'-O-glucoside, from the leaves of Artocarpus tonkinensis suppresses experimentally induced arthritis. Scand J Immunol. 2009;69:110-8 pubmed publisher
    b>Artocarpus tonkinenesis (Moraceae) has been used in Vietnamese traditional medicine for the treatment of backache and joint diseases since many 100 years. We have previously shown that a crude extract of A...
  63. Soubir T. Antioxidant activities of some local bangladeshi fruits (Artocarpus heterophyllus, Annona squamosa, Terminalia bellirica, Syzygium samarangense, Averrhoa carambola and Olea europa). Sheng Wu Gong Cheng Xue Bao. 2007;23:257-61 pubmed
    ..bellirica, O. europa, S. samarangense, A. squamosa and A. heterophyllus indicating that fruits of A. carambola, T. bellirica and O. europa are very beneficial to human health. ..
  64. Rincón A, Bou Rached L, Aragoza L, Padilla F. [Effect of acetylation and oxidation on some properties of breadfruit (Artocarpus altilis) seed starch]. Arch Latinoam Nutr. 2007;57:287-94 pubmed
    Starch extracted from seeds of Artocarpus altilis (Breadfruit) was chemically modified by acetylation and oxidation, and its functional properties were evaluated and compared with these of native starch...
  65. Yeh C, Chen C, Leu Y, Lin M, Chiu M, Wang S. The effects of artocarpin on wound healing: in vitro and in vivo studies. Sci Rep. 2017;7:15599 pubmed publisher
    ..Artocarpin (ARTO), a prenylated flavonoid purified from the plant Artocarpus communis, has been reported to have anti-inflammatory and anti-cancer properties...
  66. Bolhaar S, Ree R, Bruijnzeel Koomen C, Knulst A, Zuidmeer L. Allergy to jackfruit: a novel example of Bet v 1-related food allergy. Allergy. 2004;59:1187-92 pubmed
    ..All five had OA-like symptoms. Jackfruit allergy can be added to the list of birchpollen-related food allergies. Increased consumption of this fruit will result in a rise in allergic reactions. ..
  67. Ajayi I. Comparative study of the chemical composition and mineral element content of Artocarpus heterophyllus and Treculia africana seeds and seed oils. Bioresour Technol. 2008;99:5125-9 pubmed
    A comparative study of Artocarpus heterophyllus and Treculia africana seeds, both of Moraceae family, was carried out to establish their chemical compositions and evaluate their mineral element content in order to investigate the ..
  68. Jeyaprakash A, Geetha Rani P, Banuprakash Reddy G, Banumathi S, Betzel C, Sekar K, et al. Crystal structure of the jacalin-T-antigen complex and a comparative study of lectin-T-antigen complexes. J Mol Biol. 2002;321:637-45 pubmed
    ..Jacalin, a lectin from jack fruit (Artocarpus integrifolia) seeds, is a tetramer of molecular mass 66kDa...
  69. Jayasinghe L, Rupasinghe G, Hara N, Fujimoto Y. Geranylated phenolic constituents from the fruits of Artocarpus nobilis. Phytochemistry. 2006;67:1353-8 pubmed
    Chemical investigation of the combined dichloromethane and ethyl acetate extracts of the fruits of Artocarpus nobilis, furnished four new geranylated phenolic constituents, 2,4,4'-trihydroxy-3-[(2E)-5-methoxy-3,7-dimethylocta-2,6-dienyl]..
  70. Musthapa I, Juliawaty L, Syah Y, Hakim E, Latip J, Ghisalberti E. An oxepinoflavone from Artocarpus elasticus with cytotoxic activity against P-388 cells. Arch Pharm Res. 2009;32:191-4 pubmed publisher
    A new oxepinoflavone, artoindonesianin E1 (1), was isolated from the wood of Artocarpus elasticus, along with four known prenylated flavones: artocarpin (2), cycloartocarpin (3), cudraflavones A (4) and C (5)...
  71. Gabrielsen M, Riboldi Tunnicliffe A, Abdul Rahman P, Mohamed E, Ibrahim W, Hashim O, et al. Crystallization and preliminary structural studies of champedak galactose-binding lectin. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009;65:895-7 pubmed publisher
    Galactose-binding lectin from champedak (Artocarpus integer) consists of two chains: alpha and beta (133 and 21 amino acids, respectively)...
  72. Ramadas N, Soccol C, Pandey A. A statistical approach for optimization of polyhydroxybutyrate production by Bacillus sphaericus NCIM 5149 under submerged fermentation using central composite design. Appl Biochem Biotechnol. 2010;162:996-1007 pubmed publisher
    ..This is the first report on PHB production by Bacillus sphaericus using statistical experimental design and RSM in submerged fermentation with jackfruit seed hydrolysate as the sole source of carbon...
  73. Tan Y, Li H, Lai W, Zhang J. Crude dietary polysaccharide fraction isolated from jackfruit enhances immune system activity in mice. J Med Food. 2013;16:663-8 pubmed publisher
    ..5 mg/kg. The JFP contains single molecular PS and JFP-PS has immune-stimulating activities in mice. These data suggest that at least some of the traditional uses of JFP can be ascribed to its immunomodulatory effects...
  74. Huong T, Cuong N, Tram L, Quang T, Duong L, Nam N, et al. A new prenylated aurone from Artocarpus altilis. J Asian Nat Prod Res. 2012;14:923-8 pubmed publisher
    Phytochemical study of the methanol extract of Artocarpus altilis resulted in the isolation of a new prenylated aurone, artocarpaurone (1), together with eight known compounds including two prenylated chalcones (2 and 3), three prenylated ..
  75. Likhitwitayawuid K, Chaiwiriya S, Sritularak B, Lipipun V. Antiherpetic flavones from the heartwood of Artocarpus gomezianus. Chem Biodivers. 2006;3:1138-43 pubmed
    The heartwood of Artocarpus gomezianus was investigated for anti-herpetic principles...
  76. Ling L, Radhakrishnan A, Subramaniam T, Cheng H, Palanisamy U. Assessment of antioxidant capacity and cytotoxicity of selected Malaysian plants. Molecules. 2010;15:2139-51 pubmed publisher
    Thirteen Malaysian plants; Artocarpus champeden, Azadirachta indica, Fragaria x ananassa, Garcinia mangostana, Lawsonia inermis, Mangifera indica, Nephelium lappaceum, Nephelium mutobile, Peltophorum pterocarpum, Psidium guajava and ..
  77. Ko H, Tsai Y, Yen M, Lin C, Liang C, Yang T, et al. Norartocarpetin from a folk medicine Artocarpus communis plays a melanogenesis inhibitor without cytotoxicity in B16F10 cell and skin irritation in mice. BMC Complement Altern Med. 2013;13:348 pubmed publisher
    ..Norartocarpetin is one of the antioxidant and antityrosinase activity compound in Artocarpus communis; however, the cytotoxicity, skin irritation and antimelanogenesis mechanisms of norartocarpetin have ..
  78. Qiao X, Zhao T, Wang M, Lei C, Hou A. [Flavonoids from Artocarpus hypargyreus]. Zhongguo Zhong Yao Za Zhi. 2011;36:2975-9 pubmed
    To investigate flavonoids from Artocarpus hypargyreus.
  79. Inbaraj B, Sulochana N. Carbonised jackfruit peel as an adsorbent for the removal of Cd(II) from aqueous solution. Bioresour Technol. 2004;94:49-52 pubmed
    The fruit of the jack (Artocarpus heterophyllus) is one of the popular fruits in India, where the total area under this fruit is about 13,460 ha...
  80. Paduraru M, Wilson P. Synthesis of the polycyclic ring systems of artocarpol A and D. Org Lett. 2003;5:4911-3 pubmed
    ..These natural products were isolated recently from the root bark of Artocarpus rigida, and artocarpol A has been shown to have potent antiinflammatory properties...
  81. Jones A, Klun J, Cantrell C, Ragone D, Chauhan K, Brown P, et al. Isolation and identification of mosquito (Aedes aegypti ) biting deterrent fatty acids from male inflorescences of breadfruit (Artocarpus altilis (Parkinson) Fosberg). J Agric Food Chem. 2012;60:3867-73 pubmed publisher
    Dried male inflorescences of breadfruit ( Artocarpus altilis , Moraceae) are burned in communities throughout Oceania to repel flying insects, including mosquitoes...
  82. de Faria A, de Rosso V, Mercadante A. Carotenoid composition of jackfruit (Artocarpus heterophyllus), determined by HPLC-PDA-MS/MS. Plant Foods Hum Nutr. 2009;64:108-15 pubmed publisher
    ..The carotenoid composition of jackfruit was successfully determined, where 14 of the 18 identified carotenoids were reported for first time. Differences among batches may be due to genetic and/or agricultural factors...
  83. Jayasinghe U, Puvanendran S, Hara N, Fujimoto Y. Stilbene derivatives with antifungal and radical scavenging properties from the stem bark of Artocarpus nobilis. Nat Prod Res. 2004;18:571-4 pubmed
    Antifungal activity-guided fractionation of the n-butanol extract from the methanol extract of the stem bark of Artocarpus nobilis furnished two stilbene derivatives (E)-4-isopentenyl-3,5,2',4'-tetrahydroxystilbene and (E)-4-(3-methyl-E-..