calophyllum

Summary

Summary: A plant genus of the family CLUSIACEAE. Members contain costatolide, calanolides and 4-phenylfuranocoumarins (FUROCOUMARINS).

Top Publications

  1. Ma C, Chen B, Qi H, Li B, Zhang G. Two pyranocoumarins from the seeds of Calophyllum polyanthum. J Nat Prod. 2004;67:1598-600 pubmed
    ..diastereoisomers, calopolyanolides C (1) and D (2), were isolated from the ethanolic extract of the seeds of Calophyllum polyanthum, along with calopolyanolide A (3), calopolyanolide B (4), calanolide E2 (5), 5,7,3',4'-..
  2. Yimdjo M, Azebaze A, Nkengfack A, Meyer A, Bodo B, Fomum Z. Antimicrobial and cytotoxic agents from Calophyllum inophyllum. Phytochemistry. 2004;65:2789-95 pubmed
    The study of the chemical constituents of the root bark and the nut of Calophyllum inophyllum has resulted in the isolation and characterization of a xanthone derivative, named inoxanthone, 3, together with 12 known compounds: ..
  3. da Silva K, dos Santos A, Mattos P, Yunes R, Delle Monache F, Cechinel Filho V. Chemical composition and analgesic activity of Calophyllum brasiliense leaves. Therapie. 2001;56:431-4 pubmed
    This paper describes a phytochemical and pharmacological study with Calophyllum brasiliense leaves, a medicinal plant employed in folk medicine for the treatment of several ailments...
  4. Dharmaratne H, Tan G, Marasinghe G, Pezzuto J. Inhibition of HIV-1 reverse transcriptase and HIV-1 replication by Calophyllum coumarins and xanthones. Planta Med. 2002;68:86-7 pubmed
    As part of our continuing study on the Calophyllum species, a number of coumarins, xanthones and chromene acids from different Calophyllum species of Sri Lanka were tested for inhibitory activity against the HIV-1 and its virally-encoded ..
  5. Oger J, Morel C, Helesbeux J, Litaudon M, Seraphin D, Dartiguelongue C, et al. First 2-hydroxy-3-methylbut-3-enyl substituted xanthones isolated from plants: structure elucidation, synthesis and antifungal activity. Nat Prod Res. 2003;17:195-9 pubmed
    ..xanthones, (+/-)-caledol 1 and (+/-)-dicaledol 2 were isolated from a dichloromethane extract of the leaves of Calophyllum caledonicum (Clusiaceae)...
  6. Brenzan M, Nakamura C, Prado Dias Filho B, Ueda Nakamura T, Young M, Aparício Garcia Cortez D. Antileishmanial activity of crude extract and coumarin from Calophyllum brasiliense leaves against Leishmania amazonensis. Parasitol Res. 2007;101:715-22 pubmed
    ..compound (-) mammea A/BB is a coumarin-type mammea purified from a dichloromethane crude extract of leaves of Calophyllum brasiliense Cambess (Clusiaceae)...
  7. Brenzan M, Santos A, Nakamura C, Filho B, Ueda Nakamura T, Young M, et al. Effects of (-) mammea A/BB isolated from Calophyllum brasiliense leaves and derivatives on mitochondrial membrane of Leishmania amazonensis. Phytomedicine. 2012;19:223-30 pubmed publisher
    ..synthetic (7) and derivatives of coumarin (-) mammea A/BB (3-6) isolated from the dichloromethane extract of Calophyllum brasiliense leaves...
  8. Ito C, Itoigawa M, Mishina Y, Filho V, Mukainaka T, Tokuda H, et al. Chemical constituents of Calophyllum brasiliensis: structure elucidation of seven new xanthones and their cancer chemopreventive activity. J Nat Prod. 2002;65:267-72 pubmed
    The first study of chemical constituents of the stem bark of Calophyllum brasilienses collected in Brazil has led to the isolation and identification of seven new xanthones named brasixanthones A (1), B (4), C (5), D (6), E (2), F (3), ..
  9. Honda P, Ferreira I, Cortez D, Amado C, Silveira T, Brenzan M, et al. Efficacy of components from leaves of Calophyllum brasiliense against Leishmania (Leishmania) amazonensis. Phytomedicine. 2010;17:333-8 pubmed publisher
    Leishmanicide potential of Calophyllum brasiliense leaves on promastigote and amastigote of Leishmania (Leishmania) amazonensis is evaluated...

More Information

Publications84

  1. Hieu T, Kim S, Lee S, Ahn Y. Repellency to Stomoxys calcitrans (Diptera: Muscidae) of plant essential oils alone or in combination with Calophyllum inophyllum nut oil. J Med Entomol. 2010;47:575-80 pubmed
    ..Diptera: Muscidae) of 21 essential oils (EOs) alone or in combination with Calophyllum inophyllum L. (Clusiaceae) nut oil (tamanu oil) was examined using an exposed human hand bioassay...
  2. Reyes Chilpa R, Baggio C, Alavez Solano D, Estrada Muñiz E, Kauffman F, Sanchez R, et al. Inhibition of gastric H+,K+-ATPase activity by flavonoids, coumarins and xanthones isolated from Mexican medicinal plants. J Ethnopharmacol. 2006;105:167-72 pubmed
    ..four natural xanthones, an acetylated derivative, two coumarins (mammea A/BA and mammea C/OA) isolated from Calophyllum brasiliense Cambess and two flavonoids (minimiflorin and mundulin) isolated from Lonchocarpus oaxacensis ..
  3. Reyes Chilpa R, Estrada Muñiz E, Apan T, Amekraz B, Aumelas A, Jankowski C, et al. Cytotoxic effects of mammea type coumarins from Calophyllum brasiliense. Life Sci. 2004;75:1635-47 pubmed
    b>Calophyllum brasiliense (Clusiaceae) is a big tree from the Tropical Rain Forests of the American continent...
  4. Mah S, Ee G, Teh S, Rahmani M, Lim Y, Go R. Phylattrin, a new cytotoxic xanthone from Calophyllum soulattri. Molecules. 2012;17:8303-11 pubmed publisher
    Our continuing studies on secondary metabolites from the stem bark of Calophyllum soulattri has led to the isolation of another new diprenylated xanthone, phylattrin (1), in addition to five other xanthones and two common sterols...
  5. Cechinel Filho V, Meyre Silva C, Niero R. Chemical and pharmacological aspects of the genus Calophyllum. Chem Biodivers. 2009;6:313-27 pubmed publisher
    The Calophyllum genus (Clusiaceae) is composed of ca. 200 species, with a pantropical distribution...
  6. Hieu T, Kim S, Kwon H, Ahn Y. Enhanced repellency of binary mixtures of Zanthoxylum piperitum pericarp steam distillate or Zanthoxylum armatum seed oil constituents and Calophyllum inophyllum nut oil and their aerosols to Stomoxys calcitrans. Pest Manag Sci. 2010;66:1191-8 pubmed publisher
    ..distillate (ZP-SD), Zanthoxylum armatum DC seed oil (ZA-SO) and their constituents alone or in combination with Calophyllum inophyllum L...
  7. SathyaSelvabala V, Selvaraj D, Kalimuthu J, Periyaraman P, Subramanian S. Two-step biodiesel production from Calophyllum inophyllum oil: optimization of modified ?-zeolite catalyzed pre-treatment. Bioresour Technol. 2011;102:1066-72 pubmed publisher
    In this study, a two-step process was developed to produce biodiesel from Calophyllum inophyllum oil...
  8. Ee G, Mah S, Teh S, Rahmani M, Go R, Taufiq Yap Y. Soulamarin, a new coumarin from stem bark of Calophyllum soulattri. Molecules. 2011;16:9721-7 pubmed publisher
    The extracts of the stem bark of Calophyllum soulattri gave a new pyranocoumarin, soulamarin (1), together with five other xanthones caloxanthone B (2), caloxanthone C (3), macluraxanthone (4), trapezifolixanthone (5) and brasixanthone B ..
  9. Hay A, Helesbeux J, Duval O, Labaïed M, Grellier P, Richomme P. Antimalarial xanthones from Calophyllum caledonicum and Garcinia vieillardii. Life Sci. 2004;75:3077-85 pubmed
    ..4), dombakinaxanthone (5), macluraxanthone (6), and 6-deoxy-gamma-mangostin (7) were isolated from Calophyllum caledonicum...
  10. Kimura S, Ito C, Jyoko N, Segawa H, Kuroda J, Okada M, et al. Inhibition of leukemic cell growth by a novel anti-cancer drug (GUT-70) from calophyllum brasiliense that acts by induction of apoptosis. Int J Cancer. 2005;113:158-65 pubmed
    ..derived from plant sources, we discovered that the natural product GUT-70, isolated from the stem bark of Calophyllum brasiliense collected in Brazil, significantly inhibits the growth of leukemic cells...
  11. Zou J, Jin D, Chen W, Wang J, Liu Q, Zhu X, et al. Selective cyclooxygenase-2 inhibitors from Calophyllum membranaceum. J Nat Prod. 2005;68:1514-8 pubmed
    Chemical investigation of the anti-inflammatory Chinese folk medicine Calophyllum membranaceum has resulted in the isolation and characterization of three new xanthones (1-3), one new biphenyl C-glycoside (4), and one new phenylethanoid ..
  12. Cottiglia F, Dhanapal B, Sticher O, Heilmann J. New chromanone acids with antibacterial activity from Calophyllum brasiliense. J Nat Prod. 2004;67:537-41 pubmed
    Six novel chromanone acids (1-6) were isolated from the bark of Calophyllum brasiliense Cambess. Their structures were elucidated on the basis of 1D and 2D NMR experiments, as well as mass spectrometry...
  13. Gonçalves R, Lemos C, Leal I, Nakamura C, Cortez D, da Silva E, et al. Comparing conventional and supercritical extraction of (-)-mammea A/BB and the antioxidant activity of Calophyllum brasiliense extracts. Molecules. 2013;18:6215-29 pubmed publisher
    b>Calophyllum brasiliense is a rich source of bioactive coumarins, xanthones and biflavonoids. The aim of the study was to compare the phenol contents and the antioxidant activity of C...
  14. Blanco Ayala T, Lugo Huitrón R, Serrano López E, Reyes Chilpa R, Rangel López E, Pineda B, et al. Antioxidant properties of xanthones from Calophyllum brasiliense: prevention of oxidative damage induced by FeSO?. BMC Complement Altern Med. 2013;13:262 pubmed publisher
    ..The present study tested the protective effect of two xanthones isolated from the heartwood of Calophyllum brasilienses against FeSO?-induced toxicity...
  15. Liu W, Liu Y, Chen Z, Chiou W, Tsai Y, Chen C. Calophyllolide content in Calophyllum inophyllum at different stages of maturity and its osteogenic activity. Molecules. 2015;20:12314-27 pubmed publisher
    b>Calophyllum inophyllum is a coastal plant rich in natural substances. Its ingredients have been used for the development of an anti-human immunodeficiency virus (HIV) drug. In this study, we collected C...
  16. Dharmaratne H, Napagoda M, Tennakoon S. Xanthones from roots of Calophyllum thwaitesii and their bioactivity. Nat Prod Res. 2009;23:539-45 pubmed publisher
    Extracts from three Calophyllum species endemic to Sri Lanka were tested for antifungal and antioxidant activities...
  17. Ming M, Zhang X, Chen H, Zhu L, Zeng D, Yang J, et al. RXRα transcriptional inhibitors from the stems of Calophyllum membranaceum. Fitoterapia. 2016;108:66-72 pubmed publisher
    Bioassay-guided fractionation of the 60% ethanol extract of the stems of Calophyllum membranaceum using the RXRα transcription activation assay led to the isolation of two new chromanones, calopolyanic acid methyl ester (1) and ..
  18. Klein Júnior L, Zambiasi D, Salgado G, Delle Monache F, Filho V, de Campos Buzzi F. The validation of Calophyllum brasiliense ("guanandi") uses in Brazilian traditional medicine as analgesic by in vivo antinociceptive evaluation and its chemical analysis. Naunyn Schmiedebergs Arch Pharmacol. 2017;390:733-739 pubmed publisher
    b>Calophyllum brasiliense is used as anti-inflammatory and analgesic in Brazilian traditional medicine. Thus, the main purpose of this study is to evaluate the antinociceptive effect of the chloroform fraction of C...
  19. Raad I, Terreux R, Richomme P, Matera E, Dumontet C, Raynaud J, et al. Structure-activity relationship of natural and synthetic coumarins inhibiting the multidrug transporter P-glycoprotein. Bioorg Med Chem. 2006;14:6979-87 pubmed
    ..Four natural compounds, previously isolated from Calophyllum dispar (Clusiaceae) and substituted by a common alpha-(hydroxyisopropyl)dihydrofuran moiety, exhibited a ..
  20. Ferchichi L, Derbré S, Mahmood K, Touré K, Guilet D, Litaudon M, et al. Bioguided fractionation and isolation of natural inhibitors of advanced glycation end-products (AGEs) from Calophyllum flavoramulum. Phytochemistry. 2012;78:98-106 pubmed publisher
    ..b>Calophyllum flavoramulum Hend. & Wyatt-Sm...
  21. Hay A, Guilet D, Morel C, Larcher G, Macherel D, Le Ray A, et al. Antifungal chromans inhibiting the mitochondrial respiratory chain of pea seeds and new xanthones from Calophyllum caledonicum. Planta Med. 2003;69:1130-5 pubmed
    ..L 2, and one new acid, caledonic acid 6 were isolated from the hexane-soluble extract of the stem bark of Calophyllum caledonicum...
  22. Wei D, Mei W, Zhong H, Zeng Y, Wu X, Dai H. A new prenylated xanthone from the branches of Calophyllum inophyllum. J Asian Nat Prod Res. 2011;13:265-9 pubmed publisher
    The investigation of chemical constituents from the branches of Calophyllum inophyllum Linn led to the isolation of a new prenylated xanthone, named caloxanthone Q (1), together with three known compounds, 2-deprenylrheediaxanthone B (2),..
  23. Prasad J, Maurya C, Pandey J, Jaiswal N, Madhur G, Srivastava A, et al. Diastereomeric mixture of calophyllic acid and isocalophyllic acid stimulates glucose uptake in skeletal muscle cells: involvement of PI-3-kinase- and ERK1/2-dependent pathways. Mol Cell Endocrinol. 2013;370:11-9 pubmed publisher
    The diastereomeric mixture of calophyllic acid and isocalophyllic acid (F015) isolated from the leaves of Calophyllum inophyllum was investigated for the metabolic effect on glucose transport in skeletal muscle cells...
  24. Gómez Robledo H, Cruz Sosa F, Bernabé Antonio A, Guerrero Analco A, Olivares Romero J, Alonso Sánchez A, et al. Identification of candidate genes related to calanolide biosynthesis by transcriptome sequencing of Calophyllum brasiliense (Calophyllaceae). BMC Plant Biol. 2016;16:177 pubmed publisher
    b>Calophyllum brasiliense is highlighted as an important resource of calanolides, which are dipyranocoumarins that inhibit the reverse transcriptase of human immunodeficiency virus type 1 (HIV-1 RT)...
  25. Lemos L, Miyajima F, Castilho G, Martins D, Pritchard D, Burkitt M. Hexane Extracts of Calophyllum brasiliense Inhibit the Development of Gastric Preneoplasia in Helicobacter felis Infected INS-Gas Mice. Front Pharmacol. 2017;8:92 pubmed publisher
    b>Objectives: Indigenous Latin American populations have used extracts from Calophyllum brasiliense, a native hardwood, to treat gastrointestinal symptoms for generations...
  26. Ruan J, Zheng C, Liu Y, Qu L, Yu H, Han L, et al. Chemical and Biological Research on Herbal Medicines Rich in Xanthones. Molecules. 2017;22: pubmed publisher
    ..Among them, Calophyllum, Cratoxylum, Cudrania, Garcinia, Gentiana, Hypericum and Swertia ..
  27. Li Y, Li Z, Yin S, Shi G, Liu M, Jing Y, et al. Triterpenoids from Calophyllum inophyllum and their growth inhibitory effects on human leukemia HL-60 cells. Fitoterapia. 2010;81:586-9 pubmed publisher
    ..friedelane-type triterpene (1), along with seven known triterpenoids, was isolated from the stems and leaves of Calophyllum inophyllum Linn...
  28. Tsai S, Liang Y, Chiang J, Liu F, Lin W, Chang S, et al. Anti-inflammatory effects of Calophyllum inophyllum L. in RAW264.7 cells. Oncol Rep. 2012;28:1096-102 pubmed publisher
    b>Calophyllum inophyllum L. has been used as folk medicine in the treatment of ocular burn and it has demonstrated potential to be an anti-inflammatory agent...
  29. Oku H, Ueda Y, Iinuma M, Ishiguro K. Inhibitory effects of xanthones from guttiferae plants on PAF-induced hypotension in mice. Planta Med. 2005;71:90-2 pubmed
    The inhibitory effects of 22 xanthones from three Guttiferae plants (Hypericum patulum, Calophyllum inophyllum and C...
  30. Monirul I, Masjuki H, Kalam M, Zulkifli N, Shancita I. Influence of polymethyl acrylate additive on the formation of particulate matter and NOX emission of a biodiesel-diesel-fueled engine. Environ Sci Pollut Res Int. 2017;24:18479-18493 pubmed publisher
    ..formation of particulate matter (PM) and nitrogen oxide (NOX) emission from a diesel coconut and/or Calophyllum inophyllum biodiesel-fueled engine. The physicochemical properties of 20% of coconut and/or C...
  31. Souza M, Beserra A, Martins D, Real V, Santos R, Rao V, et al. In vitro and in vivo anti-Helicobacter pylori activity of Calophyllum brasiliense Camb. J Ethnopharmacol. 2009;123:452-8 pubmed publisher
    b>Calophyllum brasiliense (Camb.) is a medicinal tree that grows particularly in the hilly and forested regions of Brazil. Preparations from its stem bark are popular remedies for the treatment of chronic ulcers...
  32. Rajamohan S, Kasimani R. Analytical characterization of products obtained from slow pyrolysis of Calophyllum inophyllum seed cake: study on performance and emission characteristics of direct injection diesel engine fuelled with bio-oil blends. Environ Sci Pollut Res Int. 2018;25:9523-9538 pubmed publisher
    ..the characteristics and properties of the fractions obtained from slow pyrolysis of non-edible seed cake of Calophyllum inophyllum (CI)...
  33. Le Coz C. Allergic contact dermatitis from tamanu oil (Calophyllum inophyllum, Calophyllum tacamahaca). Contact Dermatitis. 2004;51:216-7 pubmed
  34. Ee G, Mah S, Rahmani M, Taufiq Yap Y, Teh S, Lim Y. A new furanoxanthone from the stem bark of Calophyllum inophyllum. J Asian Nat Prod Res. 2011;13:956-60 pubmed publisher
    The stem bark extracts of Calophyllum inophyllum furnished one new furanoxanthone, inophinnin (1), in addition to inophyllin A (2), macluraxanthone (3), pyranojacareubin (4), 4-hydroxyxanthone, friedelin, stigmasterol, and betulinic acid...
  35. Alagu R, Sundaram E, Natarajan E. Thermal and catalytic slow pyrolysis of Calophyllum inophyllum fruit shell. Bioresour Technol. 2015;193:463-8 pubmed publisher
    Pyrolysis of Calophyllum inophyllum shell was performed in a fixed bed pyrolyser to produce pyrolytic oil...
  36. Silveira S, Cordeiro Silva R, Degenhardt Goldbach J, Quoirin M. Micropropagation of Calophyllum brasiliense (Cambess.) from nodal segments. Braz J Biol. 2016;76:656-63 pubmed publisher
    Micropropagation of Calophyllum brasiliense Cambess...
  37. Shen Y, Hung M, Wang L, Chen C. Inocalophyllins A, B and their methyl esters from the seeds of Calophyllum inophyllum. Chem Pharm Bull (Tokyo). 2003;51:802-6 pubmed
    Fractionation of the ethanolic extract of the seeds of Calophyllum inophyllum L...
  38. Leu T, Raharivelomanana P, Soulet S, Bianchini J, Herbette G, Faure R. New tricyclic and tetracyclic pyranocoumarins with an unprecedented C-4 substituent. Structure elucidation of tamanolide, tamanolide D and tamanolide P from Calophyllum inophyllum of French Polynesia. Magn Reson Chem. 2009;47:989-93 pubmed publisher
    ..derivatives, tamanolide (1), tamanolide D (2) and tamanolide P (3), were isolated from the almond seeds of Calophyllum inophyllum L. (Clusiaceae) grown in French Polynesia...
  39. Piccinelli A, Kabani A, Lotti C, Alarcón A, Cuesta Rubio O, Rastrelli L. A fast and efficient HPLC-PDA-MS method for detection and identification of pyranochromanone acids in Calophyllum species. J Pharm Biomed Anal. 2013;76:157-63 pubmed publisher
    Pyranochromanone acids isolated from Calophyllum species have shown a variety of biological potentialities including antioxidant, antiulcer, anticancer and anti-Helicobacter pylori activities...
  40. Brenzan M, Nakamura C, Dias Filho B, Ueda Nakamura T, Young M, Côrrea A, et al. Structure-activity relationship of (-) mammea A/BB derivatives against Leishmania amazonensis. Biomed Pharmacother. 2008;62:651-8 pubmed publisher
    To study the structure-activity relationship of coumarin (-) mammea A/BB isolated from the CH(2)Cl(2) extract of Calophyllum brasiliense leaves, we evaluated the antileishmanial activity of natural, synthetic and derivatives of this ..
  41. Cao S, Low K, Glover R, Crasta S, Ng S, Buss A, et al. Sundaicumones A and B, polyprenylated acylphloroglucinol derivatives from Calophyllumsundaicum with weak activity against the glucocorticoid receptor. J Nat Prod. 2006;69:707-9 pubmed
    ..weakly active polyprenylated acylphloroglucinol derivatives, sundaicumones A (1) and B (2), from the leaves of Calophyllum sundaicum collected in Singapore...
  42. Taher M, Idris M, Ahmad F, Arbain D. A polyisoprenylated ketone from Calophyllum enervosum. Phytochemistry. 2005;66:723-6 pubmed
    A polyisoprenylated ketone named enervosanone has been isolated from the stem bark of Calophyllum enervosum together with three known compounds, cambogin, osajaxanthone and epicatechin...
  43. Li Z, Liu D, Li D, Hua H. A novel prenylated xanthone from the stems and leaves of Calophyllum inophyllum. Nat Prod Res. 2011;25:905-8 pubmed publisher
    A novel prenylated xanthone, caloxanthone Q, was isolated from the stems and leaves of Calophyllum inophyllum. The structure elucidation was carried out by detailed spectroscopic analysis.
  44. Luo H, Guo Y, Cui T, Dai J, Zhang J, Xu B. [Effects of fungal elicitor on inophyllums production in suspension cultured cells of Calophyllum inophyllum L]. Yao Xue Xue Bao. 2004;39:305-8 pubmed
    To investigate the effects of fungal elicitors on inophyllums production in suspension cultured cell of Calophyllum inophyllum Linn.
  45. Ito C, Itoigawa M, Mishina Y, Filho V, Enjo F, Tokuda H, et al. Chemical constituents of Calophyllum brasiliense. 2. Structure of three new coumarins and cancer chemopreventive activity of 4-substituted coumarins. J Nat Prod. 2003;66:368-71 pubmed
    ..our search for cancer chemopreventive agents from natural sources, we examined constituents of the stem bark of Calophyllum brasiliense...
  46. Caneppele D, Vieira P, Dall Oglio E, da Silva L, Sousa P. Unequivocal NMR assignments: O-methoxy-methyl esters derivatives of acid chromanones from Calophyllum brasiliense CAMB. (Guanandi). Nat Prod Res. 2008;22:846-53 pubmed publisher
    The present work describes the fractionation of the crude hexane extract (EBHEX) from Calophyllum brasiliense (Clusiaceae) stem bark...
  47. Khan M, Kihara M, Omoloso A. Antimicrobial activity of Calophyllum soulattri. Fitoterapia. 2002;73:741-3 pubmed
    The methanol extracts of leaves, root and stem barks of Calophyllum soulattri were partitioned with petrol, dichloromethane, ethyl acetate. The extracts demonstrated a range of antibacterial activity, improved on fractionation...
  48. Isaias D, Niero R, Noldin V, De Campos Buzzi F, Yunes R, Delle Monache F, et al. Pharmacological and phytochemical investigations of different parts of Calophyllum brasiliense (Clusiaceae). Pharmazie. 2004;59:879-81 pubmed
    ..the antinociceptive effects of some fractions obtained from different parts (roots, flowers and fruits) of Calophyllum brasiliense, a Brazilian medicinal plant used to treat several diseases, including inflammation and pain...
  49. Setsuko S, Uchiyama K, Sugai K, Hanaoka S, Yoshimaru H. Microsatellite markers derived from Calophyllum inophyllum (Clusiaceae) expressed sequence tags. Am J Bot. 2012;99:e28-32 pubmed publisher
    Robust markers are required (inter alia) for assessing origins of Calophyllum inophyllum populations on the Bonin Islands, Japan...
  50. Ruiz Marcial C, Reyes Chilpa R, Estrada E, Reyes Esparza J, Fariña G, Rodriguez Fragoso L. Antiproliferative, cytotoxic and antitumour activity of coumarins isolated from Calophyllum brasiliense. J Pharm Pharmacol. 2007;59:719-25 pubmed
    Among the eight Calophyllum species found on the American continent, Calophyllum brasiliense is the most widely distributed...
  51. Shen Y, Wang L, Khalil A, Chiang L, Cheng P. Bioactive pyranoxanthones from the roots of Calophyllum blancoi. Chem Pharm Bull (Tokyo). 2005;53:244-7 pubmed
    Phytochemical investigation of the roots of Calophyllum blancoi growing in Taiwan resulted in the isolation of three new pyranoxanthones, blancoxanthone (1), acetyl blancoxanthone (2) and 3-hydroxyblancoxanthone (3), in addition to two ..
  52. Zhong H, Ruan J, Yao Q. Two new 4-arylcoumarins from the seeds of Calophyllum polyanthum. J Asian Nat Prod Res. 2010;12:562-8 pubmed publisher
    ..2), together with four known compounds were isolated from the seeds of Calophyllum polyanthum...
  53. Dai H, Zeng Y, Xiao Q, Han Z, Zhao Y, Mei W. Caloxanthones O and P: two new prenylated xanthones from Calophyllum inophyllum. Molecules. 2010;15:606-12 pubmed publisher
    Chemical investigation of the EtOH extract of the twigs of Calophyllum inophyllum collected in Hainan Province of China resulted in the isolation of two new prenylated xanthones, caloxanthone O (1) and caloxanthone P (2)...
  54. Dharmaratne H, Marasinghe G. New methylethers of cordatolides from Calophyllum cordato-oblongum and their synthesis. Nat Prod Res. 2009;23:883-90 pubmed publisher
    Twigs of Calophyllum cordato-oblongum Thw. have been shown to contain cordatolide A-OMe, cordatolide B-OMe, cordatolide C-OMe, cordatolide A, cordatolide B, oblongulide, cordatooblongic acid, friedelin, canophyllol, and sitosterol...
  55. Huerta Reyes M, Basualdo M, Abe F, Jimenez Estrada M, Soler C, Reyes Chilpa R. HIV-1 inhibitory compounds from Calophyllum brasiliense leaves. Biol Pharm Bull. 2004;27:1471-5 pubmed
    The hexane, acetone and methanol extracts of Calophyllum brasiliense leaves were fractionated following a three bioassay guide: high HIV-1 RT inhibition, low cytotoxicity on MT2 cells and high inhibition of HIV-1 IIIb/LAV replication...
  56. Nguyen V, Truong C, Nguyen B, Vo T, Dao T, Nguyen V, et al. Anti-inflammatory and wound healing activities of calophyllolide isolated from Calophyllum inophyllum Linn. PLoS ONE. 2017;12:e0185674 pubmed publisher
    ..report anti-inflammatory and wound healing activities of the major calophyllolide (CP) compound isolated from Calophyllum inophyllum Linn...
  57. Prasad J, Shrivastava A, Khanna A, Bhatia G, Awasthi S, Narender T. Antidyslipidemic and antioxidant activity of the constituents isolated from the leaves of Calophyllum inophyllum. Phytomedicine. 2012;19:1245-9 pubmed publisher
    ..our drug discovery program on Indian medicinal plants, we isolated bioactive compounds (1-5) from the leaves of Calophyllum inophyllum and evaluated their antidyslipidemic activity in triton induced hyperlipidemia model...
  58. Braga F, Serra C, Viana N, Oliveira A, Cortes S, Lombardi J. Angiotensin-converting enzyme inhibition by Brazilian plants. Fitoterapia. 2007;78:353-8 pubmed
    ..The following plants presented significant ACE inhibition rates: Calophyllum brasiliense, Combretum fruticosum, Leea rubra, Phoenix roebelinii and Terminalia catappa.
  59. Ee G, Ng K, Taufiq Yap Y, Rahmani M, Ali A, Muse R. Mucigerin, a new coumarin from Calophyllum mucigerum (Guttiferae). Nat Prod Res. 2004;18:123-8 pubmed
    Our recent studies on the stem bark of Calophyllum mucigerum (Guttiferae) have yielded a new coumarin mucigerin, a prenylated xanthone cudraxanthone C and the common steroidal triterpenes friedelin and stigmasterol...
  60. Said T, Dutot M, Martin C, Beaudeux J, Boucher C, Enee E, et al. Cytoprotective effect against UV-induced DNA damage and oxidative stress: role of new biological UV filter. Eur J Pharm Sci. 2007;30:203-10 pubmed
    ..Because most UV filters are cytotoxic for the eye, we investigated the anti-UV properties of Calophyllum inophyllum oil in order to propose it as a potential vehicle, free of toxicity, with a natural UV filter action ..
  61. Chaturvedi N, Dhal N, Reddy P. Phytostabilization of iron ore tailings through Calophyllum inophyllum L. Int J Phytoremediation. 2012;14:996-1009 pubmed
    The phytostabilization of waste material generated during mining and processing of iron ore through Calophyllum inophyllum L. have been investigated...
  62. Ee G, Kua A, Lim C, Jong V, Lee H. Inophyllin A, a new pyranoxanthone from Calophyllum inophyllum (Guttiferae). Nat Prod Res. 2006;20:485-91 pubmed
    In the authors' continuing search for new natural products, their recent studies on the roots of Calophyllum inophyllum (Guttiferae) have yielded a new prenylated pyranoxanthone, Inophyllin A together with the common triterpenes ..
  63. Lamba N, Gupta K, Modak J, Madras G. Biodiesel synthesis from Calophyllum inophyllum oil with different supercritical fluids. Bioresour Technol. 2017;241:767-774 pubmed publisher
    ..However, in the present study, FAMEs were synthesized from a non-edible oil (Calophyllum inophyllum also called as sura honne, Punnagam, Alexandrian Laurel) in different supercritical fluids: methanol ..
  64. Krause G, Grube E, Virgo A, Winter K. Sudden exposure to solar UV-B radiation reduces net CO(2) uptake and photosystem I efficiency in shade-acclimated tropical tree seedlings. Plant Physiol. 2003;131:745-52 pubmed
    ..of photosynthesis in leaves of shade-acclimated seedlings (Anacardium excelsum, Virola surinamensis, and Calophyllum longifolium) to exposure to direct sunlight (for 20-50 min) was investigated in Panama (9 degrees N)...
  65. Sakagami Y, Kajimura K, Wijesinghe W, Dharmaratne H. Antibacterial activity of calozeyloxanthone isolated from Calophyllum species against vancomycin-resistant Enterococci (VRE) and synergism with antibiotics. Planta Med. 2002;68:541-3 pubmed
    Calozeyloxanthone ( 1) was re-isolated from the root bark of Calophyllum moonii, an endemic species of Sri Lanka, and found to be active against vancomycin-resistant Enterococci (VRE) and vancomycin-sensitive Enterococci (VSE) with MIC ..
  66. Nguyen L, Nguyen D, Nguyen L. A new xanthone from the bark of Calophyllum thorelii. Nat Prod Res. 2013;27:563-7 pubmed publisher
    ..1,7-dihydroxyxanthone and globuxanthone, was isolated from a petroleum ether extract of the bark of Calophyllum thorelii...
  67. Gomez Verjan J, Estrella Parra E, Vazquez Martinez E, González Sánchez I, Guerrero Magos G, Mendoza Villanueva D, et al. Risk assessment of Soulatrolide and Mammea (A/BA+A/BB) coumarins from Calophyllum brasiliense by a toxicogenomic and toxicological approach. Food Chem Toxicol. 2016;91:117-29 pubmed publisher
    b>Calophyllum brasiliense (Calophyllaceae) is a tropical rain forest tree distributed in Central and South America. It is an important source of tetracyclic dipyrano coumarins (Soulatrolide) and Mammea type coumarins...
  68. Joshi S, Kulkarni S, Phalgune U, Puranik V. New dipyranocoumarin from the leaves of Calophyllum apetalum Willd. Nat Prod Res. 2013;27:1896-901 pubmed publisher
    A new dipyranocoumarin, ?-hydroxytomentolide A (1) was isolated from the leaves of Calophyllum apetalum together with the known compounds friedelin (2), apetalactone (3), inophyllum C (4) and canophyllol (5)...
  69. Pretto J, Cechinel Filho V, Noldin V, Sartori M, Isaias D, Cruz A. Antimicrobial activity of fractions and compounds from Calophyllumbrasiliense (Clusiaceae/Guttiferae). Z Naturforsch C. 2004;59:657-62 pubmed
    b>Calophyllum brasiliense (Clusiaceae/Guttiferae) is a native Brazilian medicinal plant traditionally used against several diseases, including infectious pathologies...
  70. Lemos L, Martins T, Tanajura G, Gazoni V, Bonaldo J, Strada C, et al. Evaluation of antiulcer activity of chromanone fraction from Calophyllum brasiliesnse Camb. J Ethnopharmacol. 2012;141:432-9 pubmed publisher
    b>Calophyllum brasiliense Camb. (Clusiaceae), popularly known as 'guanandi', is found in the tropical areas and swampy lands. The latex exuding from its bark is used in the treatment of gastric ulcer in folk medicine...
  71. Nasir N, Rahmani M, Shaari K, Ee G, Go R, Kassim N, et al. Two new xanthones from Calophyllum nodusum (Guttiferae). Molecules. 2011;16:8973-80 pubmed publisher
    The air-dried powdered stem bark of Calophyllum nodusum (Guttiferea) collected from Sandakan (Sabah, Malaysia), was extracted sequentially with hexane, chloroform and methanol...
  72. Wang H, Wang Y, Li J, Chen L. [Research progress of chromanone derivatives from Calophyllum]. Zhongguo Zhong Yao Za Zhi. 2011;36:1115-21 pubmed
    b>Calophyllum plants have great pharmaceutical value. Some species of this genus are used in folk medicine to treat and cure diseases, such as toothache, rheumatism, diarrhea, chronic ulcers, skin infections, and wounds...
  73. Krause G, Galle A, Virgo A, Garcia M, Bucic P, Jahns P, et al. High-light stress does not impair biomass accumulation of sun-acclimated tropical tree seedlings (Calophyllum longifolium Willd. and Tectona grandis L. f.). Plant Biol (Stuttg). 2006;8:31-41 pubmed
    Studies with seedlings of tropical rainforest trees ( Calophyllum longifolium Willd.; Tectona grandis L. f.) were designed to test whether high-light stress affects photosynthetic performance and growth...
  74. Ito C, Murata T, Itoigawa M, Nakao K, Kaneda N, Furukawa H. Apoptosis inducing activity of 4-substituted coumarins from Calophyllum brasiliense in human leukaemia HL-60 cells. J Pharm Pharmacol. 2006;58:975-80 pubmed
    ..anti-tumour-promoting agents, we carried out a primary screening of ten 4-substituted coumarins isolated from Calophyllum brasiliense Camb...
  75. Helesbeux J, Seraphin D, Duval O, Richomme P, Bruneton J. Studies on the reactivity of a tertiary allylic alcohol in an acetophenonic series, a model for natural products synthesis. J Pharm Pharmacol. 2001;53:955-8 pubmed
    ..These natural products have anti-cancer activity. The 1,3-diacetoxy-2-acetyl-4-(3-hydroxy-3-methylbut-1-enyl)benzene synthone is used as a common precursor to these structures...