smilax

Summary

Summary: A plant genus of the family SMILACACEAE. Members contain smiglasides (phenylpropanoid glycosides) and steroidal saponins. Commercially it is sometimes adulterated with HEMIDESMUS, which would affect experimental results. Drinks called sarsaparilla and root beer have been prepared from the Smilaz ornata (Jamaican sarsaparilla) and SASSAFRAS.

Top Publications

  1. Wu L, Wang X, Wang H, Yang H, Jia A, Ding Q. Cytotoxic polyphenols against breast tumor cell in Smilax china L. J Ethnopharmacol. 2010;130:460-4 pubmed
    b>Smilax china L., referred to 'Ba Qia' (or 'Jin Gang Teng') in China, is a small vine that grows in the southern parts of China. The roots and tubers of S. china L...
  2. Xu S, Shang M, Liu G, Xu F, Wang X, Shou C, et al. Chemical constituents from the rhizomes of Smilax glabra and their antimicrobial activity. Molecules. 2013;18:5265-87 pubmed publisher
    ..4), smiglactone (5), smiglabrol (6), together with fifty-seven known ones 7-63 were isolated from the rhizomes of Smilax glabra...
  3. Jiang J, Xu Q. Immunomodulatory activity of the aqueous extract from rhizome of Smilax glabra in the later phase of adjuvant-induced arthritis in rats. J Ethnopharmacol. 2003;85:53-9 pubmed
    ..Such characteristics of RSG on AA may be advantageous to the long-term treatment of clinical rheumatoid arthritis...
  4. Xu J, Li X, Zhang P, Li Z, Wang Y. Antiinflammatory constituents from the roots of Smilax bockii warb. Arch Pharm Res. 2005;28:395-9 pubmed
    From 70% ethanol extract of the roots of Smilax bockii warb...
  5. Shu X, Gao Z, Yang X. Anti-inflammatory and anti-nociceptive activities of Smilax china L. aqueous extract. J Ethnopharmacol. 2006;103:327-32 pubmed
    The aqueous extract of the tuber of Smilax china L...
  6. Sa F, Gao J, Fung K, Zheng Y, Lee S, Wang Y. Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines. Chem Biol Interact. 2008;171:1-14 pubmed
    b>Smilax glabra Roxb. (SGR) is the root of a traditional Chinese herb, referred to as tu fu ling in Chinese medicine...
  7. Xu W, Liu J, Li C, Wu H, Liu Y. Kaempferol-7-O-beta-D-glucoside (KG) isolated from Smilax china L. rhizome induces G2/M phase arrest and apoptosis on HeLa cells in a p53-independent manner. Cancer Lett. 2008;264:229-40 pubmed publisher
    Kaempferol-7-O-beta-D-glucoside (KG), a flavonoid glycoside, isolated from Smilax china L...
  8. Xia D, Yu X, Liao S, Shao Q, Mou H, Ma W. Protective effect of Smilax glabra extract against lead-induced oxidative stress in rats. J Ethnopharmacol. 2010;130:414-20 pubmed publisher
    b>Smilax glabra Roxb. is a traditional Chinese herb, the rhizome of Smilax glabra has been used in folk medicine for the treatment of lead poisoning.
  9. Gao Y, Su Y, Qu L, Xu S, Meng L, Cai S, et al. Mitochondrial apoptosis contributes to the anti-cancer effect of Smilax glabra Roxb. Toxicol Lett. 2011;207:112-20 pubmed publisher
    b>Smilax glabra Roxb. (SGR), a member of the Smilacaceae family and a rhizome of the Liliaceae plant, has shown anti-inflammation and detoxification properties, and a few studies reported its anti-cancer effect...

More Information

Publications108 found, 100 shown here

  1. Thabrew M, Mitry R, Morsy M, Hughes R. Cytotoxic effects of a decoction of Nigella sativa, Hemidesmus indicus and Smilax glabra on human hepatoma HepG2 cells. Life Sci. 2005;77:1319-30 pubmed
    A decoction of Nigella sativa seeds, Hemidesmus indicus root and Smilax glabra rhizome is used by traditional medical practitioners in Sri Lanka to treat cancer and has been shown to prevent chemically induced carcinogenesis in rats...
  2. Ang H, Lee K, Kiyoshi M. Determination of lead in Smilax luzonensis herbal preparations in Malaysia. Int J Toxicol. 2005;24:165-71 pubmed
    ..As such, a total of 100 products in various pharmaceutical dosage forms of a herbal preparation containing Smilax luzonensis, either single or combined preparations, were analyzed for the presence of lead, using atomic ..
  3. Shao B, Guo H, Cui Y, Ye M, Han J, Guo D. Steroidal saponins from Smilax china and their anti-inflammatory activities. Phytochemistry. 2007;68:623-30 pubmed
    Steroidal saponins, 1, 2, 3 and 4, were isolated from the BuOH extract of Smilax china L., along with 13 known compounds, 5-17...
  4. Khan I, Nisar M, Ebad F, Nadeem S, Saeed M, Khan H, et al. Anti-inflammatory activities of Sieboldogenin from Smilax china Linn.: experimental and computational studies. J Ethnopharmacol. 2009;121:175-7 pubmed publisher
    b>Smilax china Linn. is extensively used in traditional Chinese medicine (TCM) as well as in Pakistan for several medicinal purposes including their use in inflammatory disorders.
  5. Ivanova A, Serly J, Dinchev D, Ocsovszki I, Kostova I, Molnar J. Screening of some saponins and phenolic components of Tribulus terrestris and Smilax excelsa as MDR modulators. In Vivo. 2009;23:545-50 pubmed
    ..Cytotoxic activity of saponins and phenolic compounds have been described in the literature, but no reports were found on their multidrug resistance (MDR)-modulating effects on human mdr1 gene-transfected mouse lymphoma cell line...
  6. Liu J, Qi Z, Zhao Y, Fu C, Jenny Xiang Q. Complete cpDNA genome sequence of Smilax china and phylogenetic placement of Liliales--influences of gene partitions and taxon sampling. Mol Phylogenet Evol. 2012;64:545-62 pubmed publisher
    The complete nucleotide sequence of the chloroplast genome (cpDNA) of Smilax china L. (Smilacaceae) is reported. It is the first complete cp genome sequence in Liliales...
  7. Xia D, Fan Y, Zhang P, Fu Y, Ju M, Zhang X. Protective effects of the flavonoid-rich fraction from rhizomes of Smilax glabra Roxb. on carbon tetrachloride-induced hepatotoxicity in rats. J Membr Biol. 2013;246:479-85 pubmed publisher
    ..The present study evaluated the protective effects of the flavonoid-rich fraction from rhizomes of Smilax glabra Roxb. (SGF) on carbon tetrachloride (CCl?)-induced hepatotoxicity in rats...
  8. Shao B, Guo H, Cui Y, Liu A, Yu H, Guo H, et al. Simultaneous determination of six major stilbenes and flavonoids in Smilax china by high performance liquid chromatography. J Pharm Biomed Anal. 2007;44:737-42 pubmed
    ..and specific HPLC method was developed for simultaneous determination of the six major active constituents in Smilax china, namely taxifolin-3-O-glycoside (1), piceid (2), oxyresveratrol (3), engeletin (4), resveratrol (5) and ..
  9. Li Y, Gan G, Zhang H, Wu H, Li C, Huang Y, et al. A flavonoid glycoside isolated from Smilax china L. rhizome in vitro anticancer effects on human cancer cell lines. J Ethnopharmacol. 2007;113:115-24 pubmed
    The anticancer activity of eight crude extracts of Smilax china L. rhizome (SCR) against HeLa cells was assessed by MTT assay and clonogenic assay, the fraction rich in flavonoids had show good activity against HeLa cells...
  10. Xu X, Wan Y, Qi Z, Qiu Y, Fu C. Isolation of compound microsatellite markers for the common Mediterranean shrub Smilax aspera (Smilacaceae). Am J Bot. 2011;98:e64-6 pubmed publisher
    Microsatellite markers were developed for the common Mediterranean shrub Smilax aspera to study the population genetics of this species.
  11. Seelinger M, Popescu R, Giessrigl B, Jarukamjorn K, Unger C, Wallnöfer B, et al. Methanol extract of the ethnopharmaceutical remedy Smilax spinosa exhibits anti-neoplastic activity. Int J Oncol. 2012;41:1164-72 pubmed publisher
    ..Therefore, extracts of the rhizome of Smilax spinosa, an ethnomedicinal plant from Guatemala which is used for the treatment of inflammatory conditions, were ..
  12. Chassagne F, Deharo E, Punley H, Bourdy G. Treatment and management of liver diseases by Khmer traditional healers practicing in Phnom Penh area, Cambodia. J Ethnopharmacol. 2017;202:38-53 pubmed publisher
    ..Among the plants reported, Cananga latifolia, Andrographis paniculata, Smilax aff. glabra, Gomphrena celosioides, Passiflora foetida and Physalis minima were the most cited species...
  13. Ooi L, Sun S, Wang H, Ooi V. New mannose-binding lectin isolated from the rhizome of Sarsaparilla Smilax glabra Roxb. (Liliaceae). J Agric Food Chem. 2004;52:6091-5 pubmed
    A new mannose-binding lectin, designated SGM2, was isolated from the rhizome of a Chinese medicinal herb Smilax glabra (also known as sarsaparilla in general) by saline extraction, ammonium sulfate precipitation and fractionation, and ..
  14. He X, Shun Q, Dong L, Ge X, Zhang H, Nong H, et al. [Comparison of anti-inflammatory effect and analysis of astilbin red and white transverse section Smilax glabra in 28 collection sites]. Zhongguo Zhong Yao Za Zhi. 2012;37:3595-8 pubmed
    Astilbin in 28 Smilax glabra (red and white cross-section) from different sources was determined by HPLC. Pharmacodynamics and component of S. glabra was investigated through inflammation experiment (penetration type)...
  15. Hao G, Zheng J, Huo R, Li J, Wen K, Zhang Y, et al. Smilax glabra Roxb targets Akt(p-Thr308) and inhibits Akt-mediated signaling pathways in SGC7901 cells. J Drug Target. 2016;24:557-65 pubmed publisher
    b>Smilax glabra Roxb (SGR) as a novel anti-tumor agent has been paid attention in several types of cancer cells. However, the effect of SGR on SGC7901 cells has not been investigated...
  16. Packer J, Naz T, Harrington D, Jamie J, Vemulpad S. Antimicrobial activity of customary medicinal plants of the Yaegl Aboriginal community of northern New South Wales, Australia: a preliminary study. BMC Res Notes. 2015;8:276 pubmed publisher
    ..scandens, Ipomoea brasiliensis, Lophostemon suaveolens and Syncarpia glomulifera and the aqueous extracts of Smilax australis and Smilax glyciphylla were tested against common wound pathogens, including antibiotic resistant ..
  17. Korn R. Tracheid analysis and modeling of the minor veins of the coleus and smilax leaves. Planta. 2006;224:915-23 pubmed
  18. Velasco Lezama R, Muñoz Torres A, Tapia Aguilar R, Flores Saenz J, Fregoso Padilla M, Vega Avila E, et al. Hematopoietic activity of Smilax aristolochiaefolia (zarzaparrilla) in mice with aplastic anemia. Proc West Pharmacol Soc. 2009;52:83-7 pubmed
    b>Smilax aristolochiaefolia (Liliaceae) has been used in Mexican traditional medicine for the treatment of tumors, leprosy, anemia and as a tonic for skin infections and anemia...
  19. Di T, Ruan Z, Zhao J, Wang Y, Liu X, Wang Y, et al. Astilbin inhibits Th17 cell differentiation and ameliorates imiquimod-induced psoriasis-like skin lesions in BALB/c mice via Jak3/Stat3 signaling pathway. Int Immunopharmacol. 2016;32:32-38 pubmed publisher
    The flavonoid astilbin is the major active component extracted from the rhizome of Smilax glabra, which has been widely used in China to treat inflammatory and autoimmune diseases, Psoriasis is a common chronic inflammatory disease in ..
  20. Lu Y, Chen D, Deng J, Tian L. [Effect of Smilax china on adjunctive arthritis mouse]. Zhong Yao Cai. 2003;26:344-6 pubmed
    To study the therapeutic action of decoction of Smilax china L. on adjunctive arthritis(AA) mouse and its mechanism. To observe the change of secondary inflammation, thymus and spleen weights, T cell subgroup, B cell, NK cell...
  21. Ruan J, Zou J, Cai Y. [Studies on chemical constituents of Smilax china]. Zhong Yao Cai. 2005;28:24-6 pubmed
    To study the chemical constituents of the 95% ethanol extract from the rhizome of Smilax china...
  22. Silva J, Andreata R, Appezzato da Glória B. Aerial organ anatomy of Smilax syphilitica (Smilacaceae). Rev Biol Trop. 2012;60:1137-48 pubmed
    b>Smilax L. in Brazil is represented by 32 taxa and it is a taxonomically difficult genus because the plants are dioecious and show wide phenotypic variation...
  23. Amado P, Ferraz V, da Silva D, Carollo C, Castro A, Alves Rodrigues Dos Santos Lima L. Chemical composition, antioxidant and cytotoxic activities of extracts from the leaves of Smilax brasiliensis Sprengel (Smilacaceae). Nat Prod Res. 2018;32:610-615 pubmed publisher
    ..and cytotoxic activities of petroleum ether and methanol extracts, fatty acids and methyl esters from leaves of Smilax brasiliensis were evaluated, and the composition of the extracts was determined...
  24. Zhang C, Xu Q, Tan X, Meng L, Wei G, Liu Y, et al. Astilbin decreases proliferation and improves differentiation in HaCaT keratinocytes. Biomed Pharmacother. 2017;93:713-720 pubmed publisher
    ..The flavonoid astilbin is the major active component extracted from the rhizome of Smilax glabra, which has been widely used in China to treat inflammatory and autoimmune diseases...
  25. Zhou M, Huang L, Li L, Wei Y, Shu J, Liu X, et al. New furostanol saponins with anti-inflammatory and cytotoxic activities from the rhizomes of Smilax davidiana. Steroids. 2017;127:62-68 pubmed publisher
    Seven new furostanol saponins have been isolated from the rhizomes of Smilax davidiana...
  26. Guo W, Dong H, Wang D, Yang B, Wang X, Huang L. Separation of Seven Polyphenols from the Rhizome of Smilax glabra by Offline Two Dimension Recycling HSCCC with Extrusion Mode. Molecules. 2018;23: pubmed publisher
    ..2D R-HSCCC) strategy with extrusion mode was developed for isolating polyphenols from the rhizome of Smilax glabra. Firstly, the ethyl acetate extract was divided into two fractions, Fr.1 and Fr...
  27. Kim J, Kim J. Comparative genome analysis and phylogenetic relationship of order Liliales insight from the complete plastid genome sequences of two Lilies (Lilium longiflorum and Alstroemeria aurea). PLoS ONE. 2013;8:e68180 pubmed publisher
    ..longflorum and L. superbum. Gene content and order were conserved in the order Liliales except infA loss in Smilax and Alstroemeria...
  28. Shou Q, Pan S, Tu J, Jiang J, Ling Y, Cai Y, et al. Modulation effect of Smilax glabra flavonoids on ryanodine receptor mediated intracellular Ca2+ release in cardiomyoblast cells. J Ethnopharmacol. 2013;150:389-92 pubmed publisher
    b>Smilax glabra rhizome, a plant material from Liliaceae family, is a widely used traditional Chinese medicine for anti-cardiac hypertrophy treatment...
  29. Duong N, Vinh P, Thuong P, Hoai N, Thanh L, Bach T, et al. Xanthine oxidase inhibitors from Archidendron clypearia (Jack.) I.C. Nielsen: Results from systematic screening of Vietnamese medicinal plants. Asian Pac J Trop Med. 2017;10:549-556 pubmed publisher
    ..The extracts of Archidendron clypearia (A. clypearia), Smilax poilanei, Linociera ramiflora and Passiflora foetida exhibited the greatest potency with IC50 values ..
  30. Shu J, Li L, Zhou M, Yu J, Peng C, Shao F, et al. Three new flavonoid glycosides from Smilax glabra and their anti-inflammatory activity. Nat Prod Res. 2017;:1-9 pubmed publisher
    ..3), together with five known flavonoids (4-8) were isolated from the roots of Smilax glabra Roxb...
  31. Huang H, Zhang J, Chen G, Lu Z, Wang X, Sha N, et al. High performance liquid chromatographic method for the determination and pharmacokinetic studies of oxyresveratrol and resveratrol in rat plasma after oral administration of Smilax china extract. Biomed Chromatogr. 2008;22:421-7 pubmed
    ..The validated method was used to study the pharmacokinetic profiles of OXY and RES in rat plasma after oral administration of Smilax china root extract.
  32. Huang H, Liu R, Shao F. Structural determination of two new steroidal saponins from Smilax china. Magn Reson Chem. 2009;47:741-5 pubmed publisher
    Two new steroidal saponins (1 and 2) were isolated from the BuOH fraction of the 70% EtOH extract of the tubes of Smilax china, together with four known analogues, 3-6...
  33. Chatzimanolis S. A revision of the myrmecophilous genus Smilax Laporte (Coleoptera: Staphylinidae: Staphylininae). Zootaxa. 2016;4162:283-303 pubmed publisher
    The neotropical myrmecophilous genus Smilax is revised and a new species, Smilax deneinephyto Chatzimanolis is described from southern Brazil. Lectotypes are designated for Smilax cyanea Wasmann and Staphylinus pilosus Fabricius...
  34. Ivanova A, Mikhova B, Batsalova T, Dzhambazov B, Kostova I. New furostanol saponins from Smilax aspera L. and their in vitro cytotoxicity. Fitoterapia. 2011;82:282-7 pubmed publisher
    ..2)-O-?-D-glucopyranoside, trans-resveratrol, (+) catechin and (-) epicatechin in the rhizomes of Smilax aspera is reported...
  35. Chen L, Yin H, Lan Z, Ma S, Zhang C, Yang Z, et al. Anti-hyperuricemic and nephroprotective effects of Smilax china L. J Ethnopharmacol. 2011;135:399-405 pubmed publisher
    b>Smilax china L., popularly known as "Jin Gang Ten", has been widely used as a traditional herbal medicine for the treatment of gout, rheumatoid arthritis and other diseases for a long time in China...
  36. Samarakoon S, Thabrew I, Galhena P, Tennekoon K. Modulation of apoptosis in human hepatocellular carcinoma (HepG2 cells) by a standardized herbal decoction of Nigella sativa seeds, Hemidesmus indicus roots and Smilax glabra rhizomes with anti- hepatocarcinogenic effects. BMC Complement Altern Med. 2012;12:25 pubmed publisher
    A standardized poly-herbal decoction of Nigella sativa seeds, Hemidesmus indicus roots and Smilax glabra rhizomes used traditionally in Sri Lanka for cancer therapy has been demonstrated previously, to have anti-hepatocarcinogenic ..
  37. Zhang C, Feng S, Zhang L, Ren Z. A new cytotoxic steroidal saponin from the rhizomes and roots of Smilax scobinicaulis. Nat Prod Res. 2013;27:1255-60 pubmed publisher
    A phytochemical investigation of the EtOH extract from the rhizomes and roots of Smilax scobinicaulis resulted in the isolation of a new isospirostanol-type steroidal saponin, namely (25 R)-5?-spirostan-3?,6?-diol 3-O-?-D-glucopyranosyl-(..
  38. Lincha V, Zhao B, Woo M, Yang I, Shin H. Effects of Constituent Compounds of Smilax china on Nicotine-Induced Endothelial Dysfunction in Human Umbilical Vein Endothelial Cells. Biol Pharm Bull. 2016;39:984-92 pubmed publisher
    This study investigated the effects of compounds isolated from 70% ethanol (EtOH) extraction of Smilax china L...
  39. Wang A, Chen Y, Chen G, Lee J, Fu C. Relationships and hybridization among Smilax china and its affinities: evidence from allozyme data. Biochem Genet. 2008;46:281-92 pubmed publisher
    b>Smilax china L. is a widespread species in China with different ploidy levels. It is morphologically similar to S. davidiana, S. trinervula, and S. glauco-china...
  40. Huang H, Chen G, Lu Z, Zhang J, Guo D. [Distribution study of two constituents in rat after oral administration of Smilax china extract]. Zhongguo Zhong Yao Za Zhi. 2009;34:2512-5 pubmed
    To investigate the distribution in rat after oral administration of Smilax china extract...
  41. Li X, Xu J, Zhang P, Li N, Meng D. A new naphthalene glycoside from the roots of Smilax bockii. Fitoterapia. 2008;79:479-80 pubmed publisher
    From the roots of Smilax bockii a new compound, 7-hydroxymethyl-1, 4, 5-trihydroxynaphthalene-4-O-beta-D-xylopyranosyl(1-->6)-beta-D-glucopyranoside, was isolated...
  42. Zhan X, Shi X, Duan T, Li L, Qiao Y. [Combination similarity algorithm on chromatographic fingerprints]. Se Pu. 2010;28:1071-6 pubmed
    ..their own appropriate weigh targeting for the maximal homostasis value of proportion among the peaks of all of Smilax glabra Roxb. samples...
  43. Ruangnoo S, Jaiaree N, Makchuchit S, Panthong S, Thongdeeying P, Itharat A. An in vitro inhibitory effect on RAW 264.7 cells by anti-inflammatory compounds from Smilax corbularia Kunth. Asian Pac J Allergy Immunol. 2012;30:268-74 pubmed
    b>Smilax corbularia is a Thai medicinal plant locally known as 'Hua-Khao-Yen Neua', which is used for treating inflammatory conditions. To evaluate the anti-inflammatory effect of S...
  44. Xu W, Yin L, Pan H, Shi L, Xu L, Zhang X, et al. Study on the correlation between constituents detected in serum from Rhizoma Smilacis Glabrae and the reduction of uric acid levels in hyperuricemia. J Ethnopharmacol. 2013;150:747-54 pubmed publisher
    ..These findings provide potent evidence for the study on RSG as a pharmacodynamic material basis and for developing RSG as a safe and promising natural drug to prevent hyperuricemia and gout instead of allopurinol. ..
  45. Wang M, Yang X, Zhao J, Lu C, Zhu W. Structural characterization and macrophage immunomodulatory activity of a novel polysaccharide from Smilax glabra Roxb. Carbohydr Polym. 2017;156:390-402 pubmed publisher
    A novel heteropolysaccharide (SGRP1) with great immunomodulatory activity was isolated from the root of Smilax glabra Roxb. by hot water extraction. Physical and chemical analyses showed that SGRP1 had an average molecular weight of 1...
  46. Guo H, Koike K, Li W, Guo D, Nikaido T. Maltol glucosides from the tuber of Smilax bockii. Phytochemistry. 2004;65:481-4 pubmed
    Two maltol glucosides, bockiosides A and B, along with 10 known compounds, were isolated from the tuber of Smilax bockii (Liliaceae), and their structures were elucidated by spectral experiments, chemical analysis and comparison with ..
  47. Ban J, Jeon S, Bae K, Song K, Seong Y. Catechin and epicatechin from Smilacis chinae rhizome protect cultured rat cortical neurons against amyloid beta protein (25-35)-induced neurotoxicity through inhibition of cytosolic calcium elevation. Life Sci. 2006;79:2251-9 pubmed
    ..Furthermore, these effects of catechin and epicatechin may be associated with the neuroprotective effect of the S. chinae rhizome. ..
  48. Wang G, Xu S, Gan G, Liu Y. [Comparison of resveratrol content of Smilax china from different habitats]. Zhongguo Zhong Yao Za Zhi. 2006;31:1054-5 pubmed
    To compare the content of the active ingredient resveratrol in Smilax china from different habitats. The ingredients of samples from different habitats in China were analyzed for resveratrol in S. china by HPLC...
  49. Ban J, Cho S, Choi S, Ju H, Kim J, Bae K, et al. Neuroprotective effect of Smilacis chinae rhizome on NMDA-induced neurotoxicity in vitro and focal cerebral ischemia in vivo. J Pharmacol Sci. 2008;106:68-77 pubmed
  50. Huang A, Wilde A, Ebmeyer J, Skouroumounis G, Taylor D. Examination of the phenolic profile and antioxidant activity of the leaves of the Australian native plant Smilax glyciphylla. J Nat Prod. 2013;76:1930-6 pubmed publisher
    ..8), have been isolated from the ethanolic extract of the leaves of Smilax glyciphylla for the first time...
  51. Deshpande S, Deshpande V, Potdar S. Effect of panchakarma and Ayurvedic treatment in postpartum rheumatoid arthritis (amavata): A case study. J Ayurveda Integr Med. 2017;8:42-44 pubmed publisher
    ..Dashamoola katutraya kashaya and combination of Swarnabhupati rasa, Tapyadi loha, Mahavatavidhvansa, Chopachini (Smilax china), Shunthi (Zinziber officinale) and Guduchi (Tinospora cordifolia) for four months and course of kala basti (..
  52. Zhang L, Zhu J, Sun M, Song Y, Rahman K, Peng C, et al. Anti-inflammatory effect of Man-Pen-Fang, a Chinese herbal compound, on chronic pelvic inflammation in rats. J Ethnopharmacol. 2017;208:57-65 pubmed publisher
    ..Cruciferae), Gleditsia sinensis Lam. (Leguminosae), Smilax china L. (Liliaceae), Euonymus alatus (Thunb.) Sieb. (Celastraceae) and Vaccaria segetalis (Neck...
  53. Xu S, Wang G, Gan G, Li Q, Liu Y. [Research on correlations of quality and growing environment of Smilax China]. Zhong Yao Cai. 2005;28:1055-6 pubmed
    To establish a method to examine the contents of diosgenin of Smilax china L. in different fields ,and to evaluate the influence of the growing environment on its quality. Kromasie C18 column was used...
  54. Abdala S, Martin Herrera D, Benjumea D, Gutiérrez S. Diuretic activity of some Smilax canariensis fractions. J Ethnopharmacol. 2012;140:277-81 pubmed publisher
    b>Smilax canariensis is an endemic species of the Canary Islands, popularly known as "Zarzaparrilla sin espinas"...
  55. Liu L, Huang H, Liu R, Ren G, Shao F, Ye Y, et al. A new lyoniresinol derivative from Smilax microphylla. Nat Prod Commun. 2013;8:113-4 pubmed
    ..3), oxyresveratrol (4), quercetin-3'-glucoside (5) and diosgenin (6) were isolated from the rhizomes of Smilax microphylla...
  56. Zhou X, Xu Q, Li J, Chen T. Structural revision of two flavanonol glycosides from Smilax glabra. Planta Med. 2009;75:654-5 pubmed publisher
    The structures of two flavanonol glycosides isolated from Smilax glabra, named smitilbin and neosmitilbin, have been revised to isoastilbin and neoastilbin, respectively...
  57. Wu X, Liu Z, Yan R, Sun W. [Separation and purification of total flavonoids in Smilax glabra by polyamide resins]. Zhong Yao Cai. 2009;32:1606-9 pubmed
    To investigate the process of separating and purifying total flavonoids from Smilax glabra...
  58. Chatterjee I, Chakravarty A, Gomes A. Daboia russellii and Naja kaouthia venom neutralization by lupeol acetate isolated from the root extract of Indian sarsaparilla Hemidesmus indicus R.Br. J Ethnopharmacol. 2006;106:38-43 pubmed
    ..Venom induced changes in lipid peroxidation and super oxide dismutase activity was antagonized by lupeol acetate. Snake venom neutralization by lupeol acetate and its possible mechanism of action has been discussed...
  59. Li G, Jiang W, Yue X, Qu G, Tian J, Wu J, et al. Effect of astilbin on experimental diabetic nephropathy in vivo and in vitro. Planta Med. 2009;75:1470-5 pubmed publisher
    Astilbin, a flavonoid compound, was isolated from the rhizome of Smilax glabra Roxb...
  60. Huang H, Chen G, Lu Z, Zhang J, Guo D. Identification of seven metabolites of oxyresveratrol in rat urine and bile using liquid chromatography/tandem mass spectrometry. Biomed Chromatogr. 2010;24:426-32 pubmed publisher
    Oxyresveratrol (trans-2,4,3',5'-tetrahydroxystilbene) is a major compound isolated from Smilax china, a Chinese herbal medicine...
  61. Martins A, Soares A, Bombo A, Fidelis A, Novembre A, da Glória B. Germination and seedling morphology of four South American Smilax (Smilacaceae). Rev Biol Trop. 2012;60:495-504 pubmed
    Species of Smilax, also known as greenbrier, are widely distributed in Brazil and their commercial trades are carried out by the extractivism of native species...
  62. Chen J, Xiong C, Song S, Han P, Ruan J. Fraction of macroporous resin from Smilax china L. inhibits testosterone propionate-induced prostatic hyperplasia in castrated rats. J Med Food. 2012;15:646-50 pubmed publisher
    ..study was conducted to evaluate the effect of a fraction of macroporous resin (FMR), a bioactive component of Smilax china L., on benign prostatic hyperplasia (BPH) in castrated rats induced by testosterone propionate...
  63. Ki N, Park E, Sung I, Ju S, Kim K, Kim M, et al. The Hot-Water Extract of Smilacis Chinae Rhizome Suppresses 2,4-Dinitrochlorobenzene and House Dust Mite-Induced Atopic Dermatitis-Like Skin Lesions in Mice. Phytother Res. 2016;30:636-45 pubmed publisher
  64. Chen D, Hua X, Yu L. [Research on the application of supercritical fluid extraction of diosgenin of Smilax china]. Zhong Yao Cai. 2008;31:120-2 pubmed
    ..To Study the optimum extraction conditions of diosgenin by CO2 Supercritical Fluid Extraction ( SFE)...
  65. Yang A, Guo X. [Chemical constituents of rhizomes of Smilax ferox]. Zhongguo Zhong Yao Za Zhi. 2010;35:2293-5 pubmed
    To study the chemical constituents of the rhizomes of Smilax ferox which was widely used in the folk.
  66. Chen L, Lan Z, Zhou Y, Li F, Zhang X, Zhang C, et al. Astilbin attenuates hyperuricemia and ameliorates nephropathy in fructose-induced hyperuricemic rats. Planta Med. 2011;77:1769-73 pubmed publisher
    Astilbin is a flavonoid compound isolated from the rhizome of Smilax china L. The effects and possible mechanisms of astilbin on hyperuricemia and nephropathy rats were elucidated in this study. Different dosages of astilbin (1.25, 2...
  67. Amira S, Dade M, Schinella G, Rios J. Anti-inflammatory, anti-oxidant, and apoptotic activities of four plant species used in folk medicine in the Mediterranean basin. Pak J Pharm Sci. 2012;25:65-72 pubmed
    ..of this research was to study the potential anti-inflammatory activity of myrtle (Myrtus communis), sarsaparilla (Smilax aspera), Arabian or French lavender (Lavandula stoechas), and calamint (Calamintha nepeta) along with their ..
  68. Challinor V, Parsons P, Chap S, White E, Blanchfield J, Lehmann R, et al. Steroidal saponins from the roots of Smilax sp.: structure and bioactivity. Steroids. 2012;77:504-11 pubmed publisher
    Phytochemical characterization of a commercial herb sample supplied as Smilax ornata Lem...
  69. Delgado Pelayo R, Hornero Méndez D. Identification and quantitative analysis of carotenoids and their esters from sarsaparilla (Smilax aspera L.) berries. J Agric Food Chem. 2012;60:8225-32 pubmed publisher
    The carotenoid composition of sarsaparilla ( Smilax aspera L.) berries has been analyzed for the first time. Lycopene was found to be the main carotenoid (242.44 ?g/g fresh wt) in the pulp, followed by ?-carotene (65...
  70. Zheng Z, Duan T, He B, Tang D, Jia X, Wang R, et al. Macrophage biospecific extraction and HPLC-ESI-MSn analysis for screening immunological active components in Smilacis Glabrae Rhizoma. J Pharm Biomed Anal. 2013;77:44-8 pubmed publisher
    ..In conclusion, the application of macrophage biospecific extraction coupled with HPLC-ESI-MS(n) analysis is a rapid, simple and reliable method for screening immunological active components from Traditional Chinese Medicine...
  71. Wang P, Xu J, Wang Q, Feng S, Chen T, Zhang C. [Phenylpropanoids and diphenylethene compounds from roots and rhizomes of Smilax scobinicaulis]. Zhongguo Zhong Yao Za Zhi. 2013;38:1531-5 pubmed
    The chemical constituents were separated and purified from the roots and rhizomes of Smilax scobinicaulis by various chromatographic methods including silica gel, Sephadex LH-20...
  72. Alessio G, De Lillis M, Brugnoli E, Lauteri M. Water sources and water-use efficiency in mediterranean coastal dune vegetation. Plant Biol (Stuttg). 2004;6:350-7 pubmed
    ..shrubs and climbers (Arbutus unedo, Pistacia lentiscus, Phillyrea angustifolia, Qercus ilex, Juniperus oxycedrus, Smilax aspera) of consolidated dunes...
  73. Yip E, Liu A, Wong J, Wong Y. An aqueous extract of the popular Chinese nutraceutical Kwei Ling Ko (Tortoise shell-Rhizome jelly) activates the PPARgamma pathway and down-regulates the NFkappaB activity. Phytomedicine. 2005;12:748-59 pubmed
    ..As activation of PPAR pathway has a dual role in adipogenesis and anti-inflammation, our observations are consistent with the notion that KLK possesses antiinflammatory properties...
  74. Li W, Yan Y, Ye X, Yang X. [Study on separation and purification of total flavones from Smilax china by macroporous absorption resin]. Zhongguo Zhong Yao Za Zhi. 2007;32:1292-5 pubmed
    To investigate the technological parameters of the purification process of total flavones from Smilax china with macroporous absorption resin.
  75. Ooi L, Wong E, Chiu L, Sun S, Ooi V. Antiviral and anti-proliferative glycoproteins from the rhizome of Smilax glabra Roxb (Liliaceae). Am J Chin Med. 2008;36:185-95 pubmed
    ..glycoproteins possessing antiviral and anti-proliferative activities were isolated from the Chinese medicinal herb Smilax glabra (known as tufuling), by extraction with 0...
  76. Belhouchet Z, Sautour M, Miyamoto T, Lacaille Dubois M. Steroidal saponins from the roots of Smilax aspera subsp. mauritanica. Chem Pharm Bull (Tokyo). 2008;56:1324-7 pubmed
    Two new steroidal saponins (1, 2) were isolated from the roots of Smilax aspera subsp. mauritanica (POIR.) ARCANG...
  77. Xu Y, Liang J, Zou Z. [Studies on chemical constituents of rhizomes of Smilax china]. Zhongguo Zhong Yao Za Zhi. 2008;33:2497-9 pubmed
    To study the chemical constituents of the rhizomes of Smilax china.
  78. Xia D, Wang H, Yang Q, Jiang L, Xia M. [Therapeutic effects of traditional Chinese herbal formula with Smilax glabra on mice's lead poisoning]. Zhong Yao Cai. 2009;32:404-6 pubmed
    To investigate the influence of traditional Chinese herbal formula with Smilax glabra on lead expelling and oxidative damage in lead-poisoned mice.
  79. Laitonjam W, Kongbrailatpam B. Studies on the chemical constituents and antioxidant activities of extracts from the roots of Smilax lanceaefolia Roxb. Nat Prod Res. 2010;24:1168-76 pubmed publisher
    ..steroidal saponin (2), along with beta-sitosterol and beta-sitosterol-D-glucoside, were isolated from the roots of Smilax lanceaefolia Roxb...
  80. Pizzaia D, Oliveira V, Martins A, Appezzato da Glória B, Forni Martins E, Aguiar Perecin M. Karyotype characterization reveals active 45S rDNA sites located on chromosome termini in Smilax rufescens (Smilacaceae). Genet Mol Res. 2013;12:1303-10 pubmed publisher
    The genus Smilax (Smilacaceae) includes species of medicinal interest; consequently, their identification is important for the control of raw material used in the manufacture of phytotherapeutic products...
  81. Arora S, Aggarwal A, Singla P, Jyoti S, Tandon S. Anti-proliferative effects of homeopathic medicines on human kidney, colon and breast cancer cells. Homeopathy. 2013;102:274-82 pubmed publisher
    ..This study provides preliminary laboratory evidence indicating the ability of homeopathic medicines as anticancer agents. Further studies of the action of these homeopathic remedies are warranted. ..
  82. Cheng Y, Zhang D, Yu S, Ding Y. [Study on chemical constituents in rhizome of Smilax perfoliate]. Zhongguo Zhong Yao Za Zhi. 2003;28:233-5 pubmed
    To investigate the components of Smilax perfoliate.
  83. Ang H, Lee K, Kiyoshi M. Determination of lead in Smilax myosotiflora herbal preparations obtained in Malaysia. Int J Environ Health Res. 2004;14:261-72 pubmed
    ..As such, a total of 100 traditional medicinal preparations, containing Smilax myosotiflora, in various pharmaceutical dosage forms, which were bought in the Malaysian market, were analysed for ..
  84. Yuan J, Dou D, Chen Y, Li W, Kazuo K, Tamotsu N, et al. [Studies on dihydroflavonol glycosides from rhizome of Smilax glabra]. Zhongguo Zhong Yao Za Zhi. 2004;29:867-70 pubmed
    To investigate the chemical constituents from the rhizomes of Smilax glabra.
  85. Olano J, Menges E, Martinez E. Carbohydrate storage in five resprouting Florida scrub plants across a fire chronosequence. New Phytol. 2006;170:99-105 pubmed
    ..In areas with long intervals between fires, this carbohydrate reduction could affect subsequent postfire resprouting vigour, although this remains to be confirmed...
  86. Shu X, Gao Z, Yang X. [The anti-inflammation effects of Smilax china ethylacetate extract in rats and mice]. Zhongguo Zhong Yao Za Zhi. 2006;31:239-43 pubmed
    ..To study the anti-inflammations of the ethyl acetate extract of S. china on acute and chronic inflammations...
  87. Sautour M, Miyamoto T, Lacaille Dubois M. Bioactive steroidal saponins from Smilax medica. Planta Med. 2006;72:667-70 pubmed
    Two new spirostanol saponins ( 1 and 2) were isolated from the roots of Smilax medica, together with the known smilagenin 3-O-beta-D-glucopyranoside (3)...
  88. Wang Y, Li L, Zhang H, Qiao Y. [Identification of dihydroflavonol glycoside isomers in Smilax glabra by HPLC-MS and HPLC-1H NMR]. Zhongguo Zhong Yao Za Zhi. 2008;33:1281-4 pubmed
    To identify dihydroflavonol glycoside isomers in Smilax glabra.
  89. Vega Villa K, Remsberg C, Ohgami Y, Yáñez J, Takemoto J, Andrews P, et al. Stereospecific high-performance liquid chromatography of taxifolin, applications in pharmacokinetics, and determination in tu fu ling (Rhizoma smilacis glabrae) and apple (Malus x domestica). Biomed Chromatogr. 2009;23:638-46 pubmed publisher
    ..The assay was successfully applied to stereospecific disposition of taxifolin enantiomers in rats and to the quantification of taxifolin enantiomers in tu fu ling (Rhizoma smilacis glabrae) and apple (Malus x domestica)...
  90. Ivanova A, Mikhova B, Klaiber I, Dinchev D, Kostova I. Steroidal saponins from Smilax excelsa rhizomes. Nat Prod Res. 2009;23:916-24 pubmed publisher
    From the n-butanol soluble fraction of the methanol extract of the rhizomes of Smilax excelsa, three new furostanol saponins 3-O-[4-O-acetyl-alpha-L-rhamnopyranosyl-(1 --> 2)-{alpha-L-rhamnopyranosyl-(1 --> 4)}-beta-D-glucopyranosyl]..
  91. Wang W, Qian J, Wang X, Jiang A, Jia A. Anti-HIV-1 activities of extracts and phenolics from Smilax china L. Pak J Pharm Sci. 2014;27:147-51 pubmed
    ..2), kaempferol-7-O-?-D-glucoside (3), dihydrokaempferol-3-O-?-L-rhamnoside (4), oxyresveratrol (5)) from Smilax china L. was evaluated for anti-HIV-1 activities and cytotoxicity activities in vitro...
  92. Cox S, Jayasinghe K, Markham J. Antioxidant activity in Australian native sarsaparilla (Smilax glyciphylla). J Ethnopharmacol. 2005;101:162-8 pubmed
    A hot water extract of the Australian native sarsaparilla Smilax glyciphylla Sm. (Smilaceae) inhibited peroxidation of phosphatidylcholine liposomes initiated by Fe(2+)/ascorbate (IC50, 10 microg/mL) and AAPH (IC50, 33 microg/mL) in vitro...