ornithogalum

Summary

Summary: A plant genus of the family LILIACEAE that contains cholestane glycosides (CHOLESTANES).

Top Publications

  1. Fuji S, Inoue M, Yamamoto H, Furuya H, Naito H, Matsumoto T. Nucleotide sequences of the coat protein gene of potyviruses infecting Ornithogalum thyrsoides. Arch Virol. 2003;148:613-21 pubmed
    Species of three viral genera infecting Ornithogalum thyrsoides plants showing mosaic symptoms were identified using RT-PCR and degenerate universal primers for each viral genus...
  2. Kwiatkowska M, Popłońska K, Wojtczak A, Stepinski D, Polit J. Lipid body biogenesis and the role of microtubules in lipid synthesis in Ornithogalum umbellatum lipotubuloids. Cell Biol Int. 2012;36:455-62 pubmed publisher
    Lipid bodies present in lipotubuloids of Ornithogalum umbellatum ovary epidermis take the form of a lens between leaflets of ER (endoplasmic reticulum) membrane filled with a highly osmiophilic substance...
  3. Kwiatkowska M, Stepinski D, Popłońska K. Diameters of microtubules change during rotation of the lipotubuloids of Ornithogalum umbellatum stipule epidermis as a result of varying protofilament monomers sizes and distance between them. Cell Biol Int. 2009;33:1245-52 pubmed publisher
    Microtubules in lipotubuloids of the Ornithogalum umbellatum stipule epidermis cells change their diameters depending on the motion of the cytoplasmic domains rich in microtubules and lipid bodies...
  4. Schliemann W, Schmidt J, Nimtz M, Wray V, Fester T, Strack D. Accumulation of apocarotenoids in mycorrhizal roots of Ornithogalum umbellatum. Phytochemistry. 2006;67:1196-205 pubmed
    Colonization of roots of Ornithogalum umbellatum by the arbuscular mycorrhizal fungus Glomus intraradices induced the accumulation of different types of apocarotenoids...
  5. Golan A, Kerem Z, Tun O, Luzzatto T, Lipsky A, Yedidia I. Combining flow cytometry and gfp reporter gene for quantitative evaluation of Pectpbacterium carotovorum ssp. carotovorum in Ornithogalum dubium plantlets. J Appl Microbiol. 2010;108:1136-44 pubmed publisher
    b>Ornithogalum dubium is a natural host of the soft rot pathogen Pectobacterium carotovorum ssp. carotovorum (Pcc)...
  6. Kwiatkowska M, Poplonska K, Kazmierczak A, Stepinski D, Rogala K, Polewczyk K. Role of DNA endoreduplication, lipotubuloids, and gibberellic acid in epidermal cell growth during fruit development of Ornithogalum umbellatum. J Exp Bot. 2007;58:2023-31 pubmed
    ..to examine the level of endoreduplication in epidermal cells from the upper and lower parts of the ovary during Ornithogalum umbellatum flower and fruit development...
  7. Guo L, Chen X, Li L, Tang W, Pan Y, Kong J. Transcriptome-enabled discovery and functional characterization of enzymes related to (2S)-pinocembrin biosynthesis from Ornithogalum caudatum and their application for metabolic engineering. Microb Cell Fact. 2016;15:27 pubmed publisher
    ..Specifically, a transcriptome-wide search for genes related to (2S)-pinocembrin biosynthesis from Ornithogalum caudatum, a plant rich in flavonoids, was first performed in the present study...
  8. Lipsky A, Joshi J, Carmi N, Yedidia I. Expression levels of antimicrobial peptide tachyplesin I in transgenic Ornithogalum lines affect the resistance to Pectobacterium infection. J Biotechnol. 2016;238:22-29 pubmed publisher
    The genus Ornithogalum includes several ornamental species that suffer substantial losses from bacterial soft rot caused by Pectobacteria...
  9. Yin S, Kong J. Transcriptome-guided gene isolation and functional characterization of UDP-xylose synthase and UDP-D-apiose/UDP-D-xylose synthase families from Ornithogalum caudatum Ait. Plant Cell Rep. 2016;35:2403-2421 pubmed
    ..acid to UDP-D-xylose, are believed to transfer xylosyl residue to anticancer polysaccharides biosynthesis in Ornithogalum caudatum Ait...

More Information

Publications38

  1. Cho S, Lim S, Kim H, Yi S, Moon J. Complete Genome Sequence of Ornithogalum Mosaic Virus Infecting Gladiolus spp. in South Korea. Genome Announc. 2016;4: pubmed publisher
    We report here the first complete genome sequence of Ornithogalum mosaic virus (OrMV) isolated from Taean, South Korea, in 2011, which was obtained by next-generation sequencing and Sanger sequencing...
  2. Hesami R, Salimi A, Ghaderian S. Lead, zinc, and cadmium uptake, accumulation, and phytoremediation by plants growing around Tang-e Douzan lead-zinc mine, Iran. Environ Sci Pollut Res Int. 2018;25:8701-8714 pubmed publisher
    ..neglectum, Ornithogalum orthophyllum, and Ranunculus arvensis for Zn and C. falcata, M. neglectum, O. orthophyllum, and R...
  3. Yin S, Liu M, Kong J. Functional analyses of OcRhS1 and OcUER1 involved in UDP-L-rhamnose biosynthesis in Ornithogalum caudatum. Plant Physiol Biochem. 2016;109:536-548 pubmed publisher
    ..UDP-4K6DG) 3, 5-epimerase/UDP-4-keto-L-rhamnose (UDP-4KR) 4-keto-reductase (UER) were isolated from Ornithogalum caudatum based on the RNA-Seq data...
  4. Yin S, Sun Y, Liu M, Li L, Kong J. cDNA Isolation and Functional Characterization of UDP-d-glucuronic Acid 4-Epimerase Family from Ornithogalum caudatum. Molecules. 2016;21: pubmed
    d-Galacturonic acid (GalA) is an important component of GalA-containing polysaccharides in Ornithogalum caudatum. The incorporation of GalA into these polysaccharides from UDP-d-galacturonic acid (UDP-GalA) was reasonably known...
  5. Liu M, Li L, Pan Y, Kong J. cDNA isolation and functional characterization of squalene synthase gene from Ornithogalum caudatum. Protein Expr Purif. 2017;130:63-72 pubmed publisher
    ..efforts to investigate the genes responsible for the biosynthesis of steroidal saponins in the medicinal plant Ornithogalum caudatum, this investigation reported the cDNA isolation, prokaryotic expression and functional ..
  6. Rat M, Gavaric N, Kladar N, Andric A, Anackov G, Božin B. The Phenolics of the Ornithogalum umbellatum L. (Hyacinthaceae): Phytochemical and Ecological Characterization. Chem Biodivers. 2016;13:1551-1558 pubmed publisher
    b>Ornithogalum umbellatum L. is a widely distributed species in Europe, that exhibits considerable variability at ecological, morphological, anatomical, and karyological level...
  7. Malabed R, Hanashima S, Murata M, Sakurai K. Sterol-recognition ability and membrane-disrupting activity of Ornithogalum saponin OSW-1 and usual 3-O-glycosyl saponins. Biochim Biophys Acta Biomembr. 2017;1859:2516-2525 pubmed publisher
    OSW-1 is a structurally unique steroidal saponin isolated from the bulbs of Ornithogalum saundersiae, and has exhibited highly potent and selective cytotoxicity in tumor cell lines...
  8. Iguchi T, Kuroda M, Naito R, Watanabe T, Matsuo Y, Yokosuka A, et al. Structural Characterization of Cholestane Rhamnosides from Ornithogalum saundersiae Bulbs and Their Cytotoxic Activity against Cultured Tumor Cells. Molecules. 2017;22: pubmed publisher
    Previous phytochemical studies of the bulbs of Ornithogalum saundersiae, an ornamental perennial plant native to South Africa, resulted in the isolation of 29 new cholestane glycosides, some of which were structurally unique and ..
  9. Salachna P, Grzeszczuk M, Sobol M. Effects of Chitooligosaccharide Coating Combined with Selected Ionic Polymers on the Stimulation of Ornithogalum saundersiae Growth. Molecules. 2017;22: pubmed publisher
    ..Our three-year study investigated coating the bulbs of Ornithogalum saundersiae with chitooligosaccharide (COS), sodium alginate, carrageenan, gellan gum and xanthan gum...
  10. Ramesh V, Selvarasu K, Pandian J, Myilsamy S, Shanmugasundaram C, Ganesan K. NF?B activation demarcates a subset of hepatocellular carcinoma patients for targeted therapy. Cell Oncol (Dordr). 2016;39:523-536 pubmed
    ..Through NF?B inhibitor screening we observed a highly efficacious NF?B pathway inhibitory potential of ornithogalum in HCC-derived HEP3B cells...
  11. Iriel A, Lagorio M. Is the flower fluorescence relevant in biocommunication?. Naturwissenschaften. 2010;97:915-24 pubmed publisher
    ..the fluorescence quantum yield (?(f)) for flowers of Bellis perennis (white, yellow, pink, and purple), Ornithogalum thyrsoides (petals and ovaries), Limonium sinuatum (white and yellow), Lampranthus productus (yellow), Petunia ..
  12. Yishay M, Burdman S, Valverde A, Luzzatto T, Ophir R, Yedidia I. Differential pathogenicity and genetic diversity among Pectobacterium carotovorum ssp. carotovorum isolates from monocot and dicot hosts support early genomic divergence within this taxon. Environ Microbiol. 2008;10:2746-59 pubmed publisher
    ..plants, we used as model plants two susceptible monocot hosts, the ornamentals Zantedeschia aethiopica and Ornithogalum dubium, as well as two common dicot hosts, Solanum tuberosum and Brassica oleracea...
  13. Zheng D, Zhou L, Guan Y, Chen X, Zhou W, Chen X, et al. Synthesis of cholestane glycosides bearing OSW-1 disaccharide or its 1-->4-linked analogue and their antitumor activities. Bioorg Med Chem Lett. 2010;20:5439-42 pubmed publisher
    ..Their cytotoxic activities were evaluated by the standard MTT assay. Compound 1 showed potent cytotoxicity against five types of human tumor cells, with IC50 ranging between 1.3 and 73 nM...
  14. Tang P, Mamdani F, Hu X, Liu J, Yu B. Synthesis of OSW saponin analogs with modified sugar residues and their antiproliferative activities. Bioorg Med Chem Lett. 2007;17:1003-7 pubmed
    ..One analog, 2-O-acetyl-alpha-l-arabinopyranoside 3, showed antiproliferative activity against the Jurkat cells (IC(50)=0.078microM) comparable to that of the disaccharide derivative (1)...
  15. Shi B, Wu H, Yu B, Wu J. 23-oxa-analogues of OSW-1: efficient synthesis and extremely potent antitumor activity. Angew Chem Int Ed Engl. 2004;43:4324-7 pubmed
  16. Xue J, Liu P, Pan Y, Guo Z. A total synthesis of OSW-1. J Org Chem. 2008;73:157-61 pubmed
    ..The synthesis was achieved in 10 linear steps with an overall yield of 6.4% starting from (+)-dehydroisoandrosterone...
  17. Kuroda M, Mimaki Y, Ori K, Sakagami H, Sashida Y. Steroidal glycosides from the bulbs of Ornithogalum thyrsoides. J Nat Prod. 2004;67:1690-6 pubmed
    Phytochemical analyses have been carried out on the fresh bulbs of Ornithogalum thyrsoides with particular attention to the steroidal glycoside constituents, resulting in the isolation of four new spirostanol saponins and seven new ..
  18. Verschaeve L, Kestens V, Taylor J, Elgorashi E, Maes A, Van Puyvelde L, et al. Investigation of the antimutagenic effects of selected South African medicinal plant extracts. Toxicol In Vitro. 2004;18:29-35 pubmed
    Dichloromethane extracts from different parts of Rhamnus prinoides, Ornithogalum longibracteatum, Gardenia volkensii, Spirostachys africana, Diospyros whyteana, Syzigium cordatum and Prunus africana were investigated for mutagenic and ..
  19. Morzycki J, Wojtkielewicz A, Wołczyński S. Synthesis of analogues of a potent antitumor saponin OSW-1. Bioorg Med Chem Lett. 2004;14:3323-6 pubmed
    ..All analogues were found to be less cytotoxic against breast and endometrial cancer cell lines than the natural product...
  20. Kuroda M, Mimaki Y, Yokosuka A, Hasegawa F, Sashida Y. Cholestane glycosides from the bulbs of Ornithogalum thyrsoides and their cytotoxic activity against HL-60 leukemia cells. J Nat Prod. 2002;65:1417-23 pubmed
    ..Twelve bisdesmosidic cholestane glycosides (1-12), including nine new ones (1-9), were isolated from the bulbs of Ornithogalum thyrsoides by monitoring the cytotoxic activity on HL-60 leukemia cells...
  21. Dabrowska R, Kulikova N, Gagola M. Nonmuscle caldesmon: its distribution and involvement in various cellular processes. Review article. Protoplasma. 2004;224:1-13 pubmed
    ..Examples of nonmuscle caldesmon involvement in functions of higher and lower eukaryote, animal and plant cells are presented...
  22. Jin J, Jin X, Zhang X, Piao Y, Liu S. Effect of OSW-1 on microRNA expression profiles of hepatoma cells and functions of novel microRNAs. Mol Med Rep. 2013;7:1831-7 pubmed publisher
    ..OSW-1) is a member of the cholestane saponin family, which was first isolated from the bulbs of Ornithogalum saundersiae and previously reported to be cytotoxic against several types of malignant cells...
  23. Kuroda M, Ori K, Mimaki Y. Ornithosaponins A-D, four new polyoxygenated steroidal glycosides from the bulbs of Ornithogalumthyrsoides. Steroids. 2006;71:199-205 pubmed
    By analyzing the steroidal glycoside content of fresh bulbs of Ornithogalum thyrsoides (Liliaceae), we were able to isolate four new polyoxygenated steroidal glycosides, which we named ornithosaponins A-D (1-4)...
  24. van Huyssteen M, Milne P, Campbell E, van de Venter M. Antidiabetic and cytotoxicity screening of five medicinal plants used by traditional African health practitioners in the Nelson Mandela Metropole, South Africa. Afr J Tradit Complement Altern Med. 2011;8:150-8 pubmed
    ..A collaborative research project with these practitioners focused on the screening of Bulbine frutescens, Ornithogalum longibracteatum, Ruta graveolens, Tarchonanthus camphoratus and Tulbaghia violacea for antidiabetic and ..
  25. Kwiatkowska M, Stepinski D, Polit J, Popłońska K, Wojtczak A. Microtubule heterogeneity of Ornithogalum umbellatum ovary epidermal cells: non-stable cortical microtubules and stable lipotubuloid microtubules. Folia Histochem Cytobiol. 2011;49:285-90 pubmed
    Lipotubuloids, structures containing lipid bodies and microtubules, are described in ovary epidermal cells of Ornithogalum umbellatum...
  26. Kwiatkowska M, Popłońska K, Stepinski D, Hejnowicz Z. Microtubules with different diameter, protofilament number and protofilament spacing in Ornithogalum umbellatum ovary epidermis cells. Folia Histochem Cytobiol. 2006;44:133-8 pubmed
    Microtubules present in the epidermis of Ornithogalum umbellatum ovary in the area of lipotubuloids (i.e. aggregates of lipid bodies surrounded by microtubules) are 25-51 nm in diameter...
  27. Martínez Azorín M, Crespo M, Juan A, Fay M. Molecular phylogenetics of subfamily Ornithogaloideae (Hyacinthaceae) based on nuclear and plastid DNA regions, including a new taxonomic arrangement. Ann Bot. 2011;107:1-37 pubmed publisher
    ..Some authors have recognized only a single genus Ornithogalum for the whole subfamily, including 250-300 species of variable morphology, whereas others have recognized many ..
  28. Ying Wan -, Wu Y, Feng X, Lian L, Jiang Y, Nan J. The protective effects of total saponins from Ornithogalum saundersiae (Liliaceae) on acute hepatic failure induced by lipopolysaccharide and D-galactosamine in mice. J Ethnopharmacol. 2010;132:450-5 pubmed publisher
    This study examined the protective effects of total saponins from Ornithogalum saundersiae (Liliaceae) on D-galactosamine (D-GalN) and lipopolysaccharide (LPS)-induced fulminant hepatic failure.
  29. Kwiatkowska M, Popłońska K, Stepinski D. Actin filaments connected with the microtubules of lipotubuloids, cytoplasmic domains rich in lipid bodies and microtubules. Protoplasma. 2005;226:163-7 pubmed
    ..membrane, entwined and held together by a system of microtubules, have been found in the ovary epidermis of Ornithogalum umbellatum...