laurus

Summary

Summary: A plant genus in the LAURACEAE family. Laurus nobilis L. leaves are known for use in SPICES, having a similar flavor as UMBELLULARIA.

Top Publications

  1. Marzouki H, Piras A, Marongiu B, Rosa A, Dessi M. Extraction and separation of volatile and fixed oils from berries of Laurus nobilis L. by Supercritical CO2. Molecules. 2008;13:1702-11 pubmed
    Isolation of volatile and fixed oils from dried berries of Laurus nobilis L. from Tunisia have been obtained by supercritical fractioned extraction with carbon dioxide...
  2. Otsuka N, Liu M, Shiota S, Ogawa W, Kuroda T, Hatano T, et al. Anti-methicillin resistant Staphylococcus aureus (MRSA) compounds isolated from Laurus nobilis. Biol Pharm Bull. 2008;31:1794-7 pubmed
    We found that an extract from Laurus nobilis L. (Lauraceae) leaves showed antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA)...
  3. Ham A, Kim B, Koo U, Nam K, Lee S, Kim K, et al. Spirafolide from bay leaf (Laurus nobilis) prevents dopamine-induced apoptosis by decreasing reactive oxygen species production in human neuroblastoma SH-SY5Y cells. Arch Pharm Res. 2010;33:1953-8 pubmed publisher
    ..This study tested the neuroprotective effects of spirafolide, a compound purified from the leaves of Laurus nobilis L. (Lauraceae), against dopamine (DA)-induced apoptosis in human neuroblastoma SH-SY5Y cells...
  4. Julianti E, Jang K, Lee S, Lee D, Mar W, Oh K, et al. Sesquiterpenes from the leaves of Laurus nobilis L. Phytochemistry. 2012;80:70-6 pubmed publisher
    Ten sesquiterpenes, together with 12 known compounds were isolated from leaves of Laurus nobilis L. Based on spectroscopic analyses, the 10 compounds were determined to be eudesmane lactones and their corresponding methyl esters...
  5. Marzouki H, Piras A, Salah K, Medini H, Pivetta T, Bouzid S, et al. Essential oil composition and variability of Laurus nobilis L. growing in Tunisia, comparison and chemometric investigation of different plant organs. Nat Prod Res. 2009;23:343-54 pubmed publisher
    Stems, leaves, buds and flowers of Laurus nobilis L. growing wild in Tunisia were analysed for their essential oil composition. The essential oil of Laurus nobilis L...
  6. Nardini A, Grego F, Trifilò P, Salleo S. Changes of xylem sap ionic content and stem hydraulics in response to irradiance in Laurus nobilis. Tree Physiol. 2010;30:628-35 pubmed publisher
  7. Sayyah M, Valizadeh J, Kamalinejad M. Anticonvulsant activity of the leaf essential oil of Laurus nobilis against pentylenetetrazole- and maximal electroshock-induced seizures. Phytomedicine. 2002;9:212-6 pubmed
    The leaf essential oil of Laurus nobilis Linn., Lauraceae, which has been used as an antiepileptic remedy in Iranian traditional medicine, was evaluated for anticonvulsant activity against experimental seizures...
  8. Muñiz Márquez D, Martínez Ávila G, Wong Paz J, Belmares Cerda R, Rodríguez Herrera R, Aguilar C. Ultrasound-assisted extraction of phenolic compounds from Laurus nobilis L. and their antioxidant activity. Ultrason Sonochem. 2013;20:1149-54 pubmed publisher
    Bay leaves (BL) (Laurus nobilis L., Family: Laureceae) are traditionally used to treat some symptoms of gastrointestinal problems, such as epigastric bloating, impaired digestion, eructing and flatulence...
  9. Flamini G, Cioni P, Morelli I. Differences in the fragrances of pollen and different floral parts of male and female flowers of Laurus nobilis. J Agric Food Chem. 2002;50:4647-52 pubmed
    The headspace analyses of pollen, whole living female and male flowers, and staminoids have been performed on Laurus nobilis L...

More Information

Publications100

  1. Al Kalaldeh J, Abu Dahab R, Afifi F. Volatile oil composition and antiproliferative activity of Laurus nobilis, Origanum syriacum, Origanum vulgare, and Salvia triloba against human breast adenocarcinoma cells. Nutr Res. 2010;30:271-8 pubmed publisher
    ..The composition of the essential oils of Laurus nobilis L, Origanum syriacum L, Origanum vulgare L, and Salvia triloba L was analyzed by gas chromatography-mass ..
  2. Saab A, Tundis R, Loizzo M, Lampronti I, Borgatti M, Gambari R, et al. Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells. Nat Prod Res. 2012;26:1741-5 pubmed publisher
    The antioxidant and antiproliferative activities of the essential oils from Laurus nobilis leaves and seeds in relation to their composition were analysed...
  3. Simic M, Kundakovic T, Kovacevic N. Preliminary assay on the antioxidative activity of Laurus nobilis extracts. Fitoterapia. 2003;74:613-6 pubmed
    Antioxidative activity of Laurus nobilis leaves, bark and fruit methanolic extracts (crude and defatted) were studied on the level of lipid peroxidation in liposomes, induced by Fe(2+)/ascorbate system and measured spectrophotometrically ..
  4. Panza E, Tersigni M, Iorizzi M, Zollo F, De Marino S, Festa C, et al. Lauroside B, a megastigmane glycoside from Laurus nobilis (bay laurel) leaves, induces apoptosis in human melanoma cell lines by inhibiting NF-?B activation. J Nat Prod. 2011;74:228-33 pubmed publisher
    ..propensity against human melanoma cell lines of lauroside B (1), a megastigmane glycoside isolated from Laurus nobilis (bay laurel) leaves, was investigated...
  5. Lee S, Chung S, Lee S, Park W, Oh I, Mar W, et al. Acylated kaempferol glycosides from Laurus nobilis leaves and their inhibitory effects on Na+/K+-adenosine triphosphatase. Biol Pharm Bull. 2012;35:428-32 pubmed
    ..Through bioassay-guided separation of the leaf extract of Laurus nobilis, six acylated kaempferol glycosides (compounds 1-6) were isolated...
  6. Nayak S, Nalabothu P, Sandiford S, Bhogadi V, Adogwa A. Evaluation of wound healing activity of Allamanda cathartica. L. and Laurus nobilis. L. extracts on rats. BMC Complement Altern Med. 2006;6:12 pubmed
    Allamanda cathartica. L. is a perennial shrub used in traditional medicine for treating malaria and jaundice. Laurus nobilis. L. is a tree and has been used for its astringent, healing and diuretic properties...
  7. Fukuyama N, Ino C, Suzuki Y, Kobayashi N, Hamamoto H, Sekimizu K, et al. Antimicrobial sesquiterpenoids from Laurus nobilis L. Nat Prod Res. 2011;25:1295-303 pubmed publisher
    Activity-guided fractionations of leaf extracts from Laurus nobilis L. led to the isolation of a known sesquiterpene lactone, deacetyl laurenobiolide (1)...
  8. Conforti F, Statti G, Uzunov D, Menichini F. Comparative chemical composition and antioxidant activities of wild and cultivated Laurus nobilis L. leaves and Foeniculum vulgare subsp. piperitum (Ucria) coutinho seeds. Biol Pharm Bull. 2006;29:2056-64 pubmed
    The chemical composition and antioxidant activities of wild and cultivated Laurus nobilis leaves and Foeniculum vulgare subsp. piperitum seeds were determined. Differences were found in the total phenolic content of fennel...
  9. Caredda A, Marongiu B, Porcedda S, Soro C. Supercritical carbon dioxide extraction and characterization of Laurus nobilis essential oil. J Agric Food Chem. 2002;50:1492-6 pubmed
    Supercritical carbon dioxide extraction allowed essential oil of Laurus nobilis to be obtained. Extraction conditions were as follows: pressure, 90 bar; temperature, 50 degrees C; and carbon dioxide flow, Phi = 1.0 kg/h...
  10. Luna Herrera J, Costa M, González H, Rodrigues A, Castilho P. Synergistic antimycobacterial activities of sesquiterpene lactones from Laurus spp. J Antimicrob Chemother. 2007;59:548-52 pubmed
  11. Cho E, Lee S, Nam K, Shin J, Oh K, Kim K, et al. Amelioration of oxygen and glucose deprivation-induced neuronal death by chloroform fraction of bay leaves (Laurus nobilis). Biosci Biotechnol Biochem. 2010;74:2029-35 pubmed
    The purpose of this study was to determine whether the Laurus nobilis chloroform fraction (LNCF) protects against cerebral ischemia neuronal damage...
  12. Tilki F. Influence of pretreatment and desiccation on the germination of Laurus nobilis L. seeds. J Environ Biol. 2004;25:157-61 pubmed
    ..acid (GA3) in combination with cold-moist stratification and desiccation on the germination of bay laurel (Laurus nobilis L.) seeds were studied. It was found that the external fleshy pericarp caused dormancy...
  13. De Marino S, Borbone N, Zollo F, Ianaro A, Di Meglio P, Iorizzi M. Megastigmane and phenolic components from Laurus nobilis L. leaves and their inhibitory effects on nitric oxide production. J Agric Food Chem. 2004;52:7525-31 pubmed
    b>Laurus nobilis L. leaves are widely used in cooking and in folk medicine. Five new megastigmane glucosides (2-4, 7, and 9) named laurosides A-E and a new phenolic glucoside 12 were isolated from the methanolic extract of L. nobilis L...
  14. Dadalioglu I, Evrendilek G. Chemical compositions and antibacterial effects of essential oils of Turkish oregano (Origanum minutiflorum), bay laurel (Laurus nobilis), Spanish lavender (Lavandula stoechas L.), and fennel (Foeniculum vulgare) on common foodborne pathogens. J Agric Food Chem. 2004;52:8255-60 pubmed
    ..Schwarz & P. H. Davis), bay laurel (Laurus nobilis L.), Spanish lavender (Lavandula stoechas subsp. stoechas L.), and fennel (Foeniculum vulgare Mill...
  15. Kilic A, Hafizoglu H, Kollmannsberger H, Nitz S. Volatile constituents and key odorants in leaves, buds, flowers, and fruits of Laurus nobilis L. J Agric Food Chem. 2004;52:1601-6 pubmed
    The volatiles of fresh leaves, buds, flowers, and fruits from bay (Laurus nolilis L.) were isolated by solvent extraction and analyzed by capillary gas chromatography-mass spectrometry...
  16. Uchiyama N, Matsunaga K, Kiuchi F, Honda G, Tsubouchi A, Nakajima Shimada J, et al. Trypanocidal terpenoids from Laurus nobilis L. Chem Pharm Bull (Tokyo). 2002;50:1514-6 pubmed
    Trypanocidal constituents of dried leaves of Laurus nobilis L. (Lauraceae) were examined...
  17. Pacifico S, Gallicchio M, Lorenz P, Potenza N, Galasso S, Marciano S, et al. Apolar Laurus nobilis leaf extracts induce cytotoxicity and apoptosis towards three nervous system cell lines. Food Chem Toxicol. 2013;62:628-37 pubmed publisher
    In the course of a bioactivity screening of Mediterranean plants, the assessment of neuroprotective properties of Laurus nobilis L. was of interest. Dried leaves were extracted by sonication using CHCl3 as solvent...
  18. Yalçin H, Anik M, Sanda M, Cakir A. Gas chromatography/mass spectrometry analysis of Laurus nobilis essential oil composition of northern Cyprus. J Med Food. 2007;10:715-9 pubmed
    The chemical composition of the essential oil isolated from the leaves of the Laurus nobilis plant (from the Northern Cyprus Mountains) by hydrodistillation was analyzed by gas chromatography-mass spectrometry...
  19. Liu M, Otsuka N, Noyori K, Shiota S, Ogawa W, Kuroda T, et al. Synergistic effect of kaempferol glycosides purified from Laurus nobilis and fluoroquinolones on methicillin-resistant Staphylococcus aureus. Biol Pharm Bull. 2009;32:489-92 pubmed
    In a previous study, we reported that two kaempferol glycosides isolated from Laurus nobilis L...
  20. Ozcan B, Esen M, Sangun M, Coleri A, Caliskan M. Effective antibacterial and antioxidant properties of methanolic extract of Laurus nobilis seed oil. J Environ Biol. 2010;31:637-41 pubmed
    ..and antioxidant activities of the essential oil, seed oil, and methanolic extract of seed oil obtained from Laurus nobilis L. (Lauraceae)...
  21. Sangun M, Aydin E, Timur M, Karadeniz H, Caliskan M, Ozkan A. Comparison of chemical composition of the essential oil of Laurus nobilis L. leaves and fruits from different regions of Hatay, Turkey. J Environ Biol. 2007;28:731-3 pubmed
    The essential oils of the leaves and fruits from bay (Laurus nobilis L...
  22. Dalĺ Acqua S, Cervellati R, Speroni E, Costa S, Guerra M, Stella L, et al. Phytochemical composition and antioxidant activity of Laurus nobilis L. leaf infusion. J Med Food. 2009;12:869-76 pubmed publisher
    b>Laurus nobilis L. (laurel) leaves are frequently used as a spice for cooking purposes. Folk medicine in many countries uses the infusion of the plant in stomachic and carminative remedies, as well as for the treatment of gastric diseases...
  23. Speroni E, Cervellati R, Dalĺ Acqua S, Guerra M, Greco E, Govoni P, et al. Gastroprotective effect and antioxidant properties of different Laurus nobilis L. leaf extracts. J Med Food. 2011;14:499-504 pubmed publisher
    b>Laurus nobilis L. (Family Lauraceae) is an evergreen tree widely distributed in the Mediterranean area and Europe...
  24. De Marino S, Borbone N, Zollo F, Ianaro A, Di Meglio P, Iorizzi M. New sesquiterpene lactones from Laurus nobilis leaves as inhibitors of nitric oxide production. Planta Med. 2005;71:706-10 pubmed
    ..2) have been isolated from the methanolic extract of Laurus nobilis L. leaves...
  25. Oddo E, Inzerillo S, La Bella F, Grisafi F, Salleo S, Nardini A. Short-term effects of potassium fertilization on the hydraulic conductance of Laurus nobilis L. Tree Physiol. 2011;31:131-8 pubmed publisher
    ..Our data provide additional support for the important role of potassium nutrition in agriculture and forestry...
  26. Kang H, Yu K, Jun W, Chang I, Han S, Kim H, et al. Isolation and characterization of alkyl peroxy radical scavenging compound from leaves of Laurus nobilis. Biol Pharm Bull. 2002;25:102-8 pubmed
    EtOH-soluble fraction from leaves of Laurus nobilis (bay leaves) possessed the highest alkyl peroxy radical (ROO*) scavenging activity among 120 kinds of herbs and edible plants, using the bioassay system which could determine the ..
  27. Andrade Ochoa S, Sánchez Aldana D, Chacón Vargas K, Rivera Chavira B, Sánchez Torres L, Camacho A, et al. Oviposition Deterrent and Larvicidal and Pupaecidal Activity of Seven Essential Oils and their Major Components against Culex quinquefasciatus Say (Diptera: Culicidae): Synergism-antagonism Effects. Insects. 2018;9: pubmed publisher
    ..Merr. & L.M.Perry), laurel (Laurusnobilis Linnaeus), Mexican oregano (Lippiaberlandieri Schauer) and anise (Pimpinella..
  28. Kazemian H, Ghafourian S, Heidari H, Amiri P, Yamchi J, Shavalipour A, et al. Antibacterial, anti-swarming and anti-biofilm formation activities of Chamaemelum nobile against Pseudomonas aeruginosa. Rev Soc Bras Med Trop. 2015;48:432-6 pubmed publisher
    ..Extracts from different plant parts such as the leaves, flowers, fruit, and bark of Combretum albiflorum, Laurus nobilis , and Sonchus oleraceus were found to possess anti-quorum sensing (QS) activities...
  29. Sayyah M, Saroukhani G, Peirovi A, Kamalinejad M. Analgesic and anti-inflammatory activity of the leaf essential oil of Laurus nobilis Linn. Phytother Res. 2003;17:733-6 pubmed
    The leaf essential oil of Laurus nobilis Linn. (Lauraceae) has been evaluated for antinociceptive and anti-inflammatory activities in mice and rats...
  30. Teke M, Sezginturk M, Dinckaya E. A biosensor based on Bay leaf (Laurus nobilis L.) tissue homogenate: improvement of the stability characteristics by a simple bio-imprinted technique. Artif Cells Blood Substit Immobil Biotechnol. 2008;36:445-56 pubmed publisher
    ..In this study, a bio-imprinted Bay leaf (Laurus nobilis L.) tissue homogenate biosensor was devised by a very simple way...
  31. Komiya T, Yamada Y, Moteki H, Katsuzaki H, Imai K, Hibasami H. Hot water soluble sesquiterpenes [anhydroperoxy-costunolide and 3-oxoeudesma-1,4(15),11(13)triene-12,6alpha-olide] isolated from laurel (Laurus nobilis L.) induce cell death and morphological change indicative of apoptotic chromatin condensation in l. Oncol Rep. 2004;11:85-8 pubmed
    ..anhydroperoxycostunolide and 3-oxo-eudesma-1,4(15),11(13)triene-12,6alpha-olide] were purified from Laurel (Laurus nobilis L.) and identified by Mass, and 1H- and 13C-NMR...
  32. Trifilò P, Casolo V, Raimondo F, Petrussa E, Boscutti F, Lo Gullo M, et al. Effects of prolonged drought on stem non-structural carbohydrates content and post-drought hydraulic recovery in Laurus nobilis L.: The possible link between carbon starvation and hydraulic failure. Plant Physiol Biochem. 2017;120:232-241 pubmed publisher
    ..Our data suggest that plant carbon status might indirectly influence plant performance during and after drought via effects on xylem hydraulic functioning, supporting the view of a possible mechanistic link between the two processes. ..
  33. Raman V, Bussmann R, Khan I. Which Bay Leaf is in Your Spice Rack? - A Quality Control Study. Planta Med. 2017;83:1058-1067 pubmed publisher
    ..The true "bay leaf", also known as "bay laurel" or "sweet bay", is sourced from the tree Laurus nobilis, a native of the Mediterranean region...
  34. Caputo L, Nazzaro F, Souza L, Aliberti L, De Martino L, Fratianni F, et al. Laurus nobilis: Composition of Essential Oil and Its Biological Activities. Molecules. 2017;22: pubmed publisher
    i>Laurus nobilis is native to the southern Mediterranean region and cultivated mainly in Europe and the USA as an ornamental and medicinal plant. The chemical composition of the essential oil (EO) from leaves of L...
  35. Nardini A, Savi T, Losso A, Petit G, Pacilè S, Tromba G, et al. X-ray microtomography observations of xylem embolism in stems of Laurus nobilis are consistent with hydraulic measurements of percentage loss of conductance. New Phytol. 2017;213:1068-1075 pubmed publisher
    ..We measured the percentage loss of conductance (PLC) of excised stems of Laurus nobilis (laurel) dehydrated to different xylem pressures, and compared results with direct observation of gas-..
  36. Yahyaa M, Matsuba Y, Brandt W, Doron Faigenboim A, Bar E, McClain A, et al. Identification, Functional Characterization, and Evolution of Terpene Synthases from a Basal Dicot. Plant Physiol. 2015;169:1683-97 pubmed publisher
    Bay laurel (Laurus nobilis) is an agriculturally and economically important dioecious tree in the basal dicot family Lauraceae used in food and drugs and in the cosmetics industry...
  37. Teixeira T, Rosa J, Rainha N, Baptista J, Rodrigues A. Assessment of molluscicidal activity of essential oils from five Azorean plants against Radix peregra (Müller, 1774). Chemosphere. 2012;87:1-6 pubmed publisher
    The molluscicidal activity of essential oils from two endemic (Juniperus brevifolia; Laurus azorica) and three introduced (Hedychium gardnerianum; Pittosporum undulatum; Psidium cattleianum) Azorean plants against the snail Radix peregra ..
  38. Bouaziz A, Salido S, Linares Palomino P, Sanchez A, Altarejos J, Bartegi A, et al. Cinnamtannin B-1 from bay wood reduces abnormal intracellular Ca2+ homeostasis and platelet hyperaggregability in type 2 diabetes mellitus patients. Arch Biochem Biophys. 2007;457:235-42 pubmed
    ..We conclude that cinnamtannin B-1 exerts an effective antioxidant action in platelets from patients with type 2 diabetes mellitus and reverses the enhanced Ca2+ mobilization and hyperaggregability. ..
  39. Rafiq R, Hayek S, Anyanwu U, Hardy B, Giddings V, Ibrahim S, et al. Antibacterial and Antioxidant Activities of Essential Oils from Artemisia herba-alba Asso., Pelargonium capitatum × radens and Laurus nobilis L. Foods. 2016;5: pubmed publisher
  40. Peixoto L, Rosalen P, Ferreira G, Freires I, de Carvalho F, Castellano L, et al. Antifungal activity, mode of action and anti-biofilm effects of Laurus nobilis Linnaeus essential oil against Candida spp. Arch Oral Biol. 2017;73:179-185 pubmed publisher
    The present study demonstrated the antifungal potential of the chemically characterized essential oil (EO) of Laurus nobilis L. (bay laurel) against Candida spp...
  41. Papageorgiou V, Mallouchos A, Komaitis M. Investigation of the antioxidant behavior of air- and freeze-dried aromatic plant materials in relation to their phenolic content and vegetative cycle. J Agric Food Chem. 2008;56:5743-52 pubmed publisher
    ..Extracts from air-dried Laurus nobilis L...
  42. Matsuda H, Shimoda H, Ninomiya K, Yoshikawa M. Inhibitory mechanism of costunolide, a sesquiterpene lactone isolated from Laurus nobilis, on blood-ethanol elevation in rats: involvement of inhibition of gastric emptying and increase in gastric juice secretion. Alcohol Alcohol. 2002;37:121-7 pubmed
    ..In conclusion, the inhibitory effects of costunolide and alpha-MGBL on blood-ethanol elevation were based on inhibition of gastric emptying and dilution of the ethanol concentration by the increased gastric fluid. ..
  43. Ozcan M, Chalchat J. Effect of different locations on the chemical composition of essential oils of laurel (Laurus nobilis L.) leaves growing wild in Turkey. J Med Food. 2005;8:408-11 pubmed
    The essential oil components of Laurus nobilis gathered from seven different locations of Turkey were identified by gas chromatography/mass spectrometry. The oil yields on a dry weight basis ranged between 1.4% to 2.6%...
  44. Casamassima D, Chiosi F, Vizzarri F, Palazzo M, Costagliola C. The effect of Laurus nobilis on the blood and lenses antioxidant activity in rabbit under fat-enriched diet. Physiol Res. 2017;66:325-333 pubmed
    Fat-enriched diet is strongly associated with cataract development. Laurus nobilis shows antioxidant activity...
  45. Mazzio E, Bauer D, Mendonça P, Taka E, Soliman K. Natural product HTP screening for attenuation of cytokine-induced neutrophil chemo attractants (CINCs) and NO2- in LPS/IFNγ activated glioma cells. J Neuroimmunol. 2017;302:10-19 pubmed publisher
    ..Tansy (Tanacetum vulgare), Maddar Root (Rubia tinctoria), Red Sandle wood (Pterocarpus santalinus), Bay Leaf (Laurus nobilis, Lauraceae), quercetin, cardamonin, fisetin, EGCG, biochanin A, galangin, apigenin and curcumin...
  46. Vijayakumar S, Vaseeharan B, Malaikozhundan B, Shobiya M. Laurus nobilis leaf extract mediated green synthesis of ZnO nanoparticles: Characterization and biomedical applications. Biomed Pharmacother. 2016;84:1213-1222 pubmed publisher
    The present study reports the green synthesis of zinc oxide nanoparticles using the aqueous leaf extract of Laurus nobilis (Ln-ZnO NPs) by co-precipitation method...
  47. Suganthi R, Rajamani S, Ravichandran M, Anuradha C. Effect of food seasoning spices mixture on biomarkers of oxidative stress in tissues of fructose-fed insulin-resistant rats. J Med Food. 2007;10:149-53 pubmed
    ..The positive effect of SM on the oxidant-antioxidant balance could be attributed to the active constituents of the different spices present in the mixture...
  48. Tinoco M, Ramos P, Candeias M. Effects of a hexane extract from Laurus novocanariensis leaves on the ethanol metabolism of Wistar rats. Fitoterapia. 2009;80:130-3 pubmed publisher
    A hexane extract from the leaves of Laurus novocanariensis was investigated for its activity on ethanol metabolism in Wistar rats...
  49. Mazzio E, Li N, Bauer D, Mendonça P, Taka E, Darb M, et al. Natural product HTP screening for antibacterial (E.coli 0157:H7) and anti-inflammatory agents in (LPS from E. coli O111:B4) activated macrophages and microglial cells; focus on sepsis. BMC Complement Altern Med. 2016;16:467 pubmed
    ..demonstrate relative few valid hits with anti-inflammatory effects at < 250?g/ml for the following: Bay Leaf (Laurus nobilis), Elecampagne Root (Inula helenium), Tansy (Tanacetum vulgare),Yerba (Eriodictyon californicum) and ..
  50. Díaz Maroto M, Pérez Coello M, Cabezudo M. Effect of drying method on the volatiles in bay leaf (Laurus nobilis L.). J Agric Food Chem. 2002;50:4520-4 pubmed
    The effect of different drying treatments on the volatiles in bay leaf (Laurus nobilis L.) was studied...
  51. Uysal B, Sozmen F, Buyuktas B. Solvent-free microwave extraction of essential oils from Laurus nobilis and Melissa officinalis: comparison with conventional hydro-distillation and ultrasound extraction. Nat Prod Commun. 2010;5:111-4 pubmed
    ..and Laurus nobilis L...
  52. Jeter S, McDermott C, Bower P, Kinzelman J, Bootsma M, Goetz G, et al. Bacteroidales diversity in ring-billed gulls (Laurus delawarensis) residing at Lake Michigan beaches. Appl Environ Microbiol. 2009;75:1525-33 pubmed publisher
  53. Ferrari B, Castilho P, Tomi F, Rodrigues A, do Ceu Costa M, Casanova J. Direct identification and quantitative determination of costunolide and dehydrocostuslactone in the fixed oil of Laurus novocanariensis by 13C-NMR spectroscopy. Phytochem Anal. 2005;16:104-7 pubmed
    The fixed oil of Laurus novocanariensis (previously L. azorica) contains mostly glycerides together with minor non-saponifiable compounds...
  54. Espino S, Schenk H. Mind the bubbles: achieving stable measurements of maximum hydraulic conductivity through woody plant samples. J Exp Bot. 2011;62:1119-32 pubmed publisher
    ..Prehydrated woody stems from Laurus nobilis (Lauraceae) and Encelia farinosa (Asteraceae) collected from plants grown in the Fullerton Arboretum in ..
  55. Ben Amor N, Bouaziz A, Romera Castillo C, Salido S, Linares Palomino P, Bartegi A, et al. Characterization of the intracellular mechanisms involved in the antiaggregant properties of cinnamtannin B-1 from bay wood in human platelets. J Med Chem. 2007;50:3937-44 pubmed
    Cinnamtannin B-1, a natural A-type proanthocyanidin recently identified as a radical scavenger component of Laurus nobilis L., exerts antiaggregant and antiapoptotic effects in human platelets...
  56. Misharina T, Polshkov A. [Antioxidant properties of essential oils: autoxidation of essential oils from laurel and fennel and effects of mixing with essential oil from coriander]. Prikl Biokhim Mikrobiol. 2005;41:693-702 pubmed
    Changes in the composition of essential oils from the seeds of laurel (Laurus nobilis L.) and fennel (Foeniculum vulgare Mill., var...
  57. Erler F, Ulug I, Yalcinkaya B. Repellent activity of five essential oils against Culex pipiens. Fitoterapia. 2006;77:491-4 pubmed
    ..camaldulensis), dried foliage of mint (Mentha piperita) and basil (Ocimum basilicum) and fresh foliage of laurel (Laurus nobilis) were tested for their repellency against the adult females of Culex pipiens...
  58. Teke M, Sezginturk M, Dinckaya E. Sulfite determination by a biosensor based on bay leaf tissue homogenate: very simple and economical method. Artif Cells Blood Substit Immobil Biotechnol. 2009;37:138-42 pubmed publisher
    ..The biosensor showed a linear calibration graph in the range of 25-100 microM sulfite. The biosensor presents a very simple, economical, reliable, and feasible method for sulfite detection in foods. ..
  59. Lee T, Lee S, Ho Kim K, Oh K, Shin J, Mar W. Effects of magnolialide isolated from the leaves of Laurus nobilis L. (Lauraceae) on immunoglobulin E-mediated type I hypersensitivity in vitro. J Ethnopharmacol. 2013;149:550-6 pubmed publisher
    b>Laurus nobilis L. (Lauraceae) has been used for folk medicines in the Mediterranean area and Europe to treat various disorders including skin inflammation (dermatitis) and asthma...
  60. Bozkurt M, Selek N, Küçükyilmaz K, Eren H, Guven E, Catli A, et al. Effects of dietary supplementation with a herbal extract on the performance of broilers infected with a mixture of Eimeria species. Br Poult Sci. 2012;53:325-32 pubmed publisher
    ..5. These results indicate that providing a herbal extract in the diet was not as effective as monensin in protecting broilers exposed to a coccidial challenge. ..
  61. Rivera Barreno R, del Castillo Vaquero A, Salido G, Gonzalez A. Effect of cinnamtannin B-1 on cholecystokinin-8-evoked responses in mouse pancreatic acinar cells. Clin Exp Pharmacol Physiol. 2010;37:980-8 pubmed publisher
  62. Hibasami H, Yamada Y, Moteki H, Katsuzaki H, Imai K, Yoshioka K, et al. Sesquiterpenes (costunolide and zaluzanin D) isolated from laurel (Laurus nobilis L.) induce cell death and morphological change indicative of apoptotic chromatin condensation in leukemia HL-60 cells. Int J Mol Med. 2003;12:147-51 pubmed
    Sesquiterpenes (costunolide and zaluzanin D) were purified from laurel (Laurus nobilis L.) and identified by Mass, and 1H- and 13C-NMR...
  63. Bernal M, Llorens L, Badosa J, Verdaguer D. Interactive effects of UV radiation and water availability on seedlings of six woody Mediterranean species. Physiol Plant. 2013;147:234-47 pubmed publisher
    ..Species-specific responses to UV were not related with the xerophytic or mesophytic character of the studied species...
  64. Ozcan M. Effect of some essential oils on rheological properties of wheat flour dough. Int J Food Sci Nutr. 2009;60:176-81 pubmed publisher
    ..pickling herb (Echinophora tenuifolia L.) and laurel (Laurus nobilis L.) essential oils on extensograph and farinograph characteristics of wheat flour doughs were determined...
  65. Marzouki H, Khaldi A, Chamli R, Bouzid S, Piras A, Falconieri D, et al. Biological activity evaluation of the oils from Laurus nobilis of Tunisia and Algeria extracted by supercritical carbon dioxide. Nat Prod Res. 2009;23:230-7 pubmed publisher
    Isolation of essential oil from dried and ground leaves of Laurus nobilis L...
  66. del Hierro A, Kronberger W, Hietz P, Offenthaler I, Richter H. A new method to determine the oxygen concentration inside the sapwood of trees. J Exp Bot. 2002;53:559-63 pubmed
    ..5% in the morning next day). In a greenhouse experiment the sapwood oxygen concentration of Laurus nobilis could be influenced by flooding the root system. The very fast response, high resolution (better than 0...
  67. Turkez H, Toğar B. Aluminum phosphide-induced genetic and oxidative damages in rats: attenuation by Laurus nobilis leaf extract. Toxicol Ind Health. 2013;29:579-83 pubmed publisher
    ..Therefore, this study was aimed to evaluate the effect of Laurus nobilis (L) leaf extract (LNE) against AlP-induced genetic and oxidative damages in rats...
  68. Kaurinovic B, Popovic M, Vlaisavljevic S. In vitro and in vivo effects of Laurus nobilis L. leaf extracts. Molecules. 2010;15:3378-90 pubmed publisher
    ..Combined treatments with CCl(4) and the examined extracts showed both positive and negative synergism. Based on the experimental results, the strongest protective effect was shown by the EtOAc extract...
  69. Jin S, Hong J, Jung S, Cho K. Turmeric and laurel aqueous extracts exhibit in vitro anti-atherosclerotic activity and in vivo hypolipidemic effects in a zebrafish model. J Med Food. 2011;14:247-56 pubmed publisher
    ..Consumption of turmeric and laurel extracts exhibited hypolipidemic and antioxidant activities in a hypercholesterolemic zebrafish model...
  70. Zaragotas D, Anastassopoulos E. Uniformity trials in plant freezing assays involving microtitre plates. Cryo Letters. 2011;32:21-7 pubmed
    ..b>Laurus nobilis leaf strips were used as experimental material...
  71. Gómez Coronado D, Barbas C. Optimized and validated HPLC method for alpha- and gamma-tocopherol measurement in Laurus nobilis leaves. New data on tocopherol content. J Agric Food Chem. 2003;51:5196-201 pubmed
    Extraction and chromatographic conditions for measuring tocopherols from Laurus nobilis were optimized...
  72. Flamini G, Tebano M, Cioni P, Ceccarini L, Ricci A, Longo I. Comparison between the conventional method of extraction of essential oil of Laurus nobilis L. and a novel method which uses microwaves applied in situ, without resorting to an oven. J Chromatogr A. 2007;1143:36-40 pubmed
    ..An insulated microwave coaxial antenna was introduced inside a 1000 ml glass flask containing dry Laurus nobilis L. leaves and tap water...
  73. Turkez H, Toğar B. Aluminium phosphide-induced genetic and oxidative damages in vitro: attenuation by Laurus nobilis L. leaf extract. Indian J Pharmacol. 2013;45:71-5 pubmed publisher
    The present investigation was undertaken to assess the protective effect of Laurus nobilis leaf extract (LNE) against aluminum phosphide (AIP)-induced genotoxic and oxidative damages stress in cultured human blood cells in the presence of ..
  74. Bennett L, Abeywardena M, Burnard S, Forsyth S, Head R, King K, et al. Molecular size fractions of bay leaf (Laurus nobilis) exhibit differentiated regulation of colorectal cancer cell growth in vitro. Nutr Cancer. 2013;65:746-64 pubmed publisher
    ..ingredients and report results on potential colon cancer-regulating properties of processed forms of Bay leaf (Laurus nobilis)...
  75. Chaudhry N, Tariq P. Bactericidal activity of black pepper, bay leaf, aniseed and coriander against oral isolates. Pak J Pharm Sci. 2006;19:214-8 pubmed
    ..bay leaf (Laurus nobilis L.), aniseed (Pimpinella anisum L.), and coriander (Coriandum sativum L...
  76. Kilic A, Kollmannsberger H, Nitz S. Glycosidically bound volatiles and flavor precursors in Laurus nobilis L. J Agric Food Chem. 2005;53:2231-5 pubmed
    Glycosidically bound volatile compounds in different parts (leaves and buds) of Laurus nobilis L. were investigated...
  77. Matsubara E, Fukagawa M, Okamoto T, Fukuda A, Hayashi C, Ohnuki K, et al. Volatiles emitted from the leaves of Laurus nobilis L. improve vigilance performance in visual discrimination task. Biomed Res. 2011;32:19-28 pubmed
    The leaves of Laurus noblis L. (laurel) are mainly used as a spice in cooking, and the essential oil obtained by steam distillation of the leaves is used as an additive in foods, drugs and cosmetics...
  78. Erkmen O, Ozcan M. Antimicrobial effects of Turkish propolis, pollen, and laurel on spoilage and pathogenic food-related microorganisms. J Med Food. 2008;11:587-92 pubmed publisher
    The antimicrobial activities of propolis extract, pollen extract, and essential oil of laurel (Laurus nobilis L.) at concentrations from 0.02% to 2...
  79. Dalĺ Acqua S, Viola G, Giorgetti M, Loi M, Innocenti G. Two new sesquiterpene lactones from the leaves of Laurus nobilis. Chem Pharm Bull (Tokyo). 2006;54:1187-9 pubmed
    As a part of our ongoing interest in new bioactive compounds from natural sources, we studied Laurus nobilis (Lauraceae). This plant is widespread in the Mediterranean area and is used for medicinal and economic purposes...
  80. Ndeffo Mbah M, Gilligan C. Balancing detection and eradication for control of epidemics: sudden oak death in mixed-species stands. PLoS ONE. 2010;5:e12317 pubmed publisher
    ..The results hold when quarantine is introduced to reduce the ingress of infected material into the region of interest...
  81. Bañares A, Beltrán E, Bon M. Gerronema wildpretii sp. nov. (Agaricales, Basidiomycetes) a new species from the Canary Islands. Mycologia. 2006;98:455-9 pubmed
    ..Gerronema wildpretii, collected in climactic sites of the monteverde forest of the Canary Islands is described and illustrated. Its macro- and microscopic features delimit this taxon as a new species...
  82. Al Haidari R, Shaaban M, Ibrahim S, Mohamed G. ANTI-QUORUM SENSING ACTIVITY OF SOME MEDICINAL PLANTS. Afr J Tradit Complement Altern Med. 2016;13:67-71 pubmed publisher
    ..The aim of this study was to explore the effect of the extracts from some medicinal plants on quorum sensing and related virulence factors of P. aeruginosa...
  83. Puoci F, Cirillo G, Curcio M, Iemma F, Spizzirri U, Picci N. Molecularly imprinted solid phase extraction for the selective HPLC determination of alpha-tocopherol in bay leaves. Anal Chim Acta. 2007;593:164-70 pubmed
    ..16x10(-6) mol L(-1), respectively, as well as good precision (intraday precision below 3.3% and interday precisions below 6.5%) and recovery (60%). Thus, it can be successfully used for the purification of alpha-TP from bay leaves...
  84. Esteban R, Jimenez M, Morales D, Jiménez E, Hormaetxe K, Becerril J, et al. Short- and long-term modulation of the lutein epoxide and violaxanthin cycles in two species of the Lauraceae: sweet bay laurel (Laurus nobilis L.) and avocado (Persea americana Mill.). Plant Biol (Stuttg). 2008;10:288-97 pubmed publisher
    ..of the violaxanthin (V) and lutein epoxide (Lx) cycles were studied in two species of Lauraceae: sweet bay laurel (Laurus nobilis L.) and avocado (Persea americana L.)...
  85. Turkez H, Geyikoglu F. The effect of laurel leaf extract against toxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in cultured rat hepatocytes. Arh Hig Rada Toksikol. 2011;62:309-15 pubmed publisher
    ..Added to TCDD, laurel countered its toxic effects and showed protective effects against TCDD-mediated DNA damage. This points to the therapeutic potential of laurel against TCDD toxicity in the liver...
  86. Damiani N, Fernández N, Porrini M, Gende L, Alvarez E, Buffa F, et al. Laurel leaf extracts for honeybee pest and disease management: antimicrobial, microsporicidal, and acaricidal activity. Parasitol Res. 2014;113:701-9 pubmed publisher
    ..In this research, different Laurus nobilis extracts are tested against the main honeybee pests through an integrated point of view...
  87. Kivcak B, Mert T. Preliminary evaluation of cytotoxic properties of Laurus nobilis leaf extracts. Fitoterapia. 2002;73:242-3 pubmed
    n-Hexane, ethanol and water extracts of Laurus nobilis L. leaves were evaluated for cytotoxic properties using the Brine shrimp bioassay. Only the n-hexane extract exhibited cytotoxic activity.
  88. Qnais E, Abdulla F, Kaddumi E, Abdalla S. Antidiarrheal activity of Laurus nobilis L. leaf extract in rats. J Med Food. 2012;15:51-7 pubmed publisher
    In Jordan, the leaves of Laurus nobilis (Family Lauraceae) have been used in folk medicine for the treatment of diarrhea, among other ailments. However, the ethnopharmacology of this plant needs to be scientifically validated...
  89. Koo U, Nam K, Ham A, Lyu D, Kim B, Lee S, et al. Neuroprotective effects of 3?-acetoxyeudesma-1,4(15),11(13)-trien-12,6?-olide against dopamine-induced apoptosis in the human neuroblastoma SH-SY5Y cell line. Neurochem Res. 2011;36:1991-2001 pubmed publisher
    ..the inhibitory effects of 3?-acetoxyeudesma-1,4(15),11(13)-trien-12,6?-olide (AETO), purified from the leaves of Laurus nobilis L., on DA-induced apoptosis and ?-synuclein (?-syn) formation in dopaminergic SH-SY5Y cells...
  90. Ozturk I, Tornuk F, Sagdic O, Kisi O. Application of non-linear models to predict inhibition effects of various plant hydrosols on Listeria monocytogenes inoculated on fresh-cut apples. Foodborne Pathog Dis. 2012;9:607-16 pubmed publisher
    ..monocytogenes counts. The ANN model was also effective; the MLR model was found to be poor at estimating L. monocytogenes numbers...
  91. Nuyttens D, Braekman P, Foque D. Optimization of the spray application technology in bay laurel (Laurus nobilis). Commun Agric Appl Biol Sci. 2009;74:85-90 pubmed
    ..With this automated tunnel system, it is possible to obtain a good spray result in combination with an increase in the productivity and a reduction in operator exposure...