cinnamomum zeylanicum

Summary

Summary: The tree which is known for its bark which is sold as cinnamon. The oil contains about 65-80% cinnamaldehyde and 10% EUGENOL and many TERPENES.

Top Publications

  1. Verspohl E, Bauer K, Neddermann E. Antidiabetic effect of Cinnamomum cassia and Cinnamomum zeylanicum in vivo and in vitro. Phytother Res. 2005;19:203-6 pubmed
    ..The elevation in plasma insulin was direct since a stimulatory in vitro effect of insulin release from INS-1 cells (an insulin secreting cell line) was observed. Thus the cassia extract has a direct antidiabetic potency...
  2. Yang Y, Lee H, Lee S, Clark J, Ahn Y. Ovicidal and adulticidal activities of Cinnamomum zeylanicum bark essential oil compounds and related compounds against Pediculus humanus capitis (Anoplura: Pediculicidae). Int J Parasitol. 2005;35:1595-600 pubmed
    The toxicity of cinnamon, Cinnamomum zeylanicum, bark essential oil compounds against eggs and adult females of human head louse, Pediculus humanus capitis, was examined using direct contact and vapour phase toxicity bioassays and ..
  3. Becerril R, Gomez Lus R, Goñi P, Lopez P, Nerin C. Combination of analytical and microbiological techniques to study the antimicrobial activity of a new active food packaging containing cinnamon or oregano against E. coli and S. aureus. Anal Bioanal Chem. 2007;388:1003-11 pubmed
    ..After an extraction from dead cells, cinnamaldehyde was detected by GC-MS in E. coli exposed to the active packaging containing cinnamon. ..
  4. Qin B, Nagasaki M, Ren M, Bajotto G, Oshida Y, Sato Y. Cinnamon extract (traditional herb) potentiates in vivo insulin-regulated glucose utilization via enhancing insulin signaling in rats. Diabetes Res Clin Pract. 2003;62:139-48 pubmed
    ..These results suggest that the cinnamon extract would improve insulin action via increasing glucose uptake in vivo, at least in part through enhancing the insulin-signaling pathway in skeletal muscle...
  5. Chericoni S, Prieto J, Iacopini P, Cioni P, Morelli I. In vitro activity of the essential oil of Cinnamomum zeylanicum and eugenol in peroxynitrite-induced oxidative processes. J Agric Food Chem. 2005;53:4762-5 pubmed
    The essential oil obtained from the bark of Cinnamomum zeylanicum Blume (Lauraceae) and three of its main components, eugenol, (E)-cinnamaldehyde, and linalool (representing 82...
  6. Benarroz M, Fonseca A, Rocha G, Frydman J, Rocha V, Pereira M, et al. Cinnamomum zeylanicum extract on the radiolabelling of blood constituents and the morphometry of red blood cells: in vitro assay. Appl Radiat Isot. 2008;66:139-46 pubmed
    Effects of Cinnamomum zeylanicum (cinnamon) on the labelling of blood constituents with technetium-99m(99mTc) and on the morphology of red blood cells were studied...
  7. Anderson R, Broadhurst C, Polansky M, Schmidt W, Khan A, Flanagan V, et al. Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity. J Agric Food Chem. 2004;52:65-70 pubmed
    ..These polyphenolic polymers found in cinnamon may function as antioxidants, potentiate insulin action, and may be beneficial in the control of glucose intolerance and diabetes...
  8. Kim S, Hyun S, Choung S. Anti-diabetic effect of cinnamon extract on blood glucose in db/db mice. J Ethnopharmacol. 2006;104:119-23 pubmed
  9. Schoene N, Kelly M, Polansky M, Anderson R. Water-soluble polymeric polyphenols from cinnamon inhibit proliferation and alter cell cycle distribution patterns of hematologic tumor cell lines. Cancer Lett. 2005;230:134-40 pubmed
    ..The results suggest the potential of CE to interact with phosphorylation/dephosphorylation signaling activities to reduce cellular proliferation in tandem with a block at the G2/M phase of the cell cycle...

More Information

Publications106 found, 100 shown here

  1. Cao H, Polansky M, Anderson R. Cinnamon extract and polyphenols affect the expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3T3-L1 adipocytes. Arch Biochem Biophys. 2007;459:214-22 pubmed
    ..These results suggest that cinnamon exhibits the potential to increase the amount of proteins involved in insulin signaling, glucose transport, and anti-inflammatory/anti-angiogenesis response...
  2. Solomon T, Blannin A. Effects of short-term cinnamon ingestion on in vivo glucose tolerance. Diabetes Obes Metab. 2007;9:895-901 pubmed
    ..In vivo study shows that cinnamon may have beneficial effects on glucose homeostasis; therefore the aim of this study was to further investigate this phenomenon in humans...
  3. Shahverdi A, Monsef Esfahani H, Tavasoli F, Zaheri A, Mirjani R. Trans-cinnamaldehyde from Cinnamomum zeylanicum bark essential oil reduces the clindamycin resistance of Clostridium difficile in vitro. J Food Sci. 2007;72:S055-8 pubmed
    ..The essential oil of Cinnamomum zeylanicum bark enhanced the bactericidal activity of clindamycin and decreased the minimum inhibitory concentration ..
  4. Panickar K, Polansky M, Anderson R. Cinnamon polyphenols attenuate cell swelling and mitochondrial dysfunction following oxygen-glucose deprivation in glial cells. Exp Neurol. 2009;216:420-7 pubmed publisher
    ..Our results show that CPE reduces OGD-induced cell swelling as well as the decline in DeltaPsi(m) in cultures and some of its protective effects may be through inhibiting the mPT...
  5. Smitha S, Philip D, Gopchandran K. Green synthesis of gold nanoparticles using Cinnamomum zeylanicum leaf broth. Spectrochim Acta A Mol Biomol Spectrosc. 2009;74:735-9 pubmed publisher
    ..The synthesis of gold nanoparticles using Cinnamomum zeylanicum leaf broth as the reducing agent is reported...
  6. Woehrlin F, Fry H, Abraham K, Preiss Weigert A. Quantification of flavoring constituents in cinnamon: high variation of coumarin in cassia bark from the German retail market and in authentic samples from indonesia. J Agric Food Chem. 2010;58:10568-75 pubmed publisher
    ..Interestingly, a high variation was observed in one of the trees, whereas no coumarin was detected in the samples of two other trees. In conclusion, coumarin levels in cassia cinnamon can vary widely even within a single tree...
  7. Guerra F, Mendes J, Sousa J, Morais Braga M, Santos B, Melo Coutinho H, et al. Increasing antibiotic activity against a multidrug-resistant Acinetobacter spp by essential oils of Citrus limon and Cinnamomum zeylanicum. Nat Prod Res. 2012;26:2235-8 pubmed publisher
    ..The Essential oil of Cinnamomum zeylanicum (EOCZ) addition at 78...
  8. Jarvill Taylor K, Anderson R, Graves D. A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes. J Am Coll Nutr. 2001;20:327-36 pubmed
    ..These studies investigated the ability of a hydroxychalcone from cinnamon to function as an insulin mimetic in 3T3-LI adipocytes...
  9. Oussalah M, Caillet S, Lacroix M. Mechanism of action of Spanish oregano, Chinese cinnamon, and savory essential oils against cell membranes and walls of Escherichia coli O157:H7 and Listeria monocytogenes. J Food Prot. 2006;69:1046-55 pubmed
    ..monocytogenes. Electronic microscopy observations revealed that the cell membrane of both treated bacteria was significantly damaged. These results suggest that the cytoplasmic membrane is involved in the toxic action of essential oils...
  10. Hlebowicz J, Darwiche G, Björgell O, Almér L. Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects. Am J Clin Nutr. 2007;85:1552-6 pubmed
    ..Previous studies of patients with type 2 diabetes showed that cinnamon lowers fasting serum glucose, triacylglycerol, and LDL- and total cholesterol concentrations...
  11. Marongiu B, Piras A, Porcedda S, Tuveri E, Sanjust E, Meli M, et al. Supercritical CO2 extract of Cinnamomum zeylanicum: chemical characterization and antityrosinase activity. J Agric Food Chem. 2007;55:10022-7 pubmed
    The volatile oil of the bark of Cinnamomum zeylanicum was extracted by means of supercritical CO2 fluid extraction in different conditions of pressure and temperature. Its chemical composition was characterized by GC-MS analysis...
  12. Mettler S, Schwarz I, Colombani P. Additive postprandial blood glucose-attenuating and satiety-enhancing effect of cinnamon and acetic acid. Nutr Res. 2009;29:723-7 pubmed publisher
    ..Whether larger doses of cinnamon and acetic acid may result in a more substantial additive effect on blood glucose or satiety remains to be investigated...
  13. Gruenwald J, Freder J, Armbruester N. Cinnamon and health. Crit Rev Food Sci Nutr. 2010;50:822-34 pubmed publisher
    ..The use of cinnamon as an adjunct to the treatment of type 2 diabetes mellitus is the most promising area, but further research is needed before definitive recommendations can be made...
  14. Shen Y, Fukushima M, Ito Y, Muraki E, Hosono T, Seki T, et al. Verification of the antidiabetic effects of cinnamon (Cinnamomum zeylanicum) using insulin-uncontrolled type 1 diabetic rats and cultured adipocytes. Biosci Biotechnol Biochem. 2010;74:2418-25 pubmed
    It has long been believed that an intake of cinnamon (Cinnamomum zeylanicum) alleviates diabetic pathological conditions. However, it is still controversial whether the beneficial effect is insulin-dependent or insulin-mimetic...
  15. Jayaprakasha G, Rao L. Chemistry, biogenesis, and biological activities of Cinnamomum zeylanicum. Crit Rev Food Sci Nutr. 2011;51:547-62 pubmed publisher
    The genus Cinnamomum comprises of several hundreds of species, which are distributed in Asia and Australia. Cinnamomum zeylanicum, the source of cinnamon bark and leaf oils, is an indigenous tree of Sri Lanka, although most oil now comes ..
  16. Lee B, Kim Y, Cho D, Sohn N, Kang H. Immunomodulatory effect of water extract of cinnamon on anti-CD3-induced cytokine responses and p38, JNK, ERK1/2, and STAT4 activation. Immunopharmacol Immunotoxicol. 2011;33:714-22 pubmed publisher
    ..Cinnamon bark is a very popular herb used in traditional medicine to treat various disorders such as chronic gastric symptoms, arthritis, and the common cold...
  17. Ranasinghe P, Jayawardana R, Galappaththy P, Constantine G, de Vas Gunawardana N, Katulanda P. Efficacy and safety of 'true' cinnamon (Cinnamomum zeylanicum) as a pharmaceutical agent in diabetes: a systematic review and meta-analysis. Diabet Med. 2012;29:1480-92 pubmed publisher
    ..Studies have frequently looked at dietary components beneficial in treatment and prevention. We aim to systematically evaluate the literature on the safety and efficacy of Cinnamomum zeylanicum on diabetes.
  18. Nyadjeu P, Nguelefack Mbuyo E, Atsamo A, Nguelefack T, Dongmo A, Kamanyi A. Acute and chronic antihypertensive effects of Cinnamomum zeylanicum stem bark methanol extract in L-NAME-induced hypertensive rats. BMC Complement Altern Med. 2013;13:27 pubmed publisher
    Previous study showed that the aqueous extract of the stem bark of Cinnamomum zeylanicum possesses antihypertensive and vasodilatory properties...
  19. Khan A, Safdar M, Ali Khan M, Khattak K, Anderson R. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care. 2003;26:3215-8 pubmed
    ..The objective of this study was to determine whether cinnamon improves blood glucose, triglyceride, total cholesterol, HDL cholesterol, and LDL cholesterol levels in people with type 2 diabetes...
  20. Qin B, Nagasaki M, Ren M, Bajotto G, Oshida Y, Sato Y. Cinnamon extract prevents the insulin resistance induced by a high-fructose diet. Horm Metab Res. 2004;36:119-25 pubmed
    ..These results suggest that early CE administration to HFD-fed rats would prevent the development of insulin resistance at least in part by enhancing insulin signaling and possibly via the NO pathway in skeletal muscle...
  21. Senhaji O, Faid M, Kalalou I. Inactivation of Escherichia coli O157:H7 by essential oil from Cinnamomum zeylanicum. Braz J Infect Dis. 2007;11:234-6 pubmed
    ..coli. The minimal inhibitory concentration of the essential oil from cinnamon was around 625 ppm against E. coli O157:H7 and E. coli ATCC 25921, around 1250 ppm against E. coli ATCC25922 and around 2500 ppm against E. coli ATCC11105...
  22. Dugoua J, Seely D, Perri D, Cooley K, Forelli T, Mills E, et al. From type 2 diabetes to antioxidant activity: a systematic review of the safety and efficacy of common and cassia cinnamon bark. Can J Physiol Pharmacol. 2007;85:837-47 pubmed
    ..pylori infection. Common cinnamon showed weak to very weak evidence of efficacy in treating oral candidiasis in HIV patients and chronic salmonellosis...
  23. Cabello C, Bair W, Lamore S, Ley S, Bause A, Azimian S, et al. The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth. Free Radic Biol Med. 2009;46:220-31 pubmed publisher
    ..These findings support a previously unrecognized role of CA as a dietary Michael acceptor with potential anti-cancer activity...
  24. Kwon H, Jeon W, Hwang J, Lee C, So J, Park J, et al. Cinnamon extract suppresses tumor progression by modulating angiogenesis and the effector function of CD8+ T cells. Cancer Lett. 2009;278:174-182 pubmed publisher
    ..In conclusion, cinnamon extract has the potential to be an alternative medicine for tumor treatment. ..
  25. Javed I, Faisal I, RAHMAN Z, Khan M, Muhammad F, Aslam B, et al. Lipid lowering effect of Cinnamomum zeylanicum in hyperlipidaemic albino rabbits. Pak J Pharm Sci. 2012;25:141-7 pubmed
    The purpose of the present study was to investigate the lipid lowering effect of Cinnamomum zeylanicum (Cinnamon) in hyperlipidaemic albino rabbits...
  26. Vanschoonbeek K, Thomassen B, Senden J, Wodzig W, van Loon L. Cinnamon supplementation does not improve glycemic control in postmenopausal type 2 diabetes patients. J Nutr. 2006;136:977-80 pubmed
    ..More research on the proposed health benefits of cinnamon supplementation is warranted before health claims should be made...
  27. Brahmachari S, Jana A, Pahan K. Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses. J Immunol. 2009;183:5917-27 pubmed publisher
    ..These results highlight a novel anti-inflammatory role of NaB via modulation of the mevalonate pathway and p21(ras)...
  28. Lu J, Zhang K, Nam S, Anderson R, Jove R, Wen W. Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling. Carcinogenesis. 2010;31:481-8 pubmed publisher
    ..Our data revealed a novel activity in cinnamon and identified a natural VEGF inhibitor that could potentially be useful in cancer prevention and/or treatment...
  29. Kwon H, Hwang J, So J, Lee C, Sahoo A, Ryu J, et al. Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1. BMC Cancer. 2010;10:392 pubmed publisher
    ..In this study, we further identified that anti-tumor effect of cinnamon extracts is also link with enhanced pro-apoptotic activity by inhibiting the activities NFkappaB and AP1 in mouse melanoma model...
  30. Unlu M, Ergene E, Unlu G, Zeytinoglu H, Vural N. Composition, antimicrobial activity and in vitro cytotoxicity of essential oil from Cinnamomum zeylanicum Blume (Lauraceae). Food Chem Toxicol. 2010;48:3274-80 pubmed publisher
    The essential oil from the bark of Cinnamomum zeylanicum Blume was analyzed by GC-MS and bioassays were carried out. Nine constituents representing 99.24% of the oil were identified by GC-MS...
  31. Jayaprakasha G, Jagan Mohan Rao L, Sakariah K. Volatile constituents from Cinnamomum zeylanicum fruit stalks and their antioxidant activities. J Agric Food Chem. 2003;51:4344-8 pubmed
    b>Cinnamomum zeylanicum Blume is an important spice and aromatic crop having wide applications in flavoring, perfumery, beverages, and medicines. The steam-distilled volatile oil from cinnamon fruit stalks was analyzed with GC and GC-MS...
  32. Kamath J, Rana A, Chowdhury A. Pro-healing effect of Cinnamomum zeylanicum bark. Phytother Res. 2003;17:970-2 pubmed
    The ethanol extract of the bark of Cinnamomum zeylanicum was evaluated for wound healing activity in Wistar rats...
  33. Matan N, Rimkeeree H, Mawson A, Chompreeda P, Haruthaithanasan V, Parker M. Antimicrobial activity of cinnamon and clove oils under modified atmosphere conditions. Int J Food Microbiol. 2006;107:180-5 pubmed
    ..roqueforti, M. plumbeus, Eurotium sp., D. hansenii, and Z. rouxii, while inhibition of A. flavus required the addition of 4000 microL. Higher ratios of cinnamon oil/clove oil were more effective for inhibiting the growth of A. flavus...
  34. Jayaprakasha G, Ohnishi Kameyama M, Ono H, Yoshida M, Jaganmohan Rao L. Phenolic constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity. J Agric Food Chem. 2006;54:1672-9 pubmed
    ..All of the compounds showed antioxidant and radical scavenging activities. This is the first report of the isolation and identification of nonvolatile constituents and as well as antioxidant activities from cinnamon fruits...
  35. Peterson D, George R, Scaramozzino F, LaPointe N, Anderson R, Graves D, et al. Cinnamon extract inhibits tau aggregation associated with Alzheimer's disease in vitro. J Alzheimers Dis. 2009;17:585-97 pubmed publisher
    ..This work shows that compounds endogenous to cinnamon may be beneficial to AD themselves or may guide the discovery of other potential therapeutics if their mechanisms of action can be discerned...
  36. Khuwijitjaru P, Sayputikasikorn N, Samuhasaneetoo S, Penroj P, Siriwongwilaichat P, Adachi S. Subcritical water extraction of flavoring and phenolic compounds from cinnamon bark (Cinnamomum zeylanicum). J Oleo Sci. 2012;61:349-55 pubmed
    Cinnamon bark (Cinnamomum zeylanicum) powder was treated with subcritical water at 150 and 200°C in a semi-continuous system at a constant flow rate (3 mL/min) and pressure (6 MPa). Major flavoring compounds, i.e...
  37. Ranasinghe L, Jayawardena B, Abeywickrama K. Fungicidal activity of essential oils of Cinnamomum zeylanicum (L.) and Syzygium aromaticum (L.) Merr et L.M. Perry against crown rot and anthracnose pathogens isolated from banana. Lett Appl Microbiol. 2002;35:208-11 pubmed
    ..To develop a post-harvest treatment system against post-harvest fungal pathogens of banana using natural products...
  38. Kirkham S, Akilen R, Sharma S, Tsiami A. The potential of cinnamon to reduce blood glucose levels in patients with type 2 diabetes and insulin resistance. Diabetes Obes Metab. 2009;11:1100-13 pubmed publisher
  39. Magro A, Carolino M, Bastos M, Mexia A. Efficacy of plant extracts against stored-products fungi. Rev Iberoam Micol. 2006;23:176-8 pubmed
    ..garlic (Allium sativum L.), malva (Malva sylvestris L.) and peppermint (Mentha piperita L.). The more concentrated extracts of chamomile and malva inhibited totally the growth of the tested fungi with malva the most effective one...
  40. Hong J, Yang G, Kim Y, Eom S, Lew J, Kang H. Anti-inflammatory activity of cinnamon water extract in vivo and in vitro LPS-induced models. BMC Complement Altern Med. 2012;12:237 pubmed publisher
    ..Our results also indicate that the observed anti-inflammatory action of CWE may originate from the presence of polyphenols. ..
  41. Gu L, Kelm M, Hammerstone J, Zhang Z, Beecher G, Holden J, et al. Liquid chromatographic/electrospray ionization mass spectrometric studies of proanthocyanidins in foods. J Mass Spectrom. 2003;38:1272-80 pubmed
    ..Fragmentation patterns were proposed based on our data obtained by ESI-MS/MS and ESI time-of-flight MS. ..
  42. Corren J, Lemay M, Lin Y, Rozga L, Randolph R. Clinical and biochemical effects of a combination botanical product (ClearGuard) for allergy: a pilot randomized double-blind placebo-controlled trial. Nutr J. 2008;7:20 pubmed publisher
    Botanical products are frequently used for treatment of nasal allergy. Three of these substances, Cinnamomum zeylanicum, Malpighia glabra, and Bidens pilosa, have been shown to have a number of anti-allergic properties in-vitro...
  43. Govindarajan M. Larvicidal and repellent properties of some essential oils against Culex tritaeniorhynchus Giles and Anopheles subpictus Grassi (Diptera: Culicidae). Asian Pac J Trop Med. 2011;4:106-11 pubmed publisher
    ..and repellent properties of essential oils from various parts of four plant species Cymbopogan citrates, Cinnamomum zeylanicum, Rosmarinus officinalis and Zingiber officinale against Culex tritaeniorhynchus (Cx...
  44. Spindler S, Mote P, Flegal J, Teter B. Influence on longevity of blueberry, cinnamon, green and black tea, pomegranate, sesame, curcumin, morin, pycnogenol, quercetin, and taxifolin fed iso-calorically to long-lived, F1 hybrid mice. Rejuvenation Res. 2013;16:143-51 pubmed publisher
  45. Hartmann K, Hunzelmann N. Allergic contact dermatitis from cinnamon as an odour-neutralizing agent in shoe insoles. Contact Dermatitis. 2004;50:253-4 pubmed
  46. Tankam J, Sawada Y, Ito M. Regular ingestion of cinnamomi cortex pulveratus offers gastroprotective activity in mice. J Nat Med. 2013;67:289-95 pubmed publisher
    ..These findings indicate that regular ingestion of cinnamon powder offers gastroprotection presumably through a cytoprotective mechanism but the efficacy against NSAIDs-induced gastric ulcers may be limited. ..
  47. Toniolo R, Pizzariello A, Dossi N, Lorenzon S, Abollino O, Bontempelli G. Room temperature ionic liquids as useful overlayers for estimating food quality from their odor analysis by quartz crystal microbalance measurements. Anal Chem. 2013;85:7241-7 pubmed publisher
    ..PCA applied to responses recorded on different stocks of samples of both varieties showed that they could be fully discriminated. ..
  48. Mendi A, Yağci B, Kiziloğlu M, Saraç N, Yilmaz D, Uğur A, et al. Effects of Syzygium aromaticum, Cinnamomum zeylanicum, and Salvia triloba extracts on proliferation and differentiation of dental pulp stem cells. J Appl Oral Sci. 2017;25:515-522 pubmed publisher
    ..local irritative and cytotoxic effects are known for the chemical components of Syzygium aromaticum and Cinnamomum zeylanicum contained in dental materials...
  49. Wright J. Diagnosis and management of oral lichenoid reactions. J Calif Dent Assoc. 2007;35:412-6 pubmed
    ..This paper will discuss the more common lichenoid reactions seen in clinical practice and review the diagnosis and management of these conditions. ..
  50. Tremblay S, Avon S. Contact allergy to cinnamon: case report. J Can Dent Assoc. 2008;74:445-61 pubmed
    ..Treatment generally consists of eliminating the causal agent. To avoid unnecessary diagnostic procedures and treatments, it is important for clinicians to recognize this disorder to be able to diagnose it quickly and accurately. ..
  51. Leach M, Kumar S. Cinnamon for diabetes mellitus. Cochrane Database Syst Rev. 2012;:CD007170 pubmed publisher
    ..Further trials, which address the issues of allocation concealment and blinding, are now required. The inclusion of other important endpoints, such as health-related quality of life, diabetes complications and costs, is also needed. ..
  52. Whitfield P, Parry Strong A, Walsh E, Weatherall M, Krebs J. The effect of a cinnamon-, chromium- and magnesium-formulated honey on glycaemic control, weight loss and lipid parameters in type 2 diabetes: an open-label cross-over randomised controlled trial. Eur J Nutr. 2016;55:1123-31 pubmed publisher
    ..Use of the formulated honey was associated with a reduction in weight and improvements in lipid parameters, and should be investigated further. ..
  53. Watanabe J, Oki T, Takebayashi J, Yada H, Wagaki M, Takano Ishikawa Y, et al. Improvement and Interlaboratory Validation of the Lipophilic Oxygen Radical Absorbance Capacity: Determination of Antioxidant Capacities of Lipophilic Antioxidant Solutions and Food Extracts. Anal Sci. 2016;32:171-5 pubmed publisher
    ..0 to 16.7%, the reproducibility relative standard deviations (RSD(R)) ranged from 14.8 to 19.4%, and the HorRat values ranged from 1.35 to 1.78. ..
  54. Suganthi R, Rajamani S, Ravichandran M, Anuradha C. Effect of food seasoning spices mixture on biomarkers of oxidative stress in tissues of fructose-fed insulin-resistant rats. J Med Food. 2007;10:149-53 pubmed
    ..The positive effect of SM on the oxidant-antioxidant balance could be attributed to the active constituents of the different spices present in the mixture...
  55. Solomon T, Blannin A. Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans. Eur J Appl Physiol. 2009;105:969-76 pubmed publisher
    ..day 0; P < 0.05). These effects were lost following cessation of cinnamon feeding. Cinnamon may improve glycaemic control and insulin sensitivity, but the effects are quickly reversed. ..
  56. Markey O, McClean C, Medlow P, Davison G, Trinick T, Duly E, et al. Effect of cinnamon on gastric emptying, arterial stiffness, postprandial lipemia, glycemia, and appetite responses to high-fat breakfast. Cardiovasc Diabetol. 2011;10:78 pubmed publisher
    ..We aimed to determine the effect of 3 g cinnamon (Cinnamomum zeylanicum) on GE, postprandial lipemic and glycemic responses, oxidative stress, arterial stiffness, as well as ..
  57. Krieger S, Hayen H, Schmitz O. Quantification of coumarin in cinnamon and woodruff beverages using DIP-APCI-MS and LC-MS. Anal Bioanal Chem. 2013;405:8337-45 pubmed publisher
    ..The temperature-programmed vaporization in DIP-APCI-MS combined with the use of stable isotope-labeled coumarin as internal standard helped in recognizing this interference. ..
  58. Bhinge S, Bhutkar M, Randive D, Wadkar G, Todkar S, Kakade P, et al. Formulation development and evaluation of antimicrobial polyherbal gel. Ann Pharm Fr. 2017;75:349-358 pubmed publisher
    ..which comprised of ethanolic extract of Azadirachta indica, Curcuma longa, Allium sativum, Ocimum sactum, Cinnamomum zeylanicum nees and Tamarindus indica in a concentration of 0.1 and 0.5%, respectively in a base...
  59. Soliman K, Badeaa R. Effect of oil extracted from some medicinal plants on different mycotoxigenic fungi. Food Chem Toxicol. 2002;40:1669-75 pubmed
    ..The extent of inhibition of fungal growth and mycotoxin production was dependent on the concentration of essential oils used...
  60. Qin B, Polansky M, Anderson R. Cinnamon extract regulates plasma levels of adipose-derived factors and expression of multiple genes related to carbohydrate metabolism and lipogenesis in adipose tissue of fructose-fed rats. Horm Metab Res. 2010;42:187-93 pubmed publisher
    ..These results suggest that CE effectively ameliorates circulating levels of adipokines partially mediated via regulation of the expression of multiple genes involved in insulin sensitivity and lipogenesis in the EAT. ..
  61. Mateos Martín M, Fuguet E, Quero C, Pérez Jiménez J, Torres J. New identification of proanthocyanidins in cinnamon (Cinnamomum zeylanicum L.) using MALDI-TOF/TOF mass spectrometry. Anal Bioanal Chem. 2012;402:1327-36 pubmed publisher
    The inner bark of Ceylon cinnamon (Cinnamomum zeylanicum L.) is commonly used as a spice and has also been widely employed in the treatment and prevention of disease...
  62. Gopu C, Aher S, Mehta H, Paradkar A, Mahadik K. Simultaneous determination of cinnamaldehyde, eugenol and piperine by HPTLC densitometric method. Phytochem Anal. 2008;19:116-21 pubmed
    ..The linearity was found to be in the ranges 52.54-735.56, 533.2-8531.2 and 50-300 ng/spot, respectively, with correlation coefficients of 0.9985 +/- 0.04, 0.9982 +/- 0.06 and 0.9937 +/- 0.11 for cinnamaldehyde, eugenol and piperine. ..
  63. Bhattacharjee S, Rana T, Sengupta A. Inhibition of lipid peroxidation and enhancement of GST activity by cardamom and cinnamon during chemically induced colon carcinogenesis in Swiss albino mice. Asian Pac J Cancer Prev. 2007;8:578-82 pubmed
  64. Hagenlocher Y, Bergheim I, Zacheja S, Schaffer M, Bischoff S, Lorentz A. Cinnamon extract inhibits degranulation and de novo synthesis of inflammatory mediators in mast cells. Allergy. 2013;68:490-7 pubmed publisher
    ..CE decreases expression of mast cell-specific mediators in vitro and in vivo and thus is a new plant-originated candidate for anti-allergic therapy. ..
  65. Endo H, Rees T. Clinical features of cinnamon-induced contact stomatitis. Compend Contin Educ Dent. 2006;27:403-9; quiz 410, 421 pubmed
    ..It is important to identify the causative agents of such a disorder by understanding characteristic signs and symptoms and conducting an appropriate inquiry. ..
  66. Blahova J, Svobodova Z. Assessment of coumarin levels in ground cinnamon available in the Czech retail market. ScientificWorldJournal. 2012;2012:263851 pubmed publisher
    ..The high coumarin content confirmed that these cinnamon samples obtained from cassia cinnamon were in contrast to the sample from Sri Lanka, which was coumarin-free. ..
  67. Tanaka T, Matsuo Y, Yamada Y, Kouno I. Structure of polymeric polyphenols of cinnamon bark deduced from condensation products of cinnamaldehyde with catechin and procyanidins. J Agric Food Chem. 2008;56:5864-70 pubmed publisher
  68. Abdel Halim A. Efficacy of Cinnamomum zeylanicum on third stage larvae and adult fecundity of Musca domestica and Anopheles pharoensis. J Egypt Soc Parasitol. 2008;38:475-82 pubmed
    The insecticidal activity of Cinnamomum zeylanicum against the larval maturation and adult emergency of Anopheles pharoensis and Musca domestica 3rd stage was evaluated under controlled laboratory conditions. A...
  69. Meades G, Henken R, Waldrop G, Rahman M, Gilman S, Kamatou G, et al. Constituents of cinnamon inhibit bacterial acetyl CoA carboxylase. Planta Med. 2010;76:1570-5 pubmed publisher
    Cinnamon bark ( CINNAMOMUM ZEYLANICUM) is used extensively as an antimicrobial material and currently is being increasingly used in Europe by people with type II diabetes to control their glucose levels...
  70. Davis P, Yokoyama W. Cinnamon intake lowers fasting blood glucose: meta-analysis. J Med Food. 2011;14:884-9 pubmed publisher
    ..49±0.2 mmol/L; n=8, P=.025) and intake of cinnamon extract only also lowered FBG (-0.48 mmol/L±0.17; n=5, P=.008). Thus cinnamon extract and/or cinnamon improves FBG in people with type 2 diabetes or prediabetes. ..
  71. Becerril R, Nerin C, Gómez Lus R. Evaluation of bacterial resistance to essential oils and antibiotics after exposure to oregano and cinnamon essential oils. Foodborne Pathog Dis. 2012;9:699-705 pubmed publisher
    ..However, the changes in antibiotic and oregano resistance were not related. ..
  72. Qin B, Dawson H, Schoene N, Polansky M, Anderson R. Cinnamon polyphenols regulate multiple metabolic pathways involved in insulin signaling and intestinal lipoprotein metabolism of small intestinal enterocytes. Nutrition. 2012;28:1172-9 pubmed publisher
    ..The aim of the study was to investigate the effects of a CE on the primary enterocytes of chow-fed rats...
  73. Wang L, Yang X, Chen H, Gong T, Li W, Yang G, et al. Design of triple-shape memory polyurethane with photo-cross-linking of cinnamon groups. ACS Appl Mater Interfaces. 2013;5:10520-8 pubmed publisher
    ..Alamar blue assay showed that the material has good non-cytotoxicity and can be potentially used in biomaterial devices. ..
  74. Hagenlocher Y, Hösel A, Bischoff S, Lorentz A. Cinnamon extract reduces symptoms, inflammatory mediators and mast cell markers in murine IL-10(-/-) colitis. J Nutr Biochem. 2016;30:85-92 pubmed publisher
    ..CE has no influence on tight junction proteins, but seems acting via reducing pro-inflammatory mediators and recruitment of neutrophil granulocytes probably by inhibiting NF-κB signaling. ..
  75. Yuste J, Fung D. Inactivation of Listeria monocytogenes Scott A 49594 in apple juice supplemented with cinnamon. J Food Prot. 2002;65:1663-6 pubmed
    ..0 samples with 0.1% of cinnamon. The TAL method was as effective as TSA in recovering injured cells of L. monocytogenes. Cinnamon considerably inactivates L. monocytogenes in apple juice and thus enhances the safety of this product. ..
  76. Chase C, McQueen C. Cinnamon in diabetes mellitus. Am J Health Syst Pharm. 2007;64:1033-5 pubmed
  77. Kumar A, Singh B, Malik A, Tiwary D. Determination of some aldehydes by using solid-phase microextraction and high-performance liquid chromatography with UV detection. J AOAC Int. 2007;90:1689-94 pubmed
    ..The proposed method was validated by determining benzaldehyde in bitter almonds and cinnamaldehyde in cinnamon bark. The recoveries of the 5 analytes were determined by analysis of spiked drinking water. ..
  78. Jin S, Cho K. Water extracts of cinnamon and clove exhibits potent inhibition of protein glycation and anti-atherosclerotic activity in vitro and in vivo hypolipidemic activity in zebrafish. Food Chem Toxicol. 2011;49:1521-9 pubmed publisher
    ..These results suggest the potential to develop a new functional dietary agent to treat chronic metabolic diseases, such as hyperlipidemia and diabetes. ..
  79. Mattes R. Spices and energy balance. Physiol Behav. 2012;107:584-90 pubmed publisher
    ..Flavor active compounds hold some promise for being more a part of the solution than the problem of disordered eating and unhealthy weight. ..
  80. Zamani Zadeh M, Soleimanian Zad S, Sheikh Zeinoddin M. Biocontrol of gray mold disease on strawberry fruit by integration of Lactobacillus plantarum A7 with ajwain and cinnamon essential oils. J Food Sci. 2013;78:M1582-M1588 pubmed publisher
    ..To the best of our knowledge, this is the first report on the effects of combination of a Lactobacillus as an antagonist bacterium with essential oils to increase the shelf life of strawberry. ..
  81. Alotaibi M. The effect of cinnamon extract on isolated rat uterine strips. Reprod Biol. 2016;16:27-33 pubmed publisher
    ..As a result, cinnamon may be used to alleviate menstrual pain associated with dysmenorrhoea or prevent unwanted uterine activity in early pregnancy. ..
  82. Oussalah M, Caillet S, Salmieri S, Saucier L, Lacroix M. Antimicrobial effects of alginate-based films containing essential oils on Listeria monocytogenes and Salmonella typhimurium present in bologna and ham. J Food Prot. 2007;70:901-8 pubmed
    ..C-based film pretreated by immersion in a 20% CaCl2 solution was most efficient against both pathogens, and migration of active compounds was higher in C-based films than in O- and S-based films...
  83. Cheng D, Kuhn P, Poulev A, Rojo L, Lila M, Raskin I. In vivo and in vitro antidiabetic effects of aqueous cinnamon extract and cinnamon polyphenol-enhanced food matrix. Food Chem. 2012;135:2994-3002 pubmed publisher
    ..The hypoglycemic and insulin-like effects of CE and CDSF may help to ameliorate type 2 diabetes conditions...
  84. Endres C, Lohmann K. Perception of dimethyl sulfide (DMS) by loggerhead sea turtles: a possible mechanism for locating high-productivity oceanic regions for foraging. J Exp Biol. 2012;215:3535-8 pubmed
    ..The results demonstrate for the first time that sea turtles can detect DMS, an ability that might enable the identification of favorable foraging areas...
  85. Sedghizadeh P, Allen C. White plaque of the lateral tongue. J Contemp Dent Pract. 2002;3:46-50 pubmed
    ..The problem seemed to be limited to her left lateral tongue and had been noticed for at least six months by the patient. She also indicated the condition varied in severity...
  86. Siegel M. Perioral dermatitis. J Am Dent Assoc. 2006;137:1121-2 pubmed
  87. Zhang B, Liu Q. [Clinic utilization of Guizhi decoction in modern times]. Zhongguo Zhong Yao Za Zhi. 2007;32:757-60 pubmed
    ..and covers various clinic illness such as internal medicine, surgery, gynaecology and obstetrics, pediatrics, ophthalmology and otorhinolaryngology, stomatology, etc...
  88. Jitomir J, Willoughby D. Cassia cinnamon for the attenuation of glucose intolerance and insulin resistance resulting from sleep loss. J Med Food. 2009;12:467-72 pubmed publisher
    ..Because peripheral insulin resistance is primarily a consequence of reduced muscle insulin sensitivity, C. cassia and C. cassia extracts may attenuate insulin resistance and glucose intolerance observed following sleep loss...
  89. Fitzpatrick L, Healy C, McCartan B, Flint S, McCreary C, Rogers S. Patch testing for food-associated allergies in orofacial granulomatosis. J Oral Pathol Med. 2011;40:10-3 pubmed publisher
    ..Elimination diets have also been shown to be effective in some patients...
  90. Amalaradjou M, Venkitanarayanan K. Proteomic analysis of the mode of antibacterial action of trans-cinnamaldehyde against Cronobacter sakazakii 415. Foodborne Pathog Dis. 2011;8:1095-102 pubmed publisher
    ..sakazakii against oxidative stress, thereby reducing its virulence. The results of this study suggest that TC could be potentially used for controlling C. sakazakii...
  91. Shaltiel Karyo R, Davidi D, Frenkel Pinter M, Ovadia M, Segal D, Gazit E. Differential inhibition of ?-synuclein oligomeric and fibrillar assembly in parkinson's disease model by cinnamon extract. Biochim Biophys Acta. 2012;1820:1628-35 pubmed publisher
    ..Yet, it is still debatable whether oligomers are formed as part of a multistep process towards amyloid fibril formation or alternatively as "off-pathway" aggregates...
  92. Jain S, Sangma T, Shukla S, Mediratta P. Effect of Cinnamomum zeylanicum extract on scopolamine-induced cognitive impairment and oxidative stress in rats. Nutr Neurosci. 2015;18:210-6 pubmed publisher
    b>Cinnamomum zeylanicum (CZ) is commonly known as cinnamon in traditional system of medicine having antibacterial, antioxidant, antidiabetic, hypolipidemic, and other activities...