pausinystalia

Summary

Summary: A plant genus of the family RUBIACEAE. Members produce YOHIMBINE.

Top Publications

  1. Ajayi A, Newaz M, Hercule H, Saleh M, Bode C, Oyekan A. Endothelin-like action of Pausinystalia yohimbe aqueous extract on vascular and renal regional hemodynamics in Sprague Dawley rats. Methods Find Exp Clin Pharmacol. 2003;25:817-22 pubmed
    The bark of the African tree Pausinystalia yohimbe has been used as a food additive with aphrodisiac and penile erection enhancing properties. The effect of an aqueous extract of P...
  2. Chen Q, Li P, Zhang Z, Li K, Liu J, Li Q. Analysis of yohimbine alkaloid from Pausinystalia yohimbe by non-aqueous capillary electrophoresis and gas chromatography-mass spectrometry. J Sep Sci. 2008;31:2211-8 pubmed publisher
    In the present work, the qualitative and quantitative analysis of Pausinystalia yohimbe-type alkaloids in the barks of Rubiaceae species is presented using different analytical approaches. Extracts of P...
  3. van Wyk B. A review of commercially important African medicinal plants. J Ethnopharmacol. 2015;176:118-34 pubmed publisher
    ..g. caffeine from Coffea arabica and yohimbine from Pausinystalia johimbe)...
  4. Custers D, Van Praag N, Courselle P, Apers S, Deconinck E. Chromatographic fingerprinting as a strategy to identify regulated plants in illegal herbal supplements. Talanta. 2017;164:490-502 pubmed publisher
    ..b>Pausinystalia yohimbe and Tribulus terrestris...
  5. Zanolari B, Ndjoko K, Ioset J, Marston A, Hostettmann K. Qualitative and quantitative determination of yohimbine in authentic yohimbe bark and in commercial aphrodisiacs by HPLC-UV-API/ MS methods. Phytochem Anal. 2003;14:193-201 pubmed
    ..Twenty commercial aphrodisiac preparations were analysed and the amount of yohimbine measured and expressed as the maximal dose per day suggested on product labels ranged from 1.32 to 23.16 mg...
  6. Smith D, Dyve S, Minuzzi L, Jakobsen S, Munk O, Marthi K, et al. Inhibition of [11C]mirtazapine binding by alpha2-adrenoceptor antagonists studied by positron emission tomography in living porcine brain. Synapse. 2006;59:463-71 pubmed
    ..Thus, PET studies confirm that [(11)C]mirtazapine affects alpha(2)-adrenoceptor binding sites in living brain...
  7. Al Majed A, Al Yahya A, Al Bekairi A, Al Shabanah O, Qureshi S. Reproductive, cytological and biochemical toxicity of Yohimbe in male Swiss albino mice. Asian J Androl. 2006;8:469-76 pubmed
    ..To study the effect of Corynanthe Yohimbe (Yohimbe) on germ cells in Swiss albino mice...
  8. Myers A, Barrueto F. Refractory priapism associated with ingestion of yohimbe extract. J Med Toxicol. 2009;5:223-5 pubmed
    Extracts of the bark of the central African tree Pausinystalia yohimbe contain yohimbine, an indole alkaloid, which is used to treat erectile dysfunction...
  9. Sun J, Chen P. Chromatographic fingerprint analysis of yohimbe bark and related dietary supplements using UHPLC/UV/MS. J Pharm Biomed Anal. 2012;61:142-9 pubmed publisher
    ..Wide variability was observed in fingerprints and yohimbine content among yohimbe dietary supplement samples. For most of the dietary supplements, the yohimbine content was not consistent with the label claims...

More Information

Publications14

  1. Cohen P, Wang Y, Maller G, deSouza R, Khan I. Pharmaceutical quantities of yohimbine found in dietary supplements in the USA. Drug Test Anal. 2016;8:357-69 pubmed publisher
    ..Extracts of the evergreen tree yohimbe, Pausinystalia johimbe, though banned in many countries, are sold in hundreds of dietary supplements in the USA...
  2. Bovee T, Mol H, Bienenmann Ploum M, Heskamp H, van Bruchem G, van Ginkel L, et al. Dietary supplement for energy and reduced appetite containing the ?-agonist isopropyloctopamine leads to heart problems and hospitalisations. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2016;33:749-59 pubmed publisher
    ..The case shows the strength of combining bioassays with chemical analytical techniques for identification of illegal pharmacologically active substances in food supplements. ..
  3. Fiol N, Escudero C, Villaescusa I. Chromium sorption and Cr(VI) reduction to Cr(III) by grape stalks and yohimbe bark. Bioresour Technol. 2008;99:5030-6 pubmed
    ..Results put into evidence that both sorbents are able to reduce Cr(VI) to its trivalent form...
  4. Raman V, Avula B, Galal A, Wang Y, Khan I. Microscopic and UPLC-UV-MS analyses of authentic and commercial yohimbe (Pausinystalia johimbe) bark samples. J Nat Med. 2013;67:42-50 pubmed publisher
    Yohimbine is the major alkaloid found in the stem bark of yohimbe, Pausinystalia johimbe (Rubiaceae), an evergreen tree native to Africa...
  5. Sun J, Baker A, Chen P. Profiling the indole alkaloids in yohimbe bark with ultra-performance liquid chromatography coupled with ion mobility quadrupole time-of-flight mass spectrometry. Rapid Commun Mass Spectrom. 2011;25:2591-602 pubmed publisher