rubiaceae

Summary

Summary: The Madder plant family of the order Gentianales (formerly Rubiales), subclass Asteridae, class Magnoliopsida includes important medicinal plants that provide QUININE; IPECAC; and COFFEE. They have opposite leaves and interpetiolar stipules.

Top Publications

  1. Mongrand S, Badoc A, Patouille B, Lacomblez C, Chavent M, Bessoule J. Chemotaxonomy of the Rubiaceae family based on leaf fatty acid composition. Phytochemistry. 2005;66:549-59 pubmed
    With 10,700 species distributed in 637 genera, the Rubiaceae family is one of the largest of the angiosperms...
  2. Razafimandimbison S, Rydin C, Bremer B. Evolution and trends in the Psychotrieae alliance (Rubiaceae)--a rarely reported evolutionary change of many-seeded carpels from one-seeded carpels. Mol Phylogenet Evol. 2008;48:207-23 pubmed publisher
    Bayesian and parsimony analyses of five plastid gene and nrITS regions from 58 Rubioideae (Rubiaceae) taxa further support the sister-group relationship between the African monotypic genus Schizocolea and the Psychotrieae alliance sensu ..
  3. Mesia K, Cimanga R, Dhooghe L, Cos P, Apers S, Totté J, et al. Antimalarial activity and toxicity evaluation of a quantified Nauclea pobeguinii extract. J Ethnopharmacol. 2010;131:10-6 pubmed publisher
    ..Ex. Pell.) Petit (Rubiaceae), a plant used in traditional medicine in DR Congo against malaria. The aqueous and 80% EtOH extract from N...
  4. Sibandze G, van Zyl R, van Vuuren S. The anti-diarrhoeal properties of Breonadia salicina, Syzygium cordatum and Ozoroa sphaerocarpa when used in combination in Swazi traditional medicine. J Ethnopharmacol. 2010;132:506-11 pubmed publisher
    ..Fern & A. Fern (Anacardiaceae), Breonadia salicina (Vahl) Hepper & J.I.R. Wood (Rubiaceae) and Syzygium cordatum Hochst ex C Krauss (Myrtaceae) against a diarrhoea-causing pathogen, Escherichia coli; as ..
  5. Mesia K, Cimanga K, Tona L, Mampunza M, Ntamabyaliro N, Muanda T, et al. Assessment of the short-term safety and tolerability of a quantified 80 % ethanol extract from the stem bark of Nauclea pobeguinii (PR 259 CT1) in healthy volunteers: a clinical phase I study. Planta Med. 2011;77:111-6 pubmed publisher
    ..Other minor side effects were insomnia, somnolence and asthenia (7 %). Thus, PR 259 CT1 presented a significant safety and tolerability in healthy volunteers to allow its further development by starting a phase II clinical trial. ..
  6. Guerrero Analco J, Medina Campos O, Brindis F, Bye R, Pedraza Chaverri J, Navarrete A, et al. Antidiabetic properties of selected Mexican copalchis of the Rubiaceae family. Phytochemistry. 2007;68:2087-95 pubmed
    ..latiflora regulated hepatic glycogen and plasma insulin levels (p<0.05). These data suggest that its antihyperglycemic effect is due in part to stimulation of insulin secretion and regulation of hepatic glycogen metabolism...
  7. Lersten N, Horner H. Unique calcium oxalate "duplex" and "concretion" idioblasts in leaves of tribe Naucleeae (Rubiaceae). Am J Bot. 2011;98:1-11 pubmed publisher
    ..One, unillustrated report mentions druses and crystal sand from one species of tribe Naucleeae (Rubiaceae) and "occasional occurrences" in additional unnamed taxa...
  8. Moraes T, Barros C, Silva Neto S, Gomes V, DA Cunha M. Leaf blade anatomy and ultrastructure of six Simira species (Rubiaceae) from the Atlantic rain forest, Brazil. Biocell. 2009;33:155-65 pubmed
    ..The leaf blades show typical characteristics of the Rubiaceae family as dorsiventral mesophyll and paracytic stomata...
  9. Karou S, Tchacondo T, Ilboudo D, Simpore J. Sub-Saharan Rubiaceae: a review of their traditional uses, phytochemistry and biological activities. Pak J Biol Sci. 2011;14:149-69 pubmed
    b>Rubiaceae family is a large family of 630 genera and about 13000 species found worldwide, especially in tropical and warm regions...

More Information

Publications98

  1. Razafimandimbison S, Kellogg E, Bremer B. Recent origin and phylogenetic utility of divergent ITS putative pseudogenes: a case study from Naucleeae (Rubiaceae). Syst Biol. 2004;53:177-92 pubmed
    ..of ITS polymorphism (up to 30%, 40%, and 14%, respectively) in three tropical tree species of the coffee family (Rubiaceae), Adinauclea fagifolia, Haldina cordifolia, and Mitragyna rubrostipulata...
  2. Gutierrez Rodriguez C, Ornelas J, Rodríguez Gómez F. Chloroplast DNA phylogeography of a distylous shrub (Palicourea padifolia, Rubiaceae) reveals past fragmentation and demographic expansion in Mexican cloud forests. Mol Phylogenet Evol. 2011;61:603-15 pubmed publisher
  3. Osman C, Ismail N, Ahmad R, Ahmat N, Awang K, Jaafar F. Anthraquinones with antiplasmodial activity from the roots of Rennellia elliptica Korth. (Rubiaceae). Molecules. 2010;15:7218-26 pubmed publisher
    ..The new anthraquinone 1, 2-formyl-3-hydroxy-9,10-anthraquinone (4) and 3-hydroxy-2-methyl-9,10-anthraquinone (7) possess strong antiplasmodial activity, with IC?? values of 1.10, 0.63 and 0.34 µM, respectively...
  4. SanMartin Gajardo I, Morellato L. Inter and intraspecific variation on reproductive phenology of the Brazilian Atlantic forest Rubiaceae: ecology and phylogenetic constraints. Rev Biol Trop. 2003;51:691-8 pubmed
    The reproductive phenology of seven species of Rubiaceae from the Brazilian Atlantic rain forest was compared to evaluate the occurrence of phylogenetic constraints on flowering and fruiting phenologies...
  5. Lawrence J, Foggin C, Prozesky L. Gousiekte in African buffalo (Syncerus caffer). J S Afr Vet Assoc. 2010;81:170-1 pubmed
    ..The buffalo had had access to Pavetta schumanniana, a plant that is known to cause gousiekte. Death was attributed to cardiac failure as a result of previous consumption of the plant, exacerbated by the stress of translocation...
  6. Ma Y, Zhou L, Yan H, Liu M. Effects of extracts from Paederia scandens (LOUR.) MERRILL (Rubiaceae) on MSU crystal-induced rats gouty arthritis. Am J Chin Med. 2009;37:669-83 pubmed
    The effects of extract of Paederia scandens (LOUR.) MERRILL (Rubiaceae) (EPS), a Chinese traditional herbal medicine, on inflammatory and immune responses and their mechanisms in MSU crystals-induced (GA) rats were studied...
  7. Razafimandimbison S, Ekman S, McDowell T, Bremer B. Evolution of growth habit, inflorescence architecture, flower size, and fruit type in Rubiaceae: its ecological and evolutionary implications. PLoS ONE. 2012;7:e40851 pubmed publisher
    ..Morindeae (Rubiaceae) display considerable diversity in growth form, inflorescence architecture, flower size, and fruit type...
  8. Wabo Pone J, Bilong Bilong C, Mpoame M. In vitro nematicidal activity of extracts of Canthium mannii (Rubiaceae), on different life-cycle stages of Heligmosomoides polygyrus (Nematoda, Heligmosomatidae). J Helminthol. 2010;84:156-65 pubmed publisher
    ..The potential nematicidal activities of four extracts from the bark of Canthium mannii (Rubiaceae) stem were investigated in vitro...
  9. Nakamura K, Chung S, Kokubugata G, Denda T, Yokota M. Phylogenetic systematics of the monotypic genus Hayataella (Rubiaceae) endemic to Taiwan. J Plant Res. 2006;119:657-61 pubmed
    Hayataella (Rubiaceae) is a monotypic genus endemic to Taiwan that comprises H. michelloides...
  10. Afroz S, Alamgir M, Khan M, Jabbar S, Nahar N, Choudhuri M. Antidiarrhoeal activity of the ethanol extract of Paederia foetida Linn. (Rubiaceae). J Ethnopharmacol. 2006;105:125-30 pubmed
    ..The results suggest that Paederia foetida showed antidiarrhoeal activity by inhibiting intestinal motility and justify its use in traditional medicine...
  11. Queiroz C, Batista F, de Oliveira L. Evolution of the 5.8S nrDNA gene and internal transcribed spacers in Carapichea ipecacuanha (Rubiaceae) within a phylogeographic context. Mol Phylogenet Evol. 2011;59:293-302 pubmed publisher
    ..We argue that it is important to consider past evolutionary history when making inferences about the efficiency with which concerted evolution homogenizes tandem nrDNA repeats a single sequence...
  12. Kårehed J, Groeninckx I, Dessein S, Motley T, Bremer B. The phylogenetic utility of chloroplast and nuclear DNA markers and the phylogeny of the Rubiaceae tribe Spermacoceae. Mol Phylogenet Evol. 2008;49:843-66 pubmed publisher
    ..trnL-F) and nuclear (ETS, ITS) DNA regions was investigated for the tribe Spermacoceae of the coffee family (Rubiaceae)...
  13. Mavi A, Terzi Z, Ozgen U, Yildirim A, Coskun M. Antioxidant properties of some medicinal plants: Prangos ferulacea (Apiaceae), Sedum sempervivoides (Crassulaceae), Malva neglecta (Malvaceae), Cruciata taurica (Rubiaceae), Rosa pimpinellifolia (Rosaceae), Galium verum subsp. verum (Rubiaceae), Urti. Biol Pharm Bull. 2004;27:702-5 pubmed
    ..However, the highest DPPH radical scavenging activity, reducing power and the amount of phenolic compounds were shown by R. pimpinellifolia. The lowest antioxidant properties were shown by aqueous extract of M. neglecta...
  14. Zheng B, Zeng Y, Dai H, Zuo W, Guo Z, Yang T, et al. Two new meroterpenes from endophytic fungus A1 of Scyphiphora hydrophyllacea. J Asian Nat Prod Res. 2012;14:776-9 pubmed publisher
    ..F. Their structures were established based on spectroscopic methods including 1D and 2D NMR (HMQC, (1)H-(1)H COSY, HMBC, and ROESY)...
  15. Kolár F, Lučanová M, Vít P, Urfus T, Chrtek J, Fér T, et al. Diversity and endemism in deglaciated areas: ploidy, relative genome size and niche differentiation in the Galium pusillum complex (Rubiaceae) in Northern and Central Europe. Ann Bot. 2013;111:1095-108 pubmed publisher
    ..The Galium pusillum aggregate (Rubiaceae) is a challenging species complex that exhibits a marked differentiation in boreal parts of Northern Europe...
  16. Hernandez A, Ornelas J. Development of distylous flowers and investment of biomass in male and female function in Palicourea padifolia (Rubiaceae). Plant Biol (Stuttg). 2007;9:694-704 pubmed
    ..Variations observed in sexual investment between floral morphs suggest differences in sex expression during flower development...
  17. Klein D, Freitas L, Da Cunha M. Self-incompatibility in a distylous species of Rubiaceae: is there a single incompatibility response of the morphs?. Sex Plant Reprod. 2009;22:121-31 pubmed publisher
    ..These results support the hypothesis that L- and S-morph flowers have different incompatibility mechanisms during HetSI...
  18. da Conceição A, Rossi M, de Oliveira F, Takser L, Lafond J. Genipa americana (Rubiaceae) fruit extract affects mitogen-activated protein kinase cell pathways in human trophoblast-derived BeWo cells: implications for placental development. J Med Food. 2011;14:483-94 pubmed publisher
    Genipa americana L. (Rubiaceae) is a fruit tree and a traditional medicine used to treat anemia, icterus, asthma, and liver and spleen problems. The aim of the present study was to verify the effect of G...
  19. Zhu W, Pang M, Dong L, Huang X, Wang S, Zhou L. Anti-inflammatory and immunomodulatory effects of iridoid glycosides from Paederia scandens (LOUR.) MERRILL (Rubiaceae) on uric acid nephropathy rats. Life Sci. 2012;91:369-376 pubmed publisher
    ..scandens (LOUR.) MERRILL (Rubiaceae)...
  20. Dabiri M, Salimi S, Ghassempour A, Rassouli A, Talebi M. Optimization of microwave-assisted extraction for alizarin and purpurin in Rubiaceae plants and its comparison with conventional extraction methods. J Sep Sci. 2005;28:387-96 pubmed
    ..was developed and optimized for two common color pigments, alizarin and purpurin, in various samples of Rubiaceae plants...
  21. Lemaire B, Robbrecht E, Van Wyk B, Van Oevelen S, Verstraete B, Prinsen E, et al. Identification, origin, and evolution of leaf nodulating symbionts of Sericanthe (Rubiaceae). J Microbiol. 2011;49:935-41 pubmed publisher
    ..This phenomenon has been reported in three genera of Rubiaceae (Pavetta, Psychotria, and Sericanthe), but the bacterial partner has only been identified in Psychotria and ..
  22. Taïwe G, Bum E, Talla E, Dimo T, Weiss N, Sidiki N, et al. Antipyretic and antinociceptive effects of Nauclea latifolia root decoction and possible mechanisms of action. Pharm Biol. 2011;49:15-25 pubmed publisher
    Nauclea latifolia Smith (Rubiaceae) is a small tree found in tropical areas in Africa. It is used in traditional medicine to treat malaria, epilepsy, anxiety, pain, fever, etc.
  23. Abbah J, Amos S, Chindo B, Ngazal I, Vongtau H, Adzu B, et al. Pharmacological evidence favouring the use of Nauclea latifolia in malaria ethnopharmacy: effects against nociception, inflammation, and pyrexia in rats and mice. J Ethnopharmacol. 2010;127:85-90 pubmed publisher
  24. Cimanga R, Mukenyi P, Kambu O, Tona G, Apers S, Totte J, et al. The spasmolytic activity of extracts and some isolated compounds from the leaves of Morinda morindoides (Baker) Milne-Redh. (Rubiaceae). J Ethnopharmacol. 2010;127:215-20 pubmed publisher
  25. Liu M, Zhou L, Chen Z, Hu C. Analgesic effect of iridoid glycosides from Paederia scandens (LOUR.) MERRILL (Rubiaceae) on spared nerve injury rat model of neuropathic pain. Pharmacol Biochem Behav. 2012;102:465-70 pubmed publisher
    ..scandens (LOUR.) MERRILL (Rubiaceae)...
  26. Prachayasittikul S, Buraparuangsang P, Worachartcheewan A, Isarankura Na Ayudhya C, Ruchirawat S, Prachayasittikul V. Antimicrobial and antioxidative activities of bioactive constituents from Hydnophytum formicarum Jack. Molecules. 2008;13:904-21 pubmed
    Hydnophytum formicarum Jack. (Rubiaceae) is a medicinal plant whose tubers possesses cardiovascular, anti-inflammatory and antiparasitic effects and have been used for the treatment of hepatitis, rheumatism and diarrhea...
  27. Wabo Pone J, Mbida M, Bilong Bilong C. In vivo evaluation of potential nematicidal properties of ethanol extract of Canthium mannii (Rubiaceae) on Heligmosomoides polygyrus parasite of rodents. Vet Parasitol. 2009;166:103-7 pubmed publisher
    The nematicidal activity of ethanol extract (ETE) of Canthium mannii (Rubiaceae) was assessed in vivo compared to that of Mebendazole on the adult of Heligmosomoides polygyrus parasite of rodents...
  28. Lemaire B, Van Oevelen S, De Block P, Verstraete B, Smets E, Prinsen E, et al. Identification of the bacterial endosymbionts in leaf nodules of Pavetta (Rubiaceae). Int J Syst Evol Microbiol. 2012;62:202-9 pubmed publisher
    Three genera in the Rubiaceae (Pavetta, Psychotria and Sericanthe) harbour bacterial endosymbionts within leaf nodules or galls. The present paper identifies the bacterial endophytes in three leaf-nodulating Pavetta species...
  29. González Astorga J, Castillo Campos G. Genetic variability of the narrow endemic tree Antirhea aromatica Castillo-Campos Lorence, (Rubiaceae, Guettardeae) in a tropical forest of Mexico. Ann Bot. 2004;93:521-8 pubmed
    ..variability were examined in the only three extant populations of the narrow-endemic tree Antirhea aromatica (Rubiaceae, Guettardeae), an endangered species of the tropical forest of eastern Mexico...
  30. Zeng Y, Wang H, Zuo W, Zheng B, Yang T, Dai H, et al. A fatty acid glycoside from a marine-derived fungus isolated from mangrove plant Scyphiphora hydrophyllacea. Mar Drugs. 2012;10:598-603 pubmed publisher
    ..Antimicrobial assay showed compound 1 possessed modest inhibitory effect on Saphylococcus aureus and methicillin-resistant S. aureus (MRSA) using the filter paper disc agar diffusion method...
  31. Gonzalez C, Ornelas J, Jiménez L. Between-year changes in functional gender expression of Palicourea padifolia (Rubiaceae), a distylous, hummingbird-pollinated shrub. Ann Bot. 2005;95:371-8 pubmed
    ..Between-year variation in flower and fruit production of hummingbird-pollinated Palicourea padifolia (Rubiaceae) was examined, focusing on functional gender expression of long- and short-styled morphs and comparing their ..
  32. Massinga P, Johnson S, Harder L. Heteromorphic incompatibility and efficiency of pollination in two distylous Pentanisia species (Rubiaceae). Ann Bot. 2005;95:389-99 pubmed
    ..Distyly and its pollination consequences were examined in two Pentanisia species with long-tubed flowers which are pollinated almost exclusively by butterflies...
  33. Soobrattee M, Bahorun T, Neergheen V, Googoolye K, Aruoma O. Assessment of the content of phenolics and antioxidant actions of the Rubiaceae, Ebenaceae, Celastraceae, Erythroxylaceae and Sterculaceae families of Mauritian endemic plants. Toxicol In Vitro. 2008;22:45-56 pubmed
    ..The polyphenolic composition and antioxidant potential of Mauritian endemic plants of the Rubiaceae, Ebenaceae, Celastraceae, Erythroxylaceae and Sterculaceae family were determined...
  34. Muktar M, Osman N, Awang K, Hazni H, Qureshi A, Hadi A, et al. Neonaucline, a new indole alkaloid from the leaves of Ochreinauclea maingayii (Hook. f.) Ridsd. (Rubiaceae). Molecules. 2011;17:267-74 pubmed publisher
    ..3), harmane, benzamide, cinnamide and blumenol A-were isolated from the leaves of Ochreinauclea maingayii (Rubiaceae). In addition to that of compound 1, (13)C-NMR data of cadamine (2) and naucledine (3) were also reported...
  35. Hereford J, Moriuchi K. Variation among populations of Diodia teres (Rubiaceae) in environmental maternal effects. J Evol Biol. 2005;18:124-31 pubmed
    ..We conclude that variation among populations in EME may be an unrecognized component of local adaptation, and that attempts to control maternal effects by statistically accounting for variation in seed weight may be ineffective...
  36. Verstraete B, Van Elst D, Steyn H, Van Wyk B, Lemaire B, Smets E, et al. Endophytic bacteria in toxic South African plants: identification, phylogeny and possible involvement in gousiekte. PLoS ONE. 2011;6:e19265 pubmed publisher
    South African plant species of the genera Fadogia, Pavetta and Vangueria (all belonging to Rubiaceae) are known to cause gousiekte (literally 'quick disease'), a fatal cardiotoxicosis of ruminants characterised by acute heart failure ..
  37. Ngo Bum E, Taiwe G, Moto F, Ngoupaye G, Nkantchoua G, Pelanken M, et al. Anticonvulsant, anxiolytic, and sedative properties of the roots of Nauclea latifolia Smith in mice. Epilepsy Behav. 2009;15:434-40 pubmed publisher
    Root bark of Nauclea latifolia Smith (Rubiaceae) was evaluated for its anticonvulsant, anxiolytic, and sedative activity in mice...
  38. Lau P, Bosque C. Pollen flow in the distylous Palicourea fendleri (Rubiaceae): an experimental test of the Disassortative Pollen Flow Hypothesis. Oecologia. 2003;135:593-600 pubmed
    ..We discuss the relevance of the latter findings in relation to other studies of pollen flow in heterostylous species...
  39. Jansen S, Watanabe T, Dessein S, Smets E, Robbrecht E. A comparative study of metal levels in leaves of some Al-accumulating Rubiaceae. Ann Bot. 2003;91:657-63 pubmed
    Concentrations of Al, Si, Fe, Mn, Cu and Ca were analysed in leaves of ten Rubiaceae species, most of which are Al accumulators, and these were compared with concentrations in one species of Melastomataceae...
  40. Cardona Zuleta L, Cavalheiro A, Siqueira Silva D, Furlan M, Marx Young M, Albuquerque S, et al. seco-iridoids from Calycophyllum spruceanum (Rubiaceae). Phytochemistry. 2003;64:549-53 pubmed
    ..0, 90.2, 74,2 and 84.9 microg/mL, respectively and were compared to the standard gentian violet (IC(50) 7.5 microg/ml)...
  41. Church S. Molecular phylogenetics of Houstonia (Rubiaceae): descending aneuploidy and breeding system evolution in the radiation of the lineage across North America. Mol Phylogenet Evol. 2003;27:223-38 pubmed
    ..DNA sequence variation was used to infer evolutionary relationships within and among members of Houstonia (Rubiaceae) and other closely related genera in North America...
  42. Malcomber S. Phylogeny of Gaertnera Lam. (Rubiaceae) based on multiple DNA markers: evidence of a rapid radiation in a widespread, morphologically diverse genus. Evolution. 2002;56:42-57 pubmed
    Phylogenetic relationships among 28 of the 68 species of the paleotropical genus Gaertnera (Rubiaceae) and two related genera were inferred from nucleotide sequence variation in four nuclear DNA (nDNA) markers: the internal transcribed ..
  43. Ikpi D, Obembe A, Nku C. Aqueous leaf extract of Rothmannia longiflora improves basal metabolic rate and electrolyte parameters in alloxan-induced diabetic rats. Niger J Physiol Sci. 2009;24:67-71 pubmed
    ..This suggests that oral administration of Rothmannia longiflora might be beneficial for the restoration of basal metabolic rate and improvement of electrolyte profile in diabetes mellitus. ..
  44. Tu T, Sun H, Bartholomew B, Nie Z. A cytological study on Kelloggia (Rubiaceae), an intercontinental disjunct genus between eastern Asia and western North America. J Plant Res. 2006;119:397-400 pubmed
    A cytological study was carried out for the first time on four populations of the only two species of Kelloggia (Rubiaceae), which occur disjunctly in eastern Asia (K. chinensis Franch.) and western North America (K. galioides Torr.)...
  45. Piegang B, Tigoufack I, Ngnokam D, Achounna A, Watcho P, Greffrath W, et al. Cycloartanes from Oxyanthus pallidus and derivatives with analgesic activities. BMC Complement Altern Med. 2016;16:97 pubmed publisher
    The leaves of Oxyanthus pallidus Hiern (Rubiaceae) are extensively used in the west region of Cameroon as analgesic...
  46. Biswas D, Misbahuddin M, Roy U, Francis R, Bose S. Effect of additives on fiber yield improvement for kraft pulping of kadam (Anthocephalus chinensis). Bioresour Technol. 2011;102:1284-8 pubmed publisher
    ..The viscosities and the physical strength properties of the pulps with kappa numbers 16-19 were comparable to kraft although there was a minor decrease in tensile strength for the kraft/MAQ pulp. ..
  47. Verstraete B, Janssens S, Rønsted N. Non-nodulated bacterial leaf symbiosis promotes the evolutionary success of its host plants in the coffee family (Rubiaceae). Mol Phylogenet Evol. 2017;113:161-168 pubmed publisher
    ..Within some clades of Rubiaceae (coffee family), a specific plant-bacteria interaction exists in which non-pathological endophytes are present ..
  48. Niño J, Hernández J, Correa Y, Mosquera O. In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora. Mem Inst Oswaldo Cruz. 2006;101:783-5 pubmed
    The methanol extracts from five different plant families (Asteraceae, Euphorbiaceae, Melastomataceae, Rubiaceae, and Solanaceae) collected at Regional Natural Park Ucumarí (Colombia), were screened for their acetylcholinesterase ..
  49. Sutovska M, Franova S, Priseznaková L, Nosalova G, Togola A, Diallo D, et al. Antitussive activity of polysaccharides isolated from the Malian medicinal plants. Int J Biol Macromol. 2009;44:236-9 pubmed publisher
    ..celtidifolia did not influence the experimentally induced cough as well as reactivity of airways smooth muscle despite of the fact that the water-ethanol extract is recommended for cough therapy in Mali in the form of syrup. ..
  50. Tigoufack I, Ngnokam D, Tapondjou L, Harakat D, Voutquenne L. Cycloartane glycosides from leaves of Oxyanthus pallidus. Phytochemistry. 2010;71:2182-6 pubmed publisher
    ..The structures of pallidiosides A-C were assigned on the basis of spectral studies and comparison with published literature data. The known compounds were identified by means of Co TLC and confirmed by their physical constants. ..
  51. Chomicki G, Janda M, Renner S. The assembly of ant-farmed gardens: mutualism specialization following host broadening. Proc Biol Sci. 2017;284: pubmed publisher
    ..ferns (Lecanopteris) and flowering plants in the Apocynaceae (Hoya and Dischidia) and Rubiaceae (Myrmecodia, Hydnophytum, Anthorrhiza, Myrmephytum and Squamellaria)...
  52. Wiart C, Hannah A, Yusof M, Hamimah H, Sulaiman M. Growth inhibition of foodborne and nosocomial pathogens by aqueous fraction of bearded Argostemma (Argostemma involucratum Hemsl., Rubiaceae). J Herb Pharmacother. 2005;5:97-102 pubmed
    The crude methanol extract of Bearded Argostemma (Argostemma involucratum Hemsl., Rubiaceae) showed a good and broad spectrum of antibacterial activity against both Gram-negative and Gram-positive bacteria...
  53. Taiwe G, Moto F, Pale S, Kandeda A, Dawe A, Kouemou N, et al. Extracts of Feretia apodanthera Del. demonstrated anticonvulsant activities against seizures induced by chemicals and maximal electroshock. Epilepsy Res. 2016;127:30-39 pubmed publisher
    Extracts of Feretia apodanthera Del. (Rubiaceae) have been extensively used in traditional Cameroonian medicine to treat a variety of diseases, including some neurological disorders...
  54. Dávila Lara A, Affenzeller M, Tribsch A, Diaz V, Comes H. AFLP diversity and spatial structure of Calycophyllum candidissimum (Rubiaceae), a dominant tree species of Nicaragua's critically endangered seasonally dry forest. Heredity (Edinb). 2017;119:275-286 pubmed publisher
  55. Pandey A, Negi P. Traditional uses, phytochemistry and pharmacological properties of Neolamarckia cadamba: A review. J Ethnopharmacol. 2016;181:118-35 pubmed publisher
    ..One such under-explored plant is an evergreen tropical tree Neolamarckia cadamba (Roxb.) Bosser (Rubiaceae)...
  56. Willcox M. Improved traditional phytomedicines in current use for the clinical treatment of malaria. Planta Med. 2011;77:662-71 pubmed publisher
    ..Asteraceae), Cinchona bark (Rubiaceae), Cryptolepis sanguinolenta (Lindl.) Schltr...
  57. Abdullah N, Thomas N, Sivasothy Y, Lee V, Liew S, Noorbatcha I, et al. Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study. Int J Mol Sci. 2016;17:143 pubmed publisher
    ..The in silico molecular docking study which was used to determine the binding interactions revealed that the ursolic acid analog 22 had a strong affinity towards human hyaluronidase. ..
  58. Mesia K, Tona L, Mampunza M, Ntamabyaliro N, Muanda T, Muyembe T, et al. Antimalarial efficacy of a quantified extract of Nauclea pobeguinii stem bark in human adult volunteers with diagnosed uncomplicated falciparum malaria. Part 1: a clinical phase IIA trial. Planta Med. 2012;78:211-8 pubmed publisher
  59. Khwanchuea R, Jansakul C, Mulvany M, Queiroz E, Hostettmann K. Cardiovascular effects of an n-butanol extract from fresh fruits of Randia siamensis. Biol Pharm Bull. 2007;30:96-104 pubmed
    ..The hypotensive activity results from the release of nitric oxide causing dilatation of the blood vessels. The present data support the folklore therapeutic uses of this plant. ..
  60. Zhao X, Tong T, Li H, Lu H, Ren J, Zhang A, et al. Characterization of hemicelluloses from Neolamarckia cadamba (Rubiaceae) during xylogenesis. Carbohydr Polym. 2017;156:333-339 pubmed publisher
    ..02N NaCl). Xylan in the middle and basal segment stems had higher molecular weights. Our findings show that during xylogenesis in N. cadamba, changes are observed in xylan content and molecular weight. ..
  61. Karim A, Mekhfi H, Ziyyat A, Legssyer A, Bnouham M, Amrani S, et al. Anti-diarrhoeal activity of crude aqueous extract of Rubia tinctorum L. roots in rodents. J Smooth Muscle Res. 2010;46:119-23 pubmed
    The anti-diarrhoeal effect of aqueous extract of Rubia tinctorum L. (Rubiaceae) roots in rodents was examined...
  62. Ruiz Mesía L, Ruiz Mesía W, Reina M, Martínez Díaz R, de Inés C, Guadaño A, et al. Bioactive cinchona alkaloids from Remijia peruviana. J Agric Food Chem. 2005;53:1921-6 pubmed
    ..two new ones, acetylcupreine (4) and N-ethylquinine (5), have been isolated from the bark of Remijia peruviana (Rubiaceae). Their stereochemical structures were established by high resolution NMR spectroscopy...
  63. Zhao Z, Matsunami K, Otsuka H, Shinzato T, Takeda Y. Tareciliosides A--G: Cycloartane glycosides from leaves of Tarenna gracilipes (HAY.) OHWI. Chem Pharm Bull (Tokyo). 2008;56:1153-8 pubmed
    ..Their structures were elucidated through a combination of spectroscopic analyses. ..
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    ..boninensis, G. parvifolia, and G. umbellata, only G. boninensis is androdioecious, whereas the others are dioecious. Thus, the androdioecious sexual system of G. boninensis may have evolved from dioecy. ..
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    ..the phytochemical constituents and the aphrodisiac potential of the aqueous extract of Fadogia agrestis (Rubiaceae) stem in male albino rats. The aqueous stem extract of the plant was screened for phytochemical constituents...
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    Heterophyllaea pustulata (Rubiaceae), a South American genus, is a phototoxic shrub that grows in the Andean mountain range of the northwest of Argentina, popularly known as "cegadera"...
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    The species of the genus Palicourea (Rubiaceae family) is well-known for its toxicity towards animals, particularly livestock...
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    ..These markers will facilitate genetic diversity studies of P. padifolia across its distribution range and facilitate investigations on the evolution of its breeding system. ..
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    ..These results indicate the presence of psychoactive substances in the aqueous extract of the root bark of Nauclea latifolia...
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    ..The aim of the study was to evaluate the in vitro antimicrobial activities of three plants that small-holder farmers in Zimbabwe used to manage bovine dermatophilosis...
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    ..Observed lethal concentrations (LC(50) and LC(90)) were 1.08 and 2.76 ppm for gold nanoparticles and 21.82 and 79.52 ppm for the third instar of C. quinquefasciatus...
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    ..Different types of closure of the donor site have been advocated to reduce donor-site complications. In our practice, a V-Y closure with a local full-thickness skin graft (FTG) is performed generally...
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    ..Augustine, Florida. Laboratory evaluations of boric acid sugar baits applied to the plant Pentas lanceolata (Rubiaceae) demonstrated 100 and 92% mortality of A. albopictus at day 7 and 14, respectively...
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    ..A new compound was isolated and identified, which was 3, 8-dihydroxy-1-methoxy-2-methoxymethyl-9,10-anthraquinone (I). Compound I is a new anthraquinone, namely lasianthurin...
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    ..While, compounds 1 and 5-7 showed strong inhibitory activity against RLAR with IC(50) values of 3.35, 3.04, 6.39, and 2.05 microM, respectively...
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    ..Merr. (Rubiaceae) were achieved by 1D and 2D techniques such as DEPT, HMBC, HMQC, COSY and NOESY.
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    ..The practical usefulness of the present technique was demonstrated by its application to a few natural products...
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    ..Ixora parviflora is a member of the flavonoid-rich Rubiaceae family of flowering plants and used as folk medicine in India...