ardisia

Summary

Summary: A plant genus of the family MYRSINACEAE. Members contain ardisiacrispins (oleanane triterpenoid saponins), ardicrenin, and cyclamiretin.

Top Publications

  1. Song L, Zhou W. [Content determination of bergenin in Ardisia pusilla by HPLC]. Zhong Yao Cai. 2007;30:422-3 pubmed
    To determine the content of bergenin in Ardisia pusilla.
  2. Li C, Yue D, Bu P, Sun Y. Two novel compounds from Ardisia punctata Lindl. Yao Xue Xue Bao. 2007;42:959-63 pubmed
    To study the chemical constituents of Ardisia punctata, compounds were isolated with a combination of multi-chromatography. Their structures were determined on the basis of spectral analysis and comparison to those of the known compounds...
  3. Zhang Y, Qu Y, Zhang J, Wang X. Ardipusilloside I purified from Ardisia pusilla competitively binds VEGFR and induces apoptosis in NCI-H460 cells. Phytomedicine. 2010;17:519-26 pubmed publisher
    The present study was to evaluate the effects of Ardipusilloside I isolated from Ardisia pusilla on the growth, vascular endothelial growth factor receptor (VEGFR) expression and apoptosis of NCI-H460 cell line by MTT, ELISA and flow ..
  4. Chang X, Li W, Jia Z, Satou T, Fushiya S, Koike K. Biologically active triterpenoid saponins from Ardisia japonica. J Nat Prod. 2007;70:179-87 pubmed
    ..15), H (16), I (17), J (18), and K (19), together with 10 known saponins, were isolated from the whole plants of Ardisia japonica...
  5. Liu D, Wang N, Zhang X, Gao H, Yao X. Two new triterpenoid saponins from Ardisia crenata. J Asian Nat Prod Res. 2007;9:119-27 pubmed
    ..new triterpenoid saponins, ardisicrenoside K (1) and ardisicrenoside L (2), have been isolated from the roots of Ardisia crenata Sims...
  6. Li Y, Li J, Shen Q, Hu L. Benzoquinones from Ardisia japonica with inhibitory activity towards human protein tyrosine phosphatase 1B (PTP1B). Chem Biodivers. 2007;4:961-5 pubmed
    From the whole plant of Ardisia japonica, four [1,4]benzoquinones were isolated by means of bioassay-directed fractionation of the EtOH extract. Apart from the two known compounds maesanin (1) and its congener 2, two new benzoquinones, i...
  7. Tian Y, Tang H, Qiu F, Wang X, Chen X, Wen A. Triterpenoid saponins from Ardisia pusilla and their cytotoxic activity. Planta Med. 2009;75:70-5 pubmed publisher
    ..with two known saponins, ardisiacrispin B (1) and ardisiacrispin A (2), were isolated from the whole plants of Ardisia pusilla A. DC. Their structures were elucidated by extensive spectral analysis and chemical evidence...
  8. Ku C, Hu J, Kuo C. Complete plastid genome sequence of the basal asterid Ardisia polysticta Miq. and comparative analyses of asterid plastid genomes. PLoS ONE. 2013;8:e62548 pubmed publisher
    b>Ardisia is a basal asterid genus well known for its medicinal values and has the potential for development of novel phytopharmaceuticals...
  9. Kobayashi H, de Mejia E. The genus Ardisia: a novel source of health-promoting compounds and phytopharmaceuticals. J Ethnopharmacol. 2005;96:347-54 pubmed
    Approximately 500 species of Ardisia (Myrsinaceae) are found throughout tropical and subtropical regions of the world. Several of those Ardisia species have been used as ornamental plants, food and medicines...

More Information

Publications78

  1. Chandra S, De Mejia Gonzalez E. Polyphenolic compounds, antioxidant capacity, and quinone reductase activity of an aqueous extract of Ardisia compressa in comparison to mate (Ilex paraguariensis) and green (Camellia sinensis) teas. J Agric Food Chem. 2004;52:3583-9 pubmed
    Aqueous extracts of the leaves of Ardisia compressa (AC) have been used in folk medicine to treat various liver disorders including liver cancer...
  2. Lemaire B, Smets E, Dessein S. Bacterial leaf symbiosis in Ardisia (Myrsinoideae, Primulaceae): molecular evidence for host specificity. Res Microbiol. 2011;162:528-34 pubmed publisher
    The association between bacteria and leaves in Ardisia has been described as a cyclic and obligate symbiosis in which bacteria are maintained throughout all stages of the plant's life cycle to guarantee normal growth and survival of the ..
  3. Gonzalez de Mejia E, Ramirez Mares M, Nair M. Topoisomerase I and II enzyme inhibitory aqueous extract of Ardisia compressa and ardisin protect against benomyl oxidation of hepatocytes. J Agric Food Chem. 2002;50:7714-9 pubmed
    Tea preparations of Ardisia compressa (AC) have been used in folk medicine against liver disorders...
  4. Newell A, Yousef G, Lila M, Ramirez Mares M, de Mejia E. Comparative in vitro bioactivities of tea extracts from six species of Ardisia and their effect on growth inhibition of HepG2 cells. J Ethnopharmacol. 2010;130:536-44 pubmed publisher
    b>Ardisia species, notably A. compressa, are used in some regions of the world as food or in traditional medicine for prevention and treatment of certain health conditions including liver disease...
  5. Li Q, Li W, Hui L, Zhao C, He L, Koike K. 13,28-Epoxy triterpenoid saponins from Ardisia japonica selectively inhibit proliferation of liver cancer cells without affecting normal liver cells. Bioorg Med Chem Lett. 2012;22:6120-5 pubmed publisher
    Twenty 13,28-epoxy and related triterpenoid saponins from Ardisia japonica were evaluated for their anti-proliferative activity on human liver cancer cells and normal liver cells...
  6. Hamsin D, Hamid R, Yazan L, Taib C, Ting Y. The hexane fraction of Ardisia crispa Thunb. A. DC. roots inhibits inflammation-induced angiogenesis. BMC Complement Altern Med. 2013;13:5 pubmed publisher
    b>Ardisia crispa (Myrsinaceae) is used in traditional Malay medicine to treat various ailments associated with inflammation, including rheumatism...
  7. Chang H, Lin Y, Lee S, Yang C, Lin W, Tsai I, et al. Cytotoxic alkyl benzoquinones and alkyl phenols from Ardisia virens. Phytochemistry. 2009;70:2064-71 pubmed publisher
    Bioassay-guided fractionation of roots and stems of Ardisia virens Kurz (Myrsinaceae) led to isolation of fourteen compounds, (2'R)-6-(2'-acetoxypentadecyl)-5-hydroxy-2-methoxy-1,4-benzoquinone (1), (2'R)-6-(2'-acetoxytridecyl)-5-hydroxy-..
  8. Roslida A, Fezah O, Yeong L. Suppression of DMBA/croton oil-induced mouse skin tumor promotion by Ardisia Crispa root hexane extract. Asian Pac J Cancer Prev. 2011;12:665-9 pubmed
    b>Ardisia crispa (Family: Myrsinaceae) has been used as a traditional medicine for various ailments. Previous studies showed that Ardisia crispa possesses antimetastatic and anti-inflammatory properties...
  9. Zhu G, Wong B, Lu A, Bian Z, Zhang G, Chen H, et al. Alkylphenols from the roots of Ardisia brevicaulis induce G1 arrest and apoptosis through endoplasmic reticulum stress pathway in human non-small-cell lung cancer cells. Chem Pharm Bull (Tokyo). 2012;60:1029-36 pubmed
    From the roots of Ardisia brevicaulis DIELS, two new alkylphenol derivatives, named ardisiphenol E (2) and F (3), have been isolated together with a known alkylphenol, ardisiphenol D (1)...
  10. Zheng Z, Xu J, Feng Z, Zhang P. Cytotoxic triterpenoid saponins from the roots of Ardisia crenata. J Asian Nat Prod Res. 2008;10:833-9 pubmed publisher
    ..I (1), a new triterpenoid pentasaccharide with an unusual glycosyl glycerol side chain, was isolated from Ardisia crenata together with five closely related triterpenoid saponins...
  11. de Mejia E, Ramirez Mares M. Ardisia: health-promoting properties and toxicity of phytochemicals and extracts. Toxicol Mech Methods. 2011;21:667-74 pubmed publisher
    b>Ardisia species (Myrsinaceae) are found throughout tropical and subtropical regions of the world...
  12. Zaima K, Deguchi J, Matsuno Y, Kaneda T, Hirasawa Y, Morita H. Vasorelaxant effect of FR900359 from Ardisia crenata on rat aortic artery. J Nat Med. 2013;67:196-201 pubmed publisher
    A cyclic depsipeptide, FR900359, isolated from Ardisia crenata was evaluated for vasorelaxant effects on rat aortic arteries...
  13. Sumino M, Sekine T, Ruangrungsi N, Igarashi K, Ikegami F. Ardisiphenols and other antioxidant principles from the fruits of Ardisia colorata. Chem Pharm Bull (Tokyo). 2002;50:1484-7 pubmed
    ..ardisiphenols A-C (1-3) and a novel bergenin derivative, demethoxybergenin (10) were isolated from the fruits of Ardisia colorata (Myrsinaceae), together with known alkylresorcinols (4-6), embelin (7), myricetin (8), quercetin (9), ..
  14. Ramirez Mares M, Chandra S, de Mejia E. In vitro chemopreventive activity of Camellia sinensis, Ilex paraguariensis and Ardisia compressa tea extracts and selected polyphenols. Mutat Res. 2004;554:53-65 pubmed
    ..of (-) epigallocatechin gallate (EGCG), quercetin (Q), gallic acid (GA), green tea (GT, Camellia sinensis), ardisia tea (AT, Ardisia compressa) and mate tea (MT, Ilex paraguariensis) extracts were tested...
  15. de Mejia E, Chandra S, Ramírez Mares M, Wang W. Catalytic inhibition of human DNA topoisomerase by phenolic compounds in Ardisia compressa extracts and their effect on human colon cancer cells. Food Chem Toxicol. 2006;44:1191-203 pubmed
    ..In this study, the main objectives were to identify and characterize the phenolic compounds in Ardisia compressa tea (AC) responsible for topoisomerase inhibition using a bioassay directed approach and modern ..
  16. Li Y, Hu L, Lou F, Li J, Shen Q. PTP1B inhibitors from Ardisia japonica. J Asian Nat Prod Res. 2005;7:13-8 pubmed
    In bioassay-directed isolation from the whole plant of Ardisia japonica, sixteen known compounds: chrysophanol (1), physcion (2), oleanolic acid (3), euscaphic acid (4), tormentic acid (5), quercetin (6), quercitrin (7), myricitrin (8), ..
  17. Su S, Li Y, Ouyang Z, Chen J. [Advances in the study of triterpene constituents of Ardisia medicinal plants]. Zhong Yao Cai. 2003;26:144-8 pubmed
  18. Li M, Wei S, Xu B, Guo W, Liu D, Cui J, et al. Pro-apoptotic and microtubule-disassembly effects of ardisiacrispin (A+B), triterpenoid saponins from Ardisia crenata on human hepatoma Bel-7402 cells. J Asian Nat Prod Res. 2008;10:739-46 pubmed publisher
    Ardisiacrispin (A+B) is a mixture of ardisiacrispins A and B, derived from Ardisia crenata with a fixed proportion (2:1)...
  19. Ndontsa B, Tchinda A, Teponno R, Mpetga J, Frederich M, Tane P. Ardisikivuoside, a new triterpenoid saponin from Ardisia kivuensis (Myrsinaceae). Nat Prod Commun. 2012;7:515-6 pubmed
    Column chromatography of the n-butanol extract of the stem of Ardisia kivuensis (Myrsinaceae) led to the isolation of a new triterpenoid saponin, ardisikivuoside (1) {3-O-beta-D-xylopyranosyl-(1 --> 3)-beta-D-glucopyranosyl-(1 --> ..
  20. Huang J, Zhang H, Shimizu N, Takeda T. Ardisimamillosides G and H, two new triterpenoid saponins from Ardisia mamillata. Chem Pharm Bull (Tokyo). 2003;51:875-7 pubmed
    ..were isolated from the roots of Ardisia mamillata HANCE. Structure assignments were established on the basis of spectral data and chemical evidence.
  21. Ching J, Chua T, Chin L, Lau A, Pang Y, Jaya J, et al. Beta-amyrin from Ardisia elliptica Thunb. is more potent than aspirin in inhibiting collagen-induced platelet aggregation. Indian J Exp Biol. 2010;48:275-9 pubmed
    b>Ardisia elliptica Thunberg (Myrsinaceae) is a medicinal plant traditionally used for alleviating chest pains, treatment of fever, diarrhoea, liver poisoning and parturition complications...
  22. Chassagne F, Hul S, Deharo E, Bourdy G. Natural remedies used by Bunong people in Mondulkiri province (Northeast Cambodia) with special reference to the treatment of 11 most common ailments. J Ethnopharmacol. 2016;191:41-70 pubmed publisher
    ..During our survey, we also discovered a "new to science" plant species called Ardisia mondulkiriensis Hul and Chassagne, and we recorded for the second time the plant species recently described, ..
  23. Yeong L, Abdul Hamid R, Saiful Yazan L, Khaza Ai H, Mohtarrudin N. Low dose triterpene-quinone fraction from Ardisia crispa root precludes chemical-induced mouse skin tumor promotion. BMC Complement Altern Med. 2015;15:431 pubmed publisher
    ..Apart from its traditional usages against various ailments, Ardisia crispa (Family: Myrsinaceae) specifically its triterpene-quinone fraction (TQF) which was isolated from the root ..
  24. Chang H, Lin C, Chen Y, Wang H, Chan H, Hsieh S, et al. Secondary Metabolites of the Endophytic Fungus Lachnum abnorme from Ardisia cornudentata. Int J Mol Sci. 2016;17: pubmed publisher
    ..BCRC 09F0006, derived from the endemic plant, Ardisia cornudentata Mez...
  25. Chatatikun M, Chiabchalard A. Thai plants with high antioxidant levels, free radical scavenging activity, anti-tyrosinase and anti-collagenase activity. BMC Complement Altern Med. 2017;17:487 pubmed publisher
    ..The ethanol leaf extract of Ardisia elliptica Thunb...
  26. Cao W, Wang Y, Wang P, Lei W, Feng B, Wang X. Ardipusilloside-I Metabolites from Human Intestinal Bacteria and Their Antitumor Activity. Molecules. 2015;20:20569-81 pubmed publisher
    Ardipusilloside-I (ADS-I) is a triterpenoid saponin extracted from Ardisia pusilla DC, and has been demonstrated to have potent antitumor activity. However, ADS-I metabolism in humans has not been investigated...
  27. Liu H, Zhao F, Yang R, Wang M, Zheng M, Zhao Y, et al. Dimeric 1,4-benzoquinone derivatives and a resorcinol derivative from Ardisia gigantifolia. Phytochemistry. 2009;70:773-8 pubmed publisher
    ..F, G, H, and I, as well as one resorcinol derivative and four known compounds, were isolated from rhizomes of Ardisia gigantifolia. Their structures were established by means of spectroscopic analyses...
  28. Crüsemann M, Reher R, Schamari I, Brachmann A, Ohbayashi T, Kuschak M, et al. Heterologous expression, biosynthetic studies and ecological function of the selective Gq-signaling inhibitor FR900359. Angew Chem Int Ed Engl. 2017;: pubmed publisher
    The cyclic depsipeptide FR900359 (FR), isolated from the tropical plant Ardisia crenata, displays a strong and selective inhibition of Gq proteins, making it an indispensable pharmacological tool to study Gq-related processes, as well as ..
  29. Mohanta Y, Biswas K, Panda S, Bandyopadhyay J, De D, Jayabalan R, et al. Phyto-assisted synthesis of bio-functionalised silver nanoparticles and their potential anti-oxidant, anti-microbial and wound healing activities. IET Nanobiotechnol. 2017;11:1027-1034 pubmed publisher
    Bio- synthesis of silver nanoparticles (AgNPs) was made by using the aqueous leaf extract of Ardisia solanacea. Rapid formation of AgNPs was observed from silver nitrate upon treatment with the aqueous extract of A. solanacea leaf...
  30. Wang R, Gu Y, Zhang W, Yan X, Jin L, Wang X. Inhibition of tumor-induced angiogenesis and its mechanism by ardipusilloside I purified from Ardisia pusilla. J Asian Nat Prod Res. 2012;14:55-63 pubmed publisher
    The aim of this study was to evaluate the effects of ardipusilloside I isolated from Ardisia pusilla on tumor angiogenesis and its mechanism of action...
  31. Mu L, Feng J, Liu P. A new bergenin derivative from the rhizome of Ardisia gigantifolia. Nat Prod Res. 2013;27:1242-5 pubmed publisher
    ..11-O-syringylbergenin (3), 11-O-Galloylbergenin (4), 4-O-Galloylbergenin (5) and bergenin (6) were isolated from Ardisia gigantifolia Stapf...
  32. Zheng Y, Deng Y, Wu F. Ardisinones A-E, novel diarylundecanones from Ardisia arborescens. J Nat Prod. 2004;67:1617-9 pubmed
    A phytochemical study on an ethanol extract of Ardisia arborescens resulted in the isolation of five new diarylundecanones, named ardisinones A-E (1-5)...
  33. Nesterov A, Hong M, Hertel C, Jiao P, Brownell L, Cannon E. Screening a plant extract library for inhibitors of cholecystokinin receptor CCK1 pathways. J Biomol Screen. 2010;15:518-27 pubmed publisher
    ..The selectivity of inhibition was tested against a panel of Galpha(q/11), Galpha(s), and Galpha(i/0)-coupled receptors. These studies led to the identification of a novel Galpha(q/11)-selective inhibitor...
  34. Zhang P, Zheng C, Wu C, Sheng Y, Zhang J. Mass spectral fragmentation analysis of triterpene saponins from Ardisia crenata Sims by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. J Asian Nat Prod Res. 2010;12:64-9 pubmed publisher
    ..FTICR-MS) technique to study the characteristic mass fragmentation patterns of eight triterpene saponins from Ardisia crenata Sims...
  35. Wong S, Chen C, Huang H, Weng J. Using combined measurements for comparison of light induction of stomatal conductance, electron transport rate and CO2 fixation in woody and fern species adapted to different light regimes. Tree Physiol. 2012;32:535-44 pubmed publisher
    ..We studied three woody species (Alnus formosana, Ardisia crenata and Ardisia cornudentata) and four fern species (Pyrrosia lingus, Asplenium antiquum, Diplazium donianum ..
  36. Ma C, Luo M, Lin L, Li C, Wang Z, Cheng Y. [Chemical constituents of Ardisia punctata]. Zhongguo Zhong Yao Za Zhi. 2012;37:3422-5 pubmed
    To study chemical constituents of Ardisia punctata,in order to find pioneering compounds.
  37. Wen P, Zhang X, Yang Z, Wang N, Yao X. Four new triterpenoid saponins from Ardisia gigantifolia Stapf. and their cytotoxic activity. J Asian Nat Prod Res. 2008;10:873-80 pubmed publisher
    ..4), along with one known triterpene saponin and ardisiacrispin A (5) were isolated from the rhizome of Ardisia gigantifolia. Their structures were established with the help of extensive spectroscopic techniques...
  38. Wang X, Tang S, Zhai H, Duan H. [Studies on anti-tumor metastatic constituents from Ardisia Crenata]. Zhongguo Zhong Yao Za Zhi. 2011;36:881-5 pubmed
    To study the anti-tumor metastatic constituents from Ardisia Crenata.
  39. Li C, Yue D, Bu P, Sun Y. [Chemical constituents from roots of Ardisia punctata]. Zhongguo Zhong Yao Za Zhi. 2006;31:562-5 pubmed
    To study the chemical constituents from the roots of Ardisia punctata.
  40. Song H, Wang J, Zhang R, Liu X, Yuan G, Wei C, et al. In vivo metabolism study of bergenin in rats by HPLC-QTOF mass spectrometry. Biomed Chromatogr. 2013;27:1398-405 pubmed publisher
    Bergenin is the major component of Ardisia creanta sims and Rodgersia sambucifolia hemsl with many biological activities...
  41. Ching J, Soh W, Tan C, Lee J, Tan J, Yang J, et al. Identification of active compounds from medicinal plant extracts using gas chromatography-mass spectrometry and multivariate data analysis. J Sep Sci. 2012;35:53-9 pubmed publisher
    ..fractionation were used to prepare different extracts and fractions from the leaves of a medicinal plant, Ardisia elliptica...
  42. Li C, Yue D, Bu P, Sun Y. Three new belamcandaquinones from Ardisia punctata. Yao Xue Xue Bao. 2006;41:830-4 pubmed
    To study the chemical constituents of Ardisia punctata.
  43. Nordin M, Abdul Kadir A, Zakaria Z, Abdullah R, Abdullah M. In vitro investigation of cytotoxic and antioxidative activities of Ardisia crispa against breast cancer cell lines, MCF-7 and MDA-MB-231. BMC Complement Altern Med. 2018;18:87 pubmed publisher
    b>Ardisia crispa Thunb. D.C is used mostly in some parts of the Asian region by traditional practitioners to treat certain diseases associated with oxidative stress and inflammation including cancer and rheumatism...
  44. Sulaiman H, Hamid R, Ting Y, Othman F. Anti-tumor effect of Ardisia crispa hexane fraction on 7, 12-dimethylbenz[?]anthracene-induced mouse skin papillomagenesis. J Cancer Res Ther. 2012;8:404-10 pubmed publisher
    b>Ardisia crispa Thunb. A. DC (Myrsinaceae) or locally known as hen's eyes has been used in local folk medicine as a remedy in various illnesses. Previously, it has been reported to inhibit various inflammatory diseases...
  45. Raga D, Herrera A, Ragasa C. Angio-suppressive triterpenoids from Ardisia cf. elliptica (subgenus Tinus) on duck (Anas platyrynchos L.) chorioallantoic membrane. Chin J Nat Med. 2013;11:128-38 pubmed publisher
    The dichloromethane extract of the air-dried leaves of Ardisia cf. elliptica (subgenus Tinus) afforded a mixture of bauerenol (1a), ?-amyrin (1b) and ?-amyrin (1c). Their structures were identified by NMR spectroscopy...
  46. Mu L, Wei N, Liu P. Cytotoxic triterpenoid saponins from Ardisia gigantifolia. Planta Med. 2012;78:617-21 pubmed publisher
    ..Three new triterpenoid saponins, 1- 3, together with two known saponins, 4 and 5, were isolated from the rhizome of Ardisia gigantifolia. Their structures were elucidated by 1D and 2D NMR spectroscopic studies...
  47. Nikolovska Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller P, et al. Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database. J Med Chem. 2004;47:2430-40 pubmed
    ..followed by biochemical testing of selected candidate compounds, we discovered embelin from the Japanese Ardisia herb as a small-molecular weight inhibitor that binds to the XIAP BIR3 domain...
  48. Ma M, Liu J, Pu S. [Tissue culture and plant regeneration of Ardisia crenata]. Zhongguo Zhong Yao Za Zhi. 2009;34:2043-6 pubmed
    Our research studied the fast-breeding technology of Ardisia crenata sims by using tissue culture and provided the scientific foundation for industry production.
  49. Chang C, Chang H, Peng C, Lee S, Chen I. Antitubercular resorcinol analogs and benzenoid C-glucoside from the roots of Ardisia cornudentata. Planta Med. 2011;77:60-5 pubmed publisher
    Bioassay-guided fractionation of the roots of Ardisia cornudentata Mez (Myrsinaceae) led to the isolation of three new compounds, 3-methoxy-2-methyl-5-pentylphenol (1), 3-methoxy-2-methyl-5-(1'-ketopentyl)phenol (2), and cornudoside (3), ..
  50. Deng Y, Lu C, Guo D, Mei L. [Studies on the chemical constituents of Ardisia tenera]. Zhong Yao Cai. 2011;34:380-3 pubmed
    To investigate the chemical constituents of Ardisia tenera Mez.
  51. Wang X, Cui H, Wang R, Huan M, Zhang B, Zhang W, et al. Metabolism and pharmacokinetic study of ardipusilloside I in rats. Planta Med. 2012;78:565-74 pubmed publisher
    Ardipusilloside I, extracted from ARDISIA PUSILLA A.DC, effectively inhibits the progression of several cancers in animal models and is a potential anti-cancer drug candidate...
  52. Bao L, Wang M, Zhao F, Zhao Y, Liu H. Two new resorcinol derivatives with strong cytotoxicity from the roots of Ardisia brevicaulis Diels. Chem Biodivers. 2010;7:2901-7 pubmed publisher
    ..and (22E)-24-ethyl-5?-cholesta-7,22-dien-3?-ol were isolated from the MeOH extract of the roots of Ardisia brevicaulis Diels...
  53. Li Y, Su M, Cen Y, Zhang X, Dai Y, Ye W. [Study on the chemical constituents of Ardisia chinensis]. Zhong Yao Cai. 2006;29:331-3 pubmed
    The chemical constituents of Ardisia chinensis, which traditionally used in the area of Yao minority in Southern China, were analyzed and characterized...
  54. Dat N, Bae K, Wamiru A, McMahon J, Le Grice S, Bona M, et al. A dimeric lactone from Ardisia japonica with inhibitory activity for HIV-1 and HIV-2 ribonuclease H. J Nat Prod. 2007;70:839-41 pubmed
    A new dimeric lactone, ardimerin digallate (1), was isolated from the whole plants of Ardisia japonica, along with six known constituents...
  55. Mu L, Huang X, Guo D, Dong X, Liu P. A new triterpenoid saponin from Ardisia gigantifolia. J Asian Nat Prod Res. 2013;15:1123-9 pubmed publisher
    ..1), along with four known triterpenoids (2-5), was isolated from the rhizomes of Ardisia gigantifolia. Their structures were elucidated by spectroscopic methods...
  56. Zheng Y, Wu F. Resorcinol derivatives from Ardisia maculosa. J Asian Nat Prod Res. 2007;9:545-9 pubmed
    ..and triterpenoids, a new resorcinol (1) and a known resorcinol (2) have been isolated from ethanol extract of Ardisia maculosa for the first time...
  57. Hamid R, Othman F, Anthony J, Ting Y. Chemopreventive effect of Ardisia crispa hexane fraction on the peri-initiation phase of mouse skin tumorigenesis. Med Princ Pract. 2013;22:357-61 pubmed publisher
    To investigate the chemopreventive effect of the hexane extract of Ardisia crispa during the peri-initiation phase of mouse skin tumorigenesis.
  58. Tang H, Yun J, Lin H, Chen X, Wang X, Cheng G. Two new triterpenoid saponins cytotoxic to human glioblastoma U251MG cells from Ardisia pusilla. Chem Biodivers. 2009;6:1443-52 pubmed publisher
    ..together with one known saponin, ardisiacrispin B(3), were isolated from the whole plants of Ardisia pusilla A. DC. Their structures were deduced by extensive spectral analysis and chemical evidences...
  59. Pu L, Yuan X, Tang T. [Analysis of volatile oil from Ardisia brevicaulis]. Zhong Yao Cai. 2009;32:1694-7 pubmed
    To analyze and compare the compounds in the essential oil from the leaves and roots of Ardisia brevicaulis.
  60. Kubo T. [The etymological study of mudan and shaoyao in Chinese herbal medicine (Part 1). A Comparative Study of mudan and Ardisia spp]. Yakushigaku Zasshi. 2011;46:83-90 pubmed
    ..investigation of this issue has already been published, and reached the conclusion that mudan used to refer to Ardisia spp. However, further verifications looking at different aspects are required...
  61. Chen L, Zhao F, Wang Y, Zhao L, Li Q, Liu H. Antitumor effect of resorcinol derivatives from the roots of Ardisia brevicaulis by inducing apoptosis. J Asian Nat Prod Res. 2011;13:734-43 pubmed publisher
    ..4), 5-pentadecylresorcinol (5), 5-tridecylresorcinol (6), have been isolated from the roots of Ardisia brevicaulis in our previous work...
  62. Kikuchi H, Ohtsuki T, Koyano T, Kowithayakorn T, Sakai T, Ishibashi M. Death receptor 5 targeting activity-guided isolation of isoflavones from Millettia brandisiana and Ardisia colorata and evaluation of ability to induce TRAIL-mediated apoptosis. Bioorg Med Chem. 2009;17:1181-6 pubmed publisher
    ..Furthermore, a MeOH extract of the bark of Ardisia colorata markedly enhanced DR5 activity in this screening system. Bioassay-guided fractionation of A...
  63. Yeong L, Hamid R, Yazan L, Khaza Ai H. Isolation of a quinone-rich fraction from Ardisia crispa roots and its attenuating effects on murine skin tumorigenesis. Asian Pac J Cancer Prev. 2013;14:2301-5 pubmed
    b>Ardisia crispa (Family: Myrsinaceae) is an evergreen, fruiting shrub that has been traditionally used as folklore medicine...
  64. Mu L, Huang C, Zhou W, Guo D, Liu P. Methanolysis of triterpenoid saponin from Ardisia gigantifolia stapf. and structure-activity relationship study against cancer cells. Bioorg Med Chem Lett. 2013;23:6073-8 pubmed publisher
    Thirteen 13,28-epoxy triterpenoid saponins were isolated from Ardisia gigantifolia stapf. and one potential anti-tumor saponin was methanolysised by H2SO4 to afford four new compounds...
  65. Matsui N, Fukuishi N, Fukuyama Y, Yasui Y, Akagi M. Protective effect of the 5-lipoxygenase inhibitor ardisiaquinone A on hepatic ischemia-reperfusion injury in rats. Planta Med. 2005;71:717-20 pubmed
    The protective effects of the 5-lipoxygenase inhibitor ardisiaquinone A, a compound isolated from Ardisia sieboldii, on hepatic ischemia-reperfusion (I/R) injury was studied in rats...
  66. Lou L, Ye W, Chen Y, Wu S, Jin L, He J, et al. Ardipusilloside inhibits survival, invasion and metastasis of human hepatocellular carcinoma cells. Phytomedicine. 2012;19:603-8 pubmed publisher
    Ardipusilloside I is a triterpene-saponin isolated from the Traditional Chinese Medicine Ardisia pusilla A. DC. Its effects and mechanism on invasion and metastasis of liver cancer cells are unclear.
  67. Tuljapurkar S, Horvitz C, Pascarella J. The many growth rates and elasticities of populations in random environments. Am Nat. 2003;162:489-502 pubmed
    ..We argue that a fundamental tool for studying selection pressures in varying environments is the response of growth rate to vital rates in all habitat states...
  68. Qi Z, Yang H. [Herbological study of 4 Chinese herbs in Ardisia and "yiedihong"]. Zhong Yao Cai. 1997;20:257-9 pubmed
    ..The research shows that they are not the same plant with different names. Also, "Yiedihong" doesn't belong to Ardisia.
  69. Qi Z. [Discussions with the author of Materia Medica Textual Research on the original plants of the medicinal herbs in Ardisia (comment)]. Zhong Yao Cai. 1999;22:363-5 pubmed
    ..medicinal herbs given by the Materia Medica Textual Research on the Original Plants of the Medicinal Herbs in Ardisia were raised in this paper...