lonicera

Summary

Summary: A plant genus of the family CAPRIFOLIACEAE. Members contain iridoid glucosides.

Top Publications

  1. Li H, Zhang Z, Li P. [Comparative study on volatile oils in flower and stem of Lonicera japonica]. Zhong Yao Cai. 2002;25:476-7 pubmed
    To study the volatile oils in flower and stem of Lonicera japonica. Thunb.
  2. Wang H, Ross Friedman C, Shi J, Zheng Z. Anatomy of leaf abscission in the Amur honeysuckle (Lonicera maackii, Caprifoliaceae): a scanning electron microscopy study. Protoplasma. 2010;247:111-6 pubmed publisher
    b>Lonicera maackii (Rupr.) Maxim. (Amur honeysuckle) is native to Asia and an important ornamental in China. However, the anatomy of leaf abscission (shedding) in L. maackii had not been studied previously...
  3. Svobodova A, Zdarilova A, Vostalova J. Lonicera caerulea and Vaccinium myrtillus fruit polyphenols protect HaCaT keratinocytes against UVB-induced phototoxic stress and DNA damage. J Dermatol Sci. 2009;56:196-204 pubmed publisher
    ..Topical application of agents with UV absorbing, antioxidant and anti-inflammatory activities is a successful strategy in the protection of the skin against UV-caused damage...
  4. Xiong J, Li S, Wang W, Hong Y, Tang K, Luo Q. Screening and identification of the antibacterial bioactive compounds from Lonicera japonica Thunb. leaves. Food Chem. 2013;138:327-33 pubmed publisher
    Our aim was to screen for antibacterial bioactive compounds from Lonicera japonica leaves. Staphylococcus aureus and Escherichia coli were used as the indicator bacteria...
  5. Leung H, Hour M, Chang W, Wu Y, Lai M, Wang M, et al. P38-associated pathway involvement in apoptosis induced by photodynamic therapy with Lonicera japonica in human lung squamous carcinoma CH27 cells. Food Chem Toxicol. 2008;46:3389-400 pubmed publisher
    Photodynamic therapy (PDT) is an effective therapy for local malignant tumors. Lonicera japonica was found to have the anti-tumor effect...
  6. Li Y, Chen J, Li Y, Li P. Identification and quantification of free radical scavengers in the flower buds of Lonicera species by online HPLC-DPPH assay coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Biomed Chromatogr. 2012;26:449-57 pubmed publisher
    Flos Lonicerae, derived from the flower buds of several medicinal Lonicera species, is a commonly used herbal medicine with multiple pharmacological activities, one of the major ones being antioxidant activity...
  7. Ryu K, Rhee H, Kim J, Yoo H, Lee B, Um K, et al. Anti-inflammatory and analgesic activities of SKLJI, a highly purified and injectable herbal extract of Lonicera japonica. Biosci Biotechnol Biochem. 2010;74:2022-8 pubmed
    ..study, in an effort to develop a safe injectable analgesic phytomedicine, we prepared a tannin and saponin-free Lonicera japonica extract, SKLJI, through fractionation and column purification, and evaluated its anti-inflammatory and ..
  8. Miyashita T, Araki H, Hoshino Y. Ploidy distribution and DNA content variations of Lonicera caerulea (caprifoliaceae) in Japan. J Plant Res. 2011;124:1-9 pubmed publisher
    Ploidy level and geographical distribution were investigated in Japanese Lonicera caerulea L. Flow cytometric analysis revealed the presence of DNA diploid and DNA tetraploid plants in Japan...
  9. Peng X, Li W, Wang W, Bai G. Identification of Lonicera japonica by PCR-RFLP and allele-specific diagnostic PCR based on sequences of internal transcribed spacer regions. Planta Med. 2010;76:497-9 pubmed publisher
    The flower buds of Lonicera japonica Thunb. are widely used in Chinese medicine for their anti-inflammatory prosperities. Some closely related species of L...

More Information

Publications88

  1. Kwon S, Hong S, Kim J, Jung Y, Kim S, Kim H, et al. The neuroprotective effects of Lonicera japonica THUNB. against hydrogen peroxide-induced apoptosis via phosphorylation of MAPKs and PI3K/Akt in SH-SY5Y cells. Food Chem Toxicol. 2011;49:1011-9 pubmed publisher
    We investigated the neuroprotective effects of Lonicera japonica THUNB...
  2. Park J, Bae H, Lee G, Hong B, Yoo H, Lim S, et al. Prophylactic effects of Lonicera japonica extract on dextran sulphate sodium-induced colitis in a mouse model by the inhibition of the Th1/Th17 response. Br J Nutr. 2013;109:283-92 pubmed publisher
    ..Japanese honeysuckle flower, the flower of Lonicera japonica, is a well-known dietary supplement and has been used to prevent or treat various inflammatory diseases...
  3. Jiang C, Yuan Y, Liu G, Huang L, Wang X, Yu J, et al. [EST-SSR identification of Lonicera japonica Thunb]. Yao Xue Xue Bao. 2012;47:803-10 pubmed
    ..b>Lonicera japonica Thunb. is one of Chinese herbal medicines widely demanded. A total of 3 705 EST-SSRs of L...
  4. Lin L, Zhang X, Zhu J, Gao H, Wang Z, Wang W. Two new triterpenoid saponins from the flowers and buds of Lonicera japonica. J Asian Nat Prod Res. 2008;10:925-9 pubmed publisher
    ..triterpenoid saponins, loniceroside D (1) and loniceroside E (2), were isolated from the dry flowers and buds of Lonicera japonica Thunb...
  5. Huh J, Lee W, Seo B, Baek Y, Lee J, Choi D, et al. Gastroprotective and safety effects of WIN-34B, a novel treatment for osteoarthritis, compared to NSAIDs. J Ethnopharmacol. 2011;137:1011-7 pubmed publisher
    The dried flowers of Lonicera japonica, also known as Japanese honeysuckle, and the dried root of Anemarrhena asphodeloides, the component herbs of WIN-34B, are traditionally used in Eastern medicine to treat various inflammatory ..
  6. Wang C, Li P, Ding J, Fishbein A, Yuan C. Discrimination of Lonicera japonica THUNB. from different geographical origins using restriction fragment length polymorphism analysis. Biol Pharm Bull. 2007;30:779-82 pubmed
    b>Lonicera japonica THUNB. is a commonly used anti-inflammatory herbal medicine. The therapeutic effectiveness of L. japonica depends significantly on its geographical origin...
  7. Park H, Park K, Lee D, Kang S, Nagappan A, Kim J, et al. Polyphenolic extract isolated from Korean Lonicera japonica Thunb. induce G2/M cell cycle arrest and apoptosis in HepG2 cells: involvements of PI3K/Akt and MAPKs. Food Chem Toxicol. 2012;50:2407-16 pubmed publisher
    b>Lonicera japonica Thunb. (L. japonica T.) has been used in Korean traditional medicine for long time because of its anti-cancer and hepatic protective effect. In this study, we investigated polyphenolic extract in L. japonica T...
  8. He L, Xu X, Li Y, Li C, Zhu Y, Yan H, et al. Transcriptome analysis of buds and leaves using 454 pyrosequencing to discover genes associated with the biosynthesis of active ingredients in Lonicera japonica Thunb. PLoS ONE. 2013;8:e62922 pubmed publisher
    b>Lonicera japonica Thunb. is a plant used in traditional Chinese medicine known for its anti-inflammatory, anti-oxidative, anti-carcinogenic, and antiviral pharmacological properties...
  9. Chaovanalikit A, Thompson M, Wrolstad R. Characterization and quantification of anthocyanins and polyphenolics in bluehHoneysuckle (Lonicera caerulea L.). J Agric Food Chem. 2004;52:848-52 pubmed
    Anthocyanins and phenolics of 10 blue honeysuckle (Lonicera caerulea L.) genotypes were characterized and quantified by HPLC-DAD. Peak assignments were confirmed by low-resolution electrospray mass spectrometry...
  10. Zhou J, Qian Z, Luo Y, Tang D, Chen H, Yi L, et al. Screening and mechanism study of components targeting DNA from the Chinese herb Lonicera japonica by liquid chromatography/mass spectrometry and fluorescence spectroscopy. Biomed Chromatogr. 2008;22:1164-72 pubmed publisher
    ..for screening bioactive compounds binding to calf thymus deoxyribonucleic acid (ct-DNA) from the extracts of Lonicera japonica...
  11. Sun Z, Gao T, Yao H, Shi L, Zhu Y, Chen S. Identification of Lonicera japonica and its related species using the DNA barcoding method. Planta Med. 2011;77:301-6 pubmed publisher
    ..RBCL, MATK, PSBA-TRNH, ITS2, ITS, TRNL intron, and TRNL-F intergenic spacer) were tested on forty-four samples of LONICERA JAPONICA and its closely related species using the DNA barcoding method...
  12. Tian J, Che H, Ha D, Wei Y, Zheng S. Characterization and anti-allergic effect of a polysaccharide from the flower buds of Lonicera japonica. Carbohydr Polym. 2012;90:1642-7 pubmed publisher
    ..8×10(5) Da, was isolated from the flower buds of Lonicera japonica...
  13. Choi C, Jung H, Kang S, Choi J. Antioxidant constituents and a new triterpenoid glycoside from Flos Lonicerae. Arch Pharm Res. 2007;30:1-7 pubmed
    ..investigations into herb-derived antioxidant agents, we have evaluated the antioxidant effects of Flos Lonicerae (Lonicera japonica flowers), via 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, total reactive oxygen species (ROS), ..
  14. Chien S, Yang C, Tseng Y, Tsay H, Kuo Y, Wang S. Lonicera hypoglauca inhibits xanthine oxidase and reduces serum uric acid in mice. Planta Med. 2009;75:302-6 pubmed publisher
    ..The ability of extracts of Lonicera hypoglauca (Caprifoliaceae) to inhibit XOD was investigated in this study...
  15. Qiu F, Li Z, He L, Wang D. HPLC-ESI-MS/MS analysis and pharmacokinetics of luteoloside, a potential anticarcinogenic component isolated from Lonicera japonica, in beagle dogs. Biomed Chromatogr. 2013;27:311-7 pubmed publisher
    Luteoloside is a potential anticarcinogenic component isolated from Lonicera japonica, a traditional Chinese medicine (TCM)...
  16. Peng X, Li W, Wang W, Bai G. Cloning and characterization of a cDNA coding a hydroxycinnamoyl-CoA quinate hydroxycinnamoyl transferase involved in chlorogenic acid biosynthesis in Lonicera japonica. Planta Med. 2010;76:1921-6 pubmed publisher
    The flower buds of Lonicera japonica are widely used in Chinese medicine for their anti-inflammatory properties. The reason why L...
  17. Thanabhorn S, Jaijoy K, Thamaree S, Ingkaninan K, Panthong A. Acute and subacute toxicity study of the ethanol extract from Lonicera japonica Thunb. J Ethnopharmacol. 2006;107:370-3 pubmed
    The ethanol extract from the leaves of Lonicera japonica Thunb. was evaluated for acute and subacute toxicity...
  18. Kang M, Jung I, Hur J, Kim S, Lee J, Kang J, et al. The analgesic and anti-inflammatory effect of WIN-34B, a new herbal formula for osteoarthritis composed of Lonicera japonica Thunb and Anemarrhena asphodeloides BUNGE in vivo. J Ethnopharmacol. 2010;131:485-96 pubmed publisher
    b>Lonicera japonica Thunb and Anemarrhena asphodeloides BUNGE have been used for the treatment of a variety of inflammatory diseases, cold and infective diseases in many countries, including Korea and China.
  19. Zdarilova A, Rajnochová Svobodová A, Chytilová K, Simanek V, Ulrichova J. Polyphenolic fraction of Lonicera caerulea L. fruits reduces oxidative stress and inflammatory markers induced by lipopolysaccharide in gingival fibroblasts. Food Chem Toxicol. 2010;48:1555-61 pubmed publisher
    ..Berries of Lonicera caerulea L...
  20. Gao W, Yang H, Qi L, Liu E, Ren M, Yan Y, et al. Unbiased metabolite profiling by liquid chromatography-quadrupole time-of-flight mass spectrometry and multivariate data analysis for herbal authentication: classification of seven Lonicera species flower buds. J Chromatogr A. 2012;1245:109-16 pubmed publisher
    ..and unbiased comparative multivariate analysis of the metabolite composition of 33-batch samples covering seven Lonicera species...
  21. Yuan Y, Song L, Li M, Liu G, Chu Y, Ma L, et al. Genetic variation and metabolic pathway intricacy govern the active compound content and quality of the Chinese medicinal plant Lonicera japonica thunb. BMC Genomics. 2012;13:195 pubmed publisher
    ..The herb Flos Lonicerae Japonicae (FLJ or Lonicera japonica Thunb...
  22. Smolik M, Ochmian I, Grajkowski J. Genetic variability of Polish and Russian accessions of cultivated blue honeysuckle (Lonicera caerulea). Genetika. 2010;46:1079-85 pubmed
    ..genome and to evaluate genetic diversity among fourteen Polish and Russian blue honeysuckle accessions (Lonicera caerulea var. edulis, L. caerulea no. 7661, L. caerulea no...
  23. Poulette M, Arthur M. The impact of the invasive shrub Lonicera maackii on the decomposition dynamics of a native plant community. Ecol Appl. 2012;22:412-24 pubmed
    ..We examined the influence of the exotic invasive shrub Lonicera maackii on decomposition dynamics under three native tree species: Fraxinus quadrangulata, Quercus muehlenbergii, ..
  24. Yao X, Gongyu G, Chen G. Determination of active constituents in Lonicera confusa DC. by capillary electrophoresis with amperometric detection. Biomed Chromatogr. 2006;20:1192-9 pubmed
    ..3,5-dicaffeoylquinic acid and caffeic acid in the dried flower buds, leaves and stems (three medicinal parts) of Lonicera confusa DC., respectively...
  25. Jeong J, Ha Y, Jin Y, Lee E, Kim J, Kim H, et al. Rutin from Lonicera japonica inhibits myocardial ischemia/reperfusion-induced apoptosis in vivo and protects H9c2 cells against hydrogen peroxide-mediated injury via ERK1/2 and PI3K/Akt signals in vitro. Food Chem Toxicol. 2009;47:1569-76 pubmed publisher
    We investigated pharmacological effects of rutin isolated form Lonicera japonica on H2O2-induced cell death in H9c2 cells in vitro and rat myocardial ischemia-reperfusion injury model in vivo...
  26. Yoo H, Kang H, Song Y, Park E, Lim C. Anti-angiogenic, antinociceptive and anti-inflammatory activities of Lonicera japonica extract. J Pharm Pharmacol. 2008;60:779-86 pubmed publisher
    This study aimed to elucidate some novel pharmacological activities of Lonicera japonica (Caprifoliaceae), which is widely used in Oriental folk medicine. The ethanolic extract of L...
  27. Teng Y, Sun C, Li G, Sun G, Nomachi Y, Yokota J, et al. Protective effects of Flos lonicera extract on acute liver injury by dimethylnitrosamine-induced in rats. J Nat Med. 2010;64:288-94 pubmed publisher
    The aim of this study is to investigate effects of Flos lonicera extract (FLE) on acute liver injury model rats which induced by 35 mg/kg dimethylnitrosamine (DMN)...
  28. Kang O, Choi J, Lee J, Kwon D. Luteolin isolated from the flowers of Lonicera japonica suppresses inflammatory mediator release by blocking NF-kappaB and MAPKs activation pathways in HMC-1 cells. Molecules. 2010;15:385-98 pubmed publisher
    ..In the present study, the effect of luteolin from the flowers of Lonicera japonica on phorbol 12-myristate 13-acetate (PMA) plus A23187-induced mast cell activation was examined...
  29. Shang X, Pan H, Li M, Miao X, Ding H. Lonicera japonica Thunb.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine. J Ethnopharmacol. 2011;138:1-21 pubmed publisher
    b>Lonicera japonica Thunb. (Caprifoliaceae), a widely used traditional Chinese medicine, was known as Jin Yin Hua (Chinese: ), Ren Dong and Japanese honeysuckle...
  30. Jin X, Ohgami K, Shiratori K, Suzuki Y, Koyama Y, Yoshida K, et al. Effects of blue honeysuckle (Lonicera caerulea L.) extract on lipopolysaccharide-induced inflammation in vitro and in vivo. Exp Eye Res. 2006;82:860-7 pubmed
    ..These results suggest that BHE attenuates the degree of inflammation in eyes with EIU by inhibiting the NF-kappaB dependent signaling pathway and the subsequent production of proinflammatory mediators...
  31. Liu Z, He X, Chen W, Yuan F, Yan K, Tao D. Accumulation and tolerance characteristics of cadmium in a potential hyperaccumulator--Lonicera japonica Thunb. J Hazard Mater. 2009;169:170-5 pubmed publisher
    ..In the study, growth responses, cadmium (Cd) accumulation capability and physiological mechanisms of Lonicera japonica Thunb. under Cd stress were investigated...
  32. Qian Z, Li H, Li P, Chen J, Tang D. Simultaneous quantification of seven bioactive components in Caulis Lonicerae Japonicae by high performance liquid chromatography. Biomed Chromatogr. 2007;21:649-54 pubmed
    ..in Caulis Lonicerae Japonicae, a commonly used traditional Chinese medicinal herb derived from the caulis of Lonicera japonica Thunb...
  33. Lan W, Zhaojun Z, Zesheng Z. Characterization of antioxidant activity of extracts from Flos Lonicerae. Drug Dev Ind Pharm. 2007;33:841-7 pubmed
  34. El Sayed A, Mitchell V, McLaren G, Manning L, Bunn B, Suckling D. Attraction of New Zealand flower thrips, Thrips obscuratus, to cis-jasmone, a volatile identified from Japanese honeysuckle flowers. J Chem Ecol. 2009;35:656-63 pubmed publisher
    This work was undertaken to identify floral compound(s) produced by honeysuckle flowers, Lonicera japonica (Thunberg), that mediate the attraction of New Zealand flower thrips Thrips obscuratus (Crawford)...
  35. Oku H, Ogawa Y, Iwaoka E, Ishiguro K. Allergy-preventive effects of chlorogenic acid and iridoid derivatives from flower buds of Lonicera japonica. Biol Pharm Bull. 2011;34:1330-3 pubmed
    Allergy-preventive activity of flower buds of Lonicera japonica THUNB...
  36. Wang S, Tseng C, Tsai K, Lin C, Wen C, Tsay H, et al. Bioactivity-guided screening identifies pheophytin a as a potent anti-hepatitis C virus compound from Lonicera hypoglauca Miq. Biochem Biophys Res Commun. 2009;385:230-5 pubmed publisher
    ..In this study, we performed bioactivity-guided screening of the Lonicera hypoglauca Miq. crude extracts to find for naturally chemical entities with anti-HCV activity...
  37. Wang J, Zhao X, Qi Q, Tao L, Zhao Q, Mu R, et al. Macranthoside B, a hederagenin saponin extracted from Lonicera macranthoides and its anti-tumor activities in vitro and in vivo. Food Chem Toxicol. 2009;47:1716-21 pubmed publisher
    Macranthoside B (MB) is a hederagenin saponin extracted from the flower bud of Lonicera macranthoides...
  38. Tang D, Li H, Chen J, Guo C, Li P. Rapid and simple method for screening of natural antioxidants from Chinese herb Flos Lonicerae Japonicae by DPPH-HPLC-DAD-TOF/MS. J Sep Sci. 2008;31:3519-26 pubmed publisher
    ..and identification of natural antioxidants of Flos Lonicerae Japonicae (FLJ), derived from the flower buds of Lonicera japonica...
  39. Cipollini D, Stevenson R, Enright S, Eyles A, Bonello P. Phenolic metabolites in leaves of the invasive shrub, Lonicera maackii, and their potential phytotoxic and anti-herbivore effects. J Chem Ecol. 2008;34:144-52 pubmed publisher
    b>Lonicera maackii is an invasive shrub in North America for which allelopathic effects toward other plants or herbivores have been suspected. We characterized the major phenolic metabolites present in methanol extracts of L. maackii leaves...
  40. Xu Y, Oliverson B, Simmons D. Trifunctional inhibition of COX-2 by extracts of Lonicera japonica: direct inhibition, transcriptional and post-transcriptional down regulation. J Ethnopharmacol. 2007;111:667-70 pubmed
    The anti-inflammatory properties of aqueous extracts from Lonicera japonica (LJ) flower, an anti-inflammatory treatment in traditional Chinese medicine, were tested by radioimmunoassay of cyclooxygenase isoenzyme-generated prostaglandin ..
  41. Chai X, Li S, Li P. Quality evaluation of Flos lonicerae through a simultaneous determination of seven saponins by HPLC with ELSD. J Chromatogr A. 2005;1070:43-8 pubmed
    ..0% and 6.0%, respectively. The validated method was successfully applied to quantify seven saponins in five sources of Flos Lonicerae, which provides a new basis of overall assessment on quality of Flos Lonicerae...
  42. Kwak W, Han C, Chang H, Kim H, Kang S, Son K. Loniceroside C, an antiinflammatory saponin from Lonicera japonica. Chem Pharm Bull (Tokyo). 2003;51:333-5 pubmed
    A new triterpenoid saponin, loniceroside C was isolated from the aerial parts of Lonicera japonica...
  43. Chen C, Peng W, Wu L, Wu C, Hsu S. Luteolin ameliorates experimental lung fibrosis both in vivo and in vitro: implications for therapy of lung fibrosis. J Agric Food Chem. 2010;58:11653-61 pubmed publisher
    b>Lonicera japonica (Caprifoliaceae) has been known as an anti-inflammatory herb in traditional Chinese medicine for thousands of years and is used constantly for upper respiratory tract infections...
  44. Smith S, Donoghue M. Combining historical biogeography with niche modeling in the Caprifolium clade of Lonicera (Caprifoliaceae, Dipsacales). Syst Biol. 2010;59:322-41 pubmed publisher
    The Lonicera clade Caprifolium contains approximately 25 species distributed around the Northern Hemisphere, including in the Mediterranean climates of California and Europe...
  45. Allan B, Dutra H, Goessling L, Barnett K, Chase J, Marquis R, et al. Invasive honeysuckle eradication reduces tick-borne disease risk by altering host dynamics. Proc Natl Acad Sci U S A. 2010;107:18523-7 pubmed publisher
    ..Here we demonstrate that a widespread invasive shrub in North America, Amur honeysuckle (Lonicera maackii), increases human risk of exposure to ehrlichiosis, an emerging infectious disease caused by bacterial ..
  46. Wu S, Yano S, Chen J, Hisanaga A, Sakao K, He X, et al. Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-Induced Inflammation through Dual Modulation of Inflammatory and Antioxidant Mediators. J Agric Food Chem. 2017;65:5133-5141 pubmed publisher
    b>Lonicera caerulea L. berry polyphenols (LCBP) are considered as major components for bioactivity...
  47. Huang L, Xiong X, Zhong Y, Cen M, Cheng X, Wang G, et al. Pharmacokinetics of isochlorgenic acid C in rats by HPLC-MS: Absolute bioavailability and dose proportionality. J Ethnopharmacol. 2016;185:105-9 pubmed publisher
    Isochlorgenic acid C (IAC), one of the bioactive compounds of Lonicera japonica, exhibited diverse pharmacological effects. However, its pharmacokinetic properties and bioavailability remained unresolved...
  48. Hong S, Kwon J, Shin J, Kim J, Minai Tehrani A, Yu K, et al. Therapeutic effect of Broussonetia papyrifera and Lonicera japonica in ovalbumin-induced murine asthma model. Nat Prod Commun. 2013;8:1609-14 pubmed
    Broussonetia papyrifera (L.) Vent. and Lonicera japonica Thunb. have been used in recent medicinal research for their antioxidative and anti-inflammatory properties. The present study investigated the therapeutic efficacy of B...
  49. Nikzad Langerodi R, Ortmann S, Pferschy Wenzig E, Bochkov V, Zhao Y, Miao J, et al. Assessment of anti-inflammatory properties of extracts from Honeysuckle (Lonicera sp. L., Caprifoliaceae) by ATR-FTIR spectroscopy. Talanta. 2017;175:264-272 pubmed publisher
    ..assess different anti-inflammatory properties of ethanolic extracts from various species of the Genus Lonicera (Caprifoliaceae)...
  50. Zhu W, Zheng W, Hu X, Xu X, Zhang L, Tian J. Variations of metabolites and proteome in Lonicera japonica Thunb. buds and flowers under UV radiation. Biochim Biophys Acta Proteins Proteom. 2017;1865:404-413 pubmed publisher
    b>Lonicera japonica Thunb., also known as Jin Yin Hua and Japanese honeysuckle, is used as a herbal medicine in Asian countries...
  51. Li N, You X, Peng J, Wang J. [Comparative study on yield and quality of flower buds of Lonicera japonica within several flowering stages]. Zhongguo Zhong Yao Za Zhi. 2009;34:1346-50 pubmed
    ..The samples of the two-site white flower and the whole-white flower had the higher comprehensive quality. The components of vitamine E and the steroids in the volatile oil need to be paid more attention. ..
  52. Lee Y, Yeh S, Ruan X, Zhang H, Hsu S, Huang H, et al. Honeysuckle aqueous extract and induced let-7a suppress dengue virus type 2 replication and pathogenesis. J Ethnopharmacol. 2017;198:109-121 pubmed publisher
    Honeysuckle (Lonicera japonica Thunb.), a traditional Chinese herb, has widely been used to treat pathogen infection. However, the underlying-mechanism remains elusive...
  53. Ijaz F, Iqbal Z, Rahman I, Alam J, Khan S, Shah G, et al. Investigation of traditional medicinal floral knowledge of Sarban Hills, Abbottabad, KP, Pakistan. J Ethnopharmacol. 2016;179:208-33 pubmed publisher
    ..81). The medicinal plant species with maximum fidelity level were Ziziphus jujuba (100%) and Lonicera caprifolium (92.31%) whereas the medicinal with most relative frequency citation were B. lycium (0...
  54. Zhao X, Wang D, Qin L, Yang X, Gao C. Comparative investigation for hypoglycemic effects of polysaccharides from four substitutes of Lonicera japonica in Chinese medicine. Int J Biol Macromol. 2018;109:12-20 pubmed publisher
    The polysaccharide fractions were obtained from flower buds of the four substitutes of Lonicera japonica, L. macranthoides (LMPB), L. hypoglauca (LHPB), L. fulvotomentosa (LFPB) and L...
  55. Xu S, Fu W, He X, Chen W, Zhang W, Li B, et al. Drought Alleviated the Negative Effects of Elevated O3 on Lonicera maackii in Urban Area. Bull Environ Contam Toxicol. 2017;99:648-653 pubmed publisher
    ..chambers were used to study the changes in photosynthesis, physiology and stomata characteristics in 1-year-old Lonicera maackii seedlings exposed to drought (DT, 30%-35% soil saturated water content) or/and elevated ozone (EO, 80 ..
  56. Niu X, Cui X, Su H, Guo Y, Dong X. [Simultaneous determination of seven compounds in Lonicera japonica by high performance liquid chromatography]. Se Pu. 2012;30:211-4 pubmed
    ..performance liquid chromatographic (HPLC) method was developed to determine the contents of seven compounds in Lonicera japonica and Folium Lonicerae with maximum wavelength conversion program, and analyze the content differences ..
  57. Mahboob T, Azlan A, Tan T, Samudi C, Sekaran S, Nissapatorn V, et al. Anti-encystment and amoebicidal activity of Lonicera japonica Thunb. and its major constituent chlorogenic acid in vitro. Asian Pac J Trop Med. 2016;9:866-871 pubmed publisher
    To examine the acanthamoebicidal effects of ethyl acetate, aqueous and butanol fractions of dried flower buds of Lonicera japonica (L. japonica) Thunb. (Flos Lonicerae) in vitro...
  58. Wang F, Jiang Y, Wang X, Lin S, Pu P, Zhu C, et al. [Chemical constituents from flower buds of Lonicera japonica]. Zhongguo Zhong Yao Za Zhi. 2013;38:1378-85 pubmed
    ..These compounds were obtained from this plant for the first time. ..
  59. Jiang N. [Study on Chemical Constituents of Lonicera japonica Bud]. Zhong Yao Cai. 2015;38:315-7 pubmed
    To study the chemical constituents of Lonicera japonica bud. The compounds were isolated and repeatedly purified by silica gel column chromatography, gel column chromatography and ODS chromatography...
  60. Lee J, Han Y. Antiarthritic effect of lonicerin on Candida albicans arthritis in mice. Arch Pharm Res. 2011;34:853-9 pubmed publisher
    ..01). These data suggest that lonicerin alone, which has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection. ..
  61. Du H, Zhang Y, Liu H, Su J, Wei Y, Ma B, et al. Allonocardiopsis opalescens gen. nov., sp. nov., a new member of the suborder Streptosporangineae, from the surface-sterilized fruit of a medicinal plant. Int J Syst Evol Microbiol. 2013;63:900-4 pubmed publisher
    An endophytic actinomycete, designated strain I10A-01259(T), was isolated from a surface-sterilized fruit of Lonicera maackii (Rupr.) Maxim., a medicinal plant, which was collected from a suburb of Beijing, China...
  62. Xin N, Feng J, Huang L, Yin S. [Study on fingerprint spectrum of Lonicera macranthoides by HPLC]. Zhong Yao Cai. 2008;31:1138-42 pubmed
    To establish the fingerprint spectrum of Lonicera macranthoides by HPLC. The column of Hypersil gold C18 (4. 6 mm x 250 mm, 5 microm) was used. The mobile phase consisted of Acetonitril-0.05% phosphoric acid with gradient elution...
  63. Kwon S, Hong S, Jung Y, Kim M, Kim S, Kim H, et al. Lonicera japonica THUNB. protects 6-hydroxydopamine-induced neurotoxicity by inhibiting activation of MAPKs, PI3K/Akt, and NF-?B in SH-SY5Y cells. Food Chem Toxicol. 2012;50:797-807 pubmed publisher
    In this study, we investigated the neuroprotective effects of Lonicera japonica THUNB. extract (LJ) on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity in SH-SY5Y cells...
  64. Kuebbing S, Patterson C, Classen A, Simberloff D. Co-occurring nonnative woody shrubs have additive and non-additive soil legacies. Ecol Appl. 2016;26:1896-1906 pubmed publisher
    ..feedback experiment to test for non-additive soil impacts of two common invasive nonnative woody shrubs, Lonicera maackii and Ligustrum sinense, in deciduous forests of the southeastern United States...
  65. Feng C, Su S, Wang L, Wu J, Tang Z, Xu Y, et al. Antioxidant capacities and anthocyanin characteristics of the black-red wild berries obtained in Northeast China. Food Chem. 2016;204:150-8 pubmed publisher
    ..The compositions and contents of anthocyanins in black (Padus maackii, Padus avium, Lonicera caerulea, and Ribes nigrum) and red (Ribes rubrum, Sambucus williamsii, Rubus idaeus, and Ribes procumbens) wild ..
  66. Xu Y, Zhang J, Jiang Q, Zhou L, Miao H. [Effects of water stress on the growth of Lonicera japonica and quality of honeysuckle]. Zhong Yao Cai. 2006;29:420-3 pubmed
    Effects of water stress on the growth of Lonicera japonica and quality of honeysuckle were studied...
  67. Ziyan L, Yongmei Z, Nan Z, Ning T, Baolin L. Evaluation of the anti-inflammatory activity of luteolin in experimental animal models. Planta Med. 2007;73:221-6 pubmed
  68. Lu Y, Dong G, Gu Y, Ito Y, Wei Y. Separation of chlorogenic acid and concentration of trace caffeic acid from natural products by pH-zone-refining countercurrent chromatography. J Sep Sci. 2013;36:2210-5 pubmed publisher
    ..3 g of crude extract of Lonicerae Flos have been obtained. These results suggest that pH-zone-refining CCC is suitable for the isolation of the chlorogenic acid from the crude extracts of F. bidentis and Lonicerae Flos. ..
  69. Liu N, Liu W, Feng J, Zhou Y, Liu J, Wang X, et al. [Dynamic changes of enzyme activities and active component contents in Lonicera japonica during different blossoming stages]. Zhongguo Zhong Yao Za Zhi. 2013;38:1905-9 pubmed
    This paper aimed to study the dynamic changes of enzyme activities and active component contents in Lonicera japonica during different blossoming stages...
  70. Vostalova J, Galandáková A, Palikova I, Ulrichova J, Doležal D, Lichnovská R, et al. Lonicera caerulea fruits reduce UVA-induced damage in hairless mice. J Photochem Photobiol B. 2013;128:1-11 pubmed publisher
    ..We investigated the effect of consuming Lonicera caerulea berries on UVA-induced damage in SKH-1 mice. The mice were fed a diet containing L...
  71. Schwarz D, Shoemaker K, Botteri N, McPheron B. A novel preference for an invasive plant as a mechanism for animal hybrid speciation. Evolution. 2007;61:245-56 pubmed
    ..One example of a host-specific parasite is the Lonicera fly, a population of tephritid fruit flies that evolved within the last 250 years likely by hybridization between ..
  72. Jurikova T, Sochor J, Rop O, Mlcek J, Balla S, Szekeres L, et al. Evaluation of polyphenolic profile and nutritional value of non-traditional fruit species in the Czech Republic--a comparative study. Molecules. 2012;17:8968-81 pubmed publisher
    ..polyphenolic profile of a number of non-traditional fruit species and their genotypes, namely blue honeysuckle (Lonicera spp...
  73. Watling J, Hickman C, Lee E, Wang K, Orrock J. Extracts of the invasive shrub Lonicera maackii increase mortality and alter behavior of amphibian larvae. Oecologia. 2011;165:153-9 pubmed publisher
    ..Larvae were reared in extracts of the widespread invasive Amur honeysuckle (Lonicera maackii), mixed native leaf litter, and a water control. Anaxyrus americanus tadpoles reared in L...
  74. Guo Q, Zhou F, Wu Q, Zhao W, Zhang Y. [Comparative study on morphological character of leaves of various farm cultivars of Lonicera japonica]. Zhongguo Zhong Yao Za Zhi. 2011;36:1927-30 pubmed
    To provide theoretical evidence for dividing and breeding cultivars of Lonicera japonica, the botanical character of laminas leaves observed and compared.
  75. Zhou W, Cai B, Shan J, Wang S, Di L. Discovery and Current Status of Evaluation System of Bioavailability and Related Pharmaceutical Technologies for Traditional Chinese Medicines--Flos Lonicerae Japonicae--Fructus Forsythiae Herb Couples as an Example. Int J Mol Sci. 2015;16:28812-40 pubmed publisher
    ..We expect that the current study will be positive and informative. ..
  76. Cheng B, Yu H, Guo H, Su T, Fu X, Li T, et al. A herbal formula comprising Rosae Multiflorae Fructus and Lonicerae Japonicae Flos, attenuates collagen-induced arthritis and inhibits TLR4 signalling in rats. Sci Rep. 2016;6:20042 pubmed publisher
    ..In conclusion, RL at nontoxic doses inhibited TLR4 signaling and potently improved clinical conditions of CIA rats. These findings provide further pharmacological justifications for the traditional use of RL in RA management. ..
  77. Fontán N, Alvarez R, de Lera A. Stereoselective synthesis by olefin metathesis and characterization of ?-carotene (7,8,7',8'-tetrahydro-?,?-carotene). J Nat Prod. 2012;75:975-9 pubmed publisher
    ..carotene (7,8,7',8'-tetrahydro-?,?-carotene), a natural C(40) carotenoid first detected in the berries of Lonicera japonica and in citrus fruits sixty years ago, has been synthesized by olefin cross-metathesis/dimerization of a ..
  78. Zhang H, Song J, Shi J. [Screen anti-influenza virus serum marker of Lonicera japonica by proteomics technology]. Zhongguo Zhong Yao Za Zhi. 2011;36:1071-4 pubmed
    The candidate anti-influenza virus serum marker of Lonicera japonica was searched by comparing the serum protein discrepancy of experimental groups...
  79. Chen X, Lin H, Jiang S, Wu K, Liu Y, Tian L, et al. Dietary supplementation of honeysuckle improves the growth, survival and immunity of Penaeus monodon. Fish Shellfish Immunol. 2013;35:161-9 pubmed publisher
    ..Considering the effect of honeysuckle on both growth performance and survival of P. monodon, the level of honeysuckle supplemented in the diet should be between 0.2% and 0.4%...