solanum nigrum

Summary

Summary: A plant species of the genus SOLANUM, family SOLANACEAE that contains steroidal glycosides.

Top Publications

  1. Lee S, Oh P, Ko J, Lim K, Lim K. A 150-kDa glycoprotein isolated from Solanum nigrum L. has cytotoxic and apoptotic effects by inhibiting the effects of protein kinase C alpha, nuclear factor-kappa B and inducible nitric oxide in HCT-116 cells. Cancer Chemother Pharmacol. 2004;54:562-72 pubmed
    This study was carried out to investigate the anticancer effects of a 150-kDa glycoprotein isolated from Solanum nigrum L. (SNL glycoprotein) on spontaneously and experimentally induced tumor promotion in HCT-116 cells...
  2. Zimnoch Guzowska E, Lebecka R, Kryszczuk A, Maciejewska U, Szczerbakowa A, Wielgat B. Resistance to Phytophthora infestans in somatic hybrids of Solanum nigrum L. and diploid potato. Theor Appl Genet. 2003;107:43-8 pubmed
    ..nigrum, while six clones expressed a resistance to P. infestans similar to that of S. nigrum. The results confirm the effective transfer of late blight resistance of S. nigrum into its somatic hybrids with potato...
  3. Heo K, Lim K. Glycoprotein isolated from Solanum nigrum L. modulates the apoptotic-related signals in 12-O-tetradecanoylphorbol 13-acetate-stimulated MCF-7 cells. J Med Food. 2005;8:69-77 pubmed
    b>Solanum nigrum L. (SNL) has been used in folk medicine for its anti-inflammatory activity. We isolated only the SNL glycoprotein from SNL and found that it was cytotoxic at low concentration...
  4. Ahmed A, Rifaat M. Effects of Solanum nigrum leaves water extract on the penetration and infectivity of Schistosoma mansoni cercariae. J Egypt Soc Parasitol. 2005;35:33-40 pubmed
    A crude water extract of Solanum nigrum leaves was used as a chemical attenuate to Schistosoma mansoni cercariae prior to infection of Swiss female mice. Cercariae were exposed to 2.5, 5, 7...
  5. Jainu M, Devi C. Antiulcerogenic and ulcer healing effects of Solanum nigrum (L.) on experimental ulcer models: possible mechanism for the inhibition of acid formation. J Ethnopharmacol. 2006;104:156-63 pubmed
    b>Solanum nigrum, an herbal plant which is recommended in ayurveda for the management of gastric ulcers...
  6. Javed T, Ashfaq U, Riaz S, Rehman S, Riazuddin S. In-vitro antiviral activity of Solanum nigrum against Hepatitis C Virus. Virol J. 2011;8:26 pubmed publisher
    ..Hence, there is a need for the development of more effective, less toxic antiviral agents...
  7. Li J, Li Q, Feng T, Zhang T, Li K, Zhao R, et al. Antitumor activity of crude polysaccharides isolated from Solanum nigrum Linne on U14 cervical carcinoma bearing mice. Phytother Res. 2007;21:832-40 pubmed
    b>Solanum nigrum Linne (SNL) has been used in traditional Chinese medicine for centuries because of its diuretic and antipyretic effects...
  8. Wang H, Chung P, Wu C, Lan K, Yang M, Wang C. Solanum nigrum L. polyphenolic extract inhibits hepatocarcinoma cell growth by inducing G2/M phase arrest and apoptosis. J Sci Food Agric. 2011;91:178-85 pubmed publisher
    ..To search for an effective agent against HCC progression, we prepared a polyphenolic extract of Solanum nigrum L...
  9. Hartl M, Giri A, Kaur H, Baldwin I. Serine protease inhibitors specifically defend Solanum nigrum against generalist herbivores but do not influence plant growth and development. Plant Cell. 2010;22:4158-75 pubmed publisher
    ..We examine Solanum nigrum's SPI profile, comprising four different active inhibitors, of which the most abundant proved to be novel, to ..

More Information

Publications64

  1. Jeong J, Jeong H, Park J, Lee S, Lee J, Lee H, et al. Cancer-preventive peptide lunasin from Solanum nigrum L. inhibits acetylation of core histones H3 and H4 and phosphorylation of retinoblastoma protein (Rb). J Agric Food Chem. 2007;55:10707-13 pubmed
    ..herbal medicines and in search for new sources of lunasin, we report here the properties of lunasin from Solanum nigrum L. (SNL), a plant indigenous to northeast Asia...
  2. Schmidt D, Kessler A, Kessler D, Schmidt S, Lim M, Gase K, et al. Solanum nigrum: a model ecological expression system and its tools. Mol Ecol. 2004;13:981-95 pubmed
    ..Here, we present Solanum nigrum L...
  3. Rezek J, Macek T, Doubsky J, Mackova M. Metabolites of 2,2'-dichlorobiphenyl and 2,6-dichlorobiphenyl in hairy root culture of black nightshade Solanum nigrum SNC-9O. Chemosphere. 2012;89:383-8 pubmed publisher
    The hairy root culture of black nightshade (Solanum nigrum) SNC-9O was exposed to 2,2'-dichlorobiphenyl (PCB 4) and 2,6-dichlorobiphenyl (PCB 10) to follow the metabolites produced...
  4. Rawani A, Ghosh A, Chandra G. Mosquito larvicidal activities of Solanum nigrum L. leaf extract against Culex quinquefasciatus Say. Parasitol Res. 2010;107:1235-40 pubmed publisher
    The present study was carried out to establish the larvicidal activities of crude and solvent extracts of Solanum nigrum L. leaves against Culex quinquefasciatus Say as target species. The results indicated that the mortality rates at 0...
  5. VanDoorn A, Bonaventure G, Schmidt D, Baldwin I. Regulation of jasmonate metabolism and activation of systemic signaling in Solanum nigrum: COI1 and JAR4 play overlapping yet distinct roles. New Phytol. 2011;190:640-52 pubmed publisher
    ..However, their signaling properties, accumulation and metabolism vary substantially among species. Solanum nigrum is a wild Solanaceous species developed as a model to study defense responses...
  6. Jimoh F, Adedapo A, Afolayan A. Comparison of the nutritional value and biological activities of the acetone, methanol and water extracts of the leaves of Solanum nigrum and Leonotis leonorus. Food Chem Toxicol. 2010;48:964-71 pubmed publisher
    ..antioxidant and antibacterial activities of the acetone, methanol and water extracts of the leaves of Solanum nigrum and Leonotis leonorus were investigated using standard analytical methods in order to assess the numerous ..
  7. Wang W, Lu D. [An in vitro study of cytotoxic and antineoplastic effect of Solanum nigrum L extract on U266]. Beijing Da Xue Xue Bao Yi Xue Ban. 2005;37:240-4 pubmed
    To study cytotoxicity and antineoplastic effect in vitro Solanum nigrum L extract on U266.
  8. Li J, Li Q, Peng Y, Zhao R, Han Z, Gao D. Protective effects of fraction 1a of polysaccharides isolated from Solanum nigrum Linne on thymus in tumor-bearing mice. J Ethnopharmacol. 2010;129:350-6 pubmed publisher
    To further screen out the anti-tumor active compound of polysaccharides isolated from Solanum nigrum Linne (SNL-P), which had shown to have anti-cervical cancer and modulating properties, and evaluate the thymus protective effects of this ..
  9. Wan Y, Luo S, Chen J, Xiao X, Chen L, Zeng G, et al. Effect of endophyte-infection on growth parameters and Cd-induced phytotoxicity of Cd-hyperaccumulator Solanum nigrum L. Chemosphere. 2012;89:743-50 pubmed publisher
    ..Seeds of Solanum nigrum L. were inoculated with endophyte Serratia nematodiphila LRE07 and were subjected to Cd in the growing medium...
  10. Raju K, Anbuganapathi G, Gokulakrishnan V, Rajkapoor B, Jayakar B, Manian S. Effect of dried fruits of Solanum nigrum LINN against CCl4-induced hepatic damage in rats. Biol Pharm Bull. 2003;26:1618-9 pubmed
    Ethanol extract of Solanum nigrum LINN was investigated for its hepatoprotective activity against CCl4-induced hepatic damage in rats. The ethanol extract showed remarkable hepatoprotective activity...
  11. Xu J, Yin H, Li X. Protective effects of proline against cadmium toxicity in micropropagated hyperaccumulator, Solanum nigrum L. Plant Cell Rep. 2009;28:325-33 pubmed publisher
    b>Solanum nigrum is a newly discovered Cd-hyperaccumulator. In the present study, the protective effects of proline against cadmium toxicity of callus and regenerated shoots of S...
  12. Wang L, Zhou Q, Ding L, Sun Y. Effect of cadmium toxicity on nitrogen metabolism in leaves of Solanum nigrum L. as a newly found cadmium hyperaccumulator. J Hazard Mater. 2008;154:818-25 pubmed
    ..of N forms and the activity of key enzymes involved in N metabolism in leaves of the Cd hyperaccumulator, Solanum nigrum L...
  13. Lin H, Tseng H, Wang C, Lin J, Lo C, Chou F. Hepatoprotective effects of Solanum nigrum Linn extract against CCl(4)-induced oxidative damage in rats. Chem Biol Interact. 2008;171:283-93 pubmed
    b>Solanum nigrum L. (SN) is an herbal plant that has been used as hepatoprotective and anti-inflammation agent in Chinese medicine...
  14. Luo S, Wan Y, Xiao X, Guo H, Chen L, Xi Q, et al. Isolation and characterization of endophytic bacterium LRE07 from cadmium hyperaccumulator Solanum nigrum L. and its potential for remediation. Appl Microbiol Biotechnol. 2011;89:1637-44 pubmed publisher
    ..In this study, endophytic bacterium LRE07 was isolated from cadmium hyperaccumulator Solanum nigrum L. It was identified as Serratia sp. by 16S rRNA sequence analysis...
  15. Yang M, Hsu L, Peng C, Shi Y, Wu C, Wang C. Polyphenol-rich extracts from Solanum nigrum attenuated PKC alpha-mediated migration and invasion of hepatocellular carcinoma cells. J Agric Food Chem. 2010;58:5806-14 pubmed publisher
    b>Solanum nigrum L. (SN) has exhibited multiple biological effects such as anti-inflammation and antiproliferation. Protein kinase C (PKC) regulates cellular functions including proliferation, migration, and invasion...
  16. Lin H, Tseng H, Wang C, Chyau C, Liao K, Peng P, et al. Induction of autophagy and apoptosis by the extract of Solanum nigrum Linn in HepG2 cells. J Agric Food Chem. 2007;55:3620-8 pubmed
    b>Solanum nigrum L. (SN) has been used in traditional folk medicine to treat different cancers. It is also used as a hepatoprotective and anti-inflammatory agent...
  17. Ahmed A, Rifaat M. Molluscicidal and cercaricidal efficacy of Acanthus mollis and its binary and tertiary combinations with Solanum nigrum and Iris pseudacorus against Biomphalaria alexandrina. J Egypt Soc Parasitol. 2004;34:1041-50 pubmed
    ..Its petroleum ether extract (LC50 values = 6.92 mg/L) was more potent than Solanum nigrum and Iris pseudacorus extracts. A binary combination (1:1) of A. mollis and S...
  18. Hammami H, Ayadi A. Molluscicidal and antiparasitic activity of Solanum nigrum villosum against Galba truncatula infected or uninfected with Fasciola hepatica. J Helminthol. 2008;82:235-9 pubmed publisher
    The present study was based on assessments of the molluscicidal and antiparasitic activities of Solanum nigrum villosum. This plant has been collected in Tozeur's traditional oases (south-western Tunisia)...
  19. Xu Y, Pan R, Chang Q, Qin M, Liu Y, Tang J. [Experimental study of Solanum nigrum on inhibiting angiogenesis in chick chorioallantoic membrane]. Zhongguo Zhong Yao Za Zhi. 2008;33:549-52 pubmed
    To study the inhibitory effect of Solanum nigrum on angiogenesis.
  20. Li J, Li Q, Feng T, Li K. Aqueous extract of Solanum nigrum inhibit growth of cervical carcinoma (U14) via modulating immune response of tumor bearing mice and inducing apoptosis of tumor cells. Fitoterapia. 2008;79:548-56 pubmed publisher
    To explore the antitumor activity of aqueous extract of Solanum nigrum (SNL-AE) and its possible mechanism, we examined the effects of SNL-AE on the tumor growth in vivo, the number of CD4+, CD8+ T lymphocyte subsets of peripheral blood ..
  21. Xu J, Sun J, Du L, Liu X. Comparative transcriptome analysis of cadmium responses in Solanum nigrum and Solanum torvum. New Phytol. 2012;196:110-24 pubmed publisher
    b>Solanum nigrum is a cadmium (Cd) accumulator, whereas Solanum torvum is a low Cd-accumulating plant...
  22. Son Y, Kim J, Lim J, Chung Y, Chung G, Lee J. Ripe fruit of Solanum nigrum L. inhibits cell growth and induces apoptosis in MCF-7 cells. Food Chem Toxicol. 2003;41:1421-8 pubmed
    b>Solanum nigrum L. (SNL) has been traditionally used as a herbal plant, whose fruit is believed to have anti-tumor properties, although the mechanism for the activity remains to be elucidated...
  23. Wang H, Wu D, Chang Y, Li Y, Wang C. Solanum nigrum Linn. water extract inhibits metastasis in mouse melanoma cells in vitro and in vivo. J Agric Food Chem. 2010;58:11913-23 pubmed publisher
    ..Thus, new treatment strategies are urgently needed. Solanum nigrum Linn., commonly used in Oriental medicine, has showed antineoplastic activity in human cancer cell lines...
  24. Zakaria Z, Sulaiman M, Morsid N, Aris A, Zainal H, Pojan N, et al. Antinociceptive, anti-inflammatory and antipyretic effects of Solanum nigrum aqueous extract in animal models. Methods Find Exp Clin Pharmacol. 2009;31:81-8 pubmed publisher
    ..out to evaluate the antinociceptive, anti-inflammatory and antipyretic effects of the aqueous extract of Solanum nigrum leaves using various animal models...
  25. Raghavendra K, Singh S, Subbarao S, Dash A. Laboratory studies on mosquito larvicidal efficacy of aqueous & hexane extracts of dried fruit of Solanum nigrum Linn. Indian J Med Res. 2009;130:74-7 pubmed
    ..Comparative efficacy of the aqueous and hexane extracts of dried fruit of Solanum nigrum was tested against five laboratory colonized strains of mosquito species, namely Anopheles culicifacies ..
  26. Poczai P, Hyvönen J. On the origin of Solanum nigrum: can networks help?. Mol Biol Rep. 2011;38:1171-85 pubmed publisher
    ..Solanum, which have possibly taken part in the formation of Solanum nigrum, utilizing multi-locus (SCoT, ISSR) markers combined with chloroplast trnL-F sequence data and morphological ..
  27. Rezek J, Macek T, Mackova M, Triska J. Plant metabolites of polychlorinated biphenyls in hairy root culture of black nightshade Solanum nigrum SNC-9O. Chemosphere. 2007;69:1221-7 pubmed
    ..trichlorinated, five tetrachlorinated and one pentachlorinated PCB congener transformed by black nightshade (Solanum nigrum) hairy root culture SNC-9O...
  28. Zhou X, He X, Wang G, Gao H, Zhou G, Ye W, et al. Steroidal saponins from Solanum nigrum. J Nat Prod. 2006;69:1158-63 pubmed
    ..solanigrosides C-H (2-7), and one known saponin, degalactotigonin (1), were isolated from the whole plant of Solanum nigrum. Their chemical structures were elucidated using spectroscopic analysis, chemical degradation, and ..
  29. Sun Y, Zhao Y, Wang L, Lou H, Cheng A. Cloning and expression analysis of squalene synthase, a key enzyme involved in antifungal steroidal glycoalkaloids biosynthesis from Solanum nigrum. Drug Discov Ther. 2012;6:242-8 pubmed
    ..In our present study, ?-solamargine and its aglycone solasodine from Solanum nigrum were found to inhibit hyphae formation of Fusarium oxysporum...
  30. Ding X, Zhu F, Yang Y, Li M. Purification, antitumor activity in vitro of steroidal glycoalkaloids from black nightshade (Solanum nigrum L.). Food Chem. 2013;141:1181-6 pubmed publisher
    Six steroidal glycoalkaloids (1-6) were isolated and purified from Solanum nigrum L. (SNL) by acid extraction and alkaline precipitation, various chromatographic techniques, and their structures were elucidated by spectroscopic data...
  31. Rawani A, Ghosh A, Chandra G. Mosquito larvicidal and antimicrobial activity of synthesized nano-crystalline silver particles using leaves and green berry extract of Solanum nigrum L. (Solanaceae: Solanales). Acta Trop. 2013;128:613-22 pubmed publisher
    Silver nanoparticles (AgNPs) that are synthesized by using aqueous extracts of Solanum nigrum L., is a simple, non-toxic and ecofriendly green material...
  32. Kang H, Jeong H, Choi H. The chloroform fraction of Solanum nigrum suppresses nitric oxide and tumor necrosis factor-? in LPS-stimulated mouse peritoneal macrophages through inhibition of p38, JNK and ERK1/2. Am J Chin Med. 2011;39:1261-73 pubmed
    b>Solanum nigrum L., commonly known as black nightshade, is used worldwide for the treatment of skin and mucosal ulcers, liver cirrhosis and edema. We aimed to determine the anti-inflammatory active fraction of S...
  33. Bhattacharya A, Ward D, Hedden P, Phillips A, Power J, Davey M. Engineering gibberellin metabolism in Solanum nigrum L. by ectopic expression of gibberellin oxidase genes. Plant Cell Rep. 2012;31:945-53 pubmed publisher
    ..Leaf explants of Solanum nigrum (Black Nightshade; Solanaceae) were used for Agrobacterium-mediated delivery of GA-biosynthetic genes to ..
  34. Li J, Li Q, Gao D, Han Z, Lu W. Antitumor and immunomodulating effects of polysaccharides isolated from Solanum nigrum Linne. Phytother Res. 2009;23:1524-30 pubmed publisher
    We have examined the effects of the crude polysaccharides isolated from Solanum nigrum Linne (SNL-P) in vitro and in vivo against U14 cervical cancer. SNL-P showed no antiproliferative effects in vitro at a dose up to 1 mg/ml...
  35. Jeong J, de Lumen B, Jeong H. Lunasin peptide purified from Solanum nigrum L. protects DNA from oxidative damage by suppressing the generation of hydroxyl radical via blocking fenton reaction. Cancer Lett. 2010;293:58-64 pubmed publisher
    ..In this study, we report here the protective effect of lunasin purified from Solanum nigrum L. against oxidative DNA...
  36. García Andrés S, Monci F, Navas Castillo J, Moriones E. Begomovirus genetic diversity in the native plant reservoir Solanum nigrum: Evidence for the presence of a new virus species of recombinant nature. Virology. 2006;350:433-42 pubmed
    We examined the native plant host Solanum nigrum as reservoir of genetic diversity of begomoviruses that cause the tomato yellow leaf curl disease (TYLCD) emerging in southern Spain...
  37. Hartl M, Merker H, Schmidt D, Baldwin I. Optimized virus-induced gene silencing in Solanum nigrum reveals the defensive function of leucine aminopeptidase against herbivores and the shortcomings of empty vector controls. New Phytol. 2008;179:356-65 pubmed
    ..Here a VIGS system is described for Solanum nigrum, a wild relative of tomato and potato and a valuable model species for ecogenomics...
  38. Zakaria Z, Gopalan H, Zainal H, Mohd Pojan N, Morsid N, Aris A, et al. Antinociceptive, anti-inflammatory and antipyretic effects of Solanum nigrum chloroform extract in animal models. Yakugaku Zasshi. 2006;126:1171-8 pubmed
    The present study was carried out to evaluate the antinociceptive, anti-inflammatory and antipyretic effects of chloroform extract of Solanum nigrum leaves using various animal models.
  39. Gao Y, Miao C, Mao L, Zhou P, Jin Z, Shi W. Improvement of phytoextraction and antioxidative defense in Solanum nigrum L. under cadmium stress by application of cadmium-resistant strain and citric acid. J Hazard Mater. 2010;181:771-7 pubmed publisher
    ..study, we investigated the possibility of improving the phytoextraction of Cd and the antioxidative defense of Solanum nigrum L. by application of a new isolated strain (Paecilomyces lilacinus NH1) (PLNH1) and citric acid (CA)...
  40. Heo K, Lee S, Ko J, Lim K, Lim K. Glycoprotein isolated from Solanum nigrum L. inhibits the DNA-binding activities of NF-kappaB and AP-1, and increases the production of nitric oxide in TPA-stimulated MCF-7 cells. Toxicol In Vitro. 2004;18:755-63 pubmed
    b>Solanum nigrum L. (SNL) has been used in traditional folk medicine to treat numerous cancers...
  41. Hsu J, Kao S, Tu C, Li Y, Wang C. Solanum nigrum L. extract inhibits 2-acetylaminofluorene-induced hepatocarcinogenesis through overexpression of glutathione S-transferase and antioxidant enzymes. J Agric Food Chem. 2009;57:8628-34 pubmed publisher
    b>Solanum nigrum L. (SN) is a widespread plant and is regarded as a common relish in the east and the south of Taiwan. Our previous study has found that SN water extract (SNWE) alleviated carbon tetrachloride-induced liver damage in rats...
  42. Wannang N, Anuka J, Kwanashie H, Gyang S, Auta A. Anti-seizure activity of the aqueous leaf extract of Solanum nigrum linn (solanaceae) in experimental animals. Afr Health Sci. 2008;8:74-9 pubmed
    b>Solanum nigrum is claimed in traditional medical practice, to be useful in the treatment of epilepsy in some parts of Nigeria.
  43. Ji P, Sun T, Song Y, Ackland M, Liu Y. Strategies for enhancing the phytoremediation of cadmium-contaminated agricultural soils by Solanum nigrum L. Environ Pollut. 2011;159:762-8 pubmed publisher
    ..We conducted field experiments utilizing the Cd hyperaccumulator plant Solanum nigrum L., on farmland contaminated with 1.91 mg kg(-1) Cd in the soil. Our study showed that S...
  44. Nawab A, Thakur V, Yunus M, Ali Mahdi A, Gupta S. Selective cell cycle arrest and induction of apoptosis in human prostate cancer cells by a polyphenol-rich extract of Solanum nigrum. Int J Mol Med. 2012;29:277-84 pubmed publisher
    ..Here we demonstrate that a polyphenolic extract derived from ripe berries of Solanum nigrum (SN) differentially causes cell cycle arrest and apoptosis in various human prostate cancer cells without ..
  45. Ding X, Zhu F, Li M, Gao S. Induction of apoptosis in human hepatoma SMMC-7721 cells by solamargine from Solanum nigrum L. J Ethnopharmacol. 2012;139:599-604 pubmed publisher
    b>Solanum nigrum L. (SNL), a traditional Chinese medicinal herb endowed with diuretic, antipyretic and hepatoprotective effects, has been used as a major ingredient of folk prescriptions for anticancer treatment in China.
  46. Jami S, Swathi Anuradha T, Guruprasad L, Kirti P. Molecular, biochemical and structural characterization of osmotin-like protein from black nightshade (Solanum nigrum). J Plant Physiol. 2007;164:238-52 pubmed
    ..8kDa was cloned from Solanum nigrum (SniOLP). Phylogenetic analysis revealed the evolutionary conservation of this protein among diverse taxa...
  47. An L, Tang J, Liu X, Gao N. [Review about mechanisms of anti-cancer of Solanum nigrum]. Zhongguo Zhong Yao Za Zhi. 2006;31:1225-6, 1260 pubmed
    This paper gave a brief introduction of the effect of Solanum nigrum on anti-cancer. The experimental results showed that the total alkaloid isolated from S...
  48. Nirmal S, Patel A, Bhawar S, Pattan S. Antihistaminic and antiallergic actions of extracts of Solanum nigrum berries: possible role in the treatment of asthma. J Ethnopharmacol. 2012;142:91-7 pubmed publisher
    Berries of the plant Solanum nigrum Linn (Solanaceae) are used for the treatment of asthma in folk medicine and ancient books.
  49. Hsieh C, Fang H, Lina W. Inhibitory effect of Solanum nigrum on thioacetamide-induced liver fibrosis in mice. J Ethnopharmacol. 2008;119:117-21 pubmed publisher
    b>Solanum nigrum (Solanaceae) has been used in traditional folk medicine for its hepatoprotective agent...
  50. Xu J, Yin H, Li Y, Liu X. Nitric oxide is associated with long-term zinc tolerance in Solanum nigrum. Plant Physiol. 2010;154:1319-34 pubmed publisher
    ..Zn-induced NO production promoted an increase in reactive oxygen species accumulation in Solanum nigrum roots by modulating the expression and activity of antioxidative enzymes...
  51. Huang H, Syu K, Lin J. Chemical composition of Solanum nigrum linn extract and induction of autophagy by leaf water extract and its major flavonoids in AU565 breast cancer cells. J Agric Food Chem. 2010;58:8699-708 pubmed publisher
    b>Solanum nigrum Linn (SN) belongs to the Solanaceae family, is a plant growing widely in south Asia, and has been used in traditional folk medicine. It is believed to have antipyretic, diuretic, anticancer, and hepatoprotective effects...
  52. Halim V, Muck A, Hartl M, Ibáñez A, Giri A, Erfurth F, et al. A dual fluorescent/MALDI chip platform for analyzing enzymatic activity and for protein profiling. Proteomics. 2009;9:171-81 pubmed publisher
    ..Extracts of PIs from Solanum nigrum and trypsin were applied together to a pMALDI chip on which a suitable substrate was adsorbed...
  53. Zhao Y, Liu F, Lou H. [Studies on the chemical constituents of Solanum nigrum]. Zhong Yao Cai. 2010;33:555-6 pubmed
    To study the chemical constituents from Solanum nigrum. Compounds were isolated and purified by silica gel, Sephadex LH-20 and preparative HPLC. Their structures were identified by physicochemical properties and spectral analysis...
  54. el Ansary A, Mohamed A, Mahmoud S, el Bardicy S. On the pathogenicity of attenuated Schistosoma mansoni cercariae released from metabolically disturbed Biomphalaria alexandrina. J Egypt Soc Parasitol. 2003;33:777-94 pubmed
    Biomphalaria alexandrina were treated with sublethal concentrations (LC10) of dry powdered leaves Solanum nigrum or whole dry Ambrosia maritima...
  55. Agarwal A, Gahlot A, Verma R, Rao P. Effect of weed extracts on seedling growth of some varieties of wheat. J Environ Biol. 2002;23:19-23 pubmed
    Allelopathic effect ofAvena fatua L., Cyperus rotundus L., Polygonum hydropiper L., and Solanum nigrum L. were examined on seedling growth of certain commonly used varieties of wheat (Triticum aestivum L.) in the Tarai region of U.P...