salvadoraceae

Summary

Summary: A plant family of the order Celastrales, subclass Rosidae, class Magnoliopsida, a small family growing in the tropics. Members contain piperidine alkaloids and GLUCOSINOLATES.

Top Publications

  1. Almas K, Al Zeid Z. The immediate antimicrobial effect of a toothbrush and miswak on cariogenic bacteria: a clinical study. J Contemp Dent Pract. 2004;5:105-14 pubmed
    ..A toothbrush with and without toothpaste should be compared with miswak alone. Further research is needed with a larger sample size...
  2. Al Otaibi M, Al Harthy M, Gustafsson A, Johansson A, Claesson R, Angmar Månsson B. Subgingival plaque microbiota in Saudi Arabians after use of miswak chewing stick and toothbrush. J Clin Periodontol. 2004;31:1048-53 pubmed
    ..The chewing stick, the miswak, is used in many developing countries as the traditional means for oral hygiene. It is prepared from the roots, twigs and stem of Salvadora persica or other alternative local plants...
  3. Almas K, Skaug N, Ahmad I. An in vitro antimicrobial comparison of miswak extract with commercially available non-alcohol mouthrinses. Int J Dent Hyg. 2005;3:18-24 pubmed
    ..Dental professionals must exercise caution and provide guidance in assisting their patients in making informed choices regarding their use of mouthrinses for clinical efficacy...
  4. Al Teen R, Said K, Abu Alhaija E. Siwak as a oral hygiene aid in patients with fixed orthodontic appliances. Int J Dent Hyg. 2006;4:189-97 pubmed
    ..The aims of this study were to compare the mechanical efficacy of Siwak in plaque control and gingival health conditions in subjects wearing fixed orthodontic appliances compared with standard and orthodontic toothbrushes...
  5. Sofrata A, Claesson R, Lingström P, Gustafsson A. Strong antibacterial effect of miswak against oral microorganisms associated with periodontitis and caries. J Periodontol. 2008;79:1474-9 pubmed
    ..This may be attributable to the extraction process. Our aim was to test in vitro the antibacterial effect of miswak pieces, without extraction, on bacteria implicated in the etiology of periodontitis and caries...
  6. Garboui S, Borg Karlson A, Palsson K. Tick repellent properties of three Libyan plants. J Med Entomol. 2009;46:1415-9 pubmed
    Specimens of Salvadora persica Wallich (Salvadoraceae), Pistacia atlantica Desfontaines (Anacardiaceae), and Juniperus phoenicea L. (Cupressaceae) were collected at The Green Mountain in northeastern Libya...
  7. Ronse De Craene L, Wanntorp L. Floral development and anatomy of Salvadoraceae. Ann Bot. 2009;104:913-23 pubmed publisher
    ..AIMS; This study is an investigation into the floral development and anatomy of two genera of the small family Salvadoraceae, which belongs to the Brassicales in a clade with Batis and Koeberlinia...
  8. Darmani H, Nusayr T, Al Hiyasat A. Effects of extracts of miswak and derum on proliferation of Balb/C 3T3 fibroblasts and viability of cariogenic bacteria. Int J Dent Hyg. 2006;4:62-6 pubmed
    ..This study examined the effects of extracts of two chewing sticks on proliferation of fibroblasts and viability of cariogenic bacteria...
  9. Sofrata A, Lingstrom P, Baljoon M, Gustafsson A. The effect of miswak extract on plaque pH. An in vivo study. Caries Res. 2007;41:451-4 pubmed
    ..001). Rinsing with miswak extract stimulated parotid gland secretion (p < 0.01). In conclusion, miswak extract raised the plaque pH, suggesting a potential role in caries prevention...

More Information

Publications57

  1. Salem M, Behiry S, Salem A. Effectiveness of root-bark extract from Salvadora persica against the growth of certain molecularly identified pathogenic bacteria. Microb Pathog. 2018;117:320-326 pubmed publisher
    The acetone extract from root-bark of Salvadora persica L. (Salvadoraceae), is assayed for its antibacterial activity against some bacterial pathogens...
  2. Farag M, Fahmy S, Choucry M, Wahdan M, Elsebai M. Metabolites profiling reveals for antimicrobial compositional differences and action mechanism in the toothbrushing stick "miswak" Salvadora persica. J Pharm Biomed Anal. 2017;133:32-40 pubmed publisher
    Among many plant species suitable for preparing toothbrushing sticks, miswak (Salvadora persica, family Salvadoraceae) is found the most effective tool for oral hygiene. S...
  3. Alali F, Al Lafi T. GC-MS analysis and bioactivity testing of the volatile oil from the leaves of the toothbrush tree Salvadora persica L. Nat Prod Res. 2003;17:189-94 pubmed
    ..The extract can be used effectively as a natural tool for teeth cleaning and as a natural analgesic for the disturbing toothache...
  4. Haque M, Alsareii S. A review of the therapeutic effects of using miswak (Salvadora Persica) on oral health. Saudi Med J. 2015;36:530-43 pubmed publisher
    ..The present article provides a review of the various therapeutic effects of Salvadora persica on oral health, which will help to elucidate the significance and importance of this indigenous oral hygiene tool. ..
  5. Moeintaghavi A, Arab H, Khajekaramodini M, Hosseini R, Danesteh H, Niknami H. In vitro antimicrobial comparison of chlorhexidine, persica mouthwash and miswak extract. J Contemp Dent Pract. 2012;13:147-52 pubmed
  6. Antonisamy P, Duraipandiyan V, Ignacimuthu S. Anti-inflammatory, analgesic and antipyretic effects of friedelin isolated from Azima tetracantha Lam. in mouse and rat models. J Pharm Pharmacol. 2011;63:1070-7 pubmed publisher
    ..leaves collected from Kallakurichi, Villuppuram district, Tamil Nadu, India. The anti-inflammatory, analgesic and antipyretic activities of friedelin have been investigated in Wistar rats and mice...
  7. Darmani H, Al Hiyasat A, Elbetieha A, Alkofahi A. The effect of an extract of Salvadora persica (Meswak, chewing stick) on fertility of male and female mice. Phytomedicine. 2003;10:63-5 pubmed
    ..The results indicate that Meswak has adverse effects on male and female reproductive system and fertility...
  8. Chelli Chentouf N, Tir Touil Meddah A, Mullié C, Aoues A, Meddah B. In vitro and in vivo antimicrobial activity of Algerian Hoggar Salvadora persica L. extracts against microbial strains from children's oral cavity. J Ethnopharmacol. 2012;144:57-66 pubmed publisher
    ..However, they have never been tested for samples originating from Hoggar, where extreme weather conditions could lead to different properties for this Salvadora persica L. ecotype...
  9. Al Sohaibani S, Murugan K. Anti-biofilm activity of Salvadora persica on cariogenic isolates of Streptococcus mutans: in vitro and molecular docking studies. Biofouling. 2012;28:29-38 pubmed publisher
    ..The bioactive, dual-function, anti-biofilm agents in S. persica not only inhibit growth, but also control the colonization and accumulation of caries-causing S. mutans...
  10. Khalessi A, Pack A, Thomson W, Tompkins G. An in vivo study of the plaque control efficacy of Persica: a commercially available herbal mouthwash containing extracts of Salvadora persica. Int Dent J. 2004;54:279-83 pubmed
    ..This study compared the oral health efficacy of Persica mouthwash (containing an extract of Salvadora persica) with that of a placebo...
  11. Rajabalian S, Mohammadi M, Mozaffari B. Cytotoxicity evaluation of Persica mouthwash on cultured human and mouse cell lines in the presence and absence of fetal calf serum. Indian J Dent Res. 2009;20:169-73 pubmed publisher
    ..The purpose of this study was to evaluate the cytotoxic effects of Persica and chlorhexidine (CHX) mouthwashes on cultured human and mouse cell lines...
  12. El Tatari A, de Soet J, de Gee A, Abou Shelib M, van Amerongen W. Influence of Salvadora persica (miswak) extract on physical and antimicrobial properties of glass ionomer cement. Eur Arch Paediatr Dent. 2011;12:22-5 pubmed
    ..To investigate physical and antimicrobial properties of Glass Ionomer Cement (GIC) combined with Salvadora Persica Extract (SPE)...
  13. Ahmad M, Imran H, Yaqeen Z, Rehman Z, Rahman A, Fatima N, et al. Pharmacological profile of Salvadora persica. Pak J Pharm Sci. 2011;24:323-30 pubmed
    ..Phytochemical analysis was also carried out which showed the presence of certain phytoconstituents which possesses these properties. Therefore the results justified the traditional use of the plant...
  14. Balto H, Salama F, Al Mofareh S, Al Yahya F. Evaluation of different irrigating solutions on smear layer removal of primary root dentin. J Contemp Dent Pract. 2015;16:187-91 pubmed
    ..Both tested irrigant solutions have the ability to remove the intracanal smear from primary root dentin following cleaning and shaping of the root canal and could be an alternative to EDTA. ..
  15. Danaei S, Safavi A, Roeinpeikar S, Oshagh M, Iranpour S, Omidkhoda M, et al. Ion release from orthodontic brackets in 3 mouthwashes: an in-vitro study. Am J Orthod Dentofacial Orthop. 2011;139:730-4 pubmed publisher
    ..The purpose of this study was to measure the amount of metal ion release from orthodontic brackets when kept in different mouthwashes...
  16. Geetha K, Manavalan R, Venkappayya D. Control of urinary risk factors of stone formation by Salvadora persica in experimental hyperoxaluria. Methods Find Exp Clin Pharmacol. 2010;32:623-9 pubmed publisher
    ..These observations led to the conclusion that the aqueous and alcoholic extracts of the leaves of Salvadora persica are endowed with antiurolithiatic properties...
  17. Baeshen H, Birkhed D. Release of fluoride from fresh and old NaF-impregnated chewing sticks (Miswaks) in vitro and oral retention in vivo. Oral Health Prev Dent. 2010;8:93-9 pubmed
    ..The objectives of the present investigation were to study fluoride (F) release from NaF-impregnated chewing sticks (Miswaks) in vitro and to study the F clearance in saliva and the F oral retention in vivo...
  18. Khalil A. Benzylamides from Salvadora persica. Arch Pharm Res. 2006;29:952-6 pubmed
    ..Compound 2 revealed a significant inhibitory effect on human collagen-induced platelet aggregation, and a moderate antibacterial activity against Escherichia coli...
  19. Abdel Baki A, Almalki E, Mansour L, Al Quarishy S. In Vitro Scolicidal Effects of Salvadora persica Root Extract against Protoscolices of Echinococcus granulosus. Korean J Parasitol. 2016;54:61-6 pubmed publisher
    ..persica has high scolicidal power in vitro. However, in vivo effect of this material remains to be studied for treatment of echinococcosis in humans and herbivorous animals. ..
  20. Sunil C, Duraipandiyan V, Ignacimuthu S, Al Dhabi N. Antioxidant, free radical scavenging and liver protective effects of friedelin isolated from Azima tetracantha Lam. leaves. Food Chem. 2013;139:860-5 pubmed publisher
    ..These results clearly demonstrated that friedelin possessed marked antioxidant and liver protective effects...
  21. Dhankhar S, Dhankhar S, Yadav J. Investigations towards new antidiabetic drugs from fungal endophytes associated with Salvadora oleoides Decne. Med Chem. 2013;9:624-32 pubmed
    ..endophytic fungi in different solvents (methanol, acetone and aqueous) isolated from Salvadora oleoides Decne (Salvadoraceae) in glucose loaded fasting and alloxan induced diabetic Wistar albino rats...
  22. Noumi E, Snoussi M, Hajlaoui H, Valentin E, Bakhrouf A. Antifungal properties of Salvadora persica and Juglans regia L. extracts against oral Candida strains. Eur J Clin Microbiol Infect Dis. 2010;29:81-8 pubmed publisher
    ..195 mg/ml. Two C. albicans strains showed a high MIC value (3.125 mg/ml). These results indicate that extracts can contain compounds with therapeutic potential against Candida strains and, hence, their possible use as therapeutic agents...
  23. Singh A, Daing A, Dixit J. The effect of herbal, essential oil and chlorhexidine mouthrinse on de novo plaque formation. Int J Dent Hyg. 2013;11:48-52 pubmed publisher
  24. Miri A, Dorani N, Darroudi M, Sarani M. Green synthesis of silver nanoparticles using Salvadora persica L. and its antibacterial activity. Cell Mol Biol (Noisy-le-grand). 2016;62:46-50 pubmed
    ..coli and S. aureus, respectively. Also the MBC of AgNPs was 200 µg/mL for E. coli and there was no result observed for S. aureus bacteria. The results showed that synthesized nanoparticles have favorable antibacterial properties. ..
  25. Sofrata A, Santangelo E, Azeem M, Borg Karlson A, Gustafsson A, Pütsep K. Benzyl isothiocyanate, a major component from the roots of Salvadora persica is highly active against Gram-negative bacteria. PLoS ONE. 2011;6:e23045 pubmed publisher
    ..Our results indicate the need for further investigation into the mechanism of the specific killing of Gram-negative bacteria by S. persica root stick extracts and its active component benzyl isothiocyanate...
  26. Mahmood T, Ahmed E, Malik A. Structure determination of salvadorin, a novel dimeric dihydroisocoumarin from Salvadora oleoides, by NMR spectroscopy. Magn Reson Chem. 2005;43:670-2 pubmed
    ..Its chemical structure was established as 8-benzyl-6-[6-(6-ethyl-7-methyl-5,8-dihydro-2-naphthalenyl)-1-oxo-3,4-dihydro-1H-isochromen-8yl]-3, 4-dihyro-1H-isochromen-1-one, through spectroscopic techniques and chemical analysis...
  27. Neiburger E. The toothbrush plant. J Mass Dent Soc. 2009;58:30-2 pubmed
    ..The use of this wood for oral care could be a great benefit to people in industrialized nations...
  28. Aydin S, Dagli A, Ozkan Y, Kendir Y, Sahin I, Aksoy A, et al. Immunohistochemical and quantitative analysis of ghrelin in Syzygium aromaticum. Cell Biol Int. 2011;35:437-41 pubmed publisher
    ..persica. The evolutionary role of this peptide hormone in plants and animals suggests that they have evolved in a more similar way than previously thought...
  29. Abdulbaqi H, Himratul Aznita W, Baharuddin N. Evaluation of Salvadora persica L. and green tea anti-plaque effect: a randomized controlled crossover clinical trial. BMC Complement Altern Med. 2016;16:493 pubmed
    ..Longer-term clinical studies are highly encouraged to investigate its anti-plaque effect for longer periods. This study was registered in ClinicalTrials.gov as NCT02624336 in December 3, 2015. ..
  30. Farsi J, Farghaly M, Farsi N. Oral health knowledge, attitude and behaviour among Saudi school students in Jeddah city. J Dent. 2004;32:47-53 pubmed
    ..To assess the knowledge, attitude and behaviour in relation to periodontal health status among Saudi intermediate and high school students living in Jeddah, Kingdom of Saudi Arabia...
  31. Mehanna N, Reid G. Effect of Meswak (Middle Eastern tree bark) on oral pathogens and potential for probiotic applications. J Med Food. 2010;13:729-32 pubmed publisher
    ..Addition of Lactobacillus strains significantly reduced the viable counts of S. mutans. A prototype spray containing Meswak extract, lactobacilli, and mint was developed and shown to have potential as an anticaries mouthwash...
  32. Dorri M, Shahrabi S, Navabazam A. Comparing the effects of chlorhexidine and persica on alveolar bone healing following tooth extraction in rats, a randomised controlled trial. Clin Oral Investig. 2012;16:25-31 pubmed publisher
    ..2% chlorhexidine and 10% persica in enhancing extraction socket wound healing in rats. Extraction socket wound healing in rats was better enhanced with 10% persica than 0.2% chlorhexidine...
  33. Dhyani A, Arora N, Gaur S, Jain V, Sridhara S, Singh B. Analysis of IgE binding proteins of mesquite (Prosopis juliflora) pollen and cross-reactivity with predominant tree pollens. Immunobiology. 2006;211:733-40 pubmed
    ..juliflora. The findings suggest that purification of cross-reactive allergens will be helpful for diagnosis and immunotherapy of tree pollen allergic patients...
  34. Duraipandiyan V, Gnanasekar M, Ignacimuthu S. Antifungal activity of triterpenoid isolated from Azima tetracantha leaves. Folia Histochem Cytobiol. 2010;48:311-3 pubmed publisher
    ..The lowest MIC against Trichophyton rubrum (296) was 62.5 microg/ml and the MIC for Curvularia lunata was 62.5 microg/ml. These results suggest that Friedelin is a promising antifungal agent...
  35. Amoian B, Moghadamnia A, Barzi S, Sheykholeslami S, Rangiani A. Salvadora Persica extract chewing gum and gingival health: improvement of gingival and probe-bleeding index. Complement Ther Clin Pract. 2010;16:121-123 pubmed publisher
    ..Persica extract chewing gum had a considerable effect on GI, and BI. The use of Salvadora persica extract chewing gum may promote periodontal health. ..
  36. Fabian F, Mumghamba E. Risk factors for signs and symptoms of TMD in a rural adult southeast Tanzanian population. Cranio. 2008;26:44-9 pubmed
    ..Further studies are recommended to control for other confounding factors such as socio-economic status...
  37. Din M, Hussain Z, Munir H, Naz A, Intisar A, Makshoof M, et al. Microwave treated Salvadora oleoides as an eco-friendly biosorbent for the removal of toxic methyl violet dye from aqueous solution--A green approach. Int J Phytoremediation. 2016;18:477-86 pubmed publisher
    ..The results of the present research work suggest that MW-SO can be used as an environmentally friendly and economical alternative biosorbent for the removal of methyl violet dye from aqueous solutions. ..
  38. Elangovan A, Muranga J, Joseph E. Comparative evaluation of the antimicrobial efficacy of four chewing sticks commonly used in South India: an in vitro study. Indian J Dent Res. 2012;23:840 pubmed publisher
  39. Mohamed S, Khan J. Antioxidant capacity of chewing stick miswak Salvadora persica. BMC Complement Altern Med. 2013;13:40 pubmed publisher
    ..is an effective tool for oral hygiene. It possessed various biological properties including significant antibacterial and anti-fungal effects. In the present study, we evaluated the antioxidant compounds in miswak...
  40. Al Otaibi M, Al Mamari F, Baskaradoss J. Oral health status of 12-year-old school children in Yemen. A cross- sectional survey. Eur J Paediatr Dent. 2012;13:324-8 pubmed
    ..This study aims to describe the oral hygiene practices and the oral health status of 12-year-old school children of Aden, Yemen...
  41. Al Otaibi M, Angmar Månsson B. Oral hygiene habits and oral health awareness among urban Saudi Arabians. Oral Health Prev Dent. 2004;2:389-96 pubmed
    ..To analyze prevailing oral hygiene practices and oral health awareness among urban Saudi Arabians in relation to age, gender and educational level...
  42. Saeed I, Ali L, Jabeen A, Khasawneh M, Rizvi T, Ashraf S. Estrogenic activities of ten medicinal herbs from the Middle East. J Chromatogr Sci. 2013;51:33-9 pubmed publisher
  43. Baeshen H, Kjellberg H, Lingstrom P, Birkhed D. Uptake and release of fluoride from fluoride-impregnated chewing sticks (miswaks) in vitro and in vivo. Caries Res. 2008;42:363-8 pubmed publisher
    ..05 or p < 0.01). To conclude, NaF-impregnated miswaks produced a rapid release of F in vitro as well as in vivo and may be an interesting vehicle for home care use for caries prevention in countries where they are used regularly...
  44. Khan A. Monitoring structural assets of bi-species groves according to land use types: a case study from arid plains. Environ Monit Assess. 2010;168:121-31 pubmed publisher
    ..These activities affect the complimentary attributes of the bi-species groves, thus disturbing the characteristic structural features which contributed to the stability of this fragile landscape...
  45. Bennett R, Mellon F, Rosa E, Perkins L, Kroon P. Profiling glucosinolates, flavonoids, alkaloids, and other secondary metabolites in tissues of Azima tetracantha L. (Salvadoraceae). J Agric Food Chem. 2004;52:5856-62 pubmed
    Azima tetracantha L. (needle bush; bee sting bush; Salvadoraceae) is used as a food and for various herbal medicines in Africa, India, and Madagascar, but there is very little information on the secondary metabolites in this species...
  46. Tubaishat R, Darby M, Bauman D, Box C. Use of miswak versus toothbrushes: oral health beliefs and behaviours among a sample of Jordanian adults. Int J Dent Hyg. 2005;3:126-36 pubmed
  47. Sofrata A, Brito F, Al Otaibi M, Gustafsson A. Short term clinical effect of active and inactive Salvadora persica miswak on dental plaque and gingivitis. J Ethnopharmacol. 2011;137:1130-4 pubmed publisher
    ..It is one of the most important species with its reported strong antibacterial, antifungal, and antiviral effects. Mechanical removal of dental plaque is regarded as an effective mean of controlling progression of periodontal disease...
  48. Alshammary S. Effect of saline irrigation on growth characteristics and mineral composition of two local halophytes under Saudi environmental conditions. Pak J Biol Sci. 2008;11:2116-21 pubmed
    ..Among the two halophytes, A. halimus showed great potential for establishing gene banks of local species, because it has more forage value due to high protein contents than S. persica for range animals...