Summary: The buttercup plant family of the order Ranunculales, subclass Magnoliidae, class Magnoliopsida. The leaves are usually alternate and stalkless. The flowers usually have two to five free sepals and may be radially symmetrical or irregular.

Top Publications

  1. Yun Choi H, Pyo M, Chang K, Lee D. The effects of higenamine on LPS-induced experimental disseminated intravascular coagulation (DIC) in rats. Planta Med. 2002;68:326-9 pubmed
    The effect of higenamine, a benzyl-tetrahydroisoquinoline alkaloid of the roots of Aconitum spp. (Ranunculaceae), on disseminated intravascular coagulation (DIC), was investigated using an experimental DIC rat model...
  2. Despres L, Loriot S, Gaudeul M. Geographic pattern of genetic variation in the European globeflower Trollius europaeus L. (Ranunculaceae) inferred from amplified fragment length polymorphism markers. Mol Ecol. 2002;11:2337-47 pubmed
    ..The patterns of genetic variability observed in the host plant support the hypothesis of sympatric speciation in associated flies, rather than recurrent allopatric speciations...
  3. Schönswetter P, Paun O, Tribsch A, Niklfeld H. Out of the Alps: colonization of Northern Europe by East Alpine populations of the Glacier Buttercup Ranunculus glacialis L. (Ranunculaceae). Mol Ecol. 2003;12:3373-81 pubmed
    ..It is very likely therefore that R. glacialis colonized Northern Europe in postglacial times from source populations in the Eastern Alps...
  4. Di Stilio V, Kramer E, Baum D. Floral MADS box genes and homeotic gender dimorphism in Thalictrum dioicum (Ranunculaceae) - a new model for the study of dioecy. Plant J. 2005;41:755-66 pubmed
    ..In light of these findings, we discuss the potential of T. dioicum as a new model for the study of sex determination in the basal eudicots...
  5. Talent N, Dickinson T. Endosperm formation in aposporous Crataegus (Rosaceae, Spiraeoideae, tribe Pyreae): parallels to Ranunculaceae and Poaceae. New Phytol. 2007;173:231-49 pubmed
    ..They thus resemble some Sorbus (Pyreae) and very distantly related Ranunculus (Ranunculaceae). It is suggested that Paspalum (Poaceae) may have similarly flexible endosperm ploidy levels.
  6. Gallet C, Ibanez S, Zinger L, Taravel F, Trierweiler M, Jeacomine I, et al. Plant chemical defense induced by a seed-eating pollinator mutualist. J Chem Ecol. 2007;33:2078-89 pubmed
    ..europaeus to infestation by Chiastocheta larvae might be an efficient regulation mechanism of seed-predator mutualist population growth if it decreases survival or growth of the larvae...
  7. van Bel A, Hess P. Hexoses as phloem transport sugars: the end of a dogma?. J Exp Bot. 2008;59:261-72 pubmed publisher
    ..Phloem exudation facilitated by EDTA provided evidence that many of the members of two plant families (Ranunculaceae and Papaveraceae) investigated translocate >80% of carbohydrates in the form of hexoses...
  8. Shi W, Yang C, Chen J, Guo Y. Genetic variation among wild and cultivated populations of the Chinese medicinal plant Coptis chinensis (Ranunculaceae). Plant Biol (Stuttg). 2008;10:485-91 pubmed publisher
    ..590), and high gene flow between cultivars and their wild progenitors (N(m) = 7.116), might have led to the observed genetic profiles of C. chinensis...
  9. Cosendai A, Hörandl E. Cytotype stability, facultative apomixis and geographical parthenogenesis in Ranunculus kuepferi (Ranunculaceae). Ann Bot. 2010;105:457-70 pubmed publisher
    ..The wide distribution of apomicts may be further enhanced by uniparental reproduction which is advantageous for colonization. These factors are studied in the alpine species Ranunculus kuepferi...

More Information

Publications134 found, 100 shown here

  1. Ye X, Meng J, Zhao Z, Fan B, Du G. Optimal pollinator attraction strategies in Trollius ranunculoides Hemsl. (Ranunculaceae) at different altitudes: increased floral display or promotion of nectar output?. Plant Biol (Stuttg). 2011;13:551-5 pubmed publisher
    ..This strategy may improve pollination and reproductive success through visual attraction (sepal) rather than nectar reward (petal) over a gradient of decreasing pollinator abundance...
  2. Zhang R, Guo C, Zhang W, Wang P, Li L, Duan X, et al. Disruption of the petal identity gene APETALA3-3 is highly correlated with loss of petals within the buttercup family (Ranunculaceae). Proc Natl Acad Sci U S A. 2013;110:5074-9 pubmed publisher
    ..Here we show that within the buttercup family (Ranunculaceae), apetalous genera in at least seven different lineages were all derived from petalous ancestors, indicative ..
  3. Despres L, Gielly L, Redoutet B, Taberlet P. Using AFLP to resolve phylogenetic relationships in a morphologically diversified plant species complex when nuclear and chloroplast sequences fail to reveal variability. Mol Phylogenet Evol. 2003;27:185-96 pubmed
    ..Phylogenetic relationships among interfertile species of Trollius L. (Ranunculaceae) were investigated using nuclear DNA (ITS1+5...
  4. Weiss Schneeweiss H, Schneeweiss G, Stuessy T, Mabuchi T, Park J, Jang C, et al. Chromosomal stasis in diploids contrasts with genome restructuring in auto- and allopolyploid taxa of Hepatica (Ranunculaceae). New Phytol. 2007;174:669-82 pubmed
    ..Their role is investigated in the disjunctly distributed northern hemisphere Hepatica (Ranunculaceae)...
  5. Herlihy C, Eckert C. Evolutionary analysis of a key floral trait in aquilegia canadensis (ranunculaceae): genetic variation in herkogamy and its effect on the mating system. Evolution. 2007;61:1661-74 pubmed
    ..canadensis is enigmatic, and reconciling this observation will require a more integrated analysis of how herkogamy influences not only self-fertilization, but also patterns of outcross pollen import and export...
  6. Fuji S, Yamamoto H, Inoue M, Yamashita K, Fukui Y, Furuya H, et al. Complete nucleotide sequence of the genomic RNA of Aconitum latent virus (genus Carlavirus) isolated from Delphinium sp.. Arch Virol. 2002;147:865-70 pubmed
    ..The results suggest that AcLV is a distinct carlavirus species but closely related to PVM...
  7. Skipper M. Genes from the APETALA3 and PISTILLATA lineages are expressed in developing vascular bundles of the tuberous rhizome, flowering stem and flower Primordia of Eranthis hyemalis. Ann Bot. 2002;89:83-8 pubmed
    ..In addition, AP3 and PI transcripts are also found in stems and leaves. These results suggest a more complex role of B-class genes in Eranthis and possible involvement in the development of vascular tissue. ..
  8. Li J, Jin Z, Shao H. [The anti-microbial activity of the extraction from leaves of Sargentodoxa cuneata]. Zhong Yao Cai. 2005;28:906-9 pubmed
    ..The anti-bacterial activity of the extraction from the leaves of S. cuneata can be detected and the foreground of the exploitation and utilization is good. ..
  9. Prieto J, Schaffner U, Barker A, Braca A, Siciliano T, Boevé J. Sequestration of furostanol saponins by Monophadnus sawfly larvae. J Chem Ecol. 2007;33:513-24 pubmed
    ..We investigated whether secondary plant metabolites from Ranunculaceae leaves are sequestered by phymatocerine Monophadnus species, i.e...
  10. Kokoska L, Urbanová K, Kloucek P, Nedorostova L, Polesna L, Malik J, et al. Essential oils in the ranunculaceae family: chemical composition of hydrodistilled oils from Consolida regalis, Delphinium elatum, Nigella hispanica, and N. nigellastrum seeds. Chem Biodivers. 2012;9:151-61 pubmed publisher
    ..nigellastrum essential oil. Our results confirm the presence of essential oils in the family Ranunculaceae and suggest chemotaxonomical relationships within the representatives of the genera Consolida, Delphinium, and ..
  11. Hao D, Ge G, Xiao P, Wang P, Yang L. Drug metabolism and pharmacokinetic diversity of ranunculaceae medicinal compounds. Curr Drug Metab. 2015;16:294-321 pubmed
    The wide-reaching distributed angiosperm family Ranunculaceae has approximately 2200 species in around 60 genera...
  12. Salopek Sondi B, Kovac M, Prebeg T, Magnus V. Developing fruit direct post-floral morphogenesis in Helleborus niger L. J Exp Bot. 2002;53:1949-57 pubmed
  13. Wang R, Yang X, Ma C, Cai S, Xu T. [Analysis of fatty acids from the flowers of Trollius chinensis]. Zhong Yao Cai. 2010;33:1579-81 pubmed
    ..The major fatty acids were hexadecanoic (19.85%), (Z,Z)-9,12-octadecadienoic (14.37%), tetradecanoic (13.93%), (Z)-9-octadecenoic (13.00%), dodecanoic (6.79%), 10-hydroxy-hexadecanoic (4.37%) and octadecanoic (3.34%) acids. ..
  14. Jabbour F, Renner S. A phylogeny of Delphinieae (Ranunculaceae) shows that Aconitum is nested within Delphinium and that Late Miocene transitions to long life cycles in the Himalayas and Southwest China coincide with bursts in diversification. Mol Phylogenet Evol. 2012;62:928-42 pubmed publisher
    The tribe Delphinieae (Ranunculaceae) comprises two species-rich genera, Aconitum and Delphinium, the latter including Consolida and Aconitella...
  15. Mlinarec J, Satovic Z, Mihelj D, Malenica N, Besendorfer V. Cytogenetic and phylogenetic studies of diploid and polyploid members of tribe Anemoninae (Ranunculaceae). Plant Biol (Stuttg). 2012;14:525-36 pubmed publisher
  16. Kang X, Fan Z, Zhang Z. [Study on the optimum extracting conditions of total alkaloids and aconitine in Aconitum szechenyianum Gay]. Zhong Yao Cai. 2007;30:715-8 pubmed
    ..5 h with 3 times. Contents of total alkaloids and aconitine in Aconitum szechenyianum Gay. were 0.980% and 0.109%, respectively. Through the test and verify, the optimum extraction methods of total alkaloids and aconitine are rational. ..
  17. Gao H, Zhao F, Chen G, Chen S, Yu Y, Yao Z, et al. Bidesmoside triterpenoid glycosides from Stauntonia chinensis and relationship to anti-inflammation. Phytochemistry. 2009;70:795-806 pubmed publisher
    ..That is, the major components might be biologically active not directly, but via biochemical transformation in vivo. Hence, we propose a "traditional medicine's prodrug characteristic" concept. ..
  18. Jaroszewski J, Staerk D, Holm Móller S, Jensen T, Franzyk H, Somanadhan B. Naravelia zeylanica [corrected] occurrence of primary benzamides in flowering plants. Nat Prod Res. 2005;19:291-4 pubmed
    Extract of Naravelia zeylanica (Ranunculaceae) yielded three simple benzamides, 3,4-methylenedioxybenzamide, 4-methoxybenzamide and 4-hydroxy-3-methoxybenzamide...
  19. Ibanez S, Dötterl S, Anstett M, Baudino S, Caissard J, Gallet C, et al. The role of volatile organic compounds, morphology and pigments of globeflowers in the attraction of their specific pollinating flies. New Phytol. 2010;188:451-63 pubmed publisher
    ..However, their relative roles and the intensity of the selective pressures exerted on floral traits by pollinators appear to vary in time and space. ..
  20. Han S, Kim S, Yang C, Seo J. Genetical identification of Akebia and Aristolochia species by using Pyrosequencing. J Biotechnol. 2005;120:360-3 pubmed
    ..The Pyrosequencing analysis of A. quinata Decaisne was very different compared with that of A. manshuriensis Kom. Pyrosequencing analyses might be able to identify the Akebia and Aristolochia species. ..
  21. Zhao D, Li Y, Ding W, Ding J, Sun Z. [Quality testing and quality classification standard establishment of Trollius chinensis seeds]. Zhongguo Zhong Yao Za Zhi. 2011;36:3421-4 pubmed
    ..Quality of T. chinensis seeds from different producing areas was analyzed, and the primary T. chinensis seed quality classification standard was established. ..
  22. Shao Y, Xu X, Li Y, Qi X, Wang K, Wu Y, et al. Paeoniflorin inhibits high glucose-induced macrophage activation through TLR2-dependent signal pathways. J Ethnopharmacol. 2016;193:377-386 pubmed publisher
    Paeoniflorin(PF), extracted from the root peeled of Paeonia lactiflora Pall(Family: Ranunculaceae), has therapeutic potential in many animal models of inflammatory diseases...
  23. Goyal S, Prajapati C, Gore P, Patil C, Mahajan U, Sharma C, et al. Therapeutic Potential and Pharmaceutical Development of Thymoquinone: A Multitargeted Molecule of Natural Origin. Front Pharmacol. 2017;8:656 pubmed publisher
    ..that is popularly known as black cumin or black seed and belongs to the family Ranunculaceae. A large number of studies have revealed that thymoquinone is the major active constituent in N...
  24. Yoshimitsu H, Miyashita H, Nishida M, Mineno T, Nohara T. Dolabellane diterpene and three cycloartane glycosides from Thalictrum squarrosum. Chem Pharm Bull (Tokyo). 2010;58:1043-6 pubmed
    ..named squarrosides V, VI, and VII, have been isolated from the dried aerial parts of Thalictrum squarrosum (Ranunculaceae). Their structures were determined by two dimensional (2D) NMR spectroscopic analysis and chemical evidence.
  25. McEwen J, Vamosi J, Rogers S. Natural selection and neutral evolution jointly drive population divergence between alpine and lowland ecotypes of the allopolyploid plant Anemone multifida (Ranunculaceae). PLoS ONE. 2013;8:e68889 pubmed publisher
  26. Hao D, Xiao P, Ma H, Peng Y, He C. Mining chemodiversity from biodiversity: pharmacophylogeny of medicinal plants of Ranunculaceae. Chin J Nat Med. 2015;13:507-20 pubmed publisher
    This paper reports a pharmacophylogenetic study of a medicinal plant family, Ranunculaceae, investigating the correlations between their phylogeny, chemical constituents, and pharmaceutical properties...
  27. Xiang K, Zhao L, Erst A, Yu S, Jabbour F, Wang W. A molecular phylogeny of Dichocarpum (Ranunculaceae): Implications for eastern Asian biogeography. Mol Phylogenet Evol. 2017;107:594-604 pubmed publisher
    ..and trnH-psbA) and nuclear (ITS) DNA sequences to investigate the historical biogeography of Dichocarpum (Ranunculaceae), an eastern Asian endemic genus throughout warm-temperate and subtropical forests of the area...
  28. Chung T, Lee J, Choi H, Park M, Kim E, Han J, et al. Anemone rivularis inhibits pyruvate dehydrogenase kinase activity and tumor growth. J Ethnopharmacol. 2017;203:47-54 pubmed publisher
    Anemone rivularis Buch.-Ham. ex DC. (Ranunculaceae) have been used as a traditional remedy for treatment of inflammation and cancer. However, there is no report demonstrating experimental evidence on anti-tumor action of A. rivularis...
  29. Zhou X, Fan G. [Study on purification of total flavones from Trollius ledebouri by macroporous resin]. Zhong Yao Cai. 2009;32:1450-4 pubmed
    ..0, the ratio of sample to D101 macroporous resin was 1:1 (W/W), 4 BV of water was used as purificant and 6 BV of 30% alcohol was used as eluant. Under these conditions, the average content of total flavonoids extract was over 60%. ..
  30. Dong H, Yan G, Han Y, Sun H, Zhang A, Li X, et al. UPLC-Q-TOF/MS-based metabolomic studies on the toxicity mechanisms of traditional Chinese medicine Chuanwu and the detoxification mechanisms of Gancao, Baishao, and Ganjiang. Chin J Nat Med. 2015;13:687-98 pubmed publisher
    ..Chuanwu (CW), a famous traditional Chinese medicine (TCM) from the mother roots of Aconitum carmichaelii Debx.. (Ranunculaceae), has been used for the treatment of various diseases...
  31. Oh A, Oh B. Development and characterization of 24 chloroplast microsatellite markers for two species of Eranthis (Ranunculaceae). Mol Biol Rep. 2017;44:359-363 pubmed publisher
    Chloroplast microsatellites for two Korean endemic species, Eranthis byunsanensis and E. pungdoensis (Ranunculaceae), were isolated to address the questions of their distributional patterns and evolutionary relationships, using next-..
  32. Metin A, Calka O, Akdeniz N, Behçet L. Phytodermatitis from Ceratocephalus falcatus. Contact Dermatitis. 2005;52:314-6 pubmed
    Ceratocephalus falcatus (L.) Pers. (Ranunculaceae) is a wild plant. It grows abundantly in the Van province. The species of Ceratocephalus genus possess irritant properties from the presence of an innocuous glycoside, ranunculin...
  33. Zou J, Yang J, Zhou L, Lin G. A new labdane type diterpenoid from Trollius ledebouri. Nat Prod Res. 2006;20:1031-5 pubmed
    ..The absolute stereostructure was elucidated on the basis of the spectroscopic analysis. ..
  34. Farrow S, Hagel J, Facchini P. Transcript and metabolite profiling in cell cultures of 18 plant species that produce benzylisoquinoline alkaloids. Phytochemistry. 2012;77:79-88 pubmed publisher
    ..Taken together, these data represent an important tool for the discovery of BIA biosynthetic genes. ..
  35. Schaeffer R, Phillips C, Duryea M, Andicoechea J, Irwin R. Nectar yeasts in the tall Larkspur Delphinium barbeyi (Ranunculaceae) and effects on components of pollinator foraging behavior. PLoS ONE. 2014;9:e108214 pubmed publisher
    ..by assessing the abundance and diversity of yeasts associated with the perennial larkspur Delphinium barbeyi (Ranunculaceae) and testing whether their presence affected components of pollinator foraging behavior...
  36. Bartkowska M, Wong A, Sagar S, Zeng L, Eckert C. Lack of spatial structure for phenotypic and genetic variation despite high self-fertilization in Aquilegia canadensis (Ranunculaceae). Heredity (Edinb). 2018;121:605-615 pubmed publisher
  37. Wu J, Guo Z, Zhu Y, Huang Z, Gong X, Li Y, et al. A systematic review of pharmacokinetic studies on herbal drug Fuzi: Implications for Fuzi as personalized medicine. Phytomedicine. 2018;44:187-203 pubmed publisher
    Fuzi, which is the processed lateral roots of Aconitum carmichaeli Debx. (Ranunculaceae), is a traditional herbal medicine that is well known for its excellent pharmacological effects and acute toxicity...
  38. Niu X, Li W, Li Y, Du Q. [Microscopy identification of Caltha palustris L. var. membranacea Turcz]. Zhong Yao Cai. 2003;26:171-2 pubmed
    ..There are crystals in root and mesophyll from Caltha palustris L. var. membrancea Turcz.. Anomocytic type stomata are visible. Above mentioned characters can be used for the identification of Caltha palustris L. var. membranacea Turcz. ..
  39. Wang Y, Luo Y, Chen C, Li N, She Y, Zhang L. The influence of the total flavonoids of Hedysarum polybotry on the proliferation, cell cycle, and expressions of p21Ras and proliferating cell nuclear antigen gene in erythroleukemia cell line K562. Chin J Integr Med. 2012;18:385-90 pubmed publisher
    ..The inhibitory effect on proliferation of K562 cells was observed in the groups treated with flavonoids of Hedysarum polybotry, which might be related to cells arresting. ..
  40. Raza M, Shaheen F, Choudhary M, Sombati S, Rafiq A, Suria A, et al. Anticonvulsant activities of ethanolic extract and aqueous fraction isolated from Delphinium denudatum. J Ethnopharmacol. 2001;78:73-8 pubmed
    ..The results suggest the presence of potent anticonvulsant compounds in AF of D. denudatum and deserve further investigation for isolation of active compounds and elucidation of the mechanism of anticonvulsant action. ..
  41. Inbaraj J, Kukielczak B, Bilski P, Sandvik S, Chignell C. Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.) 1. Berberine. Chem Res Toxicol. 2001;14:1529-34 pubmed
    ..These findings suggest that exposure to sunlight or artificial light sources emitting UVA should be avoided when topical preparations derived from Goldenseal or containing berberine are used. ..
  42. Zhang Q, Ye W, Hsiao W, Zhao S, Che C. Cycloartane glycosides from Cimicifuga dahurica. Chem Pharm Bull (Tokyo). 2001;49:1468-70 pubmed
    ..along with four known cycloartane compounds, were isolated from the rhizomes of Cimicifuga dahurica (Ranunculaceae)...
  43. Tian Z, Zhou L, Huang F, Chen S, Yang J, Wu E, et al. Anti-cancer activity and mechanisms of 25-anhydrocimigenol-3-O-beta-D-xylopyranoside isolated from Souliea vaginata on hepatomas. Anticancer Drugs. 2006;17:545-51 pubmed
    ..Moreover, ACX also exhibited a dose-dependent inhibition of tumor growth on mice implanted with H22 in vivo. These findings implicate ACX as a promising anti-cancer agent for chemotherapy of certain cancers. ..
  44. Buchner O, Lutz C, Holzinger A. Design and construction of a new temperature-controlled chamber for light and confocal microscopy under monitored conditions: biological application for plant samples. J Microsc. 2007;225:183-91 pubmed
  45. Orellana M, López Pujol J, Blanché C, Rovira A, Bosch M. Genetic diversity in Delphinium staphisagria (Ranunculaceae), a rare Mediterranean dysploid larkspur with medicinal uses. Genetica. 2009;135:221-32 pubmed publisher
    ..The limited genetic variability, the high genetic similarity among populations and the dysploidy of this species make it worthy of conservation. Management strategies are proposed mainly to preserve its genetic pool. ..
  46. Zhu H, Chen J, Chen L, An Z. [Pharmacognostical study of tall monkshood root]. Zhong Yao Cai. 2008;31:30-2 pubmed
    ..These character can provide scientific basis for its quality standard and development. ..
  47. Radesky J, Zuckerman B, Silverstein M, Rivara F, Barr M, Taylor J, et al. Inconsolable infant crying and maternal postpartum depressive symptoms. Pediatrics. 2013;131:e1857-64 pubmed publisher
    ..Asking a mother about her ability to soothe her infant may be more relevant for potential intervention than questions about crying and fussing duration alone. ..
  48. Zhan C, Ahmed S, Hu S, Dong S, Cai Q, Yang T, et al. Cytochrome P450 CYP716A254 catalyzes the formation of oleanolic acid from ?-amyrin during oleanane-type triterpenoid saponins biosynthesis in Anemone flaccida. Biochem Biophys Res Commun. 2018;495:1271-1277 pubmed publisher
    Anemone flaccida Fr. Shmidt (Ranunculaceae), known as 'Di Wu' in China, is a perennial herb which has long been used to treat arthritis. The rhizome of A. flaccida contains pharmacologically active components i.e...
  49. Chen S, Li W, Fabricant D, Santarsiero B, Mesecar A, Fitzloff J, et al. Isolation, structure elucidation, and absolute configuration of 26-deoxyactein from Cimicifuga racemosa and clarification of nomenclature associated with 27-deoxyactein. J Nat Prod. 2002;65:601-5 pubmed
    ..The structures and absolute stereochemistry of 1 and 2 were established by spectroscopic methods (FABMS, (1)H and (13)C NMR) and single-crystal X-ray data analysis. ..
  50. Freudenstein J, Dasenbrock C, Nisslein T. Lack of promotion of estrogen-dependent mammary gland tumors in vivo by an isopropanolic Cimicifuga racemosa extract. Cancer Res. 2002;62:3448-52 pubmed
  51. Chen J, Chen X. [Pharmacognostic identification of medicinal Asteropyrum plants in China]. Zhongguo Zhong Yao Za Zhi. 2002;27:94-7 pubmed
    ..To offer evidences for quality control of medicinal Asteropyrum plants...
  52. Zou J, Yang J, Dong Y, Zhou L, Lin G. Flavone C-glycosides from flowers of Trollius ledebouri. Phytochemistry. 2005;66:1121-5 pubmed
    ..Their structures were elucidated by means of UV, IR, MS and NMR spectroscopic analyses. ..
  53. Van der Welle M, Niggebrugge K, Lamers L, Roelofs J. Differential responses of the freshwater wetland species Juncus effusus L. and Caltha palustris L. to iron supply in sulfidic environments. Environ Pollut. 2007;147:222-30 pubmed
    ..The results of our experiments confirm that iron-rich groundwater discharge has the potential to affect vegetation composition through toxicity modification in sulfidic environments...
  54. Diaz J, Carmona A, Torres F, Quintana J, Estevez F, Herz W. Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana. Planta Med. 2008;74:171-4 pubmed publisher
  55. Zhang H, Dong Y, Hu S, Ren S. [The comparison about inhibition of five Chinese herbal medicines to two different resources alpha-glycosidase]. Zhong Yao Cai. 2008;31:1024-7 pubmed
    ..To compare alpha-glycosidase inhibitor microamount screening models which are established by two different resources alpha-glycosidase to screen the Chinese herbal medicines which have great alpha-glycosidase inhibition...
  56. Wang L, Ye X, Chen Z, Li X, Sun Q, Zhang B, et al. Synthesis and antimicrobial activity of 3-octyloxy-8-alkyljatrorrhizine derivatives. J Asian Nat Prod Res. 2009;11:365-70 pubmed publisher
    ..The 3-octyloxy-8-butyljatrorrhizine displayed the highest antimicrobial activity in all compounds. Their structure-activity relationships were discussed. ..
  57. Rief A, Knapp B, Seeber J. Palatability of selected alpine plant litters for the decomposer Lumbricus rubellus (Lumbricidae). PLoS ONE. 2012;7:e45345 pubmed publisher
    ..rubellus. We conclude that L. rubellus is a widespread, adaptable ubiquist, which is able to feed on a variety of food sources differing in quality and palatability, as long as they have been exposed to wheathering. ..
  58. Ju J, Liu D, Lin G, Zhang Y, Yang J, Lu Y, et al. Beesiosides G, H, and J-N, seven new cycloartane triterpene glycosides from Beesia calthifolia. J Nat Prod. 2002;65:147-52 pubmed
  59. Lynn D, Waldren S. Physiological variation in populations of Ranunculus repens L. (creeping buttercup) from the temporary limestone lakes (turloughs) in the west of Ireland. Ann Bot. 2002;89:707-14 pubmed
  60. Bylka W. Comparative studies and quantitative determination of flavonoid compounds in the flowers of some species of the Aquilegia L. genus. Acta Pol Pharm. 2001;58:469-71 pubmed
    ..A. caerulea James, A. canadensis L., A. pyrenaica D.C., were co-chromatographed with the flavonoids and the extract from A. vulgaris L. The content of flavonoids in these species were determined by the Christ-Müller method. ..
  61. Kim S, Ban S, Chung H, Choi D, Choi P, Yoo O, et al. Taxonomic discrimination of higher plants by pyrolysis mass spectrometry. Plant Cell Rep. 2004;22:519-22 pubmed
    ..These results indicate that PyMS is able to discriminate higher plants based on taxonomic classification at the family, genus, species, and variety level. ..
  62. Sun P, Luo G. [LC-MS analysis of three kinds of Mutong medicinal materials]. Zhong Yao Cai. 2004;27:898-901 pubmed
    Three kinds of Mutong medicinal materials (Lardizabalaceae, Ranunculaceae, Aristolochiaceae) were analyzed qualitatively by LC-MS...
  63. Lee J, Baum S, Oh S, Jiang C, Chen J, Bowman J. Recruitment of CRABS CLAW to promote nectary development within the eudicot clade. Development. 2005;132:5021-32 pubmed publisher
  64. Marín C, Boutaleb Charki S, Diaz J, Huertas O, Rosales M, Perez Cordon G, et al. Antileishmaniasis activity of flavonoids from Consolida oliveriana. J Nat Prod. 2009;72:1069-74 pubmed publisher
    ..peruviana, while 2a as well as 4 were effective against Leishmania (V.) braziliensis. These compounds were not cytotoxic and are effective at similar concentrations up to or lower than the reference drugs (pentostam and glucantim). ..
  65. Sun Y, Yuan H, Hao L, Min C, Cai J, Liu J, et al. Enrichment and antioxidant properties of flavone C-glycosides from trollflowers using macroporous resin. Food Chem. 2013;141:533-41 pubmed publisher
    ..The separation process was high-efficient, low-cost and environmental-friendly, which could afford a potential approach for industrial applications. ..
  66. Li J, Jin Z, Chen T, Gu Q. [Correlation of anti-bacterial activity with secondary metabolites content in Sargentodoxa Cuneata tables]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2006;35:273-80 pubmed
    ..There is significant correlation of the anti-bacterial activity with the content of total saponin, total tannin, dissociated emodin and total chlorogenic acid in S. cuneata tables. ..
  67. Ibanez S, Dujardin G, Despres L. Stability of floral specialization in Trollius europaeus in contrasting ecological environments. J Evol Biol. 2009;22:1183-92 pubmed publisher
    ..Selection in favour of the closed phenotype was even more intense in patches where open phenotypes were most common, precluding the evolution of open flowers in the study populations. ..
  68. Xu K, Xu X, Deng W, Zhang L, Wang M, Ding L. Three new flavone C-glycosides from the aerial parts of Paraquilegia microphylla. J Asian Nat Prod Res. 2011;13:409-16 pubmed publisher
  69. Espíndola A, Pellissier L, Maiorano L, Hordijk W, Guisan A, Alvarez N. Predicting present and future intra-specific genetic structure through niche hindcasting across 24 millennia. Ecol Lett. 2012;15:649-57 pubmed publisher
    ..Our interdisciplinary approach, applicable to virtually any taxon, is an advance in inferring how climate change impacts species' genetic structures. ..
  70. Brütting C, Hensen I, Wesche K. Ex situ cultivation affects genetic structure and diversity in arable plants. Plant Biol (Stuttg). 2013;15:505-13 pubmed publisher
    ..One option is cold storage of seeds, a practice that is not currently followed in the studied ex situ collections. This may reflect that the respective gardens focus on displaying living plant populations...
  71. Basi Z, Turkoglu V. Purification of angiotensin converting enzyme from human plasma and investigation of the effect of some active ingredients isolated from Nigella sativa L. extract on the enzyme activity. Biomed Chromatogr. 2017;: pubmed publisher
    ..Natural fatty acids of Nigella sativa (Ranunculaceae) were isolated by means of column chromatography...
  72. Li X, Huo T, Qin F, Lu X, Li F. Determination and pharmacokinetics of orientin in rabbit plasma by liquid chromatography after intravenous administration of orientin and Trollius chinensis Bunge extract. J Chromatogr B Analyt Technol Biomed Life Sci. 2007;853:221-6 pubmed
    ..530-53.0 microg/mL. This validated method was successfully applied to a pharmacokinetic study in rabbits after the intravenous administrations of orientin and TRO PE at three different doses. ..
  73. Shang X, Tao C, Miao X, Wang D, Tangmuke -, Dawa -, et al. Ethno-veterinary survey of medicinal plants in Ruoergai region, Sichuan province, China. J Ethnopharmacol. 2012;142:390-400 pubmed publisher
    ..In these medicine, 93 species were native and Ranunculaceae (12, 12.90%), Compositae (11, 11.83%), Papaveraceae (7, 7.53%) were the predominant families...
  74. Iwasa K, Moriyasu M, Wiegrebe W. Some contributions to the application of LC-NMR, LC-MS, and LC-CD to the biosynthesis of isoquinoline alkaloids using callus cultures. Pharmazie. 2012;67:571-85 pubmed
    ..Some new alkaloids of these types have been found...
  75. Suszko A, Obminska Mrukowicz B. Influence of polysaccharide fractions isolated from Caltha palustris L. on the cellular immune response in collagen-induced arthritis (CIA) in mice. A comparison with methotrexate. J Ethnopharmacol. 2013;145:109-17 pubmed publisher
    ..These results are similar to those obtained in the case of MTX treatment. This indicates that fraction B may be a potent candidate for botanical anti-arthritic agent. ..
  76. Arslan B, Isik F, Gür H, Ozen F, Catal T. Apoptotic Effect of Nigella sativa on Human Lymphoma U937 Cells. Pharmacogn Mag. 2017;13:S628-S632 pubmed publisher
    i>Nigella sativa is from botanical Ranunculaceae family and commonly known as black seed. Apoptotic effect of N. sativa and its apoptotic signaling pathways on U937 lymphoma cells are unknown.
  77. Li R, Lin G, Leach D, Waterman P, Myers S. Inhibition of COXs and 5-LOX and activation of PPARs by Australian Clematis species (Ranunculaceae). J Ethnopharmacol. 2006;104:138-43 pubmed
    The species of Clematis (Ranunculaceae) have been traditionally used for inflammatory conditions by indigenous Australians. We have previously reported that the ethanol extract of Clematis pickeringii inhibited COX-1...
  78. Kim S, Shin J, Lee J, Yin S, Kai M, Lee M. Effects of hydrastine derivatives on dopamine biosynthesis in PC12 cells. Planta Med. 2001;67:609-13 pubmed
    ..4 % inhibition relative to the control level in PC12 cells. These results suggest that (1R,9S)-beta-hydrastine hydrochloride contributes partially to the decrease in dopamine content by the inhibition of TH activity in PC12 cells...
  79. Ruiz Mesía L, Madinaveitia A, Reina M, Rodríguez M, De la Fuente G, Ruiz Mesía W. Four new alkaloids from Consolida glandulosa. J Nat Prod. 2002;65:496-9 pubmed
    ..All the structures of these compounds were substantiated by a single-crystal X-ray analysis performed on compound 3...
  80. Zhang W, Li J, Li H, Liu X. [Analysis on age structure and dynamics of Kindonia uniflora populations]. Ying Yong Sheng Tai Xue Bao. 2004;15:561-5 pubmed
    ..uniflora populations depended on the habitats; therefore, the communities in which K. uniflora population lived should be conserved firstly. The in-situ conservation of the populations should be encouraged...
  81. Despres L, Ibanez S, Hemborg A, Godelle B. Geographic and within-population variation in the globeflower-globeflower fly interaction: the costs and benefits of rearing pollinators' larvae. Oecologia. 2007;151:240-50 pubmed
    ..The apparent alignment of interests between fly and plants (positive relationship between numbers of seed released and destroyed) is shown to hide a conflict of interest found when flower size is controlled for...
  82. Guan S, Xia J, Lu Z, Chen G, Jiang B, Liu X, et al. Structure elucidation and NMR spectral assignments of three new lignan glycosides from Akebia trifoliata. Magn Reson Chem. 2008;46:186-90 pubmed
    ..The NMR assignments for the compounds were carried out using 1H, 13C, DEPT, COSY, HSQC, HMBC and ROESY NMR experiments...
  83. Zhong X, Shi W, Ma A, Gong X, Zhai X, Zhang T, et al. Effects of Radix scutellariae and Rhizoma atractylodis on LPS-induced abortion and the uterine IL-10 contents in mice. Am J Chin Med. 2008;36:141-8 pubmed
    ..The study indicates that the anti-abortive effects of PXF and the combination of Radix scutellariae and Rhizoma atractylodis are closely related to up-regulation of the Th2 cytokine IL-10 at the maternal fetal interface...
  84. Biton E, Gildor H. The seasonal effect in one-dimensional Daisyworld. J Theor Biol. 2012;314:145-56 pubmed publisher
    ..Applications to other SRF fluctuation, as Milankovitch cycles are discussed...
  85. Zedlitz S, Kaufmann R, Boehncke W. Allergic contact dermatitis from black cumin (Nigella sativa) oil-containing ointment. Contact Dermatitis. 2002;46:188 pubmed
  86. Wang H, Ng T. Concurrent isolation of a Kunitz-type trypsin inhibitor with antifungal activity and a novel lectin from Pseudostellaria heterophylla roots. Biochem Biophys Res Commun. 2006;342:349-53 pubmed
    ..The novel aspects of the present report include demonstration of antifungal activity in Kunitz-type trypsin inhibitors and isolation of a novel lectin as well as a trypsin inhibitor from roots...
  87. Peng Y, Chen S, Liu Y, Wang L, Xiao P. [Pharmaphylogenetic study on isopyroideae (Ranunculaceae)]. Zhongguo Zhong Yao Za Zhi. 2006;31:1210-4 pubmed
    To study the pharmaphylogenetic of medicinal plants of Isopyroideae (Ranunculaceae).
  88. Wang R, Wu X, Liu L, An Y. Activity directed investigation on anti-inflammatory fractions and compounds from flowers of Trollius chinensis. Pak J Pharm Sci. 2014;27:285-8 pubmed
    ..As a result, flavonoids and phenolics were demonstrated to be the major anti-inflammatory components. ..
  89. Davis S. Allocation to floral structures in Thalictrum pubescens (Ranunculaceae), a cryptically dioecious species. Ann Bot. 2002;90:119-26 pubmed
    ..In conclusion, stamen production does not appear to be inconsequential to females of Thalictrum pubescens...
  90. Hao G, Zhao W, Lei Y, Yang Y, Zhi Hong Y, Nai Li W, et al. Five new bidesmoside triterpenoid saponins from Stauntonia chinensis. Magn Reson Chem. 2008;46:630-7 pubmed publisher
  91. Mikage M, Hutagi Y. [Herbological study on the botanical origin of the Chinese crude drug shan-zhu-yu]. Yakushigaku Zasshi. 2008;43:33-9 pubmed
    ..The plants of Elaeagnus, of the family Elaeagnaceae, were possibly used in ancient Japan. Cornus officinalis was determined to be the origin of Shan-zhu-yu during the Qing Dynasty, China...
  92. Li Z, Li D, Hua H, Chen X, Kim C. Three new acylated flavone C-glycosides from the flowers of Trollius chinensis. J Asian Nat Prod Res. 2009;11:426-32 pubmed publisher
    ..The structural elucidations of these compounds were carried out by a detailed analysis of the NMR and MS spectra...