Summary: A plant family of the order Primulales, subclass Dilleniidae, class Magnoliopsida.

Top Publications

  1. Hirota M, Miyazaki S, Minakuchi T, Takagi T, Shibata H. Myrsinoic acids B, C and F, anti-inflammatory compounds from Myrsine seguinii. Biosci Biotechnol Biochem. 2002;66:655-9 pubmed
    ..These compounds suppressed the TPA-induced edema of mouse ear, myrsinoic acid F being the most active (IE 77% at a dose of 0.56 micromol)...
  2. Tadesse D, Eguale T, Giday M, Mussa A. Ovicidal and larvicidal activity of crude extracts of Maesa lanceolata and Plectranthus punctatus against Haemonchus contortus. J Ethnopharmacol. 2009;122:240-4 pubmed
  3. Arot Manguro L, Midiwo J, Kraus W, Ugi I. Benzoquinone derivatives of Myrsine africana and Maesa lanceolata. Phytochemistry. 2003;64:855-62 pubmed
    ..Their structural elucidation was achieved by spectroscopic measurements including 2D NMR experiments...
  4. Gathuma J, Mbaria J, Wanyama J, Kaburia H, Mpoke L, Mwangi J. Efficacy of Myrsine africana, Albizia anthelmintica and Hilderbrantia sepalosa herbal remedies against mixed natural sheep helminthosis in Samburu district, Kenya. J Ethnopharmacol. 2004;91:7-12 pubmed
    ..The group of sheep treated with Albizia anthelmintica showed a significant increase (P=0.003) in packed cell volume (PCV)...
  5. Dötterl S, Schäffler I. Flower scent of floral oil-producing Lysimachia punctata as attractant for the oil-bee Macropis fulvipes. J Chem Ecol. 2007;33:441-5 pubmed
    ..Flower and oil extracts attracted the bees, and some of the compounds identified are seldom found in the floral scent of other plants; these may have been responsible for the attraction of the bees. ..
  6. Liu Y, Tam N, Yang J, Pi N, Wong M, Ye Z. Mixed heavy metals tolerance and radial oxygen loss in mangrove seedlings. Mar Pollut Bull. 2009;58:1843-9 pubmed publisher
    ..Therefore, we conclude that both ROL amount and "tight" barrier spatial ROL pattern in the roots of the mangrove seedlings play an important role in resistance to heavy metal toxicity. ..
  7. Han W, Xiang W, Ye D, Lu S, Ding T, Li X. [Spatial patterns of and specific correlations between dominant tree species in a karst evergreen and deciduous broadleaved mixed forest in Mulun Karst National Nature Reserve]. Ying Yong Sheng Tai Xue Bao. 2010;21:2769-76 pubmed
    ..japonicum at scale <50 m, no significant correlation for S. wightianum, and no significant correlation for R. kwangsiensis at scale <20 m but significant negative correlation at scale 20-50 m. ..
  8. Liu Y, Sun H, Chen G. [Effects of PCBs on Aegiceras corniculatum seedlings growth and membrane protective enzyme system]. Ying Yong Sheng Tai Xue Bao. 2007;18:123-8 pubmed
    ..It was suggested that A. corniculatum could endure and adapt definite concentrations of PCBs through physiological and biochemical mechanisms, being available to the phytoremediation of PCBs pollution. ..
  9. Yeong L, Abdul Hamid R, Saiful Yazan L, Khaza Ai H, Mohtarrudin N. Low dose triterpene-quinone fraction from Ardisia crispa root precludes chemical-induced mouse skin tumor promotion. BMC Complement Altern Med. 2015;15:431 pubmed publisher
    ..Apart from its traditional usages against various ailments, Ardisia crispa (Family: Myrsinaceae) specifically its triterpene-quinone fraction (TQF) which was isolated from the root hexane extract (ACRH) was ..

More Information


  1. Zhao B, Zhou Y, Chen G. The effect of mangrove reforestation on the accumulation of PCBs in sediment from different habitats in Guangdong, China. Mar Pollut Bull. 2012;64:1614-9 pubmed publisher
    ..It was suggested that the native mangrove species Kandelia candel and Aegiceras corniculatum could represent good choices for the phytoremediation of PCB contamination. ..
  2. Chaturvedula V, Schilling J, Miller J, Andriantsiferana R, Rasamison V, Kingston D. New cytotoxic bis 5-alkylresorcinol derivatives from the leaves of Oncostemon bojerianum from the Madagascar rainforest. J Nat Prod. 2002;65:1627-32 pubmed
    ..All the compounds exhibited cytotoxic activity against the A2780 ovarian cancer cell line. ..
  3. Dahdouh Guebas F, Collin S, Lo Seen D, Rönnbäck P, Depommier D, Ravishankar T, et al. Analysing ethnobotanical and fishery-related importance of mangroves of the East-Godavari Delta (Andhra Pradesh, India) for conservation and management purposes. J Ethnobiol Ethnomed. 2006;2:24 pubmed
  4. Azam S, Bashir S, Ahmad B. Anti-spasmodic action of crude methanolic extract and a new compound isolated from the aerial parts of Myrsine africana. BMC Complement Altern Med. 2011;11:55 pubmed publisher
    ..africana has antispasmodic action possibly through the calcium channel blocking mechanisms. A new compound Myrsigenin was isolated from the EtOAc fraction of the plant. ..
  5. Wang P, Wu T, Zhang Y. Monitoring and visualizing of PAHs into mangrove plant by two-photon laser confocal scanning microscopy. Mar Pollut Bull. 2012;64:1654-8 pubmed publisher
    ..05). Furthermore, without the need for sample manipulation or modification this TPLCSM provides us a real-time tool for direct observation of organic chemicals within plants. ..
  6. Hess S, Padoani C, Scorteganha L, Holzmann I, Malheiros A, Yunes R, et al. Assessment of mechanisms involved in antinociception caused by myrsinoic acid B. Biol Pharm Bull. 2010;33:209-15 pubmed
    ..These results indicate that AMB produces antinociception through mechanisms that involve interaction with L-arginine-nitric oxide, the serotonergic and cholinergic systems, as well as interaction with the alpha-adrenoceptors. ..
  7. Hao G, Hoffmann W, Scholz F, Bucci S, Meinzer F, Franco A, et al. Stem and leaf hydraulics of congeneric tree species from adjacent tropical savanna and forest ecosystems. Oecologia. 2008;155:405-15 pubmed
  8. Foubert K, Vermeersch M, Theunis M, Apers S, Cos P, Claeys M, et al. LC-MS analysis of 13,28-epoxy-oleanane saponins in Maesa spp. extracts with antileishmanial activity. Phytochem Anal. 2009;20:159-67 pubmed publisher
    ..3 and VI.2, respectively, but had a glycan part with one additional hexose residue. Several known as well as new saponins from Maesa species active against leishmaniasis were characterised using LC-MS. ..
  9. Lin W, Li L, Fu H, Sattler I, Huang X, Grabley S. New cyclopentenone derivatives from an endophytic Streptomyces sp. isolated from the mangrove plant Aegiceras comiculatum. J Antibiot (Tokyo). 2005;58:594-8 pubmed
    ..Their structures were elucidated by extensive spectroscopic (UV, IR, ESIMS, and 2D NMR) data analyses. ..
  10. Gupta A, Pereira B, Churi P. A new species of Parapanteles Ashmead (Hymenoptera: Braconidae) from India reared from Abisara echeria Stoll (Lepidoptera: Riodinidae) with key to the Indian Parapanteles species. Zootaxa. 2013;3709:363-70 pubmed
    ..nov., bred from Abisara echeria Stoll (Lepidoptera: Riodinidae) on host plant Embelia sp. (Myrsinaceae), is described and illustrated from Mumbai, Maharashtra, India...
  11. Adamu M, Naidoo V, Eloff J. Efficacy and toxicity of thirteen plant leaf acetone extracts used in ethnoveterinary medicine in South Africa on egg hatching and larval development of Haemonchus contortus. BMC Vet Res. 2013;9:38 pubmed publisher
    ..Cytotoxicity of these extracts was also evaluated using the MTT cellular assay...
  12. Li C, Zhou H, Wong Y, Tam N. Vertical distribution and anaerobic biodegradation of polycyclic aromatic hydrocarbons in mangrove sediments in Hong Kong, South China. Sci Total Environ. 2009;407:5772-9 pubmed publisher
    ..This is the first paper to report the anaerobic PAH-degrading bacteria isolated from subsurface mangrove sediment...
  13. Chang H, Lin C, Chen Y, Wang H, Chan H, Hsieh S, et al. Secondary Metabolites of the Endophytic Fungus Lachnum abnorme from Ardisia cornudentata. Int J Mol Sci. 2016;17: pubmed publisher
    ..BCRC 09F0006, derived from the endemic plant, Ardisia cornudentata Mez. (Myrsinaceae), resulted in the isolation of three new chromones, lachnochromonins D-F (1-3), one novel compound, ..
  14. Ding L, Dahse H, Hertweck C. Cytotoxic alkaloids from Fusarium incarnatum associated with the mangrove tree Aegiceras corniculatum. J Nat Prod. 2012;75:617-21 pubmed publisher
    ..Compounds 2, 4, and 5 exhibit weak antiproliferative and cytotoxic activities against HUVEC, K-562, and HeLa human cell lines, respectively. ..
  15. Baccarin T, Muceneeki R, Bresolin T, Yunes R, Malheiros A, Lucinda Silva R. Development and validation of an HPLC-PDA method for the determination of myrsinoic acid B in the extracts of Rapanea ferruginea Mez. Talanta. 2011;85:1221-4 pubmed publisher
    ..12% RSD) of the biomarker, with low intra and inter-day relative standard deviation (1.26% and 1.62%, respectively). The evaluated hydroethanolic extract and dry extract presented MAB values of 63.53 and 36.07 mg g(-1), respectively. ..
  16. Simsek O, Curuk P, Aslan F, Bayramoglu M, Izgu T, da Silva J, et al. Molecular Characterization of Cyclamen Species Collected from Different Parts of Turkey by RAPD and SRAP Markers. Biochem Genet. 2017;55:87-102 pubmed publisher
    The genus Cyclamen (family Myrsinaceae) contains about 20 species, most of which occur in the Mediterranean region. Turkey has critically important Cyclamen genetic resources...
  17. Ponnapalli M, Annam S, Ravirala S, Sukki S, Ankireddy M, Tuniki V. Unusual isomeric corniculatolides from mangrove, Aegiceras corniculatum. J Nat Prod. 2012;75:275-9 pubmed publisher
    ..The structures of the new compounds (1-4) were elucidated by a combination of spectroscopic analysis (1-5), chemical modifications, and single-crystal X-ray analysis (1). ..
  18. Guillonneau L, Taddei D, Moody C. Synthesis of the reported structure of the bisbenzoquinone lanciaquinone, isolated from Maesa lanceolata. Org Lett. 2008;10:4505-8 pubmed publisher
    ..A synthesis of the reported structure, in which the key step is a double Claisen rearrangement, suggests that the structure of the natural product needs to be revised. ..
  19. Githiori J, Hoglund J, Waller P, Baker R. Anthelmintic activity of preparations derived from Myrsine africana and Rapanea melanophloeos against the nematode parasite, Haemonchus contortus, of sheep. J Ethnopharmacol. 2002;80:187-91 pubmed
    Myrsine africana L. and Rapanea melanophloeos L. belong to the plant family Myrsinaceae. Various rural communities in Kenya, such as smallholder farmers and pastoralists, use them to treat their livestock...
  20. Cheng H, Liu Y, Tam N, Wang X, Li S, Chen G, et al. The role of radial oxygen loss and root anatomy on zinc uptake and tolerance in mangrove seedlings. Environ Pollut. 2010;158:1189-96 pubmed publisher
    ..The present study proposes new evidence of structural adaptive strategy on metal tolerance by mangrove seedlings. ..
  21. Zheng Y, Wu F. Resorcinol derivatives from Ardisia maculosa. J Asian Nat Prod Res. 2007;9:545-9 pubmed
    ..In our in vitro assay, compounds 1 and 2 showed no antimicrobial activities, however, compound 2 exhibited cytotoxity activity against human cancer cell line with GI(50) value of 2.14 x 10(- 4) mmol/ml...
  22. Sun H, Yang Y, Zhu Y, Zhang Y. In situ investigation of the depuration of fluoranthene adsorbed on the leaf surfaces of living mangrove seedlings. Talanta. 2013;116:441-7 pubmed publisher
  23. Lambert E, Geelen D. Cryopreservation of hairy root cultures from Maesa lanceolata. Commun Agric Appl Biol Sci. 2007;72:225-8 pubmed
  24. Chua L, Lee S, Abdullah N, Sarmidi M. Review on Labisia pumila (Kacip Fatimah): bioactive phytochemicals and skin collagen synthesis promoting herb. Fitoterapia. 2012;83:1322-35 pubmed publisher
    ..pumila in promoting skin collagen synthesis. The performance of the herb as anti-aging agent due to natural aging process and accelerated by UV radiation was reviewed critically. ..
  25. Li C, Yang B, Turkson J, Cao S. Anti-proliferative ambuic acid derivatives from Hawaiian endophytic fungus Pestalotiopsis sp. FT172. Phytochemistry. 2017;140:77-82 pubmed publisher
    ..All compounds were tested against A2780 and cisplatin resistant A2780 (A2780CisR) cell lines. Pestallic acid E and (+)-ambuic acid showed potent activities with IC50 values from 3.3 to 17.0 ?M. ..
  26. Zhang D, Wu J, Zhang S, Huang J. Oleanane triterpenes from Aegiceras corniculatum. Fitoterapia. 2005;76:131-3 pubmed
    ..Their structures were determined by spectroscopic methods. ..
  27. Amjad M, Arshad M, Rashid A, Chaudhari S, Malik N, Fatima S, et al. Examining relationship between environmental gradients and Lesser Himalyan forest vegetation of Nikyal valley, Azad Jammu and Kashmir using ordination analysis. Asian Pac J Trop Med. 2014;7S1:S610-6 pubmed publisher
    ..These results indicate a deteriorated forest structure and reduced regeneration pattern, demanding immediate attention of forest management authorities. ..
  28. Lin Z, Lu Z, Zhu T, Fang Y, Gu Q, Zhu W. Penicillenols from Penicillium sp. GQ-7, an endophytic fungus associated with Aegiceras corniculatum. Chem Pharm Bull (Tokyo). 2008;56:217-21 pubmed
    ..Penicillenols A(1) and B(1) showed cytotoxicities against HL-60 cell line with IC(50) values of 0.76 microM and 3.20 microM, respectively...
  29. Mishra S, Das A. Effect of NaCl on leaf salt secretion and antioxidative enzyme level in roots of a mangrove, Aegiceras corniculatum. Indian J Exp Biol. 2003;41:160-6 pubmed
    ..It was concluded that loss of activities of antioxidative enzymes at high salt treatment, caused leaf senescence in spite of high rates of salt secretion by Aegiceras corniculatum...
  30. Wei L, Yan C, Wu G, Guo X, Ye B. Variation of delta13C in Aegiceras corniculatum seedling induced by cadmium application. Ecotoxicology. 2008;17:480-4 pubmed publisher
    ..78 mg/kg which was not expected to exist in natural environments. Minor variation in delta13C values observed in roots and leaves was likely due to limited Cd uptake by seedlings and subsequent lack of negative impacts on photosynthesis...
  31. Zhang G, Sun S, Zhu T, Lin Z, Gu J, Li D, et al. Antiviral isoindolone derivatives from an endophytic fungus Emericella sp. associated with Aegiceras corniculatum. Phytochemistry. 2011;72:1436-42 pubmed publisher
    ..Their structures were elucidated on the basis of NMR spectroscopic evidence while the anti-influenza A viral (H?N?) activities of eight compounds were also evaluated using the cytopathic effect (CPE) inhibition assay...
  32. Ito S, Narise A, Shimura S. Identification of a methioninase inhibitor, myrsinoic acid B, from Myrsine seguinii Lév., and its inhibitory activities. Biosci Biotechnol Biochem. 2008;72:2411-4 pubmed
    ..The IC50 values were 10.5, 82.4, and 30.3 microM respectively...
  33. Sahu B, Anubolu H, Koneru M, Kumar J, Kuncha M, Rachamalla S, et al. Cardioprotective effect of embelin on isoproterenol-induced myocardial injury in rats: possible involvement of mitochondrial dysfunction and apoptosis. Life Sci. 2014;107:59-67 pubmed publisher
    ..This study investigated the cardioprotective effect and possible mechanism of embelin, a major constituent of Embelia ribes Burm, using isoproterenol (ISO)-induced myocardial infarction model in rats...
  34. Wu Q, Leung J, Tam N, Peng Y, Guo P, Zhou S, et al. Contamination and distribution of heavy metals, polybrominated diphenyl ethers and alternative halogenated flame retardants in a pristine mangrove. Mar Pollut Bull. 2016;103:344-348 pubmed publisher
    ..The findings imply that tidal flushing was an important pollution source, while mangrove plants have the capacity to minimize the impact of heavy metals, but not PBDEs and AHFRs. ..
  35. Xu M, Cui J, Fu H, Proksch P, Lin W, Li M. Embelin derivatives and their anticancer activity through microtubule disassembly. Planta Med. 2005;71:944-8 pubmed
    ..Treatment with 10 microM of 1 and 2 for 24 h induced apoptosis in HL-60 cells. This evidence suggests that both 1 and 2 are promising novel antimitotic and anticancer molecules targeting microtubular proteins...
  36. Ye Y, Tam N. Effects of used lubricating oil on two mangroves Aegiceras corniculatum and Avicennia marina. J Environ Sci (China). 2007;19:1355-60 pubmed
    ..For both species, oil pollution significantly reduced leaf, root, and total biomass, but did not significantly affect stem biomass. Oil pollution resulted in damage to the xylem vessels of fine roots but not to those of mediate roots...
  37. Matsunami K, Otsuka H, Takeda Y. Myrseguinosides A-E, five new glycosides from the fruits of Myrsine seguinii. Chem Pharm Bull (Tokyo). 2011;59:1274-80 pubmed
    Chemical investigation of the 1-BuOH soluble fraction of the dried fruits of Myrsine seguinii (Myrsinaceae) led to the isolation of five new glycosides, named myrseguinosides A-E (1-5), together with eight known compounds (6-13)...
  38. Wang F, Xu M, Li Q, Sattler I, Lin W. p-Aminoacetophenonic acids produced by a mangrove endophyte Streptomyces sp. (strain HK10552). Molecules. 2010;15:2782-90 pubmed publisher
    ..In the bioassay test, 1-4 showed no cytotoxicity against the Hela cell lines. Compound 4 also showed no inhibitory bioactivity on HCV protease and SecA ATPase and wasn't active against VSVG/HIV-luc pseudotyping virus...
  39. Li Y, Li Q, Zhou K, Sun X, Zhao L, Zhang Y. Occurrence and distribution of the environmental pollutant antibiotics in Gaoqiao mangrove area, China. Chemosphere. 2016;147:25-35 pubmed publisher
    ..Principal components analysis revealed that the terrestrial input and different habitats directly influenced the occurrence and distribution of antibiotics. ..
  40. Melville F, Pulkownik A. Investigation of mangrove macroalgae as bioindicators of estuarine contamination. Mar Pollut Bull. 2006;52:1260-9 pubmed
    ..This species showed strong potential for use as a bioindicator of estuarine contamination...
  41. Gielens C, Idakieva K, De Maeyer M, Van den Bergh V, Siddiqui N, Compernolle F. Conformational stabilization at the active site of molluskan (Rapana thomasiana) hemocyanin by a cysteine-histidine thioether bridge A study by mass spectrometry and molecular modeling. Peptides. 2007;28:790-7 pubmed
    ..It is suggested that the role of the bridge is to fix the histidine in an orientation that is optimal for coordination of the Cu(A) atom...
  42. Liu Y, Li F, Huang Q. Allelopathic effects of gallic acid from Aegiceras corniculatum on Cyclotella caspia. J Environ Sci (China). 2013;25:776-84 pubmed
    ..Our results could provide preliminary and valuable reference on the complex influences of mangroves on microecology and microbial communities in the rhizosphere system...
  43. Manns U, Anderberg A. Relationships of Anagallis foemina and A. arvensis (Myrsinaceae): new insights inferred from DNA sequence data. Mol Phylogenet Evol. 2007;45:971-80 pubmed
    ..arvensis individuals shared the second haplotype. Ancestral cpDNA polymorphism within Anagallis arvensis or hybridization are possible explanations, however, information in ITS data is too scarce to falsify any of these hypotheses...
  44. Massa A, Wanjugi H, Deal K, O brien K, You F, Maiti R, et al. Gene space dynamics during the evolution of Aegilops tauschii, Brachypodium distachyon, Oryza sativa, and Sorghum bicolor genomes. Mol Biol Evol. 2011;28:2537-47 pubmed publisher
  45. Elisha I, Botha F, McGaw L, Eloff J. The antibacterial activity of extracts of nine plant species with good activity against Escherichia coli against five other bacteria and cytotoxicity of extracts. BMC Complement Altern Med. 2017;17:133 pubmed publisher
    ..Further investigation is in progress on C. triflora and H. roeperianum, both of which had promising activities and potential safety based on cytotoxicity. ..
  46. Theunis M, Foubert K, Pollier J, Gonzalez Guzman M, Goossens A, Vlietinck A, et al. Determination of saponins in Maesa lanceolata by LC-UV: development and validation. Phytochemistry. 2007;68:2825-30 pubmed
    ..8-140.0mug/mL. The recovery from the leaves was 94.5%. The precision of the method with respect to time and concentration was acceptable, with relative standard deviation (RSD%) values of 4.9 and 4.3, respectively...
  47. Xu M, Deng Z, Li M, Li J, Fu H, Proksch P, et al. Chemical constituents from the mangrove plant, Aegiceras corniculatum. J Nat Prod. 2004;67:762-6 pubmed
    ..The structures of 1-7 were determined by spectroscopic methods. Compound 2 and 5-O-methylembelin showed in vitro cytotoxicity against the HL-60, Bel(7402), U937, and Hela cell lines...
  48. Tam N, Wong Y. Effectiveness of bacterial inoculum and mangrove plants on remediation of sediment contaminated with polycyclic aromatic hydrocarbons. Mar Pollut Bull. 2008;57:716-26 pubmed publisher
    ..These results demonstrated that the mangrove sediment itself had sufficient indigenous microorganisms capable of naturally remedying PAH contamination...
  49. Idakieva K, Siddiqui N, Meersman F, De Maeyer M, Chakarska I, Gielens C. Influence of limited proteolysis, detergent treatment and lyophilization on the phenoloxidase activity of Rapana thomasiana hemocyanin. Int J Biol Macromol. 2009;45:181-7 pubmed publisher
    ..The low level of intrinsic PO activity in the investigated hemocyanin is related to the inaccessibility of the binuclear copper active sites to the substrates...
  50. Medeiros A, Berois N, Incerti M, Bay S, Franco Fraguas L, Osinaga E. A Tn antigen binding lectin from Myrsine coriacea displays toxicity in human cancer cell lines. J Nat Med. 2013;67:247-54 pubmed publisher
    ..McL could be exploited in the design of potential new tools for the diagnosis or treatment of cancer...
  51. Liao B, Li M, Zheng S, Chen Y, Zhong C, Huang Z. [Niches of several mangrove species in Dongzhai Harbor of Hainan Island]. Ying Yong Sheng Tai Xue Bao. 2005;16:403-7 pubmed
    ..apetala with S. caseolaris, A. corniculatum, K. candel and A. marina, S. apetala with R. stylosa and B. sexangula, S. apetala with C. tagal, and S. apetala with B. sexangula...
  52. Ding L, Peschel G, Hertweck C. Biosynthesis of archetypal plant self-defensive oxylipins by an endophytic fungus residing in mangrove embryos. Chembiochem. 2012;13:2661-4 pubmed publisher
    ..Stable-isotope labeling experiments revealed that the endophyte biosynthesizes coriolic acid, didehydrocoriolic acid, and an epoxy fatty acid derived from linoleic acid by a process involving ?(15)-desaturation and 13-lipoxygenation...
  53. Guangqiu Q, Chongling Y, Haoliang L. Influence of heavy metals on the carbohydrate and phenolics in mangrove, Aegiceras corniculatum L., seedlings. Bull Environ Contam Toxicol. 2007;78:440-4 pubmed
  54. Li L, Ding Y, Groth I, Menzel K, Peschel G, Voigt K, et al. Pyrrole and indole alkaloids from an endophytic Fusarium incarnatum (HKI00504) isolated from the mangrove plant Aegiceras corniculatum. J Asian Nat Prod Res. 2008;10:775-80 pubmed publisher
    ..The structures of compounds 1-3 were determined on the basis of extensive spectroscopic data analyses...
  55. Pollier J, Gonzalez Guzman M, Ardiles Diaz W, Geelen D, Goossens A. An integrated PCR colony hybridization approach to screen cDNA libraries for full-length coding sequences. PLoS ONE. 2011;6:e24978 pubmed publisher
    ..However, most of the gene tags do not correspond to full-length (FL) coding sequences, which is a prerequisite for subsequent functional analysis...
  56. Fazliana M, Wan Nazaimoon W, Gu H, Ostenson C. Labisia pumila extract regulates body weight and adipokines in ovariectomized rats. Maturitas. 2009;62:91-7 pubmed publisher
    ..alata (LPva), and compared to estrogen replacement (ERT), on body weight gain, uterus weight, adipose tissue mRNA and protein levels of adipokines in ovariectomized (OVX) rats...
  57. Zheng C, Ji D, Liu W, Qiu J, Wu J, Chen S, et al. [Eco-physiological responses of high-latitude transplanted Aegiceras corniculatum seedlings to NaCl stress]. Ying Yong Sheng Tai Xue Bao. 2011;22:2279-84 pubmed
    ..corniculatum vegetative organs was maladjusted, which inhibited the normal growth of the seedlings, resulting in a significant decrease in the plant height and fresh and dry mass...
  58. de Mejia E, Ramirez Mares M. Leaf extract from Ardisia compressa protects against 1-nitropyrene-induced cytotoxicity and its antioxidant defense disruption in cultured rat hepatocytes. Toxicology. 2002;179:151-62 pubmed
    ..005), as well as the cellular level of GSH. The results indicate that AC has an antioxidant protective effect on rat hepatocytes when exposed to 1-NP...
  59. Sundaram R, Ganesan R, Murugesan G. In vitro antiplasmodial activity of spiro benzofuran compound from mangrove plant of Southern India. Asian Pac J Trop Med. 2012;5:358-61 pubmed publisher
    ..It is concluded from the present study that, the chemical constituents of A. corniculatum collected from Pichavaram mangrove forest can be used as a putative antiplasmodial drugs in future. ..
  60. Mehrbod P, Abdalla M, Njoya E, Ahmed A, Fotouhi F, Farahmand B, et al. South African medicinal plant extracts active against influenza A virus. BMC Complement Altern Med. 2018;18:112 pubmed publisher
    ..However, Tabernaemontana ventricosa, Cussonia spicata and Clerodendrum glabrum leaf extracts were ineffective in vitro in this study. ..
  61. Pandey A, Bani S, Sangwan P, Koul S. Selective Th1 upregulation by ethyl acetate fraction of Labisia pumila. J Ethnopharmacol. 2010;132:309-15 pubmed publisher
  62. Van Twembeke E, Geelen D. Micropropagation of the medicinal plant Maesa lanceolata Forssk. Commun Agric Appl Biol Sci. 2006;71:311-3 pubmed
  63. Roome T, Dar A, Ali S, Naqvi S, Choudhary M. A study on antioxidant, free radical scavenging, anti-inflammatory and hepatoprotective actions of Aegiceras corniculatum (stem) extracts. J Ethnopharmacol. 2008;118:514-21 pubmed publisher
    ..The present study was conducted to evaluate the antioxidant, anti-inflammatory and hepatoprotective potential of Aegiceras corniculatum Linn. Blanco (Aegicerataceae)...
  64. Kumar G K, Dhamotharan R -, Kulkarni N, Honnegowda S, Murugesan S -. Embelin ameliorates dextran sodium sulfate-induced colitis in mice. Int Immunopharmacol. 2011;11:724-31 pubmed publisher
  65. Li F, Tuo L, Pan Z, Guo M, Lee S, Chen L, et al. Aureimonas endophytica sp. nov., a novel endophytic bacterium isolated from Aegiceras corniculatum. Int J Syst Evol Microbiol. 2017;67:2934-2940 pubmed publisher
    ..nov. is proposed. The type strain of Aureimonas endophytica sp. nov. is 2T4P-2-4T (=KCTC 52217T=CGMCC 1.15367T)...
  66. Nakahashi C, Frole K, Sack L. Bacterial leaf nodule symbiosis in Ardisia (Myrsinaceae): does it contribute to seedling growth capacity?. Plant Biol (Stuttg). 2005;7:495-500 pubmed
    Numerous species of Ardisia (shrubs in the Myrsinaceae) possess conspicuous bacterial nodules in their leaf margins...
  67. Primavera J. Global voices of science: Mangroves, fishponds, and the quest for sustainability. Science. 2005;310:57-9 pubmed
    ..With an eye on all stakeholders, Primavera lays out how aquaculture is now falling short of the goal of sustainability and what steps might be taken to move the industry in that direction...
  68. Melville F, Pulkownik A. Investigation of mangrove macroalgae as biomonitors of estuarine metal contamination. Sci Total Environ. 2007;387:301-9 pubmed
    ..The uptake of metals also varied among the different species, suggesting that algal parameters, such as morphology, may also influence metal uptake and accumulation...
  69. Faizal A, Geelen D. Agroinfiltration of intact leaves as a method for the transient and stable transformation of saponin producing Maesa lanceolata. Plant Cell Rep. 2012;31:1517-26 pubmed publisher
    ..This transformation protocol will be used to introduce overexpression and RNAi constructs into M. lanceolata plants that may interfere with triterpenoid saponin biosynthesis...
  70. Al Mekhlafi N, Shaari K, Abas F, Kneer R, Jeyaraj E, Stanslas J, et al. Alkenylresorcinols and cytotoxic activity of the constituents isolated from Labisia pumila. Phytochemistry. 2012;80:42-9 pubmed publisher
    Phytochemical investigation on the leaves of Labisia pumila (Myrsinaceae), an important medicinal herb in Malaysia, has led to the isolation of 1-O-methyl-6-acetoxy-5-(pentadec-10Z-enyl)resorcinol (1), labisiaquinone A (2) and ..
  71. Manguro L, Lemmen P, Hao P, Wong K. Triterpene saponins of Maesa lanceolata stem wood. J Asian Nat Prod Res. 2012;14:987-1001 pubmed publisher
    ..1 to 14 ± 0.2 mm were observed. Among the isolates, compound 1 was the most active with an minimum inhibitory concentration value of 25 ?g/ml against Staphylococcus aureus...
  72. Roome T, Dar A, Naqvi S, Ali S, Choudhary M. Aegiceras corniculatum extract suppresses initial and late phases of inflammation in rat paw and attenuates the production of eicosanoids in rat neutrophils and human platelets. J Ethnopharmacol. 2008;120:248-54 pubmed publisher
    ..Blanco stems extracts and their mechanism of action against various pro-inflammatory mediators and to validate its traditional use against inflammatory diseases...
  73. Sumino M, Sekine T, Ruangrungsi N, Ikegami F. Ardisiphenols A-C, novel antioxidants from the fruits of Ardisia colorata. Chem Pharm Bull (Tokyo). 2001;49:1664-5 pubmed
    ..Their structures were determined by the NMR and MS/MS analyses. All compounds showed scavenging activities towards 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and cytotoxicities against murine breast cancer cell line, FM3A...
  74. Okemo P, Bais H, Vivanco J. In vitro activities of Maesa lanceolata extracts against fungal plant pathogens. Fitoterapia. 2003;74:312-6 pubmed
    ..Fusarium oxysporium, Pythium ultimum, Cochliobolus heterostrophus, Rhizoctonia solani, Sclerotium rolfsii and Pyrenophora teres. M. lanceolata extracts were very active against all the pathogens tested except P. ultimum and R. solani...
  75. Apers S, Everaert G, van der Veken B, Vlietinck A, Pieters L. Electronic structure calculations as a tool for investigating acyl migrations in ester saponins. Phytochem Anal. 2002;13:262-5 pubmed
    ..It was confirmed that acyl migrations could occur in rings D and E of maesasaponins...
  76. Ravikumar S, Ramanathan G, Inbaneson S, Ramu A. Antiplasmodial activity of two marine polyherbal preparations from Chaetomorpha antennina and Aegiceras corniculatum against Plasmodium falciparum. Parasitol Res. 2011;108:107-13 pubmed publisher
    ..57?±?0.465%) against Plasmodium berghei at 120 mg kg?¹ bw. This study shows that combinations of mangrove plants and seaweeds extracts had a source of lead compounds for the development of new drugs for the treatment of malaria...
  77. Schlindwein C, Fett Neto A, Dillenburg L. Chemical and mechanical changes during leaf expansion of four woody species of dry Restinga woodland. Plant Biol (Stuttg). 2006;8:430-8 pubmed
    ..umbellata seems to invest more on mechanical defences, even at early stages of leaf growth, as well as on a low allocation of nitrogen to the leaves. The other species display intermediate characteristics...
  78. Chen G, Ye Y, Lu C, Li R, Weng J, Xu Y. [Distribution of Littoraia melanostoma Gray (Littorinidae) and Nerita lineata Gmelin (Neritadae) in rehabilitated mangroves]. Ying Yong Sheng Tai Xue Bao. 2006;17:1721-5 pubmed
    ..lineate had a strong inhabitation preference for mature K. candel forest, while L. melanostoma was apt to inhabit in younger A. corniculatum forests...
  79. Foubert K, Breynaert A, Theunis M, Van Den Bossche R, De Meyer G, Van Daele A, et al. Evaluation of the anti-angiogenic activity of saponins from Maesa lanceolata by different assays. Nat Prod Commun. 2012;7:1149-54 pubmed
    ..The use of different test systems, however, implies different results in the case of saponins...
  80. Bagalwa M, Chifundera K. Environmental impact evaluation of the stem bark extract of Maesa lanceolata used in Democratic Republic of Congo. J Ethnopharmacol. 2007;114:281-4 pubmed
    ..On this point of view, the safety tests of extract from Maesa lanceolata (Myrsinaceae) candidate for snails control in the Democratic Republic of Congo, were undertaken...
  81. Rajput V, Mukhopadhyay B. Concise synthesis of a pentasaccharide related to the anti-leishmanial triterpenoid saponin isolated from Maesa balansae. J Org Chem. 2008;73:6924-7 pubmed publisher
    ..H2SO4-silica was proved to be a better choice as promoter than conventional Lewis acid promoters such as TfOH or TMSOTf...
  82. Mannerås L, Fazliana M, Wan Nazaimoon W, Lönn M, Gu H, Ostenson C, et al. Beneficial metabolic effects of the Malaysian herb Labisia pumila var. alata in a rat model of polycystic ovary syndrome. J Ethnopharmacol. 2010;127:346-51 pubmed publisher
    ..In this study, we investigated the effect of LPva on body composition and metabolic features in female rats treated continuously with dihydrotestosterone, starting before puberty, to induce PCOS...
  83. Karimi E, Jaafar H, Ghasemzadeh A, Ebrahimi M. Fatty acid composition, antioxidant and antibacterial properties of the microwave aqueous extract of three varieties of Labisia pumila Benth. Biol Res. 2015;48:9 pubmed publisher
    ..The present study was conducted in order to evaluate the fatty acid profile, anti-oxidant and anti-bacterial activities from the microwave aqueous extract of the leaves of three different varieties of Labisia pumila Benth...
  84. Novaes P, Imatomi M, Varela R, Molinillo J, Lacret R, Gualtieri S, et al. Allelopathic potential of Rapanea umbellata leaf extracts. Chem Biodivers. 2013;10:1539-48 pubmed publisher
    ..Finally, the general bioactivity of the two compounds was studied, which indicated that the presence of 1 might be part of the defense mechanisms of this plant. ..
  85. Yang L, Khoo Beattie C, Goh K, Chng B, Yoganathan K, Lai Y, et al. Ardisiaquinones from Ardisia teysmanniana. Phytochemistry. 2001;58:1235-8 pubmed
    Bioassay-guided fractionation of a CHCl(3) extract from the leaves of Ardisia teysmanniana Scheff. (Myrsinaceae) has led to the isolation of three new alkyldibenzoquinone derivatives that showed inhibitory activity in an in vitro assay ..