melia azedarach

Summary

Summary: A plant species of the genus MELIA, family MELIACEAE, which is toxic to insects. The name is very similar to Melia azadirachta (AZADIRACHTA).

Top Publications

  1. Carpinella C, Ferrayoli C, Valladares G, Defago M, Palacios S. Potent limonoid insect antifeedant from Melia azedarach. Biosci Biotechnol Biochem. 2002;66:1731-6 pubmed
    Systematic fractionation of a fruit extract from Argentine Melia azedarach L...
  2. Zhou H, Hamazaki A, Fontana J, Takahashi H, Wandscheer C, Fukuyama Y. Cytotoxic limonoids from Brazilian Melia azedarach. Chem Pharm Bull (Tokyo). 2005;53:1362-5 pubmed
    ..1-3) and one new tetracyclic limonoid (4) were isolated from a methanol extract of the ripe fruits of Melia azedarach collected in Curitiba, Brazil, and their structures were elucidated by spectroscopic data analysis and ..
  3. Roop J, Dhaliwal P, Guraya S. Extracts of Azadirachta indica and Melia azedarach seeds inhibit folliculogenesis in albino rats. Braz J Med Biol Res. 2005;38:943-7 pubmed
    ..indica seed extract at 3 and 6 mg kg body weight-1 day-1 and Melia azedarach Linn. (dharek) seed extract at 24 mg kg body weight-1 day-1 for 18 days...
  4. Saikia A, Ryakala V, Sharma P, Goswami P, Bora U. Ethnobotany of medicinal plants used by Assamese people for various skin ailments and cosmetics. J Ethnopharmacol. 2006;106:149-57 pubmed
    ..Herbal remedies were also available for skin burns, prickly heat and pimples. Information on nine plants used for managing dry skin also emerged from this study...
  5. Andrade Coelho C, Souza N, Gouveia C, Silva V, Gonzalez M, Rangel E. Effect of fruit and leaves of Meliaceae plants (Azadirachta indica and Melia azedarach) on the development of Lutzomyia longipalpis larvae (Diptera: Psychodidae: Phlebotominae) under experimental conditions. J Med Entomol. 2009;46:1125-30 pubmed
    ..on the feeding of dried, ground, homogeneous powdered, unprocessed fruit and leaves of Azadirachta indica and Melia azedarach to Lutzomyia longipalpis larvae to determine the effects on their mortality and metamorphosis. A...
  6. Phua D, Tsai W, Ger J, Deng J, Yang C. Human Melia azedarach poisoning. Clin Toxicol (Phila). 2008;46:1067-70 pubmed publisher
    In traditional Chinese medicine, Melia azedarach (Ku-lian) is used orally and topically as an antiparasitic and antifungal agent...
  7. Petrera E, Coto C. Effect of meliacine, a plant derived antiviral, on tumor necrosis factor alpha. Fitoterapia. 2003;74:77-83 pubmed
    ..Meliacine alone, at a concentration of 56 microg/ml, is a weak inducer of TNF-alpha production...
  8. Vila S, Gonzalez A, Rey H, Mroginski L. Effect of morphological heterogeneity of somatic embryos of Melia azedarach on conversion into plants. Biocell. 2010;34:7-13 pubmed
    Embryogenic cultures were initiated from immature Melia azedarach (Meliaceae) zigotic embryos. Explants were induced on Murashige and Skoog (1962) medium with 4.54 microM thidiazuron or 0.45 microM dichlorophenoxyacetic acid...
  9. Maciel M, Morais S, Bevilaqua C, Camurça Vasconcelos A, Costa C, Castro C. Ovicidal and larvicidal activity of Melia azedarach extracts on Haemonchus contortus. Vet Parasitol. 2006;140:98-104 pubmed
    ..In the search for natural anthelmintics, Melia azedarach L...

More Information

Publications88

  1. Liu H, Zhang C, Dong S, Dong L, Wu Y, Yue J. Limonoids and triterpenoids from the seeds of Melia azedarach. Chem Pharm Bull (Tokyo). 2011;59:1003-7 pubmed
    ..1-3), and two triterpenes (4) and (5), along with twelve known compounds, were isolated from the seeds of Melia azedarach. Their structures were established on the basis of extensive spectroscopic analysis...
  2. Li X, Zhang Q, Zhang A, Gao J. Metabolites from Aspergillus fumigatus, an endophytic fungus associated with Melia azedarach, and their antifungal, antifeedant, and toxic activities. J Agric Food Chem. 2012;60:3424-31 pubmed publisher
    ..the fermentation broth of Aspergillus fumigatus LN-4, an endophytic fungus isolated from the stem bark of Melia azedarach. Their structures were elucidated on the basis of detailed spectroscopic analysis (mass spectrometry and one- ..
  3. Carpinella M, Ferrayoli C, Palacios S. Antifungal synergistic effect of scopoletin, a hydroxycoumarin isolated from Melia azedarach L. fruits. J Agric Food Chem. 2005;53:2922-7 pubmed
    ..for antifungal compounds from plants, the hydroxycoumarin scopoletin (1) was isolated from seed kernels of Melia azedarach L...
  4. Charleston D, Kfir R, Vet L, Dicke M. Behavioural responses of diamondback moth Plutella xylostella (Lepidoptera: Plutellidae) to extracts derived from Melia azedarach and Azadirachta indica. Bull Entomol Res. 2005;95:457-65 pubmed
    The impact of three different doses of botanical insecticide derived from the syringa tree, Melia azedarach and the neem tree, Azadirachta indica was tested on the behaviour of the diamondback moth, Plutella xylostella (Linnaeus)...
  5. Tan Q, Li X, Chen H, Feng T, Cai X, Luo X. Sterols and terpenoids from Melia azedarach. J Nat Prod. 2010;73:693-7 pubmed publisher
    ..A-seco natural product (1), five new terpenoids (4-8), and 15 known compounds were isolated from the bark of Melia azedarach. Their structures were elucidated by means of spectroscopic data, and the structure of 1 was confirmed by X-..
  6. Fill T, da Silva B, Rodrigues Fo E. Biosynthesis of phenylpropanoid amides by an endophytic Penicillium brasilianum found in root bark of Melia azedarach. J Microbiol Biotechnol. 2010;20:622-9 pubmed
    ..potently convulsive and bacteriostatic compounds from an endophytic Penicillium brasilianum isolated from Melia azedarach (Meliaceae), confirms their phenylpropanoid origin, which is very uncommon in fungi...
  7. Jabeen K, Javaid A, Ahmad E, Athar M. Antifungal compounds from Melia azedarach leaves for management of Ascochyta rabiei, the cause of chickpea blight. Nat Prod Res. 2011;25:264-76 pubmed publisher
    The antifungal activity of Melia azedarach L. leaves was investigated against Ascochyta rabiei (Pass.) Lab., the cause of destructive blight disease of chickpea (Cicer arietinum L.)...
  8. Fukuyama Y, Nakaoka M, Yamamoto T, Takahashi H, Minami H. Degraded and oxetane-bearing limonoids from the roots of Melia azedarach. Chem Pharm Bull (Tokyo). 2006;54:1219-22 pubmed
    Brine shrimp lethality test (BST)-guided fractionation of a methanol extract of the roots of Melia azedarach resulted in the isolation of two new limonoids, 9alpha-hydroxy-12alpha-acetoxyfraxinellone (1) and 7,14-epoxy-azedarachin B (2), ..
  9. Bullangpoti V, Wajnberg E, Audant P, Feyereisen R. Antifeedant activity of Jatropha gossypifolia and Melia azedarach senescent leaf extracts on Spodoptera frugiperda (Lepidoptera: Noctuidae) and their potential use as synergists. Pest Manag Sci. 2012;68:1255-64 pubmed publisher
    ..study has been made of the toxicity of ethanolic senescent leaf extracts (SLEs) of Jatropha gossypifolia and Melia azedarach on larvae of the noctuid pest Spodoptera frugiperda...
  10. Wandscheer C, Duque J, da Silva M, Fukuyama Y, Wohlke J, Adelmann J, et al. Larvicidal action of ethanolic extracts from fruit endocarps of Melia azedarach and Azadirachta indica against the dengue mosquito Aedes aegypti. Toxicon. 2004;44:829-35 pubmed
    Ethanolic extracts from the kernels of ripe fruits from the Indian Lilac Melia azedarach and from the well-known Neem tree, Azadirachta indica were assayed against larvae of Aedes aegypti, the mosquito vector of dengue fever...
  11. Borges L, Ferri P, Silva W, Silva W, Silva J. In vitro efficacy of extracts of Melia azedarach against the tick Boophilus microplus. Med Vet Entomol. 2003;17:228-31 pubmed
    The efficacy of ripe fruit extracts of Melia azedarach L. (Rutales: Meliaceae) was evaluated against the tick, Boophilus microplus (Canestrini) (Acari: Ixodidae). Ripe fruits of M...
  12. Carpinella M, Miranda M, Almirón W, Ferrayoli C, Almeida F, Palacios S. In vitro pediculicidal and ovicidal activity of an extract and oil from fruits of Melia azedarach L. J Am Acad Dermatol. 2007;56:250-6 pubmed
    ..Head louse infestation is difficult to control because of increasing lice resistance to synthetic pediculicidal drugs...
  13. Wu S, Bao Q, Wang W, Zhao Y, Xia G, Zhao Z, et al. Cytotoxic triterpenoids and steroids from the bark of Melia azedarach. Planta Med. 2011;77:922-8 pubmed publisher
    ..and two new steroids (3, 4) along with twelve related known compounds (5-16) were isolated from the bark of Melia azedarach. The new structures were elucidated by means of spectroscopic methods and molecular modeling studies and ..
  14. Asnake S, Teklehaymanot T, Hymete A, Erko B, Giday M. Evaluation of the antiplasmodial properties of selected plants in southern Ethiopia. BMC Complement Altern Med. 2015;15:448 pubmed publisher
    ..to evaluate the safety and antimalarial activity of extracts of Ajuga integrifolia, Clerodendrum myricoides, Melia azedarach, Peponium vogelii and Premna schimperi, locally used by the Sidama people of Ethiopia to treat malaria...
  15. Wu S, Ji Y, Zhu J, Zhao Y, Xia G, Hu Y, et al. Steroids from the leaves of Chinese Melia azedarach and their cytotoxic effects on human cancer cell lines. Steroids. 2009;74:761-5 pubmed publisher
    Three new (1-3) and several known (4-6) steroids were isolated from the leaves of Chinese Melia azedarach. The structures of the new compounds were elucidated by means of spectroscopic methods including 2D NMR techniques and mass ..
  16. Forim M, Cornélio V, da Silva M, Rodrigues Filho E, Fernandes J, Vieira P, et al. Chemical characterization of Azadirachta indica grafted on Melia azedarach and analyses of azadirachtin by HPLC-MS-MS (SRM) and meliatoxins by MALDI-MS. Phytochem Anal. 2010;21:363-73 pubmed publisher
    b>Melia azedarach adapted to cool climates was selected as rootstocks for vegetative propagation of Azadirachta indica. Cleft grafting of A. indica on M. azedarach rootstock showed excellent survival...
  17. Alerico G, Beckenkamp A, Vignoli Silva M, Buffon A, von Poser G. Proliferative effect of plants used for wound healing in Rio Grande do Sul state, Brazil. J Ethnopharmacol. 2015;176:305-10 pubmed publisher
    ..Aqueous extracts from Achyrocline satureioides DC Lam., Matricaria recutita L., Melia azedarach L. and Mirabilis jalapa L...
  18. Kang W, Bao J, Zheng J, Xu F, Wang L. Potential of woody plants from a Tonglushan ancient copper spoil heap for phytoremediation of heavy metal contaminated soil1. Int J Phytoremediation. 2016;: pubmed
    ..Broussonetia papyrifera, Ligutrums lucidum, Viburnum awabuk, Firminan simplex, Robina pseudoacacial, Melia azedarach and Osmanthus fragrans exhibited high accumulated capacity and strong tolerance to heavy metals...
  19. Chang H, Guo J, Fu X, Liu Y, Wyckhuys K, Hou Y, et al. Molecular-Assisted Pollen Grain Analysis Reveals Spatiotemporal Origin of Long-Distance Migrants of a Noctuid Moth. Int J Mol Sci. 2018;19: pubmed publisher
    ..europaea, Ligustrum lucidum, Robinia pseudoacacia, Castanopsis echinocarpa, Melia azedarach and Castanea henryi. As the above plants are indigenous to southern climes, we deduce that A...
  20. Yanes A, Finol H, Hasegawa M. Effects of Azadirachta indica and Melia azedarach (Meliaceae) extracts from leaves on Trypanosoma cruzi growth and ultrastructure. J Submicrosc Cytol Pathol. 2004;36:149-54 pubmed
    The chloroformic extracts from dried fresh leaves ofAzadirachta indica A. Juss. and Melia azedarach L...
  21. Khalid M, Hassani D, Bilal M, Butt Z, Hamayun M, Ahmad A, et al. Identification of oral cavity biofilm forming bacteria and determination of their growth inhibition by Acacia arabica, Tamarix aphylla L. and Melia azedarach L. medicinal plants. Arch Oral Biol. 2017;81:175-185 pubmed publisher
  22. Carpinella M, Giorda L, Ferrayoli C, Palacios S. Antifungal effects of different organic extracts from Melia azedarach L. on phytopathogenic fungi and their isolated active components. J Agric Food Chem. 2003;51:2506-11 pubmed
    Extracts from different parts of Melia azedarach L. were studied as potential antifungal agents for selected phytopathogenic fungi...
  23. Jhou H, Wang Y, Wu C, Yu J, Chen C. Photosynthetic gas exchange responses of Swietenia macrophylla King and Melia azedarach L. plantations under drought conditions. Bot Stud. 2017;58:57 pubmed publisher
    ..Swietenia macrophylla King and Melia azedarach L. are economically valuable trees that are widely planted in southern Taiwan...
  24. Haramboure M, Mirande L, Smagghe G, Pineda S, Schneider M. Compatibility of a Melia azedarach extract with Eriopis connexa (Coleoptera: Coccinellidae). Commun Agric Appl Biol Sci. 2010;75:373-8 pubmed
    ..The Chinaberry tree, Melia azedarach L...
  25. Joray M, Villafañez F, González M, Crespo M, Laiolo J, Palacios S, et al. P53 tumor suppressor is required for efficient execution of the death program following treatment with a cytotoxic limonoid obtained from Melia azedarach. Food Chem Toxicol. 2017;109:888-897 pubmed publisher
    ..Taken together, these findings position 1 as a potent antitumor agent, with potential for the development of novel chemotherapeutic drugs based on the induction of S-phase arrest. ..
  26. Ntalli N, Cottiglia F, Bueno C, Alché L, Leonti M, Vargiu S, et al. Cytotoxic tirucallane triterpenoids from Melia azedarach fruits. Molecules. 2010;15:5866-77 pubmed publisher
    ..investigation of the dichloromethane-soluble part of the methanol extract obtained from the fruits of Melia azedarach afforded one new tirucallane-type triterpene, 3-alpha-tigloylmelianol and three known tirucallanes, melianone,..
  27. Deng Z, Yuan T, Cui S, Liu S, Xie Y, Yao Q. Development and validation of an LC-MS-MS method for determination of methyl kulonate in rat plasma. Biomed Chromatogr. 2012;26:857-62 pubmed
    ..This pharmacokinetic study of methyl kulonate is reported here for the first time. ..
  28. Moreno Castilla C, García Rosero H, Carrasco Marín F. Symmetric Supercapacitor Electrodes from KOH Activation of Pristine, Carbonized, and Hydrothermally Treated Melia azedarach Stones. Materials (Basel). 2017;10: pubmed publisher
    ..In this study, we investigated the potential use of Melia azedarach (MA) stones to prepare ACs for supercapacitors. The ash content was considerably lower in MA stones (0...
  29. Akihisa T, Pan X, Nakamura Y, Kikuchi T, Takahashi N, Matsumoto M, et al. Limonoids from the fruits of Melia azedarach and their cytotoxic activities. Phytochemistry. 2013;89:59-70 pubmed publisher
    Thirty-one limonoids and one tirucallane-type triterpenoid were isolated from the fruits of Melia azedarach (Meliaceae)...
  30. Saleem R, Ahmed S, Shamim S, Faizi S, Siddiqui B. Antibacterial effect of Melia azedarach flowers on rabbits. Phytother Res. 2002;16:762-4 pubmed
    A methanol extract of Melia azedarach flowers showed potent antibacterial action in rabbits suffering from a skin infection produced by Stapyhlococcus aureus. The healing effects were found comparable to neomycin.
  31. Keshri G, Lakshmi V, Singh M. Pregnancy interceptive activity of Melia azedarach Linn. in adult female Sprague-Dawley rats. Contraception. 2003;68:303-6 pubmed
    Ethanolic extract of the root of Melia azedarach Linn...
  32. Petrera E, Coto C. Therapeutic effect of meliacine, an antiviral derived from Melia azedarach L., in mice genital herpetic infection. Phytother Res. 2009;23:1771-7 pubmed publisher
    ..powerful sources of novel drug discovery, a partially purified extract (meliacine) from the leaves of Melia azedarach L., a plant used in traditional medicine in India for the treatment of several diseases, has been studied...
  33. Cropley T, Hasegawa G. Melia azedarach: new potential for an old medicinal plant. J Am Acad Dermatol. 2007;57:366-7 pubmed
  34. Sousa L, Pires H, Soares S, Ferri P, Ribas P, Lima E, et al. Potential synergistic effect of Melia azedarach fruit extract and Beauveria bassiana in the control of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) in cattle infestations. Vet Parasitol. 2011;175:320-4 pubmed publisher
    The use of a concentrate emulsion of Melia azedarach green fruits and a suspension of the fungus Beauveria bassiana was evaluated in the control of Rhipicephalus microplus on artificially infested cattle...
  35. Szewczuk V, Mongelli E, Pomilio A. In vitro anthelmintic activity of Melia azedarach naturalized in Argentina. Phytother Res. 2006;20:993-6 pubmed
    The anthelmintic activity of the drupe extracts of Melia azedarach L...
  36. Sultana S, Akhtar N, Asif H. Antipyretic effects of hydro-methanol extract of Melia azedarach Linn. seeds and Cucumis melo Linn. seeds in experimental rabbits. Pak J Pharm Sci. 2017;30:1257-1261 pubmed
    To investigate the antipyretic activity of hydro-methanol extract of Melia azedarach Linn. (HMEMA) seeds and Cucumis melo Linn. (HMECM) seeds in experimental animals...
  37. Saleem R, Rani R, Ahmed M, Sadaf F, Ahmad S, ul Zafar N, et al. Effect of cream containing Melia azedarach flowers on skin diseases in children. Phytomedicine. 2008;15:231-6 pubmed publisher
    A herbal cream containing a methanolic HPLC-standardized extract of Melia azedarach flowers has been prepared and found potent against bacterial skin diseases like cellulitis, pustules, pyogenic infections, etc. in children...
  38. Defago M, Valladares G, Banchio E, Carpinella C, Palacios S. Insecticide and antifeedant activity of different plant parts of Melia azedarach on Xanthogaleruca luteola. Fitoterapia. 2006;77:500-5 pubmed
    ..bioassays, treatment of elm leaves with extracts obtained from unripe fruits and green or senescent leaves of Melia azedarach at 1-10% concentration significantly deterred feeding by adults of the elm leaf beetle, Xanthogaleruca ..
  39. Petrera E, Coto C. Effect of the potent antiviral 1-cinnamoyl-3,11-dihydroxymeliacarpin on cytokine production by murine macrophages stimulated with HSV-2. Phytother Res. 2014;28:104-9 pubmed publisher
    The limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin (CDM) isolated from leaf extracts of Melia azedarach L, has potent antiherpetic effect in epithelial cells...
  40. Isman M. Botanical insecticides, deterrents, and repellents in modern agriculture and an increasingly regulated world. Annu Rev Entomol. 2006;51:45-66 pubmed
  41. Mroginski L, Rey H. Micropropagation of paradise tree (Melia azedarach) by in vitro culture of axillary buds. Methods Mol Biol. 2013;11013:223-30 pubmed publisher
    Paradise tree (Melia azedarach L.) is a multipurpose ornamental and timber tree, and its extracts are used to make insecticides and fungicides...
  42. Kikuchi T, Pan X, Ishii K, Nakamura Y, Ogihara E, Koike K, et al. Cytotoxic and apoptosis-inducing activities of 12-O-Acetylazedarachin B from the fruits of Melia azedarach in human cancer cell lines. Biol Pharm Bull. 2013;36:135-9 pubmed
    12-O-Acetylazedarachin B (1), isolated from the fruit extract of Melia azedarach, exhibited potent cytotoxicity against leukemia (HL-60) (IC(50) 0.016?µM) and stomach (AZ521) (IC(50) 0.035?µM) cancer cell lines...
  43. de Sousa L, Soares S, Pires H. [Evaluation of efficacy of ripe and unripe fruit oil extracts of Melia azedarach against Rhipicephalus (Boophilus) microplus (Acari: ixodidae)]. Rev Bras Parasitol Vet. 2008;17:36-40 pubmed
    Hexanic extracts gotten of the fruits of cinamomo (Melia azedarach) were tested on engorged females and larvae of Rhipicephalus (Boophilus) microplus...
  44. Zhou F, Ma X, Li Z, Li W, Zheng W, Wang Z, et al. Four New Tirucallane Triterpenoids from the Fruits of Melia azedarach and Their Cytotoxic Activities. Chem Biodivers. 2016;13:1738-1746 pubmed publisher
    ..12), along with 16 known analogues, 1, 3 - 7, 9 - 10, and 13 - 20, were isolated from the fruits of Melia azedarach. Their structures were elucidated by spectroscopic methods including 1D- and 2D-NMR techniques and mass ..
  45. del Mendez M, Elias F, Aragao M, Gimeno E, Riet Correa F. Intoxication of cattle by the fruits of Melia azedarach. Vet Hum Toxicol. 2002;44:145-8 pubmed
    b>Melia azedarach fruits were administered at single doses ranging from 5 to 30 g/kg bw to 10 calves. The animals dosed with 25 g/kg bw and 30 g/ kg bw died, as well as 1/2 cattle that received 15 g/kg bw...
  46. Ferreiro D, Orozco J, Miron C, Real T, Hernández Moreno D, Soler F, et al. Chinaberry tree (Melia azedarach) poisoning in dog: a case report. Top Companion Anim Med. 2010;25:64-7 pubmed publisher
    ..In addition, we compare clinical and gross postmortem findings in other similar cases reported in the literature. There is a general lack of information of such poisoning in pets...
  47. Zhang A, He L, Gao J, Xu X, Li S, Bai M, et al. Metabolites from an endophytic fungus sphaceloma sp. LN-15 isolated from the leaves of Melia azedarach. Lipids. 2009;44:745-51 pubmed publisher
    ..LN-15 isolated from the leaves of Melia azedarach L. and grown in pure culture...
  48. Alché L, Ferek G, Meo M, Coto C, Maier M. An antiviral meliacarpin from leaves of Melia azedarach L. Z Naturforsch C. 2003;58:215-9 pubmed
    Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 microM and 20 microM for vesicular ..
  49. Vila S, Rey H, Mroginski L. Influence of genotype and explant source on indirect organogenesis by in vitro culture of leaves of Melia azedarach L. Biocell. 2004;28:35-41 pubmed
    In vitro regeneration of shoots from leaf explants of the Paradise tree (Melia azedarach L.) was studied...
  50. Marimuthu S, Balakrishnan P, Nair S. Phytochemical investigation and radical scavenging activities of Melia azedarach and its DNA protective effect in cultured lymphocytes. Pharm Biol. 2013;51:1331-40 pubmed publisher
    b>Melia azedarach Linn (Meliaceae) is an Ayurvedic medicinal plant which is native to India...
  51. Kamaraj C, Rahuman A, Bagavan A, Mohamed M, Elango G, Rajakumar G, et al. Ovicidal and larvicidal activity of crude extracts of Melia azedarach against Haemonchus contortus (Strongylida). Parasitol Res. 2010;106:1071-7 pubmed publisher
    ..out to evaluate the anthelmintic activity of the leaves and seed aqueous and hydro-alcoholic extracts of Melia azedarach L...
  52. Yuan C, Zhang Y, Tang G, Li Y, He H, Li S, et al. Cytotoxic limonoids from Melia azedarach. Planta Med. 2013;79:163-8 pubmed publisher
    ..one steroid, and one sesquiterpenoid, along with nine known limonoids (6-14), were isolated from the bark of Melia azedarach. The structures of the new compounds were elucidated by 2D NMR spectroscopy and mass spectrometry...
  53. Fill T, da Silva J, de Oliveira K, da Silva B, Rodrigues Fo E. Oxidative potential of some endophytic fungi using 1-indanone as a substrate. J Microbiol Biotechnol. 2012;22:832-7 pubmed
    ..potential of the fungus Penicillium brasilianum, a strain isolated as an endophyte from a Meliaceae plant (Melia azedarach), was investigated using 1-indanone as a substrate to track the production of monooxygenases...
  54. Scocchi A, Vila S, Mroginski L, Engelmann F. Cryopreservation of somatic embryos of paradise tree (Melia azedarach L.). Cryo Letters. 2007;28:281-90 pubmed
    In paradise tree (Melia azedarach L.), immature zygotic embryos sampled from immature fruits are the starting material for the production of somatic embryos. These somatic embryos are employed for freezing experiments...
  55. Mandal R, Dhaliwal P. Antifertility effect of Melia azedarach Linn. (dharek) seed extract in female albino rats. Indian J Exp Biol. 2007;45:853-60 pubmed
    In the present study, the effect of oral administration of Melia azedarach Linn...
  56. Bueno C, Barquero A, Di Cónsoli H, Maier M, Alché L. A natural tetranortriterpenoid with immunomodulating properties as a potential anti-HSV agent. Virus Res. 2009;141:47-54 pubmed publisher
    Meliacine (MA), an antiviral principle present in partially purified leaf extracts of Melia azedarach L...
  57. Bueno C, Alché L, Barquero A. 1-Cinnamoyl-3,11-dihydroxymeliacarpin delays glycoprotein transport restraining virus multiplication without cytotoxicity. Biochem Biophys Res Commun. 2010;393:32-7 pubmed publisher
    The 1-cinnamoyl-3,11-dihydroxymeliacarpin (CDM), isolated from extracts of Melia azedarach L., displays antiviral and immunomodulating properties...
  58. Abbasi A, Khan M, Ahmad M, Zafar M, Jahan S, Sultana S. Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, Pakistan. J Ethnopharmacol. 2010;128:322-35 pubmed publisher
    ..The present investigation is an attempt to find out ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics...
  59. Keshri G, Bajpai M, Lakshmi V, Setty B, Gupta G. Role of energy metabolism in the pregnancy interceptive action of Ferula assafoetida and Melia azedarach extracts in rat. Contraception. 2004;70:429-32 pubmed
    Ethanolic extract of Ferula assafoetida and chloroform fraction of Melia azedarach, both devoid of estrogenic activity, were examined for their pregnancy interceptive property...
  60. Charleston D, Gols R, Hordijk K, Kfir R, Vet L, Dicke M. Impact of botanical pesticides derived from Melia azedarach and Azadirachta indica plants on the emission of volatiles that attract Parasitoids of the diamondback moth to cabbage plants. J Chem Ecol. 2006;32:325-49 pubmed
    ..Aqueous leaf extracts from the syringa tree Melia azedarach and commercial formulations from the neem tree Azadirachta indica, Neemix 4...
  61. González Zamora J, Lopez C, Avilla C. Population studies of arthropods on Melia azedarach in Seville (Spain), with special reference to Eutetranychus orientalis (Acari: Tetranychidae) and its natural enemies. Exp Appl Acarol. 2011;55:389-400 pubmed publisher
    Eutetranychus orientalis has become an important pest of the ornamental tree Melia azedarach in the city of Seville (Spain). Trees suffer total defoliation at the end of summer...
  62. Song C, Lin C, Tian G, Zhao W, Zhu S, Mou H, et al. [Complete sequence of a full-length DNA and molecular characterization of one plasmid from chinaberry (Melia azedarach Z) witches'-broom phytoplasma]. Wei Sheng Wu Xue Bao. 2011;51:1158-67 pubmed
    ..To clone plasmid from chinaberry witches'-broom phytoplasma and analyse its molecular characterization...
  63. Geris dos Santos R, Rodrigues Fo E. Meroterpenes from Penicillium sp found in association with Melia azedarach. Phytochemistry. 2002;61:907-12 pubmed
    A Penicillium sp was isolated from the root bark of Melia azedarach and cultivated over sterilized rice...
  64. Yang S, Wang H, Gao J, Zhang Q, Laatsch H, Kuang Y. Fusaroside, a unique glycolipid from Fusarium sp., an endophytic fungus isolated from Melia azedarach. Org Biomol Chem. 2012;10:819-24 pubmed publisher
    ..LN-11 isolated from the leaves of Melia azedarach. Six known compounds, phalluside (2), (9R*,10R*,7E)-6, 9,10-trihydroxyoctadec-7-enoic acid (3), porrigenic ..
  65. Yang S, Gao J, Laatsch H, Tian J, Pescitelli G. Absolute configuration of fusarone, a new azaphilone from the endophytic fungus Fusarium sp. isolated from Melia azedarach, and of related azaphilones. Chirality. 2012;24:621-7 pubmed publisher
    ..LN-12, isolated from the leaves of Melia azedarach Linn...
  66. Kumazawa S, Kubota S, Yamamoto H, Okamura N, Sugiyamab Y, Kobayashia H, et al. Antiangiogenic activity of flavonoids from Melia azedarach. Nat Prod Commun. 2013;8:1719-20 pubmed
    ..3-O-robinobioside) and 3 (kaempferol 3-O-rutinoside) were isolated from the subcritical water extracts of Melia azedarach leaves...
  67. dos Santos R, Rodrigues Fo E. Further meroterpenes produced by Penicillium sp., an endophyte obtained from Melia azedarach. Z Naturforsch C. 2003;58:663-9 pubmed
    ..The fungus was isolated from the root bark of Melia azedarach after surface sterilization...
  68. Kebede Y, Gebre Michael T, Balkew M. Laboratory and field evaluation of neem (Azadirachta indica A. Juss) and Chinaberry (Melia azedarach L.) oils as repellents against Phlebotomus orientalis and P. bergeroti (Diptera: Psychodidae) in Ethiopia. Acta Trop. 2010;113:145-50 pubmed publisher
    The study evaluated the efficacy of neem (Azadirachta indica A. Juss.) and Chinaberry (Melia azedarach L.) seed oils as repellents against laboratory and field populations of some sandflies in Ethiopia...
  69. Yang Y, Xiao Y, Liu B, Fang X, Yang W, Xu J. Comparison of headspace solid-phase microextraction with conventional extraction for the analysis of the volatile components in Melia azedarach. Talanta. 2011;86:356-61 pubmed publisher
    The volatile compositions of Melia azedarach were studied by headspace solid-phase microextraction (HS-SPME). The result was compared with that obtained by soxhlet extraction (SE) and ultrasonic extraction (UAE)...
  70. He L, Yin N, Cheng J, Wu X, Jiang J, Song X. Structural features of a new heteropolysaccharide from the fruit bodies of Melia azedarach and its effect on cytotoxic activity. Fitoterapia. 2009;80:399-403 pubmed publisher
    Water-soluble polysaccharides were extracted from the fruit pulps of Melia azedarach and some columns were undertaken to isolate the major polysaccharide (MPS-III)...
  71. Trudel R, Bomblies A. Larvicidal effects of Chinaberry (Melia azederach) powder on Anopheles arabiensis in Ethiopia. Parasit Vectors. 2011;4:72 pubmed publisher
    ..The containers were monitored daily and larvae, pupae and adult mosquitoes were counted. This experimental procedure was replicated three times...
  72. Brunherotto R, Vendramim J, de G Oriani M. [Effects of tomato genotypes and aqueous extracts of Melia azedarach leaves and Azadirachta indica seeds on Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae)]. Neotrop Entomol. 2010;39:784-91 pubmed
    ..We investigated the effects of aqueous extracts of Melia azedarach leaves and Azadirachta indica seeds and three tomato genotypes, 'Santa Clara', 'IPA-5'--Solanum lycopersicum (..
  73. Lee J, Ko N, Kim N, Mun S, Kim J, Her E, et al. Meliae cortex extract exhibits anti-allergic activity through the inhibition of Syk kinase in mast cells. Toxicol Appl Pharmacol. 2007;220:227-34 pubmed
    ..Taken together, these results suggest that the anti-allergic activity of MC may be due to the inhibition of histamine secretion and cytokine expression through the Syk inhibition in mast cells...
  74. Petrera E, Coto C. The synergistic effect of IFN-alpha and IFN-gamma against HSV-2 replication in Vero cells is not interfered by the plant antiviral 1-cinnamoyl-3, 11-dihydroxymeliacarpin. Virol J. 2006;3:45 pubmed
    ..For this purpose we studied the effect of the compound 1-cinnamoyl-3,11-dihydroxymeliacarpin (CDM), which is the responsible for meliacine antiviral action, on the HSV-2 inhibition exerted by IFN alpha, IFN-gamma or their combination...
  75. Fill T, Geris dos Santos R, Barisson A, Rodrigues Filho E, Souza A. Co-production of bisphenylpropanoid amides and meroterpenes by an endophytic Penicillium brasilianum found in the root bark of Melia azedarach. Z Naturforsch C. 2009;64:355-60 pubmed
    A fungus, isolated from the root bark of Melia azedarach (Meliaceae), from which a series of meroterpenes have been reported, was identified as Penicillium brasilianum based on analysis of the ITS region of ribosomal DNA...
  76. Zhou H, Hamazaki A, Fontana J, Takahashi H, Esumi T, Wandscheer C, et al. New ring C-seco limonoids from Brazilian Melia azedarach and their cytotoxic activity. J Nat Prod. 2004;67:1544-7 pubmed
    A methanol extract of the ripe fruits of Melia azedarach collected in Curitiba, Parana, Brazil, afforded seven new ring C-seco limonoids (1-7) together with three known limonoids (8-10)...
  77. Rajeswary H, Vasuki R, Samudram P, Geetha A. Hepatoprotective action of ethanolic extracts of Melia azedarach Linn. and Piper longum Linn and their combination on CCl4 induced hepatotoxicity in rats. Indian J Exp Biol. 2011;49:276-81 pubmed
    ..Among these extracts, BHE showed similar hepatoprotective action to silymarin, which was the positive control in this study...
  78. Aoudia H, Ntalli N, Aissani N, Yahiaoui Zaidi R, Caboni P. Nematotoxic phenolic compounds from Melia azedarach against Meloidogyne incognita. J Agric Food Chem. 2012;60:11675-80 pubmed publisher
    In the present study, evaluated was the paralysis activity of whole Italian and Algerian Melia azedarach, commonly known as chinaberry, fruits and parts (seeds, wood, and kernels) against Meloidogyne incognita second stage juveniles (J(2)..
  79. Cala A, Chagas A, Oliveira M, Matos A, Borges L, Sousa L, et al. In vitro anthelmintic effect of Melia azedarach L. and Trichilia claussenii C. against sheep gastrointestinal nematodes. Exp Parasitol. 2012;130:98-102 pubmed publisher
    ..Thus, the aim of this study was to evaluate the in vitro anthelmintic effect of plant extracts from Melia azedarach and Trichilia claussenii by the egg hatch test (EHT) and larval development test (LDT) against sheep ..