Summary: A plant genus of the family SCROPHULARIACEAE. Members contain mimengoside B, verbascoside, and phenylethanoids.

Top Publications

  1. Cortés A, Delgadillo A, Hurtado M, Domínguez Ramírez A, Medina J, Aoki K. The antispasmodic activity of Buddleja scordioides and Buddleja perfoliata on isolated intestinal preparations. Biol Pharm Bull. 2006;29:1186-90 pubmed
    The antispasmodic activity of extracts from the aerial parts of Buddleja scordioides and Buddleja perfoliata (family: Scrophulariaceae) was studied on isolated tissue preparations from rabbit and guinea pig intestine...
  2. Sultana N, Akhter M, Khan R, Afza N, Tareen R, Malik A. Nematicidal natural products from the aerial parts of Buddleja crispa. Nat Prod Res. 2010;24:783-8 pubmed publisher
    Studies on the aerial parts of Buddleja crispa yielded 13 known compounds, nonyl benzoate, hexyl p-hydroxy-cinnamate, ginipin, gardiol, 1-heptacosanol, steroidal galactoside (22 R)-stigmasta-7,9 (11)-dien-22 beta-ol-3beta-O-beta-D-..
  3. Hallac B, Sannigrahi P, Pu Y, Ray M, Murphy R, Ragauskas A. Biomass characterization of Buddleja davidii: a potential feedstock for biofuel production. J Agric Food Chem. 2009;57:1275-81 pubmed publisher
    A compositional analysis was performed on Buddleja davidii to determine its general biomass characteristics and provide detailed analysis of the chemical structures of its cellulose and lignin using NMR. B...
  4. Oh W, Jung U, Eom H, Shin H, Park H. Inhibition of lipopolysaccharide-induced proinflammatory responses by Buddleja officinalis extract in BV-2 microglial cells via negative regulation of NF-kB and ERK1/2 signaling. Molecules. 2013;18:9195-206 pubmed publisher
    b>Buddleja officinalis has been traditionally used in the supportive treatment of inflammatory and neuronal diseases in Korea and China...
  5. Lee Y, Kim J, Kang D, Lee H. Buddleja officinalis suppresses high glucose-induced vascular smooth muscle cell proliferation: role of mitogen-activated protein kinases, nuclear factor-kappaB and matrix metalloproteinases. Exp Biol Med (Maywood). 2010;235:247-55 pubmed publisher
    ..Thus, we aimed to investigate whether an ethanol extract of Buddleja officinalis (EBO) suppresses high glucose-induced proliferation in primary cultured human aortic smooth muscle ..
  6. Kim Y, Lee Y, Choi E. Linarin isolated from Buddleja officinalis prevents hydrogen peroxide-induced dysfunction in osteoblastic MC3T3-E1 cells. Cell Immunol. 2011;268:112-6 pubmed publisher
    The flowers and leaves buds of Buddleja officinalis MAXIM (Buddlejaceae) are used to treat eye troubles, hernia, gonorrhea and liver troubles in Asia. To elucidate the protective effects of linarin isolated from B...
  7. Houghton P, Mensah A, Iessa N, Hong L. Terpenoids in Buddleja: relevance to chemosystematics, chemical ecology and biological activity. Phytochemistry. 2003;64:385-93 pubmed
    The terpenoids reported from Buddleja species are described. The antifungal activity of chloroform extracts of B. cordata and B...
  8. Adedapo A, Jimoh F, Koduru S, Masika P, Afolayan A. Assessment of the medicinal potentials of the methanol extracts of the leaves and stems of Buddleja saligna. BMC Complement Altern Med. 2009;9:21 pubmed publisher
    b>Buddleja saligna Willd (Loganiaceae) is a small to medium-sized evergreen tree; trunk short, often gnarled and crooked; crown dense, rounded or domed-shaped; foliage greyish green...
  9. Avila Acevedo J, Castañeda C, Benitez F, Durán D, Barroso V, Martinez C, et al. Photoprotective activity of Buddleja scordioides. Fitoterapia. 2005;76:301-9 pubmed
    The purpose of this study was to determine the photoprotective properties of the methanolic extract of Buddleja scordioides, as well as verbascoside and linarin which were isolated from this extract, and linarin acetate prepared in the ..

More Information


  1. Lee Y, Kang D, Kim J, Lee H. Effect of Buddleja officinalis on high-glucose-induced vascular inflammation in human umbilical vein endothelial cells. Exp Biol Med (Maywood). 2008;233:694-700 pubmed publisher
    In this study, we aimed to investigate whether an aqueous extract of Buddleja officinalis (ABO) suppresses high-glucose-induced vascular inflammatory processes in the primary cultured human umbilical vein endothelial cells (HUVEC)...
  2. Backhouse N, Rosales L, Apablaza C, Goïty L, Erazo S, Negrete R, et al. Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae. J Ethnopharmacol. 2008;116:263-9 pubmed publisher
    b>Buddleja globosa, known as "matico", is employed in Chile for wound healing.
  3. Feng Y, Auge H, Ebeling S. Invasive Buddleja davidii allocates more nitrogen to its photosynthetic machinery than five native woody species. Oecologia. 2007;153:501-10 pubmed
    ..In this study, ecophysiological traits of eight populations of the invasive shrub Buddleja davidii from a wide range of European locations and five co-occurring native woody species in Germany were ..
  4. Lee D, Ha N, Bu Y, Choi H, Park Y, Kim Y, et al. Neuroprotective effect of Buddleja officinalis extract on transient middle cerebral artery occlusion in rats. Biol Pharm Bull. 2006;29:1608-12 pubmed
    The flower buds of Buddleja officinalis MAXIM (Loganiaceae) are used to treat headache and inflammatory diseases in traditional Korean medicine. In the present study, the neuroprotective effects of the methanolic extract of B...
  5. Lee Y, Moon M, Hwang S, Yoon J, Lee S, Seo K, et al. Anti-Inflammatory effect of Buddleja officinalis on vascular inflammation in human umbilical vein endothelial cells. Am J Chin Med. 2010;38:585-98 pubmed
    ..In this study, we investigated whether and by what mechanisms an aqueous extract of Buddleja officinalis (ABO) inhibited the expressions of cellular adhesion molecules, which are relevant to inflammation ..
  6. Petrakis E, Polissiou M. Assessing saffron (Crocus sativus L.) adulteration with plant-derived adulterants by diffuse reflectance infrared Fourier transform spectroscopy coupled with chemometrics. Talanta. 2017;162:558-566 pubmed publisher
    ..e. C. sativus stamens, calendula, safflower, turmeric, buddleja, and gardenia...
  7. Pellegrini M, Alonso Salces R, Umpierrez M, Rossini C, Fuselli S. Chemical Composition, Antimicrobial Activity, and Mode of Action of Essential Oils against Paenibacillus larvae, Etiological Agent of American Foulbrood on Apis mellifera. Chem Biodivers. 2017;14: pubmed publisher
    ..Acantholippia seriphioides, Schinus molle, Solidago chilensis, Lippia turbinata, Minthostachys mollis, Buddleja globosa, and Baccharis latifolia essential oils (EOs), and to evaluate their antibacterial activities and their ..
  8. Sun M, Luo Z, Liu Y, Yang R, Lu L, Yu G, et al. Identification of the Major Components of Buddleja officinalis Extract and Their Metabolites in Rat Urine by UHPLC-LTQ-Orbitrap. J Food Sci. 2016;81:H2587-H2596 pubmed publisher
    b>Buddleja officinalis Maxim, one of the most popular herbal medicines in China, is widely prescribed for curing eye diseases for centuries. In this study, the major components of B...
  9. Suwalsky M, Duguet J, Speisky H. An In Vitro Study of the Antioxidant and Antihemolytic Properties of Buddleja globosa (Matico). J Membr Biol. 2017;250:239-248 pubmed publisher
    The antioxidant and antihemolytic properties contained in the leaves of Buddleja globosa (B. globosa), also known as "Matico," were determined...
  10. Xie G, Li R, Han Y, Zhu Y, Wu G, Qin M. Optimization of the Extraction Conditions for Buddleja officinalis Maxim. Using Response Surface Methodology and Exploration of the Optimum Harvest Time. Molecules. 2017;22: pubmed publisher
    ..liquid to solid ratio (20:1 to 40:1 mL/g) and extraction time (20-40 min) on the yield of 11 constituents from Buddleja officinalis Maxim using ultrasound-assisted extraction...
  11. Zhang H, Tao L. [Studies on the chemical constituents of Buddleja albiflora (II)]. Zhong Yao Cai. 2010;33:922-4 pubmed
    To study the chemical constituents of Buddleja albiflora. The constituents were isolated by column chromatography and their structures were elucidated by spectroscopic analyses...
  12. Gutierrez R, Solis R, Baez E, Martinez F. Effect on capillary permeability in rabbits of iridoids from Buddleia scordioides. Phytother Res. 2006;20:542-5 pubmed
    ..A comparison was made between the action of the iridoids and a known inhibitor of vascular permeability, troxerutin (50 mg/kg). Methylcatalpol and catalpol were found to be less effective than troxerutin. ..
  13. Li Y, Lu J, Li Q, Zhao Y, Pu X. Pedicularioside A from Buddleia lindleyana inhibits cell death induced by 1-methyl-4-phenylpyridinium ions (MPP+) in primary cultures of rat mesencephalic neurons. Eur J Pharmacol. 2008;579:134-40 pubmed
    ..The mode of action appears to be the inhibition of caspase-3 gene expression, thereby protecting mesencephalic neurons from MPP(+)-induced cell death. ..
  14. Letelier M, Molina Berríos A, Cortés Troncoso J, Jara Sandoval J, Holst M, Palma K, et al. DPPH and oxygen free radicals as pro-oxidant of biomolecules. Toxicol In Vitro. 2008;22:279-86 pubmed
    ..Cu2+/ascorbate was used as generator system of oxygen free radical and as antioxidant, an extract of Buddleja globosa's leaves...
  15. Ahrazem O, Diretto G, Argandoña J, Rubio Moraga A, Julve J, Orzaez D, et al. Evolutionarily distinct carotenoid cleavage dioxygenases are responsible for crocetin production in Buddleja davidii. J Exp Bot. 2017;68:4663-4677 pubmed publisher
    ..Notably, Buddleja davidii accumulates crocetin in its flowers...
  16. Peng Q, Yao X, Wu Q. [Effects of extract of Buddleja officinalis eye drops on androgen receptors of lacrimal gland cells of castrated rats with dry eye]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012;32:72-5, 114 pubmed
    To observe the effects of the extract of Buddleja officinalis eye drops (EBOED) on basic tears secretory volume, tear film stability, and expressions of androgen receptors (AR) in castrated rats with dry eye, and to investigate the ..
  17. Guo H, Koike K, Li W, Satou T, Guo D, Nikaido T. Saponins from the flower buds of Buddleja officinalis. J Nat Prod. 2004;67:10-3 pubmed
    Five new saponins, mimengosides C-G (1-5), were isolated from the flower buds of Buddleja officinalis along with five known compounds, namely, songaroside A, acteoside, phenylethyl 2-glucoside, echinacoside, and phenylethyl alcohol 8-O-..
  18. Tai B, Nhiem N, Quang T, Ngan N, Tung N, Kim Y, et al. A new iridoid and effect on the rat aortic vascular smooth muscle cell proliferation of isolated compounds from Buddleja officinalis. Bioorg Med Chem Lett. 2011;21:3462-6 pubmed publisher
    ..5), flavonoids (6-8), triterpenoids (9-14), and phenylethanoids (15-20) were isolated from the flowers of Buddleja officinalis...
  19. Davis T, Kline D, Kaufman P. Aedes albopictus (Diptera: Culicidae) Oviposition Preference as Influenced by Container Size and Buddleja davidii Plants. J Med Entomol. 2016;53:273-8 pubmed
    ..for containers of three selected sizes (473, 946 and 1,892 ml) and the influence of flowering butterfly bush (Buddleja davidii Franchett cultivar 'Guinevere') plants were examined...
  20. Ahmad I, Chen S, Peng Y, Chen S, Xu L. Lipoxygenase inhibiting and antioxidant iridoids from Buddleja crispa. J Enzyme Inhib Med Chem. 2008;23:140-3 pubmed
    Phytochemical investigations on the ethyl acetate-soluble fraction of the whole plant of Buddleja crispa led to the isolation of the iridoids 1-7...
  21. Peng Q, Yao X, Wu Q, Tan H, Zhang J. Effects of eye drops of Buddleja officinalis Maxim. extract on lacrimal gland cell apoptosis in castrated rats with dry eye. Zhong Xi Yi Jie He Xue Bao. 2010;8:244-9 pubmed
    To explore the possible mechanism of eye drops of Buddleja officinalis extract in treating dry eye of castrated rats by analyzing the expressions of Bax and Bcl-2 proteins...
  22. Lee Y, Kang D, Kim J, Lee H. Buddleja officinalis inhibits high glucose-induced matrix metalloproteinase activity in human umbilical vein endothelial cells. Phytother Res. 2008;22:1655-9 pubmed publisher
    The aim of the present investigation was to investigate whether an aqueous extract of Buddleja officinalis (ABO), a traditional Korean herbal medicine, suppresses the endothelial extracellular matrix degradation under high glucose ..
  23. Schreiter S, Ebeling S, Durka W. Polymorphic microsatellite markers in the invasive shrub Buddleja davidii (Scrophulariaceae). Am J Bot. 2011;98:e39-40 pubmed publisher
    Microsatellite primers were developed for the invasive plant Buddleja davidii, a Chinese shrub that is an invader in most other continents.
  24. Peng Q, Yao X, Wu Q, Chen M. [Effects of extract of Buddleja officinalis on prevention of dry eye in castrated rabbits]. Zhonghua Yan Ke Za Zhi. 2008;44:1011-9 pubmed
    To assess the preventive effects of extract of Buddleja officinalis on dry eye in castrated rabbits and to discuss the mechanism of these effects.
  25. Wu D, Wang Y, Wang X, Liu J, Jin C, Zhang W. [Study on the chemical composition of triterpenoid from the fruit of Buddleja lindleyana and their neuroprotective activitiy]. Zhong Yao Cai. 2011;34:1884-7 pubmed
    To study the chemical composition of triterpenoid from the fruit of Buddleja lindleyana.
  26. Mahlke J, Boligon A, Machado M, Athayde M. Composition of the essential oil of Buddleja thyrsoides Lam. leaves from Brazil. Nat Prod Res. 2013;27:1319-22 pubmed publisher
    This study is designed to examine the chemical composition of the essential oil obtained from Buddleja thyrsoides Lam leaves from south Brazil...
  27. Filho A, Morel A, Adolpho L, Ilha V, Giralt E, Tarrago T, et al. Inhibitory effect of verbascoside isolated from Buddleja brasiliensis Jacq. ex Spreng on prolyl oligopeptidase activity. Phytother Res. 2012;26:1472-5 pubmed publisher
    ..1) has been isolated as the main constituent of the crude extract of Buddleja brasiliensis Jacq. ex Spreng from Southern Brazil...
  28. Barkatullah -, Ibrar M, Ikram N, Rauf A, Hadda T, Bawazeer S, et al. In vivo antinociceptive and muscle relaxant activity of leaf and bark of Buddleja asiatica L. Pak J Pharm Sci. 2016;29:1509-1512 pubmed
    ..study was designed to assess the antinociceptive and skeleton muscle relaxant effect of leaves and barks of Buddleja asiatica in animal models...
  29. Houghton P, Hylands P, Mensah A, Hensel A, Deters A. In vitro tests and ethnopharmacological investigations: wound healing as an example. J Ethnopharmacol. 2005;100:100-7 pubmed
    ..Approaches to the in vitro investigations of wound healing processes are exemplified by studies on extracts of Buddleja species and three Ghanaian species Spathodea campanulata, Commelina diffusa and Secamone afzelii...
  30. Han B, Chen J, Hao L, Zhou X, Han F, Li L. [Molluscicidal effect of endophyte LL3026 from Buddleia lindleyana against Oncomelania hupensis]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2010;28:210-3 pubmed
    ..To research the molluscicidal effect, active components, thermal stability and light stability of endophyte LL3026 (Colletotrichum sp.) from Buddleia lindleyana..
  31. Ahmad I, Anis I, Fatima I, Malik A, Khan S, Afza N, et al. Two new protease-inhibiting glycosphingolipids from Buddleja crispa. Chem Biodivers. 2007;4:917-24 pubmed
    Crispins A (1) and B (2), two new glycosphingolipids, were isolated from the whole plant Buddleja crispa, along with three known compounds: alpha-amyrin, linoleic acid, and stigmasterol...
  32. Gilani A, Bukhari I, Khan R, Shah A, Ahmad I, Malik A. Presence of blood-pressure lowering and spasmolytic constituents in Buddleja crispa. Phytother Res. 2009;23:492-7 pubmed publisher
    This aim of this study was to investigate the crude extract of Buddleja crispa (Bc.Cr) and its active constituent(s) for their antihypertensive and antispasmodic activities. The Bc...
  33. Andersson S, Dobson H. Antennal responses to floral scents in the butterfly Heliconius melpomene. J Chem Ecol. 2003;29:2319-30 pubmed
    ..Verbenaceae) and Warszewiczia coccinea (Vahl) Kl. (Rubiaceae), and two temperate species, Buddleja davidii Franchet (Loganiaceae) and Cirsium arvense (L.) Scop. (Asteraceae)...
  34. Hallac B, Ray M, Murphy R, Ragauskas A. Correlation between anatomical characteristics of ethanol organosolv pretreated Buddleja davidii and its enzymatic conversion to glucose. Biotechnol Bioeng. 2010;107:795-801 pubmed publisher
    b>Buddleja davidii is a unique biomass that has many attractive agroenergy features, especially its wide range of growth habitat. The anatomical characteristics of B...
  35. Tai B, Jung B, Cuong N, Linh P, Tung N, Nhiem N, et al. Total peroxynitrite scavenging capacity of phenylethanoid and flavonoid glycosides from the flowers of Buddleja officinalis. Biol Pharm Bull. 2009;32:1952-6 pubmed
    ..6) and three flavonoids; linarin (7); apigenin (8); isorhoifolin (9), were isolated from the flowers of Buddleja officinalis MAXIM. (Buddlejaceae)...
  36. Zhang Y, Li C, Zhang C, Tao B. [Study on the chemical constituents of Buddleja purdomii]. Zhong Yao Cai. 2005;28:994-5 pubmed
    To study the chemical constituents of Buddleja purdomii W. W Smith.
  37. Zhang W, Tang S, Duan H. [Studies on chemical constituents of rhizome of Buddleia davidii]. Zhong Yao Cai. 2009;32:515-7 pubmed
    ..To study the chemical constituents of Rhizome of Buddleia davidii...
  38. Peng X, Li C. [Study on the flavanone constitutes of Buddleja davidii]. Zhong Yao Cai. 2011;34:1534-7 pubmed
    To study the chemical constitutes of Buddleja davidii.
  39. Ali F, Khan H, Afzal M, Samad A, Khan S, Ali I. Two new cholinesterase inhibitors asiatoates A and B from Buddleja asiatica. J Asian Nat Prod Res. 2013;15:631-7 pubmed publisher
    ..new benzoates, asiatoate A (1) and asiatoate B (2), have been isolated from the ethyl acetate soluble fraction of Buddleja asiatica whole plant. Their structures were elucidated with the help of spectroscopic data...
  40. Dickie I, Thomas M, Bellingham P. On the perils of mycorrhizal status lists: the case of Buddleja davidii. Mycorrhiza. 2007;17:687-688 pubmed publisher
    One observation in a mycorrhizal check-list that Buddleja davidii is nonmycorrhizal has been perpetuated in subsequent citations and used in a number of analyses of mycorrhizal ecology and evolution. Direct observation of B...
  41. Chukwujekwu J, Rengasamy K, de Kock C, Smith P, Slavětínská L, van Staden J. Alpha-glucosidase inhibitory and antiplasmodial properties of terpenoids from the leaves of Buddleja saligna Willd. J Enzyme Inhib Med Chem. 2016;31:63-6 pubmed publisher
    In our continuing search for biologically active natural product(s) of plant origin, Buddleja saligna, a South African medicinal plant, was screened in line with its traditional use for antidiabetic (yeast alpha glucosidase inhibitory) ..
  42. Han B, Guo D, Chen J, Mao J. Effects of AIBL on Oncomelania hupensis, the intermediate snail host of Schistosoma japonicum: an enzyme histochemical study. Asian Pac J Trop Med. 2012;5:966-9 pubmed publisher
    ..To explore the effect of AIBL on Oncomelania hupensis, the intermediate snail host of Schistosoma japonicum...
  43. Ahmad I, Ahmad N, Wang F. Antioxidant phenylpropanoid glycosides from Buddleja davidii. J Enzyme Inhib Med Chem. 2009;24:993-7 pubmed publisher
    Phytochemical investigations on the n-BuOH-soluble fraction of the whole plant of Buddleja davidii led to the isolation of the phenylpropanoid glycosides 1-10. Their structures were determined by 1D and 2D NMR spectroscopic techniques...
  44. Vertuani S, Beghelli E, Scalambra E, Malisardi G, Copetti S, Dal Toso R, et al. Activity and stability studies of verbascoside, a novel antioxidant, in dermo-cosmetic and pharmaceutical topical formulations. Molecules. 2011;16:7068-80 pubmed publisher
    ..Verbascoside was also stable in suppositories, an interesting pharmaceutical form for possible applications in treatment of inflammation of the intestinal mucosa...
  45. Fialho M, Brusco I, da Silva Brum E, Piana M, Boligon A, Trevisan G, et al. Buddleja thyrsoides Lam. crude extract presents antinociceptive effect on an arthritic pain model in mice. Biochem J. 2017;474:2993-3010 pubmed publisher
    ..Therapeutic tools used for treating inflammatory pain are associated with several undesirable effects. Buddleja thyrsoides Lam...
  46. Juárez Z, Sánchez Arreola E, Bach H, Hernández L. Protective antifungal activity of essential oils extracted from Buddleja perfoliata and Pelargonium graveolens against fungi isolated from stored grains. J Appl Microbiol. 2016;120:1264-70 pubmed publisher
    The chemical composition and antifungal activity of essential oils extracted from Buddleja perfoliata and Pelargonium graveolens were analysed to assess their efficacy as a potential alternative to synthetic chemical fungicides to protect ..
  47. Sheng G, Zhang J, Pu X, Ma J, Li C. Protective effect of verbascoside on 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in PC12 cells. Eur J Pharmacol. 2002;451:119-24 pubmed
    ..effects of verbascoside, one of phenylpropanoid glucoside isolated from the Chinese herbal medicine Buddleja officinalis Maxim, on 1-methyl-4-phenylpyridinium ion (MPP(+)) induced apoptosis and oxidative stress in PC12 ..
  48. Backhouse N, Delporte C, Apablaza C, Farías M, Goïty L, Arrau S, et al. Antinociceptive activity of Buddleja globosa (matico) in several models of pain. J Ethnopharmacol. 2008;119:160-5 pubmed publisher
    Leaf extracts of Buddleja globosa (Buddlejaceae) are used in Chilean folk medicine for wound healing...
  49. Tao L, Huang J, Zhao Y, Li C. [Chemical constituents in Buddleja albiflora]. Zhongguo Zhong Yao Za Zhi. 2009;34:3043-6 pubmed
    To study the chemical constituents of Buddleja albiflora.
  50. Pendota S, Aderogba M, Ndhlala A, van Staden J. Antimicrobial and acetylcholinesterase inhibitory activities of Buddleja salviifolia (L.) Lam. leaf extracts and isolated compounds. J Ethnopharmacol. 2013;148:515-20 pubmed publisher
    b>Buddleja salviifolia leaves are used for the treatment of eye infections and neurodegenerative conditions by various tribes in South Africa.
  51. Han P, Cui Y, Guo H, Guo D. [Studies on fingerprinting of Flos Buddleja by RP-HPLC]. Zhongguo Zhong Yao Za Zhi. 2004;29:938-40, 966 pubmed
    To establish fingerprinting of Flos Buddleja by using RP-HPLC for the quality control.
  52. Lee J, Woo E, Kang K. Inhibition of lipopolysaccharide-inducible nitric oxide synthase expression by acteoside through blocking of AP-1 activation. J Ethnopharmacol. 2005;97:561-6 pubmed
    ..The inhibitory effect of AP-1 activation by acteoside may be associated with the anti-inflammatory effects of Buddlejae Flos...
  53. El Domiaty M, Wink M, Abdel Aal M, Abou Hashem M, Abd Alla R. Antihepatotoxic activity and chemical constituents of Buddleja asiatica Lour. Z Naturforsch C. 2009;64:11-9 pubmed
    ..catalpol, was isolated from the defatted alcoholic extract of the flowering parts of Buddleja asiatica Lour. (family Scrophulariaceae)...
  54. el Sayed M, Abdel Hameed E, Ahmed W, El Wakil E. Non-phenolic antioxidant compounds from Buddleja asiatica. Z Naturforsch C. 2008;63:483-91 pubmed
    The methanol extract of the leaves of Buddleja asiatica Lour...
  55. Roh C, Park M, Shin H, Jung U, Kim J. Buddleja officinalis Maximowicz extract inhibits lipid accumulation on adipocyte differentiation in 3T3-L1 cells and high-fat mice. Molecules. 2012;17:8687-95 pubmed publisher
    ..In this study, we elucidated that Buddleja officinalis Maximowicz extract significantly inhibited lipid accumulation during 3T3-L1 adipocyte differentiation...
  56. Jensen S, Calis I, Gotfredsen C, Søtofte I. Structural revision of some recently published iridoid glucosides. J Nat Prod. 2007;70:29-32 pubmed
    ..Finally, two alleged iridoid galactosides from Buddleja crispa named buddlejosides A and B (12a and 12b) have been shown to be the corresponding glucosides; the former ..
  57. Gao Y, Cai L, Li H, Li C. [Study on the terpenoids of chemical constituents of Buddleja purdomii (II)]. Zhong Yao Cai. 2007;30:667-9 pubmed
    To study the chemical constituents of Buddleja purdomii W. W. Smith.
  58. Lu J, Zhao Y, Qiao L, Fang Y, Huang Q. [Studies on chemical constituents from Buddleja lindleyana Fert]. Zhongguo Zhong Yao Za Zhi. 2001;26:41-3 pubmed
    To study the chemical constituents of Buddleja lindleyana.
  59. Piao M, Kim M, Lee D, Park Y, Hahm K, Moon Y, et al. Antioxidative constituents from Buddleia officinalis. Arch Pharm Res. 2003;26:453-7 pubmed
    ..In addition, compounds 1-6 revealed weak antifungal activity, and no hemolytic activity...
  60. Wang J, Li O, Liu Y, Xie Q, Huang Z, Tu P, et al. [Preliminary attempt at the speciation of 25-elements in the Chinese medicinal herbs]. Zhongguo Zhong Yao Za Zhi. 2004;29:753-9 pubmed
    ..To make an attempt at the multi-element speciation in the Chinese medicinal herbs by determining the concentrations of 25 elements in different extraction solutions...
  61. Chen H, Xu C, Liu D, An S, Tan R. Buddlin, a new compound from Buddleja asiatica. Fitoterapia. 2005;76:588-9 pubmed
    A new compound, named buddlin (1), was isolated from the whole plant of Buddleja asiatica. Its structure was elucidated from spectral evidence.
  62. Zhang W, Yao Z, Zhang Y, Zhang X, Takaishi Y, Duan H. Immunosuppressive sesquiterpenes from Buddleja daviddi. Planta Med. 2010;76:1882-7 pubmed publisher
    ..2?-acetoxy-4-caryophyllen-8?-ol-3-one (6), and nineteen known compounds were isolated from the ethanol extract of Buddleja daviddi. The structures were elucidated by spectroscopic methods...
  63. Cai Z, Yongpruksa N, Harmata M. Total synthesis of the terpenoid buddledone A: 11-membered ring-closing metathesis. Org Lett. 2012;14:1661-3 pubmed publisher
    ..The first total synthesis of buddledone A was accomplished in seven steps from methyl ethyl ketone (MEK). The key step in the sequence featured an 11-membered ring formation by ring-closing metathesis...
  64. Liu X, Gong C, Fan Y, Eiblmeier M, Zhao Z, Han G, et al. Response pattern of amino compounds in phloem and xylem of trees to soil drought depends on drought intensity and root symbiosis. Plant Biol (Stuttg). 2013;15 Suppl 1:101-8 pubmed publisher
    ..seedlings of Robinia pseudoacacia (nodules with Rhizobium), Hippophae rhamnoides (symbiosis with Frankia) and Buddleja alternifolia (no such root symbiosis) were exposed to control, medium drought and severe drought, corresponding ..
  65. Mahlke J, Boligon A, Machado M, Athayde M. In vitro toxicity, antiplatelet and acetylcholinesterase inhibition of Buddleja thyrsoides Lam. leaves. Nat Prod Res. 2012;26:2223-6 pubmed publisher
    ..A decrease in cholinergic activity is a key event in the biochemical of AD. Buddleja thyrsoides is a plant widely distributed in Southern parts of South America...
  66. Wu D, Wang Y, Liu J, Wang X, Zhang W. Two new compounds from the fruits of Buddleja lindleyana with neuroprotective effect. J Asian Nat Prod Res. 2012;14:342-7 pubmed publisher
    Two new triterpenoid glycosides, mimengosides H (1) and I (2), were isolated from the fruits of Buddleja lindleyana Fort. Their structures were determined by extensive spectroscopic methods...
  67. Gao Y, Li C, Zhang C, Xu Y, Tao B. [Study on the chemical constituent from Buddleja purdomii]. Zhong Yao Cai. 2004;27:339-41 pubmed
    To study the chemical constituents from Buddleja purdomii W. W. Smith.
  68. Lu J, Tu G, Zhao Y, Lv Y, Liu L, Wu Y. Structural determination of novel terpenes from Buddleia lindleyana. Magn Reson Chem. 2004;42:893-7 pubmed
    ..The complete 1H and 13C NMR assignments of the three compounds were carried out by using DEPT, COSY, HMQC and HMBC techniques. The stereochemistry of 1 and 3 was confirmed by single-crystal x-ray diffraction analysis...
  69. Yue L, Chen G, Sun W, Sun H. Phylogeography of Buddleja crispa (Buddlejaceae) and its correlation with drainage system evolution in southwestern China. Am J Bot. 2012;99:1726-35 pubmed publisher
    ..We here examine the population structure of Buddleja crispa, a dominant element of the dry, warm/hot river-valley communities, seeking to delimit the current ..