clerodendrum

Summary

Summary: A plant genus of the family Lamiaceae. Inerminosides (iridoid glycosides); colebroside A; STEROIDS; STEROLS; terpenoid glucosides; and abietane DITERPENES have been found in this genus.

Top Publications

  1. Chae S, Kim J, Kang K, Bu H, Lee Y, Seo Y, et al. Antioxidant activity of isoacteoside from Clerodendron trichotomum. J Toxicol Environ Health A. 2005;68:389-400 pubmed
    ..Taken together, these findings suggest that isoacteoside, isolated from C. trichotomum, possesses antioxidant properties...
  2. Panthong A, Kanjanapothi D, Taesotikul T, Wongcome T, Reutrakul V. Anti-inflammatory and antipyretic properties of Clerodendrum petasites S. Moore. J Ethnopharmacol. 2003;85:151-6 pubmed
    The methanol extract from Clerodendrum petasites S. Moore (CP extract) was assessed for anti-inflammatory and antipyretic activities on the experimental animal models...
  3. Nan H, Wu J, Zhang S. A new phenylethanoid glycoside from Clerodendrum inerme. Pharmazie. 2005;60:798-9 pubmed
    ..was isolated from the aerial parts of Clerodendrum inerme (L...
  4. Kotoky J, Dasgupta B, Deka N. Pharmacological studies of Clerodendron colebrookianum Walp, a potent hypotensive plant. Indian J Physiol Pharmacol. 2005;49:289-96 pubmed
    ..The leaves of the C. colebrookianum were practically found to be non-toxic...
  5. Gopal N, Sengottuvelu S. Hepatoprotective activity of Clerodendrum inerme against CCl4 induced hepatic injury in rats. Fitoterapia. 2008;79:24-6 pubmed
    The ethanolic extract of Clerodendrum inerme leaves were screened for its hepatoprotective activity in CCl4 (0.5 ml/kg, i.p) induced liver damage in Swiss albino rats at a dose of 200 mg /kg bw. The ethanolic extract of C...
  6. Pal D, Sannigrahi S, Mazumder U. Analgesic and anticonvulsant effects of saponin isolated from the leaves of Clerodendrum infortunatum Linn. in mice. Indian J Exp Biol. 2009;47:743-7 pubmed
    ..SN1 decreased the duration of seizures and gave protection in a dose dependent manner against leptazol-induced convulsions. The results suggest that saponin has significant analgesic and anticonvulsant effects...
  7. Vidya S, Krishna V, Manjunatha B, Mankani K, Ahmed M, Singh S. Evaluation of hepatoprotective activity of Clerodendrum serratum L. Indian J Exp Biol. 2007;45:538-42 pubmed
    ..The results when compared with the standard drug silymarin, revealed that the hepatoprotective activity of the constituent ursolic acid is significant as similar to the standard drug...
  8. Pandey R, Verma R, Gupta M. Neo-clerodane diterpenoids from Clerodendrum inerme. Phytochemistry. 2005;66:643-8 pubmed
    ..B and 14,15-dihydro-15 beta-methoxy-3-epicaryoptin, have been isolated from the hexane extract of the leaves of Clerodendrum inerme in addition to an epimeric mixture of 14,15-dihydro-15-hydroxy-3-epicaryoptin...
  9. Adeneye A, Adeleke T, Adeneye A. Hypoglycemic and hypolipidemic effects of the aqueous fresh leaves extract of Clerodendrum capitatum in Wistar rats. J Ethnopharmacol. 2008;116:7-10 pubmed
    ..carbohydrate metabolism, is treated in the African traditional phytotherapies with the cold water decoction of Clerodendrum capitatum (CC)...

More Information

Publications87

  1. Liu S, Zhu H, Zhang S, Zhang X, Yu Q, Xuan L. Abietane diterpenoids from Clerodendrum bungei. J Nat Prod. 2008;71:755-9 pubmed publisher
    ..1-5) along with three known diterpenoids (6-8) were isolated from an acetone-soluble extract of the roots of Clerodendrum bungei...
  2. Fan P, Huang W, Chiou L. Intractable chronic motor tics dramatically respond to Clerodendrum inerme (L) Gaertn. J Child Neurol. 2009;24:887-90 pubmed publisher
    ..anti-tic therapies, who showed dramatic improvement and remission after taking the crude leaf extract of Clerodendrum inerme (L) Gaertn. No side effects were observed during a follow-up of more than 2 years...
  3. Jatsa H, Ngo Sock E, Tchuem Tchuente L, Kamtchouing P. Evaluation of the in vivo activity of different concentrations of Clerodendrum umbellatum Poir against Schistosoma mansoni infection in mice. Afr J Tradit Complement Altern Med. 2009;6:216-21 pubmed
    b>Clerodendrum umbellatum Poir (Verbenaceae) is traditionally used in Cameroon for the treatment of many diseases including intestinal helminthiasis...
  4. Machumi F, Samoylenko V, Yenesew A, Derese S, Midiwo J, Wiggers F, et al. Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum. Nat Prod Commun. 2010;5:853-8 pubmed
    Chromatographic separation of the roots of a Kenyan medicinal plant, Clerodendrum eriophyllum, led to the isolation of ten abietane diterpenoids (1-10), one of which (1) was isolated for the first time from a natural source...
  5. Xu M, Shen L, Wang K, Du Q, Wang N. A new rearranged abietane diterpenoid from Clerodendrum kaichianum Hsu. J Asian Nat Prod Res. 2011;13:260-4 pubmed publisher
    ..1), was isolated from the stems of Clerodendrum kaichianum Hsu, together with four known diterpenoids...
  6. Abouzid S, Wahba H, Elshamy A, Cos P, Maes L, Apers S, et al. Antimicrobial activity of some Clerodendrum species from Egypt. Nat Prod Res. 2013;27:1032-6 pubmed publisher
    Chloroformic and methanolic extracts of four Clerodendrum species cultivated in Egypt were screened for antimicrobial activities...
  7. Zhou J, Zheng X, Yang Q, Liang Z, Li D, Yang X, et al. Optimization of ultrasonic-assisted extraction and radical-scavenging capacity of phenols and flavonoids from Clerodendrum cyrtophyllum Turcz leaves. PLoS ONE. 2013;8:e68392 pubmed publisher
    Ultrasonic-assisted extraction (UAE) was developed to extract phenolic and flavonoid antioxidants from Clerodendrum cyrtophyllum Turcz leaves. The optimal experimental parameters for antioxidant extraction from C...
  8. Mogwasi R, Zor S, Kariuki D, Getenga M, Nischwitz V. Sequential Extraction as Novel Approach to Compare 12 Medicinal Plants From Kenya Regarding Their Potential to Release Chromium, Manganese, Copper, and Zinc. Biol Trace Elem Res. 2018;182:407-422 pubmed publisher
    ..0 ± 0.1 mg/kg). Croton macrostachyus had the highest manganese level of 1630 ± 40 mg/kg while Clerodendrum myricoides had the lowest (80.2 ± 1.2 mg/kg). The highest level of chromium was in Solanum mauense (3...
  9. Waliullah T, Yeasmin A, Alam A, Islam W, Hassan P. In vitro Antimicrobial Study for Biological Evaluation of Clerodendrum infortunatum Linn. Recent Pat Antiinfect Drug Discov. 2015;10:98-104 pubmed
    ..This study serves as basis for further research to lead compounds to be isolated so that may be as a template for the implications of these results for bioactivity and drug discovery potential of herbal products are discussed. ..
  10. Somwong P, Suttisri R. Cytotoxic activity of the chemical constituents of Clerodendrum indicum and Clerodendrum villosum roots. J Integr Med. 2018;16:57-61 pubmed publisher
    The roots of two Thai medicinal plants, Clerodendrum indicum and Clerodendrum villosum are found in traditional medicine practices...
  11. Chae S, Kim J, Kang K, Bu H, Lee Y, Hyun J, et al. Antioxidant activity of jionoside D from Clerodendron trichotomum. Biol Pharm Bull. 2004;27:1504-8 pubmed
    ..However, it increased the activities of cellular antioxidant enzymes, superoxide dismutase and catalase. Taken together, these findings suggest that jionoside D, isolated from C. trichotomum, exhibits antioxidant properties. ..
  12. Pandey A, Pandey M, Tripathi B. Assessment of Air Pollution Tolerance Index of some plants to develop vertical gardens near street canyons of a polluted tropical city. Ecotoxicol Environ Saf. 2016;134:358-364 pubmed publisher
    ..39) followed by Aristolochia elegans (23.28), Thunbergia grandiflora (23.14), Quisqualis indica (22.42), and Clerodendrum splendens (22.36). However, lowest APTI value (8.75) was recorded for the species Hemidesmus indicus...
  13. Erukainure O, Mesaik A, Muhammad A, Chukwuma C, Manhas N, Singh P, et al. Flowers of Clerodendrum volubile exacerbate immunomodulation by suppressing phagocytic oxidative burst and modulation of COX-2 activity. Biomed Pharmacother. 2016;83:1478-1484 pubmed publisher
    ..extract and fractions [n-hexane (Hex), n-dichloromethane (DCM), ethyl acetate (EtOAc) and n-butanol (BuOH)] of Clerodendrum volubile flowers were investigated on whole blood phagocytic oxidative burst using luminol-amplified ..
  14. Babu N, Pandikumar P, Ignacimuthu S. Lysosomal membrane stabilization and anti-inflammatory activity of Clerodendrum phlomidis L.f., a traditional medicinal plant. J Ethnopharmacol. 2011;135:779-85 pubmed publisher
    b>Clerodendrum phlomidis L.f., is used to treat several inflammatory diseases and arthritis in Indian traditional system and folk medicine...
  15. Erukainure O, Mesaik M, Atolani O, Muhammad A, Chukwuma C, Islam M. Pectolinarigenin from the leaves of Clerodendrum volubile shows potent immunomodulatory activity by inhibiting T - cell proliferation and modulating respiratory oxidative burst in phagocytes. Biomed Pharmacother. 2017;93:529-535 pubmed publisher
    ..b>Clerodendrum volubile, a leafy vegetable is known for its folkloric applications in the treatments of several inflammatory ..
  16. Lekhooa M, Walubo A, du Plessis J, Matsabisa M. The development and use of a drug-induced immunosuppressed rat-model to screen Phela for mechanism of immune stimulation. J Ethnopharmacol. 2017;206:8-18 pubmed publisher
    Phela, is code name for a medicinal product made from four South African traditional medicinal plants (Clerodendrum glabrum E. Mey, Polianthes tuberosa (Linn.), Rotheca myricoides (Hochst.) Steane & Mabb. and Senna occidentalis (L...
  17. Kang D, Lee Y, Kim H, Lee Y, Lee H. Angiotensin converting enzyme inhibitory phenylpropanoid glycosides from Clerodendron trichotomum. J Ethnopharmacol. 2003;89:151-4 pubmed
    ..6 microg/ml, 505+/-26.7 microg/ml, respectively. These results suggest that the antihypertensive effect of Clerodendron trichotomum may be, at least in part, due to ACE inhibitory effect of phenylpropanoid glycosides. ..
  18. Lee J, Lee J, Sim S, Whang W, Kim C. Anti-asthmatic effects of phenylpropanoid glycosides from Clerodendron trichotomum leaves and Rumex gmelini herbes in conscious guinea-pigs challenged with aerosolized ovalbumin. Phytomedicine. 2011;18:134-42 pubmed publisher
    ..However, their anti-asthmatic effects were less than the reference drugs. These results indicated that caffeic acid and its glycosides (25mg/kg) have anti-asthmatic effect as the same manner with dexamethasone and disodium cromoglycate. ..
  19. Song H, Choi M, Ko M, Jeong J, Kim Y, Jang B, et al. Competitive inhibition of cytosolic Ca2+-dependent phospholipase A2 by acteoside in RBL-2H3 cells. Arch Pharm Res. 2012;35:905-10 pubmed publisher
    ..9 ?M and the inhibitory pattern appeared to be a competitive inhibitor. The above data, suggests that acteoside acts as a competitive inhibitor of cPLA(2) in RBL-2H3 cells. ..
  20. Mohan Maruga Raja M, Mishra S. Comprehensive review of Clerodendrum phlomidis: a traditionally used bitter. Zhong Xi Yi Jie He Xue Bao. 2010;8:510-24 pubmed
    b>Clerodendrum phlomidis Linn. f., (syn. Clerodendrum multiflorum (Burm.f) O. Kuntze, Volkameria multiflorum Burm. f...
  21. Mukungu N, Abuga K, Okalebo F, Ingwela R, Mwangi J. Medicinal plants used for management of malaria among the Luhya community of Kakamega East sub-County, Kenya. J Ethnopharmacol. 2016;194:98-107 pubmed publisher
    ..Arg are reported for the first time in the management of malaria. Although Clerodendrum johnstonii Oliv. (Jeruto et al., 2011) and Physalis peruviana L.(Ramadan et al...
  22. Passari A, Mishra V, Leo V, Gupta V, Singh B. Phytohormone production endowed with antagonistic potential and plant growth promoting abilities of culturable endophytic bacteria isolated from Clerodendrum colebrookianum Walp. Microbiol Res. 2016;193:57-73 pubmed publisher
    In this study, culturable endophytic bacterial isolates obtained from an ethnomedicinal plant Clerodendrum colebrookianum Walp...
  23. Asnake S, Teklehaymanot T, Hymete A, Erko B, Giday M. Evaluation of the antiplasmodial properties of selected plants in southern Ethiopia. BMC Complement Altern Med. 2015;15:448 pubmed publisher
    ..the aim of this study was to evaluate the safety and antimalarial activity of extracts of Ajuga integrifolia, Clerodendrum myricoides, Melia azedarach, Peponium vogelii and Premna schimperi, locally used by the Sidama people of ..
  24. Steane D, de Kok R, Olmstead R. Phylogenetic relationships between Clerodendrum (Lamiaceae) and other Ajugoid genera inferred from nuclear and chloroplast DNA sequence data. Mol Phylogenet Evol. 2004;32:39-45 pubmed
    Over the last two centuries the circumscription of the large, pan-tropical genus Clerodendrum (Lamiaceae) has changed frequently, as different authorities have added or removed taxa on the basis of various morphological characters...
  25. Lokesh D, Amitsankar D. Evaluation of mechanism for antihypertensive action of Clerodendrum colebrookianum Walp., used by folklore healers in north-east India. J Ethnopharmacol. 2012;143:207-12 pubmed publisher
    The present investigation was aimed to justify the pharmacological basis in traditional use of Clerodendrum colebrookianum as antihypertensive agent in north-east India...
  26. Erukainure O, Hafizur R, Choudhary M, Adhikari A, Mesaik A, Atolani O, et al. Anti-diabetic effect of the ethyl acetate fraction of Clerodendrum volubile: protocatechuic acid suppresses phagocytic oxidative burst and modulates inflammatory cytokines. Biomed Pharmacother. 2017;86:307-315 pubmed publisher
    The antidiabetic effects of the ethyl acetate (EtOAc) fraction of Clerodendrum volubile leaves was investigated in this study. EtOAc extract was also fractionated to isolate the active compounds...
  27. Nuaeissara S, Kondo S, Itharat A. Antimicrobial activity of the extracts from Benchalokawichian remedy and its components. J Med Assoc Thai. 2011;94 Suppl 7:S172-7 pubmed
    ..The remedy has been scientifically proved for antipyretic and antiseptic activities. However; the remedy and its components have not been fully studied for antimicrobial activity against pathogenic bacteria...
  28. Nutmakul T, Pattanapanyasat K, Soonthornchareonnon N, Shiomi K, Mori M, Prathanturarug S. Antiplasmodial activities of a Thai traditional antipyretic formulation, Bencha-Loga-Wichian: A comparative study between the roots and their substitutes, the stems. J Ethnopharmacol. 2016;193:125-132 pubmed publisher
    Bencha-Loga-Wichian (BLW) is a polyherbal antipyretic formulation that is comprised of Capparis micracantha, Clerodendrum indicum, Ficus racemosa, Harrisonia perforata, and Tiliacora triandra...
  29. Jadeja R, Thounaojam M, Ramani U, Devkar R, Ramachandran A. Anti-obesity potential of Clerodendron glandulosum.Coleb leaf aqueous extract. J Ethnopharmacol. 2011;135:338-43 pubmed publisher
    ..Clerodendron glandulosum.Coleb extract prevents adipocyte differentiation and visceral adiposity by down regulation of PPAR?-2 related genes and Lep expression thus validating its traditional therapeutic use in controlling obesity. ..
  30. Yang H, Hou A, Mei S, Sun H, Che C. Constituents of Clerodendrum bungei. J Asian Nat Prod Res. 2002;4:165-9 pubmed
    ..A (2), together with 12 known compounds (3-14), were isolated from the aerial parts of the medicinal plant Clerodendrum bungei...
  31. Min Y, Yim S, Bai K, Choi H, Jeong J, Song H, et al. The effects of apigenin-7-O-beta-D-glucuronopyranoside on reflux oesophagitis and gastritis in rats. Auton Autacoid Pharmacol. 2005;25:85-91 pubmed
    ..4. In summary, AGC is more potent than apigenin and omeprazole at inhibiting reflux oesophagitis and gastritis and may therefore be a promising drug for their treatment. ..
  32. Adia M, Emami S, Byamukama R, Faye I, Borg Karlson A. Antiplasmodial activity and phytochemical analysis of extracts from selected Ugandan medicinal plants. J Ethnopharmacol. 2016;186:14-19 pubmed publisher
    ..The air dried samples of Clerodendrum rotundifolium (leaves), Microglossa pyrifolia (leaves), Momordica foetida (leaves) and Zanthoxylum chalybeum (..
  33. Xiaojing W, Liang Z, Chen H, Zhao Z, Li P. Identification of Daqingye and Banlangen including crude drugs and decoction dregs from three plant species by normal light and fluorescence microscopy. Microsc Res Tech. 2013;76:774-82 pubmed publisher
    ..indigotica Fort. and two easily confused species, namely Baphicacanthus cusia (Nees) Bremek. and Clerodendrum cyrtophyllum Turcz., were investigated with normal light and fluorescence microscopy...
  34. Miller R, McConville M, Woodrow I. Cyanogenic glycosides from the rare Australian endemic rainforest tree Clerodendrum grayi (Lamiaceae). Phytochemistry. 2006;67:43-51 pubmed
    ..were isolated from the foliage of the rare Australian rainforest tree species Clerodendrum grayi (Lamiaceae)...
  35. Sakamoto R, Ito M, Kawakubo N. Contribution of pollinators to seed production as revealed by differential pollinator exclusion in Clerodendrum trichotomum (Lamiaceae). PLoS ONE. 2012;7:e33803 pubmed publisher
    ..Macroglossum pyrrhosticta, and Xylocopa appendiculata on fruit and seed production in Clerodendrum trichotomum by using a flower visitor barrier experiment with nets of specific mesh sizes...
  36. Wang P, Sun L, Tan J, Xu J, Guo F, Li Y. Two new glycosidated coumaramides from Clerodendron cyrtophyllum. Fitoterapia. 2012;83:1494-9 pubmed publisher
    ..The isolated new compound 2 was assayed for the inhibition of the NF-?B pathway and showed potent activity in inhibiting NF-?B which its IC(50) values was found to be 24.9 nM...
  37. Wang W, Xiong J, Tang Y, Zhu J, Li M, Zhao Y, et al. Rearranged abietane diterpenoids from the roots of Clerodendrum trichotomum and their cytotoxicities against human tumor cells. Phytochemistry. 2013;89:89-95 pubmed publisher
    The roots of the medicinal ornamental plant Clerodendrum trichotomum yielded a series of rearranged abietane diterpenoids, including three 17(15?16)-abeo-abietane (1-3) and three 17(15?16),18(4?3)-diabeo-abietane (4-6) derivatives...
  38. Jadeja R, Thounaojam M, Ansarullah -, Jadav S, Patel M, Patel D, et al. Toxicological evaluation and hepatoprotective potential of Clerodendron glandulosum.Coleb leaf extract. Hum Exp Toxicol. 2011;30:63-70 pubmed publisher
    ..CG extract exhibits potent hepatoprotective activity against CCl(4)-induced hepatic damage but does not exhibit any toxic manifestations...
  39. Surapaneni S, Prakash T, Ansari M, Manjunath P, Kotresha D, Goli D. Study on cerebroprotective actions of Clerodendron glandulosumleaves extract against long term bilateral common carotid artery occlusion in rats. Biomed Pharmacother. 2016;80:87-94 pubmed publisher
    ..Infarct size and histopathological changes were observed in treated groups. ..
  40. Wahba H, Abouzid S, Sleem A, Apers S, Pieters L, Shahat A. Chemical and biological investigation of some Clerodendrum species cultivated in Egypt. Pharm Biol. 2011;49:66-72 pubmed publisher
    Phytochemical investigation of Clerodendrum chinense (Osbeck) Mabberley (Lamiaceae) cultivated in Egypt and evaluation for anti-inflammatory, analgesic, and antipyretic effects of the methanol and chloroform extracts of Clerodendrum ..
  41. Parveen M, Khanam Z, Ali M, Rahman S. A novel lupene-type triterpenic glucoside from the leaves of Clerodendrum inerme. Nat Prod Res. 2010;24:167-76 pubmed publisher
    ..three known phytoconstituents: n-octacosane, friedelin and beta-amyrin, has been isolated from the leaves of Clerodendrum inerme (L.) Gaertn. (Verbenaceae)...
  42. Kanchanapoom T, Chumsri P, Kasai R, Otsuka H, Yamasaki K. A new iridoid diglycoside from Clerodendrum chinense. J Asian Nat Prod Res. 2005;7:269-72 pubmed
    A new iridoid diglucoside, 5-O-beta-glucopyranosyl-harpagide, has been isolated from the aerial part of Clerodendrum chinense together with three known iridoid glucosides and six known cyclohexylethanoids...
  43. Zailani A, Balogun E, Adebayo J. Ethanolic extract of Clerodendrum violaceum Gürke leaves enhances kidney function in mouse model of malaria. Indian J Exp Biol. 2009;47:349-54 pubmed
    ..The results suggest that the ethanolic extract of C. violaceum leaves does not adversely affect kidney function at the dose used in traditional medicine for the treatment of malaria but rather enhances it...
  44. Yu A. [Studies on the chemical constituents of the volatiles of Clerodendron bungei]. Zhongguo Zhong Yao Za Zhi. 2004;29:157-9 pubmed
    ..To analyse chemical constituents of the volatiles of Clerodendron bungei...
  45. Pandey R, Verma R, Gupta M. High-performance thin-layer chromatographic method for quantitative determination of 4alpha-methyl-24beta-ethyl-5alpha-cholesta-14,25-dien-3beta-ol, 24beta-ethylcholesta-5,9(11),22E-trien-3beta-ol, and betulinic acid in Clerodendrum inerme. J Sep Sci. 2007;30:2086-91 pubmed
    ..1) and 24beta-ethylcholesta-5,9(11),22E-trien-3beta-ol (2), and a triterpene, betulinic acid (3), in Clerodendrum inerme extract. The method employed HPTLC plates precoated with silica gel 60F(254 )as the stationary phase...
  46. Chae S, Kang K, Kim J, Hyun J, Kang S. Trichotomoside: a new antioxidative phenylpropanoid glycoside from Clerodendron trichotomum. Chem Biodivers. 2006;3:41-8 pubmed
    ..The radical-scavenging activity of 1 was found to protect the viability of Chinese hamster lung fibroblasts (V79-4 cells) exposed to H2O2 and gamma-irradiation...
  47. Xu M, Wang S, Jia O, Zhu Q, Shi L. Bioactive Diterpenoids from Clerodendrum kiangsiense. Molecules. 2016;21:86 pubmed publisher
    ..8), was isolated from the hydroalcoholic extract of the herb of Clerodendrum kiangsiense along with seven known diterpenoids (1-7)...
  48. Faiella L, Temraz A, Cotugno R, De Tommasi N, Braca A. Diterpenes and phenylpropanoids from Clerodendrum splendens. Planta Med. 2013;79:1341-7 pubmed publisher
    Four new clerodane diterpenes (1-4) and one new phenylpropanoid (5) have been isolated from Clerodendrum splendens aerial parts, together with nine known compounds...
  49. Kouakou K, Schepetkin I, Jun S, Kirpotina L, Yapi A, Khramova D, et al. Immunomodulatory activity of polysaccharides isolated from Clerodendrum splendens: beneficial effects in experimental autoimmune encephalomyelitis. BMC Complement Altern Med. 2013;13:149 pubmed publisher
    Extracts of leaves from Clerodendrum have been used for centuries to treat a variety of medicinal problems in tropical Africa...
  50. Mire S. 'The child that tiire doesn't give you, God won't give you either.' The role of Rotheca myricoides in Somali fertility practices. Anthropol Med. 2016;23:311-331 pubmed
    ..It concludes that fertility rituals are part of a wider context of interaction with sacred landscapes, objects and archaeological sites, often associated with past legends in the Horn of Africa...
  51. Li Y, Huang R, Zheng X. [The progress of studying C. spicatus]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002;22:470-2 pubmed
  52. Hayelom K, Mekbeb A, Eyasu M, Wondwossen E, Kelbesa U. Methanolic effect of Clerodendrum myricoides root extract on blood, liver and kidney tissues of mice. Afr Health Sci. 2012;12:489-97 pubmed
    The present study deals with the toxicological investigations of chronic treatment with methanol root extract of Clerodendrum myricoides on body weight, hematological and biochemical parameters, and liver and kidney tissue sections...
  53. Sannigrahi S, Mazumder U, Pal D, Mishra S. Terpenoids of methanol extract of Clerodendrum infortunatum exhibit anticancer activity against Ehrlich's ascites carcinoma (EAC) in mice. Pharm Biol. 2012;50:304-9 pubmed publisher
    b>Clerodendrum infortunatum Linn. is a widely used plant in the Indian indigenous system of medicine for the treatment of tumors.
  54. Li Y, Li J, Li P, Tu P. [Isolation and characterization of phenylethanoid glycosides from Clerodendron bungei]. Yao Xue Xue Bao. 2005;40:722-7 pubmed
    ..To study the chemical constituents from Clerodendron bungei Steud...
  55. Ono M, Furusawa C, Matsumura K, Noguchi S, Yasuda S, Okawa M, et al. A new diterpenoid from the leaves of Clerodendron trichotomum. J Nat Med. 2013;67:404-9 pubmed publisher
    ..Their chemical structures were characterized on the basis of spectroscopic data and X-ray analysis. In addition, their antioxidant activities were evaluated using four different analyses...
  56. Mohan Maruga Raja M, Mishra S. Isolation, characterization and thin-layer chromatography method development of clerosterol palmityl ester: a chemical marker for standardization of leaves of Clerodendrum phlomidis. Zhong Xi Yi Jie He Xue Bao. 2012;10:109-13 pubmed
    ..Clerosterol palmityl ester (CPE) is a unique clerosterol derivative isolated and characterized from the leaves of Clerodendrum phlomidis...
  57. Mizusawa L, Kaneko S, Hasegawa M, Isagi Y. Development of nuclear SSRs for the insular shrub Clerodendrum izuinsulare (Verbenaceae) and the widespread C. trichotomum. Am J Bot. 2011;98:e333-6 pubmed publisher
    Nuclear microsatellite primers were developed in the insular shrub Clerodendrum izuinsulare and the closely related widespread C...
  58. Gantait A, Roy P, Nema N, Dutta P, Mukherjee P. A validated method for standardization of the bark of Clerodendron serratum. Nat Prod Commun. 2010;5:863-6 pubmed
    ..HPTLC was used to quantify oleanolic acid in the extract. Percentage content of oleanolic acid in the methanolic extract was determined as 1.2% in contrast to the raw material at 0.058 % (Percentage yield of the extract 4.8%)...
  59. Ali M, Ahmed Z, Ali M, Ngoupayo J. Formadienoate-A and B: two new long chained feruloyl esters from Clerodendrum formicarum (Lamiaceae) of Cameroon. Nat Prod Commun. 2010;5:919-22 pubmed
    The ethanol extract of the leaves of Clerodendrum formicarum Gürke, a Lameacious plant of Cameroon, afforded two new long-chained esters named formadienoate-A (1) and B (2) along with two known constituents which have been obtained for ..
  60. Jadeja R, Thounaojam M, Dandekar D, Devkar R, Ramachandran A. Clerodendron glandulosum.Coleb extract ameliorates high fat diet/fatty acid induced lipotoxicity in experimental models of non-alcoholic steatohepatitis. Food Chem Toxicol. 2010;48:3424-31 pubmed publisher
    ..These in vivo and in vitro studies suggest that CG extract has the potential of preventing high fat/fatty acid induced NASH...
  61. Jadeja R, Thounaojam M, Devkar R, Ramachandran A. Clerodendron glandulosum.Coleb extract prevents in vitro human LDL oxidation and oxidized LDL induced apoptosis in human monocyte derived macrophages. Food Chem Toxicol. 2011;49:1195-202 pubmed publisher
    ..This is the first report on the protective role of CG extract on two key events of atherosclerosis portending its possible therapeutic use as an anti-atherogenic herbal medicine...
  62. Park M, Kim H. Anti-inflammatory constituents isolated from Clerodendron trichotomum Tunberg Leaves (CTL) inhibits pro-inflammatory gene expression in LPS-stimulated RAW 264.7 macrophages by suppressing NF-kappaB activation. Arch Pharm Res. 2007;30:755-60 pubmed
    ..These results suggest that CTL inhibits the expression of the pro-inflammation gene through the inhibition of NF-kappaB dependent pathway in RAW 264.7 cells...
  63. Renju G, Manoharan S, Balakrishnan S, Senthil N. Chemopreventive and antilipidperoxidative potential of Clerodendron inerme (L) Gaertn in 7,12-dimethylbenz(a)anthracene induced skin carcinogenesis in Swiss albino mice. Pak J Biol Sci. 2007;10:1465-70 pubmed
    ..The present study thus demonstrated the chemopreventive and antilipidperoxidative efficacy of CiELet in DMBA induced mouse skin carcinogenesis...
  64. Kim K, Kim S, Jung M, Ham I, Whang W. Anti-inflammatory phenylpropanoid glycosides from Clerodendron trichotomum leaves. Arch Pharm Res. 2009;32:7-13 pubmed publisher
    ..80% methanol fraction and acteoside had the activity...
  65. Gao L, Wei X, He Y. [Studies on chemical constituents in leafs of Clerodendron fragrans]. Zhongguo Zhong Yao Za Zhi. 2003;28:948-51 pubmed
    ..To separate and identify the constituents from Clerodendron fragrans...
  66. Kim S, Cho S, Moon H. Anti-complement activity of isolated compounds from the roots of Clerodendrum bungei Steud. Phytother Res. 2010;24:1720-3 pubmed publisher
    ..activity of natural diterpenes, chromatographic separation of the acetone-soluble fraction from the roots of Clerodendrum bungei (Verbenaceae) led to the isolation of five diterpenoids. An acetone-soluble extract of the roots of C...
  67. Ali M, Ahmed Z, Ali M, Ngoupayo J. Two new aromatic acids from Clerodendrum formicarum Gurke (Lamiaceae) of Cameroon. J Asian Nat Prod Res. 2010;12:894-8 pubmed publisher
    The ethanolic extract of the leaves of Clerodendrum formicarum, a Lameacious plant of Cameroon, afforded two new salicylic acid derivatives named formoic acids A and B along with four known constituents which have been obtained for the ..
  68. Ray S, Kundu L, Goswami S, Roy G, Chatterjee S, Dutta S, et al. Metaphase arrest and delay in cell cycle kinetics of root apical meristems and mouse bone marrow cells treated with leaf aqueous extract of Clerodendrum viscosum Vent. Cell Prolif. 2013;46:109-17 pubmed publisher
    To study cell cycle delay and metaphase arresting activity of leaf aqueous extract of Clerodendrum viscosum Vent. (LAECV) in root apical meristems and mouse bone marrow cells.
  69. Devi R, Sharma D. Hypolipidemic effect of different extracts of Clerodendron colebrookianum Walp in normal and high-fat diet fed rats. J Ethnopharmacol. 2004;90:63-8 pubmed
    ..Therefore, it was concluded that the leaves of CC have definite cardioprotective potentiality, and there is a valid scientific basis for consuming it for better health in NE region of India...
  70. Jadeja R, Thounaojam M, Jain M, Devkar R, Ramachandran A. Clerodendron glandulosum.Coleb leaf extract attenuates in vitro macrophage differentiation and expression of VCAM-1 and P-selectin in thoracic aorta of atherogenic diet fed rats. Immunopharmacol Immunotoxicol. 2012;34:443-53 pubmed publisher
    ..It can be concluded from the present study that, CG extract is capable of controlling induction of experimental atherosclerosis and warrants further scrutiny at the clinical level as a possible therapeutic agent...
  71. Pandey R, Verma R, Singh S, Gupta M. 4alpha-methyl-24beta-ethyl-5alpha-cholesta-14,25-dien-3beta-ol and 24beta-ethylcholesta-5, 9(11), 22E-trien-3beta-ol, sterols from Clerodendrum inerme. Phytochemistry. 2003;63:415-20 pubmed
    From the aerial parts of Clerodendrum inerme, two new sterols (4alpha-methyl-24beta-ethyl-5alpha-cholesta-14, 25-dien-3beta-ol and 24beta-ethylcholesta-5, 9(11), 22E-trien-3beta-ol) and a new aliphatic ketone (11-pentacosanone) were ..
  72. Jadeja R, Thounaojam M, Singh T, Devkar R, Ramachandran A. Traditional uses, phytochemistry and pharmacology of Clerodendron glandulosum Coleb--a review. Asian Pac J Trop Med. 2012;5:1-6 pubmed publisher
  73. Zhu Y, Hu Y, Cheng N, Cen Y. [Study on the chemical constituents of Clerodendron philippinum var. simplex]. Zhong Yao Cai. 2013;36:67-9 pubmed
    ..To study the chemical constituents of Clerodendron philippinum var. simplex...
  74. Adamu M, Naidoo V, Eloff J. Some southern African plant species used to treat helminth infections in ethnoveterinary medicine have excellent antifungal activities. BMC Complement Altern Med. 2012;12:213 pubmed publisher
    ..g. benzimidazoles also have good antifungal activity we examined the antifungal activity of extracts of 13 plant species used in southern Africa to treat gastrointestinal helminth infections in livestock and in man...
  75. Adamu M, Naidoo V, Eloff J. Efficacy and toxicity of thirteen plant leaf acetone extracts used in ethnoveterinary medicine in South Africa on egg hatching and larval development of Haemonchus contortus. BMC Vet Res. 2013;9:38 pubmed publisher
    ..Cytotoxicity of these extracts was also evaluated using the MTT cellular assay...
  76. Krishna Kumari G, Balachandran J, Aravind S, Ganesh M. Antifeedant and growth inhibitory effects of some neo-clerodane diterpenoids isolated from Clerodendron species (Verbenaceae) on Earias vitella and Spodoptera litura. J Agric Food Chem. 2003;51:1555-9 pubmed
    ..litura. All of the tested compounds, namely, clerodendrin B, 3-epicaryoptin, clerodendrin C, 15-hydroxyepicaryoptin, clerodendrin B acetate, and clerodin, showed good insect growth inhibitory activity even at lower concentrations...
  77. Srivastava A, Gupta R, Verma H. Micropropagation of Clerodendrum aculeatum through adventitious shoot induction and production of consistent amount of virus resistance inducing protein. Indian J Exp Biol. 2004;42:1200-7 pubmed
    Rapid micropropagation through adventitious shoot induction from in vitro raised leaf explants of Clerodendrum aculeatum (Verbenaceae), was successfully achieved for the first time...
  78. Shahabuddin S, Munikishore R, Trimurtulu G, Gunasekar D, Devillee A, Bodo B. Two new chalcones from the flowers of Clerodendrum inerme. Nat Prod Commun. 2013;8:459-60 pubmed
    ..1) and 3,2'-dihydroxy-3',4'-dimethoxychalcone (2), were isolated from the flowers of Clerodendrum inerme (L.) Gaertn together with two known flavones, 7-O-methylwogonin (3) and eucalyptin (4)...