lamiaceae

Summary

Summary: The mint plant family. They are characteristically aromatic, and many of them are cultivated for their oils. Most have square stems, opposite leaves, and two-lipped, open-mouthed, tubular corollas (united petals), with five-lobed, bell-like calyxes (united sepals).

Top Publications

  1. Ntalli N, Ferrari F, Giannakou I, Menkissoglu Spiroudi U. Phytochemistry and nematicidal activity of the essential oils from 8 Greek Lamiaceae aromatic plants and 13 terpene components. J Agric Food Chem. 2010;58:7856-63 pubmed publisher
    ..The EOs were isolated from eight Greek Lamiaceae species: Melissa officinalis , Sideritis clandestina , Origanum dictamnus , Ocimum basilicum , Mentha pulegium , ..
  2. Agostini G, Echeverrigaray S, Souza Chies T. A preliminary phylogeny of the genus Cunila D. Royen ex L. (Lamiaceae) based on ITS rDNA and trnL-F regions. Mol Phylogenet Evol. 2012;65:739-47 pubmed publisher
  3. Kanaoka M, Kawano N, Matsubara Y, Susaki D, Okuda S, Sasaki N, et al. Identification and characterization of TcCRP1, a pollen tube attractant from Torenia concolor. Ann Bot. 2011;108:739-47 pubmed publisher
    ..This pollen tube attraction is highly species specific, and a group of small secreted proteins, TfCRPs, are necessary for this process in Torenia fournieri...
  4. Burk D, Senechal Willis P, Lopez L, Hogue B, Daskalova S. Suppression of lipopolysaccharide-induced inflammatory responses in RAW 264.7 murine macrophages by aqueous extract of Clinopodium vulgare L. (Lamiaceae). J Ethnopharmacol. 2009;126:397-405 pubmed publisher
    ..g. gastric ulcers, diabetes, and cancer)...
  5. Ribeiro V, Dos Santos J, Bordignon S, Apel M, Henriques A, von Poser G. Acaricidal properties of the essential oil from Hesperozygis ringens (Lamiaceae) on the cattle tick Riphicephalus (Boophilus) microplus. Bioresour Technol. 2010;101:2506-9 pubmed publisher
    Hesperozygis ringens (Benth.) Epling (Lamiaceae) is a strongly aromatic plant employed popularly for its antiparasitic properties. The leaves afforded 4% of essential oil constituted mainly by pulegone (86%)...
  6. Stagos D, Portesis N, Spanou C, Mossialos D, Aligiannis N, Chaita E, et al. Correlation of total polyphenolic content with antioxidant and antibacterial activity of 24 extracts from Greek domestic Lamiaceae species. Food Chem Toxicol. 2012;50:4115-24 pubmed publisher
    b>Lamiaceae family species are considered important because of their use in folk medicine, culinary and flavouring throughout the world. Their interesting bioactivities are attributed mainly to essential oils, polyphenols and terpenes...
  7. Drew B, Sytsma K. Phylogenetics, biogeography, and staminal evolution in the tribe Mentheae (Lamiaceae). Am J Bot. 2012;99:933-53 pubmed publisher
    The mint family (Lamiaceae) is the sixth largest family of flowering plants, with the tribe Mentheae containing about a third of the species...
  8. Martinez Vazquez M, Estrada Reyes R, Martínez Laurrabaquio A, López Rubalcava C, Heinze G. Neuropharmacological study of Dracocephalum moldavica L. (Lamiaceae) in mice: sedative effect and chemical analysis of an aqueous extract. J Ethnopharmacol. 2012;141:908-17 pubmed publisher
    ..Despite its intensive use no literature reported neuropharmacological studies on Dracocephalum moldavica as yet...
  9. Li Y, Peng S, Chen H, Zhang F, Xu P, Xie J, et al. Oral administration of patchouli alcohol isolated from Pogostemonis Herba augments protection against influenza viral infection in mice. Int Immunopharmacol. 2012;12:294-301 pubmed publisher
    ..Thus, oral administration of PA appears to be able to augment protection against IFV infection in mice via enhancement of host immune responses, and attenuation of systemic and pulmonary inflammatory responses...

More Information

Publications80

  1. Ravindran R, Juliet S, Sunil A, Kumar K, Nair S, Amithamol K, et al. Eclosion blocking effect of ethanolic extract of Leucas aspera (Lamiaceae) on Rhipicephalus (Boophilus) annulatus. Vet Parasitol. 2011;179:287-90 pubmed publisher
    ..L. aspera extract also produced complete failure of eclosion of eggs from the treated ticks even at lower dilutions of the extract...
  2. Kalaivani K, Senthil Nathan S, Murugesan A. Biological activity of selected Lamiaceae and Zingiberaceae plant essential oils against the dengue vector Aedes aegypti L. (Diptera: Culicidae). Parasitol Res. 2012;110:1261-8 pubmed publisher
    ..The results achieved suggest that, in addition to their medicinal activities, Lamiaceae and Zingiberaceae plant extracts may also serve as a natural larvicidal agent.
  3. Berdowska I, Zielinski B, Fecka I, Kulbacka J, Saczko J, Gamian A. Cytotoxic impact of phenolics from Lamiaceae species on human breast cancer cells. Food Chem. 2013;141:1313-21 pubmed publisher
    ..It might be concluded that the tested phenolics exhibited more beneficial properties when they were applied in the form of extracts comprising their mixtures. ..
  4. Sarac N, Ugur A. The in vitro antimicrobial activities of the essential oils of some Lamiaceae species from Turkey. J Med Food. 2009;12:902-7 pubmed publisher
    ..In fact, essential oils of some plants belonging to the same taxa but collected from different localities showed different levels of antimicrobial activities...
  5. De Martino L, De Feo V, Nazzaro F. Chemical composition and in vitro antimicrobial and mutagenic activities of seven Lamiaceae essential oils. Molecules. 2009;14:4213-30 pubmed publisher
    ..The essential oils of seven Lamiaceae species were analyzed by gas chromatography-mass spectrometry and assayed for their antibacterial, antifungal ..
  6. Estrada Reyes R, Martinez Vazquez M, Gallegos Solís A, Heinze G, Moreno J. Depressant effects of Clinopodium mexicanum Benth. Govaerts (Lamiaceae) on the central nervous system. J Ethnopharmacol. 2010;130:1-8 pubmed publisher
    The decoction of leaves of Clinopodium mexicanum Benth. Goaverts (Lamiaceae), commonly known as "Toronjil de Monte", is used in the Mexican traditional medicine to induce sleep, as well as sedative and analgesic remedy.
  7. Hossain M, Rai D, Brunton N, Martin Diana A, Barry Ryan C. Characterization of phenolic composition in Lamiaceae spices by LC-ESI-MS/MS. J Agric Food Chem. 2010;58:10576-81 pubmed publisher
    A total of 38 phenolic compounds in the solid/liquid extracts of five Lamiaceae spices, rosemary, oregano, sage, basil, and thyme, were identified in the present study using LC-ESI-MS/MS...
  8. Maggi F, Barboni L, Caprioli G, Papa F, Ricciutelli M, Sagratini G, et al. HPLC quantification of coumarin in bastard balm (Melittis melissophyllum L., Lamiaceae). Fitoterapia. 2011;82:1215-21 pubmed publisher
    ..Furthermore, coumarin was found to be useful as marker compound to differentiate the bastard balm subspecies occurring in Italy, since the subsp. albida contained a much lower content of this molecule (19-34 mg/kg)...
  9. Li Y, Xian Y, Ip S, Su Z, Su J, He J, et al. Anti-inflammatory activity of patchouli alcohol isolated from Pogostemonis Herba in animal models. Fitoterapia. 2011;82:1295-301 pubmed publisher
    ..These results suggest that PA possesses potent anti-inflammatory activity, which may be mediated, at least in part, by down-regulating the mRNA expression of a panel of inflammatory mediators including TNF-?, IL-1?, iNOS and COX-2...
  10. Li Y, Liang H, Chen H, Tan L, Yi Y, Qin Z, et al. Anti-Candida albicans activity and pharmacokinetics of pogostone isolated from Pogostemonis Herba. Phytomedicine. 2012;20:77-83 pubmed publisher
    ..This study demonstrated the potential of PO as a promising candidate for the treatment of Candida infections, particularly for vulvovaginal candidiasis...
  11. Meng H, Zhang M. Diversification of plant species in arid Northwest China: species-level phylogeographical history of Lagochilus Bunge ex Bentham (Lamiaceae). Mol Phylogenet Evol. 2013;68:398-409 pubmed publisher
    ..We suggest that diversification is most likely the result of the past fragmentation due to aridification; the expansion of the range of species along with the deserts was an adaptation to dry and cold environments during the Quaternary...
  12. Grayer R, Eckert M, Veitch N, Kite G, Marin P, Kokubun T, et al. The chemotaxonomic significance of two bioactive caffeic acid esters, nepetoidins A and B, in the Lamiaceae. Phytochemistry. 2003;64:519-28 pubmed
    A survey of leaf surface constituents in the family Lamiaceae using HPLC with diode array detection revealed the presence of two characteristic phenolic compounds in many species...
  13. Bozin B, Mimica Dukic N, Simin N, Anackov G. Characterization of the volatile composition of essential oils of some lamiaceae spices and the antimicrobial and antioxidant activities of the entire oils. J Agric Food Chem. 2006;54:1822-8 pubmed
    ..A significant rate of antifungal activity of all of the examined essential oils was also exhibited...
  14. Marino M, Bersani C, Comi G. Impedance measurements to study the antimicrobial activity of essential oils from Lamiaceae and Compositae. Int J Food Microbiol. 2001;67:187-95 pubmed
    ..The data obtained from the study of the bactericidal effect of oregano essential oil indicated that the major part of the species was irreversibly inactivated, i.e. they could not be revived by enrichment...
  15. Cetin H, Cinbilgel I, Yanikoglu A, Gokceoglu M. Larvicidal activity of some Labiatae (Lamiaceae) plant extracts from Turkey. Phytother Res. 2006;20:1088-90 pubmed
    Ethanol extracts of the aerial parts from five Labiatae (Lamiaceae) species, obtained from Antalya, Turkey, were tested for larvicidal activity against the house mosquito Culex pipiens L. (Diptera: Culicidae) under laboratory conditions...
  16. Zgórka G, Głowniak K. Variation of free phenolic acids in medicinal plants belonging to the Lamiaceae family. J Pharm Biomed Anal. 2001;26:79-87 pubmed
    Ten species belonging to the family Lamiaceae and representing the most popular medicinal plants used in Polish phytotherapy were examined for the content of free phenolic acids (PhAs)...
  17. Lopez V, Akerreta S, Casanova E, García Mina J, Cavero R, Calvo M. In vitro antioxidant and anti-rhizopus activities of Lamiaceae herbal extracts. Plant Foods Hum Nutr. 2007;62:151-5 pubmed
    Eighty-eight extracts of different polarity obtained from 18 Lamiaceae medicinal and aromatic plants were screened for their antioxidant and antifungal properties...
  18. Karanika M, Komaitis M, Aggelis G. Effect of aqueous extracts of some plants of Lamiaceae family on the growth of Yarrowia lipolytica. Int J Food Microbiol. 2001;64:175-81 pubmed
    Aqueous extracts of some plants belonging to the Lamiaceae family (Sideritis montana, Origanum dictamnus, Mentha piperita, Rosmarinus officinallis and Origanum marjorana) caused an important increase of the lag time of Yarrowia ..
  19. Orhan I, Aslan M. Appraisal of scopolamine-induced antiamnesic effect in mice and in vitro antiacetylcholinesterase and antioxidant activities of some traditionally used Lamiaceae plants. J Ethnopharmacol. 2009;122:327-32 pubmed publisher
    ..Teucrium polium was reported to be used in Anatolia for memory-enhancement in a very old book written by an Ottoman herbalist-physician...
  20. Liu S, Jiang S, Wu Z, Lv L, Zhang J, Zhu Z, et al. Identification of inhibitors of the HIV-1 gp41 six-helix bundle formation from extracts of Chinese medicinal herbs Prunella vulgaris and Rhizoma cibotte. Life Sci. 2002;71:1779-91 pubmed
    ..These results suggest that tannin may be one of major inhibitors of the HIV-1 gp41 six-helix bundle formation in the herb extracts and that tannin may inhibit HIV-1 entry by disrupting the gp41 six-helix bundle formation...
  21. Dorman H, Bachmayer O, Koşar M, Hiltunen R. Antioxidant properties of aqueous extracts from selected lamiaceae species grown in Turkey. J Agric Food Chem. 2004;52:762-70 pubmed
    ..All the extracts contained Folin-Ciocalteu reagent-reactive substances, which was confirmed by the presence of polar phenolic analytes (i.e., hydroxybenzoates, hydroxycinnamates, and flavonoids)...
  22. Vardar Unlu G, Candan F, Sokmen A, Daferera D, Polissiou M, Sokmen M, et al. Antimicrobial and antioxidant activity of the essential oil and methanol extracts of Thymus pectinatus Fisch. et Mey. Var. pectinatus (Lamiaceae). J Agric Food Chem. 2003;51:63-7 pubmed
    ..In conclusion, the results presented here show that T. pectinatus essential oil could be considered as a natural antimicrobial and antioxidant source...
  23. Rahman M, Sadhu S, Hasan C. Preliminary antinociceptive, antioxidant and cytotoxic activities of Leucas aspera root. Fitoterapia. 2007;78:552-5 pubmed
    ..The extract showed a significant free radical scavenging activity with an IC(50) of 8 microg/ml. The extract showed significant lethality to brine shrimp with an LC(50) value...
  24. Liu J, Wang L, Geng Y, Wang Q, Luo L, Zhong Y. Genetic diversity and population structure of Lamiophlomis rotata (Lamiaceae), an endemic species of Qinghai-Tibet Plateau. Genetica. 2006;128:385-94 pubmed
    Lamiophlomis rotata (Lamiaceae), a perennial medicinal herb, is endemic to the Qinghai-Tibet Plateau. A total of 188 individuals from eight natural populations of L...
  25. Nolkemper S, Reichling J, Stintzing F, Carle R, Schnitzler P. Antiviral effect of aqueous extracts from species of the Lamiaceae family against Herpes simplex virus type 1 and type 2 in vitro. Planta Med. 2006;72:1378-82 pubmed
    Aqueous extracts from species of the Lamiaceae family were examined for their antiviral activity against Herpes simplex virus (HSV)...
  26. Kivilompolo M, Hyötyläinen T. Comprehensive two-dimensional liquid chromatography in analysis of Lamiaceae herbs: characterisation and quantification of antioxidant phenolic acids. J Chromatogr A. 2007;1145:155-64 pubmed
    ..was developed for extracting phenolic acids from basil, oregano, rosemary, sage, spearmint and thyme of the Lamiaceae family. The results were compared with results obtained by conventional solvent extraction techniques...
  27. Peterson C, Nemetz L, Jones L, Coat J. Behavioral activity of catnip (Lamiaceae) essential oil components to the German cockroach (Blattodea: Blattellidae). J Econ Entomol. 2002;95:377-80 pubmed
    ..Antennectomized insects showed no response to concentrations that were active against intact insects...
  28. Meimberg H, Abele T, Bräuchler C, McKay J, Pérez de Paz P, Heubl G. Molecular evidence for adaptive radiation of Micromeria Benth. (Lamiaceae) on the Canary Islands as inferred from chloroplast and nuclear DNA sequences and ISSR fingerprint data. Mol Phylogenet Evol. 2006;41:566-78 pubmed
    ..The genus Micromeria (Lamiaceae, Mentheae) includes 16 species and 13 subspecies in Macaronesia...
  29. Tan P, Nyasse B, Dimo T, Mezui C. Gastric cytoprotective anti-ulcer effects of the leaf methanol extract of Ocimum suave (Lamiaceae) in rats. J Ethnopharmacol. 2002;82:69-74 pubmed
    The anti-ulcerogenic potential of the leaf methanol extract of Ocimum suave (Lamiaceae) was investigated using four methods of gastric lesion induction in experimental Wistar rats (150-200 g): (1) HCl/ethanol-induced gastric lesions, (2) ..
  30. Geuenich S, Goffinet C, Venzke S, Nolkemper S, Baumann I, Plinkert P, et al. Aqueous extracts from peppermint, sage and lemon balm leaves display potent anti-HIV-1 activity by increasing the virion density. Retrovirology. 2008;5:27 pubmed publisher
    Aqueous extracts from leaves of well known species of the Lamiaceae family were examined for their potency to inhibit infection by human immunodeficiency virus type 1 (HIV-1).
  31. Matkowski A, Piotrowska M. Antioxidant and free radical scavenging activities of some medicinal plants from the Lamiaceae. Fitoterapia. 2006;77:346-53 pubmed
    Antioxidative effects of methanolic extracts from six wild European Lamiaceae species have been studied with the use of three in vitro assays...
  32. Cruzan M. Population size and fragmentation thresholds for the maintenance of genetic diversity in the herbaceous endemic Scutellaria montana (Lamiaceae). Evolution. 2001;55:1569-80 pubmed
    ..This study demonstrates that the regional distribution of populations can be an important factor for the long-term maintenance of genetic variation...
  33. Kwon Y, Vattem D, Shetty K. Evaluation of clonal herbs of Lamiaceae species for management of diabetes and hypertension. Asia Pac J Clin Nutr. 2006;15:107-18 pubmed
    In the current study, we screened 7 clonal lines from single seed phenotypes of Lamiaceae family for the inhibition of alpha-amylase, alpha-glucosidase and angiotensin converting enzyme (ACE) inhibitory activity...
  34. Duru M, Ozturk M, Ugur A, Ceylan O. The constituents of essential oil and in vitro antimicrobial activity of Micromeria cilicica from Turkey. J Ethnopharmacol. 2004;94:43-8 pubmed
    ..Pulegone also showed antimicrobial activity, particularly against Candida albicans and Salmonella typhimurium. Furthermore Candida albicans is the most susceptible to pulegone giving two times the effect of nystatin...
  35. Mangathayaru K, Lakshmikant J, Shyam Sundar N, Swapna R, Grace X, Vasantha J. Antimicrobial activity of Leucas aspera flowers. Fitoterapia. 2005;76:752-4 pubmed
  36. Rasikari H, Leach D, Waterman P, Spooner Hart R, Basta A, Banbury L, et al. Acaricidal and cytotoxic activities of extracts from selected genera of Australian Lamiaceae. J Econ Entomol. 2005;98:1259-66 pubmed
    Crude foliar extracts of 67 species from six subfamilies of Australian Lamiaceae were screened by whole organism contact toxicity on the polyphagous mite Tetranychus urticae Koch (Acari: Tetranychidae) by using a Potter precision spray ..
  37. Trusty J, Olmstead R, Santos Guerra A, Sá Fontinha S, Francisco Ortega J. Molecular phylogenetics of the Macaronesian-endemic genus Bystropogon (Lamiaceae): palaeo-islands, ecological shifts and interisland colonizations. Mol Ecol. 2005;14:1177-89 pubmed
    Abstract A molecular phylogenetic study of Bystropogon L'Her. (Lamiaceae) is presented...
  38. Shaiq Ali M, Saleem M, Ahmad W, Parvez M, Yamdagni R. A chlorinated monoterpene ketone, acylated beta-sitosterol glycosides and a flavanone glycoside from Mentha longifolia (Lamiaceae). Phytochemistry. 2002;59:889-95 pubmed
    Mentha longifolia (Lamiaceae), an aromatic herb yielded a new halogenated chloro-derivative of menthone (longifone), two new derivatives of beta-sitosterol glycoside (longiside-A and -B) and a new flavanone-glycoside (longitin)...
  39. Ali M, Saleem M, Ali Z, Ahmad V. Chemistry of Zataria multiflora (Lamiaceae). Phytochemistry. 2000;55:933-6 pubmed
    ..The structures of all the isolated constituents were elucidated by means of spectroscopic methods including 2D-NMR techniques...
  40. Gersbach P. The essential oil secretory structures of Prostanthera ovalifolia (Lamiaceae). Ann Bot. 2002;89:255-60 pubmed
    ..The leaves of P. ovalifolia have glandular trichomes of the peltate type common to many Lamiaceae species...
  41. Erdemoglu N, Turan N, Cakici I, Sener B, Aydin A. Antioxidant activities of some Lamiaceae plant extracts. Phytother Res. 2006;20:9-13 pubmed
    The antioxidant activities of four Lamiaceae plants, Salvia viridis L., Salvia multicaulis Vahl, Stachys byzantina C. Koch and Eremostachys laciniata (L...
  42. Aronne G, De Micco V, Scala M. Effects of relative humidity and temperature conditions on pollen fluorochromatic reaction of Rosmarinus officinalis L. (Lamiaceae). Protoplasma. 2006;228:127-30 pubmed
    ..Therefore "vernalization" of rosemary pollen enhances its viability, supporting that pollen behavior is adapted to winter condition and allows flowering in winter and early spring...
  43. Edwards C, Soltis D, Soltis P. Using patterns of genetic structure based on microsatellite loci to test hypotheses of current hybridization, ancient hybridization and incomplete lineage sorting in Conradina (Lamiaceae). Mol Ecol. 2008;17:5157-74 pubmed publisher
    ..have been suggested to have played major roles based on phylogenetic data is Conradina, a genus of mints (Lamiaceae) endemic to the southeastern USA containing several endangered species...
  44. Sarikurkcu C, Tepe B, Daferera D, Polissiou M, Harmandar M. Studies on the antioxidant activity of the essential oil and methanol extract of Marrubium globosum subsp. globosum (lamiaceae) by three different chemical assays. Bioresour Technol. 2008;99:4239-46 pubmed
    ..60+/-0.74 microg/mg). A positive correlation was observed between the antioxidant activity potential and total phenolic level of the extracts. On the other hand, total flavonoid content was found equal for the both sub-fractions...
  45. Tozin L, Mayo Marques M, Maria Rodrigues T. Herbivory by leaf-cutter ants changes the glandular trichomes density and the volatile components in an aromatic plant model. AoB Plants. 2017;9:plx057 pubmed publisher
    ..are the main sites of production of volatile organic compounds (VOCs) with several chemical properties in Lamiaceae species...
  46. Wu Q, Yu C, Yan Y, Chen J, Zhang C, Wen X. Antiviral flavonoids from Mosla scabra. Fitoterapia. 2010;81:429-33 pubmed publisher
    ..Compared with ribavirin, EFMS appeared to have similar efficacy against influenza viruses, was considered to be less toxic and may warrant further evaluation as a possible agent for the treatment of influenza. ..
  47. Guleryuz G, Erdemir U, Arslan H, Gucer S. Elemental composition of Marrubium astracanicum Jacq. growing in tungsten-contaminated sites. Environ Sci Pollut Res Int. 2016;23:18332-42 pubmed publisher
    ..b>Lamiaceae), around the abandoned tungsten mine on Uluda? Mountain, Turkey, to determine if it is an appropriate candidate ..
  48. Alonso C, Perez R, Bazaga P, Medrano M, Herrera C. Within-plant variation in seed size and inflorescence fecundity is associated with epigenetic mosaicism in the shrub Lavandula latifolia (Lamiaceae). Ann Bot. 2017;: pubmed publisher
    ..The hypothesis that continuous within-plant variation in some phenotypic traits can be associated with epigenetic mosaicism was examined...
  49. Sakamoto R, Ito M, Kawakubo N. Contribution of pollinators to seed production as revealed by differential pollinator exclusion in Clerodendrum trichotomum (Lamiaceae). PLoS ONE. 2012;7:e33803 pubmed publisher
    ..pyrrhosticta probably promotes self- pollination, this species is a non-effective pollinator. This is the first study to separate and compare the contribution of various visitors to the reproductive success of a plant. ..
  50. Suroowan S, Mahomoodally M. A comparative ethnopharmacological analysis of traditional medicine used against respiratory tract diseases in Mauritius. J Ethnopharmacol. 2016;177:61-80 pubmed publisher
    ..The most used plant species belonged to the following taxa; Lamiaceae (9%), Fabaceae (7%) and Rutaceae (7%)...
  51. Zhang F, Yang Q, Zhang S. Dual Effect of Phenolic Nectar on Three Floral Visitors of Elsholtzia rugulosa (Lamiaceae) in SW China. PLoS ONE. 2016;11:e0154381 pubmed publisher
    ..rugulosa Hemsl. (Lamiaceae) in SW China...
  52. Rossi Y, Canavoso L, Palacios S. Molecular response of Musca domestica L. to Mintostachys verticillata essential oil, (4R)+-pulegone and menthone. Fitoterapia. 2012;83:336-42 pubmed publisher
    ..verticillata EO. Consequently, resistant strains overexpressing P450 genes will be more susceptible to either M. verticillata EO or (4R)(+)-pulegone and menthone...
  53. Masoudi S, Rustaiyan A, Mohebat R, Mosslemin M. Composition of the essential oils and antibacterial activities of Hymenocrater yazdianus, Stachys obtusicrena and Nepeta asterotricha three Labiatae herbs growing wild in Iran. Nat Prod Commun. 2012;7:117-20 pubmed
    ..The growth inhibitory zone (mm) was also measured...
  54. Kulkarni R, Shurpali K, Puranik V, Sarkar D, Joshi S. Antimycobacterial labdane diterpenes from Leucas stelligera. J Nat Prod. 2013;76:1836-41 pubmed publisher
    ..Compounds 1-4 exhibited selective antimycobacterial activity against Mycobacterium tuberculosis with IC50 values in the range 5.02-9.80 ?g/mL. ..
  55. Kahaliw W, Hellman B, Engidawork E. Genotoxicity study of Ethiopian medicinal plant extracts on HepG2 cells. BMC Complement Altern Med. 2018;18:45 pubmed publisher
    ..Such evaluation should include other end-points of genotoxicity apart from DNA damage, and possibly also pure compounds. ..
  56. Khan S, Shehzad O, Jin H, Woo E, Kang S, Baek S, et al. Anti-inflammatory mechanism of 15,16-epoxy-3?-hydroxylabda-8,13(16),14-trien-7-one via inhibition of LPS-induced multicellular signaling pathways. J Nat Prod. 2012;75:67-71 pubmed publisher
    ..The LPS-induced mitogen-activated protein kinases (p-JNK, p-p38, and p-ERK) and p-Akt were inhibited after 30 and 10 min of LPS stimulation, respectively. In addition, TNF-? production was suppressed by 1. ..
  57. Maggi F, Mártonfi P, Conti F, Cristalli G, Papa F, Sagratini G, et al. Volatile components of whole and different plant parts of bastard balm (Melittis melissophyllum L., Lamiaceae) collected in Central Italy and Slovakia. Chem Biodivers. 2011;8:2057-79 pubmed publisher
    ..b>Lamiaceae) populations collected in Italy and Slovakia by HS-SPME, and to identify the headspace constituents responsible ..
  58. Dhamija I, Kumar N, Manjula S, Parihar V, Setty M, Pai K. Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of Premna herbacea Roxb. in Ehrlich ascites carcinoma model and Dalton's lymphoma ascites model. Exp Toxicol Pathol. 2013;65:235-42 pubmed publisher
    ..m. injection of 1 million DLA cells. Both the extracts and the fractions possessed potent antitumor activity against solid tumor models by significantly reducing the solid tumor weight and volume. ..
  59. Mathela C, Padalia R, Joshi S, Singh K, Bisht D, Pant A, et al. Chemical diversity in Himalayan Elsholtzia species. Chem Biodivers. 2009;6:2217-26 pubmed publisher
    ..Based on the major constituents of the essential oils, six chemical groups were obtained. ..
  60. Furukawa M, Makino M, Ohkoshi E, Uchiyama T, Fujimoto Y. Terpenoids and phenethyl glucosides from Hyssopus cuspidatus (Labiatae). Phytochemistry. 2011;72:2244-52 pubmed publisher
    ..Their structures were determined by spectroscopic means. The abietane-type diterpenoids (1, 9, 10), rosmarinic acid (15) and salvigenin (17) inhibited leukotriene (LT) C(4) secretion from primary alveolar cells of Wistar rats. ..
  61. Gazim Z, Amorim A, Hovell A, Rezende C, Nascimento I, Ferreira G, et al. Seasonal variation, chemical composition, and analgesic and antimicrobial activities of the essential oil from leaves of Tetradenia riparia (Hochst.) Codd in southern Brazil. Molecules. 2010;15:5509-24 pubmed publisher
    ..aureus, B. subtilis, and Candida albicans were the most sensitive microorganisms, showing largest inhibition, and the lowest MIC values varied from 15.6 to 31.2 microg/mL, 7.8 to 15.6 microg/mL, and 31.2 to 62.5 microg/mL, respectively. ..
  62. Milovanovic M, Zivkovic D, Vucelic Radovic B. Antioxidant effects of Glechoma hederacea as a food additive. Nat Prod Commun. 2010;5:61-3 pubmed
    The antioxidant properties of Glechoma hederacea L. (Lamiaceae), of Serbian origin, were studied in respect to its potential use in foodstuffs...
  63. Huang Z, Jiang D, Lai X. [Study on the enrichment and purification of total flavonoids in Schizonepeta tenuifolia by macroporous adsorption resin]. Zhong Yao Cai. 2010;33:1476-80 pubmed
    ..To establish an optimum enrichment and purification process of total flavonoids in Schizonepeta tenuifolia by macroporous resins...
  64. Xia Y, Qi Y, Yuan Y, Wang G, Cui J, Chen Y, et al. Overexpression of Elsholtzia haichowensis metallothionein 1 (EhMT1) in tobacco plants enhances copper tolerance and accumulation in root cytoplasm and decreases hydrogen peroxide production. J Hazard Mater. 2012;233-234:65-71 pubmed publisher
    ..In addition, our results also indicate that EhMT1-overexpressing tobacco has a more efficient antioxidant system, with improved peroxidase activity to better cope with oxidative stress...
  65. Karaca M, Ince A, Aydin A, Ay S. Cross-genera transferable e-microsatellite markers for 12 genera of the Lamiaceae family. J Sci Food Agric. 2013;93:1869-79 pubmed publisher
    The Lamiaceae family contains many high-valued medicinal, aromatic and ornamental plant species. Several members of the genera in this family are under heavy pressure of collection for commercial use...
  66. Monforte M, Lanuzza F, Pergolizzi S, Mondello F, Tzakou O, Galati E. Protective effect of Calamintha officinalis Moench leaves against alcohol-induced gastric mucosa injury in rats. Macroscopic, histologic and phytochemical analysis. Phytother Res. 2012;26:839-44 pubmed publisher
    Calamintha officinalis Moench (Lamiaceae) is an aromatic plant used since ancient times for its preservative and medicinal properties...
  67. Azizkhani M, Elizaquivel P, Sanchez G, Selma M, Aznar R. Comparative efficacy of Zataria multiflora Boiss., Origanum compactum and Eugenia caryophyllus essential oils against E. coli O157:H7, feline calicivirus and endogenous microbiota in commercial baby-leaf salads. Int J Food Microbiol. 2013;166:249-55 pubmed publisher
    ..However, further research should be done into foodborne viruses in order to improve food safety...
  68. Choudhary A, Sunojkumar P, Mishra G. Fatty acid profiling and multivariate analysis in the genus Leucas reveals its nutritional, pharmaceutical and chemotaxonomic significance. Phytochemistry. 2017;143:72-80 pubmed publisher
    ..Laballenic and phlomic acids are unusual allenic fatty acids found in few Lamiaceae members from order Lamiales...
  69. Park S, Kim S, Suk K, Lee H, Kwon T, Ju M, et al. Clinopodium gracile inhibits mast cell-mediated allergic inflammation: involvement of calcium and nuclear factor-kappaB. Exp Biol Med (Maywood). 2010;235:606-13 pubmed publisher
    ..Our findings provide evidence that WECG inhibits mast cell-derived allergic inflammation and involvement of calcium and NF-kappaB in these effects...
  70. Murugan R, Mallavarapu G. Composition of the essential oil of Pogostemon travancoricus var. travancoricus. Nat Prod Commun. 2012;7:87-8 pubmed
    ..The major components of the oil were bicyclogermacrene (16.0%), cis-calamenene (6.3%), germacrene B (11.1%), spathulenol (7.6%), viridiflorol (5.8%), alpha-cadinol (4.2%) and pogostone (9.9%)...
  71. Selenge E, Murata T, Kobayashi K, Batkhuu J, Yoshizaki F. Flavone tetraglycosides and benzyl alcohol glycosides from the Mongolian medicinal plant Dracocephalum ruyschiana. J Nat Prod. 2013;76:186-93 pubmed publisher
    ..The compounds were tested for antioxidant activity using DPPH. Although the new compounds were not active, phenylpropanoylquinic acid derivatives were revealed as radical scavengers in D. ruyschiana...