medicago truncatula

Summary

Summary: A plant species of the family FABACEAE used to study GENETICS because it is DIPLOID, self fertile, has a small genome, and short generation time.

Top Publications

  1. Pauly N, Ferrari C, Andrio E, Marino D, Piardi S, Brouquisse R, et al. MtNOA1/RIF1 modulates Medicago truncatula-Sinorhizobium meliloti nodule development without affecting its nitric oxide content. J Exp Bot. 2011;62:939-48 pubmed publisher
    ..in the legume-rhizobium symbiosis has been shown, the involvement of an AtNoa1/Rif1 orthologue from Medicago truncatula (MtNoa1/Rif1) during its symbiotic interaction with Sinorhizobium meliloti has been studied...
  2. Kamphuis L, Williams A, Küster H, Trengove R, Singh K, Oliver R, et al. Phoma medicaginis stimulates the induction of the octadecanoid and phenylpropanoid pathways in Medicago truncatula. Mol Plant Pathol. 2012;13:593-603 pubmed publisher
    Gene expression changes and metabolite abundances were measured during the interaction of Medicago truncatula with the fungal necrotrophic pathogen Phoma medicaginis in leaf tissue of susceptible and resistant accessions...
  3. Cam Y, Pierre O, Boncompagni E, Herouart D, Meilhoc E, Bruand C. Nitric oxide (NO): a key player in the senescence of Medicago truncatula root nodules. New Phytol. 2012;196:548-60 pubmed publisher
    ..NO is required for an optimal establishment of the Medicago truncatula-Sinorhizobium meliloti symbiotic interaction, but little is known about the role of NO in mature nodules...
  4. Zhao Q, Tobimatsu Y, Zhou R, Pattathil S, Gallego Giraldo L, Fu C, et al. Loss of function of cinnamyl alcohol dehydrogenase 1 leads to unconventional lignin and a temperature-sensitive growth defect in Medicago truncatula. Proc Natl Acad Sci U S A. 2013;110:13660-5 pubmed publisher
    ..We have identified Tnt1 retrotransposon insertion mutants of barrel medic (Medicago truncatula) that show reduced lignin autofluorescence under UV microscopy and red coloration in interfascicular fibers...
  5. El Msehli S, Lambert A, Baldacci Cresp F, Hopkins J, Boncompagni E, Smiti S, et al. Crucial role of (homo)glutathione in nitrogen fixation in Medicago truncatula nodules. New Phytol. 2011;192:496-506 pubmed publisher
    ..Taken together, these data show that the plant (h)GSH content of the nodule nitrogen-fixing zone modulates the efficiency of the BNF process, demonstrating their important role in the regulation of this process. ..
  6. Liu W, Kohlen W, Lillo A, Op den Camp R, Ivanov S, Hartog M, et al. Strigolactone biosynthesis in Medicago truncatula and rice requires the symbiotic GRAS-type transcription factors NSP1 and NSP2. Plant Cell. 2011;23:3853-65 pubmed publisher
    ..Here, we show that NSP1 and NSP2 are indispensable for strigolactone (SL) biosynthesis in the legume Medicago truncatula and in rice. Mutant nsp1 plants do not produce SLs, whereas in M...
  7. Limpens E, Moling S, Hooiveld G, Pereira P, Bisseling T, Becker J, et al. cell- and tissue-specific transcriptome analyses of Medicago truncatula root nodules. PLoS ONE. 2013;8:e64377 pubmed publisher
    ..specific cells/tissues at different stages of symbiosome formation from nodules of the model legume Medicago truncatula using laser-capture microdissection...
  8. Dias P, Brunel Muguet S, Dürr C, Huguet T, Demilly D, Wagner M, et al. QTL analysis of seed germination and pre-emergence growth at extreme temperatures in Medicago truncatula. Theor Appl Genet. 2011;122:429-44 pubmed publisher
    ..analysis was carried out at sub- and supra-optimal temperatures at these early stages in the model Legume Medicago truncatula. On the basis of an ecophysiological model framework, two populations of recombinant inbred lines were ..
  9. Uppalapati S, Ishiga Y, Doraiswamy V, Bedair M, Mittal S, Chen J, et al. Loss of abaxial leaf epicuticular wax in Medicago truncatula irg1/palm1 mutants results in reduced spore differentiation of anthracnose and nonhost rust pathogens. Plant Cell. 2012;24:353-70 pubmed publisher
    ..genes that confer nonhost resistance to biotrophic fungal pathogens, we did a forward-genetics screen using Medicago truncatula Tnt1 retrotransposon insertion lines...
  10. Mortier V, Den Herder G, Whitford R, Van de Velde W, Rombauts S, D haeseleer K, et al. CLE peptides control Medicago truncatula nodulation locally and systemically. Plant Physiol. 2010;153:222-37 pubmed publisher
    ..role of CLE peptides during indeterminate nodule development and identified 25 MtCLE peptide genes in the Medicago truncatula genome, of which two genes, MtCLE12 and MtCLE13, had nodulation-related expression patterns that were ..

Detail Information

Publications104 found, 100 shown here

  1. Pauly N, Ferrari C, Andrio E, Marino D, Piardi S, Brouquisse R, et al. MtNOA1/RIF1 modulates Medicago truncatula-Sinorhizobium meliloti nodule development without affecting its nitric oxide content. J Exp Bot. 2011;62:939-48 pubmed publisher
    ..in the legume-rhizobium symbiosis has been shown, the involvement of an AtNoa1/Rif1 orthologue from Medicago truncatula (MtNoa1/Rif1) during its symbiotic interaction with Sinorhizobium meliloti has been studied...
  2. Kamphuis L, Williams A, Küster H, Trengove R, Singh K, Oliver R, et al. Phoma medicaginis stimulates the induction of the octadecanoid and phenylpropanoid pathways in Medicago truncatula. Mol Plant Pathol. 2012;13:593-603 pubmed publisher
    Gene expression changes and metabolite abundances were measured during the interaction of Medicago truncatula with the fungal necrotrophic pathogen Phoma medicaginis in leaf tissue of susceptible and resistant accessions...
  3. Cam Y, Pierre O, Boncompagni E, Herouart D, Meilhoc E, Bruand C. Nitric oxide (NO): a key player in the senescence of Medicago truncatula root nodules. New Phytol. 2012;196:548-60 pubmed publisher
    ..NO is required for an optimal establishment of the Medicago truncatula-Sinorhizobium meliloti symbiotic interaction, but little is known about the role of NO in mature nodules...
  4. Zhao Q, Tobimatsu Y, Zhou R, Pattathil S, Gallego Giraldo L, Fu C, et al. Loss of function of cinnamyl alcohol dehydrogenase 1 leads to unconventional lignin and a temperature-sensitive growth defect in Medicago truncatula. Proc Natl Acad Sci U S A. 2013;110:13660-5 pubmed publisher
    ..We have identified Tnt1 retrotransposon insertion mutants of barrel medic (Medicago truncatula) that show reduced lignin autofluorescence under UV microscopy and red coloration in interfascicular fibers...
  5. El Msehli S, Lambert A, Baldacci Cresp F, Hopkins J, Boncompagni E, Smiti S, et al. Crucial role of (homo)glutathione in nitrogen fixation in Medicago truncatula nodules. New Phytol. 2011;192:496-506 pubmed publisher
    ..Taken together, these data show that the plant (h)GSH content of the nodule nitrogen-fixing zone modulates the efficiency of the BNF process, demonstrating their important role in the regulation of this process. ..
  6. Liu W, Kohlen W, Lillo A, Op den Camp R, Ivanov S, Hartog M, et al. Strigolactone biosynthesis in Medicago truncatula and rice requires the symbiotic GRAS-type transcription factors NSP1 and NSP2. Plant Cell. 2011;23:3853-65 pubmed publisher
    ..Here, we show that NSP1 and NSP2 are indispensable for strigolactone (SL) biosynthesis in the legume Medicago truncatula and in rice. Mutant nsp1 plants do not produce SLs, whereas in M...
  7. Limpens E, Moling S, Hooiveld G, Pereira P, Bisseling T, Becker J, et al. cell- and tissue-specific transcriptome analyses of Medicago truncatula root nodules. PLoS ONE. 2013;8:e64377 pubmed publisher
    ..specific cells/tissues at different stages of symbiosome formation from nodules of the model legume Medicago truncatula using laser-capture microdissection...
  8. Dias P, Brunel Muguet S, Dürr C, Huguet T, Demilly D, Wagner M, et al. QTL analysis of seed germination and pre-emergence growth at extreme temperatures in Medicago truncatula. Theor Appl Genet. 2011;122:429-44 pubmed publisher
    ..analysis was carried out at sub- and supra-optimal temperatures at these early stages in the model Legume Medicago truncatula. On the basis of an ecophysiological model framework, two populations of recombinant inbred lines were ..
  9. Uppalapati S, Ishiga Y, Doraiswamy V, Bedair M, Mittal S, Chen J, et al. Loss of abaxial leaf epicuticular wax in Medicago truncatula irg1/palm1 mutants results in reduced spore differentiation of anthracnose and nonhost rust pathogens. Plant Cell. 2012;24:353-70 pubmed publisher
    ..genes that confer nonhost resistance to biotrophic fungal pathogens, we did a forward-genetics screen using Medicago truncatula Tnt1 retrotransposon insertion lines...
  10. Mortier V, Den Herder G, Whitford R, Van de Velde W, Rombauts S, D haeseleer K, et al. CLE peptides control Medicago truncatula nodulation locally and systemically. Plant Physiol. 2010;153:222-37 pubmed publisher
    ..role of CLE peptides during indeterminate nodule development and identified 25 MtCLE peptide genes in the Medicago truncatula genome, of which two genes, MtCLE12 and MtCLE13, had nodulation-related expression patterns that were ..
  11. Li D, Zhang Y, Hu X, Shen X, Ma L, Su Z, et al. Transcriptional profiling of Medicago truncatula under salt stress identified a novel CBF transcription factor MtCBF4 that plays an important role in abiotic stress responses. BMC Plant Biol. 2011;11:109 pubmed publisher
    ..We conducted a detailed pathway analysis of transcriptional dynamics in the roots of Medicago truncatula seedlings under salt stress and selected a transcription factor gene, MtCBF4, for experimental validation. ..
  12. Capoen W, Sun J, Wysham D, Otegui M, Venkateshwaran M, Hirsch S, et al. Nuclear membranes control symbiotic calcium signaling of legumes. Proc Natl Acad Sci U S A. 2011;108:14348-53 pubmed publisher
  13. Casieri L, Gallardo K, Wipf D. Transcriptional response of Medicago truncatula sulphate transporters to arbuscular mycorrhizal symbiosis with and without sulphur stress. Planta. 2012;235:1431-47 pubmed publisher
    ..MtSULTRs) were performed to better understand the beneficial effects of mycorrhizal interaction on Medicago truncatula plants colonized by Glomus intraradices at different sulphate concentrations...
  14. Jones K. Increased production of the exopolysaccharide succinoglycan enhances Sinorhizobium meliloti 1021 symbiosis with the host plant Medicago truncatula. J Bacteriol. 2012;194:4322-31 pubmed publisher
    ..meliloti 1021 with the host plant Medicago truncatula cv. Jemalong A17...
  15. Morandi D, Le Signor C, Gianinazzi Pearson V, Duc G. A Medicago truncatula mutant hyper-responsive to mycorrhiza and defective for nodulation. Mycorrhiza. 2009;19:435-441 pubmed publisher
    ..In this paper, we report a new Medicago truncatula mutant defective for nodulation but hypermycorrhizal for symbiosis development and response...
  16. Ariel F, Brault Hernandez M, Laffont C, Huault E, Brault M, Plet J, et al. Two direct targets of cytokinin signaling regulate symbiotic nodulation in Medicago truncatula. Plant Cell. 2012;24:3838-52 pubmed publisher
    ..sequence bound in vitro by a transcription factor (TF) acting in cytokinin signaling, the nodule-enhanced Medicago truncatula Mt RR1 response regulator (RR)...
  17. Bogacki P, Peck D, Nair R, Howie J, Oldach K. Genetic analysis of tolerance to boron toxicity in the legume Medicago truncatula. BMC Plant Biol. 2013;13:54 pubmed publisher
    b>Medicago truncatula Gaertn. (barrel medic) is cultivated as a pasture legume for its high protein content and ability to improve soils through nitrogen fixation...
  18. Le Signor C, Savois V, Aubert G, Verdier J, Nicolas M, Pagny G, et al. Optimizing TILLING populations for reverse genetics in Medicago truncatula. Plant Biotechnol J. 2009;7:430-41 pubmed publisher
    b>Medicago truncatula has been widely adopted as a model plant for crop legume species of the Vicieae...
  19. Sulieman S, Schulze J. The efficiency of nitrogen fixation of the model legume Medicago truncatula (Jemalong A17) is low compared to Medicago sativa. J Plant Physiol. 2010;167:683-92 pubmed publisher
    b>Medicago truncatula (Gaertn.) (barrel medic) serves as a model legume in plant biology. Numerous studies have addressed molecular aspects of the biology of M...
  20. Verdier J, Zhao J, Torres Jerez I, Ge S, Liu C, He X, et al. MtPAR MYB transcription factor acts as an on switch for proanthocyanidin biosynthesis in Medicago truncatula. Proc Natl Acad Sci U S A. 2012;109:1766-71 pubmed publisher
    MtPAR (Medicago truncatula proanthocyanidin regulator) is an MYB family transcription factor that functions as a key regulator of proanthocyanidin (PA) biosynthesis in the model legume Medicago truncatula...
  21. Czaja L, Hogekamp C, Lamm P, Maillet F, Martinez E, Samain E, et al. Transcriptional responses toward diffusible signals from symbiotic microbes reveal MtNFP- and MtDMI3-dependent reprogramming of host gene expression by arbuscular mycorrhizal fungal lipochitooligosaccharides. Plant Physiol. 2012;159:1671-85 pubmed publisher
    ..Irrespective of different outcomes, the perception of symbiotic LCOs in Medicago truncatula is mediated by the LysM receptor kinase M. truncatula Nod factor perception (MtNFP)...
  22. Svistoonoff S, Sy M, Diagne N, Barker D, Bogusz D, Franche C. Infection-specific activation of the Medicago truncatula Enod11 early nodulin gene promoter during actinorhizal root nodulation. Mol Plant Microbe Interact. 2010;23:740-7 pubmed publisher
    The MtEnod11 gene from Medicago truncatula is widely used as an early infection-related molecular marker for endosymbiotic associations involving both rhizobia and arbuscular mycorrhizal fungi...
  23. De Mita S, Chantret N, Loridon K, Ronfort J, Bataillon T. Molecular adaptation in flowering and symbiotic recognition pathways: insights from patterns of polymorphism in the legume Medicago truncatula. BMC Evol Biol. 2011;11:229 pubmed publisher
    We studied patterns of molecular adaptation in the wild Mediterranean legume Medicago truncatula. We focused on two phenotypic traits that are not functionally linked: flowering time and perception of symbiotic microbes...
  24. Zhou Z, Zeng H, Liu Z, Yang Z. Genome-wide identification of Medicago truncatula microRNAs and their targets reveals their differential regulation by heavy metal. Plant Cell Environ. 2012;35:86-99 pubmed publisher
    ..CA, USA) to investigate global expression and complexity of microRNAs (miRNAs) and their targets from Medicago truncatula. Two small RNA libraries and two degradome libraries were constructed from mercury (Hg)-treated and Hg-free ..
  25. Gyuricza V, Thiry Y, Wannijn J, Declerck S, Dupré de Boulois H. Radiocesium transfer between Medicago truncatula plants via a common mycorrhizal network. Environ Microbiol. 2010;12:2180-9 pubmed publisher
    ..In the present study, Medicago truncatula plants were connected by a common mycorrhizal network and Prussian Blue (ammonium-ferric-hexacyano ferrate) ..
  26. Schenkluhn L, Hohnjec N, Niehaus K, Schmitz U, Colditz F. Differential gel electrophoresis (DIGE) to quantitatively monitor early symbiosis- and pathogenesis-induced changes of the Medicago truncatula root proteome. J Proteomics. 2010;73:753-68 pubmed publisher
    Symbiosis- and pathogenesis-related early protein induction patterns in the model legume Medicago truncatula were analysed with two-dimensional differential gel electrophoresis...
  27. Li D, Su Z, Dong J, Wang T. An expression database for roots of the model legume Medicago truncatula under salt stress. BMC Genomics. 2009;10:517 pubmed publisher
    b>Medicago truncatula is a model legume whose genome is currently being sequenced by an international consortium. Abiotic stresses such as salt stress limit plant growth and crop productivity, including those of legumes...
  28. Renard M, Alkhalfioui F, Schmitt Keichinger C, Ritzenthaler C, Montrichard F. Identification and characterization of thioredoxin h isoforms differentially expressed in germinating seeds of the model legume Medicago truncatula. Plant Physiol. 2011;155:1113-26 pubmed publisher
    ..To fill this gap, in this work, we characterized the Trx h family of Medicago truncatula, a model legume, and then explored the activity and localization of Trx h isoforms accumulating in seeds...
  29. Nolan K, Kurdyukov S, Rose R. Characterisation of the legume SERK-NIK gene superfamily including splice variants: implications for development and defence. BMC Plant Biol. 2011;11:44 pubmed publisher
    ..The SERK1 gene of the model legume, Medicago truncatula functions in somatic and zygotic embryogenesis, and during many phases of plant development, including ..
  30. Carelli M, Biazzi E, Panara F, Tava A, Scaramelli L, Porceddu A, et al. Medicago truncatula CYP716A12 is a multifunctional oxidase involved in the biosynthesis of hemolytic saponins. Plant Cell. 2011;23:3070-81 pubmed publisher
    ..We have identified a cytochrome P450 gene (CYP716A12) involved in saponin synthesis in Medicago truncatula using a combined genetic and biochemical approach...
  31. Melo P, Silva L, Ribeiro I, Seabra A, Carvalho H. Glutamine synthetase is a molecular target of nitric oxide in root nodules of Medicago truncatula and is regulated by tyrosine nitration. Plant Physiol. 2011;157:1505-17 pubmed publisher
    ..synthetase (GS), a key enzyme for root nodule metabolism, is a molecular target of NO in root nodules of Medicago truncatula, being regulated by tyrosine (Tyr) nitration in relation to active nitrogen fixation...
  32. Guan D, Stacey N, Liu C, Wen J, Mysore K, Torres Jerez I, et al. Rhizobial infection is associated with the development of peripheral vasculature in nodules of Medicago truncatula. Plant Physiol. 2013;162:107-15 pubmed publisher
    ..Using a new allele of the Medicago truncatula mutant Lumpy Infections, lin-4, which forms normal infection pockets but cannot initiate infection threads, ..
  33. Castillejo M, Maldonado A, Dumas Gaudot E, Fernández Aparicio M, Susín R, Diego R, et al. Differential expression proteomics to investigate responses and resistance to Orobanche crenata in Medicago truncatula. BMC Genomics. 2009;10:294 pubmed publisher
    ..The level of protection achieved to date is either incomplete or ephemeral. Hence, an efficient control of the parasite requires a better understanding of its interaction and associated resistance mechanisms at molecular levels...
  34. Zhang L, Zhao M, Tian Q, Zhang W. Comparative studies on tolerance of Medicago truncatula and Medicago falcata to freezing. Planta. 2011;234:445-57 pubmed publisher
    ..falcata in response to cold acclimation and freezing with those of the legume model plant Medicago truncatula. M. falcata seedlings were more tolerant to freezing than M...
  35. Zahaf O, Blanchet S, de Z licourt A, Alunni B, Plet J, Laffont C, et al. Comparative transcriptomic analysis of salt adaptation in roots of contrasting Medicago truncatula genotypes. Mol Plant. 2012;5:1068-81 pubmed publisher
    ..We analyzed in the Medicago truncatula legume the root transcriptome of two genotypes having contrasting responses to salt stress: TN1...
  36. Viollet A, Corberand T, Mougel C, Robin A, Lemanceau P, Mazurier S. Fluorescent pseudomonads harboring type III secretion genes are enriched in the mycorrhizosphere of Medicago truncatula. FEMS Microbiol Ecol. 2011;75:457-67 pubmed publisher
    ..mycorrhizal fungi (AMF) on the enrichment of T3SS+ fluorescent pseudomonads in the rhizosphere of Medicago truncatula, their frequency was assessed among pseudomonads isolated from mycorrhizal and nonmycorrhizal roots and ..
  37. Klaus Heisen D, Nurisso A, Pietraszewska Bogiel A, Mbengue M, Camut S, Timmers T, et al. Structure-function similarities between a plant receptor-like kinase and the human interleukin-1 receptor-associated kinase-4. J Biol Chem. 2011;286:11202-10 pubmed publisher
    ..The lysin motif domain-containing receptor-like kinase-3 (LYK3) of the legume Medicago truncatula shows 33% amino acid sequence identity with human IRAK-4 over the kinase domain...
  38. Van de Velde W, Zehirov G, Szatmari A, Debreczeny M, Ishihara H, Kevei Z, et al. Plant peptides govern terminal differentiation of bacteria in symbiosis. Science. 2010;327:1122-6 pubmed publisher
    Legume plants host nitrogen-fixing endosymbiotic Rhizobium bacteria in root nodules. In Medicago truncatula, the bacteria undergo an irreversible (terminal) differentiation mediated by hitherto unidentified plant factors...
  39. Naoumkina M, Modolo L, Huhman D, Urbanczyk Wochniak E, Tang Y, Sumner L, et al. Genomic and coexpression analyses predict multiple genes involved in triterpene saponin biosynthesis in Medicago truncatula. Plant Cell. 2010;22:850-66 pubmed publisher
    ..in the elaboration, hydroxylation, and glycosylation of the triterpene skeleton in the model legume Medicago truncatula. Four candidate uridine diphosphate glycosyltransferases were expressed in Escherichia coli, one of which (..
  40. Chabaud M, Genre A, Sieberer B, Faccio A, Fournier J, Novero M, et al. Arbuscular mycorrhizal hyphopodia and germinated spore exudates trigger Ca2+ spiking in the legume and nonlegume root epidermis. New Phytol. 2011;189:347-55 pubmed publisher
    ..Root organ cultures of both Medicago truncatula and Daucus carota, expressing the nuclear-localized cameleon reporter NupYC2...
  41. Tesfaye M, Silverstein K, Nallu S, Wang L, Botanga C, Gomez S, et al. Spatio-temporal expression patterns of Arabidopsis thaliana and Medicago truncatula defensin-like genes. PLoS ONE. 2013;8:e58992 pubmed publisher
    ..a custom Affymetrix chip consisting of probe sets for 317 and 684 DEFLs from Arabidopsis thaliana and Medicago truncatula, respectively for cataloging DEFL expression in a variety of plant organs at different developmental stages ..
  42. Coba de la Peña T, Redondo F, Manrique E, Lucas M, Pueyo J. Nitrogen fixation persists under conditions of salt stress in transgenic Medicago truncatula plants expressing a cyanobacterial flavodoxin. Plant Biotechnol J. 2010;8:954-65 pubmed publisher
    ..legume nitrogen fixation under saline conditions, the flavodoxin gene was introduced into the model legume Medicago truncatula. Expression of flavodoxin did not confer saline tolerance to the whole plant, although the sensitive ..
  43. Liu W, Chen A, Luo L, Sun J, Cao L, Yu G, et al. Characterization and expression analysis of Medicago truncatula ROP GTPase family during the early stage of symbiosis. J Integr Plant Biol. 2010;52:639-52 pubmed publisher
    ..In this study, seven cDNA clones coding for ROP GTPases have been isolated in Medicago truncatula, and conserved and divergent domains are identified in these predicted MtROP proteins...
  44. Pumplin N, Zhang X, Noar R, Harrison M. Polar localization of a symbiosis-specific phosphate transporter is mediated by a transient reorientation of secretion. Proc Natl Acad Sci U S A. 2012;109:E665-72 pubmed publisher
    ..periarbuscular membrane, that contains a unique set of proteins including phosphate transporters such as Medicago truncatula MtPT4 [Javot et al...
  45. Bozsó Z, Maunoury N, Szatmari A, Mergaert P, Ott P, Zsíros L, et al. Transcriptome analysis of a bacterially induced basal and hypersensitive response of Medicago truncatula. Plant Mol Biol. 2009;70:627-46 pubmed publisher
    Research using the well-studied model legume Medicago truncatula has largely focused on rhizobium symbiosis, while little information is currently available for this species on pathogen-induced transcriptome changes...
  46. He J, Benedito V, Wang M, Murray J, Zhao P, Tang Y, et al. The Medicago truncatula gene expression atlas web server. BMC Bioinformatics. 2009;10:441 pubmed publisher
    ..Transcriptomics studies in the model legume species, Medicago truncatula, are instrumental in helping to formulate hypotheses about the role of legume genes...
  47. Chen H, Li F, Yuan H, Xiao X, Yang G, Wu L. Abscopal signals mediated bio-effects in low-energy ion irradiated Medicago truncatula seeds. J Radiat Res. 2010;51:651-6 pubmed
    ..In this study, the bio-effects and the preliminary mechanisms of low energy ion beam irradiation on Medicago truncatula were investigated...
  48. Rodríguez Celma J, Lattanzio G, Grusak M, Abadía A, Abadía J, López Millán A. Root responses of Medicago truncatula plants grown in two different iron deficiency conditions: changes in root protein profile and riboflavin biosynthesis. J Proteome Res. 2011;10:2590-601 pubmed publisher
    ..synthesis pathway, including qPCR and riboflavin determination, to investigate Fe-deficiency responses in Medicago truncatula plants grown with and without CaCO(3)...
  49. Fliegmann J, Uhlenbroich S, Shinya T, Martinez Y, Lefebvre B, Shibuya N, et al. Biochemical and phylogenetic analysis of CEBiP-like LysM domain-containing extracellular proteins in higher plants. Plant Physiol Biochem. 2011;49:709-20 pubmed publisher
    ..We analyzed a representative of each type, MtLYM1 and MtLYM2, from Medicago truncatula at the biochemical level and with respect to their expression patterns and observed some similarities but ..
  50. de Z licourt A, Diet A, Marion J, Laffont C, Ariel F, Moison M, et al. Dual involvement of a Medicago truncatula NAC transcription factor in root abiotic stress response and symbiotic nodule senescence. Plant J. 2012;70:220-30 pubmed publisher
    Legume crops related to the model plant Medicago truncatula can adapt their root architecture to environmental conditions, both by branching and by establishing a symbiosis with rhizobial bacteria to form nitrogen-fixing nodules...
  51. Xi J, Chen Y, Nakashima J, Wang S, Chen R. Medicago truncatula esn1 defines a genetic locus involved in nodule senescence and symbiotic nitrogen fixation. Mol Plant Microbe Interact. 2013;26:893-902 pubmed publisher
    Symbiotic interaction between Medicago truncatula and Sinorhizobium meliloti results in the formation on the host roots of new organs, nodules, in which biological nitrogen fixation takes place...
  52. Seabra A, Silva L, Carvalho H. Novel aspects of glutamine synthetase (GS) regulation revealed by a detailed expression analysis of the entire GS gene family of Medicago truncatula under different physiological conditions. BMC Plant Biol. 2013;13:137 pubmed publisher
    ..b>Medicago truncatula provides an excellent model system to study GS, as it contain a very simple GS gene family comprising only ..
  53. Limpens E, Ivanov S, van Esse W, Voets G, Fedorova E, Bisseling T. Medicago N2-fixing symbiosomes acquire the endocytic identity marker Rab7 but delay the acquisition of vacuolar identity. Plant Cell. 2009;21:2811-28 pubmed publisher
    ..We show that in Medicago truncatula, the small GTPases Rab5 and Rab7 are endosomal membrane identity markers, marking different (partly ..
  54. Rogers C, Wen J, Chen R, Oldroyd G. Deletion-based reverse genetics in Medicago truncatula. Plant Physiol. 2009;151:1077-86 pubmed publisher
    ..A population of 156,000 Medicago truncatula plants has been structured as 13 towers each representing 12,000 M2 plants...
  55. Zhao Q, Gallego Giraldo L, Wang H, Zeng Y, Ding S, Chen F, et al. An NAC transcription factor orchestrates multiple features of cell wall development in Medicago truncatula. Plant J. 2010;63:100-14 pubmed publisher
    To identify genes controlling secondary cell wall biosynthesis in the model legume Medicago truncatula, we screened a Tnt1 retrotransposon insertion mutant population for plants with altered patterns of lignin autofluorescence...
  56. Seabra A, Vieira C, Cullimore J, Carvalho H. Medicago truncatula contains a second gene encoding a plastid located glutamine synthetase exclusively expressed in developing seeds. BMC Plant Biol. 2010;10:183 pubmed publisher
    ..This study reports the existence of a second nuclear gene encoding a plastid located GS in Medicago truncatula. ..
  57. Branca A, Paape T, Zhou P, Briskine R, Farmer A, Mudge J, et al. Whole-genome nucleotide diversity, recombination, and linkage disequilibrium in the model legume Medicago truncatula. Proc Natl Acad Sci U S A. 2011;108:E864-70 pubmed publisher
    b>Medicago truncatula is a model for investigating legume genetics, including the genetics and evolution of legume-rhizobia symbiosis...
  58. Osipova M, Mortier V, Demchenko K, Tsyganov V, Tikhonovich I, Lutova L, et al. Wuschel-related homeobox5 gene expression and interaction of CLE peptides with components of the systemic control add two pieces to the puzzle of autoregulation of nodulation. Plant Physiol. 2012;158:1329-41 pubmed publisher
    ..quot; Here, we focus on the role of the WOX5 transcription factor upon nodulation in Medicago truncatula and pea (Pisum sativum) that form indeterminate nodules...
  59. Rodríguez Celma J, Lin W, Fu G, Abadía J, López Millán A, Schmidt W. Mutually exclusive alterations in secondary metabolism are critical for the uptake of insoluble iron compounds by Arabidopsis and Medicago truncatula. Plant Physiol. 2013;162:1473-85 pubmed publisher
    ..changes in the transcriptome of two model species, Arabidopsis (Arabidopsis thaliana) and Medicago truncatula. Transcriptional profiling by RNA sequencing revealed a massive up-regulation of genes coding for enzymes ..
  60. Cannon S, May G, Jackson S. Three sequenced legume genomes and many crop species: rich opportunities for translational genomics. Plant Physiol. 2009;151:970-7 pubmed publisher
  61. Schnabel E, Mukherjee A, Smith L, Kassaw T, Long S, Frugoli J. The lss supernodulation mutant of Medicago truncatula reduces expression of the SUNN gene. Plant Physiol. 2010;154:1390-402 pubmed publisher
    ..We report the identification of a mutant in nodule regulation in Medicago truncatula, like sunn supernodulator (lss), which displays shoot-controlled supernodulation and short roots, similar ..
  62. Horchani F, Pr vot M, Boscari A, Evangelisti E, Meilhoc E, Bruand C, et al. Both plant and bacterial nitrate reductases contribute to nitric oxide production in Medicago truncatula nitrogen-fixing nodules. Plant Physiol. 2011;155:1023-36 pubmed publisher
    ..In the model legume Medicago truncatula, NO production has been detected in the nitrogen fixation zone of the nodule, but the systems responsible ..
  63. Marino D, Andrio E, Danchin E, Oger E, Gucciardo S, Lambert A, et al. A Medicago truncatula NADPH oxidase is involved in symbiotic nodule functioning. New Phytol. 2011;189:580-92 pubmed publisher
    ..Using sequence similarity searches, we identified seven putative RBOH-encoding genes in the Medicago truncatula genome. A phylogenetic reconstruction showed that Rboh gene duplications occurred in legume species...
  64. Murray J, Muni R, Torres Jerez I, Tang Y, Allen S, Andriankaja M, et al. Vapyrin, a gene essential for intracellular progression of arbuscular mycorrhizal symbiosis, is also essential for infection by rhizobia in the nodule symbiosis of Medicago truncatula. Plant J. 2011;65:244-52 pubmed publisher
    ..Recently, it has been discovered that in Medicago truncatula, the Vapyrin (VPY) gene is essential for the establishment of the arbuscular mycorrhizal symbiosis...
  65. Samac D, Penuela S, Schnurr J, Hunt E, Foster Hartnett D, VandenBosch K, et al. Expression of coordinately regulated defence response genes and analysis of their role in disease resistance in Medicago truncatula. Mol Plant Pathol. 2011;12:786-98 pubmed publisher
    ..technology was used to identify the genes associated with disease defence responses in the model legume Medicago truncatula. Transcript profiles from M. truncatula cv...
  66. Zhou C, Han L, Pislariu C, Nakashima J, Fu C, Jiang Q, et al. From model to crop: functional analysis of a STAY-GREEN gene in the model legume Medicago truncatula and effective use of the gene for alfalfa improvement. Plant Physiol. 2011;157:1483-96 pubmed publisher
    b>Medicago truncatula has been developed into a model legume. Its close relative alfalfa (Medicago sativa) is the most widely grown forage legume crop in the United States. By screening a large population of M...
  67. Guo S, Kamphuis L, Gao L, Klingler J, Lichtenzveig J, Edwards O, et al. Identification of distinct quantitative trait loci associated with defence against the closely related aphids Acyrthosiphon pisum and A. kondoi in Medicago truncatula. J Exp Bot. 2012;63:3913-22 pubmed publisher
    Aphids are a major family of plant insect pests. Medicago truncatula and Acyrthosiphon pisum (pea aphid, PA) are model species with a suite of resources available to help dissect the mechanism underlying plant-aphid interactions...
  68. Sankaran R, Huguet T, Grusak M. Identification of QTL affecting seed mineral concentrations and content in the model legume Medicago truncatula. Theor Appl Genet. 2009;119:241-53 pubmed publisher
    ..The main objectives of this study were to use a Medicago truncatula recombinant inbred population (Jemalong-6 x DZA 315...
  69. Jasiński M, Kachlicki P, Rodziewicz P, Figlerowicz M, Stobiecki M. Changes in the profile of flavonoid accumulation in Medicago truncatula leaves during infection with fungal pathogen Phoma medicaginis. Plant Physiol Biochem. 2009;47:847-53 pubmed publisher
    b>Medicago truncatula is a model species for the study of the unique secondary metabolism in legumes. LC/MS/MS analysis was used to identify and profile flavonoid glycoconjugates and free aglycones in leaves of M...
  70. Cheng X, Wen J, Tadege M, Ratet P, Mysore K. Reverse genetics in medicago truncatula using Tnt1 insertion mutants. Methods Mol Biol. 2011;678:179-90 pubmed publisher
    b>Medicago truncatula has been chosen as one of the two model species for legume molecular genetics and functional genomics studies. With the imminent completion of M...
  71. Devers E, Branscheid A, May P, Krajinski F. Stars and symbiosis: microRNA- and microRNA*-mediated transcript cleavage involved in arbuscular mycorrhizal symbiosis. Plant Physiol. 2011;156:1990-2010 pubmed publisher
    ..AM symbiosis, we carried out high-throughput (Illumina) sequencing of small RNAs and degradome tags of Medicago truncatula roots. This led to the annotation of 243 novel miRNAs...
  72. Horvath B, Yeun L, Domonkos A, Halasz G, Gobbato E, Ayaydin F, et al. Medicago truncatula IPD3 is a member of the common symbiotic signaling pathway required for rhizobial and mycorrhizal symbioses. Mol Plant Microbe Interact. 2011;24:1345-58 pubmed publisher
    ..genes required for intracellular accommodation of nitrogen-fixing bacteria and AM fungi, we characterized Medicago truncatula symbiotic mutants defective for rhizobial infection of nodule cells and colonization of root cells by AM ..
  73. Sieberer B, Chabaud M, Fournier J, Timmers A, Barker D. A switch in Ca2+ spiking signature is concomitant with endosymbiotic microbe entry into cortical root cells of Medicago truncatula. Plant J. 2012;69:822-30 pubmed publisher
    ..Live-tissue imaging using calcium cameleon reporters expressed in Medicago truncatula roots has revealed that distinct Ca(2+) oscillatory profiles correlate with specific stages of ..
  74. Rey T, Nars A, Bonhomme M, Bottin A, Huguet S, Balzergue S, et al. NFP, a LysM protein controlling Nod factor perception, also intervenes in Medicago truncatula resistance to pathogens. New Phytol. 2013;198:875-86 pubmed publisher
    ..To study this question, nfp and lyk3 LysM-receptor like kinase mutants of Medicago truncatula that are affected in the early steps of nodulation, were analysed following inoculation with Aphanomyces ..
  75. Gubry Rangin C, Garcia M, Bena G. Partner choice in Medicago truncatula-Sinorhizobium symbiosis. Proc Biol Sci. 2010;277:1947-51 pubmed publisher
    ..strains. In this study, we focused on the widely studied symbiotic association Medicago truncatula-Sinorhizobium meliloti, which forms indeterminate nodules...
  76. Yousfi N, Slama I, Ghnaya T, Savoure A, Abdelly C. Effects of water deficit stress on growth, water relations and osmolyte accumulation in Medicago truncatula and M. laciniata populations. C R Biol. 2010;333:205-13 pubmed publisher
    The effects of water stress were investigated in two Tunisian Medicago truncatula populations collected from arid (Mt-173) and sub-humid (Mt-664) climates and two Tunisian M...
  77. Chen L, Wang T, Zhao M, Zhang W. Ethylene-responsive miRNAs in roots of Medicago truncatula identified by high-throughput sequencing at whole genome level. Plant Sci. 2012;184:14-9 pubmed publisher
    ..b>Medicago truncatula is a model plant widely used for investigation of molecular biology in legume species...
  78. Miao Z, Li D, Zhang Z, Dong J, Su Z, Wang T. Medicago truncatula transporter database: a comprehensive database resource for M. truncatula transporters. BMC Genomics. 2012;13:60 pubmed publisher
    b>Medicago truncatula has been chosen as a model species for genomic studies. It is closely related to an important legume, alfalfa. Transporters are a large group of membrane-spanning proteins...
  79. Gil Quintana E, Larrainzar E, Arrese Igor C, Gonzalez E. Is N-feedback involved in the inhibition of nitrogen fixation in drought-stressed Medicago truncatula?. J Exp Bot. 2013;64:281-92 pubmed publisher
    ..b>Medicago truncatula plants were symbiotically grown with a split-root system and exposed to gradual water deprivation...
  80. Imin N, Mohd Radzman N, Ogilvie H, Djordjevic M. The peptide-encoding CEP1 gene modulates lateral root and nodule numbers in Medicago truncatula. J Exp Bot. 2013;64:5395-409 pubmed publisher
    ..of MtCEP1, a member of the CEP (C-terminally encoded peptide) signaling peptide family, was examined in Medicago truncatula root development...
  81. Nolan K, Kurdyukov S, Rose R. Expression of the SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE1 (SERK1) gene is associated with developmental change in the life cycle of the model legume Medicago truncatula. J Exp Bot. 2009;60:1759-71 pubmed publisher
    ..As more is learnt about these genes, the view of their role in plant development has broadened. The Medicago truncatula MtSERK1 gene has been associated with somatic embryogenesis and in vitro root formation...
  82. Peel G, Pang Y, Modolo L, Dixon R. The LAP1 MYB transcription factor orchestrates anthocyanidin biosynthesis and glycosylation in Medicago. Plant J. 2009;59:136-49 pubmed publisher
    ..However, PAP1 does not activate anthocyanin biosynthesis in the model legume Medicago truncatula or in alfalfa (Medicago sativa)...
  83. Baier M, Keck M, Gödde V, Niehaus K, Küster H, Hohnjec N. Knockdown of the symbiotic sucrose synthase MtSucS1 affects arbuscule maturation and maintenance in mycorrhizal roots of Medicago truncatula. Plant Physiol. 2010;152:1000-14 pubmed publisher
    The relevance of the symbiosis-induced Medicago truncatula sucrose synthase gene MtSucS1 for an efficient arbuscular mycorrhiza (AM) was studied using two independent antisense lines that displayed up to 10-fold reduced SucS1 levels in ..
  84. Recorbet G, Valot B, Robert F, Gianinazzi Pearson V, Dumas Gaudot E. Identification of in planta-expressed arbuscular mycorrhizal fungal proteins upon comparison of the root proteomes of Medicago truncatula colonised with two Glomus species. Fungal Genet Biol. 2010;47:608-18 pubmed publisher
    ..to enlarge the coverage of in planta expressed-mycorrhiza-related proteins, the root proteome responses of Medicago truncatula upon colonisation with two AM fungi, Glomus mosseae and G...
  85. Mor re Le Paven M, Viau L, Hamon A, Vandecasteele C, Pellizzaro A, Bourdin C, et al. Characterization of a dual-affinity nitrate transporter MtNRT1.3 in the model legume Medicago truncatula. J Exp Bot. 2011;62:5595-605 pubmed publisher
    ..NO(3)(-) was studied by a quantitative genetic approach in a recombinant inbred line (RIL) population of Medicago truncatula. A quantitative trait locus (QTL) on chromosome 5 appeared to be particularly relevant because it was seen ..
  86. Djébali N, Jauneau A, Ameline Torregrosa C, Chardon F, Jaulneau V, Mathe C, et al. Partial resistance of Medicago truncatula to Aphanomyces euteiches is associated with protection of the root stele and is controlled by a major QTL rich in proteasome-related genes. Mol Plant Microbe Interact. 2009;22:1043-55 pubmed publisher
    A pathosystem between Aphanomyces euteiches, the causal agent of pea root rot disease, and the model legume Medicago truncatula was developed to gain insights into mechanisms involved in resistance to this oomycete. The F83005...
  87. Friesen M, Cordeiro M, Penmetsa R, Badri M, Huguet T, Aouani M, et al. Population genomic analysis of Tunisian Medicago truncatula reveals candidates for local adaptation. Plant J. 2010;63:623-35 pubmed publisher
    ..To facilitate association studies in the model legume Medicago truncatula, we present a genome-scale polymorphism scan using existing Affymetrix microarrays...
  88. Cheng X, Peng J, Ma J, Tang Y, Chen R, Mysore K, et al. NO APICAL MERISTEM (MtNAM) regulates floral organ identity and lateral organ separation in Medicago truncatula. New Phytol. 2012;195:71-84 pubmed publisher
    ..In a forward screen of the tobacco retrotransposon1 (Tnt1) insertion population in Medicago truncatula, we isolated a weak allele of the no-apical-meristem mutant mtnam-2...
  89. Kim G, Nam Y. A novel ?(1)-pyrroline-5-carboxylate synthetase gene of Medicago truncatula plays a predominant role in stress-induced proline accumulation during symbiotic nitrogen fixation. J Plant Physiol. 2013;170:291-302 pubmed publisher
    ..Here, we isolated MtP5CS3, a third gene, from Medicago truncatula, whose predicted polypeptide sequence is highly similar to those of previously isolated MtP5CS1 and MtP5CS2 ..
  90. Banasiak J, Biala W, Staszków A, Swarcewicz B, Kepczynska E, Figlerowicz M, et al. A Medicago truncatula ABC transporter belonging to subfamily G modulates the level of isoflavonoids. J Exp Bot. 2013;64:1005-15 pubmed publisher
    ..The experiments described here demonstrated that the level of Medicago truncatula ABCG10 (MtABCG10) mRNA was elevated following application of fungal oligosaccharides to plant roots...
  91. Chen M, Shen X, Li D, Ma L, Dong J, Wang T. Identification and characterization of MtMTP1, a Zn transporter of CDF family, in the Medicago truncatula. Plant Physiol Biochem. 2009;47:1089-94 pubmed publisher
    ..In this report, we have identified MtMTP1, a Zn transporter of the CDF family in the legume model plant Medicago truncatula. The ORF of the MtMTP1 cDNA encodes a protein consisting of 407 amino acid residues with a predicted ..
  92. Zhou R, Jackson L, Shadle G, Nakashima J, Temple S, Chen F, et al. Distinct cinnamoyl CoA reductases involved in parallel routes to lignin in Medicago truncatula. Proc Natl Acad Sci U S A. 2010;107:17803-8 pubmed publisher
    ..We identified two CCR genes in the model legume Medicago truncatula. CCR1 exhibits preference for feruloyl CoA, but CCR2 prefers caffeoyl and 4-coumaroyl CoAs, exhibits ..
  93. Doidy J, Van Tuinen D, Lamotte O, Corneillat M, Alcaraz G, Wipf D. The Medicago truncatula sucrose transporter family: characterization and implication of key members in carbon partitioning towards arbuscular mycorrhizal fungi. Mol Plant. 2012;5:1346-58 pubmed publisher
    ..transport of sucrose from photosynthetic source leaves towards sink organs in the model leguminous species Medicago truncatula. The identification and functional analysis of sugar transporters provide key information on mechanisms ..
  94. Nars A, Rey T, Lafitte C, Vergnes S, Amatya S, Jacquet C, et al. An experimental system to study responses of Medicago truncatula roots to chitin oligomers of high degree of polymerization and other microbial elicitors. Plant Cell Rep. 2013;32:489-502 pubmed publisher
    ..In parallel, we developed a versatile root elicitation bioassay in the model legume Medicago truncatula, using a hydroponic culture system and the Phytophthora ?-glucan elicitor as a control elicitor...
  95. Zhang Q, Blaylock L, Harrison M. Two Medicago truncatula half-ABC transporters are essential for arbuscule development in arbuscular mycorrhizal symbiosis. Plant Cell. 2010;22:1483-97 pubmed publisher
    ..Here, we report a Medicago truncatula mutant, stunted arbuscule (str), in which arbuscule development is impaired and AM symbiosis fails...
  96. Maillet F, Poinsot V, André O, Puech Pages V, Haouy A, Gueunier M, et al. Fungal lipochitooligosaccharide symbiotic signals in arbuscular mycorrhiza. Nature. 2011;469:58-63 pubmed publisher
    ..In the legume Medicago truncatula these signals stimulate root growth and branching by the symbiotic DMI signalling pathway...
  97. Morieri G, Martinez E, Jarynowski A, Driguez H, Morris R, Oldroyd G, et al. Host-specific Nod-factors associated with Medicago truncatula nodule infection differentially induce calcium influx and calcium spiking in root hairs. New Phytol. 2013;200:656-62 pubmed publisher
    ..Sinorhizobium meliloti nodL and nodF mutations additively reduce infection of Medicago truncatula. Nod-factors made by the nodL mutant lack an acetyl group; mutation of nodF causes the nitrogen (N)-linked ..
  98. Grzebelus D, Gładysz M, Macko Podgórni A, Gambin T, Golis B, Rakoczy R, et al. Population dynamics of miniature inverted-repeat transposable elements (MITEs) in Medicago truncatula. Gene. 2009;448:214-20 pubmed publisher
    ..We describe four MITE families related to MtPH transposons mined de novo in the genome of Medicago truncatula, together with one previously described family MITRAV...
  99. Garms S, Köllner T, Boland W. A multiproduct terpene synthase from Medicago truncatula generates cadalane sesquiterpenes via two different mechanisms. J Org Chem. 2010;75:5590-600 pubmed publisher
    ..The multiproduct sesquiterpene synthase MtTPS5 isolated from Medicago truncatula produces 27 products from farnesyl diphosphate (1, FDP)...
  100. Del Giudice J, Cam Y, Damiani I, Fung Chat F, Meilhoc E, Bruand C, et al. Nitric oxide is required for an optimal establishment of the Medicago truncatula-Sinorhizobium meliloti symbiosis. New Phytol. 2011;191:405-17 pubmed publisher
    ..promoter, we detected NO production in the first steps, during infection threads growth, of the Medicago truncatula-Sinorhizobium meliloti symbiotic interaction...