medicago

Summary

Summary: A plant genus of the family FABACEAE. It is distinct from Sweet Clover (MELILOTUS), from Bush Clover (LESPEDEZA), and from Red Clover (TRIFOLIUM).

Top Publications

  1. Glévarec G, Bouton S, Jaspard E, Riou M, Cliquet J, Suzuki A, et al. Respective roles of the glutamine synthetase/glutamate synthase cycle and glutamate dehydrogenase in ammonium and amino acid metabolism during germination and post-germinative growth in the model legume Medicago truncatula. Planta. 2004;219:286-97 pubmed
    ..GDH) in ammonium and amino acid metabolism during germination and post-germinative growth in the model legume Medicago truncatula Gaertn...
  2. Torregrosa C, Cluzet S, Fournier J, Huguet T, Gamas P, Prosperi J, et al. Cytological, genetic, and molecular analysis to characterize compatible and incompatible interactions between Medicago truncatula and Colletotrichum trifolii. Mol Plant Microbe Interact. 2004;17:909-20 pubmed
    In this study, a new pathosystem was established using the model plant Medicago truncatula and Colletotrichum trifolii, the causal agent of anthracnose on Medicago sativa. Screening of a few M...
  3. Bailly X, Olivieri I, Brunel B, Cleyet Marel J, Bena G. Horizontal gene transfer and homologous recombination drive the evolution of the nitrogen-fixing symbionts of Medicago species. J Bacteriol. 2007;189:5223-36 pubmed
    Using nitrogen-fixing Sinorhizobium species that interact with Medicago plants as a model system, we aimed at clarifying how sex has shaped the diversity of bacteria associated with the genus Medicago on the interspecific and ..
  4. Tian C, Garnerone A, Mathieu Demazière C, Masson Boivin C, Batut J. Plant-activated bacterial receptor adenylate cyclases modulate epidermal infection in the Sinorhizobium meliloti-Medicago symbiosis. Proc Natl Acad Sci U S A. 2012;109:6751-6 pubmed publisher
    ..Here we identify in Sinorhizobium meliloti, the Medicago symbiont, a cAMP-signaling regulatory cascade consisting of three receptor-like adenylate cyclases, a Crp-like ..
  5. Xie D, Sharma S, Paiva N, Ferreira D, Dixon R. Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis. Science. 2003;299:396-9 pubmed
    ..We show that the BANYULS (BAN) genes from Arabidopsis thaliana and Medicago truncatula encode anthocyanidin reductase, which converts anthocyanidins to their corresponding 2,3-cis-flavan-3-..
  6. Rodriguez Llorente I, Pérez Hormaeche J, Dary M, Caviedes M, Kondorosi A, Ratet P, et al. Expression of MsPG3-GFP fusions in Medicago truncatula'hairy roots' reveals preferential tip localization of the protein in root hairs. Eur J Biochem. 2003;270:261-9 pubmed
    ..MsPG3 is a Medicago sativa polygalacturonase gene isolated in our laboratory, specifically expressed during the interaction of this ..
  7. Bestel Corre G, Gianinazzi S, Dumas Gaudot E. Impact of sewage sludges on Medicago truncatula symbiotic proteome. Phytochemistry. 2004;65:1651-9 pubmed
    The effects of sewage sludges were investigated on the symbiotic interactions between the model plant Medicago truncatula and the arbuscular mycorrhizal fungus Glomus mosseae or the rhizobial bacteria Sinorhizobium meliloti...
  8. Fedorova M, van de Mortel J, Matsumoto P, Cho J, Town C, VandenBosch K, et al. Genome-wide identification of nodule-specific transcripts in the model legume Medicago truncatula. Plant Physiol. 2002;130:519-37 pubmed
    The Medicago truncatula expressed sequence tag (EST) database (Gene Index) contains over 140,000 sequences from 30 cDNA libraries...
  9. Iturbe Ormaetxe I, Haralampidis K, Papadopoulou K, Osbourn A. Molecular cloning and characterization of triterpene synthases from Medicago truncatula and Lotus japonicus. Plant Mol Biol. 2003;51:731-43 pubmed
    ..Here we report the cloning and characterization of a total of three triterpene synthases from the legume species Medicago truncatula and Lotus japonicus. These include a beta-amyrin synthase from M...
  10. Gubry Rangin C, Bena G, Cleyet Marel J, Brunel B. Definition and evolution of a new symbiovar, sv. rigiduloides, among Ensifer meliloti efficiently nodulating Medicago species. Syst Appl Microbiol. 2013;36:490-6 pubmed publisher
    ..In the present study, the species affiliation of E. meliloti strains trapped from nodules sampled from Medicago rigiduloïdes roots was analyzed using housekeeping recA genes and DNA-DNA hybridization...

Detail Information

Publications82

  1. Glévarec G, Bouton S, Jaspard E, Riou M, Cliquet J, Suzuki A, et al. Respective roles of the glutamine synthetase/glutamate synthase cycle and glutamate dehydrogenase in ammonium and amino acid metabolism during germination and post-germinative growth in the model legume Medicago truncatula. Planta. 2004;219:286-97 pubmed
    ..GDH) in ammonium and amino acid metabolism during germination and post-germinative growth in the model legume Medicago truncatula Gaertn...
  2. Torregrosa C, Cluzet S, Fournier J, Huguet T, Gamas P, Prosperi J, et al. Cytological, genetic, and molecular analysis to characterize compatible and incompatible interactions between Medicago truncatula and Colletotrichum trifolii. Mol Plant Microbe Interact. 2004;17:909-20 pubmed
    In this study, a new pathosystem was established using the model plant Medicago truncatula and Colletotrichum trifolii, the causal agent of anthracnose on Medicago sativa. Screening of a few M...
  3. Bailly X, Olivieri I, Brunel B, Cleyet Marel J, Bena G. Horizontal gene transfer and homologous recombination drive the evolution of the nitrogen-fixing symbionts of Medicago species. J Bacteriol. 2007;189:5223-36 pubmed
    Using nitrogen-fixing Sinorhizobium species that interact with Medicago plants as a model system, we aimed at clarifying how sex has shaped the diversity of bacteria associated with the genus Medicago on the interspecific and ..
  4. Tian C, Garnerone A, Mathieu Demazière C, Masson Boivin C, Batut J. Plant-activated bacterial receptor adenylate cyclases modulate epidermal infection in the Sinorhizobium meliloti-Medicago symbiosis. Proc Natl Acad Sci U S A. 2012;109:6751-6 pubmed publisher
    ..Here we identify in Sinorhizobium meliloti, the Medicago symbiont, a cAMP-signaling regulatory cascade consisting of three receptor-like adenylate cyclases, a Crp-like ..
  5. Xie D, Sharma S, Paiva N, Ferreira D, Dixon R. Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis. Science. 2003;299:396-9 pubmed
    ..We show that the BANYULS (BAN) genes from Arabidopsis thaliana and Medicago truncatula encode anthocyanidin reductase, which converts anthocyanidins to their corresponding 2,3-cis-flavan-3-..
  6. Rodriguez Llorente I, Pérez Hormaeche J, Dary M, Caviedes M, Kondorosi A, Ratet P, et al. Expression of MsPG3-GFP fusions in Medicago truncatula'hairy roots' reveals preferential tip localization of the protein in root hairs. Eur J Biochem. 2003;270:261-9 pubmed
    ..MsPG3 is a Medicago sativa polygalacturonase gene isolated in our laboratory, specifically expressed during the interaction of this ..
  7. Bestel Corre G, Gianinazzi S, Dumas Gaudot E. Impact of sewage sludges on Medicago truncatula symbiotic proteome. Phytochemistry. 2004;65:1651-9 pubmed
    The effects of sewage sludges were investigated on the symbiotic interactions between the model plant Medicago truncatula and the arbuscular mycorrhizal fungus Glomus mosseae or the rhizobial bacteria Sinorhizobium meliloti...
  8. Fedorova M, van de Mortel J, Matsumoto P, Cho J, Town C, VandenBosch K, et al. Genome-wide identification of nodule-specific transcripts in the model legume Medicago truncatula. Plant Physiol. 2002;130:519-37 pubmed
    The Medicago truncatula expressed sequence tag (EST) database (Gene Index) contains over 140,000 sequences from 30 cDNA libraries...
  9. Iturbe Ormaetxe I, Haralampidis K, Papadopoulou K, Osbourn A. Molecular cloning and characterization of triterpene synthases from Medicago truncatula and Lotus japonicus. Plant Mol Biol. 2003;51:731-43 pubmed
    ..Here we report the cloning and characterization of a total of three triterpene synthases from the legume species Medicago truncatula and Lotus japonicus. These include a beta-amyrin synthase from M...
  10. Gubry Rangin C, Bena G, Cleyet Marel J, Brunel B. Definition and evolution of a new symbiovar, sv. rigiduloides, among Ensifer meliloti efficiently nodulating Medicago species. Syst Appl Microbiol. 2013;36:490-6 pubmed publisher
    ..In the present study, the species affiliation of E. meliloti strains trapped from nodules sampled from Medicago rigiduloïdes roots was analyzed using housekeeping recA genes and DNA-DNA hybridization...
  11. Complainville A, Brocard L, Roberts I, Dax E, Sever N, Sauer N, et al. Nodule initiation involves the creation of a new symplasmic field in specific root cells of medicago species. Plant Cell. 2003;15:2778-91 pubmed
    ..Here, we explore cell-to-cell communication processes that occur during nodule initiation in Medicago species and their functional relevance using a combination of fluorescent tracers, electron microscopy, and ..
  12. Paltiel J, Amin R, Gover A, Ori N, Samach A. Novel roles for GIGANTEA revealed under environmental conditions that modify its expression in Arabidopsis and Medicago truncatula. Planta. 2006;224:1255-68 pubmed
    ..a strong response of GI expression to changes in temperature and light, in both Arabidopsis and the model legume Medicago truncatula. Extreme temperatures resulted in increased GI trough levels...
  13. Barran L, Bromfield E, Brown D. Identification and cloning of the bacterial nodulation specificity gene in the Sinorhizobium meliloti--Medicago laciniata symbiosis. Can J Microbiol. 2002;48:765-71 pubmed
    b>Medicago laciniata (cut-leaf medic) is an annual medic that is highly nodulation specific, nodulating only with a restricted range of Sinorhizobium meliloti. e.g...
  14. Yousfi N, Slama I, Ghnaya T, Savoure A, Abdelly C. Effects of water deficit stress on growth, water relations and osmolyte accumulation in Medicago truncatula and M. laciniata populations. C R Biol. 2010;333:205-13 pubmed publisher
    The effects of water stress were investigated in two Tunisian Medicago truncatula populations collected from arid (Mt-173) and sub-humid (Mt-664) climates and two Tunisian M...
  15. Maunoury N, Redondo Nieto M, Bourcy M, Van de Velde W, Alunni B, Laporte P, et al. Differentiation of symbiotic cells and endosymbionts in Medicago truncatula nodulation are coupled to two transcriptome-switches. PLoS ONE. 2010;5:e9519 pubmed publisher
    The legume plant Medicago truncatula establishes a symbiosis with the nitrogen-fixing bacterium Sinorhizobium meliloti which takes place in root nodules...
  16. Bertioli D, Moretzsohn M, Madsen L, Sandal N, Leal Bertioli S, Guimarães P, et al. An analysis of synteny of Arachis with Lotus and Medicago sheds new light on the structure, stability and evolution of legume genomes. BMC Genomics. 2009;10:45 pubmed publisher
    ..The Galegoids are mostly temperate and include clover, fava bean and the model legumes Lotus and Medicago (both with substantially sequenced genomes)...
  17. Journet E, Van Tuinen D, Gouzy J, Crespeau H, Carreau V, Farmer M, et al. Exploring root symbiotic programs in the model legume Medicago truncatula using EST analysis. Nucleic Acids Res. 2002;30:5579-92 pubmed
    ..sequencing and analysis program aimed at characterizing the sets of genes expressed in roots of the model legume Medicago truncatula during interactions with either of two microsymbionts, the nitrogen-fixing bacterium Sinorhizobium ..
  18. Dong Y, Iniguez A, Ahmer B, Triplett E. Kinetics and strain specificity of rhizosphere and endophytic colonization by enteric bacteria on seedlings of Medicago sativa and Medicago truncatula. Appl Environ Microbiol. 2003;69:1783-90 pubmed
    ..Several aspects of the biology of the interaction between these bacteria and alfalfa (Medicago sativa) seedlings are addressed here...
  19. Laurie R, Diwadkar P, Jaudal M, Zhang L, Hecht V, Wen J, et al. The Medicago FLOWERING LOCUS T homolog, MtFTa1, is a key regulator of flowering time. Plant Physiol. 2011;156:2207-24 pubmed publisher
    ..In this study, we characterized five FT-like genes from the model legume, Medicago (Medicago truncatula)...
  20. Maureira Butler I, Pfeil B, Muangprom A, Osborn T, Doyle J. The reticulate history of Medicago (Fabaceae). Syst Biol. 2008;57:466-82 pubmed publisher
    The phylogenetic history of Medicago was examined for 60 accessions from 56 species using two nuclear genes (CNGC5 and beta-cop) and one mitochondrial region (rpS14-cob)...
  21. Yan H, Mudge J, Kim D, Shoemaker R, Cook D, Young N. Comparative physical mapping reveals features of microsynteny between Glycine max, Medicago truncatula, and Arabidopsis thaliana. Genome. 2004;47:141-55 pubmed
    To gain insight into genomic relationships between soybean (Glycine max) and Medicago truncatula, eight groups of bacterial artificial chromosome (BAC) contigs, together spanning 2.60 million base pairs (Mb) in G. max and 1.56 Mb in M...
  22. Ho Huu J, Ronfort J, De Mita S, Bataillon T, Hochu I, Weber A, et al. Contrasted patterns of selective pressure in three recent paralogous gene pairs in the Medicago genus (L.). BMC Evol Biol. 2012;12:195 pubmed publisher
    ..known to be involved in an interaction with symbiotic bacteria and were recently duplicated in the history of the Medicago genus (Fabaceae)...
  23. Gannabathula S, Skinner M, Rosendale D, Greenwood J, Mutukumira A, Steinhorn G, et al. Arabinogalactan proteins contribute to the immunostimulatory properties of New Zealand honeys. Immunopharmacol Immunotoxicol. 2012;34:598-607 pubmed publisher
    ..Factors in honey that improve wound healing are poorly understood, but are thought to include lipopolysaccharide (LPS), apalbumin-1 and -2, and a 5.8?kDa component that stimulate cytokine release from macrophages...
  24. Deavours B, Liu C, Naoumkina M, Tang Y, Farag M, Sumner L, et al. Functional analysis of members of the isoflavone and isoflavanone O-methyltransferase enzyme families from the model legume Medicago truncatula. Plant Mol Biol. 2006;62:715-33 pubmed
    ..studies have identified two distinct O-methyltransferases (OMTs) implicated in isoflavonoid biosynthesis in Medicago species, a 7-OMT methylating the A-ring 7-hydroxyl of the isoflavone daidzein and a 4'-OMT methylating the B-ring ..
  25. Middleton P, Jakab J, Penmetsa R, Starker C, Doll J, Kalo P, et al. An ERF transcription factor in Medicago truncatula that is essential for Nod factor signal transduction. Plant Cell. 2007;19:1221-34 pubmed
    ..We propose that ERN is a component of the Nod factor signal transduction pathway and functions downstream of DMI3 to activate nodulation gene expression...
  26. Kevei Z, Vinardell J, Kiss G, Kondorosi A, Kondorosi E. Glycine-rich proteins encoded by a nodule-specific gene family are implicated in different stages of symbiotic nodule development in Medicago spp. Mol Plant Microbe Interact. 2002;15:922-31 pubmed
    ..genes encoding small proteins with significantly high glycine content have been identified from root nodules of Medicago sativa...
  27. Castonguay Y, Cloutier J, Bertrand A, Michaud R, Laberge S. SRAP polymorphisms associated with superior freezing tolerance in alfalfa (Medicago sativa spp. sativa). Theor Appl Genet. 2010;120:1611-9 pubmed publisher
    ..Homology search gave matches with BAC clones from syntenic Medicago truncatula for the four SRAP fragments...
  28. Genre A, Chabaud M, Timmers T, Bonfante P, Barker D. Arbuscular mycorrhizal fungi elicit a novel intracellular apparatus in Medicago truncatula root epidermal cells before infection. Plant Cell. 2005;17:3489-99 pubmed
    ..evaluate the role played by the host plant during AM infection, we have studied in vivo cellular dynamics within Medicago truncatula root epidermal cells using green fluorescent protein labeling of both the plant cytoskeleton and the ..
  29. Campalans A, Kondorosi A, Crespi M. Enod40, a short open reading frame-containing mRNA, induces cytoplasmic localization of a nuclear RNA binding protein in Medicago truncatula. Plant Cell. 2004;16:1047-59 pubmed publisher
    ..A novel RNA binding protein interacting with the enod40 RNA, MtRBP1 (for Medicago truncatula RNA Binding Protein 1), was identified using a yeast three-hybrid screening...
  30. Janczarek M, Skorupska A. Regulation of pssA and pssB gene expression in Rhizobium leguminosarum bv. trifolii in response to environmental factors. Antonie Van Leeuwenhoek. 2004;85:217-27 pubmed
    ..The pssB-gusA fusion was expressed mainly in the infection zone and interzone of the nodule and the pattern of expression was dependent on the plant phosphate availability...
  31. Pivato B, Mazurier S, Lemanceau P, Siblot S, Berta G, Mougel C, et al. Medicago species affect the community composition of arbuscular mycorrhizal fungi associated with roots. New Phytol. 2007;176:197-210 pubmed
    ..LSU rDNA) and quantitative polymerase chain reaction (qPCR) were combined to assess the impact of four annual Medicago species (Medicago laciniata, Medicago murex, Medicago polymorpha and Medicago truncatula) on the genetic ..
  32. Ané J, Kiss G, Riely B, Penmetsa R, Oldroyd G, Ayax C, et al. Medicago truncatula DMI1 required for bacterial and fungal symbioses in legumes. Science. 2004;303:1364-7 pubmed
    ..Here, we describe the cloning and characterization of one such gene from the legume Medicago truncatula...
  33. Staehelin C, Charon C, Boller T, Crespi M, Kondorosi A. Medicago truncatula plants overexpressing the early nodulin gene enod40 exhibit accelerated mycorrhizal colonization and enhanced formation of arbuscules. Proc Natl Acad Sci U S A. 2001;98:15366-71 pubmed
    ..b>Medicago truncatula plants overexpressing enod40 exhibited stimulated mycorrhizal colonization in comparison with control ..
  34. Kosuta S, Chabaud M, Lougnon G, Gough C, Dénarié J, Barker D, et al. A diffusible factor from arbuscular mycorrhizal fungi induces symbiosis-specific MtENOD11 expression in roots of Medicago truncatula. Plant Physiol. 2003;131:952-62 pubmed
    Using dual cultures of arbuscular mycorrhizal (AM) fungi and Medicago truncatula separated by a physical barrier, we demonstrate that hyphae from germinating spores produce a diffusible factor that is perceived by roots in the absence of ..
  35. Navarro Gochicoa M, Camut S, Timmers A, Niebel A, Herve C, Boutet E, et al. Characterization of four lectin-like receptor kinases expressed in roots of Medicago truncatula. Structure, location, regulation of expression, and potential role in the symbiosis with Sinorhizobium meliloti. Plant Physiol. 2003;133:1893-910 pubmed
    ..role of LecRK (lectin-like receptor kinase) genes in the legumerhizobia symbiosis, we have characterized the four Medicago truncatula Gaernt. LecRK genes that are most highly expressed in roots...
  36. Engstrom E, Ehrhardt D, Mitra R, Long S. Pharmacological analysis of nod factor-induced calcium spiking in Medicago truncatula. Evidence for the requirement of type IIA calcium pumps and phosphoinositide signaling. Plant Physiol. 2002;128:1390-401 pubmed
    ..The purpose of this screening was 2-fold: to implicate enzymes required for Nod factor-induced calcium spiking in Medicago sp...
  37. Thoquet P, Gherardi M, Journet E, Kereszt A, Ané J, Prosperi J, et al. The molecular genetic linkage map of the model legume Medicago truncatula: an essential tool for comparative legume genomics and the isolation of agronomically important genes. BMC Plant Biol. 2002;2:1 pubmed
    The legume Medicago truncatula has emerged as a model plant for the molecular and genetic dissection of various plant processes involved in rhizobial, mycorrhizal and pathogenic plant-microbe interactions...
  38. Watson B, Asirvatham V, Wang L, Sumner L. Mapping the proteome of barrel medic (Medicago truncatula). Plant Physiol. 2003;131:1104-23 pubmed
    A survey of six organ-/tissue-specific proteomes of the model legume barrel medic (Medicago truncatula) was performed...
  39. Salzer P, Feddermann N, Wiemken A, Boller T, Staehelin C. Sinorhizobium meliloti-induced chitinase gene expression in Medicago truncatula ecotype R108-1: a comparison between symbiosis-specific class V and defence-related class IV chitinases. Planta. 2004;219:626-38 pubmed
    The Medicago truncatula (Gaertn.) ecotypes Jemalong A17 and R108-1 differ in Sinorhizobium meliloti-induced chitinase gene expression...
  40. Bestel Corre G, Dumas Gaudot E, Poinsot V, Dieu M, Dierick J, van T, et al. Proteome analysis and identification of symbiosis-related proteins from Medicago truncatula Gaertn. by two-dimensional electrophoresis and mass spectrometry. Electrophoresis. 2002;23:122-37 pubmed
    ..root protein profiles was studied by two-dimensional gel electrophoresis and silver staining in the model plant Medicago truncatula, inoculated either with the arbuscular mycorrhizal fungus Glomus mosseae or with the nitrogen fixing ..
  41. Ramu S, Peng H, Cook D. Nod factor induction of reactive oxygen species production is correlated with expression of the early nodulin gene rip1 in Medicago truncatula. Mol Plant Microbe Interact. 2002;15:522-8 pubmed
    ..Taken together, these results suggest that ROS production is a consequence of specific Nod factor perception and implicate H2O2 produced during this response as a mediator of Nod factor-induced rip1 expression...
  42. Stochmal A, Simonet A, Macias F, Oleszek W. Alfalfa (Medicago sativa L.) flavonoids. 2. Tricin and chrysoeriol glycosides from aerial parts. J Agric Food Chem. 2001;49:5310-4 pubmed
    ..Two previously identified alfalfa flavones, 7-O-beta-D-glucuronopyranosidetricin and 7-O-[beta-D-glucuronopyranosyl(1-->2)-O-beta-D-glucuronopyranoside]tricin, were also isolated...
  43. Rose R, Wang X, Nolan K, Rolfe B. Root meristems in Medicago truncatula tissue culture arise from vascular-derived procambial-like cells in a process regulated by ethylene. J Exp Bot. 2006;57:2227-35 pubmed
    Leaf explants of Medicago truncatula were used to investigate the origins of auxin-induced root formation...
  44. Esseling J, Lhuissier F, Emons A. A nonsymbiotic root hair tip growth phenotype in NORK-mutated legumes: implications for nodulation factor-induced signaling and formation of a multifaceted root hair pocket for bacteria. Plant Cell. 2004;16:933-44 pubmed
    The Medicago truncatula Does not Make Infections (DMI2) mutant is mutated in the nodulation receptor-like kinase, NORK...
  45. Ané J, Levy J, Thoquet P, Kulikova O, de Billy F, Penmetsa V, et al. Genetic and cytogenetic mapping of DMI1, DMI2, and DMI3 genes of Medicago truncatula involved in Nod factor transduction, nodulation, and mycorrhization. Mol Plant Microbe Interact. 2002;15:1108-18 pubmed
    The DMI1, DMI2, and DMI3 genes of Medicago truncatula, which are required for both nodulation and mycorrhization, control early steps of Nod factor signal transduction...
  46. Soares N, Wojtkowska J, Jackson P. A proteomic analysis of the wound response in Medicago leaves reveals the early activation of a ROS-sensitive signal pathway. J Proteomics. 2011;74:1411-20 pubmed publisher
    Wounded Medicago truncatula leaves produce a burst of O(2)(-) (phase I) between 1 and 15 min, then of O(2)(-) and H(2)O(2) (phase II) between 1 and 3 h...
  47. López Millán A, Ellis D, Grusak M. Identification and characterization of several new members of the ZIP family of metal ion transporters in Medicago truncatula. Plant Mol Biol. 2004;54:583-96 pubmed
    ..metal transport in plants, we have identified cDNAs for six new metal transporters in the model legume Medicago truncatula...
  48. Carvalho H, Lopes Cardoso I, Lima L, Melo P, Cullimore J. Nodule-specific modulation of glutamine synthetase in transgenic Medicago truncatula leads to inverse alterations in asparagine synthetase expression. Plant Physiol. 2003;133:243-52 pubmed
    Transgenic Medicago truncatula plants were produced harboring chimeric gene constructs of the glutamine synthetase (GS) cDNA clones (MtGS1a or MtGS1b) fused in sense or antisense orientation to the nodule-specific leghemoglobin promoter ..
  49. Tivoli B, Baranger A, Sivasithamparam K, Barbetti M. Annual Medicago: from a model crop challenged by a spectrum of necrotrophic pathogens to a model plant to explore the nature of disease resistance. Ann Bot. 2006;98:1117-28 pubmed
    Annual Medicago spp., including M...
  50. Griffiths A, Barrett B, Simon D, Khan A, Bickerstaff P, Anderson C, et al. An integrated genetic linkage map for white clover (Trifolium repens L.) with alignment to Medicago. BMC Genomics. 2013;14:388 pubmed publisher
    ..Development of these tools provides for a consistent framework map of the white clover genome, and facilitates in silico alignment with the model forage legume, Medicago truncatula.
  51. Chatelain E, Hundertmark M, Leprince O, Le Gall S, Satour P, Deligny Penninck S, et al. Temporal profiling of the heat-stable proteome during late maturation of Medicago truncatula seeds identifies a restricted subset of late embryogenesis abundant proteins associated with longevity. Plant Cell Environ. 2012;35:1440-55 pubmed publisher
    ..this, a reference map of LEA proteins was established by proteomics on a hydrophilic protein fraction from mature Medicago truncatula seeds and identified 35 polypeptides encoded by 16 LEA genes...
  52. Janczarek M, Jaroszuk Sciseł J, Skorupska A. Multiple copies of rosR and pssA genes enhance exopolysaccharide production, symbiotic competitiveness and clover nodulation in Rhizobium leguminosarum bv. trifolii. Antonie Van Leeuwenhoek. 2009;96:471-86 pubmed publisher
    ..Overall, experimental evidence is provided that increased amount of EPS beneficially affects R. leguminosarum bv. trifolii competitiveness and symbiosis with clover...
  53. Yan H, Mudge J, Kim D, Larsen D, Shoemaker R, Cook D, et al. Estimates of conserved microsynteny among the genomes of Glycine max, Medicago truncatula and Arabidopsis thaliana. Theor Appl Genet. 2003;106:1256-65 pubmed
    ..To estimate the level of microsynteny between Medicago truncatula (Mt) and Glycine max (soybean), and also among homoeologous segments of soybean, we used a ..
  54. Küster H, Hohnjec N, Krajinski F, El Y, Manthey K, Gouzy J, et al. Construction and validation of cDNA-based Mt6k-RIT macro- and microarrays to explore root endosymbioses in the model legume Medicago truncatula. J Biotechnol. 2004;108:95-113 pubmed
    ..construct macro- and microarray tools suitable for expression profiling in root endosymbioses of the model legume Medicago truncatula, we PCR-amplified a total of 6048 cDNA probes representing genes expressed in uninfected roots, ..
  55. Villegas M, Rome S, Mauré L, Domergue O, Gardan L, Bailly X, et al. Nitrogen-fixing sinorhizobia with Medicago laciniata constitute a novel biovar (bv. medicaginis) of S. meliloti. Syst Appl Microbiol. 2006;29:526-38 pubmed
    Sixty-eight new rhizobial isolates were obtained from root-nodules of Medicago laciniata and from Mediterranean soils in Tunisia and France...
  56. Eujayl I, Sledge M, Wang L, May G, Chekhovskiy K, Zwonitzer J, et al. Medicago truncatula EST-SSRs reveal cross-species genetic markers for Medicago spp. Theor Appl Genet. 2004;108:414-22 pubmed
    ..From over 147,000 ESTs of Medicago truncatula, we have identified 4,384 ESTs containing perfect simple sequence repeats (EST-SSR) of di-, tri-, ..
  57. Tadege M, Ratet P, Mysore K. Insertional mutagenesis: a Swiss Army knife for functional genomics of Medicago truncatula. Trends Plant Sci. 2005;10:229-35 pubmed
    ..Over the past decade, Medicago truncatula has been selected as a model plant in which to study biological processes that are unique and ..
  58. de Carvalho Niebel F, Timmers A, Chabaud M, Defaux Petras A, Barker D. The Nod factor-elicited annexin MtAnn1 is preferentially localised at the nuclear periphery in symbiotically activated root tissues of Medicago truncatula. Plant J. 2002;32:343-52 pubmed
    The Medicago truncatula MtAnn1 gene, encoding a putative annexin, is transcriptionally activated in root tissues in response to rhizobial Nod factors...
  59. Harrison M, Dewbre G, Liu J. A phosphate transporter from Medicago truncatula involved in the acquisition of phosphate released by arbuscular mycorrhizal fungi. Plant Cell. 2002;14:2413-29 pubmed
    ..In Medicago truncatula, a model legume used widely for studies of root symbioses, it is apparent that the phosphate ..
  60. Rosato M, Galián J, Rosselló J. Amplification, contraction and genomic spread of a satellite DNA family (E180) in Medicago (Fabaceae) and allied genera. Ann Bot. 2012;109:773-82 pubmed publisher
    ..Here we assess the presence and physical distribution of the repetitive DNA E180 family in Medicago and allied genera...
  61. Shaw S, Long S. Nod factor elicits two separable calcium responses in Medicago truncatula root hair cells. Plant Physiol. 2003;131:976-84 pubmed
    ..Here, we characterize early calcium responses of wild-type and mutant Medicago truncatula plants to nodulation factors produced by the bacterial symbiont Sinorhizobium meliloti using a dual-..
  62. Yoder J, Briskine R, Mudge J, Farmer A, Paape T, STEELE K, et al. Phylogenetic signal variation in the genomes of Medicago (Fabaceae). Syst Biol. 2013;62:424-38 pubmed publisher
    ..We collected whole-genome sequence data from 29 taxa in the legume genus Medicago, then aligned these sequences to the Medicago truncatula reference genome to confidently identify 87 596 variable ..
  63. Roudier F, Fedorova E, Lebris M, Lecomte P, Györgyey J, Vaubert D, et al. The Medicago species A2-type cyclin is auxin regulated and involved in meristem formation but dispensable for endoreduplication-associated developmental programs. Plant Physiol. 2003;131:1091-103 pubmed
    ..Here, we investigated the function and regulation of an alfalfa (Medicago sativa) A2-type cyclin in three distinct root developmental programs: in primary and secondary root development, ..
  64. Bena G, Lyet A, Huguet T, Olivieri I. Medicago-Sinorhizobium symbiotic specificity evolution and the geographic expansion of Medicago. J Evol Biol. 2005;18:1547-58 pubmed
    The legume genus Medicago interacts with soil bacteria commonly referred to as rhizobia, in a nitrogen fixing symbiosis...
  65. Amor B, Shaw S, Oldroyd G, Maillet F, Penmetsa R, Cook D, et al. The NFP locus of Medicago truncatula controls an early step of Nod factor signal transduction upstream of a rapid calcium flux and root hair deformation. Plant J. 2003;34:495-506 pubmed
    ..Using nodulation-defective (Nod-) mutants of Medicago truncatula to study the mechanisms controlling Nod factor perception and signalling, we have previously ..
  66. Ovchinnikova E, Journet E, Chabaud M, Cosson V, Ratet P, Duc G, et al. IPD3 controls the formation of nitrogen-fixing symbiosomes in pea and Medicago Spp. Mol Plant Microbe Interact. 2011;24:1333-44 pubmed publisher
    ..Two legume mutants that are most strongly impaired in their ability to form symbiosomes are sym1/TE7 in Medicago truncatula and sym33 in Pisum sativum...
  67. Penmetsa R, Frugoli J, Smith L, Long S, Cook D. Dual genetic pathways controlling nodule number in Medicago truncatula. Plant Physiol. 2003;131:998-1008 pubmed
    We report the isolation and characterization of a new Medicago truncatula hyper-nodulation mutant, designated sunn (super numeric nodules)...
  68. Zhu H, Kim D, Baek J, Choi H, Ellis L, Küester H, et al. Syntenic relationships between Medicago truncatula and Arabidopsis reveal extensive divergence of genome organization. Plant Physiol. 2003;131:1018-26 pubmed
    Arabidopsis and Medicago truncatula represent sister clades within the dicot subclass Rosidae...
  69. Gomez S, Cox M, Bede J, Inoue K, Alborn H, Tumlinson J, et al. Lepidopteran herbivory and oral factors induce transcripts encoding novel terpene synthases in Medicago truncatula. Arch Insect Biochem Physiol. 2005;58:114-27 pubmed
    ..Sequences predicted to encode terpene synthases were selected from an expressed sequence tag (EST) database of Medicago truncatula. Four putative terpene synthase clones (MtTps1-MtTps4), originating from a chewing insect-damaged M...
  70. Navarro Gochicoa M, Camut S, Niebel A, Cullimore J. Expression of the apyrase-like APY1 genes in roots of Medicago truncatula is induced rapidly and transiently by stress and not by Sinorhizobium meliloti or Nod factors. Plant Physiol. 2003;131:1124-36 pubmed
    The model legume Medicago truncatula contains at least six apyrase-like genes, five of which (MtAPY1;1, MtAPY1;2, MtAPY1;3, MtAPY1;4, and MtAPY1;5) are members of a legume-specific family, whereas a single gene (MtAPY2) has closer ..
  71. Burleigh S, Kristensen B, Bechmann I. A plasma membrane zinc transporter from Medicago truncatula is up-regulated in roots by Zn fertilization, yet down-regulated by arbuscular mycorrhizal colonization. Plant Mol Biol. 2003;52:1077-88 pubmed
    Here we present a Zn transporter cDNA named MtZIP2 from the model legume Medicago truncatula...
  72. Sreedhar L, Wolkers W, Hoekstra F, Bewley J. In vivo characterization of the effects of abscisic acid and drying protocols associated with the acquisition of desiccation tolerance in alfalfa (Medicago sativa L.) somatic embryos. Ann Bot. 2002;89:391-400 pubmed
    Although somatic embryos of alfalfa (Medicago sativa L...
  73. Zhu H, Cannon S, Young N, Cook D. Phylogeny and genomic organization of the TIR and non-tIR NBS-LRR resistance gene family in Medicago truncatula. Mol Plant Microbe Interact. 2002;15:529-39 pubmed
    ..Moreover, sequences from species within the closely related Trifoleae and Viceae tribes (e.g., Medicago and Pisum spp.) tended to be cophyletic and distinct from sequences of Phaseoleae species (e.g...
  74. Pecetti L, Biazzi E, Tava A. Variation in saponin content during the growing season of spotted medic [Medicago arabica (L.) Huds.]. J Sci Food Agric. 2010;90:2405-10 pubmed publisher
    Spotted medic [Medicago arabica (L.) Huds.] is a minor forage species containing saponins which are reported to be biologically active...
  75. Zhang S, Zhao C, Lamb E. Cotyledon damage affects seed number through final plant size in the annual grassland species Medicago lupulina. Ann Bot. 2011;107:437-42 pubmed publisher
    ..Here the direct and indirect mechanisms linking cotyledon damage and plant fitness in the annual species Medicago lupulina are examined.
  76. Mantiri F, Kurdyukov S, Lohar D, Sharopova N, Saeed N, Wang X, et al. The transcription factor MtSERF1 of the ERF subfamily identified by transcriptional profiling is required for somatic embryogenesis induced by auxin plus cytokinin in Medicago truncatula. Plant Physiol. 2008;146:1622-36 pubmed publisher
    Transcriptional profiling of embryogenic callus produced from Medicago truncatula mesophyll protoplasts indicated up-regulation of ethylene biosynthesis and ethylene response genes...
  77. Guo D, Chen F, Dixon R. Monolignol biosynthesis in microsomal preparations from lignifying stems of alfalfa (Medicago sativa L.). Phytochemistry. 2002;61:657-67 pubmed
    Microsomal preparations from lignifying stems of alfalfa (Medicago sativa L...