astragalus membranaceus

Summary

Summary: A plant species of the Astragalus genus which is source of Huang qi preparation used in TRADITIONAL CHINESE MEDICINE.

Top Publications

  1. Yu S, Ouyang H, Yang J, Huang X, Yang T, Duan J, et al. Subchronic toxicity studies of Radix Astragali extract in rats and dogs. J Ethnopharmacol. 2007;110:352-5 pubmed
    Radix Astragali extract (RAE) is obtained from Astragalus membranaceus. It consists of Astragalus polysaccharide and Astragalus membranaceus saponins...
  2. Mao S, Cheng K, Zhou Y. [Modulatory effect of Astragalus membranaceus on Th1/Th2 cytokine in patients with herpes simplex keratitis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004;24:121-3 pubmed
    To explore the influence of Astragalus membranaceus (AM) on serum cytokines, Th1, including interleukin-2 (IL-2) and gamma-interferon (gamma-IFN), and Th2, including interleukin-4 (IL-4) and interleukin-10 (IL-10), in patients with ..
  3. Huang L, Yan Q, Kopparapu N, Jiang Z, Sun Y. Astragalus membranaceus lectin (AML) induces caspase-dependent apoptosis in human leukemia cells. Cell Prolif. 2012;45:15-21 pubmed publisher
    ..anti-proliferation of human cancer cell lines by a galactose-binding lectin (AML), from a Chinese herb, ASTRAGALUS MEMBRANACEUS: In the present study, detailed investigations into the mechanism of such anti-proliferation properties ..
  4. Zhang L, Yang Y, Wang Y, Gao X. Astragalus membranaceus extract promotes neovascularisation by VEGF pathway in rat model of ischemic injury. Pharmazie. 2011;66:144-50 pubmed
    b>Astragalus membranaceus extract (AME) is a widely used herbal product for the treatment of cardiovascular diseases in China...
  5. Ko J, Chik C. The protective action of radix Astragalus membranaceus against hapten-induced colitis through modulation of cytokines. Cytokine. 2009;47:85-90 pubmed publisher
    b>Astragalus membranaceus is a medicinal herb with potential immunomodulatory property, which has been used in treating colitis-related diarrhea...
  6. Cho W, Leung K. In vitro and in vivo anti-tumor effects of Astragalus membranaceus. Cancer Lett. 2007;252:43-54 pubmed
    b>Astragalus membranaceus, a commonly used Chinese medicinal plant, has been shown to be capable of restoring the impaired T cell functions in cancer patients. In this study, the in vitro and in vivo anti-tumor effects of A...
  7. Lee D, Noh H, Choi J, Lee K, Lee M, Lee J, et al. Anti-inflammatory cycloartane-type saponins of Astragalus membranaceus. Molecules. 2013;18:3725-32 pubmed publisher
    A new cycloartane-type triterpene glycoside, agroastragaloside V (1) was isolated from the roots of Astragalus membranaceus. The structure was identified as 3-O-?-(2'-O-acetyl)-D-xylopyranosyl-6-O-?-D-glucopyranosyl-(24S)-3?,6?,24?,25-..
  8. Sheng B, Chen X, Zhao J, He D, Nan X. Astragalus membranaceus reduces free radical-mediated injury to renal tubules in rabbits receiving high-energy shock waves. Chin Med J (Engl). 2005;118:43-9 pubmed
    ..This study aimed at investigating the effects of Astragalus membranaceus, a traditional Chinese medicinal herb, on free radical-mediated HESW-induced damage to renal tubules in a ..
  9. Wojcikowski K, Wohlmuth H, Johnson D, Gobe G. Effect of Astragalus membranaceus and Angelica sinensis combined with Enalapril in rats with obstructive uropathy. Phytother Res. 2010;24:875-84 pubmed publisher
    ..Combined extract of Astragalus membranaceus and Angelica sinensis (A&A) is a traditional antifibrotic agent in China...

More Information

Publications62

  1. Mao X, Yu F, Wang N, Wu Y, Zou F, Wu K, et al. Hypoglycemic effect of polysaccharide enriched extract of Astragalus membranaceus in diet induced insulin resistant C57BL/6J mice and its potential mechanism. Phytomedicine. 2009;16:416-25 pubmed publisher
    ..We have shown that APS has beneficial effects on insulin resistance and hyperglycemia. The mechanism is related to the alleviation of ER stress and insulin resistance under hyperglycemia conditions...
  2. Cui R, He J, Wang B, Zhang F, Chen G, Yin S, et al. Suppressive effect of Astragalus membranaceus Bunge on chemical hepatocarcinogenesis in rats. Cancer Chemother Pharmacol. 2003;51:75-80 pubmed
    b>Astragalus membranaceus (AM) has been widely used for treating liver diseases in traditional Chinese medicine. Experimental evidence indicates that it has antitumor potential...
  3. Li W, Fitzloff J. Determination of astragaloside IV in Radix astragali (Astragalus membranaceus var. monghulicus) using high-performance liquid chromatography with evaporative light-scattering detection. J Chromatogr Sci. 2001;39:459-62 pubmed
    ..4 bar. The detection limit (signal-to-noise ratio > 5) of astragaloside IV is 40 ng on-column...
  4. Yip P, Kwan H. Molecular identification of Astragalus membranaceus at the species and locality levels. J Ethnopharmacol. 2006;106:222-9 pubmed
    b>Astragalus membranaceus (Fisch.) Bunge, a commonly used Chinese medicinal material, from certain localities contains more favourable trace elements and fewer harmful trace elements than those from other localities...
  5. Ko J, Lam F, Cheung A. Amelioration of experimental colitis by Astragalus membranaceus through anti-oxidation and inhibition of adhesion molecule synthesis. World J Gastroenterol. 2005;11:5787-94 pubmed
    To investigate the protective effects of Astragalus membranaceus (Am) against hapten-induced colitis in male Sprague-Dawley rats as well as its underlying mechanism.
  6. Hei Z, Huang H, Zhang J, Chen B, Li X. Protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury after hemorrhagic shock in rats. World J Gastroenterol. 2005;11:4986-91 pubmed
    To study the protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury and its mechanism after hemorrhagic shock in rats.
  7. Sun W, Wang L, Liu H, Li X, Wei W. A standardized extract from Paeonia lactiflora and Astragalus membranaceus attenuates liver fibrosis induced by porcine serum in rats. Int J Mol Med. 2012;29:491-8 pubmed publisher
    Paeonia lactiflora and Astragalus membranaceus are two popular traditional Chinese medicines, commonly used in Chinese herb prescription to treat liver disease...
  8. Wang T, Sun Y, Jin L, Xu Y, Wang L, Ren T, et al. Enhancement of non-specific immune response in sea cucumber (Apostichopus japonicus) by Astragalus membranaceus and its polysaccharides. Fish Shellfish Immunol. 2009;27:757-62 pubmed publisher
    ..administration of different preparations (conventional fine powder [CP] and superfine powder [SP]) of Astragalus membranaceus root or its polysaccharides (APS) in sea cucumber (Apostichopus japonicus) was investigated...
  9. Peng X, Wu X, Zhang G, Yi Z, Zheng W, He X, et al. [Regulatory effect of Astragalus membranaceus on the immune disorder in rats with IgA nephropathy]. Zhonghua Er Ke Za Zhi. 2008;46:55-60 pubmed
    To study the regulattory effect of Astragalus membranaceus on immune disturbance of the rats with IgA nephropathy.
  10. Li W, Sun Y, Yan X, Yang S, Song S, Lee Y, et al. NF-?B inhibitory activity of sucrose fatty acid esters and related constituents from Astragalus membranaceus. J Agric Food Chem. 2013;61:7081-8 pubmed publisher
    ..four galactosyl acylglycerols (7-10), and two sphingolipids (11 and 12), were isolated from the roots of Astragalus membranaceus . Their structures were identified on the basis of spectroscopic analysis...
  11. Ahmed M, Hou S, Battaglia M, Picken M, Leehey D. Treatment of idiopathic membranous nephropathy with the herb Astragalus membranaceus. Am J Kidney Dis. 2007;50:1028-32 pubmed
    ..After more than 2 years of unremitting nephrosis, she began therapy with the herb Astragalus membranaceus, used by traditional Chinese physicians to treat various immune disorders, including glomerulonephritis...
  12. Sun Y, Jin L, Wang T, Xue J, Liu G, Li X, et al. Polysaccharides from Astragalus membranaceus promote phagocytosis and superoxide anion (O2-) production by coelomocytes from sea cucumber Apostichopus japonicus in vitro. Comp Biochem Physiol C Toxicol Pharmacol. 2008;147:293-8 pubmed publisher
    ..It suggested that immunocytes activity in A. japonicus decreased with the temperature increasing from 18 degrees C to 25 degrees C, and APS could be an effective immunostimulant to enhance phagocytic activity and O(2)(-) production...
  13. Du M, Wu X, Ding J, Hu Z, White K, Branford White C. Astragaloside IV and polysaccharide production by hairy roots of Astragalus membranaceus in bioreactors. Biotechnol Lett. 2003;25:1853-6 pubmed
    Hairy roots of Astragalus membranaceus were grown in bioreactors up to 30 l for 20 d. Cultures from a 30 l airlift bioreactor gave 11.5 g l dry wt with 1...
  14. Wu Y, Ou Yang J, Wu K, Wang Y, Zhou Y, Wen C. Hypoglycemic effect of Astragalus polysaccharide and its effect on PTP1B. Acta Pharmacol Sin. 2005;26:345-52 pubmed
    To examine the effects of Astragalus polysaccharide (APS), a component of an aqueous extract of Astragalus membranaceus roots, on protein tyrosine phosphatase 1B (PTP1B), a negative regulator of insulin-receptor (IR) signal transduction, ..
  15. Kim J, Kim M, Lee E, Lee C. Inhibitory effects of calycosin isolated from the root of Astragalus membranaceus on melanin biosynthesis. Biol Pharm Bull. 2009;32:264-8 pubmed
    ..A methanol extract of Astragalus membranaceus showed inhibitory activity against mushroom tyrosinase...
  16. Zhang W, Chen H, Zhang C, Liu R, Li H, Chen H. Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro. Planta Med. 2006;72:4-8 pubmed
    Astragaloside IV is the major active constituent of Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases in China...
  17. Zhang J, Xie X, Li C, Fu P. Systematic review of the renal protective effect of Astragalus membranaceus (root) on diabetic nephropathy in animal models. J Ethnopharmacol. 2009;126:189-96 pubmed publisher
    ..Recent experimental studies have shown that Astragalus membranaceus (AM) (root) has an inhibitory effect on the oxidative stress that characterizes early DN...
  18. Zhu X, Zhu B. Mechanisms by which Astragalus membranaceus injection regulates hematopoiesis in myelosuppressed mice. Phytother Res. 2007;21:663-7 pubmed
    The aim of this study was to investigate the mechanism underlying the effects of Astragalus membranaceus injection (AMI) on myelopoiesis in myelosuppressed mice...
  19. Lai P, Chan J, Wu S, Cheng L, Ho G, Lau C, et al. Anti-inflammatory activities of an active fraction isolated from the root of Astragalus membranaceus in RAW 264.7 macrophages. Phytother Res. 2014;28:395-404 pubmed publisher
    The root of Astragalus membranaceus (AR), which has been widely used in Traditional Chinese herbal formulae for treating foot ulcer, was found to exhibit anti-inflammatory property, but its molecular mechanism still remains unknown...
  20. Meng L, Qu L, Tang J, Cai S, Wang H, Li X. A combination of Chinese herbs, Astragalus membranaceus var. mongholicus and Angelica sinensis, enhanced nitric oxide production in obstructed rat kidney. Vascul Pharmacol. 2007;47:174-83 pubmed
    ..The decoction (A&A) of a combination of roots of two Chinese herbs, Astragalus membranaceus var...
  21. Ma W, Nomura M, Takahashi Nishioka T, Kobayashi S. Combined effects of fangchinoline from Stephania tetrandra Radix and formononetin and calycosin from Astragalus membranaceus Radix on hyperglycemia and hypoinsulinemia in streptozotocin-diabetic mice. Biol Pharm Bull. 2007;30:2079-83 pubmed
    The anti-hyperglycemic action of Stephania tetrandra Radix (Stephania) is potentiated by Astragalus membranaceus BUNGE Radix (Astragali) in streptozotocin (STZ)-diabetic ddY mice (Tsutsumi et al., Biol. Pharm. Bull., 26, 313 (2003))...
  22. Shao B, Xu W, Dai H, Tu P, Li Z, Gao X. A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb. Biochem Biophys Res Commun. 2004;320:1103-11 pubmed
    The immunopotentiating effect of the roots of Astragalus membranaceus, a medicinal herb, has been associated with its polysaccharide fractions (Astragalus polysaccharides, APS)...
  23. Luo Z, Zhong L, Han X, Wang H, Zhong J, Xuan Z. Astragalus membranaceus prevents daunorubicin-induced apoptosis of cultured neonatal cardiomyocytes: role of free radical effect of Astragalus membranaceus on daunorubicin cardiotoxicity. Phytother Res. 2009;23:761-7 pubmed publisher
    ..To determine whether antioxidant agents can reduce the cardiotoxicity of anthracyclines, a herb Astragalus membranaceus was introduced, which has been widely used for the treatment of cardiovascular diseases in China and was ..
  24. Jin H, Luo Q, Zheng Y, Nurahmat M, Wu J, Li B, et al. CD4+CD25+Foxp3+ T cells contribute to the antiasthmatic effects of Astragalus membranaceus extract in a rat model of asthma. Int Immunopharmacol. 2013;15:42-9 pubmed publisher
    b>Astragalus membranaceus (AM), a traditional Chinese medicinal herb, has been widely used for centuries to treat asthma in China...
  25. Zhang L, Liu H, Hsiao P, Kuo L, Lee I, Wu T, et al. New isoflavonoid glycosides and related constituents from astragali radix ( Astragalus membranaceus ) and their inhibitory activity on nitric oxide production. J Agric Food Chem. 2011;59:1131-7 pubmed publisher
    ..including 16 isoflavonoids, 7 astragalasides, and 1 benzoquinone, have been isolated from the roots of Astragalus membranaceus (Astragali radix)...
  26. Kuo Y, Tsai W, Loke S, Wu T, Chiou W. Astragalus membranaceus flavonoids (AMF) ameliorate chronic fatigue syndrome induced by food intake restriction plus forced swimming. J Ethnopharmacol. 2009;122:28-34 pubmed publisher
    Alteration of immune function may be associated with chronic fatigue syndrome (CFS) and this study reveals the immunoregulatory effect of Astragalus membranaceus flavonoids (AMF).
  27. Sun W, Wei W, Gui S, Wu L, Wang H. Protective effect of extract from Paeonia lactiflora and Astragalus membranaceus against liver injury induced by bacillus Calmette-Guérin and lipopolysaccharide in mice. Basic Clin Pharmacol Toxicol. 2008;103:143-9 pubmed publisher
    Paeonia lactiflora and Astragalus membranaceus are two popular traditional Chinese medicines, commonly used in Chinese herb prescription to treat liver disease. The extract from the roots of P. lactiflora and A...
  28. Lee S, Oh S, Seo S, Ahn H, Geum D, Cho J, et al. Oral administration of Astragalus membranaceus inhibits the development of DNFB-induced dermatitis in NC/Nga mice. Biol Pharm Bull. 2007;30:1468-71 pubmed
    ..b>Astragalus membranaceus (AM), is a popular herbal medicine used to treat allergic diseases in East Asia...
  29. Zhang B, Hu S, Qiu L, Zhu J, Xie X, Sun J, et al. Effects of Astragalus membranaceus and its main components on the acute phase endothelial dysfunction induced by homocysteine. Vascul Pharmacol. 2007;46:278-85 pubmed
    This study was designed to investigate the effects of Astragalus membranaceus (AM) and its main components, astragalus saponin (ASP), astragalus polysaccharide (APS) and aminobutyric acid (GABA), on homocysteine (Hcy) induced acute ..
  30. Wu J, Sun W, Hu S, Zhang S, Wei W. A standardized extract from Paeonia lactiflora and Astragalus membranaceus induces apoptosis and inhibits the proliferation, migration and invasion of human hepatoma cell lines. Int J Oncol. 2013;43:1643-51 pubmed publisher
    Paeonia lactiflora and Astragalus membranaceus are two traditional Chinese medicines, which are commonly used in Chinese herb prescription to treat liver diseases...
  31. Chen R, Shao H, Lin S, Zhang J, Xu K. Treatment with Astragalus membranaceus produces antioxidative effects and attenuates intestinal mucosa injury induced by intestinal ischemia-reperfusion in rats. Am J Chin Med. 2011;39:879-87 pubmed publisher
    b>Astragalus membranaceus, also known as huang qi, a traditional Chinese medicine, is often used in formulas for deficiency of vital energy characterized by limb weakness, pale face, and dizziness...
  32. Hong M, Ko E, Park S, Chang M. Inhibitory effect of Astragalus membranaceus root on matrix metalloproteinase-1 collagenase expression and procollagen destruction in ultraviolet B-irradiated human dermal fibroblasts by suppressing nuclear factor kappa-B activity. J Pharm Pharmacol. 2013;65:142-8 pubmed publisher
    The root of Astragalus membranaceus, regarded as a tonic in traditional Korean medicine, has been prescribed for long periods to treat chronic illness by boosting the immune system...
  33. Ma X, Tu P, Chen Y, Zhang T, Wei Y. [Preparative isolation and purification of calycosin and formononetin from Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao by high-speed counter-current chromatography]. Se Pu. 2005;23:299-301 pubmed
    ..HSCCC) was used for the separation of calycosin and formononetin from the ethyl acetate extract of Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao...
  34. Shen P, Liu M, Ng T, Chan Y, Yong E. Differential effects of isoflavones, from Astragalus membranaceus and Pueraria thomsonii, on the activation of PPARalpha, PPARgamma, and adipocyte differentiation in vitro. J Nutr. 2006;136:899-905 pubmed
    ..Extracts of Astragalus membranaceus and Pueraria thomsonii significantly activated PPARalpha and PPARgamma...
  35. Matkovic Z, Zivkovic V, Korica M, Plavec D, Pecanic S, Tudoric N. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res. 2010;24:175-81 pubmed publisher
    The study was designed to investigate efficacy and safety of Astragalus membranaceus (AM) in the treatment of patients with seasonal allergic rhinitis (SAR)...
  36. Song J, Meng L, Li S, Qu L, Li X. A combination of Chinese herbs, Astragalus membranaceus var. mongholicus and Angelica sinensis, improved renal microvascular insufficiency in 5/6 nephrectomized rats. Vascul Pharmacol. 2009;50:185-93 pubmed publisher
    ..The renoprotective effects may be associated with reduction of proteinuria, up-regulation of VEGF which may reduce the loss of capillaries and improve microstructure dysfunction...
  37. Gan X, Hei Z, Huang H, Chen L, Li S, Cai J. Effect of Astragalus membranaceus injection on the activity of the intestinal mucosal mast cells after hemorrhagic shock-reperfusion in rats. Chin Med J (Engl). 2006;119:1892-8 pubmed
    ..b>Astragalus membranaceus can protect intestinal mucosa against intestinal oxidative damage after hemorrhagic shock, and some ..
  38. Kim W, Kim S, Park S, Chang M. Astragalus membranaceus ameliorates reproductive toxicity induced by cyclophosphamide in male mice. Phytother Res. 2012;26:1418-21 pubmed publisher
    The root of Astragalus membranaceus B(UNGE) (AM) is a medicinal herb that has been capable of reducing the adverse effects of conventional chemotherapy...
  39. Ionkova I, Momekov G, Proksch P. Effects of cycloartane saponins from hairy roots of Astragalus membranaceus Bge., on human tumor cell targets. Fitoterapia. 2010;81:447-51 pubmed publisher
    For the first time three different natural compounds, isolated from hairy roots of Astragalus membranaceus, cultivated in airlift bioreactor were tested for their cytotoxic potential and apoptosis induction in a panel of human tumor cell ..
  40. Lee K, Jeon Y. Macrophage activation by polysaccharide isolated from Astragalus membranaceus. Int Immunopharmacol. 2005;5:1225-33 pubmed
    We show that APS, a polysaccharide isolated from the roots of Astragalus membranaceus, significantly induces nitric oxide (NO) production and inducible NO synthase (iNOS) transcription through the activation of nuclear factor-kappaB/Rel (..
  41. Wu F, Chen X. [A review of pharmacological study on Astragalus membranaceus (Fisch.) Bge]. Zhong Yao Cai. 2004;27:232-4 pubmed
  42. Yang X, Huang S, Chen J, Song N, Wang L, Zhang Z, et al. Evaluation of the adjuvant properties of Astragalus membranaceus and Scutellaria baicalensis GEORGI in the immune protection induced by UV-attenuated Toxoplasma gondii in mouse models. Vaccine. 2010;28:737-43 pubmed publisher
    ..To investigate the possible adjuvant effect of aqueous extracts obtained from medicinal herbs of Astragalus membranaceus (Am) and Scutellaria baicalensis GEORGI (Sb) on the immune response to Toxoplasma gondii in the mouse ..
  43. Zwickey H, Brush J, Iacullo C, Connelly E, Gregory W, Soumyanath A, et al. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD25 expression in humans: a pilot study. Phytother Res. 2007;21:1109-12 pubmed
    ..examined CD25 expression on T cells after ingestion of three commonly used herbs: Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra, administered singly and in combination...
  44. Cho W, Leung K. In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus. J Ethnopharmacol. 2007;113:132-41 pubmed
    b>Astragalus membranaceus is a common traditional Chinese medicinal plant widely used as a tonic to enhance the body's natural defense mechanisms. In this study, bioactive fractions were isolated from the roots of Astragalus membranaceus...
  45. Li M, Wang W, Xue J, Gu Y, Lin S. Meta-analysis of the clinical value of Astragalus membranaceus in diabetic nephropathy. J Ethnopharmacol. 2011;133:412-9 pubmed publisher
    Nowadays diabetic nephropathy (DN) has become a serious problem. Astragalus membranaceus is a traditional herb used for thousands of years in China and East Asia for kidney disease...
  46. Dong J, Gu H, Ma C, Zhang F, Chen Z, Zhang Y. [Effects of large dose of Astragalus membranaceus on the dendritic cell induction of peripheral mononuclear cell and antigen presenting ability of dendritic cells in children with acute leukemia]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2005;25:872-5 pubmed
    To explore the effects of large dose of Astragalus membranaceus (Astragalus) on the dentritic cell (DC) induction in vitro and augumentation by peripheral mononuclear cell (MNC) and on antigen presenting ability of DC in children with ..
  47. Lei Y, Wang J, Chen K. [Comparative study on angiogenesis effect of Astragalus membranaceus and Angelica sinensis in chick embryo choriollantoic membrane]. Zhongguo Zhong Yao Za Zhi. 2003;28:876-8 pubmed
    To explore the angiogenesis effect of Astragalus membranaceus and Angelica sinensis with different ratio in chick embryo chorioallantoic membrane (CAM).
  48. Han Q, Song J, Qiao C, Wong L, Xu H. Preparative isolation of cyclolanostane-type saponins from Astragalus membranaceus bge. var. mongholicus (Bge.) Hsiao by TLC-MS/MS guided high-speed counter-current chromatography. J Sep Sci. 2007;30:135-40 pubmed
    ..astragalosides I and II, were first identified by TLC-MS/MS in the ethyl acetate extract of the roots of Astragalus membranaceus Bge var. mongholicus (Bge.) Hsiao without chemical reference substances...
  49. Gao X, Xu X, Pan R, Li Y, Luo Y, Xia Y, et al. Saponin fraction from Astragalus membranaceus roots protects mice against polymicrobial sepsis induced by cecal ligation and puncture by inhibiting inflammation and upregulating protein C pathway. J Nat Med. 2009;63:421-9 pubmed publisher
    ..Based on the beneficial effects of the saponin fraction from Astragalus membranaceus roots (SAM) against inflammation, liver dysfunction, and endothelium injury, we investigated the ..
  50. Han D, Lee H, Hahm D. Wound-healing activity of Astragali Radix in rats. Methods Find Exp Clin Pharmacol. 2009;31:95-100 pubmed publisher
    ..To evaluate the wound-healing effects of Astragali Radix (AR) (the root of Astragalus membranaceus [Fisch.]), experimental open wounds were made on the dorsal side of rats under anesthesia...
  51. Yang Z, Sun H, Fang W. Haemolytic activities and adjuvant effect of Astragalus membranaceus saponins (AMS) on the immune responses to ovalbumin in mice. Vaccine. 2005;23:5196-203 pubmed
    In this study, the haemolytic activities of Astragalus membranaceus saponins (AMS) and its adjuvant potentials on the cellular and humoral immune responses of ICR mice against OVA were evaluated...
  52. Kim J, Kim M, Yang G, Huh Y, Kim S, Yang W. Effects of topical application of Astragalus membranaceus on allergic dermatitis. Immunopharmacol Immunotoxicol. 2013;35:151-6 pubmed publisher
    b>Astragalus membranaceus (AM) is one of the most popular health-promoting herbs in East Asia, and has been used in traditional medicine for more than 2000 years...
  53. Dong T, Zhao K, Gao Q, Ji Z, Zhu T, Li J, et al. Chemical and biological assessment of a chinese herbal decoction containing Radix Astragali and Radix Angelicae Sinensis: Determination of drug ratio in having optimized properties. J Agric Food Chem. 2006;54:2767-74 pubmed
    ..The current results support the ancient formulation of DBT, and the identified chemicals could serve as markers for quality control of DBT...