dioscorea

Summary

Summary: A plant genus best known for edible underground tubers. Yam may also refer to a moist variety of sweet potato, IPOMOEA BATATAS.

Top Publications

  1. Tewtrakul S, Itharat A. Anti-allergic substances from the rhizomes of Dioscorea membranacea. Bioorg Med Chem. 2006;14:8707-11 pubmed
    ..Of the five species studied, the ethanolic extract of Dioscorea membranacea exhibited potent inhibitory activity against beta-hexosaminidase release as a marker of ..
  2. Yin J, Tezuka Y, Kouda K, Le Tran Q, Miyahara T, Chen Y, et al. In vivo antiosteoporotic activity of a fraction of Dioscorea spongiosa and its constituent, 22-O-methylprotodioscin. Planta Med. 2004;70:220-6 pubmed
    The antiosteoporotic activity of the 90 % EtOH fraction of the water extract of rhizomes of Dioscorea spongiosa and methylprotodioscin, its major constituent, were examined in the model of postmenopausal bone loss using ovariectomized (..
  3. Akissoe N, Mestres C, Hounhouigan J, Nago M. Biochemical origin of browning during the processing of fresh Yam (Dioscorea spp.) into dried product. J Agric Food Chem. 2005;53:2552-7 pubmed
    ..PPO activity was 50% higher in nonprocessed freeze-dried Florido (Dioscorea alata) than in nonprocessed freeze-dried Deba (Dioscorea rotundata). It decreased progressively during blanching...
  4. Ghosh S, Patil S, Ahire M, Kitture R, Kale S, Pardesi K, et al. Synthesis of silver nanoparticles using Dioscorea bulbifera tuber extract and evaluation of its synergistic potential in combination with antimicrobial agents. Int J Nanomedicine. 2012;7:483-96 pubmed publisher
    ..Among the 600 species of the genus Dioscorea, Dioscorea bulbifera has profound therapeutic applications due to its unique phytochemistry...
  5. Li P, Mou Y, Shan T, Xu J, Li Y, Lu S, et al. Effects of polysaccharide elicitors from endophytic Fusarium oxysporium Dzf17 on growth and diosgenin production in cell suspension culture of Dioscorea zingiberensis. Molecules. 2011;16:9003-16 pubmed publisher
    ..SPS), were prepared from the endophytic fungus Fusarium oxysporium Dzf17 isolated from the rhizomes of Dioscorea zingiberensis...
  6. Wang J, Ji L, Liu H, Wang Z. Study of the hepatotoxicity induced by Dioscorea bulbifera L. rhizome in mice. Biosci Trends. 2010;4:79-85 pubmed
    b>Dioscorea bulbifera L. is a medicinal plant. The present study was undertaken to investigate the hepatotoxicity induced by D. bulbifera in mice...
  7. Hsu W, Lee B, Pan T. Red mold dioscorea-induced G2/M arrest and apoptosis in human oral cancer cells. J Sci Food Agric. 2010;90:2709-15 pubmed publisher
    Monascus-fermented products are among the most commonly used traditional food supplements. Dioscorea is known to exhibit anticancer properties...
  8. Scarcelli N, Tostain S, Vigouroux Y, Agbangla C, Dainou O, Pham J. Farmers' use of wild relative and sexual reproduction in a vegetatively propagated crop. The case of yam in Benin. Mol Ecol. 2006;15:2421-31 pubmed
    ..of ennoblement of spontaneous yams, an original traditional farmers' practice, on the genetic diversity of yam (Dioscorea sp.) in Benin...
  9. Xu L, Zhou L, Zhao J, Li J, Li X, Wang J. Fungal endophytes from Dioscorea zingiberensis rhizomes and their antibacterial activity. Lett Appl Microbiol. 2008;46:68-72 pubmed
    ..to isolate and characterize the endophytic fungi from the rhizomes of the Chinese traditional medicinal plant Dioscorea zingiberensis and to detect their antibacterial activities...

More Information

Publications80

  1. Wang T, Choi R, Li J, Bi C, Ran W, Chen X, et al. Trillin, a steroidal saponin isolated from the rhizomes of Dioscorea nipponica, exerts protective effects against hyperlipidemia and oxidative stress. J Ethnopharmacol. 2012;139:214-20 pubmed publisher
    ..The rhizome of Dioscorea nipponica (Dioscoreae Nipponicae Rhizoma) is a traditional Chinese herb being prescribed to improve the blood ..
  2. Lee C, Wang J, Kuo S, Pan T. Monascus fermentation of dioscorea for increasing the production of cholesterol-lowering agent--monacolin K and antiinflammation agent--monascin. Appl Microbiol Biotechnol. 2006;72:1254-62 pubmed
    ..This research uses sweet potato (Ipomoea batatas), potato (Solanum tuberosum), casava (Manihot esculenta), and dioscorea (Dioscorea batatas) as the substrates and discusses the best substrate to produce monacolin K...
  3. Kuete V, Betrandteponno R, Mbaveng A, Tapondjou L, Meyer J, Barboni L, et al. Antibacterial activities of the extracts, fractions and compounds from Dioscorea bulbifera. BMC Complement Altern Med. 2012;12:228 pubmed publisher
    b>Dioscorea bulbifera is an African medicinal plant used to treat microbial infections. In the present study, the methanol extract, fractions (DBB1 and DBB2) and six compounds isolated from the bulbils of D...
  4. Panneerselvam R, Abdul Jaleel C, Somasundaram R, Sridharan R, Gomathinayagam M. Carbohydrate metabolism in Dioscorea esculenta (Lour.) Burk. tubers and Curcuma longa L. rhizomes during two phases of dormancy. Colloids Surf B Biointerfaces. 2007;59:59-66 pubmed
    We have examined the changes in carbohydrate metabolism in food yam (Dioscorea esculenta (Lour.) Burk.) tubers and in an economically important spice cum medicinal plant turmeric (Curcuma longa L.) rhizomes under storage...
  5. Jin M, Lu Y, Yang J, Jo T, Park Y, Lee C, et al. Anti-inflammatory activity of 6-hydroxy-2,7-dimethoxy-1,4-henanthraquinone from tuberous roots of yam (Dioscorea batatas) through inhibition of prostaglandin D? and leukotriene C? production in mouse bone marrow-derived mast cells. Arch Pharm Res. 2011;34:1495-501 pubmed publisher
    6-Hydroxy-2,7-dimethoxy-1,4-phenanthraquinone (PAQ) isolated from the tuberous roots of Yam (Dioscorea batatas) inhibited cyclooxygenase-2 (COX-2) and cyclooxygenase-1 (COX-1) dependent prostaglandin D(2) (PGD(2)) generation in mouse ..
  6. Li Y, Li P, Mou Y, Zhao J, Shan T, Ding C, et al. Enhancement of diepoxin ? production in liquid culture of endophytic fungus Berkleasmium sp. Dzf12 by polysaccharides from its host plant Dioscorea zingiberensis. World J Microbiol Biotechnol. 2012;28:1407-13 pubmed publisher
    ..Dzf12 by the polysaccharides from its host plant Dioscorea zingiberensis which serve as elicitors...
  7. Hou W, Hsu F, Lee M. Yam (Dioscorea batatas) tuber mucilage exhibited antioxidant activities in vitro. Planta Med. 2002;68:1072-6 pubmed
    The yam (Dioscorea batatas Decne) tuber mucilage (YTM) was extracted and partially purified by SDS and heating treatments...
  8. Ohizumi Y, Gaidamashvili M, Ohwada S, Matsuda K, Kominami J, Nakamura Tsuruta S, et al. Mannose-binding lectin from yam (Dioscorea batatas) tubers with insecticidal properties against Helicoverpa armigera (Lepidoptera: Noctuidae). J Agric Food Chem. 2009;57:2896-902 pubmed publisher
    The amino acid sequence of mannose-binding lectin, named DB1, from the yam (Dioscorea batatas, synonym Dioscorea polystachya) tubers was determined...
  9. Hou W, Lee M, Chen H, Liang W, Han C, Liu Y, et al. Antioxidant activities of dioscorin, the storage protein of yam (Dioscorea batatas Decne) tuber. J Agric Food Chem. 2001;49:4956-60 pubmed
    Dioscorin, the storage protein of yam (Dioscorea batatas Decne) tuber (which is different from dioscorine found in tubers of Dioscorea hirsuta), was purified to homogeneity after DE-52 ion exchange column according to the methods of Hou ..
  10. Hansen D, Dastidar S, Cai Z, Penaflor C, Kuehl J, Boore J, et al. Phylogenetic and evolutionary implications of complete chloroplast genome sequences of four early-diverging angiosperms: Buxus (Buxaceae), Chloranthus (Chloranthaceae), Dioscorea (Dioscoreaceae), and Illicium (Schisandraceae). Mol Phylogenet Evol. 2007;45:547-63 pubmed
    ..sequences of four early-diverging lineages of angiosperms, Buxus (Buxaceae), Chloranthus (Chloranthaceae), Dioscorea (Dioscoreaceae), and Illicium (Schisandraceae), to examine the organization and evolution of plastid genomes and ..
  11. Wu W, Liu L, Chung C, Jou H, Wang T. Estrogenic effect of yam ingestion in healthy postmenopausal women. J Am Coll Nutr. 2005;24:235-43 pubmed
    Yam (Dioscorea) has been used to treat menopausal symptom folklorically. This study was to investigate the effects of yam ingestion on lipids, antioxidant status, and sex hormones in postmenopausal women...
  12. Tang Y, Yi T, Chen H, Zhao Z, Liang Z, Chen H. Quantitative comparison of multiple components in Dioscorea nipponica and D. panthaica by ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. Phytochem Anal. 2013;24:413-22 pubmed publisher
    b>Dioscorea nipponica (DN) and D. panthaica (DP) have been uniquely prepared as herbal medicinal products for treating coronary heart disease (CHD) in China...
  13. Li Y, Shan T, Mou Y, Li P, Zhao J, Zhao W, et al. Enhancement of palmarumycin C12 and C13 production in liquid culture of the endophytic fungus Berkleasmium sp. Dzf12 by oligosaccharides from its host plant Dioscorea zingiberensis. Molecules. 2012;17:3761-73 pubmed publisher
    ..sodium hydroxide-extracted polysaccharide (SEP) and acid-extracted polysaccharide (AEP) from the rhizomes of Dioscorea zingiberensis...
  14. McAnuff M, Omoruyi F, Sotelo López A, Asemota H. Proximate analysis and some antinutritional factor constituents in selected varieties of Jamaican yams (Dioscorea and Rajana spp.). Plant Foods Hum Nutr. 2005;60:93-8 pubmed
    Two wild (Dioscorea polygonoides and Rajana cordata) and seven cultivated varieties of Jamaican yams (Dioscorea spp.) were analyzed for their proximate composition and the levels of antinutritional factors. The protein level range was 47...
  15. Wu C, Lee C, Pan T. Red mold dioscorea has a greater antihypertensive effect than traditional red mold rice in spontaneously hypertensive rats. J Agric Food Chem. 2009;57:5035-41 pubmed publisher
    The aim of this study is to investigate the antihypertensive effects of red mold rice (RMR) and red mold dioscorea (RMD) by low-dose oral administration to spontaneously hypertensive rats (SHRs)...
  16. Lee C, Hung H, Wang J, Pan T. Improving the ratio of monacolin K to citrinin production of Monascus purpureus NTU 568 under dioscorea medium through the mediation of pH value and ethanol addition. J Agric Food Chem. 2007;55:6493-502 pubmed
    Using dioscorea root as substrate of Monascus species was found to stimulate monacolin K (cholesterol-lowering agent) formation in our previous study, but the mycotoxin-citrinin has never been studied...
  17. Shi Y, Yu C, Liao V, Pan T. Monascus-fermented dioscorea enhances oxidative stress resistance via DAF-16/FOXO in Caenorhabditis elegans. PLoS ONE. 2012;7:e39515 pubmed publisher
    ..To evaluate whether Monascus-fermented dioscorea products have potential as nutritional supplements, Monascus-fermented dioscorea's modulation of oxidative-..
  18. Shriram V, Jahagirdar S, Latha C, Kumar V, Puranik V, Rojatkar S, et al. A potential plasmid-curing agent, 8-epidiosbulbin E acetate, from Dioscorea bulbifera L. against multidrug-resistant bacteria. Int J Antimicrob Agents. 2008;32:405-10 pubmed publisher
    Bioassay-guided fractionation of an aqueous methanolic extract of Dioscorea bulbifera L. bulbs was performed using organic solvents...
  19. Kwon C, Sohn H, Kim S, Kim J, Son K, Lee J, et al. Anti-obesity effect of Dioscorea nipponica Makino with lipase-inhibitory activity in rodents. Biosci Biotechnol Biochem. 2003;67:1451-6 pubmed
    ..for pancreatic lipase inhibitors, which could be used as an anti-obesity measure, the methanol extract of Dioscorea nipponica Makino powder (DP) appeared to have potent inhibitory activity against porcine pancreatic lipase with ..
  20. Chen G, Wei W, Xu S. Effect and mechanism of total saponin of Dioscorea on animal experimental hyperuricemia. Am J Chin Med. 2006;34:77-85 pubmed
    In this study, we investigated the effects and mechanisms of Total Saponin of Dioscorea (TSD) on animal experimental hyperuricemia...
  21. Nagai T, Nagashima T. Functional properties of dioscorin, a soluble viscous protein from Japanese yam (Dioscorea opposita thunb.) tuber mucilage Tororo. Z Naturforsch C. 2006;61:792-8 pubmed
    A soluble viscous protein was purified from yam (Dioscorea opposita Thunb.) tuber mucilage tororo by chromatographic steps, and its functional properties were estimated...
  22. Jin M, Suh S, Yang J, Lu Y, Kim S, Kwon S, et al. Anti-inflammatory activity of bark of Dioscorea batatas DECNE through the inhibition of iNOS and COX-2 expressions in RAW264.7 cells via NF-?B and ERK1/2 inactivation. Food Chem Toxicol. 2010;48:3073-9 pubmed publisher
    ..a bioactive herbal medicine with anti-inflammatory activity from an ethanol extract derived from the bark of Dioscorea batatas DECNE (BDB) in RAW264.7 cells...
  23. Wang T, Choi R, Li J, Bi C, Zang L, Liu Z, et al. Antihyperlipidemic effect of protodioscin, an active ingredient isolated from the rhizomes of Dioscorea nipponica. Planta Med. 2010;76:1642-6 pubmed publisher
    ..Here, a bioactive phytochemical, protodioscin, isolated from the rhizomes of Dioscorea nipponica (Rhizoma Dioscoreae Nipponicae), was identified for its anti-hyperlipidemic effect...
  24. Chang S, Lee Y, Liu S, Chang T. Chinese yam (Dioscorea alata cv. Tainung No. 2) feeding exhibited antioxidative effects in hyperhomocysteinemia rats. J Agric Food Chem. 2004;52:1720-5 pubmed
    Antioxidative effects of Dioscorea alata (D. alata) were investigated in hyperhomocysteinemia (HHcy) induced by methionine (Met) oral feeding (1 (g/kg of BW)/day)...
  25. Swain M, Naskar S, Ray R. Indole-3-acetic acid production and effect on sprouting of yam (Dioscorea rotundata L.) minisetts by Bacillus subtilis isolated from culturable cowdung microflora. Pol J Microbiol. 2007;56:103-10 pubmed
    ..subtilis type strain MTCC 441. Application of B. subtilis suspension (8 x 10(9) CFU/ml) on the surface of yam (Dioscorea rotundata L...
  26. Tong Q, He Y, Zhao Q, Qing Y, Huang W, Wu X. Cytotoxicity and apoptosis-inducing effect of steroidal saponins from Dioscorea zingiberensis Wright against cancer cells. Steroids. 2012;77:1219-27 pubmed publisher
    Steroidal saponins from Dioscorea zingiberensis Wright (DZW) have shown cytotoxic activity in cancer cells...
  27. Lee C, Kung Y, Wang J, Lung T, Pan T. Enhanced hypolipidemic effect and safety of red mold dioscorea cultured in deep ocean water. J Agric Food Chem. 2011;59:8199-207 pubmed publisher
    Red mold dioscorea (RMD) produced by Monascus sp. was proven to be a hypolipidemic functional food...
  28. Gnonlonfin G, Hell K, Siame A, Fandohan P. Infestation and population dynamics of insects on stored cassava and yams chips in Benin, West Africa. J Econ Entomol. 2008;101:1967-73 pubmed
    Natural insect infestation in cassava (Manihot esculenta Crantz subspecies esculenta) and yam (Dioscorea spp...
  29. Niu C, Chen W, Wu H, Cheng K, Wen Y, Lin K, et al. Decrease of plasma glucose by allantoin, an active principle of yam ( Dioscorea spp.), in streptozotocin-induced diabetic rats. J Agric Food Chem. 2010;58:12031-5 pubmed publisher
    ..This study suggests that allantoin increases GLUT4 gene expression in muscle by increasing ?-endorphin secretion from the adrenal gland in STZ-diabetic rats...
  30. Yin J, Kouda K, Tezuka Y, Tran Q, Miyahara T, Chen Y, et al. Steroidal glycosides from the rhizomes of Dioscorea spongiosa. J Nat Prod. 2003;66:646-50 pubmed
    A water extract of the rhizomes of Dioscorea spongiosa, which showed antiosteoporotic activity, was examined, and four new pregnane glycosides, named spongipregnolosides A-D (1-4), and two new cholestane glycosides, named spongiosides A (..
  31. Shujun W, Jinglin Y, Wenyuan G, Hongyan L, Peigen X. New starches from traditional Chinese medicine (TCM)--Chinese yam (Dioscorea opposita Thunb.) cultivars. Carbohydr Res. 2006;341:289-93 pubmed
    The starches separated from two different Dioscorea opposita Thunb. cultivars were investigated for morphological, thermal and crystal properties. The shape of starch granules separated from different D. opposita Thunb...
  32. Chiu C, Deng J, Chang H, Chen Y, Lee M, Hou W, et al. Antioxidant and anti-inflammatory properties of Taiwanese yam (Dioscorea japonica Thunb. var. pseudojaponica (Hayata) Yamam.) and its reference compounds. Food Chem. 2013;141:1087-96 pubmed publisher
    b>Dioscorea japonica Thunb. var. pseudojaponica (DP) is consumed as food and widely used in traditional Chinese medicine in Taiwan...
  33. Kim S, Jwa H, Yanagawa Y, Park T. Extract from Dioscorea batatas ameliorates insulin resistance in mice fed a high-fat diet. J Med Food. 2012;15:527-34 pubmed publisher
    The aim of this study was to investigate whether Dioscorea batatas (DB) extract attenuates high-fat diet (HFD)-induced insulin resistance in the visceral adipose tissues of mice, and by what mechanism(s)...
  34. Son I, Kim J, Sohn H, Son K, Kim J, Kwon C. Antioxidative and hypolipidemic effects of diosgenin, a steroidal saponin of yam (Dioscorea spp.), on high-cholesterol fed rats. Biosci Biotechnol Biochem. 2007;71:3063-71 pubmed
    ..5% diosgenin group. These results suggest that diosgenin could be a very useful compound to control hypercholesterolemia by both improving the lipid profile and modulating oxidative stress...
  35. Ali Z, Smillie T, Khan I. Two spirostan steroid glycoside fatty esters from Dioscorea cayenensis. Nat Prod Commun. 2013;8:323-6 pubmed
    ..esters, progenin III palmitate (1) and progenin III linoleate (2), were isolated from the MeOH extract of Dioscorea cayenensis rhizomes...
  36. Bhandari M, Kawabata J. Bitterness and toxicity in wild yam (Dioscorea spp.) tubers of Nepal. Plant Foods Hum Nutr. 2005;60:129-35 pubmed
    ..Domestic cooking methods were found to be very efficient in removing bitterness, thus making the bitter yams palatable...
  37. Arnau G, Nemorin A, Maledon E, Abraham K. Revision of ploidy status of Dioscorea alata L. (Dioscoreaceae) by cytogenetic and microsatellite segregation analysis. Theor Appl Genet. 2009;118:1239-49 pubmed publisher
    b>Dioscorea alata is a polyploid species with several ploidy levels and its basic chromosome number has been considered by most authors to be x = 10...
  38. Tchabi A, Burger S, Coyne D, Hountondji F, Lawouin L, Wiemken A, et al. Promiscuous arbuscular mycorrhizal symbiosis of yam (Dioscorea spp.), a key staple crop in West Africa. Mycorrhiza. 2009;19:375-392 pubmed publisher
    Yam (Dioscorea spp.) is a tuberous staple food crop of major importance in the sub-Saharan savannas of West Africa. Optimal yields commonly are obtained only in the first year following slash-and-burn in the shifting cultivation systems...
  39. Liu Y, Shang H, Wang C, Hsu F, Hou W. Immunomodulatory activity of dioscorin, the storage protein of yam (Dioscorea alata cv. Tainong No. 1) tuber. Food Chem Toxicol. 2007;45:2312-8 pubmed
    The purified dioscorin from yam (Dioscorea alata L. cv. Tainong 1) tuber was previously reported (Hsu et al., 2002. J. Agric. Food Chem., 50, 6109-6113)...
  40. Fu S, Hsu Y, Lee P, Hou W, Hung L, Lin C, et al. Dioscorin isolated from Dioscorea alata activates TLR4-signaling pathways and induces cytokine expression in macrophages. Biochem Biophys Res Commun. 2006;339:137-44 pubmed
    ..One of the plant components we identified from the screening was dioscorin, the glycoprotein isolated from Dioscorea alata...
  41. Oh P, Lim K. Glycoprotein isolated from Dioscorea batatas Decne modulates expressions of IL-4 and IL-10 in primary-cultured mouse lymphocytes. Cell Biochem Funct. 2009;27:316-22 pubmed publisher
    In the present study, we investigated the anti-allergic activity of a glycoprotein isolated from Dioscorea batatas Decne (DBD glycoprotein, 30 kDa) on ovalbumin (OVA, 100 microg ml(-1))-induced T helper (Th) type-2 response in primary ..
  42. Li R, Zhou Y, Wu Z, Ding L. ESI-QqTOF-MS/MS and APCI-IT-MS/MS analysis of steroid saponins from the rhizomes of Dioscorea panthaica. J Mass Spectrom. 2006;41:1-22 pubmed
    ..source (ESI-QqTOF-MS), accurate molecular weights of 13 steroid saponins extracted from the rhizomes of Dioscorea panthaica were acquired and the corresponding molecular formulae obtained...
  43. Zhao J, Zheng B, Li Y, Shan T, Mou Y, Lu S, et al. Enhancement of diepoxin ? production by yeast extract and its fractions in liquid culture of Berkleasmium-like endophytic fungus Dzf12 from Dioscorea zingiberensis. Molecules. 2011;16:847-56 pubmed publisher
    ..a diversity of bioactivities) production in liquid culture of Berkleasmium-like endophytic fungus Dzf12 from Dioscorea zingiberensis...
  44. Wang W, Li P, Wang X, Jing W, Chen L, Liu A. Quantification of saponins in Dioscorea panthaica Prain et Burk rhizomes with monolithic column using rapid resolution liquid chromatography coupled with a triple quadruple electrospray tandem mass spectrometry. J Pharm Biomed Anal. 2012;71:152-6 pubmed publisher
    ..tandem mass spectrometric method was established to identify and quantify steroid saponins in the rhizomes of Dioscorea panthaica Prain et Burk, a traditional Chinese medicine...
  45. Gaidamashvili M, Ohizumi Y, Iijima S, Takayama T, Ogawa T, Muramoto K. Characterization of the yam tuber storage proteins from Dioscorea batatas exhibiting unique lectin activities. J Biol Chem. 2004;279:26028-35 pubmed
    Four major proteins designated DB1, DB2, DB3, and DB4 were isolated and characterized from the yam tuber Dioscorea batatas. The ratios of their yields were 20:50:20:10...
  46. Hsu J, Wu Y, Liu I, Cheng J. Dioscorea as the principal herb of Die-Huang-Wan, a widely used herbal mixture in China, for improvement of insulin resistance in fructose-rich chow-fed rats. J Ethnopharmacol. 2007;112:577-84 pubmed
    ..received an oral administration of Die-Huang-Wan at 26 mg/kg for 60 min but it disappeared with the deletion of dioscorea (Dioscoreae rhizoma) while this action was not modified by the deletion of other five herbs...
  47. Teponno R, Tapondjou A, Gatsing D, Djoukeng J, Abou Mansour E, Tabacchi R, et al. Bafoudiosbulbins A, and B, two anti-salmonellal clerodane diterpenoids from Dioscorea bulbifera L. var sativa. Phytochemistry. 2006;67:1957-63 pubmed
    ..beta-sitosterol and 3-O-beta-D-glucopyranosyl-beta-sitosterol were isolated from the tubers of Dioscorea bulbifera L. var sativa...
  48. Gao X, Li B, Jiang H, Liu F, Xu D, Liu Z. Dioscorea opposita reverses dexamethasone induced insulin resistance. Fitoterapia. 2007;78:12-5 pubmed
    The effects of Dioscorea opposita (huai shan yao, HSY) on dexamethasone-induced insulin resistance were investigated in vitro and in vivo. D...
  49. Ma C, Wang W, Chen Y, Liu R, Wang R, Du L. Neuroprotective and antioxidant activity of compounds from the aerial parts of Dioscorea opposita. J Nat Prod. 2005;68:1259-61 pubmed
    Bioactivity-guided fractionation of an ethanol extract of the aerial parts of Dioscorea opposita afforded a new compound, 6,7-dihydroxy-2-methoxy-1,4-phenanthrenedione (1), and four known compounds, chrysoeriol 4'-O-beta-D-..
  50. Ma H, Zhao Z, Wang L, Wang Y, Zhou Q, Wang B. [Comparative study on anti-hypercholesterolemia activity of diosgenin and total saponin of Dioscorea panthaica]. Zhongguo Zhong Yao Za Zhi. 2002;27:528-31 pubmed
    To compare the anti-hypercholesterolemic and cholesterol absorption inhibitory activities between total saponin of Dioscorea panthaica (TSDP) and diosgenin (Dio).
  51. Choi E, Koo S, Hwang J. Immune cell stimulating activity of mucopolysaccharide isolated from yam (Dioscorea batatas). J Ethnopharmacol. 2004;91:1-6 pubmed
    Mucopolysaccharide (YMP) of yam (Dioscorea batatas Decne) was tested for immunomodulatory activity in vitro. We examined the effect of YMP on the viability, cell-mediated cytotoxicity and IFN-gamma secretion of splenic lymphocytes...
  52. Shewry P. Tuber storage proteins. Ann Bot. 2003;91:755-69 pubmed
    ..These are potato (Solanum tuberosum), cassava (Manihot esculenta), sweet potato (Ipomoea batatus), yams (Dioscorea spp.) and taro (Colocasia, Cyrtosperma and Xanthosoma spp.)...
  53. Kang T, Moon E, Hong B, Choi S, Son M, Park J, et al. Diosgenin from Dioscorea nipponica ameliorates diabetic neuropathy by inducing nerve growth factor. Biol Pharm Bull. 2011;34:1493-8 pubmed
    ..We found that DG, the primary spirostane-type steroid in several Dioscorea species, increased NGF levels in the sciatic nerve of diabetic rats...
  54. Liu H, Chou G, Wu T, Guo Y, Wang S, Wang C, et al. Steroidal sapogenins and glycosides from the rhizomes of Dioscorea bulbifera. J Nat Prod. 2009;72:1964-8 pubmed publisher
    ..one new cholestane glycoside, diosbulbiside C (7), and the known compounds 8-10 were isolated from rhizomes of Dioscorea bulbifera. Their structures were elucidated by 1D and 2D NMR techniques, HRFTMS, and chemical methods...
  55. Tewtrakul S, Itharat A. Nitric oxide inhibitory substances from the rhizomes of Dioscorea membranacea. J Ethnopharmacol. 2007;109:412-6 pubmed
    ..7 cell lines. Among the plant species studied, an ethanolic extract of Dioscorea membranacea exhibited the most potent inhibitory activity, with an IC(50) value of 23.6 microg/ml...
  56. Li H, Huang W, Wen Y, Gong G, Zhao Q, Yu G. Anti-thrombotic activity and chemical characterization of steroidal saponins from Dioscorea zingiberensis C.H. Wright. Fitoterapia. 2010;81:1147-56 pubmed publisher
    ..Total steroidal saponins (TSS) extracted from the rhizomes of Dioscorea zingiberensis C.H. Wright (DZW) constitute an effective treatment for cardiovascular disease...
  57. Gong G, Qin Y, Huang W. Anti-thrombosis effect of diosgenin extract from Dioscorea zingiberensis C.H. Wright in vitro and in vivo. Phytomedicine. 2011;18:458-63 pubmed publisher
    ..Extract of Dioscorea zingiberensis C.H. Wright (D...
  58. Li H, Ni J. Treatment of wastewater from Dioscorea zingiberensis tubers used for producing steroid hormones in a microbial fuel cell. Bioresour Technol. 2011;102:2731-5 pubmed publisher
    A two-chamber microbial fuel cell (MFC) was used to treat Dioscorea zingiberensis processing wastewater and generate electricity...
  59. Kim N, Kim S, Kim Y, Kim J, Nam M, Rhim H, et al. Neurotrophic activity of DA-9801, a mixture extract of Dioscorea japonica Thunb. and Dioscorea nipponica Makino, in vitro. J Ethnopharmacol. 2011;137:312-9 pubmed publisher
    b>Dioscorea japonica Thunb. has been traditionally used to treat polyuria and diabetes in Korea.
  60. Qin Y, Wu X, Huang W, Gong G, Li D, He Y, et al. Acute toxicity and sub-chronic toxicity of steroidal saponins from Dioscorea zingiberensis C.H.Wright in rodents. J Ethnopharmacol. 2009;126:543-50 pubmed publisher
    Steroidal saponins from Dioscorea zingiberensis are widely used in China for curing cardiovascular diseases. However, there was little toxicological information available on them.
  61. Wang G, Liu J, Lin B, Wang G, Liu J. Two new furanoid norditerpenes from Dioscorea bulbifera. Chem Pharm Bull (Tokyo). 2009;57:625-7 pubmed
    Two new furanoid norditerpenes (1, 2) were isolated from the root tubers of Dioscorea bulbifera L. Their structures were established on the basis of extensive spectroscopic analysis.
  62. Riley C, Bahado Singh P, Wheatley A, Ahmad M, Asemota H. Relationship between the physicochemical properties of starches and the glycemic indices of some Jamaican yams (Dioscorea spp.). Mol Nutr Food Res. 2008;52:1372-6 pubmed publisher
    ..Differences in the crystalline pattern of the different starches were observed, where RY, LY, and WY displayed the type B crystalline pattern while CY had the intermediate crystallite (type C)...
  63. Hur G, Park H, Kim H, Ye Y, Park H. Identification of Dioscorea batatas (sanyak) allergen as an inhalant and oral allergen. J Korean Med Sci. 2008;23:72-6 pubmed publisher
    b>Dioscorea batatas is widely used in Asia as a herbal medicine or food product with potential health benefits. There have been several reports of occupational asthma caused by inhalation of D. batatas dust...
  64. Lee C, Hung H, Wang J, Pan T. Red mold dioscorea has greater hypolipidemic and antiatherosclerotic effect than traditional red mold rice and unfermented dioscorea in hamsters. J Agric Food Chem. 2007;55:7162-9 pubmed
    Monascus-fermented red mold dioscorea (RMD) was proven to produce higher monacolin K levels than red mold rice (RMR) in our previous study...
  65. Jeon J, Lee J, Lee C, Kim J, Kim S, Nam D. Effect of ethanol extract of dried Chinese yam (Dioscorea batatas) flour containing dioscin on gastrointestinal function in rat model. Arch Pharm Res. 2006;29:348-53 pubmed
    ..This finding bolsters the notion that Chinese yam extract may prove helpful as a digestion-aiding agent for patients suffering from hyperglycemia or hyperlipidemia...
  66. Scarcelli N, Tostain S, Vigouroux Y, Luong V, Baco M, Agbangla C, et al. Genetic structure of farmer-managed varieties in clonally-propagated crops. Genetica. 2011;139:1055-64 pubmed publisher
    ..Each variety could thus be interpreted as being the product of sexual reproduction having evolved by mutation. This highly structured diversity of farmer-managed varieties has consequences for the preservation of yam diversity...
  67. Sautour M, Mitaine Offer A, Miyamoto T, Dongmo A, Lacaille Dubois M. A new steroidal saponin from Dioscorea cayenensis. Chem Pharm Bull (Tokyo). 2004;52:1353-5 pubmed
    ..methyl protodioscin (2), asperoside (3) and prosapogenin A of dioscin (4) were isolated from the rhizomes of Dioscorea cayenensis LAM.-HOLL (Dioscoreaceae)...
  68. Li P, Mao Z, Lou J, Li Y, Mou Y, Lu S, et al. Enhancement of diosgenin production in Dioscorea zingiberensis cell cultures by oligosaccharides from its endophytic fungus Fusarium oxysporum Dzf17. Molecules. 2011;16:10631-44 pubmed publisher
    ..fungus Fusarium oxysporum Dzf17 as elicitors on diosgenin production in cell suspension cultures of its host Dioscorea zingiberensis were investigated...
  69. Cai X, Shan T, Li P, Huang Y, Xu L, Zhou L, et al. Spirobisnaphthalenes from the endophytic fungus Dzf12 of Dioscorea zingiberensis and their antimicrobial activities. Nat Prod Commun. 2009;4:1469-72 pubmed
    ..4), and diepoxin gamma (5), were isolated from the endophytic fungus Dzf12 associated with the medicinal plant Dioscorea zingiberensis C. H. Wright. Their structures were identified by physicochemical and spectrometric analysis...
  70. McKoy M, Omoruyi F, Simon O, Asemota H. Investigation of the effects of a sapogenin-rich preparation from a Jamaican yam (Dioscorea sp.) on blood cholesterol levels in rats. Proc West Pharmacol Soc. 2003;46:156-9 pubmed
  71. Narula A, Kumar S, Srivastava P. Genetic fidelity of in vitro regenerants, encapsulation of shoot tips and high diosgenin content in Dioscorea bulbifera L., a potential alternative source of diosgenin. Biotechnol Lett. 2007;29:623-9 pubmed
    b>Dioscorea bulbifera L. containing the pharmaceutically important compound, diosgenin, was regenerated in vitro through nodal segments on supplemented Murashige and Skoog medium (MS)...