cornus

Summary

Summary: A plant genus of the family CORNACEAE. It is widely cultivated for the attractive flowers.

Top Publications

  1. Jayaprakasam B, Olson L, Schutzki R, Tai M, Nair M. Amelioration of obesity and glucose intolerance in high-fat-fed C57BL/6 mice by anthocyanins and ursolic acid in Cornelian cherry (Cornus mas). J Agric Food Chem. 2006;54:243-8 pubmed
    ..Cornelian cherries (Cornus mas) are used in the preparation of beverages in Europe and also to treat diabetes-related disorders in Asia...
  2. Leskovac A, Joksic G, Jankovic T, Savikin K, Menkovic N. Radioprotective properties of the phytochemically characterized extracts of Crataegus monogyna, Cornus mas and Gentianella austriaca on human lymphocytes in vitro. Planta Med. 2007;73:1169-75 pubmed
    ..Rosaceae) fruit, Cornus mas L. (Cornaceae) leaves and Gentianella austriaca (A. Kern. & Jos. Kern...
  3. Feild T, Lee D, Holbrook N. Why leaves turn red in autumn. The role of anthocyanins in senescing leaves of red-osier dogwood. Plant Physiol. 2001;127:566-74 pubmed
    ..Here, we provide evidence for red-osier dogwood (Cornus stolonifera) that anthocyanins form a pigment layer in the palisade mesophyll layer that decreases light capture ..
  4. Svendsen E, Wilen R, Stevenson R, Liu R, Tanino K. A molecular marker associated with low-temperature induction of dormancy in red osier dogwood (Cornus sericea). Tree Physiol. 2007;27:385-97 pubmed
    ..An F2 population (191 plants) red osier dogwood (Cornus sericea L...
  5. Kam S, Do J, Choi J, Jeon B, Roh G, Hyun J. In vivo and in vitro animal investigation of the effect of a mixture of herbal extracts from Tribulus terrestris and Cornus officinalis on penile erection. J Sex Med. 2012;9:2544-51 pubmed publisher
    ..Herbal preparations have long been used as folk remedies for erectile dysfunction (ED)...
  6. Karlson D, Xiang Q, Stirm V, Shirazi A, Ashworth E. Phylogenetic analyses in cornus substantiate ancestry of xylem supercooling freezing behavior and reveal lineage of desiccation related proteins. Plant Physiol. 2004;135:1654-65 pubmed
    ..Here we use Cornus as a model system to provide the first phylogenetic characterization of xylem freezing behavior and dehydrin-like ..
  7. Kim D, Park K, Lee S, Lee S, Hwang J. Cornus kousa F.Buerger ex Miquel increases glucose uptake through activation of peroxisome proliferator-activated receptor ? and insulin sensitization. J Ethnopharmacol. 2011;133:803-9 pubmed publisher
    b>Cornus kousa F.Buerger ex Miquel, an oriental medicinal plant, has been traditionally used for the treatment of hyperglycemia, but its molecular mechanism remains unknown...
  8. Lee J, Jang D, Kim N, Lee Y, Kim J, Kim J. Galloyl glucoses from the seeds of Cornus officinalis with inhibitory activity against protein glycation, aldose reductase, and cataractogenesis ex vivo. Biol Pharm Bull. 2011;34:443-6 pubmed
    ..and gallic acid 4-O-?-D-(6'-O-galloyl)-glucoside (8), were isolated from an EtOAc-soluble fraction of the seeds of Cornus officinalis (Cornaceae)...
  9. Xu H, Shen J, Liu H, Shi Y, Li L, Wei M. Morroniside and loganin extracted from Cornus officinalis have protective effects on rat mesangial cell proliferation exposed to advanced glycation end products by preventing oxidative stress. Can J Physiol Pharmacol. 2006;84:1267-73 pubmed
    ..We postulate that morroniside and loganin, 2 components extracted from Cornus officinalis, may ameliorate the detrimental effects of AGE-induced MCs proliferation by preventing oxidative ..

More Information

Publications89

  1. Cho K, Lee H, Lee S, Woo H, Lee M, Seok J, et al. Oleanolic acid and ursolic acid derived from Cornus officinalis Sieb. et Zucc. suppress epidermal growth factor- and phorbol ester-induced MUC5AC mucin production and gene expression from human airway epithelial cells. Phytother Res. 2011;25:760-4 pubmed publisher
    ..These results suggest that oleanolic acid and ursolic acid can regulate mucin gene expression, and production of mucin protein, by directly acting on airway epithelial cells...
  2. Chang J, Chiang L, Hsu F, Lin C. Chemoprevention against hepatocellular carcinoma of Cornus officinalis in vitro. Am J Chin Med. 2004;32:717-25 pubmed
    The water extracts of Cornus officinalis Sieb. et Zuce against hepatocellular carcinoma (HCC) was studied for its chemopreventive potential...
  3. Hsu J, Wu Y, Liu I, Cheng J. Release of acetylcholine to raise insulin secretion in Wistar rats by oleanolic acid, one of the active principles contained in Cornus officinalis. Neurosci Lett. 2006;404:112-6 pubmed
    The plasma glucose lowering action of fruits of cornus (Cornus officinalis), the major active constituent of Die-Huang-Wan, has been documented to mediate acetylcholine (ACh) release, which in turn to stimulate muscarinic M(3) receptors ..
  4. He Y, Ma G, Peng J, Ma Z, Hamann M. Liver X receptor and peroxisome proliferator-activated receptor agonist from Cornus alternifolia. Biochim Biophys Acta. 2012;1820:1021-6 pubmed publisher
    ..From the previous screening of several medicinal plants for potential partial PPAR? agonists, the extracts of Cornus alternifolia were found to exhibit promising bioactivity...
  5. Liu X, Feng C, FRANKS R, Qu R, Xie D, Xiang Q. Plant regeneration and genetic transformation of C. canadensis: a non-model plant appropriate for investigation of flower development in Cornus (Cornaceae). Plant Cell Rep. 2013;32:77-87 pubmed publisher
    ..for investigation of genetic and molecular mechanisms involved in inflorescence architectures in Cornus species...
  6. Zhang L, Ren L, Wun J. [Studies on pharmacokinetics of loganin and morroniside in Cornus officinalis injection in mice]. Zhongguo Zhong Yao Za Zhi. 2003;28:509-12 pubmed
    To establish a revered-phase HPLC method for the study of pharmacokinetics of loganin and morroniside in Cornus officinalis injectionin mice after a single oral and intravenous administrations.
  7. Cao G, Cai H, Cai B, Tu S. Effect of 5-hydroxymethylfurfural derived from processed Cornus officinalis on the prevention of high glucose-induced oxidative stress in human umbilical vein endothelial cells and its mechanism. Food Chem. 2013;140:273-9 pubmed publisher
    ..the pharmacological application of 5-HMF for preventing cardiovascular and diabetes mellitus diseases, and provides the theoretical basis for further development of a Cornus officinalis agent for diabetes-associated vascular diseases.
  8. Qian D, Zhu Y, Zhu Q. [Effect of alcohol extract of Cornus officinalis Sieb. et Zucc on GLUT4 expression in skeletal muscle in type 2 (non-insulin-dependent) diabetic mellitus rats]. Zhongguo Zhong Yao Za Zhi. 2001;26:859-62 pubmed
    ..postprandial plasma glucose and increasing insulin level in non-insulin-dependent diabetic mellitus (NIDDM) rats, we studied the effects of Alcohol extract of Cornus officinalis Sieb. et Zucc on the GLUT4 expression in NIDDM model rats.
  9. Babu D, Thapa D, Lee J, Park S, Kim A, Kim Y, et al. Inhibitory effects of an aqueous extract of Cornus kousa Burg. leaves on TNF-alpha-induced chemokine expression and monocyte adhesion to human colonic epithelial cells. Arch Pharm Res. 2009;32:91-8 pubmed publisher
    An aqueous extract of Cornus kousa Burg. leaves (ACK) that contained high amount of polyphenols showed significant antioxidant activity against diphenylpicrylhydrazyl (DPPH) radicals and TNF-alpha-generated reactive oxygen species...
  10. Xiang Q, Manchester S, Thomas D, Zhang W, Fan C. Phylogeny, biogeography, and molecular dating of cornelian cherries (Cornus, Cornaceae): tracking Tertiary plant migration. Evolution. 2005;59:1685-700 pubmed
    ..the phylogeny and biogeographic history of an intercontinentally disjunct plant group, the cornelian cherries of Cornus (dogwoods)...
  11. Vareed S, Reddy M, Schutzki R, Nair M. Anthocyanins in Cornus alternifolia, Cornus controversa, Cornus kousa and Cornus florida fruits with health benefits. Life Sci. 2006;78:777-84 pubmed
    The anthocyanins in native Cornus alternifolia, Cornus controversa, Cornus kousa and Cornus florida were quantified by HPLC and characterized by spectroscopic methods. The analyses of C. alternifolia and C...
  12. Ding X, Wang M, Yu Z, Hu W, Cai B. [Studies on separation, appraisal and the biological activity of 5-HMF in Cornus officinalis]. Zhongguo Zhong Yao Za Zhi. 2008;33:392-6, 484 pubmed
    To develop the mechanism of improving protection function of prepared Cornus officinalis for liver and kidney and the biological activity of 5-hydroxymethylfurfural (5-HMF).
  13. Seeram N, Schutzki R, Chandra A, Nair M. Characterization, quantification, and bioactivities of anthocyanins in Cornus species. J Agric Food Chem. 2002;50:2519-23 pubmed
    b>Cornus mas, Cornus officinalis, Cornus controversa, and Cornus kousa (Cornaceae) bear edible fruits that are consumed in parts of Europe and Asia...
  14. Feng C, Xiang Q, Franks R. Phylogeny-based developmental analyses illuminate evolution of inflorescence architectures in dogwoods (Cornus s. l., Cornaceae). New Phytol. 2011;191:850-69 pubmed publisher
    ..The developmental pathways of six species of Cornus producing different inflorescence types were characterized by scanning electron microscopy (SEM) and histological ..
  15. Fan C, Xiang Q, Remington D, Purugganan M, Wiegmann B. Evolutionary patterns in the antR-Cor gene in the dwarf dogwood complex (Cornus, Cornaceae). Genetica. 2007;130:19-34 pubmed
    ..pattern of the myc-like anthocyanin regulatory gene antR-Cor was examined in the dwarf dogwood species complex (Cornus Subgenus Arctocrania) that contains two diploid species (C. canadensis and C...
  16. Wu V, Qiu X, Peggy Hsieh Y. Evaluation of Escherichia coli O157:H7 in apple juice with Cornus fruit (Cornus officinalis Sieb. et Zucc.) extract by conventional media and thin agar layer method. Food Microbiol. 2008;25:190-5 pubmed
    Escherichia coli O157:H7 survival in apple juice supplemented with Cornus fruit (Cornus officinalis Sieb. et Zucc.) extract was studied. Inoculated samples with or without Cornus fruit extract were kept at 21 and 7 degrees C...
  17. Bjorøy O, Fossen T, Andersen O. Anthocyanin 3-galactosides from Cornus alba 'Sibirica' with glucosidation of the B-ring. Phytochemistry. 2007;68:640-5 pubmed
    ..4) and cyanidin (5) were isolated from the bluish white berries and compound umbel of Siberian dogwood, Cornus alba 'Sibirica'...
  18. Du W, Wang M, Cai B. [Effect of polysaccharides in crude and processed Cornus officinalis on the immunologic function of mice with immunosuppression induced]. Zhong Yao Cai. 2008;31:715-7 pubmed
    To investigate the effect of polysaccharides in crude and processed Cornus officinalis on the immunologic function of mice with immunosuppression induced.
  19. Zhuang X, Klingeman W, Hu J, Chen F. Emission of volatile chemicals from flowering dogwood (cornus Florida L.) flowers. J Agric Food Chem. 2008;56:9570-4 pubmed publisher
    ..The implications of the findings of this study to dogwood breeding programs are discussed...
  20. Sultana N, Lee N. Antielastase and free radical scavenging activities of compounds from the stems of Cornus kousa. Phytother Res. 2007;21:1171-6 pubmed
    Bioassay-guided investigation of the stems of Cornus kousa led to the isolation of 12 compounds such as four triterpenoids: betulinic acid (1), maslinic acid (2), arjunolic acid (3), 3-isoarjunolic acid (4), four flavanoids; catechin (5), ..
  21. Frank S, Anderson A, Ranger C. Interaction of Insecticide and Media Moisture on Ambrosia Beetle (Coleoptera: Curculionidae) Attacks on Selected Ornamental Trees. Environ Entomol. 2017;: pubmed publisher
    ..During trials in spring 2013 and 2015, flooded Cornus florida and Cornus kousa were heavily attacked despite sprays with permethrin, but nonflooded C. kousa or C...
  22. Kaliszewski M, Kennedy A, Blaes S, Shaffer R, Knott A, Song W, et al. SOD1 Lysine 123 Acetylation in the Adult Central Nervous System. Front Cell Neurosci. 2016;10:287 pubmed publisher
    ..Ac-K123 SOD1 staining was strong in the fimbria, subiculum, pyramidal cells and Schaffer collateral fibers of the cornus ammonis field 1 (CA1) region and granule and neuronal progenitor cells of the dentate gyrus...
  23. Wang W, Xu J, Li L, Wang P, Ji X, Ai H, et al. Neuroprotective effect of morroniside on focal cerebral ischemia in rats. Brain Res Bull. 2010;83:196-201 pubmed publisher
    b>Cornus officinalis Sieb. et Zucc., known as Shan-zhu-yu in Chinese, has been used to treat cerebrovascular disease and diabetes in Traditional Chinese Medicine for a long time and morroniside is the main component of Shan-zhu-yu...
  24. Bruinenberg V, van Vliet D, Attali A, de Wilde M, Kuhn M, van Spronsen F, et al. A Specific Nutrient Combination Attenuates the Reduced Expression of PSD-95 in the Proximal Dendrites of Hippocampal Cell Body Layers in a Mouse Model of Phenylketonuria. Nutrients. 2016;8:185 pubmed publisher
    ..in the hippocampus, specifically in the granular cell layer of the dentate gyrus, with a similar trend seen in the cornus ammonis 1 (CA1) and cornus ammonis 3 (CA3) pyramidal cell layer...
  25. Song Q, Dong X, Yu X. [Effects of traditional chinese medicine Fructus psoraleae on differentiation of mouse osteoblastic MC3T3-e1 cell in vitro]. Zhongguo Zhong Yao Za Zhi. 2009;34:1264-7 pubmed
    ..2 g x L(-1) for 14-21 days. F. psoralea can stimulate the differentiation of osteoblasts in vitro. It will offer a reference for the active mechanism research. ..
  26. Zhao M, Qian D, Shang E, Jiang S, Guo J, Liu P, et al. Comparative pharmacokinetics of the main compounds of Shanzhuyu extract after oral administration in normal and chronic kidney disease rats. J Ethnopharmacol. 2015;173:280-6 pubmed publisher
    ..and doxorubicin-induced chronic kidney disease (CKD) rat plasma after oral administration of Shanzhuyu (fruit of Cornus officinalis) extract. Both calibration curves gave satisfactory linearity (r>0.99) at linear range of 1.96-1962...
  27. Yamabe N, Noh J, Park C, Kang K, Shibahara N, Tanaka T, et al. Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice. Eur J Pharmacol. 2010;648:179-87 pubmed publisher
    ..Loganin exhibits protective effects against hepatic injury and other diabetic complications associated with abnormal metabolic states and inflammation caused by oxidative stress and advanced glycation endproduct formation. ..
  28. Qi M, Liu H, Dai D, Li N, Dai Y. Total triterpene acids, active ingredients from Fructus Corni, attenuate diabetic cardiomyopathy by normalizing ET pathway and expression of FKBP12.6 and SERCA2a in streptozotocin-rats. J Pharm Pharmacol. 2008;60:1687-94 pubmed publisher
    Total triterpene acids (TTAs) isolated from Cornus officinalis Sieb., one of the herbs contained in Liuwei Dihuang decoction, were aimed at alleviating diabetic cardiomyopathy...
  29. Powell T, Hood G, Murphy M, Heilveil J, Berlocher S, Nosil P, et al. Genetic divergence along the speciation continuum: the transition from host race to species in rhagoletis (Diptera: tephritidae). Evolution. 2013;67:2561-76 pubmed publisher
    ..populations of Rhagoletis pomonella to their sister taxon, the undescribed flowering dogwood fly attacking Cornus florida...
  30. Yao R, Zhang L, Wang W, Li L. Cornel iridoid glycoside promotes neurogenesis and angiogenesis and improves neurological function after focal cerebral ischemia in rats. Brain Res Bull. 2009;79:69-76 pubmed publisher
    ..investigate the effects of cornel iridoid glycoside (CIG), an ingredient extracted from a traditional Chinese herb Cornus officinalis, on neurological function and neurogenesis after ischemic stroke...
  31. Naumburg E, Ellsworth D. Short-term light and leaf photosynthetic dynamics affect estimates of daily understory photosynthesis in four tree species. Tree Physiol. 2002;22:393-401 pubmed
  32. Zhang G, Qi Y, Lou Z, Liu C, Wu X, Chai Y. Determination of oleanolic acid and ursolic acid in cornel by cyclodextrin-modified micellar electrokinetic chromatography. Biomed Chromatogr. 2005;19:529-32 pubmed
    ..9% (ursolic acid). The limits of detection were 1.6 microg/mL for both components. The method proved to be sensitive, rapid, accurate and suitable for the determination of oleanolic acid and ursolic acid in cornel. ..
  33. Rajput S, Sharma A, Meena C, Pant A, Jain R, Sharma S. Effect of L-pGlu-(1-benzyl)-l-His-l-Pro-NH2 against in-vitro and in-vivo models of cerebral ischemia and associated neurological disorders. Biomed Pharmacother. 2016;84:1256-1265 pubmed publisher
    ..Moreover, L-pGlu-(1-benzyl)-l-His-l-Pro-NH2 resulted in a substantial reduction in CA1 (Cornus Ammonis 1) hippocampal neuronal cell death, inflammatory cytokines, TNF-?, IL-6 and oxidative stress in ..
  34. Sozanski T, Kucharska A, Rapak A, Szumny D, Trocha M, Merwid Lad A, et al. Iridoid-loganic acid versus anthocyanins from the Cornus mas fruits (cornelian cherry): Common and different effects on diet-induced atherosclerosis, PPARs expression and inflammation. Atherosclerosis. 2016;254:151-160 pubmed publisher
    ..Our results also indicate the potential health benefits of fruits containing anthocyanins and iridoids, and support the idea of creating composed phytopharmaceuticals containing both groups of substances. ..
  35. Jiang W, Chen X, Zhu H, Tian J. Effect of cornuside on experimental sepsis. Planta Med. 2009;75:614-9 pubmed publisher
    ..This work provides first evidence for the clinic use of cornuside as a new immunomodulatory drug that has the capacity to inhibit the inflammatory response in sepsis. ..
  36. Celep E, Aydin A, Kirmizibekmez H, Yesilada E. Appraisal of in vitro and in vivo antioxidant activity potential of cornelian cherry leaves. Food Chem Toxicol. 2013;62:448-55 pubmed publisher
    The antioxidant activity of the 80% methanolic extract of Cornus mas L. leaves (CMM) was evaluated by various methods both in vitro and in vivo...
  37. Yousefi B, Abasi M, Abbasi M, Jahanban Esfahlan R. Anti-Proliferative Properties of Cornus mass Fruit in Different Human Cancer Cells. Asian Pac J Cancer Prev. 2015;16:5727-31 pubmed
    ..b>Cornus mas (CM) fruit is well known for its antioxidant activities; however, its toxicity against human cancers needs to ..
  38. Xue J, Zhang A, Wang Y, Sheng W. [Study on plant tissue culture of Cornus officinalis]. Zhongguo Zhong Yao Za Zhi. 2003;28:118-21 pubmed
    To set up the optimums of tissue culture for Cornus officinalis. A section of stems of the fine varieties of Cornus officinalis were strictly sterilized, cultivated and geminated in medium with addition of different kinds of hormone...
  39. Asgary S, Kelishadi R, Rafieian Kopaei M, Najafi S, Najafi M, Sahebkar A. Investigation of the lipid-modifying and antiinflammatory effects of Cornus mas L. supplementation on dyslipidemic children and adolescents. Pediatr Cardiol. 2013;34:1729-35 pubmed publisher
    b>Cornus mas L. (CM) fruits are rich in anthocyanins and possess both antiinflammatory and antioxidant activities...
  40. Battey N. Plant culture: thirteen seasonal pieces. October--the unnatural knowledge of colour. J Exp Bot. 2003;54:2197-200 pubmed
  41. Antolak H, Czyzowska A, Sakač M, Mišan A, Đuragić O, Kregiel D. Phenolic Compounds Contained in Little-known Wild Fruits as Antiadhesive Agents Against the Beverage-Spoiling Bacteria Asaia spp. Molecules. 2017;22: pubmed publisher
    ..i>Sambucusnigra), lingonberry (Vacciniumvitis-idaea) and cornelian cherry (Cornusmas), and their action against adhesion of bacterial strains of Asaialannensis and ..
  42. Gong Y, Chen K, Yu S, Liu H, Qi M. [Protective effect of terpenes from fructus corni on the cardiomyopathy in alloxan-induced diabetic mice]. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2012;28:378-80, 384 pubmed
    ..The above change was improved significantly. TFC ameliorated the alterations of cardiomyopathy in diabetic mice induced by alloxan. the mechanism might be related to decrease blood glucose, antioxidative stress and inflammatory factors. ..
  43. Forbes A, Fisher J, Feder J. Habitat avoidance: overlooking an important aspect of host-specific mating and sympatric speciation?. Evolution. 2005;59:1552-9 pubmed
    ..of their natal fruit, apple and hawthorn flies, and their undescribed sister species infesting flowering dogwood (Cornus florida), also avoid the odors of nonnatal fruit...
  44. Ding X, Wang M, Yao Y, Li G, Cai B. Protective effect of 5-hydroxymethylfurfural derived from processed Fructus Corni on human hepatocyte LO2 injured by hydrogen peroxide and its mechanism. J Ethnopharmacol. 2010;128:373-6 pubmed publisher
  45. Liu J, Franks R, Feng C, Liu X, Fu C, Jenny Xiang Q. Characterization of the sequence and expression pattern of LFY homologues from dogwood species (Cornus) with divergent inflorescence architectures. Ann Bot. 2013;112:1629-41 pubmed publisher
    ..umbel-like and inflorescences with elongated internodes) in closely related lineages in the dogwood genus (Cornus s.l.)...
  46. Gebre G, Tschaplinski T. Solute accumulation of chestnut oak and dogwood leaves in response to throughfall manipulation of an upland oak forest. Tree Physiol. 2002;22:251-60 pubmed
    ..Leaf samples of overstory and understory chestnut oak (Quercus prinus L.) and understory dogwood (Cornus florida L...
  47. Kuroda K, Kasuga J, Arakawa K, Fujikawa S. Xylem ray parenchyma cells in boreal hardwood species respond to subfreezing temperatures by deep supercooling that is accompanied by incomplete desiccation. Plant Physiol. 2003;131:736-44 pubmed
    ..Betula platyphylla Sukat. var japonica Hara, Betula pubescens Ehrh., and red osier dogwood (Cornus sericea), in which XRPCs have been reported to respond by extracellular freezing...
  48. Holzmueller E, Jose S, Jenkins M. The relationship between fire history and an exotic fungal disease in a deciduous forest. Oecologia. 2008;155:347-56 pubmed
    ..We examined Cornus florida populations in burned and unburned Quercus-Carya stands to determine if burning prior to anthracnose ..
  49. Bergh J, Leskey T, Walgenbach J, Klingeman W, Kain D, Zhang A. Dogwood borer (Lepidoptera: Sesiidae) abundance and seasonal flight activity in apple orchards, urban landscapes, and woodlands in five eastern states. Environ Entomol. 2009;38:530-8 pubmed
    ..Captures at woodland sites tended to occur predominantly from mid-May through about mid-June and were very sporadic thereafter...
  50. Zhang H, Dong Y, Hu S, Ren S. [The comparison about inhibition of five Chinese herbal medicines to two different resources alpha-glycosidase]. Zhong Yao Cai. 2008;31:1024-7 pubmed
    ..To compare alpha-glycosidase inhibitor microamount screening models which are established by two different resources alpha-glycosidase to screen the Chinese herbal medicines which have great alpha-glycosidase inhibition...
  51. Edwards J, Whitaker D, Klionsky S, Laskowski M. Botany: a record-breaking pollen catapult. Nature. 2005;435:164 pubmed
    ..Here we describe how the flower stamens of the bunchberry dogwood (Cornus canadensis) rely on this principle to catapult pollen into the air as the flower opens explosively...
  52. Park K, Yin J, Yoon K, Hwang Y, Lee M. Antiproliferative Effects of New Dimeric Ellagitannin from Cornus alba in Prostate Cancer Cells Including Apoptosis-Related S-Phase Arrest. Molecules. 2016;21:137 pubmed publisher
    Activity-guided isolation of 80% acetone extract of Cornus alba, which is traditionally used as an anti-inflammatory, hemostatic and diuretic in Korea, yielded one novel compound, tentatively designated cornusiin H (13), together with 12 ..
  53. Jiang W, Zhang S, Hou J, Zhu H. Effect of loganin on experimental diabetic nephropathy. Phytomedicine. 2012;19:217-22 pubmed publisher
    ..Loganin, an iridoid glucoside compound was isolated from Cornus officinalis Sieb. et Zucc...
  54. Li C, Zhang G, Shi T, Dong X, Sun P, Li D, et al. [Experimental study on effect of the water extract of dogwood fruits on the liver and testis in rats model of kidney-yang deficiency]. Zhongguo Zhong Yao Za Zhi. 2003;28:743-6 pubmed
    ..To explore the effect of Dogwood fruits on tonifying kidney-yang...
  55. Krosniak M, Gastoł M, Szałkowski M, Zagrodzki P, Derwisz M. Cornelian cherry (cornus MAS L.) juices as a source of minerals in human diet. J Toxicol Environ Health A. 2010;73:1155-8 pubmed publisher
    The aim of this study was to determine the mineral content of Cornelian cherry (Cornus mas L.), as this fruit and its preservatives may be considered as important nutritional supplements...
  56. Miller S, Masuya H, Zhang J, Walsh E, Zhang N. Real-Time PCR Detection of Dogwood Anthracnose Fungus in Historical Herbarium Specimens from Asia. PLoS ONE. 2016;11:e0154030 pubmed publisher
    b>Cornus species (dogwoods) are popular ornamental trees and important understory plants in natural forests of northern hemisphere. Dogwood anthracnose, one of the major diseases affecting the native North American Cornus species, such as C...
  57. Jenkins M, Jose S, White P. Impacts of an exotic disease and vegetation change on foliar calcium cycling in Appalachian forests. Ecol Appl. 2007;17:869-81 pubmed
    Because of the high calcium content of its foliage, Cornus florida (flowering dogwood) has been described as a calcium "pump" that draws calcium from deeper mineral soil and enriches surface soil horizons...
  58. Cao G, Zhang C, Zhang Y, Cong X, Cai H, Cai B. Screening and identification of potential active components in crude Fructus Corni using solid-phase extraction and LC-LTQ-linear ion trap mass spectrometry. Pharm Biol. 2012;50:278-83 pubmed publisher
    Fructus Corni is derived from the dry ripe sarcocarp of Cornus officinalis Sieb. et Zucc. (Cornaceae). It has attracted increasingly much attention as one of the most popular and valuable herbal medicine in clinic...
  59. Lee S, Kim S, Han S, Kim H, Ham S, Kang I. Corni fructus scavenges hydroxy radicals and decreases oxidative stress in endothelial cells. J Med Food. 2006;9:594-8 pubmed
    ..This study demonstrates that corni fructus is a potent antioxidant substance, and suggests that further investigation is needed to characterize the difference between extract types and to identify its antioxidant compounds...
  60. Li G, Yao Y, Ding X. [Studies on chemistry component and the biological activity of petroleum ether extraction from pre-and post-processed of Cornus officinalis]. Zhong Yao Cai. 2010;33:192-5 pubmed
    ..basis for improving pharmacodynamics by comparing the chemical constituents of petroleum ether extraction from crude and processed Cornus officinalis and the effects on the immunologic function of mice with immunosuppression induced.
  61. Nojima S, Linn C, Roelofs W. Identification of host fruit volatiles from flowering dogwood (Cornus florida) attractive to dogwood-origin Rhagoletis pomonella flies. J Chem Ecol. 2003;29:2347-57 pubmed
    ..coupled with electroantennographic detection were used to identify volatiles from fruit of flowering dogwood, Cornus florida, as key attractants for Rhagoletis pomonella flies originating from dogwood fruit...
  62. Vander Wall S, Kuhn K, Gworek J. Two-phase seed dispersal: linking the effects of frugivorous birds and seed-caching rodents. Oecologia. 2005;145:282-7 pubmed
  63. Ding X, Zhu F, Yu Z, Dong L, Cai B. [Comparative study on contents of amino acid and major and trace elements in Cornus officinalis before and after being processed]. Zhong Yao Cai. 2007;30:396-9 pubmed
    To investigate amino acid and inorganic element in cornus officinalis and study the effects of processed on contents of them.
  64. Savikin K, Zdunic G, Jankovic T, Stanojkovic T, Juranic Z, Menkovic N. In vitro cytotoxic and antioxidative activity of Cornus mas and Cotinus coggygria. Nat Prod Res. 2009;23:1731-9 pubmed publisher
    Cytotoxicity and antioxidant properties of the methanol extracts of leaves and flowers of Cornus mas and Cotinus coggygria were studied, together with their chemical composition. Extracts of C...
  65. Shao X, Luo Q, Qin Q, Qiu G, Li Z. [Effect of fructus corni polysaccharides on damaged sexual function of male rats]. Zhongguo Zhong Yao Za Zhi. 2010;35:772-5 pubmed
    ..To observe the effects of Fructus Corni polysaccharides (FCP) on sexual function of hemicastrated rats...
  66. Fu J, Zhang X, Liu K, Li Q, Zhang L, Yang X, et al. Hypolipidemic activity in Sprague-Dawley rats and constituents of a novel natural vegetable oil from Cornus wilsoniana fruits. J Food Sci. 2012;77:H160-9 pubmed publisher
    b>Cornus wilsoniana Wanger is a woody oil plant distributed in the south region of the Yellow River, China...
  67. Youn K, Jun M. Inhibitory effects of key compounds isolated from Corni fructus on BACE1 Activity. Phytother Res. 2012;26:1714-8 pubmed publisher
    ..These novel findings suggest that Corni fructus contains biologically active components that may be used to attenuate the progression and/or prevention of Alzheimer's disease...
  68. Nawirska Olszańska A, Biesiada A, Sokół Łętowska A, Kucharska A. Content of bioactive compounds and antioxidant capacity of pumpkin puree enriched with japanese quince, cornelian cherry, strawberry and apples. Acta Sci Pol Technol Aliment. 2011;10:51-60 pubmed
    ..Hence, it is recommended to blend pumpkin with other fruits, which are aromatic, have a defined taste, and contain a large quantity of active ingredients and organic acids to improve its palatibility...
  69. Jeong E, Kim T, Yang H, Kang S, Kim S, Sung S, et al. Neuroprotective iridoid glycosides from Cornus officinalis fruits against glutamate-induced toxicity in HT22 hippocampal cells. Phytomedicine. 2012;19:317-21 pubmed publisher
    The methanolic extract of the fruits of Cornus officinalis S et Z. (Cornaceae) showed the significant neuroprotective activity against glutamate-induced toxicity in HT22 hippocampal cells...
  70. Kim K, Choi S, Kim Y, Lee K. Tirucallane triterpenoids from Cornus walteri. J Nat Prod. 2011;74:54-9 pubmed publisher
    ..deoxyflindissone (13) and (-)-leucophyllone (14), were isolated from a MeOH extract of stems and stem bark of Cornus walteri...
  71. Park C, Cho E, Yokozawa T. Protection against hypercholesterolemia by Corni fructus extract and its related protective mechanism. J Med Food. 2009;12:973-81 pubmed publisher
    ..In conclusion, Corni Fructus may protect against CVD by regulating blood pressure, cholesterol levels, and expression of proteins related to lipid metabolism...
  72. Yu H, Hur J, Seo S, Moon H, Kim H, Park R, et al. Protective effect of ursolic acid from Cornus officinalis on the hydrogen peroxide-induced damage of HEI-OC1 auditory cells. Am J Chin Med. 2009;37:735-46 pubmed
    The fruits of Cornus officinalis have been used in traditional oriental medicine for treatment of inner ear diseases, such as tinnitus and hearing loss. In the present study, we investigated the protective effect of C...
  73. Chen S, Dong C, Yang J, Ji C, Zhang Y. [A survey of Cornus officinalis varieties]. Zhong Yao Cai. 2002;25:305-6 pubmed
    According to the survey of Cornus officinalis in the main planting areas of Henan, Zhejiang and Shanxi province, the fruit shape can be divided into seven types, cylindricform, ellipticform, long pear-shape, short pear-shape, long ..
  74. Han S, Pan Y, Yang G, Cai B. [Research on components of Cornus officinalis extracted by supercritical carbon dioxide]. Zhongguo Zhong Yao Za Zhi. 2003;28:1148-50, 1183 pubmed
    To study the chemical constituents of Cornus officinalis extracted by supercritical carbon dioxide fluid extraction (SFE).
  75. Lambert J, Lampen P, von Bohlen A, Hergenröder R. Two- and three-dimensional mapping of the iron distribution in the apoplastic fluid of plant leaf tissue by means of magnetic resonance imaging. Anal Bioanal Chem. 2006;384:231-6 pubmed
    ..The new technique was applied to a leaf of red stem dogwood (Cornus stolonifera)...
  76. Karlson D, Zeng Y, Stirm V, Joly R, Ashworth E. Photoperiodic regulation of a 24-kD dehydrin-like protein in red-osier dogwood (Cornus sericea L.) in relation to freeze-tolerance. Plant Cell Physiol. 2003;44:25-34 pubmed
    A predominant 24-kD dehydrin-like protein was previously found to fluctuate seasonally within red-osier dogwood (Cornus sericea L.) stems...
  77. Liu Z, Zhu Z, Zhang H, Tan G, Chen X, Chai Y. Qualitative and quantitative analysis of Fructus Corni using ultrasound assisted microwave extraction and high performance liquid chromatography coupled with diode array UV detection and time-of-flight mass spectrometry. J Pharm Biomed Anal. 2011;55:557-62 pubmed publisher
    ..Significant variations were demonstrated in the contents of seven compounds. Further 13 components were tentatively identified by online TOF mass analysis...
  78. Nawa Y, Endo J, Ohta T. The inhibitory effect of the components of Cornus officinalis on melanogenesis. J Cosmet Sci. 2007;58:505-17 pubmed
    Five known compounds were isolated from a Cornus officinalis 50% ethanol extract (C. officinalis extract) and a hot water extract. We investigated the photochemical and pharmacological active compounds of C...
  79. Xiang Q, Thorne J, Seo T, Zhang W, Thomas D, Ricklefs R. Rates of nucleotide substitution in Cornaceae (Cornales)-Pattern of variation and underlying causal factors. Mol Phylogenet Evol. 2008;49:327-42 pubmed publisher
    ..present study, we examined the rate and pattern of molecular evolution for five DNA regions over a phylogeny of Cornus, the single genus of Cornaceae...
  80. Su W, Dai D, Liu H, Na T, Dai Y. Upregulated endothelin system in diabetic vascular dysfunction and early retinopathy is reversed by CPU0213 and total triterpene acids from Fructus Corni. Clin Exp Pharmacol Physiol. 2007;34:1228-33 pubmed
    ..Total triterpene acid, in terms of pharmacological properties resembling the endothelin receptor antagonist CPU0213, is effective in normalizing expression of the ET system and iNOS in early diabetic retinopathy and vasculaopathy...