Summary: A plant genus of the family BRASSICACEAE known for the root used in hot SPICES. It is also the source of HORSERADISH PEROXIDASE which is widely used in laboratories.

Top Publications

  1. Tedeschi P, Leis M, Pezzi M, Civolani S, Maietti A, Brandolini V. Insecticidal activity and fungitoxicity of plant extracts and components of horseradish (Armoracia rusticana) and garlic (Allium sativum). J Environ Sci Health B. 2011;46:486-90 pubmed publisher
    ..The objective of this study is to determine the insecticidal and anti-fungal activity of Armoracia rusticana and Allium sativum L. extracts against larvae of Aedes albopictus (Skuse) and some pathogenic fungi...
  2. Flocco C, Giulietti M. Effect of chitosan on peroxidase activity and isoenzyme profile in hairy root cultures of Armoracia lapathifolia. Appl Biochem Biotechnol. 2003;110:175-83 pubmed
    Hairy root cultures of Armoracia lapathifolia established by infection with Agrobacterium rhizogenes LBA 9402 present a level and isoenzyme pattern of peroxidases (POD) comparable to nontransformed roots...
  3. Li X, Kushad M. Correlation of glucosinolate content to myrosinase activity in horseradish (Armoracia rusticana). J Agric Food Chem. 2004;52:6950-5 pubmed
    Fully developed horseradish (Armoracia rusticana Gaertn., Mey., & Scherb.) roots from 27 accessions and leaves from a subset of 9 accessions were evaluated for glucosinolates and myrosinase enzyme activity...
  4. Li X, Kushad M. Purification and characterization of myrosinase from horseradish (Armoracia rusticana) roots. Plant Physiol Biochem. 2005;43:503-11 pubmed
    Myrosinase (beta-thioglucoside glucohydrolase; EC from horseradish (Armoracia rusticana) roots was purified to homogeneity by ammonium sulfate fractionation, Q-sepharose, and concanavalin A sepharose affinity chromatography...
  5. Park I, Choi K, Kim D, Choi I, Kim L, Bak W, et al. Fumigant activity of plant essential oils and components from horseradish (Armoracia rusticana), anise (Pimpinella anisum) and garlic (Allium sativum) oils against Lycoriella ingenua (Diptera: Sciaridae). Pest Manag Sci. 2006;62:723-8 pubmed
    ..ingenua. Allyl isothiocyanate was the most toxic, followed by trans-anethole, diallyl disulfide and p-anisaldehyde with LC(50) values of 0.15, 0.20, 0.87 and 1.47 microL L(-1) respectively...
  6. Kozubek E, Irzykowski W, Lehmann P. Genetic and molecular variability of a Turnip mosaic virus population from horseradish (Cochlearia armoracia L.). J Appl Genet. 2007;48:295-306 pubmed
    Variability and genetic structure of a novel Turnip mosaic virus (TuMV) population from horseradish (Cochlearia armoracia L.) were examined...
  7. Lavery C, Macinnis M, MacDonald M, Williams J, Spencer C, Burke A, et al. Purification of peroxidase from Horseradish (Armoracia rusticana) roots. J Agric Food Chem. 2010;58:8471-6 pubmed publisher
    Peroxidase (EC from horseradish ( Armoracia rusticana ) roots was purified using a simple, rapid, three-step procedure: ultrasonication, ammonium sulfate salt precipitation, and hydrophobic interaction chromatography on phenyl ..
  8. Kis M, Burbridge E, Brock I, Heggie L, Dix P, Kavanagh T. An N-terminal peptide extension results in efficient expression, but not secretion, of a synthetic horseradish peroxidase gene in transgenic tobacco. Ann Bot. 2004;93:303-10 pubmed
    Native horseradish (Armoracia rusticana) peroxidase, HRP (EC, isoenzyme C is synthesized with N-terminal and C-terminal peptide extensions, believed to be associated with protein targeting...
  9. Altikatoglu M, Celebi M. Enhanced stability and decolorization of Coomassie Brilliant Blue R-250 by dextran aldehyde-modified horseradish peroxidase. Artif Cells Blood Substit Immobil Biotechnol. 2011;39:185-90 pubmed publisher
    ..In addition, Coomassie Brilliant Blue R-250 was efficiently decolorized using the free and modified HRP. After 5 minutes of treatment, the color removal of dye was 80-90%. Modified HRP showed effective performance compared to free HRP. ..

More Information

Publications122 found, 100 shown here

  1. Kaiser S, Mutters N, Blessing B, Günther F. Natural isothiocyanates express antimicrobial activity against developing and mature biofilms of Pseudomonas aeruginosa. Fitoterapia. 2017;119:57-63 pubmed publisher
    ..of natural isothiocyanates (ITCs) found in plants such as nasturtium (Tropaeolum majus) and horseradish (Armoracia rusticana), and the need of new chemotherapeutic options for treatment of infections caused by multidrug-..
  2. Gregersen N, Belza A, Jensen M, Ritz C, Bitz C, Hels O, et al. Acute effects of mustard, horseradish, black pepper and ginger on energy expenditure, appetite, ad libitum energy intake and energy balance in human subjects. Br J Nutr. 2013;109:556-63 pubmed publisher
    ..Further studies should explore the possible strength and mechanisms of the potential thermogenic effect of mustard actives, and potential enhancement by, for example, combinations with other food components. ..
  3. Agabeili R, Kasimova T. [Antimutagenic activity of Armoracia rusticana, Zea mays and Ficus carica plant extracts and their mixture]. Tsitol Genet. 2005;39:75-9 pubmed
    Antimutagenic action of plant extracts of Armoracia rusticana, Ficus carica, Zea mays and their mixture on environmental xenobiotics has been investigated...
  4. Agneta R, Rivelli A, Ventrella E, Lelario F, Sarli G, Bufo S. Investigation of glucosinolate profile and qualitative aspects in sprouts and roots of horseradish (Armoracia rusticana) using LC-ESI-hybrid linear ion trap with Fourier transform ion cyclotron resonance mass spectrometry and infrared multiphoton dis. J Agric Food Chem. 2012;60:7474-82 pubmed publisher
    Within the family of Brassicaceae, an important source of glucosinolates (GLSs) is represented by horseradish ( Armoracia rusticana P. Gaertner, B...
  5. Marzocco S, Calabrone L, Adesso S, Larocca M, Franceschelli S, Autore G, et al. Anti-inflammatory activity of horseradish (Armoracia rusticana) root extracts in LPS-stimulated macrophages. Food Funct. 2015;6:3778-88 pubmed publisher
    Horseradish (Armoracia rusticana) is a perennial crop belonging to the Brassicaceae family...
  6. Song Y, Xu C, Wei W, Ren J, Qu X. Light regulation of peroxidase activity by spiropyran functionalized carbon nanotubes used for label-free colorimetric detection of lysozyme. Chem Commun (Camb). 2011;47:9083-5 pubmed publisher
    ..This design has been developed for a label-free colorimetric assay of lysozyme with a direct detection limit of 30 nM. ..
  7. Wang L, Zhou Q, Zhao B, Huang X. Toxic effect of heavy metal terbium ion on cell membrane in horseradish. Chemosphere. 2010;80:28-34 pubmed publisher
    ..The effects of Tb(III) mentioned above were aggravated in horseradish treated with 60 mgL(-1) Tb(III) because Tb(III) could enter the horseradish cell. It was a possible cytotoxic mechanism of Tb(III) on horseradish. ..
  8. Huber C, Bartha B, Schroder P. Metabolism of diclofenac in plants--hydroxylation is followed by glucose conjugation. J Hazard Mater. 2012;243:250-6 pubmed publisher
    ..tissues and its metabolic pathway was addressed using Hordeum vulgare (barley) and a hairy root cell culture of Armoracia rusticana (horse radish) as model species...
  9. Weil M, Zhang Y, Nair M. Tumor cell proliferation and cyclooxygenase inhibitory constituents in horseradish (Armoracia rusticana) and Wasabi (Wasabia japonica). J Agric Food Chem. 2005;53:1440-4 pubmed
    Cyclooxygenase and human tumor cell growth inhibitory extracts of horseradish (Armoracia rusticana) and wasabi (Wasabia japonica) rhizomes upon purification yielded active compounds 1-3 from horseradish and 4 and 5 from wasabi rhizomes...
  10. Goos K, Albrecht U, Schneider B. [Efficacy and safety profile of a herbal drug containing nasturtium herb and horseradish root in acute sinusitis, acute bronchitis and acute urinary tract infection in comparison with other treatments in the daily practice/results of a prospective co. Arzneimittelforschung. 2006;56:249-57 pubmed
    ..Primary efficacy criterion was the change of the complaints quantified by the change of the relative symptom score averaged over all symptoms and related to the baseline value...
  11. Zhang X, Wang L, Zhou A, Zhou Q, Huang X. Alterations in cytosol free calcium in horseradish roots simultaneously exposed to lanthanum(III) and acid rain. Ecotoxicol Environ Saf. 2016;126:62-70 pubmed publisher
    ..A low concentration of La(III) (20 mg L(-1)) could alleviate the adverse effects on the roots caused by acid rain, and the combined exposures at higher concentrations of La(III) and acid rain had synergic effects on the roots. ..
  12. Yang X, Guo Y, Mei Z. Chemiluminescent determination of H2O2 using 4-(1,2,4-triazol-1-yl)phenol as an enhancer based on the immobilization of horseradish peroxidase onto magnetic beads. Anal Biochem. 2009;393:56-61 pubmed publisher
    ..The linear range for H(2)O(2) was 2.0x10(-6) to 1.0x10(-3) M. The detection limit for H(2)O(2) was 2.0x10(-6) M. The proposed sensor was applied successfully to the determination of H(2)O(2) in rainwater. ..
  13. MacCuspie R, Gorka D. Refining the statistical model for quantitative immunostaining of surface-functionalized nanoparticles by AFM. Anal Bioanal Chem. 2013;405:8197-206 pubmed publisher
    ..Example AFM data sets, using horseradish peroxidase conjugated to gold nanoparticles, are presented to illustrate how to implement this method successfully. ..
  14. Govere E, Tonegawa M, Bruns M, Wheeler E, Heinemann P, Kephart K, et al. Deodorization of swine manure using minced horseradish roots and peroxides. J Agric Food Chem. 2005;53:4880-9 pubmed
    ..The use of minced horseradish (Armoracia rusticanaL) roots (1:10 w/v plant tissue to swine slurry ratio), with calcium peroxide (CaO2 at 26 or 34 mM) or ..
  15. Uhlik O, Jecna K, Mackova M, Vlcek C, Hroudova M, Demnerova K, et al. Biphenyl-metabolizing bacteria in the rhizosphere of horseradish and bulk soil contaminated by polychlorinated biphenyls as revealed by stable isotope probing. Appl Environ Microbiol. 2009;75:6471-7 pubmed publisher
    ..order to identify members of the microbial community that metabolize biphenyl in the rhizosphere of horseradish (Armoracia rusticana) cultivated in soil contaminated with polychlorinated biphenyls (PCBs) compared to members of the ..
  16. Hoyer H, Schlocker W, Greindl M, Ostermann T, Bernkop Schnurch A. Preparation and evaluation of thiomer nanoparticles via high pressure homogenization. J Microencapsul. 2010;27:487-95 pubmed publisher
    ..The preparation method described here might be a useful tool for a more upscaled production of nanoparticulate drug delivery systems. ..
  17. Lin M, Lu D, Zhu J, Yang C, Zhang Y, Liu Z. Magnetic enzyme nanogel (MENG): a universal synthetic route for biocatalysts. Chem Commun (Camb). 2012;48:3315-7 pubmed publisher
  18. Lu L, Hu Y, Huang X, Qu Y. A bioelectrochemical method for the quantitative description of the Hofmeister effect of ionic liquids in aqueous solution. J Phys Chem B. 2012;116:11075-80 pubmed publisher
  19. Ryan B, Carolan N, Ó Fágáin C. Horseradish and soybean peroxidases: comparable tools for alternative niches?. Trends Biotechnol. 2006;24:355-63 pubmed
    ..It also reviews the current knowledge and applications to date of SBP, particularly biosensors. The final paragraphs speculate on the future of plant heme-based peroxidases, with probable trends outlined and explored. ..
  20. Bilal M, Iqbal H, Hu H, Wang W, Zhang X. Development of horseradish peroxidase-based cross-linked enzyme aggregates and their environmental exploitation for bioremediation purposes. J Environ Manage. 2017;188:137-143 pubmed publisher
    In the present study, horseradish peroxidase (HRP), in-house isolated crude cocktail enzyme, from Armoracia rusticana was cross-linked using a new type of cross-linking agent, i.e...
  21. Kroener E, Buettner A. Unravelling important odorants in horseradish (Armoracia rusticana). Food Chem. 2017;232:455-465 pubmed publisher
    Horseradish (Armoracia rusticana) is a plant well known for its roots' spicy aroma...
  22. Heijnis W, Wierenga P, van Berkel W, Gruppen H. Directing the oligomer size distribution of peroxidase-mediated cross-linked bovine alpha-lactalbumin. J Agric Food Chem. 2010;58:5692-7 pubmed publisher
    ..In conclusion, this study shows that the size distribution of peroxidase-mediated cross-linked alpha-lactalbumin can be directed toward the protein oligomers desired. ..
  23. Macherius A, Seiwert B, Schroder P, Huber C, Lorenz W, Reemtsma T. Identification of plant metabolites of environmental contaminants by UPLC-QToF-MS: the in vitro metabolism of triclosan in horseradish. J Agric Food Chem. 2014;62:1001-9 pubmed publisher
    ..The large number of metabolites detected and identified in this study emphasizes the importance of a comprehensive analytical approach in studies on the uptake and fate of organic contaminants in plants. ..
  24. Šekuljica N, Prlainović N, Jovanović J, Stefanović A, Djokić V, Mijin D, et al. Immobilization of horseradish peroxidase onto kaolin. Bioprocess Biosyst Eng. 2016;39:461-72 pubmed publisher
    ..The obtained kinetic parameters and reusability study confirmed improvement in performances of k-HRP compared to free, indicating that k-HRP has a great potential for environmental purposes. ..
  25. Lu S, Wang X, Lu Q, Hu X, Uppal N, Omenetto F, et al. Stabilization of enzymes in silk films. Biomacromolecules. 2009;10:1032-42 pubmed publisher
  26. Ng Y, di Lena F, Chai C. PolyPEGA with predetermined molecular weights from enzyme-mediated radical polymerization in water. Chem Commun (Camb). 2011;47:6464-6 pubmed publisher
    ..The mechanism of polymerization resembles an ARGET ATRP process. ..
  27. Wang L, Zhou Q, Lu T, Ding X, Huang X. Molecular and cellular mechanism of the effect of La(III) on horseradish peroxidase. J Biol Inorg Chem. 2010;15:1063-9 pubmed publisher
    ..It is suggested that the accumulation of La in the environment, especially the formation of the La-HRP complex in vivo, is harmful to organisms...
  28. Hasumura M, Imai T, Cho Y, Ueda M, Hirose M, Nishikawa A, et al. Toxic effects of a horseradish extract and allyl isothiocyanate in the urinary bladder after 13-week administration in drinking water to F344 rats. J Toxicol Sci. 2011;36:763-74 pubmed
    ..4 and 8.0 mg/kg body weight/day, respectively, and there appeared to be comparable toxicological properties of HRE to AITC, such as the inductive effect of significant proliferative lesions in the urinary bladder. ..
  29. Möller M, Hatch D, Kim H, Porter N. Superoxide reaction with tyrosyl radicals generates para-hydroperoxy and para-hydroxy derivatives of tyrosine. J Am Chem Soc. 2012;134:16773-80 pubmed publisher
    ..The para-OOH and para-OH derivatives are much more reactive than other tyrosine oxidation products and may play important roles in physiology and disease. ..
  30. Saricay Y, Dhayal S, Wierenga P, de Vries R. Protein cluster formation during enzymatic cross-linking of globular proteins. Faraday Discuss. 2012;158:51-63; discussion 105-24 pubmed
    ..Consistent with this two-step mechanism, atomic force microscopy shows that the covalent protein clusters are very heterogeneous and seem to consist of smaller subclusters. ..
  31. Maczka W, Mironowicz A. Biotransformation of isoprenoids and shikimic acid derivatives by a vegetable enzymatic system. Z Naturforsch C. 2004;59:201-4 pubmed
    ..celeriac (Apium graveolens L. var. rapaceum) and horse-radish (Armoracia lapathifolia Gilib.) hydrolyzed the ester bonds of acetates of phenols or alicyclic alcohols...
  32. Kumar D, de Visser S, Sharma P, Hirao H, Shaik S. Sulfoxidation mechanisms catalyzed by cytochrome P450 and horseradish peroxidase models: spin selection induced by the ligand. Biochemistry. 2005;44:8148-58 pubmed
    ..S., Rock, D. A., Rock, D. A., Jones, J. P. (2004) J. Am. Chem. Soc. 126, 8868-8869]. Theory shows that intrinsically, HRP should be as reactive as P450 toward sulfoxidation. ..
  33. Derat E, Shaik S, Rovira C, Vidossich P, Alfonso Prieto M. The effect of a water molecule on the mechanism of formation of compound 0 in horseradish peroxidase. J Am Chem Soc. 2007;129:6346-7 pubmed
  34. Oxford J, Lambkin R, Guralnik M, Rosenbloom R, Petteruti M, Digian K, et al. In vivo prophylactic activity of QR-435 against H3N2 influenza virus infection. Am J Ther. 2007;14:462-8 pubmed
    ..QR-435 is effective for both prevention of H3N2 viral transmission and prophylaxis. These preclinical results warrant further evaluation of its prophylactic properties against avian influenza virus infection in humans. ..
  35. Alnsour M, Kleinwächter M, Böhme J, Selmar D. Sulfate determines the glucosinolate concentration of horseradish in vitro plants (Armoracia rusticana Gaertn., Mey. & Scherb.). J Sci Food Agric. 2013;93:918-23 pubmed publisher
    Horseradish plants (Armoracia rusticana) contain high concentrations of glucosinolates. Former studies have revealed that Armoracia plants cultivated in vitro have markedly lower glucosinolate concentrations than those grown in soils...
  36. Sauvêtre A, May R, Harpaintner R, Poschenrieder C, Schroder P. Metabolism of carbamazepine in plant roots and endophytic rhizobacteria isolated from Phragmites australis. J Hazard Mater. 2018;342:85-95 pubmed publisher
    ..In this work, a horseradish (Armoracia rusticana) hairy root (HR) culture has been used as a plant model to study the interactions between roots and ..
  37. Govere E, Tonegawa M, Bruns M, Wheeler E, Kephart K, Voigt J, et al. Using minced horseradish roots and peroxides for the deodorization of swine manure: a pilot scale study. Bioresour Technol. 2007;98:1191-8 pubmed
    ..This pilot scale (20-120 L) study tested the use of minced horseradish (Armoracia rusticana L...
  38. Davydov R, Osborne R, Kim S, Dawson J, Hoffman B. EPR and ENDOR studies of cryoreduced compounds II of peroxidases and myoglobin. Proton-coupled electron transfer and protonation status of ferryl hemes. Biochemistry. 2008;47:5147-55 pubmed publisher
    ..The data also indicate that Mb and HRP compounds II exist as two major conformational substates. ..
  39. Wu H, Zhang G, Zeng S, Lin K. Extraction of allyl isothiocyanate from horseradish (Armoracia rusticana) and its fumigant insecticidal activity on four stored-product pests of paddy. Pest Manag Sci. 2009;65:1003-8 pubmed publisher
    Isothiocyanates (ITCs) extracted from Armoracia rusticana Gaertn., May & Scherb. have been shown previously to have insecticidal activity...
  40. Chen Q, Chen M, Zhou J, Han Q, Wang Y, Fu Y. The application of chiral arginine and multi-walled carbon nanotubes as matrices to monitor hydrogen peroxide. Bioelectrochemistry. 2013;91:32-6 pubmed publisher
    ..9×10(-2)M and a detection limit of 2×10(-5)M (S/N=3). For the case of DAM-CS@HRP/dpAu/GCE, there has a linear relationship with the concentration of H2O2 from 1.8×10(-5) to 2.6×10(-3)M and the detection limit is 6×10(-5)M (S/N=3). ..
  41. Matsuda H, Ochi M, Nagatomo A, Yoshikawa M. Effects of allyl isothiocyanate from horseradish on several experimental gastric lesions in rats. Eur J Pharmacol. 2007;561:172-81 pubmed
    ..These findings suggest that endogenous prostaglandins play an important role in the protective effect of allyl isothiocyanate in ethanol-induced gastric lesions different from capsaicin, piperine, and omeprazole. ..
  42. Ye Y, Wang L, Huang X, Lu T, Ding X, Zhou Q, et al. Subcellular location of horseradish peroxidase in horseradish leaves treated with La(III), Ce(III) and Tb(III). Ecotoxicol Environ Saf. 2008;71:677-84 pubmed publisher
    ..This also indicated that REEs ions may regulate the plant growth through changing the distribution of enzymes. ..
  43. Sennepin A, Charpentier S, Normand T, Sarré C, Legrand A, Mollet L. Multiple reprobing of Western blots after inactivation of peroxidase activity by its substrate, hydrogen peroxide. Anal Biochem. 2009;393:129-31 pubmed publisher
    ..A 15-min incubation allows one to perform at least five different sequential detections without losing significant amounts of blotted proteins. ..
  44. Liu X, Zhang J, Yan R, Zhang Q, Liu X. Preparation of graphene nanoplatelet-titanate nanotube composite and its advantages over the two single components as biosensor immobilization materials. Biosens Bioelectron. 2014;51:76-81 pubmed publisher
    ..The precision and stability study provided additional evidence for the feasibility of using GNP-TNT composite as electrode modification material. ..
  45. Tonegawa M, Dec J, Bollag J. Use of additives to enhance the removal of phenols from water treated with horseradish and hydrogen peroxide. J Environ Qual. 2003;32:1222-7 pubmed
    ..were used to facilitate the removal of 2,4-dichlorophenol (2,4-DCP) from water using minced horseradish (Armoracia rusticana P. Gaertn. et al.) as a carrier of peroxidase activity...
  46. McDonald A, Tipton K. Computer-controlled system for the study of oxidase reactions: application to the peroxidase-oxidase oscillator. J Phys Chem B. 2010;114:16244-52 pubmed publisher
    ..For peroxidase from horseradish, the optimal pH for oscillatory behavior was found to be in the range 4.5-5.5. ..
  47. Moniruzzaman M, Goto M. Molecular assembly-assisted biocatalytic reactions in ionic liquids. Methods Mol Biol. 2011;743:37-49 pubmed publisher
    ..A detailed description of the procedure for the potential use of this newly developed water-in-IL reverse microemulsion for biocatalysis is also included. ..
  48. Skarpeli Liati M, Pati S, Bolotin J, Eustis S, Hofstetter T. Carbon, hydrogen, and nitrogen isotope fractionation associated with oxidative transformation of substituted aromatic N-alkyl amines. Environ Sci Technol. 2012;46:7189-98 pubmed publisher
  49. Liu J, Yang B, Chen C. A novel membrane-based process to isolate peroxidase from horseradish roots: optimization of operating parameters. Bioprocess Biosyst Eng. 2013;36:251-7 pubmed publisher
    The optimization of operating parameters for the isolation of peroxidase from horseradish (Armoracia rusticana) roots with ultrafiltration (UF) technology was systemically studied...
  50. Olsen C, Huang X, Hansen C, Cipollini D, Ørgaard M, Matthes A, et al. Glucosinolate diversity within a phylogenetic framework of the tribe Cardamineae (Brassicaceae) unraveled with HPLC-MS/MS and NMR-based analytical distinction of 70 desulfoglucosinolates. Phytochemistry. 2016;132:33-56 pubmed publisher
    ..19 and 16 individual glucosinolates, respectively), comparable to total diversity in literature reports of Armoracia rusticana (17?), Barbarea vulgaris (20-24), and Rorippa indica (>20?)...
  51. Bilal M, Rasheed T, Iqbal H, Hu H, Wang W, Zhang X. Novel characteristics of horseradish peroxidase immobilized onto the polyvinyl alcohol-alginate beads and its methyl orange degradation potential. Int J Biol Macromol. 2017;105:328-335 pubmed publisher
    Herein, we report the immobilization of in-house isolated horseradish peroxidase (HRP) from Armoracia rusticana with novel characteristics...
  52. Bezsudnova E, Zherdev A, Ermolenko D, Iakovleva I, Sviridov V, Popov V, et al. [Peroxidase refolding in the presence of specific antibodies]. Prikl Biokhim Mikrobiol. 2003;39:509-17 pubmed
    ..5 to 1.7 times in the presence of antibody H1. Effects of the antibodies constituting the panel on the activity of native peroxidase and the stability of its dilute solutions were analyzed. ..
  53. Conrad A, Kolberg T, Engels I, Frank U. [In vitro study to evaluate the antibacterial activity of a combination of the haulm of nasturtium (Tropaeoli majoris herba) and of the roots of horseradish (Armoraciae rusticanae radix)]. Arzneimittelforschung. 2006;56:842-9 pubmed
    ..The active ingredients are volatile mustard oils, which are activated in the gastrointestinal tract after oral intake. Previous research has shown mustard oils derived from either N or H to possess antibacterial activity...
  54. Matsui T, Tabayashi A, Iwano M, Shinmyo A, Kato K, Nakayama H. Activity of the C-terminal-dependent vacuolar sorting signal of horseradish peroxidase C1a is enhanced by its secondary structure. Plant Cell Physiol. 2011;52:413-20 pubmed publisher
    ..analyzed regulatory mechanisms of vacuolar sorting of a model vacuole-type PRX, the C1a isozyme of horseradish (Armoracia rusticana) (HRP C1a)...
  55. Wang Z, Liu F, Lu C. Chemiluminescence flow biosensor for glucose using Mg-Al carbonate layered double hydroxides as catalysts and buffer solutions. Biosens Bioelectron. 2012;38:284-8 pubmed publisher
    ..The success of this work has broken the bottleneck of the pH incompatibility between luminol CL and enzyme activity. ..
  56. Delfino I, Manzoni C, Sato K, Dennison C, Cerullo G, Cannistraro S. Ultrafast pump-probe study of excited-state charge-transfer dynamics in umecyanin from horseradish root. J Phys Chem B. 2006;110:17252-9 pubmed
    ..Finally, the Fourier transform of the oscillatory component of the signal presents additional bands in the low-frequency region which are assigned to collective motions of the protein. ..
  57. Munoz J, Garcia Molina F, Varon R, Rodriguez Lopez J, Garcia Ruíz P, Garcia Canovas F, et al. Kinetic characterization of the oxidation of chlorogenic acid by polyphenol oxidase and peroxidase. Characteristics of the o-quinone. J Agric Food Chem. 2007;55:920-8 pubmed
    ..The kinetic constants of mushroom PPO and horseradish POD are determined. ..
  58. Conrad A, Biehler D, Nobis T, Richter H, Engels I, Biehler K, et al. Broad spectrum antibacterial activity of a mixture of isothiocyanates from nasturtium (Tropaeoli majoris herba) and horseradish (Armoraciae rusticanae radix). Drug Res (Stuttg). 2013;63:65-8 pubmed publisher
    ..Low susceptibilities were determined for viridans streptococci and enterococci. Interestingly, both resistant and non-resistant bacteria were similarly susceptible to the test preparation...
  59. Dennison C, Harrison M. The active-site structure of umecyanin, the stellacyanin from horseradish roots. J Am Chem Soc. 2004;126:2481-9 pubmed
  60. Guo X, Zhou Q, Lu T, Fang M, Huang X. Distribution and Translocation of 141Ce (III) in Horseradish. Ann Bot. 2007;100:1459-65 pubmed
    ..The distribution and translocation of (141)Ce (III) in horseradish was investigated in order to help understand the biochemical behaviour and toxic mechanism of REEs in plants...
  61. Guo S, Zhou Q, Lu T, Ding X, Huang X. Spectroscopic studies of interactions involving horseradish peroxidase and Tb3+. Spectrochim Acta A Mol Biomol Spectrosc. 2008;70:818-23 pubmed
    ..This study would provide some references for better understanding the rare earth elements and heavy metals on peroxidase toxicity in living organisms...
  62. Supek F, Peharec P, Krsnik Rasol M, Smuc T. Enhanced analytical power of SDS-PAGE using machine learning algorithms. Proteomics. 2008;8:28-31 pubmed
  63. Szatkowski L, Thompson M, Kaminski R, Franzen S, Dybala Defratyka A. Oxidative dechlorination of halogenated phenols catalyzed by two distinct enzymes: Horseradish peroxidase and dehaloperoxidase. Arch Biochem Biophys. 2011;505:22-32 pubmed publisher
  64. Yun Y, Kim H, Kim J, Hwang K, Ahn Y. Contact and fumigant toxicity of Armoracia rusticana essential oil, allyl isothiocyanate and related compounds to Dermatophagoides farinae. Pest Manag Sci. 2012;68:788-94 pubmed publisher
    The toxicity to adult Dermatophagoides farinae of allyl isothiocyanate identified in horseradish, Armoracia rusticana, oil and another 27 organic isothiocyanates was evaluated using contact + fumigant and vapour-phase mortality bioassays...
  65. Guthals A, Clauser K, Frank A, Bandeira N. Sequencing-grade de novo analysis of MS/MS triplets (CID/HCD/ETD) from overlapping peptides. J Proteome Res. 2013;12:2846-57 pubmed publisher
    ..Using these strategies, we show that triplet CID/HCD/ETD MS/MS spectra from overlapping peptides yield de novo sequences of average length 70 AA and as long as 200 AA at up to 99% sequencing accuracy...
  66. Chen F, Huber C, May R, Schröder P. Metabolism of oxybenzone in a hairy root culture: Perspectives for phytoremediation of a widely used sunscreen agent. J Hazard Mater. 2016;306:230-236 pubmed publisher
    ..the potential degradation capacity of plants for OBZ in phytotreatment, a well-established hairy root culture (Armoracia rusticana) was treated with OBZ...
  67. Dekić M, Radulović N, Stojanović N, Randjelović P, Stojanović Radić Z, Najman S, et al. Spasmolytic, antimicrobial and cytotoxic activities of 5-phenylpentyl isothiocyanate, a new glucosinolate autolysis product from horseradish (Armoracia rusticana P. Gaertn., B. Mey. & Scherb., Brassicaceae). Food Chem. 2017;232:329-339 pubmed publisher
    ..A non-selective antimicrobial activity of all ITCs was revealed in the case of 6 bacterial and 2 fungal strains. ..
  68. Pellicer J, Gómez López V. Pulsed light inactivation of horseradish peroxidase and associated structural changes. Food Chem. 2017;237:632-637 pubmed publisher
    ..The study indicates that the inactivation of POD by PL is an all-or-none process related to loss of helical structure, weak unfolding and ejection of the prostetic group. ..
  69. Laberge M, Szigeti K, Fidy J. The charge transfer band in horseradish peroxidase correlates with heme in-plane distortions induced by calcium removal. Biopolymers. 2004;74:41-5 pubmed
    ..200 and 0.134 A for the Ca(2+)-depleted species. Our NSD results corroborate the role proposed for the protein matrix, namely to fine-tune the active site by inducing subtle changes in heme planarity and spin state of the iron...
  70. Ingledew W, Rich P. A study of the horseradish peroxidase catalytic site by FTIR spectroscopy. Biochem Soc Trans. 2005;33:886-9 pubmed
    ..Concomitant with the photolysis of the CO ligand are changes due to haem and protein vibrations, predominant among which are arginine and histidine residue vibrations...
  71. Nakamura R, Matsushita Y, Umemoto K, Usuki A, Fukushima K. Enzymatic polymerization of coniferyl alcohol in the presence of cyclodextrins. Biomacromolecules. 2006;7:1929-34 pubmed
    ..The 8-O-4' structure in DHP prepared in the presence of alpha-cyclodextrin had racemic form as shown by ozonation...
  72. Meyer F, Eustachi A. [From nasal irrigation to horseradish poultice. Prescriptions for nasal congestion (interview by Dr. Judith Neumaier)]. MMW Fortschr Med. 2007;149:6 pubmed
  73. Guo S, Cao R, Lu A, Zhou Q, Lu T, Ding X, et al. One of the possible mechanisms for the inhibition effect of Tb(III) on peroxidase activity in horseradish (Armoracia rusticana) treated with Tb(III). J Biol Inorg Chem. 2008;13:587-97 pubmed publisher
    One of the possible mechanisms for the inhibition effect of Tb(III) on peroxidase activity in horseradish (Armoracia rusticana) treated with Tb(III) was investigated using some biophysical and biochemical methods...
  74. Huang Y, Wang W, Li Z, Qin X, Bu L, Tang Z, et al. Horseradish peroxidase-catalyzed synthesis of poly(thiophene-3-boronic acid) biocomposites for mono-/bi-enzyme immobilization and amperometric biosensing. Biosens Bioelectron. 2013;44:41-7 pubmed publisher
  75. Johnson E, Chen L, Kubiak P, McDonald S, Adams D, Cameron P. Surface nucleated growth of dipeptide fibres. Chem Commun (Camb). 2013;49:8698-700 pubmed publisher
    ..Placing the seeding-layer in contact with dipeptide led to growth of fibres overnight. Active enzymes were incorporated into the gel by adding them to the growth solution. ..
  76. Wang H, Zhang M, Lv Q, Yue N, Gong B. Determination of berberine and the study of fluorescence quenching mechanism between berberine and enzyme-catalyzed product. Spectrochim Acta A Mol Biomol Spectrosc. 2009;73:682-6 pubmed publisher
    ..3 J K(-1) mol(-1) and the mean value DeltaG = -39.65 kJ mol(-1) were estimated which showed that the reaction was spontaneous and endothermic. The main binding force was hydrophobic force because both DeltaH and DeltaS were positive...
  77. Takahashi S, Masuda T. High throughput heme assay by detection of chemiluminescence of reconstituted horseradish peroxidase. Comb Chem High Throughput Screen. 2009;12:532-5 pubmed
    ..This assay is sensitive, quick, provides a large dynamic range, and is well suited for large-scale analysis of heme extracted from minute amount of samples...
  78. Matsuo T, Hayashi A, Abe M, Matsuda T, Hisaeda Y, Hayashi T. Meso-unsubstituted iron corrole in hemoproteins: remarkable differences in effects on peroxidase activities between myoglobin and horseradish peroxidase. J Am Chem Soc. 2009;131:15124-5 pubmed publisher
    ..This finding can be attributed to the difference in the oxidation states of the corrole iron when these proteins are in the resting state...
  79. Yao H, Hu N. Triply responsive films in bioelectrocatalysis with a binary architecture: combined layer-by-layer assembly and hydrogel polymerization. J Phys Chem B. 2011;115:6691-9 pubmed publisher
    ..This film system with the unique binary architecture may establish a foundation for fabricating a novel type of multicontrollable biosensors based on bioelectrocatalysis with immobilized enzymes...
  80. Kazakova L, Shabarchina L, Anastasova S, Pavlov A, Vadgama P, Skirtach A, et al. Chemosensors and biosensors based on polyelectrolyte microcapsules containing fluorescent dyes and enzymes. Anal Bioanal Chem. 2013;405:1559-68 pubmed publisher
    ..Because internalization of the micron-sized multi-component capsules was feasible, they could be further optimized for in-situ intracellular sensing and metabolite monitoring on the basis of fluorescence reporting...
  81. Yang G, Sun Z, Lv X, Deng Y, Zhou Q, Huang X. Living target of Ce(III) action on horseradish cells: proteins on/in cell membrane. Biol Trace Elem Res. 2012;150:396-402 pubmed publisher
    ..The results would provide some references for understanding the cellular effect mechanisms of REEs on plants...
  82. Vig K, Verdyck P. Data on the host plant selection of the horseradish flea beetle, Phyllotreta armoraciae (Koch, 1803) (Coleoptera, Chrysomelidae, Alticinae). Meded Rijksuniv Gent Fak Landbouwkd Toegep Biol Wet. 2001;66:277-83 pubmed
    ..Phyllotreta armoraciae (Koch, 1803) is considered as a monophagous species feeding only on horseradish (Armoracia lapathifolia Usteri). Ph. armoraciae is in fact not monophagous under laboratory conditions...
  83. Koch M, Velarde M, Harrison M, Echt S, Fischer M, Messerschmidt A, et al. Crystal structures of oxidized and reduced stellacyanin from horseradish roots. J Am Chem Soc. 2005;127:158-66 pubmed
  84. Albrecht U, Goos K, Schneider B. A randomised, double-blind, placebo-controlled trial of a herbal medicinal product containing Tropaeoli majoris herba (Nasturtium) and Armoraciae rusticanae radix (Horseradish) for the prophylactic treatment of patients with chronically recurrent low. Curr Med Res Opin. 2007;23:2415-22 pubmed
  85. Wang L, Huang X, Zhou Q. Effects of rare earth elements on the distribution of mineral elements and heavy metals in horseradish. Chemosphere. 2008;73:314-9 pubmed publisher
    ..These results demonstrated that the distribution behaviors of mineral elements and heavy metals in horseradish can be affected by the type and concentration of REEs, and the growth period of plant...
  86. Lee K, Saidel G, Penn M. Permeability change of arterial endothelium is an age-dependent function of lesion size in apolipoprotein E-null mice. Am J Physiol Heart Circ Physiol. 2008;295:H2273-9 pubmed publisher
    ..Furthermore, the IEL is not a significant barrier between the intima and tunica media in the atherosclerotic process...
  87. Guo S, Zhou Q, Lu T, Ding X, Huang X. Inhibition mechanism of Tb(III) on horseradish peroxidase activity. Chem Biodivers. 2008;5:2050-9 pubmed publisher
    ..Thus, the conformation change in the HRP molecules can significantly decrease the electrochemical reaction of HRP and its electrocatalytic activity for the reduction of H2O2...
  88. Gholami Borujeni F, Mahvi A, Nasseri S, Faramarzi M, Nabizadeh R, Alimohammadi M. Enzymatic treatment and detoxification of acid orange 7 from textile wastewater. Appl Biochem Biotechnol. 2011;165:1274-84 pubmed publisher
    ..The acute toxicity tests using Daphnia magna exhibited that the enzymatic treatment significantly decreased the toxicity of the dye solution...
  89. Jakobsen T, Bragason S, Phipps R, Christensen L, Van Gennip M, Alhede M, et al. Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa. Appl Environ Microbiol. 2012;78:2410-21 pubmed publisher
    ..Real-time PCR (RT-PCR) and DNA microarray studies showed that iberin specifically blocks expression of QS-regulated genes in P. aeruginosa...
  90. Yang G, Chu Y, Lv X, Zhou Q, Huang X. Interaction between La(III) and proteins on the plasma membrane of horseradish. Spectrochim Acta A Mol Biomol Spectrosc. 2012;92:42-5 pubmed publisher
    ..We demonstrate that the proteins on the plasma membrane are the targets of La(III) action on plant cell...
  91. Park B, Zheng R, Ko K, Cameron B, Yoon D, Kim D. A novel glucose biosensor using bi-enzyme incorporated with peptide nanotubes. Biosens Bioelectron. 2012;38:295-301 pubmed publisher
    ..994. A maximum sensitivity of 0.3 mA M(-1)and reproducibility (RSD) of 1.95% were demonstrated. The PNT-encapsulated enzyme showed its retention of >85% of the initial current response after one month of storage...
  92. Karim Z, Adnan R, Ansari M. Low concentration of silver nanoparticles not only enhances the activity of horseradish peroxidase but alter the structure also. PLoS ONE. 2012;7:e41422 pubmed publisher
    ..Finally, incubation of a plant peroxidase, HRP with Ag-NPs, within the reported concentration range not only enhances the activity but also alter the structure. ..