berberidaceae

Summary

Summary: The Barberry plant family of the order Ranunculales, subclass Magnoliidae, class Magnoliopsida. The shrubs have spiny leaves.

Top Publications

  1. Sun Y, Fung K, Leung P, Shaw P. A phylogenetic analysis of Epimedium (Berberidaceae) based on nuclear ribosomal DNA sequences. Mol Phylogenet Evol. 2005;35:287-91 pubmed
  2. Tsukiyama M, Akaishi T, Ueki T, Okumura H, Abe K. The extract from Nandina domestica THUNBERG inhibits histamine- and serotonin-induced contraction in isolated guinea pig trachea. Biol Pharm Bull. 2007;30:2063-8 pubmed
    ..These results suggest that NDE has inhibitory effects on tracheal smooth muscle contraction, and nantenine cannot account solely for this effect of NDE...
  3. Li Y, Zhai S, Qiu Y, Guo Y, Ge X, Comes H. Glacial survival east and west of the 'Mekong-Salween Divide' in the Himalaya-Hengduan Mountains region as revealed by AFLPs and cpDNA sequence variation in Sinopodophyllum hexandrum (Berberidaceae). Mol Phylogenet Evol. 2011;59:412-24 pubmed publisher
    ..This study thus indicates an important role for mountain glaciers in driving (incipient) allopatric speciation across the MSD in the HHM region by causing vicariant lineage divergence and acting as barriers to post-divergence gene flow...
  4. Li A, Zhu Y, Li X, Tian X. Antimicrobial activity of four species of Berberidaceae. Fitoterapia. 2007;78:379-81 pubmed
    ..Most of the extracts have been proved to be active against Gram(+) bacteria...
  5. Jiang R, Zhou J, Hon P, Li S, Zhou Y, Li L, et al. Lignans from Dysosma versipellis with inhibitory effects on prostate cancer cell lines. J Nat Prod. 2007;70:283-6 pubmed
    ..Thus, cultivation of D. versipellis in suitable locations may serve as an alternative source for podophyllotoxin (2) production...
  6. Sun Y, Moore M, Zhang S, Soltis P, Soltis D, Zhao T, et al. Phylogenomic and structural analyses of 18 complete plastomes across nearly all families of early-diverging eudicots, including an angiosperm-wide analysis of IR gene content evolution. Mol Phylogenet Evol. 2016;96:93-101 pubmed publisher
    ..cuneifolia (Sabiaceae), Sabia yunnanensis (Sabiaceae), Epimedium sagittatum (Berberidaceae), Euptelea pleiosperma (Eupteleaceae), Akebia trifoliata (Lardizabalaceae), Stephania japonica (Menispermaceae)..
  7. Thakur P, Chawla R, Tanwar A, Chakotiya A, Narula A, Goel R, et al. Attenuation of adhesion, quorum sensing and biofilm mediated virulence of carbapenem resistant Escherichia coli by selected natural plant products. Microb Pathog. 2016;92:76-85 pubmed publisher
    ..The findings indicated clearly that B. aristata (Family: Berberidaceae) and C...
  8. Kulkarni R, Lee W, Jang T, Lee J, Kwak S, Park M, et al. Caffeoyl glucosides from Nandina domestica inhibit LPS-induced endothelial inflammatory responses. Bioorg Med Chem Lett. 2015;25:5367-71 pubmed publisher
    ..b>Berberidaceae)...
  9. Khan M, Ahmad M. Traditional preference of Wild Edible Fruits (WEFs) for digestive disorders (DDs) among the indigenous communities of Swat Valley-Pakistan. J Ethnopharmacol. 2015;174:339-54 pubmed publisher
    ..Family Berberidaceae dominated with highest FIV (41) followed by Punicaceae (38), Oxalidaceae (36) and Moraceae (35)...

More Information

Publications81

  1. Yan M, Zhang K, Shi Y, Feng L, Lv L, Li B. Mechanism and pharmacological rescue of berberine-induced hERG channel deficiency. Drug Des Devel Ther. 2015;9:5737-47 pubmed publisher
    Berberine (BBR), an isoquinoline alkaloid mainly isolated from plants of Berberidaceae family, is extensively used to treat gastrointestinal infections in clinics...
  2. Li M, Zhang N, Wang Y, Han T, Jiang Y, Rahman K, et al. Coordinate regulatory osteogenesis effects of icariin, timosaponin B II and ferulic acid from traditional Chinese medicine formulas on UMR-106 osteoblastic cells and osteoblasts in neonatal rat calvaria cultures. J Ethnopharmacol. 2016;185:120-31 pubmed publisher
    ..acid (F) and timosaponin B II (T) derived respectively from the leaf of Epimedium brevicornu Maxim (EBM, Berberidaceae), rhizome of Anemarrhena asphodeloides Bunge (AAB, Liliaceae) and root of Angelica sinensis (Oliv...
  3. Potdar D, Hirwani R, Dhulap S. Phyto-chemical and pharmacological applications of Berberis aristata. Fitoterapia. 2012;83:817-30 pubmed
    ..Berberis aristata - an Indian medicinal plant, which belongs to the family Berberidaceae is an ayurvedic herb used since ancient times...
  4. He J, Mu Q. The medicinal uses of the genus Mahonia in traditional Chinese medicine: An ethnopharmacological, phytochemical and pharmacological review. J Ethnopharmacol. 2015;175:668-83 pubmed publisher
    Plants of the genus Mahonia Nuttall (Berberidaceae) have a long history of medical use in Traditional Chinese Medicine (TCM) for the treatment of a wide range of health disorders, such as tuberculosis, periodontitis, dysentery, ..
  5. Alamgeer -, Chabert P, Akhtar M, Jabeen Q, Delecolle J, Heintz D, et al. Endothelium-independent vasorelaxant effect of a Berberis orthobotrys root extract via inhibition of phosphodiesterases in the porcine coronary artery. Phytomedicine. 2016;23:793-9 pubmed publisher
    Berberis orthobotrys Bien ex Aitch. (Berberidaceae) is a plant indigenous of Pakistan that is locally used for the treatment of hypertension...
  6. Karadeniz A, Alexie G, Greten H, Andersch K, Efferth T. Cytotoxicity of medicinal plants of the West-Canadian Gwich׳in Native Americans towards sensitive and multidrug-resistant cancer cells. J Ethnopharmacol. 2015;168:191-200 pubmed publisher
    ..For instance, podophyllotoxin the active ingredient of Podophyllum peltatum L. (Berberidaceae) used by Native Americans to treat warts led to the development of etoposide and teniposide...
  7. Lee S, Yeon M, Shim J. Conservation implications of the genetic diversity of Gymnospermium microrrhynchum in Korea. Genet Mol Res. 2016;15: pubmed publisher
    Gymnospermium microrrhynchum (Berberidaceae) is an ephemeral perennial herb with a limited distributional range in the Baekdudaegan mountain areas of the Korean Peninsula, and is designated a rare plant by the Korean Forest Service...
  8. Mostacero León J, López Medina S, Yabar H, De La Cruz Castillo J. Preserving Traditional Botanical Knowledge: The Importance of Phytogeographic and Ethnobotanical Inventory of Peruvian Dye Plants. Plants (Basel). 2017;6: pubmed publisher
    ..out due to the number of species: Fabaceae (5), Anacardiaceae (2), Annonaceae (2), Asteraceae (2), Berberidaceae (2), Rosaceae (2), and Solanaceae (2)...
  9. Zhang K, Zeng X, Chen Y, Zhao R, Wang H, Wu J. Therapeutic effects of Qian-Yu decoction and its three extracts on carrageenan-induced chronic prostatitis/chronic pelvic pain syndrome in rats. BMC Complement Altern Med. 2017;17:75 pubmed publisher
    ..Bunge var. mongholicus (Bunge) P.K. Hsiao, Fabaceae ), Herba epimedii (Epimedium brevicornum Maxim., Berberidaceae), Herba leonuri (Leonurus japonicus Houtt., Lamiaceae), Cortex phellodendri (Phellodendron chinense Schneid...
  10. Alamgeer -, Uttra A, Hasan U. Anti-arthritic activity of aqueous-methanolic extract and various fractions of Berberis orthobotrys Bien ex Aitch. BMC Complement Altern Med. 2017;17:371 pubmed publisher
    The roots and stem bark of Berberis orthobotrys (Berberidaceae) have long been used traditionally to treat joint pain. Though, it has not been pharmacologically assessed for rheumatoid arthritis...
  11. Wyka T, Karolewski P, Żytkowiak R, Chmielarz P, Oleksyn J. Whole-plant allocation to storage and defense in juveniles of related evergreen and deciduous shrub species. Tree Physiol. 2016;36:536-47 pubmed publisher
    ..and Berberis vulgaris L. (Berberidaceae), Prunus laurocerasus L. and Prunus serotina Ehrh. (Rosaceae), and Viburnum rhytidophyllum Hemsl...
  12. Su X, Li W, Ma J, Kim Y. Chemical constituents from Epimedium koreanum Nakai and their chemotaxonomic significance. Nat Prod Res. 2017;:1-5 pubmed publisher
    ..This is the first report of compounds 2, 3, 4 and 9 in E. koreanum and of compounds 5 and 7 in the family Berberidaceae. The chemotaxonomic significance of the isolated compounds is discussed.
  13. Ayati S, Fazeli B, Momtazi Borojeni A, Cicero A, Pirro M, Sahebkar A. Regulatory effects of berberine on microRNome in Cancer and other conditions. Crit Rev Oncol Hematol. 2017;116:147-158 pubmed publisher
    Berberine (BBR) is an isoquinoline alkaloid found in different plant families such as Berberidaceae, Ranunculaceae, and Papaveraceae...
  14. Williams S, Linske M, Ward J. Long-Term Effects of Berberis thunbergii (Ranunculales: Berberidaceae) Management on Ixodes scapularis (Acari: Ixodidae) Abundance and Borrelia burgdorferi (Spirochaetales: Spirochaetaceae) Prevalence in Connecticut, USA. Environ Entomol. 2017;46:1329-1338 pubmed publisher
    Japanese barberry (Berberis thunbergii de Candolle; Ranunculales: Berberidaceae) is an exotic invasive shrub that escaped cultivation in the United States and is now permanently established in many eastern and midwestern states...
  15. Wang L, Ci X, Lv H, Wang X, QIN F, Cheng G. Isotetrandrine ameliorates tert-butyl hydroperoxide-induced oxidative stress through upregulation of heme oxygenase-1 expression. Exp Biol Med (Maywood). 2016;241:1568-76 pubmed publisher
    1R, 1'S-isotetrandrine, a naturally occurring plant alkaloid found in Mahonia of Berberidaceae, possesses anti-inflammatory, antibacterial, and antiviral properties, but the antioxidative activity and mechanism action remain unclear...
  16. Kost álová D, Kardosova A, Hajnicka V. Effect of Mahonia aquifolium stem bark crude extract and one of its polysaccharide components on production of IL-8. Fitoterapia. 2001;72:802-6 pubmed
    ..The crude extract partly inhibited the IL-8 spontaneous production after 48-h treatment of the cells, while the polysaccharide was found to be a potent inducer of IL-8 production...
  17. Huang K, Jiang W, Zhao J, Wang C, Liu X, Zhang Z, et al. [Determination of podophyllotoxin and total lignans in Sinopodophyllum emodi]. Zhongguo Zhong Yao Za Zhi. 2012;37:1360-5 pubmed
    ..To determine the content of podophyllotoxin and total lignans in Sinopodophyllum emodi Ying from different areas and evaluate the resource utilization of this endangered medicinal plant...
  18. Zong M, Liu H, Qiu Y, Yang S, Zhao M, Fu C. Genetic diversity and geographic differentiation in the threatened species Dysosma pleiantha in China as revealed by ISSR analysis. Biochem Genet. 2008;46:180-96 pubmed publisher
    ..Low seedling recruitment due to inbreeding, restricted gene flow, and genetic drift are proposed as determinant factors responsible for the low genetic diversity and high genetic differentiation observed...
  19. Wang P, Liu Y, Chen T, Xu W, You J, Liu Y, et al. One-step separation and purification of three lignans and one flavonol from Sinopodophyllum emodi by medium-pressure liquid chromatography and high-speed counter-current chromatography. Phytochem Anal. 2013;24:603-7 pubmed publisher
  20. Tsuchida H, Ohizumi Y. (+)-Nantenine isolated from Nandina domestica Thunb. inhibits adrenergic pressor responses in pithed rats. Eur J Pharmacol. 2003;477:53-8 pubmed
    ..These data suggest that (+)-nantenine has antagonistic activities on alpha1-adrenoceptors, alpha2-adrenoceptors and 5-HT2A receptors in pithed rats...
  21. Luo J, Zhang L, Wan M, He S, Yang Y. [Determination of quercetin and kaempferol in Dysosma plants by RP-HPLC]. Zhongguo Zhong Yao Za Zhi. 2010;35:3021-3 pubmed
    ..To determine quercetin and kaempferol in the plant of genus Dysosma that come from different species, different plant parts or different growing areas, which provide the basis of rational utilization of Dysosma plants...
  22. Liang Z, Zhang J, Zhang X, Li J, Zhang X, Zhao C. Endophytic Fungus from Sinopodophyllum emodi (Wall.) Ying that Produces Podophyllotoxin. J Chromatogr Sci. 2016;54:175-8 pubmed publisher
    ..Ying. The identification of podophyllotoxin was performed using high-performance liquid chromatography and liquid chromatography-mass spectrometry (MS)-MS and confirmed by comparison with authentic standards. ..
  23. Sun Y, Li Z, Chen H, Liu X, Zhou W, Hua H. Three new cytotoxic aryltetralin lignans from Sinopodophyllum emodi. Bioorg Med Chem Lett. 2011;21:3794-7 pubmed publisher
    ..However, this needs to be systematically verified by extensive pharmacological experiments...
  24. Xiao P, Wang Y, Chen H. [Some research clues on Chinese herbal medicine for SARS prevention and treatment]. Zhongguo Zhong Yao Za Zhi. 2003;28:481-3 pubmed
    ..To provide some research clues from Chinese herbal medicine for SARS prevention and treatment...
  25. Wang Q, Guo S, Yang X, Zhang Y, Shang M, Shang Y, et al. Flavonoids isolated from Sinopodophylli Fructus and their bioactivities against human breast cancer cells. Chin J Nat Med. 2017;15:225-233 pubmed publisher
  26. Xiao M, Li Q, Guo L, Luo T, Duan W, He W, et al. AFLP analysis of genetic diversity of the endangered species Sinopodophyllum hexandrum in the Tibetan region of Sichuan Province, China. Biochem Genet. 2006;44:47-60 pubmed
    ..On the basis of the genetic and ecological information, we propose some appropriate strategies for conserving the endangered S. hexandrum in this region...
  27. Sun Y, Li Z, Chen H, Zhou W, Hua H. [Study on chemical constituents from the roots and rhizomes of Sinopodophyllum emodi]. Zhong Yao Cai. 2012;35:1607-9 pubmed
    ..To investigate the chemical constituents in the roots and rhizomes of Sinopodophyllum emodi...
  28. Guan B, Gong X, Zhou S. Development and characterization of polymorphic microsatellite markers in Dysosma pleiantha (Berberidaceae). Am J Bot. 2011;98:e210-2 pubmed publisher
    ..The development of compound microsatellite markers was conducted in Dysosma pleiantha to investigate genetic diversity and population genetic structure of this threatened medicinal plant...
  29. Wang A, Liu G, Xu F, Shang M, Cai S. [Research on chemical fingerprint chromatograms of Sinopodophyllum hexandrum]. Zhongguo Zhong Yao Za Zhi. 2013;38:3528-33 pubmed
    ..hexandrum, and provide scientific evidence for clinical application and quality control...
  30. Jhoo J, Sang S, He K, Cheng X, Zhu N, Stark R, et al. Characterization of the triterpene saponins of the roots and rhizomes of blue cohosh (Caulophyllum thalictroides). J Agric Food Chem. 2001;49:5969-74 pubmed
    ..All seven compounds were identified in this species for the first time...
  31. Iwasa K, Cui W, Takahashi T, Nishiyama Y, Kamigauchi M, Koyama J, et al. Biotransformation of phenolic tetrahydroprotoberberines in plant cell cultures followed by LC-NMR, LC-MS, and LC-CD. J Nat Prod. 2010;73:115-22 pubmed publisher
    ..cordata and C. ochotensis var. raddeana, which was distinct from O-methylation in N. domestica, in which 7 was O-methylated at both C-11 and C-10. Stereoselective O-demethylation [(S)-5 to (S)-18] occurred in N. domestica...
  32. Ronse DE Craene L. Floral development of Berberidopsis corallina: a crucial link in the evolution of flowers in the core Eudicots. Ann Bot. 2004;94:741-51 pubmed
    ..It lies at the transition of trimerous or dimerous, simplified apetalous forms into pentamerous, petaliferous flowers...
  33. Sun Y, Gao M, Zhang Y, Wang J, Wu Y, Wang Y, et al. Labdane Diterpenes from the Fruits of Sinopodophyllum emodi. Molecules. 2016;21:434 pubmed publisher
    ..The cytotoxic activities of all isolated compounds were evaluated in comparison with 5-fluorouracil against the MCF-7 and HepG2 cell lines, towards which 3 showed more potent cytotoxicity. ..
  34. Gong W, Fu C, Luo Y, Qiu Y. Molecular identification of Sinopodophyllum hexandrum and Dysosma species using cpDNA sequences and PCR-RFLP markers. Planta Med. 2006;72:650-2 pubmed
    ..Our results suggest that both chloroplast intergenic regions can be used for the identification of S. hexandrum and Dysosma Rhizoma medicines on the market...
  35. Li J, Sun H, Jin L, Cao W, Zhang J, Guo C, et al. Alleviation of podophyllotoxin toxicity using coexisting flavonoids from Dysosma versipellis. PLoS ONE. 2013;8:e72099 pubmed publisher
  36. Zhang L, Li Q, Chen C, Li X, Li M, Hu J, et al. Propioniciclava sinopodophylli sp. nov., isolated from leaves of Sinopodophyllum hexandrum (Royle) Ying. Int J Syst Evol Microbiol. 2017;67:4111-4115 pubmed publisher
    ..nov. is proposed. The type strain is TEYR-7T (=CCTCC?AB 2015257T=KCTC 33808T)...
  37. Yang Z, Liu X, Wang K, Cao X, Wu S. Novel linear and step-gradient counter-current chromatography for bio-guided isolation and purification of cytotoxic podophyllotoxins from Dysosma versipellis (Hance). J Sep Sci. 2013;36:1022-8 pubmed publisher
    ..All components showed potent anticancer activity against human hepatoma cells HepG2...
  38. Zhang M, Shi D. [Determination of podophyllotoxin lignans in Dysosma and its allied plants]. Zhong Yao Cai. 2001;24:411-3 pubmed
    ..The total lignans content is 2%-7%, and there is a big variation between different species. The total lignans content of Dysosma versipellis is related to the habitat...
  39. Sun Y, Li Z, Chen H, Liu X, Zhou W, Hua H. Four new cytotoxic tetrahydrofuranoid lignans from Sinopodophyllum emodi. Planta Med. 2012;78:480-4 pubmed publisher
    ..The cytotoxic activities of all isolated compounds were evaluated against HeLa and KB cell lines, and compound 1 showed the most potent cytotoxicity with IC?? values of 9.7 µM and 4.7 µM, respectively...
  40. Tsukiyama M, Ueki T, Yasuda Y, Kikuchi H, Akaishi T, Okumura H, et al. Beta2-adrenoceptor-mediated tracheal relaxation induced by higenamine from Nandina domestica Thunberg. Planta Med. 2009;75:1393-9 pubmed publisher
    The fruit of Nandina domestica Thunberg (ND, Berberidaceae) has been used to improve cough and breathing difficulties in Japan for many years, but very little is known about the constituent of ND responsible for this effect...
  41. Xia Q, Xu D, Huang Z, Liu J, Wang X, Wang X, et al. Preparation of icariside II from icariin by enzymatic hydrolysis method. Fitoterapia. 2010;81:437-42 pubmed publisher
    ..0), the ratio of icariin/enzyme is 1:1 and reaction time 5 h. By using this enzymatic condition, 95.5 mg icariside II (with the purity of 99.1%) was obtained eventually by transforming 200 mg icariin...
  42. Kodai T, Horiuchi Y, Nishioka Y, Noda N. Novel cycloartane-type triterpenoid from the fruits of Nandina domestica. J Nat Med. 2010;64:216-8 pubmed publisher
    A novel cycloartane-type triterpenoid was isolated from the fruits of Nandina domestica (Berberidaceae). The structure was characterized as 24-methylene-3-oxocycloartane 13-carboxylic acid on the basis of NMR spectroscopic data.
  43. Qiu Y, Guan B, Fu C, Comes H. Did glacials and/or interglacials promote allopatric incipient speciation in East Asian temperate plants? Phylogeographic and coalescent analyses on refugial isolation and divergence in Dysosma versipellis. Mol Phylogenet Evol. 2009;51:281-93 pubmed
    ..As such, D. versipellis accords with the premise that Late Quaternary refugial isolation is likely to have enhanced allopatric (incipient) species formation of temperate plants in East Asia...
  44. Zhang M, Shi D. [The descriptions and microscopy identification of three allied species of Dysosma versipellis]. Zhong Yao Cai. 2001;24:89-92 pubmed
    ..The descriptions, histological and microscopical characteristics of three allied species of Dysosma versipellis were described...
  45. Ma S, Jiang H, Huang H. [A primary study on seed production of medicinal plant Sinopodophyllum hexandrum]. Ying Yong Sheng Tai Xue Bao. 2001;12:363-8 pubmed
    The study on the seed production of five Sinopodophyllum hexandrum (Berberidaceae) populations demonstrated that the average ovule number, average seed number and seed set ratio of these populations were varied, but all positively ..
  46. Masuda T, Fujita N, Odaka Y, Takeda Y, Yonemori S, Nakamoto K, et al. Tyrosinase inhibitory activity of ethanol extracts from medicinal and edible plants cultivated in okinawa and identification of a water-soluble inhibitor from the leaves of Nandina domestica. Biosci Biotechnol Biochem. 2007;71:2316-20 pubmed
    ..Although it was a known compound (4-beta-D-glucopyranosyloxybenzoic acid), its inhibitory activity toward tyrosinase is revealed for the first time in this work...
  47. Iwasa K, Takahashi T, Nishiyama Y, Moriyasu M, Sugiura M, Takeuchi A, et al. Online structural elucidation of alkaloids and other constituents in crude extracts and cultured cells of Nandina domestica by combination of LC-MS/MS, LC-NMR, and LC-CD analyses. J Nat Prod. 2008;71:1376-85 pubmed publisher
    ..Known jatrorrhizine, palmatine, and berberine and unknown (R)-carnegine and (E, E)-, (E, Z)-, and (Z, Z)-terrestribisamide were identified in the callus of N. domestica...
  48. Ueki T, Akaishi T, Okumura H, Abe K. Extract from Nandina domestica inhibits lipopolysaccharide-induced cyclooxygenase-2 expression in human pulmonary epithelial A549 cells. Biol Pharm Bull. 2012;35:1041-7 pubmed
    ..These results suggest that constituent(s) present in water fraction is required but not sufficient for the anti-inflammatory activity of NDE, which may result from interactions among multiple constituents...
  49. Tabatadze N, Bun S, Tabidze B, Mshvildadze V, Dekanosidze G, Ollivier E, et al. New triterpenoid saponins from Leontice smirnowii. Fitoterapia. 2010;81:897-901 pubmed publisher
    ..The aglycone 3?-hydroxy-30-norolean-12,20(29)-dien-28-oic acid was observed for the first time in Leontice species...
  50. Kostalova D, Bukovsky M, Koscova H, Kardosova A. [Anticomplement activity of Mahonia aquifolium bisbenzylisoquinoline alkaloids and berberine extract]. Ceska Slov Farm. 2001;50:286-9 pubmed
    ..aquifolium was less active than berberine or the fraction BBI alkaloids. The results indicate that the fraction of BBI alkaloids and berberine largely account for the immunomodulatory activity of the crude extract of M. aquifolium...
  51. Iwasa K, Moriyasu M, Wiegrebe W. Some contributions to the application of LC-NMR, LC-MS, and LC-CD to the biosynthesis of isoquinoline alkaloids using callus cultures. Pharmazie. 2012;67:571-85 pubmed
    ..spectroscopic techniques in combination with a special extraction and work-up of plant calli cultures of Berberidaceae, Fumariaceae, and Papaveraceae families, e.g...
  52. Kong Y, Xiao J, Meng S, Dong X, Ge Y, Wang R, et al. A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum. Fitoterapia. 2010;81:367-70 pubmed publisher
  53. Lu Y, Chen S, Wang B. Cytotoxic activities of endophytic fungi isolated from the endangered, Chinese endemic species Dysosma pleiantha. Z Naturforsch C. 2009;64:518-20 pubmed
    ..in particular, showed most potent activity with LC50 values of 4.86, 7.71, and 14.88 microg/ml, respectively. These results indicate that endophytic fungi of Dysosma pleiantha could be a promising source for antitumour agents...
  54. Diogo C, Machado N, Barbosa I, Serafim T, Burgeiro A, Oliveira P. Berberine as a promising safe anti-cancer agent - is there a role for mitochondria?. Curr Drug Targets. 2011;12:850-9 pubmed
    ..Berberine, a benzyl-tetra isoquinoline alkaloid extracted from plants of the Berberidaceae family, has been extensively used for many centuries, especially in the traditional Chinese and Native ..
  55. Huang H, Sun S, Xu J, Wang Z. [Novel application of FTIR in medical herb chemotaxonomy]. Guang Pu Xue Yu Guang Pu Fen Xi. 2003;23:253-7 pubmed
    Typical medical plants in Araliaceae, Campanulaceae, Magnoliaceae, Lauraceae, Leguminosae, Berberidaceae, Pteridophyta, etc...
  56. Gulcin I, Mshvildadze V, Gepdiremen A, Elias R. Screening of antiradical and antioxidant activity of monodesmosides and crude extract from Leontice smirnowii tuber. Phytomedicine. 2006;13:343-51 pubmed
    Leontice smirnowii is a member of the Berberidaceae family...
  57. Chen D, Zhao J, Liu X, Wang C, Zhang Z, Qin S, et al. [Genetic diversity and genetic structure of endangered wild Sinopodophyllum emodi by start codon targeted polymorphism]. Zhongguo Zhong Yao Za Zhi. 2013;38:278-83 pubmed
    ..Revealed the genetic diversity level and genetic structure characteristics in Sinopodophyllum emodi, a rare and endangered species in China...
  58. Chen J, Yu P, Yang G, Zhu H, An Z, Song D. [Identification on three kinds of Diphylleia sinensis (I)]. Zhong Yao Cai. 2008;31:354-61 pubmed
    ..In order to provide reference for the development of quality standards and distinction of authenticity, some sources of Diphylleia sinensis Li. in the market were identified by sampling...
  59. Bajpai V, Rahman A, Kang S. Chemical composition and inhibitory parameters of essential oil and extracts of Nandina domestica Thunb. to control food-borne pathogenic and spoilage bacteria. Int J Food Microbiol. 2008;125:117-22 pubmed publisher
    ..These results indicate the potential efficacy of plant-based natural products such as essential oil and organic extracts of N. domestica to control food-borne pathogenic and spoilage bacteria...
  60. Logacheva M, Penin A, Samigullin T, Vallejo Roman C, Antonov A. Phylogeny of flowering plants by the chloroplast genome sequences: in search of a "lucky gene". Biochemistry (Mosc). 2007;72:1324-30 pubmed
    ..The combination of all necessary features makes this group of genes main candidates for the role of "lucky gene" in studying phylogeny of flowering plants...
  61. Zhu Q, Liu F, Xu M, Lin X, Wang X. Ultrahigh pressure extraction of lignan compounds from Dysosma versipellis and purification by high-speed counter-current chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2012;905:145-9 pubmed publisher
    ..As a result, 73.7 mg podophyllotoxin and 16.5mg 4'-demethylpodophyllotoxin with purities over 96% were obtained from 260 mg crude sample in one-step separation...
  62. Picone J, MacTavish H, Clery R. Emission of floral volatiles from Mahonia japonica (Berberidaceae). Phytochemistry. 2002;60:611-7 pubmed
    ..7 microg/h) compared with the night-time (NT) (19.8 microgg/h) under a 6 h photoperiod and was not significantly different from total emission under a 9 h photoperiod...
  63. Zhang Y, He L, Wang H. [Inhibitory effect of taspine on mouse S180 sarcoma and its mechanism]. Zhongguo Zhong Yao Za Zhi. 2007;32:953-6 pubmed
    ..To study the inhibition effect of taspine on mouse S180 sarcoma and its mechanism...
  64. Chen J, Yu P, Yang G, Zhu H, An Z, Song D. [Identification on three kinds of Diphylleia sinensis (II)]. Zhong Yao Cai. 2008;31:501-3 pubmed
    ..In order to provide reference for the development of quality standards and distinction of authenticity, some sources of Diphylleia sinensis Li. in the maket were identified by sampling...
  65. Tang Y, Zhao W, Li H. Novel tandem biotransformation process for the biosynthesis of a novel compound, 4-(2,3,5,6-tetramethylpyrazine-1)-4'-demethylepipodophyllotoxin. Appl Environ Microbiol. 2011;77:3023-34 pubmed publisher
    ..For the first time, the novel compound 4-TMP-DMEP with superior antitumor activity was directionally synthesized from podophyllotoxin by the novel tandem biotransformation process developed in this work...
  66. Assaf A, Haddadin R, Aldouri N, Alabbassi R, Mashallah S, Mohammad M, et al. Anti-cancer, anti-inflammatory and anti-microbial activities of plant extracts used against hematological tumors in traditional medicine of Jordan. J Ethnopharmacol. 2013;145:728-36 pubmed publisher
    ..Mercurialis annua L., Bongardia chrysogonum L., and Viscum cruciatum Sieb have been traditionally used by local herbalists in Jordan for the treatment of hematopoietic neoplasms...
  67. Bajpai V, Yoon J, Kang S. Antifungal potential of essential oil and various organic extracts of Nandina domestica Thunb. against skin infectious fungal pathogens. Appl Microbiol Biotechnol. 2009;83:1127-33 pubmed publisher
    ..rubrum KCTC 6375. The present results demonstrated that N. domestica mediated oil and extracts could be potential sources of natural fungicides to control certain important dermatophytic fungi...
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    Dysosma species (Berberidaceae, Podophylloideae) are of great medicinal pharmacogenetic importance and used as model systems to study the drivers and mechanisms of species diversification of temperate plants in East Asia...
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    Leontice smirnowii is a member of the Berberidaceae family...
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    ..To obtain the full-length cDNA sequence of Secoisolariciresinol Dehydrogenase gene from Dysosma versipellis by RACE PCR,then investigate the character of Secoisolariciresinol Dehydrogenase gene...
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    ..This occurs through the repression of EGFR which mediates not only MAPK (Erk1/2) but also Akt signals...
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    ..emodi. It is suggested that the management of rational collection should be strengthen and the development of culturing and production should be meanwhile accelerated...