apium graveolens


Summary: A plant species of the family APIACEAE. The stalks are a food source.

Top Publications

  1. Bublin M, Lauer I, Oberhuber C, Alessandri S, Briza P, Radauer C, et al. Production and characterization of an allergen panel for component-resolved diagnosis of celery allergy. Mol Nutr Food Res. 2008;52 Suppl 2:S241-50 pubmed publisher
    ..These well-defined celery allergens will be used to prove the concept of component-resolved diagnosis and will contribute to improve food allergy diagnosis in the future. ..
  2. Thomas L, Forsyth V, Šturcová A, Kennedy C, May R, Altaner C, et al. Structure of cellulose microfibrils in primary cell walls from collenchyma. Plant Physiol. 2013;161:465-76 pubmed publisher
    ..Celery (Apium graveolens) collenchyma is a useful model system for the study of primary wall microfibril structure because its ..
  3. Bublin M, Radauer C, Wilson I, Kraft D, Scheiner O, Breiteneder H, et al. Cross-reactive N-glycans of Api g 5, a high molecular weight glycoprotein allergen from celery, are required for immunoglobulin E binding and activation of effector cells from allergic patients. FASEB J. 2003;17:1697-9 pubmed
    ..All these observations taken together confer convincing evidence that IgE directed to cross-reactive carbohydrates is capable of eliciting allergic reactions in vivo. ..
  4. Huang J, Chen Y, Su M, Zheng H, Yang Y, Chen J, et al. dl-3-n-Butylphthalide prevents oxidative damage and reduces mitochondrial dysfunction in an MPP(+)-induced cellular model of Parkinson's disease. Neurosci Lett. 2010;475:89-94 pubmed publisher
    ..NBP was extracted from seeds of Apium graveolens Linn. (Chinese celery)...
  5. Ballmer Weber B, Hoffmann A, Wuthrich B, Luttkopf D, Pompei C, Wangorsch A, et al. Influence of food processing on the allergenicity of celery: DBPCFC with celery spice and cooked celery in patients with celery allergy. Allergy. 2002;57:228-35 pubmed
    ..3) RBL cells sensitized with mouse IgE to raw celery may serve as a useful tool for screening the potential allergenicity of heat-processed products containing celery. ..
  6. Mencherini T, Cau A, Bianco G, Della Loggia R, Aquino R, Autore G. An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties. J Pharm Pharmacol. 2007;59:891-7 pubmed
    ..iNOS) is one of the inflammatory mediators, the effects of the ethanol/water (1:1) extract of the leaves of Apium graveolens var. dulce (celery) on iNOS expression and NO production in the J774...
  7. Bauermeister K, Ballmer Weber B, Bublin M, Fritsche P, Hanschmann K, Hoffmann Sommergruber K, et al. Assessment of component-resolved in vitro diagnosis of celeriac allergy. J Allergy Clin Immunol. 2009;124:1273-1281.e2 pubmed publisher
    ..Sensitization to Api g 5 was attributable to its glycan moieties but did not interfere with diagnostic specificity. ..
  8. Nadwodnik J, Lohaus G. Subcellular concentrations of sugar alcohols and sugars in relation to phloem translocation in Plantago major, Plantago maritima, Prunus persica, and Apium graveolens. Planta. 2008;227:1079-89 pubmed publisher
    ..of leaves of Plantago major (common plantain), Plantago maritima (sea plantain), Prunus persica (peach) and Apium graveolens (celery)...
  9. Gadermaier G, Egger M, Girbl T, Erler A, Harrer A, Vejvar E, et al. Molecular characterization of Api g 2, a novel allergenic member of the lipid-transfer protein 1 family from celery stalks. Mol Nutr Food Res. 2011;55:568-77 pubmed publisher

More Information


  1. Yao Y, Sang W, Zhou M, Ren G. Phenolic composition and antioxidant activities of 11 celery cultivars. J Food Sci. 2010;75:C9-13 pubmed publisher
    ..An extremely significant positive correlation between the antioxidant activity and the contents of total flavonoids, total phenolic acids, or total phenolics was observed in this study. ..
  2. Faeste C, Jonscher K, Sit L, Klawitter J, Løvberg K, Moen L. Differentiating cross-reacting allergens in the immunological analysis of celery (Apium graveolens) by mass spectrometry. J AOAC Int. 2010;93:451-61 pubmed
    ..Several unique precursor ion-to-product ion transitions were determined for each species, suggesting the feasibility of developing an MS-based screening method to specifically detect celery allergens in foods. ..
  3. Zhu L, Bao T, Deng Y, Li H, Chen L. Constituents from Apium graveolens and their anti-inflammatory effects. J Asian Nat Prod Res. 2017;19:1079-1086 pubmed publisher
    ..2), along with two known aglycones (3-4), were isolated from the 70% EtOH extract of fresh whole grass of Apium graveolens L. Their structures were elucidated by extensive spectroscopic analysis...
  4. Khoshkhatti N, Habibi Koohi M, Mosahebi G. Occurrence and distribution of Potato virus Y strain N (PVY(N)) on celery in Iran. Commun Agric Appl Biol Sci. 2009;74:849-52 pubmed
    Celery (Apium graveolens) is an important crop grown in many countries...
  5. Hostetler G, Riedl K, Cárdenas H, Diosa Toro M, Arango D, Schwartz S, et al. Flavone deglycosylation increases their anti-inflammatory activity and absorption. Mol Nutr Food Res. 2012;56:558-69 pubmed publisher
  6. Zhou K, Wu B, Zhuang Y, Ding L, Liu Z, Qiu F. [Chemical constituents of fresh celery]. Zhongguo Zhong Yao Za Zhi. 2009;34:1512-5 pubmed
    To study the chemical constituents of the whole plant of fresh celery (Apium graveolens)...
  7. Destaillats F, Angers P. Base-catalyzed derivatization methodology for FA analysis. application to milk fat and celery seed lipid TAG. Lipids. 2002;37:527-32 pubmed
    ..used to determine optimal reaction conditions; and bovine milk fat, containing C4 to C22 acids, and celery (Apium graveolens) seed oil, characterized by a high level of petroselinic acid, were comparatively analyzed as their ethyl, n-..
  8. Magrinyà N, Bou R, Tres A, Rius N, Codony R, Guardiola F. Effect of tocopherol extract, Staphylococcus carnosus culture, and celery concentrate addition on quality parameters of organic and conventional dry-cured sausages. J Agric Food Chem. 2009;57:8963-72 pubmed publisher
    ..As the two nitrate sources behaved similarly for the parameters studied, CP is a useful alternative to chemical ingredients for organic dry-cured sausage production. ..
  9. Sarshar S, Sendker J, Qin X, Goycoolea F, Asadi Karam M, Habibi M, et al. Antiadhesive hydroalcoholic extract from Apium graveolens fruits prevents bladder and kidney infection against uropathogenic E. coli. Fitoterapia. 2018;127:237-244 pubmed publisher
    Fruits from Apium graveolens (Celery) are used traditionally in Persian and European medicine for the treatment of uncomplicated urinary tract infections. No data are available on A...
  10. Landouar Arsivaud L, Juchaux Cachau M, Jeauffre J, Biolley J, Maurousset L, Lemoine R. The promoters of 3 celery salt-induced phloem-specific genes as new tools for monitoring salt stress responses. Plant Physiol Biochem. 2011;49:2-8 pubmed publisher
    ..a progressive 3 week salt stress (final NaCl concentration 300 mM) were identified in the phloem of celery (Apium graveolens L., cv Vert d'Elne)...
  11. Tashakori Sabzevar F, Ramezani M, Hosseinzadeh H, Parizadeh S, Movassaghi A, Ghorbani A, et al. Protective and hypoglycemic effects of celery seed on streptozotocin-induced diabetic rats: experimental and histopathological evaluation. Acta Diabetol. 2016;53:609-19 pubmed publisher
    ..The results indicated that celery seed extract can be effective in controlling hyperglycemia and hyperlipidemia in diabetic rats, and demonstrated its protective effects against pancreatic toxicity resulting from STZ-induction. ..
  12. Scoccianti V, Crinelli R, Tirillini B, Mancinelli V, Speranza A. Uptake and toxicity of Cr(III) in celery seedlings. Chemosphere. 2006;64:1695-703 pubmed
    ..The putative function of polyamines as a stress response, and the recruitment of the ubiquitin pathway to remove damaged or aberrant proteins which might have been produced in metal-treated seedlings are discussed. ..
  13. Bouchard L, Warren W. Multiple-quantum vector field imaging by magnetic resonance. J Magn Reson. 2005;177:9-21 pubmed
    ..Experiments in structured media confirm the structural sensitivity. This technique can probe length scales not accessible by conventional MRI and diffusion tensor imaging. ..
  14. Ha J, Kim S, Lee H, Kim S, Lee H. Efficacy of Combination Treatment with Sodium Metasilicate and Sodium Hypochlorite for Inactivation of Norovirus on Fresh Vegetables. Foodborne Pathog Dis. 2017;: pubmed publisher
    ..4) on lettuce (Lactuca sativa), celery (Apium graveolens L.), and white cabbage (Brassica oleracea ssp. capitata)...
  15. Horsch A, Sebranek J, Dickson J, Niebuhr S, Larson E, Lavieri N, et al. The effect of pH and nitrite concentration on the antimicrobial impact of celery juice concentrate compared with conventional sodium nitrite on Listeria monocytogenes. Meat Sci. 2014;96:400-7 pubmed publisher
    ..monocytogenes growth at 200 mg/kg nitrite than at 100 mg/kg. Celery juice concentrate may increase meat product pH which could have implications for the antimicrobial impact of nitrite in some products. ..
  16. Liu T, Liu F, Xie H, Mu Q. Phytopathogenic fungal inhibitors from celery seeds. Nat Prod Commun. 2012;7:889-90 pubmed
    Extract of celery (Apium graveolens L.) seeds was investigated against phytopathogenic fungi. The light petroleum extract showed promising inhibition activities in the tests against Rhizoctonia solani and Fusarium oxysporum f. sp...
  17. Cox G, Moreno N, Feijo J. Second-harmonic imaging of plant polysaccharides. J Biomed Opt. 2005;10:024013 pubmed
    ..This also has useful applications in imaging plant-derived starchy food products. Lignin in plant cell walls shows a strong three-photon excited fluorescence, which may be enhanced by resonance effects. ..
  18. Amirehsani K, Wallace D. Tes, Licuados, and Capsulas: herbal self-care remedies of Latino/Hispanic immigrants for type 2 diabetes. Diabetes Educ. 2013;39:828-40 pubmed publisher
    ..Diabetes educators and other health care providers need to ask Latino/Hispanic clients about their use of herbal remedies and become knowledgeable about herbal products to provide advice about safety. ..
  19. Jennings D, Daub M, Pharr D, Williamson J. Constitutive expression of a celery mannitol dehydrogenase in tobacco enhances resistance to the mannitol-secreting fungal pathogen Alternaria alternata. Plant J. 2002;32:41-9 pubmed
    ..alternata, but not to the non-mannitol-secreting fungal pathogen Cercospora nicotianae. These results are consistent with the hypothesis that MTD plays a role in resistance to mannitol-secreting fungal plant pathogens. ..
  20. Nagella P, Ahmad A, Kim S, Chung I. Chemical composition, antioxidant activity and larvicidal effects of essential oil from leaves of Apium graveolens. Immunopharmacol Immunotoxicol. 2012;34:205-9 pubmed publisher
    The leaves of Apium graveolens were extracted and the essential oil composition, immunotoxicity effects, and antioxidant activity were studied...
  21. Gao L, Feng L, Yao S, Jiao P, Qin S, Zhang W, et al. Molecular mechanisms of celery seed extract induced apoptosis via s phase cell cycle arrest in the BGC-823 human stomach cancer cell line. Asian Pac J Cancer Prev. 2011;12:2601-6 pubmed
    ..The molecular determinants of inhibition of cell proliferation as well as apoptosis of CSE may be associated with cycle arrest in the S phase. ..
  22. Jakovljevic V, Raskovic A, Popovic M, Sabo J. The effect of celery and parsley juices on pharmacodynamic activity of drugs involving cytochrome P450 in their metabolism. Eur J Drug Metab Pharmacokinet. 2002;27:153-6 pubmed
    Celery (Apium graveolens) and parsley (Petroselinum sativum), plants used worldwide in human nutrition, are the natural sources of methoxsalen...
  23. Choochote W, Tuetun B, Kanjanapothi D, Rattanachanpichai E, Chaithong U, Chaiwong P, et al. Potential of crude seed extract of celery, Apium graveolens L., against the mosquito Aedes aegypti (L.) (Diptera: Culicidae). J Vector Ecol. 2004;29:340-6 pubmed
    Crude seed extract of celery, Apium graveolens, was investigated for anti-mosquito potential, including larvicidal, adulticidal, and repellent activities against Aedes aegypti, the vector of dengue haemorrhagic fever...
  24. Xi Y, Sullivan G, Jackson A, Zhou G, Sebranek J. Effects of natural antimicrobials on inhibition of Listeria monocytogenes and on chemical, physical and sensory attributes of naturally-cured frankfurters. Meat Sci. 2012;90:130-8 pubmed publisher
    ..3 logCFU/g compared to the uncured co006Etrol (P <0.05). However, cranberry addition over 1% also resulted in significant product pH decline and negatively impacted the color, texture and sensory attributes of the frankfurters...
  25. Sultana S, Ahmed S, Jahangir T, Sharma S. Inhibitory effect of celery seeds extract on chemically induced hepatocarcinogenesis: modulation of cell proliferation, metabolism and altered hepatic foci development. Cancer Lett. 2005;221:11-20 pubmed
    The chemopreventive activity of methanolic extract of Apium graveolens seeds (celery seeds) has been investigated against Solt Farber protocol of hepatocarcinogenesis, oxidative stress and induction of positive foci of gamma-GT in the ..
  26. Zhou K, Zhao F, Liu Z, Zhuang Y, Chen L, Qiu F. Triterpenoids and flavonoids from celery (Apium graveolens). J Nat Prod. 2009;72:1563-7 pubmed publisher
    ..5), were isolated from the whole plant of fresh celery (Apium graveolens), together with 10 known flavonoids...
  27. Guerra N, Carrozzi L, Goñi M, Roura S, Yommi A. Quality characterization of celery (Apium graveolens L.) by plant zones and two harvest dates. J Food Sci. 2010;75:S327-32 pubmed publisher
    The aim of this study was to characterize the quality of celery petioles (Apium graveolens L. cv Golden Clause) from the external, middle, and internal zones of each plant...
  28. Chioti V, Zervoudakis G. Is Root Catalase a Bifunctional Catalase-Peroxidase?. Antioxidants (Basel). 2017;6: pubmed publisher
    ..leaf and root catalases from six different plant species (Lactuca sativa, Cichorium endivia, Apium graveolens, Petroselinum crispum, Lycopersicon esculentum, and Solanum melongena) correspond to the ..
  29. Jorge V, Ángel J, Adrián T, Francisco A, Anuar S, Samuel E, et al. Vasorelaxant activity of extracts obtained from Apium graveolens: possible source for vasorelaxant molecules isolation with potential antihypertensive effect. Asian Pac J Trop Biomed. 2013;3:776-9 pubmed publisher
    To investigate vasorelaxant effect of organic extracts from Apium graveolens (A...
  30. Moreno Ancillo A, Gil Adrados A, Dominguez Noche C, Cosmes P, Pineda F. Occupational asthma due to carrot in a cook. Allergol Immunopathol (Madr). 2005;33:288-90 pubmed
    ..Additional allergens may induce the sensitization. Primary sensitization due to airborne allergens of foods and the lack of pollen allergy in this patient are notorious events. ..
  31. Chatterjee A, Cui Y, Chakrabarty P, Chatterjee A. Regulation of motility in Erwinia carotovora subsp. carotovora: quorum-sensing signal controls FlhDC, the global regulator of flagellar and exoprotein genes, by modulating the production of RsmA, an RNA-binding protein. Mol Plant Microbe Interact. 2010;23:1316-23 pubmed publisher
    ..In the presence of AHL, regulatory effects of ExpR1/ExpR2 are neutralized, resulting in reduced levels of rsmA expression and enhanced motility. ..
  32. Vilke G. Food-dependent exercise-induced anaphylaxis. Prehosp Emerg Care. 2002;6:348-50 pubmed
  33. Zujovic Z, Chen D, Melton L. Comparison of celery (Apium graveolens L.) collenchyma and parenchyma cell wall polysaccharides enabled by solid-state (13)C NMR. Carbohydr Res. 2016;420:51-7 pubmed publisher
    ..4 nm, while in the parenchyma, these were somewhat larger. X-ray diffraction indicated the size of the cellulose microfibrils were the same for both types of CWs. ..
  34. Radenkovic M, Kitic D, Kostic M, Mrkaić A, Pavlovic D, Miladinovic B, et al. Effects of extracts of ginkgo, onion, and celery on the contractility of isolated rat atria. Clin Exp Hypertens. 2013;35:595-600 pubmed publisher
  35. Jiang C, Sun Y, Yu X, Gao Y, Zhang L, Wang Y, et al. Liquid-solid extraction coupled with magnetic solid-phase extraction for determination of pyrethroid residues in vegetable samples by ultra fast liquid chromatography. Talanta. 2013;114:167-75 pubmed publisher
    ..0% and 99.5%. The results showed that the present method was a simple, accurate and high efficient approach for the determination of pyrethroids in the vegetable samples. ..
  36. Lombaert G, Siemens K, Pellaers P, Mankotia M, Ng W. Furanocoumarins in celery and parsnips: method and multiyear Canadian survey. J AOAC Int. 2001;84:1135-43 pubmed
    ..Xanthotoxin had the highest mean level of positives in both celery (1.3 microg/g) and parsnips (8.5 microg/g). Little year-to-year variation in either total furanocoumarin levels or incidence was noted. ..
  37. Hostetler G, Riedl K, Schwartz S. Effects of food formulation and thermal processing on flavones in celery and chamomile. Food Chem. 2013;141:1406-11 pubmed publisher
    ..Thus, combinations of acid hydrolysis and glycosidase enzymes in almond and flax seed were most effective for developing a flavone-rich, high aglycone food ingredient from celery. ..
  38. Thimm J, Burritt D, Ducker W, Melton L. Pectins influence microfibril aggregation in celery cell walls: An atomic force microscopy study. J Struct Biol. 2009;168:337-44 pubmed publisher
  39. Han D, Row K. Determination of luteolin and apigenin in celery using ultrasonic-assisted extraction based on aqueous solution of ionic liquid coupled with HPLC quantification. J Sci Food Agric. 2011;91:2888-92 pubmed publisher
    ..7% to 89.5%. Under optimal conditions, compared with conventional solvent extraction amounts of luteolin and apigenin were more than doubled. ..
  40. Husband F, Aldick T, Van der Plancken I, Grauwet T, Hendrickx M, Skypala I, et al. High-pressure treatment reduces the immunoreactivity of the major allergens in apple and celeriac. Mol Nutr Food Res. 2011;55:1087-95 pubmed publisher
    ..The conclusion to be drawn from these results is that the combination of HP and thermal processing is an effective method to reduce the allergenicity of both apple and celeriac. ..
  41. Shivashri C, Rajarajeshwari T, Rajasekar P. Hepatoprotective action of celery (Apium graveolens) leaves in acetaminophen-fed freshwater fish (Pangasius sutchi). Fish Physiol Biochem. 2013;39:1057-69 pubmed publisher
    ..The observed hepatoprotective effect of CE might be due to its rich flavonoids. ..
  42. Xu D, Liu H, Li F, Li R. Complete genome sequence of Celery mosaic virus and its relationship to other members of the genus Potyvirus. Arch Virol. 2011;156:917-20 pubmed publisher
    ..Phylogenetic analysis based on the polyprotein sequences indicates that CeMV is most closely related to Apium virus Y, and together with Panax virus Y, the three viruses form a distinct clade. ..
  43. Hasegawa H, Chatterjee A, Cui Y, Chatterjee A. Elevated temperature enhances virulence of Erwinia carotovora subsp. carotovora strain EC153 to plants and stimulates production of the quorum sensing signal, N-acyl homoserine lactone, and extracellular proteins. Appl Environ Microbiol. 2005;71:4655-63 pubmed
    ..Our data reveal that overall metabolic activity, AHL levels, and mRNA stability are responsible for the higher levels of extracellular protein production and the enhanced virulence of EC153 at 34.5 degrees C compared to 28 degrees C...
  44. Cao J, Zhang X, Wang Q, Jia L, Zhang Y, Zhao X. Influence of flavonoid extracts from celery on oxidative stress induced by dichlorvos in rats. Hum Exp Toxicol. 2012;31:617-25 pubmed publisher
    ..The observations presented lead us to conclude the harmful effects of DIC during the exposure and the protective role of flavonoids in minimizing these effects. ..
  45. Kooti W, Moradi M, Peyro K, Sharghi M, Alamiri F, Azami M, et al. The effect of celery (Apium graveolens L.) on fertility: A systematic review. J Complement Integr Med. 2017;: pubmed publisher
    ..Keywords used in this study were "Apium graveolens L...
  46. Kolarovic J, Popovic M, Zlinská J, Trivic S, Vojnovic M. Antioxidant activities of celery and parsley juices in rats treated with doxorubicin. Molecules. 2010;15:6193-204 pubmed publisher
    ..Only parsley root juice significantly increased the content of cytochrome P450. ..
  47. Romano A, Abraham P, Rossman P, Bucaro J, Ehman R. Determination and analysis of guided wave propagation using magnetic resonance elastography. Magn Reson Med. 2005;54:893-900 pubmed
    ..Therefore, this method can permit localized tracking and characterization of wave types, velocities, and coupling along arbitrarily oriented fibers. ..
  48. Woodyer R, Christ T, Deweese K. Single-step bioconversion for the preparation of L-gulose and L-galactose. Carbohydr Res. 2010;345:363-8 pubmed publisher
    ..6 g L(-1)d(-1) and L-gulose at 0.90 g L(-1)d(-1)...
  49. Dewitt A, Andersson K, Peltre G, Lidholm J. Cloning, expression and immunological characterization of full-length timothy grass pollen allergen Phl p 4, a berberine bridge enzyme-like protein with homology to celery allergen Api g 5. Clin Exp Allergy. 2006;36:77-86 pubmed
    ..Full-length Phl p 4 cDNA was cloned and showed sequence similarity to members of the BBE family. Recombinant Phl p 4 was produced and shared epitopes with natural Phl p 4. ..
  50. Zhang Y, Huang L, Shi S, Xu S, Wang X, Peng Y. L-3-n-butylphthalide Rescues Hippocampal Synaptic Failure and Attenuates Neuropathology in Aged APP/PS1 Mouse Model of Alzheimer's Disease. CNS Neurosci Ther. 2016;22:979-987 pubmed publisher
    Our previous studies showed that L-3-n-butylphthalide (L-NBP), an extract from seeds of Apium graveolens Linn (Chinese celery), improved cognitive ability in animal models of cerebral ischemia, vascular dementia, and Alzheimer's disease (..
  51. Boonruamkaew P, Sukketsiri W, Panichayupakaranant P, Kaewnam W, Tanasawet S, Tipmanee V, et al. Apium graveolens extract influences mood and cognition in healthy mice. J Nat Med. 2017;71:492-505 pubmed publisher
    b>Apium graveolens is a food flavoring which possesses various health promoting effects. This study investigates the effect of a sub-acute administration of A...
  52. Brahmi N, Scognamiglio M, Pacifico S, Mekhoukhe A, Madani K, Fiorentino A, et al. 1H NMR based metabolic profiling of eleven Algerian aromatic plants and evaluation of their antioxidant and cytotoxic properties. Food Res Int. 2015;76:334-341 pubmed publisher
    Eleven Algerian medicinal and aromatic plants (Aloysia triphylla, Apium graveolens, Coriandrum sativum, Laurus nobilis, Lavandula officinalis, Marrubium vulgare, Mentha spicata, Inula viscosa, Petroselinum crispum, Salvia officinalis, and ..
  53. Markovic Housley Z, Basle A, Padavattan S, Maderegger B, Schirmer T, Hoffmann Sommergruber K. Structure of the major carrot allergen Dau c 1. Acta Crystallogr D Biol Crystallogr. 2009;65:1206-12 pubmed publisher
    ..This is in agreement with the observation that the majority of carrot-allergic patients have Bet v 1 cross-reactive IgE antibodies, whereas others have Dau c 1-specific IgE antibodies which do not recognize Bet v 1. ..