candida tropicalis

Summary

Summary: A species of MITOSPORIC FUNGI that is a major cause of SEPTICEMIA and disseminated CANDIDIASIS, especially in patients with LYMPHOMA; LEUKEMIA; and DIABETES MELLITUS. It is also found as part of the normal human mucocutaneous flora.

Top Publications

  1. da Silva C, de Andrade Neto J, Sidrim J, Angelo M, Magalhães H, Cavalcanti B, et al. Synergistic effects of amiodarone and fluconazole on Candida tropicalis resistant to fluconazole. Antimicrob Agents Chemother. 2013;57:1691-700 pubmed publisher
    ..In the present study, we induced resistance to fluconazole in six strains of Candida tropicalis and evaluated potential synergism between fluconazole and amiodarone...
  2. Chou H, Lo H, Chen K, Liao M, Li S. Multilocus sequence typing of Candida tropicalis shows clonal cluster enriched in isolates with resistance or trailing growth of fluconazole. Diagn Microbiol Infect Dis. 2007;58:427-33 pubmed
    Multilocus sequence typing (MLST) was used to characterize the genetic profiles of 52 Candida tropicalis isolates collected from 10 hospitals in Taiwan...
  3. Negri M, Silva S, Henriques M, Azeredo J, Svidzinski T, Oliveira R. Candida tropicalis biofilms: artificial urine, urinary catheters and flow model. Med Mycol. 2011;49:739-47 pubmed publisher
    Adhesion to medical devices and biofilm formation are considered important virulence factors of Candida tropicalis. This work aimed to use artificial urine (AU) and urinary catheters, under flow conditions, for studying C...
  4. Wang J, Li S, Yang Y, Chou H, Lo H. Association between fluconazole susceptibility and genetic relatedness among Candida tropicalis isolates in Taiwan. J Med Microbiol. 2007;56:650-3 pubmed
    Among the 162 Candida tropicalis isolates collected in the Taiwan Surveillance of Antimicrobial Resistance of Yeasts in 1999, 23 (14.2 %) had fluconazole MICs > or = 64 mg l(-1), and thus fulfilled the definition of resistance...
  5. Sendid B, Caillot D, Baccouch Humbert B, Klingspor L, Grandjean M, Bonnin A, et al. Contribution of the Platelia Candida-specific antibody and antigen tests to early diagnosis of systemic Candida tropicalis infection in neutropenic adults. J Clin Microbiol. 2003;41:4551-8 pubmed
    ..samples from seven neutropenic adult patients with hematological malignancies who had developed systemic Candida tropicalis infections...
  6. Kim J, Han K, Koh Y, Ryu Y, Seo J. Optimization of fed-batch fermentation for xylitol production by Candida tropicalis. J Ind Microbiol Biotechnol. 2002;29:16-9 pubmed
    Xylitol, a functional sweetener, was produced from xylose by biological conversion using Candida tropicalis ATCC 13803...
  7. Tavanti A, Davidson A, Johnson E, Maiden M, Shaw D, Gow N, et al. Multilocus sequence typing for differentiation of strains of Candida tropicalis. J Clin Microbiol. 2005;43:5593-600 pubmed
    A system is described for typing isolates of the pathogenic fungus Candida tropicalis, based on sequence polymorphisms in fragments of six genes: ICL1, MDR1, SAPT2, SAPT4, XYR1, and ZWF1a...
  8. Silva S, Negri M, Henriques M, Oliveira R, Williams D, Azeredo J. Candida glabrata, Candida parapsilosis and Candida tropicalis: biology, epidemiology, pathogenicity and antifungal resistance. FEMS Microbiol Rev. 2012;36:288-305 pubmed publisher
    ..albicans Candida (NCAC) species such as Candida glabrata, Candida tropicalis and Candida parapsilosis are now frequently identified as human pathogens...
  9. Lee J, Koo B, Kim S. Cloning and characterization of the xyl1 gene, encoding an NADH-preferring xylose reductase from Candida parapsilosis, and its functional expression in Candida tropicalis. Appl Environ Microbiol. 2003;69:6179-88 pubmed
    ..b>Candida tropicalis KFCC-10960 has been reported to have the highest xylitol production yield and rate...

More Information

Publications71

  1. Stiborova M, Sucha V, Miksanova M, Paca J. Hydroxylation of phenol to catechol by Candida tropicalis: involvement of cytochrome P450. Gen Physiol Biophys. 2003;22:167-79 pubmed
    Microsomal preparations isolated from yeast Candida tropicalis (C. tropicalis) grown on three different media with or without phenol were isolated and characterized for the content of cytochrome P450 (CYP) (EC 1.14.15.1)...
  2. Zhang W, Xu Z, Zhao S, Jiang J, Wang Y, Yan X. Optimization of process parameters for reduction of gossypol levels in cottonseed meal by Candida tropicalis ZD-3 during solid substrate fermentation. Toxicon. 2006;48:221-6 pubmed
    ..this work is to optimize the process parameters for detoxification of gossypol in cottonseed meal (CSM) by Candida tropicalis ZD-3 during solid substrate fermentation (SSF)...
  3. Chong P, Chieng D, Low L, Hafeez A, Shamsudin M, Seow H, et al. Recurrent candidaemia in a neonate with Hirschsprung's disease: fluconazole resistance and genetic relatedness of eight Candida tropicalis isolates. J Med Microbiol. 2006;55:423-8 pubmed
    ..We report here the repeated isolation of Candida tropicalis from the blood of a neonatal patient with Hirschsprung's disease...
  4. Rao R, Jyothi C, Prakasham R, Sarma P, Rao L. Xylitol production from corn fiber and sugarcane bagasse hydrolysates by Candida tropicalis. Bioresour Technol. 2006;97:1974-8 pubmed
    A natural isolate, Candida tropicalis was tested for xylitol production from corn fiber and sugarcane bagasse hydrolysates...
  5. Jacobsen M, Davidson A, Li S, Shaw D, Gow N, Odds F. Molecular phylogenetic analysis of Candida tropicalis isolates by multi-locus sequence typing. Fungal Genet Biol. 2008;45:1040-2 pubmed publisher
    Multi-locus sequencing data for 242 different isolates of Candida tropicalis generated a dendrogram showing 235 strains assigned to a single large recently evolved group which contained several small clonal clusters...
  6. Nucci M, Colombo A. Candidemia due to Candida tropicalis: clinical, epidemiologic, and microbiologic characteristics of 188 episodes occurring in tertiary care hospitals. Diagn Microbiol Infect Dis. 2007;58:77-82 pubmed
    b>Candida tropicalis is the 2nd most frequent agent of candidemia in Brazil (20-24%). We attempted to characterize the epidemiology, microbiology, and outcome of candidemia due to C. tropicalis by comparing patients with candidemia due to C...
  7. Porman A, Alby K, Hirakawa M, Bennett R. Discovery of a phenotypic switch regulating sexual mating in the opportunistic fungal pathogen Candida tropicalis. Proc Natl Acad Sci U S A. 2011;108:21158-63 pubmed publisher
    ..In this study we investigate Candida tropicalis, an important human fungal pathogen that has been reported to be asexual...
  8. Xie J, Du H, Guan G, Tong Y, Kourkoumpetis T, Zhang L, et al. N-acetylglucosamine induces white-to-opaque switching and mating in Candida tropicalis, providing new insights into adaptation and fungal sexual evolution. Eukaryot Cell. 2012;11:773-82 pubmed publisher
    ..In this report, we show that Candida tropicalis, another important human opportunistic pathogen, undergoes reversible and heritable phenotypic switching, ..
  9. Eirich L, Craft D, Steinberg L, Asif A, Eschenfeldt W, Stols L, et al. Cloning and characterization of three fatty alcohol oxidase genes from Candida tropicalis strain ATCC 20336. Appl Environ Microbiol. 2004;70:4872-9 pubmed
    b>Candida tropicalis (ATCC 20336) converts fatty acids to long-chain dicarboxylic acids via a pathway that includes among other reactions the oxidation of omega-hydroxy fatty acids to omega-aldehydes by a fatty alcohol oxidase (FAO)...
  10. Zeng G, Liu Z, Zhong H, Li J, Yuan X, Fu H, et al. Effect of monorhamnolipid on the degradation of n-hexadecane by Candida tropicalis and the association with cell surface properties. Appl Microbiol Biotechnol. 2011;90:1155-61 pubmed publisher
    The effect of monorhamnolipid (monoRL) on the degradation of n-hexadecane by Candida tropicalis was investigated in this study...
  11. Galán Ladero M, Blanco Blanco M, Hurtado C, Pérez Giraldo C, Blanco M, Gomez Garcia A. Determination of biofilm production by Candida tropicalis isolated from hospitalized patients and its relation to cellular surface hydrophobicity, plastic adherence and filamentation ability. Yeast. 2013;30:331-9 pubmed publisher
    b>Candida tropicalis is an emerging virulent species. The aim of this study is to determine the biofilm-forming ability of 29 strains of C...
  12. Jeon Y, Shin H, Rogers P. Xylitol production from a mutant strain of Candida tropicalis. Lett Appl Microbiol. 2011;53:106-13 pubmed publisher
    To characterize the kinetics of growth, sugar uptake and xylitol production in batch and fed-batch cultures for a xylitol assimilation-deficient strain of Candida tropicalis isolated via chemical mutagenesis.
  13. Ko B, Kim J, Kim J. Production of xylitol from D-xylose by a xylitol dehydrogenase gene-disrupted mutant of Candida tropicalis. Appl Environ Microbiol. 2006;72:4207-13 pubmed
    ..Two copies of the XYL2 gene encoding XDH in the diploid yeast Candida tropicalis were sequentially disrupted using the Ura-blasting method...
  14. Vicari P, Feitosa Pinheiro R, Chauffaille M, Yamamoto M, Figueiredo M. Septic arthritis as the first sign of Candida tropicalis fungaemia in an acute lymphoid leukemia patient. Braz J Infect Dis. 2003;7:426-8 pubmed
    ..We report the case of a 24-year-old man with acute lymphoid leukemia, who developed Candida tropicalis arthritis during an aplastic period after chemotherapy...
  15. Kothavade R, Kura M, Valand A, Panthaki M. Candida tropicalis: its prevalence, pathogenicity and increasing resistance to fluconazole. J Med Microbiol. 2010;59:873-80 pubmed publisher
    b>Candida tropicalis has been identified as the most prevalent pathogenic yeast species of the Candida-non-albicans group...
  16. Granström T, Aristidou A, Leisola M. Metabolic flux analysis of Candida tropicalis growing on xylose in an oxygen-limited chemostat. Metab Eng. 2002;4:248-56 pubmed
    We have studied the metabolism of xylose by Candida tropicalis in oxygen-limited chemostat. In vitro enzyme assays indicated that glycolytic and gluconeogenetic enzymes are expressed simultaneously facilitating substrate cycling...
  17. Ko B, Kim D, Yoon B, Bai S, Lee H, Kim J, et al. Enhancement of xylitol production by attenuation of intracellular xylitol dehydrogenase activity in Candida tropicalis. Biotechnol Lett. 2011;33:1209-13 pubmed publisher
    To construct Candida tropicalis strains that produce a high yield of xylitol with no requirement for co-substrates, we engineered the yeast with an attenuated xylitol dehydrogenase (XDH) and then assessed the efficiency of xylitol ..
  18. Mesa Arango A, Forastiero A, Bernal Martinez L, Cuenca Estrella M, Mellado E, Zaragoza O. The non-mammalian host Galleria mellonella can be used to study the virulence of the fungal pathogen Candida tropicalis and the efficacy of antifungal drugs during infection by this pathogenic yeast. Med Mycol. 2013;51:461-72 pubmed publisher
    Although Candida tropicalis is a frequent cause of invasive fungal diseases, its interaction with the host remains poorly studied...
  19. Negri M, Silva S, Henriques M, Oliveira R. Insights into Candida tropicalis nosocomial infections and virulence factors. Eur J Clin Microbiol Infect Dis. 2012;31:1399-412 pubmed publisher
    b>Candida tropicalis is considered the first or the second non-Candida albicans Candida (NCAC) species most frequently isolated from candidosis, mainly in patients admitted in intensive care units (ICUs), especially with cancer, requiring ..
  20. Steuer S, Pingoud V, Pingoud A, Wende W. Chimeras of the homing endonuclease PI-SceI and the homologous Candida tropicalis intein: a study to explore the possibility of exchanging DNA-binding modules to obtain highly specific endonucleases with altered specificity. Chembiochem. 2004;5:206-13 pubmed
    ..several chimeric proteins derived from the Saccharomyces cerevisiae VMA1 intein (PI-SceI) and the related Candida tropicalis VMA1 intein...
  21. Yang Y, Ho Y, Cheng H, Ho M, Lo H. Susceptibilities of Candida species to amphotericin B and fluconazole: the emergence of fluconazole resistance in Candida tropicalis. Infect Control Hosp Epidemiol. 2004;25:60-4 pubmed
    ..To determine the susceptibilities of Candida species isolated from Taiwan to amphotericin B and fluconazole...
  22. Craft D, Madduri K, Eshoo M, Wilson C. Identification and characterization of the CYP52 family of Candida tropicalis ATCC 20336, important for the conversion of fatty acids and alkanes to alpha,omega-dicarboxylic acids. Appl Environ Microbiol. 2003;69:5983-91 pubmed
    b>Candida tropicalis ATCC 20336 excretes alpha,omega-dicarboxylic acids as a by-product when cultured on n-alkanes or fatty acids as the carbon source...
  23. Sheu D, Duan K, Jou S, Chen Y, Chen C. Production of xylitol from Candida tropicalis by using an oxidation-reduction potential-stat controlled fermentation. Biotechnol Lett. 2003;25:2065-9 pubmed
    ..glucose-feeding for enhancing xylitol conversion from D-xylose during an oxygen-limited fermentation by Candida tropicalis. The fermentation was carried out in a 5 l jar fermenter...
  24. Wu V, Fang C, Li W, Hsueh P, Chu T. Candida tropicalis-associated bilateral renal papillary necrosis and emphysematous pyelonephritis. Clin Nephrol. 2004;62:473-5 pubmed
    ..We describe a patient with bilateral RPN and EPN caused by Candida tropicalis, who suffered from recurrent hematuria, flank pain, acute fulminant renal failure, and obstruction by a ..
  25. Zhang F, Qiao D, Xu H, Liao C, Li S, Cao Y. Cloning, expression, and characterization of xylose reductase with higher activity from Candida tropicalis. J Microbiol. 2009;47:351-7 pubmed publisher
    ..In order to study the characteristics of XR from Candida tropicalis SCTCC 300249, its XR gene (xyll) was cloned and expressed in Escherichia coli BL21 (DE3)...
  26. Rattanachomsri U, Tanapongpipat S, Eurwilaichitr L, Champreda V. Simultaneous non-thermal saccharification of cassava pulp by multi-enzyme activity and ethanol fermentation by Candida tropicalis. J Biosci Bioeng. 2009;107:488-93 pubmed publisher
    ..reaction can be performed simultaneously with the ethanol fermentation process using a thermotolerant yeast Candida tropicalis BCC7755. The combined process produced 14...
  27. Dey P, Maiti M. Molecular characterization of a novel isolate of Candida tropicalis for enhanced lipid production. J Appl Microbiol. 2013;114:1357-68 pubmed publisher
    To characterize a new isolate of Candida tropicalis for its enhanced storage lipid accumulation with respect to lipid composition, fatty acid profile and transcriptional regulation of four key genes involved in lipid productivity using ..
  28. Pasquale T, Tomada J, Ghannoun M, DiPersio J, Bonilla H. Emergence of Candida tropicalis resistant to caspofungin. J Antimicrob Chemother. 2008;61:219 pubmed
  29. Schwartz D, Morgan E. Multimodality imaging of Candida tropicalis myositis. Pediatr Radiol. 2008;38:473-6 pubmed
    ..We present a boy with biopsy proven fungal myositis who was examined with multiple imaging modalities. MR imaging proved to be very effective for diagnostic purposes, while US imaging was able to provide guidance for biopsy...
  30. Bayegan S, Majoros L, Kardos G, Kemeny Beke A, Miszti C, Kovacs R, et al. In vivo studies with a Candida tropicalis isolate exhibiting paradoxical growth in vitro in the presence of high concentration of caspofungin. J Microbiol. 2010;48:170-3 pubmed publisher
    We investigated the activity of caspofungin against a Candida tropicalis clinical isolate showing paradoxical growth in vitro. BALB/c mice immunosuppressed by cyclophosphamide were infected intraperitoneally using 10(7) CFU/mouse...
  31. He F, Chen Y. Cloning and heterologous expression of the NADPH cytochrome P450 oxidoreductase genes from an industrial dicarboxylic acid-producing Candida tropicalis. Yeast. 2005;22:481-91 pubmed
    ..of electrons during P450-mediated oxidation, which plays an important role in the omega-oxidation pathway of Candida tropicalis. Two putative allelic genes, CPR-a and CPR-b, were cloned from the long chain dicarboxylic acid-producing ..
  32. Martinez Garcia G, Johnson A, Bachmann R, Williams C, Burgoyne A, Edyvean R. Anaerobic treatment of olive mill wastewater and piggery effluents fermented with Candida tropicalis. J Hazard Mater. 2009;164:1398-405 pubmed publisher
    ..mono-cyclic phenol reduction in OMW in this study was carried out by aerobic pre-treatment using the yeast Candida tropicalis in a 18 L batch reactor at 30 degrees C for 12 days followed by anaerobic co-digestion...
  33. Okawa Y, Miyauchi M, Kobayashi H. Comparison of pathogenicity of various Candida tropicalis strains. Biol Pharm Bull. 2008;31:1507-10 pubmed
    To clarify the pathogenicity and the pathogenic factors of Candida tropicalis strains, five strains, IFO 0199, IFO 0587, IFO 0589, IFO 1400, and IFO 1647, of C...
  34. Sim J, Kho B, Liu H, Yung R, Chan J. Candida tropicalis arthritis of the knee in a patient with acute lymphoblastic leukaemia: successful treatment with caspofungin. Hong Kong Med J. 2005;11:120-3 pubmed
    Candida arthritis in patients with a haematological malignancy is rare. We report a case of Candida tropicalis arthritis of the knee that occurred in a patient with acute lymphoblastic leukaemia during the recovery phase of post-..
  35. Ruiz Ordaz N, Ruiz Lagunez J, Castañon González J, Hernández Manzano E, Cristiani Urbina E, Galindez Mayer J. Phenol biodegradation using a repeated batch culture of Candida tropicalis in a multistage bubble column. Rev Latinoam Microbiol. 2001;43:19-25 pubmed
    ..The phenol removal efficiencies obtained with this system were higher than 98.7%...
  36. Kwon S, Park S, Oh D. Increase of xylitol productivity by cell-recycle fermentation of Candida tropicalis using submerged membrane bioreactor. J Biosci Bioeng. 2006;101:13-8 pubmed
    b>Candida tropicalis, an osmophilic strain isolated from honeycomb, produced xylitol at a maximal volumetric productivity of 3.5 g l(-1) h(-1) from an initial xylose concentration of 200 g l(-1). Even at a very high xylose concentration, e...
  37. da Costa K, Ferreira J, Lavrador M, Baruffi M, Candido R. Virulence attributes and genetic variability of oral Candida albicans and Candida tropicalis isolates. Mycoses. 2012;55:e97-e105 pubmed publisher
    ..The genotypic diversity by RAPD revealed a heterogeneous population in both species. Nevertheless, C. tropicalis presented higher genetic variability than C. albicans strains...
  38. Seervai R, Jones S, Hirakawa M, Porman A, Bennett R. Parasexuality and ploidy change in Candida tropicalis. Eukaryot Cell. 2013;12:1629-40 pubmed publisher
    ..In this study, we examine ploidy changes in Candida tropicalis, a closely related species to C. albicans that was recently revealed to undergo sexual mating. C...
  39. Warn P, Sharp A, Morrissey G, Denning D. In vivo activity of micafungin in a persistently neutropenic murine model of disseminated infection caused by Candida tropicalis. J Antimicrob Chemother. 2002;50:1071-4 pubmed
    ..fluconazole in a persistently immunocompromised murine model of disseminated candidiasis against a strain of Candida tropicalis that was resistant to amphotericin B and fluconazole in vitro...
  40. Kobayashi H, Oyamada H, Matsuda K, Shibata N, Suzuki S. Distribution of antigenic oligomannosyl side chains in the cell wall mannans of several strains of Candida tropicalis. Arch Microbiol. 2003;180:76-80 pubmed
    ..the distribution of antigenic oligomannosyl side chains in the cell wall mannans of the pathogenic yeast Candida tropicalis, the chemical structure of mannans isolated from four C...
  41. Kim T, Oh D. Xylitol production by Candida tropicalis in a chemically defined medium. Biotechnol Lett. 2003;25:2085-8 pubmed
    ..was substituted for a complex medium containing yeast extract (10 g l(-1)) in the production of xylitol by Candida tropicalis. In a fed-batch culture with the chemically defined medium, 237 g xylitol l(-1) was produced from 270 g ..
  42. Dixon T, Steinbach W, Benjamin D, Williams L, Myers L. Disseminated Candida tropicalis in a patient with chronic mucocutaneous candidiasis. South Med J. 2004;97:788-90 pubmed
    ..The authors report a case of a 16-year-old with chronic mucocutaneous candidiasis who developed a fungemia with Candida tropicalis.
  43. Li S, Yang Y, Lin Y, Ko H, Wang A, Chen K, et al. Two closely related fluconazole-resistant Candida tropicalis clones circulating in Taiwan from 1999 to 2006. Microb Drug Resist. 2009;15:205-10 pubmed publisher
    Recently, we reported that diploid sequence type (DST) 140 was a predominant type of Candida tropicalis among isolates with fluconazole minimum inhibitory concentrations (MICs) >or=64 microg/ml collected in the Taiwan Surveillance of ..
  44. Porman A, Hirakawa M, Jones S, Wang N, Bennett R. MTL-independent phenotypic switching in Candida tropicalis and a dual role for Wor1 in regulating switching and filamentation. PLoS Genet. 2013;9:e1003369 pubmed publisher
    ..We discuss these findings in light of the ancestral role of Wor1 as a transcriptional regulator of the transition between yeast form and filamentous growth...
  45. Sánchez Vargas L, Ortiz López N, Villar M, Moragues M, Aguirre J, Cashat Cruz M, et al. Point prevalence, microbiology and antifungal susceptibility patterns of oral Candida isolates colonizing or infecting Mexican HIV/AIDS patients and healthy persons. Rev Iberoam Micol. 2005;22:83-92 pubmed
    ..albicans. Non-albicans species (Candida glabrata, Candida tropicalis and Candida parapsilosis, and Saccharomyces cerevisiae) were isolated from 16...
  46. Ahmad I, Shim W, Jeon W, Yoon B, Kim J. Enhancement of xylitol production in Candida tropicalis by co-expression of two genes involved in pentose phosphate pathway. Bioprocess Biosyst Eng. 2012;35:199-204 pubmed publisher
    The yeast Candida tropicalis produces xylitol, a natural, low-calorie sweetener whose metabolism does not require insulin, by catalytic activity of NADPH-dependent xylose reductase...
  47. Al Fattani M, Douglas L. Biofilm matrix of Candida albicans and Candida tropicalis: chemical composition and role in drug resistance. J Med Microbiol. 2006;55:999-1008 pubmed
    Matrix material was extracted from biofilms of Candida albicans and Candida tropicalis and analysed chemically. Both preparations contained carbohydrate, protein, hexosamine, phosphorus and uronic acid. However, the major component in C...
  48. Lima L, Pinheiro C, de Moraes L, de Freitas S, Torres F. Xylitol dehydrogenase from Candida tropicalis: molecular cloning of the gene and structural analysis of the protein. Appl Microbiol Biotechnol. 2006;73:631-9 pubmed
    ..work, we present data concerning the cloning of the XYL2 gene encoding xylitol dehydrogenase from the yeast Candida tropicalis. The gene is present as a single copy in the genome and is controlled at the transcriptional level by the ..
  49. Chai L, Denning D, Warn P. Candida tropicalis in human disease. Crit Rev Microbiol. 2010;36:282-98 pubmed publisher
    b>Candida tropicalis is one of the more common Candida causing human disease in tropical countries; the frequency of invasive disease varies by geography causing 3--66% of candidaemia. C. tropicalis is taxonomically close to C...
  50. Desnos Ollivier M, Bretagne S, Bernede C, Robert V, Raoux D, Chachaty E, et al. Clonal population of flucytosine-resistant Candida tropicalis from blood cultures, Paris, France. Emerg Infect Dis. 2008;14:557-65 pubmed publisher
    b>Candida tropicalis is a diploid ascomycetes yeast responsible for 4%-24% of candidemia. Resistance to flucytosine is rarely described for this species but was observed for 45 (35%) of 130 C...
  51. Ko B, Rhee C, Kim J. Enhancement of xylitol productivity and yield using a xylitol dehydrogenase gene-disrupted mutant of Candida tropicalis under fully aerobic conditions. Biotechnol Lett. 2006;28:1159-62 pubmed
    ..transfer rate on the xylitol production rate by a xylitol dehydrogenase gene (XYL2)-disrupted mutant of Candida tropicalis were investigated...
  52. Chai Y, Wang Y, Khoo A, Chan F, Chow C, Kumarasinghe G, et al. Predominance of Candida tropicalis bloodstream infections in a Singapore teaching hospital. Med Mycol. 2007;45:435-9 pubmed
    ..No association with ICU stay, prior exposure to fluconazole/broad-spectrum antibiotics or increased mortality was found in this apparent shift towards non-C. albicans Candida species as the primary agents of candidemia...
  53. Rehman A, Anjum M. Multiple metal tolerance and biosorption of cadmium by Candida tropicalis isolated from industrial effluents: glutathione as detoxifying agent. Environ Monit Assess. 2011;174:585-95 pubmed publisher
    The ability of cadmium uptake by metal-resistant yeast, Candida tropicalis, from the liquid medium and wastewater was evaluated. The minimum inhibitory concentration of Cd(2+) against C. tropicalis was 2,500 mg L(-1)...
  54. Torkko J, Koivuranta K, Kastaniotis A, Airenne T, Glumoff T, Ilves M, et al. Candida tropicalis expresses two mitochondrial 2-enoyl thioester reductases that are able to form both homodimers and heterodimers. J Biol Chem. 2003;278:41213-20 pubmed
    Here we report on the cloning of a Candida tropicalis gene, ETR2, that is closely related to ETR1...
  55. Negri M, Martins M, Henriques M, Svidzinski T, Azeredo J, Oliveira R. Examination of potential virulence factors of Candida tropicalis clinical isolates from hospitalized patients. Mycopathologia. 2010;169:175-82 pubmed publisher
    b>Candida tropicalis has been reported to be one of the Candida species which is most likely to cause bloodstream and urinary tract infections in hospitalized patients...
  56. Goldani L, Mário P. Candida tropicalis fungemia in a tertiary care hospital. J Infect. 2003;46:155-60 pubmed
    b>Candida tropicalis is a frequent cause of fungemia in hospitals in Latin America...
  57. Chen Y, Lo H, Wu C, Ko H, Chang T, Yang Y. Loss of heterozygosity of FCY2 leading to the development of flucytosine resistance in Candida tropicalis. Antimicrob Agents Chemother. 2011;55:2506-14 pubmed publisher
    As fluconazole resistance becomes an emerging issue for treating infections caused by Candida tropicalis, searching for alternative becomes a prominent task. In the present study, 97 clinical isolates of C...
  58. Yang S, Shao P, Hsueh P, Lin K, Huang L. Successful treatment of Candida tropicalis arthritis, osteomyelitis and costochondritis with caspofungin and fluconazole in a recipient of bone marrow transplantation. Acta Paediatr. 2006;95:629-30 pubmed
  59. Akyilmaz E, Dinckaya E. An amperometric microbial biosensor development based on Candida tropicalis yeast cells for sensitive determination of ethanol. Biosens Bioelectron. 2005;20:1263-9 pubmed
    ..For the sensitive determination of ethanol a new amperometric biosensor based on Candida tropicalis cells, which contains alcohol oxidase enzyme, immobilized in gelatin by using glutaraldehyde was developed...
  60. Shin J, Kim M, Shin D, Jung S, Kim K, Cho D, et al. Genetic relatedness among Candida tropicalis isolates from sporadic cases of fungemia in two university hospitals in Korea. Infect Control Hosp Epidemiol. 2004;25:634-40 pubmed
    To compare the epidemiology and genetic relatedness of Candida tropicalis isolates causing bloodstream infection (BSI) in two hospitals.
  61. Garcia Effron G, Kontoyiannis D, Lewis R, Perlin D. Caspofungin-resistant Candida tropicalis strains causing breakthrough fungemia in patients at high risk for hematologic malignancies. Antimicrob Agents Chemother. 2008;52:4181-3 pubmed publisher
    ..Three genetically unrelated isolates with high echinocandin MICs were identified. Each strain carried a characteristic mutation conferring an amino acid substitution within Fks1p hot spot 1...
  62. Chen K, Chen Y, Lin Y, Chou H, Li S. The molecular epidemiology of serial Candida tropicalis isolates from ICU patients as revealed by multilocus sequence typing and pulsed-field gel electrophoresis. Infect Genet Evol. 2009;9:912-20 pubmed publisher
    The genetic profiles of 50 Candida tropicalis isolates serially collected from 14 patients during a prospective surveillance study in adult intensive care units (ICUs) were characterized by multilocus sequence typing (MLST) and pulsed-..