aspergillus nidulans

Summary

Summary: A species of imperfect fungi from which the antibiotic nidulin is obtained. Its teleomorph is Emericella nidulans.

Top Publications

  1. Sieńko M, Natorff R, Owczarek S, Olewiecki I, Paszewski A. Aspergillus nidulans genes encoding reverse transsulfuration enzymes belong to homocysteine regulon. Curr Genet. 2009;55:561-70 pubmed publisher
    Homocysteine is an intermediate in methionine synthesis in Aspergillus nidulans, but it can also be converted to cysteine by the reverse transsulfuration pathway involving cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (..
  2. Bauer I, Graessle S, Loidl P, Hohenstein K, Brosch G. Novel insights into the functional role of three protein arginine methyltransferases in Aspergillus nidulans. Fungal Genet Biol. 2010;47:551-61 pubmed publisher
    ..Moreover, mycelia of DeltarmtC mutants showed a significant retardation of growth under elevated temperatures. ..
  3. Pusztahelyi T, Klement E, Szajli E, Klem J, Miskei M, Karanyi Z, et al. Comparison of transcriptional and translational changes caused by long-term menadione exposure in Aspergillus nidulans. Fungal Genet Biol. 2011;48:92-103 pubmed publisher
    ..sodium bisulfite, genome-wide transcriptional and proteome-wide translational changes were compared in Aspergillus nidulans vegetative cells...
  4. Egan M, McClintock M, Reck Peterson S. Microtubule-based transport in filamentous fungi. Curr Opin Microbiol. 2012;15:637-45 pubmed publisher
    Defects in microtubule-based transport are implicated in many neuropathologies. The filamentous fungi Aspergillus nidulans and Ustilago maydis are valuable models for studying transport owing to their yeast-like genetic and biochemical ..
  5. Tsuizaki M, Ohta A, Horiuchi H. Myosin motor-like domain of class VI chitin synthase CsmB of Aspergillus nidulans is not functionally equivalent to that of class V chitin synthase CsmA. Biosci Biotechnol Biochem. 2013;77:369-74 pubmed
    Chitin is a major cell wall component of many filamentous fungi. Among the eight chitin synthase genes of Aspergillus nidulans, csmA and csmB encode a myosin motor-like domain (MMD) and a chitin synthase domain (CSD) at their N- and C-..
  6. Kim J, Zeng C, Nayak T, Shao R, Huang A, Oakley B, et al. Timely septation requires SNAD-dependent spindle pole body localization of the septation initiation network components in the filamentous fungus Aspergillus nidulans. Mol Biol Cell. 2009;20:2874-84 pubmed publisher
    In the filamentous fungus Aspergillus nidulans, cytokinesis/septation is triggered by the septation initiation network (SIN), which first appears at the spindle pole body (SPB) during mitosis...
  7. Cao W, Maruyama J, Kitamoto K, Sumikoshi K, Terada T, Nakamura S, et al. Using a new GPI-anchored-protein identification system to mine the protein databases of Aspergillus fumigatus, Aspergillus nidulans, and Aspergillus oryzae. J Gen Appl Microbiol. 2009;55:381-93 pubmed
    ..sequences of three aspergilli, we identified 115 GPI-anchored proteins in Aspergillus fumigatus, 129 in Aspergillus nidulans, and 136 in Aspergillus oryzae...
  8. Morozov I, Jones M, Razak A, Rigden D, Caddick M. CUCU modification of mRNA promotes decapping and transcript degradation in Aspergillus nidulans. Mol Cell Biol. 2010;30:460-9 pubmed publisher
    ..Here we report that in Aspergillus nidulans both the Caf1 and Ccr4 orthologues are functionally distinct deadenylases in vivo: Caf1 is required for the ..
  9. Zhao X, Hume S, Johnson C, Thompson P, Huang J, Gray J, et al. The transcription repressor NmrA is subject to proteolysis by three Aspergillus nidulans proteases. Protein Sci. 2010;19:1405-19 pubmed publisher
    ..The transcription repressor NmrA of Aspergillus nidulans discriminates between oxidized and reduced dinucleotides, however, dinucleotide binding has no effect on ..

More Information

Publications104 found, 100 shown here

  1. Trevisan G, Oliveira E, Peres N, Cruz A, Martinez Rossi N, Rossi A. Transcription of Aspergillus nidulans pacC is modulated by alternative RNA splicing of palB. FEBS Lett. 2011;585:3442-5 pubmed publisher
    ..In addition, we show that transcription of pacC is modulated in response to alternative RNA splicing of the palB gene. These results reveal novel aspects of the complex network involved in modulation of pacC. ..
  2. Calcagno Pizarelli A, Hervás Aguilar A, Galindo A, Abenza J, Peñalva M, Arst H. Rescue of Aspergillus nidulans severely debilitating null mutations in ESCRT-0, I, II and III genes by inactivation of a salt-tolerance pathway allows examination of ESCRT gene roles in pH signalling. J Cell Sci. 2011;124:4064-76 pubmed publisher
    ..Our data support a model in which certain ESCRT proteins are recruited to the plasma membrane to mediate pH signalling. ..
  3. Shin K, Kwon N, Kim Y, Park H, Kwon G, Yu J. Differential roles of the ChiB chitinase in autolysis and cell death of Aspergillus nidulans. Eukaryot Cell. 2009;8:738-46 pubmed publisher
    ..cells becomes a predominant phenomenon in the absence of the regulator of G protein signaling FlbA in Aspergillus nidulans. Among a number of potential hydrolytic enzymes in the A...
  4. Roumelioti K, Vangelatos I, Sophianopoulou V. A cryptic role of a glycolytic-gluconeogenic enzyme (aldolase) in amino acid transporter turnover in Aspergillus nidulans. Fungal Genet Biol. 2010;47:254-67 pubmed publisher
    In Aspergillus nidulans the fbaA1013 mutation results in reduced or total loss of growth on glycolytic and gluconeogenic carbon sources, respectively...
  5. Nahlik K, Dumkow M, Bayram Ö, Helmstaedt K, Busch S, Valerius O, et al. The COP9 signalosome mediates transcriptional and metabolic response to hormones, oxidative stress protection and cell wall rearrangement during fungal development. Mol Microbiol. 2010;78:964-79 pubmed publisher
    ..in CSN result in embryonic impairment and death in higher eukaryotes, whereas the filamentous fungus Aspergillus nidulans survives without CSN, but is unable to complete sexual development...
  6. Dos Reis T, Menino J, Bom V, Brown N, Colabardini A, Savoldi M, et al. Identification of glucose transporters in Aspergillus nidulans. PLoS ONE. 2013;8:e81412 pubmed publisher
    To characterize the mechanisms involved in glucose transport, in the filamentous fungus Aspergillus nidulans, we have identified four glucose transporter encoding genes hxtB-E...
  7. Etxebeste O, Herrero Garcia E, Araújo Bazán L, Rodríguez Urra A, Garzia A, Ugalde U, et al. The bZIP-type transcription factor FlbB regulates distinct morphogenetic stages of colony formation in Aspergillus nidulans. Mol Microbiol. 2009;73:775-89 pubmed publisher
    Conidiophore formation in Aspergillus nidulans involves a developmental programme in which vegetative hyphae give rise to an ordered succession of differentiated cells: foot cell, stalk, vesicle, metulae, phialides and conidia...
  8. Ruger Herreros C, Rodriguez Romero J, Fernández Barranco R, Olmedo M, Fischer R, Corrochano L, et al. Regulation of conidiation by light in Aspergillus nidulans. Genetics. 2011;188:809-22 pubmed publisher
    ..To understand how light regulates fungal development at the molecular level we have used Aspergillus nidulans as a model...
  9. Yin W, Amaike S, Wohlbach D, Gasch A, Chiang Y, Wang C, et al. An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR. Mol Microbiol. 2012;83:1024-34 pubmed publisher
    ..RsmA greatly increases SM production by binding to two sites in the Aspergillus nidulans AflR promoter region, a C6 transcription factor known for activating production of the carcinogenic and ..
  10. Schoustra S, Rundle H, Dali R, Kassen R. Fitness-associated sexual reproduction in a filamentous fungus. Curr Biol. 2010;20:1350-5 pubmed publisher
    ..We provide evidence using 53 genotypes of the filamentous fungus Aspergillus nidulans in a reciprocal transplant experiment across three environments...
  11. Chung D, Greenwald C, Upadhyay S, Ding S, Wilkinson H, Ebbole D, et al. acon-3, the Neurospora crassa ortholog of the developmental modifier, medA, complements the conidiation defect of the Aspergillus nidulans mutant. Fungal Genet Biol. 2011;48:370-6 pubmed publisher
    b>Aspergillus nidulans and Neurospora crassa are ascomycetes that produce asexual spores through morphologically distinct processes. MedA, a protein with unknown function, is required for normal asexual and sexual development in A. nidulans...
  12. De Groot P, Brandt B, Horiuchi H, Ram A, de Koster C, Klis F. Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans. Fungal Genet Biol. 2009;46 Suppl 1:S72-81 pubmed
    ..is of high relevance to medicine and food safety, and for biotechnological applications. The cell wall of Aspergillus nidulans is composed of galactomannoproteins, 1,3-alpha-glucan, beta-glucans, and chitin...
  13. Park H, Yu J. Multi-copy genetic screen in Aspergillus nidulans. Methods Mol Biol. 2012;944:183-90 pubmed publisher
    ..Here, we describe a working protocol for the identification of novel regulators in Aspergillus nidulans.
  14. Affeldt K, Brodhagen M, Keller N. Aspergillus oxylipin signaling and quorum sensing pathways depend on g protein-coupled receptors. Toxins (Basel). 2012;4:695-717 pubmed publisher
    ..The finding of GPCRs that regulate production of survival structures (sclerotia), inoculum (spores) and aflatoxin holds promise for future development of anti-fungal therapeutics. ..
  15. Kim H, Chae K, Han K, Han D. The nsdC gene encoding a putative C2H2-type transcription factor is a key activator of sexual development in Aspergillus nidulans. Genetics. 2009;182:771-83 pubmed publisher
    The formation of the Aspergillus nidulans fruiting body is affected by a number of genetic and environmental factors...
  16. Xiong Y, Oakley B. In vivo analysis of the functions of gamma-tubulin-complex proteins. J Cell Sci. 2009;122:4218-27 pubmed publisher
    ..the function(s) of gamma-tubulin-complex proteins (GCPs), we identified and analyzed the functions of the Aspergillus nidulans homologs of GCP2-GCP6 (here designated GCPB-GCBF)...
  17. Morozov I, Jones M, Spiller D, Rigden D, Dattenböck C, Novotny R, et al. Distinct roles for Caf1, Ccr4, Edc3 and CutA in the co-ordination of transcript deadenylation, decapping and P-body formation in Aspergillus nidulans. Mol Microbiol. 2010;76:503-16 pubmed publisher
    ..We have undertaken confocal fluorescence microscopy to monitor P-bodies in Aspergillus nidulans. As in other organisms a dynamic shift in P-body formation occurs in response to diverse physiological ..
  18. Gao L, Song Y, Cao J, Wang S, Wei H, Jiang H, et al. Osmotic stabilizer-coupled suppression of NDR defects is dependent on the calcium-calcineurin signaling cascade in Aspergillus nidulans. Cell Signal. 2011;23:1750-7 pubmed publisher
    ..a member of the NDR protein kinase family, forms a complex with MobB to regulate cell polarized growth in Aspergillus nidulans. Our previous study demonstrated that mobB/cotA defects could be suppressed by the osmotic stress in the ..
  19. Chen S, Song Y, Cao J, Wang G, Wei H, Xu X, et al. Localization and function of calmodulin in live-cells of Aspergillus nidulans. Fungal Genet Biol. 2010;47:268-78 pubmed publisher
    ..Here, we described the dynamic localization of Aspergillus nidulans CaM (AnCaM) in live-cells by using recombination strains with homologous, single cross-over insertions at ..
  20. An C, Li X, Li C, Wang M, Xu G, Wang B. Aniquinazolines A-D, four new quinazolinone alkaloids from marine-derived endophytic fungus Aspergillus nidulans. Mar Drugs. 2013;11:2682-94 pubmed publisher
    ..alkaloids, namely, aniquinazolines A-D (1-4), were isolated and identified from the culture of Aspergillus nidulans MA-143, an endophytic fungus obtained from the leaves of marine mangrove plant Rhizophora stylosa...
  21. Wang J, Hu H, Wang S, Shi J, Chen S, Wei H, et al. The important role of actinin-like protein (AcnA) in cytokinesis and apical dominance of hyphal cells in Aspergillus nidulans. Microbiology. 2009;155:2714-25 pubmed publisher
    ..the identification and characterization of an actinin-like protein (AcnA) from the filamentous fungus Aspergillus nidulans. Not only did the depletion of AcnA by alcA(p) promoter repression or the deletion of AcnA result in ..
  22. Masuo S, Terabayashi Y, Shimizu M, Fujii T, Kitazume T, Takaya N. Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia. Mol Genet Genomics. 2010;284:415-24 pubmed publisher
    ..Here, we used whole genome DNA microarrays to investigate global transcriptional changes in Aspergillus nidulans gene expression after exposure to hypoxia followed by normoxia...
  23. Christensen U, Gruben B, Madrid S, Mulder H, Nikolaev I, de Vries R. Unique regulatory mechanism for D-galactose utilization in Aspergillus nidulans. Appl Environ Microbiol. 2011;77:7084-7 pubmed publisher
    This study describes two novel regulators, GalX and GalR, that control d-galactose utilization in Aspergillus nidulans. This system is unique for A. nidulans since no GalR homologs were found in other ascomycetes...
  24. Kwon N, Park H, Jung S, Kim S, Yu J. The putative guanine nucleotide exchange factor RicA mediates upstream signaling for growth and development in Aspergillus. Eukaryot Cell. 2012;11:1399-412 pubmed publisher
    ..we characterized ricA, which encodes a putative GDP/GTP exchange factor for G proteins in the model fungus Aspergillus nidulans and the opportunistic human pathogen Aspergillus fumigatus...
  25. Chen P, Gao R, Chen S, Pu L, Li P, Huang Y, et al. A pericentrin-related protein homolog in Aspergillus nidulans plays important roles in nucleus positioning and cell polarity by affecting microtubule organization. Eukaryot Cell. 2012;11:1520-30 pubmed publisher
    ..we characterized AnPcpA, a putative homolog of pericentrin-related protein in the model filamentous fungus Aspergillus nidulans, and found that it is essential for conidial germination and hyphal development...
  26. De Souza C, Hashmi S, Osmani A, Andrews P, Ringelberg C, Dunlap J, et al. Functional analysis of the Aspergillus nidulans kinome. PLoS ONE. 2013;8:e58008 pubmed publisher
    ..The filamentous fungus Aspergillus nidulans has long been utilized as a powerful molecular genetic system and recent technical advances have made ..
  27. Hervás Aguilar A, Rodríguez Galán O, Galindo A, Abenza J, Arst H, Peñalva M. Characterization of Aspergillus nidulans DidB Did2, a non-essential component of the multivesicular body pathway. Fungal Genet Biol. 2010;47:636-46 pubmed publisher
    ..We studied the localization of largely uncharacterized Aspergillus nidulans ESCRT-III using its key structural component Vps32 and the 'associated' component DidB(Did2)...
  28. Soukup A, Chiang Y, Bok J, Reyes Dominguez Y, Oakley B, Wang C, et al. Overexpression of the Aspergillus nidulans histone 4 acetyltransferase EsaA increases activation of secondary metabolite production. Mol Microbiol. 2012;86:314-30 pubmed publisher
    Regulation of secondary metabolite (SM) gene clusters in Aspergillus nidulans has been shown to occur through cluster-specific transcription factors or through global regulators of chromatin structure such as histone methyltransferases, ..
  29. Szilágyi M, Miskei M, Karanyi Z, Lenkey B, Pocsi I, Emri T. Transcriptome changes initiated by carbon starvation in Aspergillus nidulans. Microbiology. 2013;159:176-90 pubmed publisher
    ..Due to the increased production of extracellular and vacuolar enzymes during carbon starvation, the importance of the endoplasmic reticulum increased considerably. ..
  30. Ryan K, Moore C, Panaccione D. Partial reconstruction of the ergot alkaloid pathway by heterologous gene expression in Aspergillus nidulans. Toxins (Basel). 2013;5:445-55 pubmed publisher
    ..from the human-pathogenic, ergot alkaloid-producing fungus Aspergillus fumigatus and transformed into Aspergillus nidulans, a model fungus that does not contain any of the ergot alkaloid synthesis genes...
  31. Robellet X, Oestreicher N, Guitton A, Vélot C. Gene silencing of transgenes inserted in the Aspergillus nidulans alcM and/or alcS loci. Curr Genet. 2010;56:341-8 pubmed publisher
    ..systematic disruption of the genes of unknown function in the alc gene cluster from the filamentous fungus Aspergillus nidulans, we observed a strong diminution of the transcription of markers inserted in the alcS gene...
  32. Szewczyk E, Oakley B. Microtubule dynamics in mitosis in Aspergillus nidulans. Fungal Genet Biol. 2011;48:998-9 pubmed publisher
    Mitosis in Aspergillus nidulans is very rapid, requiring less than 5 min at 37 °C in germlings (Bergen and Morris, 1983)...
  33. Braus G, Irniger S, Bayram Ö. Fungal development and the COP9 signalosome. Curr Opin Microbiol. 2010;13:672-6 pubmed publisher
    ..This includes the circadian rhythm of Neurospora crassa or the repression of sexual development by light in Aspergillus nidulans. In contrast to plants and animals, CSN is not essential for fungal viability...
  34. Araújo Bazán L, Dhingra S, Chu J, Fernandez Martinez J, Calvo A, Espeso E. Importin alpha is an essential nuclear import carrier adaptor required for proper sexual and asexual development and secondary metabolism in Aspergillus nidulans. Fungal Genet Biol. 2009;46:506-15 pubmed publisher
    ..KapA, the Aspergillus nidulans importin alpha, is an essential protein...
  35. Afroz S, El Ganiny A, Sanders D, Kaminskyj S. Roles of the Aspergillus nidulans UDP-galactofuranose transporter, UgtA in hyphal morphogenesis, cell wall architecture, conidiation, and drug sensitivity. Fungal Genet Biol. 2011;48:896-903 pubmed publisher
  36. Maiya S, Grundmann A, Li S, Turner G. Improved tryprostatin B production by heterologous gene expression in Aspergillus nidulans. Fungal Genet Biol. 2009;46:436-40 pubmed
    ..culture by expression of genes of the fumitremorgin cluster from Aspergillus fumigatus in the naïve host Aspergillus nidulans using the alcA promoter...
  37. Higashitsuji Y, Herrero S, Takeshita N, Fischer R. The cell end marker protein TeaC is involved in growth directionality and septation in Aspergillus nidulans. Eukaryot Cell. 2009;8:957-67 pubmed publisher
    ..The latest results suggest that this machinery is conserved from fission yeast to Aspergillus nidulans. Here, we have characterized TeaC, a putative homologue of Tea4...
  38. Goto M, Harada Y, Oka T, Matsumoto S, Takegawa K, Furukawa K. Protein O-mannosyltransferases B and C support hyphal development and differentiation in Aspergillus nidulans. Eukaryot Cell. 2009;8:1465-74 pubmed publisher
    b>Aspergillus nidulans possesses three pmt genes encoding protein O-d-mannosyltransferases (Pmt)...
  39. Etxebeste O, Markina Iñarrairaegui A, Garzia A, Herrero Garcia E, Ugalde U, Espeso E. KapI, a non-essential member of the Pse1p/Imp5 karyopherin family, controls colonial and asexual development in Aspergillus nidulans. Microbiology. 2009;155:3934-45 pubmed publisher
    Asexual development in the filamentous fungus Aspergillus nidulans is governed by the timely expression and cellular localization of multiple transcription factors...
  40. Han K, Chun Y, Figueiredo B, Soriani F, Savoldi M, Almeida A, et al. The conserved and divergent roles of carbonic anhydrases in the filamentous fungi Aspergillus fumigatus and Aspergillus nidulans. Mol Microbiol. 2010;75:1372-88 pubmed publisher
    ..Defects in the CAs can affect Aspergilli conidiation. Furthermore, A. fumigatus DeltacafA, DeltacafB, DeltacafC, DeltacafD and DeltacafA DeltacafB mutant strains are fully virulent in a low-dose murine infection...
  41. Patananan A, Palmer J, Garvey G, Keller N, Clarke S. A novel automethylation reaction in the Aspergillus nidulans LaeA protein generates S-methylmethionine. J Biol Chem. 2013;288:14032-45 pubmed publisher
    ..In this work we did not find a methyl-accepting substrate in Aspergillus nidulans with various assays, including in vivo S-adenosyl-[methyl-(3)H]methionine labeling, targeted in vitro ..
  42. Abenza J, Galindo A, Pantazopoulou A, Gil C, de los Ríos V, Peñalva M. Aspergillus RabB Rab5 integrates acquisition of degradative identity with the long distance movement of early endosomes. Mol Biol Cell. 2010;21:2756-69 pubmed publisher
    b>Aspergillus nidulans early endosomes display characteristic long-distance bidirectional motility...
  43. Wang C, Shim W, Shaw B. Aspergillus nidulans striatin (StrA) mediates sexual development and localizes to the endoplasmic reticulum. Fungal Genet Biol. 2010;47:789-99 pubmed publisher
    ..In this study, we characterized the functions and localization of the striatin ortholog, StrA, in Aspergillus nidulans. deltastrA strains showed multiple defects in conidium germination, mycelial radial growth, production of ..
  44. Morozov I, Jones M, Gould P, Crome V, Wilson J, Hall A, et al. mRNA 3' tagging is induced by nonsense-mediated decay and promotes ribosome dissociation. Mol Cell Biol. 2012;32:2585-95 pubmed publisher
    ..We now report that Arabidopsis thaliana mRNA is subject to 3' tagging with U and C nucleotides, as in Aspergillus nidulans. Mutations that disrupt tagging, including A...
  45. Markina Iñarrairaegui A, Pantazopoulou A, Espeso E, Peñalva M. The Aspergillus nidulans peripheral ER: disorganization by ER stress and persistence during mitosis. PLoS ONE. 2013;8:e67154 pubmed publisher
    The genetically amenable fungus Aspergillus nidulans is well suited for cell biology studies involving the secretory pathway and its relationship with hyphal tip growth by apical extension...
  46. Hagiwara D, Asano Y, Marui J, Yoshimi A, Mizuno T, Abe K. Transcriptional profiling for Aspergillusnidulans HogA MAPK signaling pathway in response to fludioxonil and osmotic stress. Fungal Genet Biol. 2009;46:868-78 pubmed publisher
    ..The complexity of the stress response in the His-Asp phosphorelay system followed by the HogA MAPK cascade is discussed...
  47. Kriangkripipat T, Momany M. Aspergillus nidulans protein O-mannosyltransferases play roles in cell wall integrity and developmental patterning. Eukaryot Cell. 2009;8:1475-85 pubmed publisher
    ..Fungal Pmts are divided into three subfamilies, Pmt1, -2, and -4. Aspergillus nidulans possesses a single representative of each Pmt subfamily, pmtA (subfamily 2), pmtB (subfamily 1), and pmtC (..
  48. Rodríguez Urra A, Jimenez C, Dueñas M, Ugalde U. Bicarbonate gradients modulate growth and colony morphology in Aspergillus nidulans. FEMS Microbiol Lett. 2009;300:216-21 pubmed publisher
    ..A survey of chemical signals controlling changes in hyphal growth and branching of Aspergillus nidulans in solid minimal medium revealed that progressive accumulation of bicarbonate from the periphery to the ..
  49. Battaglia E, Hansen S, Leendertse A, Madrid S, Mulder H, Nikolaev I, et al. Regulation of pentose utilisation by AraR, but not XlnR, differs in Aspergillus nidulans and Aspergillus niger. Appl Microbiol Biotechnol. 2011;91:387-97 pubmed publisher
    ..involves the transcriptional activators AraR and XlnR, which are also present in other Aspergilli such as Aspergillus nidulans. The comparative analysis revealed that the regulation of the PCP by AraR differs in A. nidulans and A...
  50. Liu T, Chiang Y, Somoza A, Oakley B, Wang C. Engineering of an "unnatural" natural product by swapping polyketide synthase domains in Aspergillus nidulans. J Am Chem Soc. 2011;133:13314-6 pubmed publisher
    ..Structure elucidation allowed us to propose a likely pathway, and feeding studies supported the hypothesis that the chain length of PKS metabolites may be under precise control of KS and PT domains...
  51. Nützmann H, Reyes Dominguez Y, Scherlach K, Schroeckh V, Horn F, Gacek A, et al. Bacteria-induced natural product formation in the fungus Aspergillus nidulans requires Saga/Ada-mediated histone acetylation. Proc Natl Acad Sci U S A. 2011;108:14282-7 pubmed publisher
    ..Recently, we discovered that intimate physical interaction of the important model fungus Aspergillus nidulans with the soil-dwelling bacterium Streptomyces rapamycinicus specifically activated silent fungal secondary ..
  52. Yao X, Zhang J, Zhou H, Wang E, Xiang X. In vivo roles of the basic domain of dynactin p150 in microtubule plus-end tracking and dynein function. Traffic. 2012;13:375-87 pubmed publisher
    ..Nat Rev Mol Cell Biol 2008;9:309-322.). Here, we tested in the filamentous fungus Aspergillus nidulans the requirement for plus-end localization of dynactin p150, a protein essential for dynein function...
  53. Wartenberg D, Vödisch M, Kniemeyer O, Albrecht Eckardt D, Scherlach K, Winkler R, et al. Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin. J Proteomics. 2012;75:4038-49 pubmed publisher
    ..the antifungal activity of farnesol, we performed 2D-differential gel electrophoretic analysis (2D-DIGE) of Aspergillus nidulans exposed to farnesol...
  54. Bok J, Chiang Y, Szewczyk E, Reyes Dominguez Y, Davidson A, Sanchez J, et al. Chromatin-level regulation of biosynthetic gene clusters. Nat Chem Biol. 2009;5:462-4 pubmed publisher
    Loss-of-function Aspergillus nidulans CclA, a Bre2 ortholog involved in histone H3 lysine 4 methylation, activated the expression of cryptic secondary metabolite clusters in A. nidulans...
  55. Shimizu M, Fujii T, Masuo S, Takaya N. Mechanism of de novo branched-chain amino acid synthesis as an alternative electron sink in hypoxic Aspergillus nidulans cells. Appl Environ Microbiol. 2010;76:1507-15 pubmed publisher
    Although branched-chain amino acids are synthesized as building blocks of proteins, we found that the fungus Aspergillus nidulans excretes them into the culture medium under hypoxia...
  56. Kosti V, Papageorgiou I, Diallinas G. Dynamic elements at both cytoplasmically and extracellularly facing sides of the UapA transporter selectively control the accessibility of substrates to their translocation pathway. J Mol Biol. 2010;397:1132-43 pubmed publisher
    In the UapA uric acid-xanthine permease of Aspergillus nidulans, subtle interactions between key residues of the putative substrate binding pocket, located in the TMS8-TMS9 loop (where TMS is transmembrane segment), and a specificity ..
  57. Hynes M, Murray S. ATP-citrate lyase is required for production of cytosolic acetyl coenzyme A and development in Aspergillus nidulans. Eukaryot Cell. 2010;9:1039-48 pubmed publisher
    ..In the filamentous ascomycete Aspergillus nidulans, tandem divergently transcribed genes (aclA and aclB) encode the subunits of ATP-citrate lyase, and we have ..
  58. Amillis S, Kosti V, Pantazopoulou A, Mikros E, Diallinas G. Mutational analysis and modeling reveal functionally critical residues in transmembrane segments 1 and 3 of the UapA transporter. J Mol Biol. 2011;411:567-80 pubmed publisher
    ..identified mutations in the first transmembrane segment (TMS1) of UapA, a uric acid-xanthine transporter in Aspergillus nidulans, that affect its turnover and subcellular localization...
  59. Szilágyi M, Kwon N, Bakti F, M Hamvas M, Jámbrik K, Park H, et al. Extracellular proteinase formation in carbon starving Aspergillus nidulans cultures--physiological function and regulation. J Basic Microbiol. 2011;51:625-34 pubmed publisher
    Extracellular proteinase formation in carbon depleted cultures of the model filamentous fungus Aspergillus nidulans was studied to elucidate its regulation and possible physiological function...
  60. Schoustra S, Punzalan D. Correlation of mycelial growth rate with other phenotypic characters in evolved genotypes of Aspergillus nidulans. Fungal Biol. 2012;116:630-6 pubmed publisher
    ..measured as an increased mycelial growth rate, has correlated responses in the filamentous fungus Aspergillus nidulans with several other metric characters that could be important fitness components (colony forming units, ..
  61. Park H, Yu J. Genetic control of asexual sporulation in filamentous fungi. Curr Opin Microbiol. 2012;15:669-77 pubmed publisher
    ..Light is one of the key environmental factors affecting conidiation. Developmental mechanisms in Aspergillus nidulans and Neurospora crassa have been intensively studied, leading to important outlines...
  62. Yamakawa Y, Endo Y, Li N, Yoshizawa M, Aoyama M, Watanabe A, et al. Regulation of cellulolytic genes by McmA, the SRF-MADS box protein in Aspergillus nidulans. Biochem Biophys Res Commun. 2013;431:777-82 pubmed publisher
    Cellobiose triggers the production of two endoglucanases, EglA and EglB, in Aspergillus nidulans. The cellulose responsive element (CeRE) cis-element that is essential for induction has been identified on the eglA promoter, but ..
  63. Garzia A, Etxebeste O, Herrero Garcia E, Ugalde U, Espeso E. The concerted action of bZip and cMyb transcription factors FlbB and FlbD induces brlA expression and asexual development in Aspergillus nidulans. Mol Microbiol. 2010;75:1314-24 pubmed publisher
    ..This sequence of regulatory events resembles developmental control mechanisms involving c-Myb and bZip counterparts in metazoans and plants...
  64. Helmstaedt K, Schwier E, Christmann M, Nahlik K, Westermann M, Harting R, et al. Recruitment of the inhibitor Cand1 to the cullin substrate adaptor site mediates interaction to the neddylation site. Mol Biol Cell. 2011;22:153-64 pubmed publisher
    ..The separation of a single cand1 into two independent genes represents the in vivo situation of the fungus Aspergillus nidulans, where C-terminal Cand1 recruits smaller N-terminal Cand1 in the cytoplasm...
  65. Pantazopoulou A, Peñalva M. Characterization of Aspergillus nidulans RabC/Rab6. Traffic. 2011;12:386-406 pubmed publisher
    The Aspergillus nidulans Golgi is not stacked. Early and late Golgi equivalents (GEs) are intermingled but can be resolved by epifluorescence microscopy...
  66. Baidya S, Cary J, Grayburn W, Calvo A. Role of nitric oxide and flavohemoglobin homolog genes in Aspergillus nidulans sexual development and mycotoxin production. Appl Environ Microbiol. 2011;77:5524-8 pubmed publisher
    ..These proteins are involved in reducing nitric oxide levels. Deletion of the Aspergillus nidulans flavohemoglobin gene fhbA induced sexual development and decreased sterigmatocystin production...
  67. Papini M, Nookaew I, Siewers V, Nielsen J. Physiological characterization of recombinant Saccharomyces cerevisiae expressing the Aspergillus nidulans phosphoketolase pathway: validation of activity through 13C-based metabolic flux analysis. Appl Microbiol Biotechnol. 2012;95:1001-10 pubmed publisher
    ..In Aspergillus nidulans, the utilization of this metabolic pathway leads to increased carbon flow towards acetate and acetyl CoA...
  68. Andersen M, Nielsen J, Klitgaard A, Petersen L, Zachariasen M, Hansen T, et al. Accurate prediction of secondary metabolite gene clusters in filamentous fungi. Proc Natl Acad Sci U S A. 2013;110:E99-107 pubmed publisher
    ..In this study, we design and apply a DNA expression array for Aspergillus nidulans in combination with legacy data to form a comprehensive gene expression compendium...
  69. Ramamoorthy V, Dhingra S, Kincaid A, Shantappa S, Feng X, Calvo A. The putative C2H2 transcription factor MtfA is a novel regulator of secondary metabolism and morphogenesis in Aspergillus nidulans. PLoS ONE. 2013;8:e74122 pubmed publisher
    Secondary metabolism in the model fungus Aspergillus nidulans is controlled by the conserved global regulator VeA, which also governs morphological differentiation...
  70. An C, Li X, Luo H, Li C, Wang M, Xu G, et al. 4-Phenyl-3,4-dihydroquinolone derivatives from Aspergillus nidulans MA-143, an endophytic fungus isolated from the mangrove plant Rhizophora stylosa. J Nat Prod. 2013;76:1896-901 pubmed publisher
    ..1-6) along with the related aflaquinolone A (7) were isolated and identified from the cultures of Aspergillus nidulans MA-143, an endophytic fungus obtained from the fresh leaves of the marine mangrove plant Rhizophora stylosa...
  71. Coutinho P, Andersen M, Kolenova K, vanKuyk P, Benoit I, Gruben B, et al. Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae. Fungal Genet Biol. 2009;46 Suppl 1:S161-S169 pubmed
    The plant polysaccharide degradative potential of Aspergillus nidulans was analysed in detail and compared to that of Aspergillus niger and Aspergillus oryzae using a combination of bioinformatics, physiology and transcriptomics...
  72. Arnaud M, Chibucos M, Costanzo M, Crabtree J, Inglis D, Lotia A, et al. The Aspergillus Genome Database, a curated comparative genomics resource for gene, protein and sequence information for the Aspergillus research community. Nucleic Acids Res. 2010;38:D420-7 pubmed publisher
    ..All of these data are freely available at http://www.aspgd.org. We welcome feedback from users and the research community at aspergillus-curator@genome.stanford.edu...
  73. Binder U, Oberparleiter C, Meyer V, Marx F. The antifungal protein PAF interferes with PKC/MPK and cAMP/PKA signalling of Aspergillus nidulans. Mol Microbiol. 2010;75:294-307 pubmed publisher
    The Penicillium chrysogenum antifungal protein PAF inhibits polar growth and induces apoptosis in Aspergillus nidulans. We report here that two signalling cascades are implicated in its antifungal activity...
  74. Rodríguez Urra A, Jimenez C, Nieto M, Rodriguez J, Hayashi H, Ugalde U. Signaling the induction of sporulation involves the interaction of two secondary metabolites in Aspergillus nidulans. ACS Chem Biol. 2012;7:599-606 pubmed publisher
    When growing Aspergillus nidulans hyphae encounter the atmosphere, they initiate a morphogenetic program leading to the production of spores...
  75. Fekete E, Karaffa L, Seiboth B, Fekete E, Kubicek C, Flipphi M. Identification of a permease gene involved in lactose utilisation in Aspergillus nidulans. Fungal Genet Biol. 2012;49:415-25 pubmed publisher
    Lactose is intracellularly hydrolysed by Aspergillus nidulans. Classical mutation mapping data and the physical characteristics of the previously purified glycosyl hydrolase facilitated identification of the clustered, divergently ..
  76. Leung J, Cameron A, Diallinas G, Byrne B. Stabilizing the heterologously expressed uric acid-xanthine transporter UapA from the lower eukaryote Aspergillus nidulans. Mol Membr Biol. 2013;30:32-42 pubmed publisher
    ..Long-term stability analysis revealed that G411V?1-11 was the most stable construct and the most suited to downstream structural studies...
  77. Yoshimi A, Sano M, Inaba A, Kokubun Y, Fujioka T, Mizutani O, et al. Functional analysis of the ?-1,3-glucan synthase genes agsA and agsB in Aspergillus nidulans: agsB is the major ?-1,3-glucan synthase in this fungus. PLoS ONE. 2013;8:e54893 pubmed publisher
    ..The model fungus Aspergillus nidulans possesses two ?-1,3-glucan synthase (AGS) genes, agsA and agsB...
  78. Fukuda K, Yamada K, Deoka K, Yamashita S, Ohta A, Horiuchi H. Class III chitin synthase ChsB of Aspergillus nidulans localizes at the sites of polarized cell wall synthesis and is required for conidial development. Eukaryot Cell. 2009;8:945-56 pubmed publisher
    ..address these issues, we characterized the deletion mutant of a class III chitin synthase-encoding gene of Aspergillus nidulans, chsB, and investigated ChsB localization in the hyphae and conidiophores...
  79. Hagiwara D, Mizuno T, Abe K. Characterization of NikA histidine kinase and two response regulators with special reference to osmotic adaptation and asexual development in Aspergillus nidulans. Biosci Biotechnol Biochem. 2009;73:1566-71 pubmed
    b>Aspergillus nidulans has many histidine-to-aspartate (His-Asp) phosphorelay components, including 15 histidine kinases (HKs), four response regulators (RRs), and a histidine-containing phosphotransfer intermediate (HPt)...
  80. Vangelatos I, Vlachakis D, Sophianopoulou V, Diallinas G. Modelling and mutational evidence identify the substrate binding site and functional elements in APC amino acid transporters. Mol Membr Biol. 2009;26:356-70 pubmed publisher
  81. Bergmann S, Funk A, Scherlach K, Schroeckh V, Shelest E, Horn U, et al. Activation of a silent fungal polyketide biosynthesis pathway through regulatory cross talk with a cryptic nonribosomal peptide synthetase gene cluster. Appl Environ Microbiol. 2010;76:8143-9 pubmed publisher
    ..Screening secondary metabolite genes of the model fungus Aspergillus nidulans, we noted a silent gene cluster on chromosome II comprising two nonribosomal peptide synthetase (NRPS) ..
  82. Galindo A, Calcagno Pizarelli A, Arst H, Peñalva M. An ordered pathway for the assembly of fungal ESCRT-containing ambient pH signalling complexes at the plasma membrane. J Cell Sci. 2012;125:1784-95 pubmed publisher
    ..In Aspergillus nidulans, dedicated Pal proteins include the plasma membrane receptor PalH and its coupled arrestin, PalF, which ..
  83. Palmer J, Theisen J, Duran R, Grayburn W, Calvo A, Keller N. Secondary metabolism and development is mediated by LlmF control of VeA subcellular localization in Aspergillus nidulans. PLoS Genet. 2013;9:e1003193 pubmed publisher
    ..partner of VeA identified through a reverse genetics screen looking for LaeA-like methyltransferases in Aspergillus nidulans. One of the putative LaeA-like methyltransferases identified, LlmF, is a negative regulator of ..
  84. Bukhari E, Alrabiaah A. First case of extensive spinal cord infection with Aspergillus nidulans in a child with chronic granulomatous disease. J Infect Dev Ctries. 2009;3:321-3 pubmed
    ..The etiology of most common fungal infections in CGD are Aspergillus species. Aspergillus nidulans is one of several species of Aspergillus with low pathogenicity...
  85. Sanchez J, Chiang Y, Szewczyk E, Davidson A, Ahuja M, Elizabeth Oakley C, et al. Molecular genetic analysis of the orsellinic acid/F9775 gene cluster of Aspergillus nidulans. Mol Biosyst. 2010;6:587-93 pubmed publisher
    F-9775A and F-9775B are cathepsin K inhibitors that arise from a chromatin remodelling deletant strain of Aspergillus nidulans. A polyketide synthase gene has been determined to be responsible for their formation and for the simpler, ..
  86. Abreu C, Sanguinetti M, Amillis S, Ramon A. UreA, the major urea/H+ symporter in Aspergillus nidulans. Fungal Genet Biol. 2010;47:1023-33 pubmed publisher
    We report here the characterization of UreA, a high-affinity urea/H+ symporter of Aspergillus nidulans. The deletion of the encoding gene abolishes urea transport at low substrate concentrations, suggesting that in these conditions UreA ..
  87. Paul B, El Ganiny A, Abbas M, Kaminskyj S, Dahms T. Quantifying the importance of galactofuranose in Aspergillus nidulans hyphal wall surface organization by atomic force microscopy. Eukaryot Cell. 2011;10:646-53 pubmed publisher
    ..b>Aspergillus nidulans strains deleted for Galf biosynthesis enzymes UgeA (UDP-glucose-4-epimerase) and UgmA (UDP-galactopyranose ..
  88. Gifford D, Schoustra S, Kassen R. The length of adaptive walks is insensitive to starting fitness in Aspergillus nidulans. Evolution. 2011;65:3070-8 pubmed publisher
    ..Contrary to the gradualist view, we show that the length of adaptive walks in the fungus Aspergillus nidulans is insensitive to starting fitness and involves just two mutations on average...
  89. Gerke J, Bayram O, Braus G. Fungal S-adenosylmethionine synthetase and the control of development and secondary metabolism in Aspergillus nidulans. Fungal Genet Biol. 2012;49:443-54 pubmed publisher
    The filamentous fungus Aspergillus nidulans carries a single gene for the S-adenosylmethionine (SAM) synthetase SasA, whereas many other organisms possess multiple SAM synthetases...
  90. Alam M, El Ganiny A, Afroz S, Sanders D, Liu J, Kaminskyj S. Aspergillus nidulans galactofuranose biosynthesis affects antifungal drug sensitivity. Fungal Genet Biol. 2012;49:1033-43 pubmed publisher
    ..Strains with alcA(p)-mediated overexpression of ugeA and ugtA had lower caspofungin sensitivity. Galf appears to play an important role in A. nidulans growth and vigor...
  91. Oh Y, Ahn C, Kim J, Ro H, Lee C, Kim J. Proteomic analysis of early phase of conidia germination in Aspergillus nidulans. Fungal Genet Biol. 2010;47:246-53 pubmed publisher
    ..This study represents the first proteomic analysis of early phase of conidia germination and will contribute to a better understanding of the molecular events involved in conidia germination process...
  92. Garcia Pedrajas M, Baeza Montañez L, Gold S. Regulation of Ustilago maydis dimorphism, sporulation, and pathogenic development by a transcription factor with a highly conserved APSES domain. Mol Plant Microbe Interact. 2010;23:211-22 pubmed publisher
    ..Putative cis-acting regulatory sequences fitting the consensus binding site for the Aspergillus nidulans transcription factor StuA were identified in 13 of these genes...