acremonium

Summary

Summary: A mitosporic fungal genus with many reported ascomycetous teleomorphs. Cephalosporin antibiotics are derived from this genus.

Top Publications

  1. Beaudreuil S, Buchler M, Al Najjar A, Bastides F, Francois M, Duong T, et al. Acute septic arthritis after kidney transplantation due to Acremonium. Nephrol Dial Transplant. 2003;18:850-1 pubmed
  2. Poling S, Wicklow D, Rogers K, Gloer J. Acremonium zeae, a protective endophyte of maize, produces dihydroresorcylide and 7-hydroxydihydroresorcylides. J Agric Food Chem. 2008;56:3006-9 pubmed publisher
    b>Acremonium zeae has been characterized as a protective endophyte of maize and displays antifungal activity against other fungi. Pyrrocidines A and B were discovered to be the metabolites accounting for this activity...
  3. Evans L, Hedger J, Brayford D, Stavri M, Smith E, O Donnell G, et al. An antibacterial hydroxy fusidic acid analogue from Acremonium crotocinigenum. Phytochemistry. 2006;67:2110-4 pubmed
    ..16-deacetoxy-7-beta-hydroxy-fusidic acid (1), was isolated from a fermentation of the mitosporic fungus Acremonium crotocinigenum...
  4. Ratnayake R, Fremlin L, Lacey E, Gill J, Capon R. Acremolides A-D, lipodepsipeptides from an Australian marine-derived fungus, Acremonium sp. J Nat Prod. 2008;71:403-8 pubmed publisher
    An Australian estuarine isolate of an Acremonium sp...
  5. Fujii T, Iwata K, Murakami K, Yano S, Sawayama S. Isolation of uracil auxotrophs of the fungus Acremonium cellulolyticus and the development of a transformation system with the pyrF gene. Biosci Biotechnol Biochem. 2012;76:245-9 pubmed
    b>Acremonium cellulolyticus CF-2612 is a cellulase hyper-producing mutant that originated from A. cellulolyticus Y-94...
  6. Fang X, Yano S, Inoue H, Sawayama S. Strain improvement of Acremonium cellulolyticus for cellulase production by mutation. J Biosci Bioeng. 2009;107:256-61 pubmed publisher
    In the search for an efficient producer of cellulolytic enzymes, Acremonium cellulolyticus strain C-1 was subjected to mutagenesis using UV-irradiation and N-methyl-N'nitro-N-nitrosoguanidine (NTG) and strain CF-2612 was isolated...
  7. de Almeida M, Guimarães V, Falkoski D, Visser E, Siqueira G, Milagres A, et al. Direct ethanol production from glucose, xylose and sugarcane bagasse by the corn endophytic fungi Fusarium verticillioides and Acremonium zeae. J Biotechnol. 2013;168:71-7 pubmed publisher
    Production of ethanol with two corn endophytic fungi, Fusarium verticillioides and Acremonium zeae, was studied. The yield of ethanol from glucose, xylose and a mixture of both sugars were 0.47, 0.46 and 0.50g/g ethanol/sugar for F...
  8. Boot C, Tenney K, Valeriote F, Crews P. Highly N-methylated linear peptides produced by an atypical sponge-derived Acremonium sp. J Nat Prod. 2006;69:83-92 pubmed
    RHM1 (1) and RHM2 (2) are highly N-methylated linear octapeptides produced by an atypical strain of Acremonium sp., cultured from a marine sponge collected in Papua New Guinea...
  9. Bonnet M, Camares O, Veisseire P. Effects of zinc and influence of Acremonium lolii on growth parameters, chlorophyll a fluorescence and antioxidant enzyme activities of ryegrass (Lolium perenne L. cv Apollo). J Exp Bot. 2000;51:945-53 pubmed
    ..11.1.11; superoxide dismutase (SOD), EC 1.15.1.1) of ryegrass infected or not by Acremonium lolii, and treated with nutrient solution containing 0-50 mM ZnSO(4) were studied...

More Information

Publications79

  1. Huang C, Lai W, Lee M, Chen C, Vasella A, Tsai Y, et al. Crystal structure of glucooligosaccharide oxidase from Acremonium strictum: a novel flavinylation of 6-S-cysteinyl, 8alpha-N1-histidyl FAD. J Biol Chem. 2005;280:38831-8 pubmed
    Glucooligosaccharide oxidase from Acremonium strictum has been screened for potential applications in oligosaccharide acid production and alternative carbohydrate detection, because it catalyzes the oxidation of glucose, maltose, lactose, ..
  2. Ullan R, Godio R, Teijeira F, Vaca I, Garcia Estrada C, Feltrer R, et al. RNA-silencing in Penicillium chrysogenum and Acremonium chrysogenum: validation studies using beta-lactam genes expression. J Microbiol Methods. 2008;75:209-18 pubmed publisher
    ..double-stranded RNA expression cassette for gene silencing in the filamentous fungi Penicillium chrysogenum and Acremonium chrysogenum...
  3. Wu X, Fan K, Wang Q, Yang K. C-terminus mutations of Acremonium chrysogenum deacetoxy/deacetylcephalosporin C synthase with improved activity toward penicillin analogs. FEMS Microbiol Lett. 2005;246:103-10 pubmed
    Deacetoxy/deacetylcephalosporin C synthase (acDAOC/DACS) from Acremonium chrysogenum is a bifunctional enzyme that catalyzes both the ring-expansion of penicillin N to deacetoxycephalosporin C (DAOC) and the hydroxylation of the latter to ..
  4. Vescia N, Cavarischia R, Valente A, Fabiani M, Melchionda C, Mastroeni I. Case Report. Multiple etiology post-surgery endophthalmitis. Mycoses. 2002;45:41-4 pubmed
    ..infection was due to Staphylococcus aureus and three fungal components, Candida albicans, Candida glabrata and Acremonium kiliense, which were subsequently isolated...
  5. Nijland J, Kovalchuk A, van den Berg M, Bovenberg R, Driessen A. Expression of the transporter encoded by the cefT gene of Acremonium chrysogenum increases cephalosporin production in Penicillium chrysogenum. Fungal Genet Biol. 2008;45:1415-21 pubmed publisher
    By introduction of the cefEF genes of Acremonium chrysogenum and the cmcH gene of Streptomyces clavuligerus, Penicillium chrysogenum can be reprogrammed to form adipoyl-7-amino-3-carbamoyloxymethyl-3-cephem-4-carboxylic acid (ad7-ACCCA), ..
  6. Degenkolb T, Heinze S, Schlegel B, Strobel G, Grafe U. Formation of new lipoaminopeptides, acremostatins A, B, and C, by co-cultivation of Acremonium sp. Tbp-5 and Mycogone rosea DSM 12973. Biosci Biotechnol Biochem. 2002;66:883-6 pubmed
    Formation of new lipoaminopeptides, acremostatins A, B, and C, was observed during co-cultivation of Acremonium sp. Tbp-5 and Mycogone rosea DSM 12973...
  7. Dreyer J, Eichhorn H, Friedlin E, Kürnsteiner H, Kück U. A homologue of the Aspergillus velvet gene regulates both cephalosporin C biosynthesis and hyphal fragmentation in Acremonium chrysogenum. Appl Environ Microbiol. 2007;73:3412-22 pubmed
    ..We have identified the veA homologue AcveA from Acremonium chrysogenum, the major producer of the beta-lactam antibiotic cephalosporin C...
  8. Ullán R, Liu G, Casqueiro J, Gutierrez S, Banuelos O, Martin J. The cefT gene of Acremonium chrysogenum C10 encodes a putative multidrug efflux pump protein that significantly increases cephalosporin C production. Mol Genet Genomics. 2002;267:673-83 pubmed
    ..gene (which encodes the alpha-aminoadipyl-cysteinyl-valine synthetase involved in cephalosporin synthesis) of Acremonium chrysogenum revealed the presence of two different transcripts corresponding to two new ORFs...
  9. Evers M, Trip H, van den Berg M, Bovenberg R, Driessen A. Compartmentalization and transport in beta-lactam antibiotics biosynthesis. Adv Biochem Eng Biotechnol. 2004;88:111-35 pubmed
    ..This compartmentalization also requires specific membrane transport steps of which the details are currently uncovered. ..
  10. Summerbell R, Schroers H. Analysis of phylogenetic relationship of Cylindrocarpon lichenicola and Acremonium falciforme to the Fusarium solani species complex and a review of similarities in the spectrum of opportunistic infections caused by these fungi. J Clin Microbiol. 2002;40:2866-75 pubmed
    ..affinities of two well-known tropical fungal opportunistic pathogens, Cylindrocarpon lichenicola and Acremonium falciforme, to members of the Fusarium solani species complex. C. lichenicola and A...
  11. Park E, Naruse K, Kato T. Improvement of cellulase production in cultures of Acremonium cellulolyticus using pretreated waste milk pack with cellulase targeting for biorefinery. Bioresour Technol. 2011;102:6120-7 pubmed publisher
    Cellulase production in cultures of Acremonium cellulolyticus was significantly improved by using waste milk pack (MP) that had been pretreated with cellulase...
  12. Huang C, Winkler A, Chen C, Lai W, Tsai Y, Macheroux P, et al. Functional roles of the 6-S-cysteinyl, 8alpha-N1-histidyl FAD in glucooligosaccharide oxidase from Acremonium strictum. J Biol Chem. 2008;283:30990-6 pubmed publisher
    The crystal structure of glucooligosaccharide oxidase from Acremonium strictum was demonstrated to contain a bicovalent flavinylation, with the 6- and 8alpha-positions of the flavin isoalloxazine ring cross-linked to Cys(130) and His(70), ..
  13. Schmitt E, Hoff B, Kück U. Regulation of cephalosporin biosynthesis. Adv Biochem Eng Biotechnol. 2004;88:1-43 pubmed
    The filamentous fungus Acremonium chrysogenum is the natural producer of the beta-lactam antibiotic cephalosporin C and is as such used worldwide in major biotechnical applications...
  14. Rodríguez Sáiz M, Lembo M, Bertetti L, Muraca R, Velasco J, Malcangi A, et al. Strain improvement for cephalosporin production by Acremonium chrysogenum using geneticin as a suitable transformation marker. FEMS Microbiol Lett. 2004;235:43-9 pubmed
    An Acremonium chrysogenum strain improvement program based on the transformation with cephalosporin biosynthetic genes was carried out to enhance cephalosporin C production...
  15. Afiyatullov S, Kalinovsky A, Pivkin M, Dmitrenok P, Kuznetsova T. New diterpene glycosides of the fungus Acremonium striatisporum isolated from a sea cucumber. Nat Prod Res. 2006;20:902-8 pubmed
    Three new diterpene glycosides, virescenosides V (1), W (2), and X (3) have been isolated from a marine strain of Acremonium striatisporum KMM 4401 associated with the holothurian Eupentacta fraudatrix...
  16. Ikeda Y, Hayashi H, Okuda N, Park E. Efficient cellulase production by the filamentous fungus Acremonium cellulolyticus. Biotechnol Prog. 2007;23:333-8 pubmed
    Cellulase production was investigated in a culture of a strain of Acremonium cellulolyticus. The medium components were optimized for the improvement of cellulase production...
  17. Cornejo Juárez P, Velásquez Acosta C, Martínez Roque V, Rangel Cordero A, Volkow Fernández P. [Asymptomatic fungemia caused by Acremonium sp associated with colonization of a central venous catheter]. Gac Med Mex. 2007;143:193-6 pubmed
    ..Microorganisms considered saprophytes have emerged as invasive or indolent pathogens among immuno-compromised patients...
  18. Liu C, Matsushita Y, Shimizu K, Makimura K, Hasumi K. Activation of prothrombin by two subtilisin-like serine proteases from Acremonium sp. Biochem Biophys Res Commun. 2007;358:356-62 pubmed
    ..serine proteases (AS-E1 and -E2) that activate prothrombin have been identified in a culture of the fungus Acremonium sp. The enzymes were purified through repeated hydrophobic interaction chromatography...
  19. Kosalkova K, Marcos A, Martin J. A moderate amplification of the mecB gene encoding cystathionine-gamma-lyase stimulates cephalosporin biosynthesis in Acremonium chrysogenum. J Ind Microbiol Biotechnol. 2001;27:252-8 pubmed
    ..By amplification of the mecB gene in Acremonium chrysogenum C10, several transformants were obtained that produced 10-40% higher levels of cephalosporin...
  20. Geyer A, Fox L, Husain S, Della Latta P, Grossman M. Acremonium mycetoma in a heart transplant recipient. J Am Acad Dermatol. 2006;55:1095-100 pubmed
    ..We describe a case of eumycetoma in a cardiac transplant recipient caused by the soil saprophyte Acremonium species. This represents only the fifth case of eumycetoma reported in a solid organ transplant recipient...
  21. Das S, Saha R, Dar S, Ramachandran V. Acremonium species: a review of the etiological agents of emerging hyalohyphomycosis. Mycopathologia. 2010;170:361-75 pubmed publisher
    ..Subcutaneous and invasive fungal infection due to the emerging hyalohyphomycotic fungus, Acremonium, has drawn the attention of clinicians and microbiologists, as a potential pathogen in patients with and without ..
  22. Cretì A, Esposito V, Bocchetti M, Baldi G, De Rosa P, Parrella R, et al. Voriconazole curative treatment for Acremonium species keratitis developed in a patient with concomitant Staphylococcus aureus corneal infection: a case report. In Vivo. 2006;20:169-71 pubmed
    ..A combined Acremonium spp. and S. aureus infection was detected. After unsuccessful therapy with fluconazole, the Acremonium spp...
  23. Pöggeler S, Hoff B, Kück U. Asexual cephalosporin C producer Acremonium chrysogenum carries a functional mating type locus. Appl Environ Microbiol. 2008;74:6006-16 pubmed publisher
    b>Acremonium chrysogenum, the fungal producer of the pharmaceutically relevant beta-lactam antibiotic cephalosporin C, is classified as asexual because no direct observation of mating or meiosis has yet been reported...
  24. Novicki T, LaFe K, Bui L, Bui U, Geise R, Marr K, et al. Genetic diversity among clinical isolates of Acremonium strictum determined during an investigation of a fatal mycosis. J Clin Microbiol. 2003;41:2623-8 pubmed
    Primarily saprophytic in nature, fungi of the genus Acremonium are a well-documented cause of mycetoma and other focal diseases. More recently, a number of Acremonium spp...
  25. Kallow W, Neuhof T, Arezi B, Jungblut P, von Dohren H. Penicillin biosynthesis: intermediates of biosynthesis of delta-L-alpha-aminoadipyl-L-cysteinyl-D-valine formed by ACV synthetase from Acremonium chrysogenum. FEBS Lett. 1997;414:74-8 pubmed
    ..We conclude that the first peptide bond is formed between delta-carboxyl of L-aminoadipic acid and L-cysteine, followed by addition of the dipeptidyl intermediate to L-valine...
  26. de Almeida M, Guimarães V, Bischoff K, Falkoski D, Pereira O, Gonçalves D, et al. Cellulases and hemicellulases from endophytic Acremonium species and its application on sugarcane bagasse hydrolysis. Appl Biochem Biotechnol. 2011;165:594-610 pubmed publisher
    The aim of this work was to have cellulase activity and hemicellulase activity screenings of endophyte Acremonium species (Acremonium zeae EA0802 and Acremonium sp. EA0810)...
  27. Park E, Michinaka A, Okuda N. Enzymatic hydrolysis of waste office paper using viscosity as operating parameter. Biotechnol Prog. 2001;17:379-82 pubmed
    ..Therefore, the RS concentration from this hydrolysis process feeding WO paper using apparent viscosity as operating parameter may be of sufficient concentration to serve as a carbon source in microorganism culture or chemical feedstock...
  28. Scott I, Flynn H, Miller D. Delayed-onset endophthalmitis following cataract surgery caused by Acremonium strictum. Ophthalmic Surg Lasers Imaging. 2005;36:506-7 pubmed
    This case represents the first report of Acremonium strictum endophthalmitis. Endophthalmitis caused by A...
  29. Liu Y, Gong G, Xie L, Yuan N, Zhu C, Zhu B, et al. Improvement of cephalosporin C production by recombinant DNA integration in Acremonium chrysogenum. Mol Biotechnol. 2010;44:101-9 pubmed publisher
    ..3%. This was the first report that three or more genes were introduced simultaneously into A. chrysogenum. Our results also demonstrated that the combination of these genes had a synergy effect in a CPC high producer...
  30. Jayus -, McDougall B, Seviour R. Purification and characterization of the (1-->3)-beta-glucanases from Acremonium sp. IMI 383068. FEMS Microbiol Lett. 2004;230:259-64 pubmed
    Three extracellular (1-->3)-beta-glucanases were purified from the fungus Acremonium sp. IMI 383068...
  31. Wicklow D, Roth S, Deyrup S, Gloer J. A protective endophyte of maize: Acremonium zeae antibiotics inhibitory to Aspergillus flavus and Fusarium verticillioides. Mycol Res. 2005;109:610-8 pubmed
    The maize endophyte Acremonium zeae is antagonistic to kernel rotting and mycotoxin producing fungi Aspergillus flavus and Fusarium verticillioides in cultural tests for antagonism, and interferes with A...
  32. Wicklow D, Poling S. Antimicrobial activity of pyrrocidines from Acremonium zeae against endophytes and pathogens of maize. Phytopathology. 2009;99:109-15 pubmed publisher
    b>Acremonium zeae produces pyrrocidines A and B, which are polyketide-amino acid-derived antibiotics, and is recognized as a seedborne protective endophyte of maize which augments host defenses against microbial pathogens causing seedling ..
  33. Prasetyo J, Sumita S, Okuda N, Park E. Response of cellulase activity in pH-controlled cultures of the filamentous fungus Acremonium cellulolyticus. Appl Biochem Biotechnol. 2010;162:52-61 pubmed publisher
    Cellulase production was investigated in pH-controlled cultures of Acremonium cellulolyticus. The response to culture pH was investigated for three cellulolytic enzymes, carbomethyl cellulase (CMCase), avicelase, and beta-glucosidase...
  34. Fang X, Yano S, Inoue H, Sawayama S. Lactose enhances cellulase production by the filamentous fungus Acremonium cellulolyticus. J Biosci Bioeng. 2008;106:115-20 pubmed publisher
    b>Acremonium cellulolyticus is a fungus that produces cellulase and has been exploited by enzyme industry. To promote cellulase production by A...
  35. Joe S, Lim J, Lee J, Yoon Y. Case report of Acremonium intraocular infection after cataract extraction. Korean J Ophthalmol. 2010;24:119-22 pubmed publisher
    ..acne) endophthalmitis. As a result of the smear and culture of the vitreous fluid identified as an Acremonium species, she was treated with intravenous amphotericin B injections for five days, followed by oral voriconazole ..
  36. Perdomo H, Sutton D, Garcia D, Fothergill A, Cano J, Gene J, et al. Spectrum of clinically relevant Acremonium species in the United States. J Clin Microbiol. 2011;49:243-56 pubmed publisher
    Some species in the polyphyletic fungal genus Acremonium are important opportunist pathogens...
  37. Andersson M, Mikkola R, Raulio M, Kredics L, Maijala P, Salkinoja Salonen M. Acrebol, a novel toxic peptaibol produced by an Acremonium exuviarum indoor isolate. J Appl Microbiol. 2009;106:909-23 pubmed publisher
    ..To identify a toxin and its producer isolated from woody material in a building where the occupants experienced serious ill health symptoms...
  38. Hideno A, Inoue H, Tsukahara K, Yano S, Fang X, Endo T, et al. Production and characterization of cellulases and hemicellulases by Acremonium cellulolyticus using rice straw subjected to various pretreatments as the carbon source. Enzyme Microb Technol. 2011;48:162-8 pubmed publisher
    ..and commercial cellulose, Solka Floc (SF), were used as carbon sources for cellulase production by the fungus Acremonium cellulolyticus...
  39. Inoue H, Fujii T, Yoshimi M, Taylor L, Decker S, Kishishita S, et al. Construction of a starch-inducible homologous expression system to produce cellulolytic enzymes from Acremonium cellulolyticus. J Ind Microbiol Biotechnol. 2013;40:823-30 pubmed publisher
    A starch-inducible homologous expression system in Acremonium cellulolyticus was constructed to successfully produce recombinant cellulolytic enzymes. A...
  40. Lotfy W. The utilization of beet molasses as a novel carbon source for cephalosporin C production by Acremonium chrysogenum: Optimization of process parameters through statistical experimental designs. Bioresour Technol. 2007;98:3491-8 pubmed
    ..work, cephalosporin C (CPC) production on pilot scale fermenters of 600l capacity with 350l working volume by Acremonium chrysogenum EMCC 904 was performed...
  41. Schmitt E, Kempken R, Kuck U. Functional analysis of promoter sequences of cephalosporin C biosynthesis genes from Acremonium chrysogenum: specific DNA-protein interactions and characterization of the transcription factor PACC. Mol Genet Genomics. 2001;265:508-18 pubmed
    An analysis of the pcbC promoter from the cephalosporin C-producing filamentous fungus Acremonium chrysogenum was performed using fungal transformants carrying reporter gene fusions...
  42. Pastorino A, Menezes U, Marques H, Vallada M, Cappellozi V, Carnide E, et al. Acremonium kiliense infection in a child with chronic granulomatous disease. Braz J Infect Dis. 2005;9:529-34 pubmed
    ..We report on a four-month-old child with pneumonia caused by the fungus Acremonium kiliense as the first clinical manifestation of chronic granulomatous disease...
  43. Schroers H, Geldenhuis M, Wingfield M, Schoeman M, Yen Y, Shen W, et al. Classification of the guava wilt fungus Myxosporium psidii, the palm pathogen Gliocladium vermoesenii and the persimmon wilt fungus Acremonium diospyri in Nalanthamala. Mycologia. 2005;97:375-95 pubmed
    ..another undescribed anamorphic species from palm, two species of Rubrinectria and the persimmon pathogen Acremonium diospyri are monophyletic and belong to the Nectriaceae (Hypocreales) based on partial nuclear large subunit ..
  44. Afiyatullov S, Kalinovsky A, Kuznetsova T, Pivkin M, Prokof eva N, Dmitrenok P, et al. New glycosides of the fungus Acremonium striatisporum isolated from a sea cucumber. J Nat Prod. 2004;67:1047-51 pubmed
    ..diterpene glycosides, virescenosides R (1), S (2), T (3), and U (4), have been isolated from a marine strain of Acremonium striatisporum KMM 4401 associated with the holothurian Eupentacta fraudatrix...
  45. Teijeira F, Ullan R, Guerra S, Garcia Estrada C, Vaca I, Martin J. The transporter CefM involved in translocation of biosynthetic intermediates is essential for cephalosporin production. Biochem J. 2009;418:113-24 pubmed publisher
    The cluster of early cephalosporin biosynthesis genes (pcbAB, pcbC, cefD1, cefD2 and cefT of Acremonium chrysogenum) contains all of the genes required for the biosynthesis of the cephalosporin biosynthetic pathway intermediate penicillin ..
  46. Kim B, Kim S, Yang D. Cybernetic modeling of the cephalosporin C fermentation process by Cephalosporium acremonium. Biotechnol Lett. 2003;25:611-6 pubmed
    ..It could be a useful tool to optimize the production of cephalosporin C by Cephalosporium acremonium in batch, fed-batch or continuous operations.
  47. Ullan R, Casqueiro J, Banuelos O, Fernandez F, Gutierrez S, Martin J. A novel epimerization system in fungal secondary metabolism involved in the conversion of isopenicillin N into penicillin N in Acremonium chrysogenum. J Biol Chem. 2002;277:46216-25 pubmed
    ..This epimerization system occurs in eukaryotic cells and is entirely different from the known epimerization systems involved in the biosynthesis of bacterial beta-lactam antibiotics...
  48. Zhang P, Bao B, Dang H, Hong J, Lee H, Yoo E, et al. Anti-inflammatory sesquiterpenoids from a sponge-derived Fungus Acremonium sp. J Nat Prod. 2009;72:270-5 pubmed publisher
    In the course of our search for bioactive metabolites from a sponge-derived fungus Acremonium sp., new sesquiterpenoids (1-4) were isolated along with known derivatives by bioactivity-guided fractionation...
  49. Krishnaveni R, Rathod V, Thakur M, Neelgund Y. Transformation of L-tyrosine to L-dopa by a novel fungus, Acremonium rutilum, under submerged fermentation. Curr Microbiol. 2009;58:122-8 pubmed publisher
    The present study deals with the transformation of L-tyrosine to L-dopa by Acremonium rutilum, a fungal tyrosinase producer, isolated from decomposed banana stud. This appears to be the first report on A...
  50. Liu G, Casqueiro J, Banuelos O, Cardoza R, Gutierrez S, Martin J. Targeted inactivation of the mecB gene, encoding cystathionine-gamma-lyase, shows that the reverse transsulfuration pathway is required for high-level cephalosporin biosynthesis in Acremonium chrysogenum C10 but not for methionine induction of the ce. J Bacteriol. 2001;183:1765-72 pubmed
    Targeted gene disruption efficiency in Acremonium chrysogenum was increased 10-fold by applying the double-marker enrichment technique to this filamentous fungus...
  51. Lee M, Lai W, Lin S, Hsu C, Liaw S, Tsai Y. Structural characterization of glucooligosaccharide oxidase from Acremonium strictum. Appl Environ Microbiol. 2005;71:8881-7 pubmed
    Glucooligosaccharide oxidase from Acremonium strictum was screened for potential applications in oligosaccharide acid production and carbohydrate detection...
  52. Ullan R, Teijeira F, Martin J. Expression of the Acremonium chrysogenum cefT gene in Penicillum chrysogenum indicates that it encodes an hydrophilic beta-lactam transporter. Curr Genet. 2008;54:153-61 pubmed publisher
    The Acremonium chryrsogenum cefT gene encoding a membrane protein of the major facilitator superfamily implicated in the cephalosporin biosynthesis in A...
  53. Zapotoczny S, Jurkiewicz A, Tylko G, Anielska T, Turnau K. Accumulation of copper by Acremonium pinkertoniae, a fungus isolated from industrial wastes. Microbiol Res. 2007;162:219-28 pubmed
    b>Acremonium pinkertoniae isolated from zinc wastes was studied to understand the mechanisms that allow living organisms to thrive in polluted environments and the possible role of the fungus in the redistribution and cycling of copper...
  54. Ullan R, Campoy S, Casqueiro J, Fernandez F, Martin J. Deacetylcephalosporin C production in Penicillium chrysogenum by expression of the isopenicillin N epimerization, ring expansion, and acetylation genes. Chem Biol. 2007;14:329-39 pubmed
    ..We have constructed P. chrysogenum strains expressing cefD1, cefD2, cefEF, and cefG genes cloned from Acremonium chrysogenum. Northern analysis revealed that the four genes were expressed in P. chrysogenum...
  55. Goswami J, Pandey R, Tewari J, Goswami B. Management of root knot nematode on tomato through application of fungal antagonists, Acremonium strictum and Trichoderma harzianum. J Environ Sci Health B. 2008;43:237-40 pubmed publisher
    Management of root knot nematode disease infecting tomato, by the use of fungal bioagents Acremonium strictum and Trichoderma harzianum isolated from egg masses of M. incognita infecting tomato has been carried out...
  56. Marcos A, Kosalkova K, Cardoza R, Fierro F, Gutierrez S, Martin J. Characterization of the reverse transsulfuration gene mecB of Acremonium chrysogenum, which encodes a functional cystathionine-gamma-lyase. Mol Gen Genet. 2001;264:746-54 pubmed
    In Acremonium chrysogenum, biosynthesis of cysteine for the formation of cephalosporin has been proposed to occur through the reverse transsulfuration pathway. A gene, named mecB, has been cloned from an A...
  57. Hijarrubia M, Aparicio J, Casqueiro J, Martin J. Characterization of the lys2 gene of Acremonium chrysogenum encoding a functional alpha-aminoadipate activating and reducing enzyme. Mol Gen Genet. 2001;264:755-62 pubmed
    A 5.2-kb NotI DNA fragment isolated from a genomic library of Acremonium chrysogenum by hybridization with a probe internal to the Penicillium chrysogenum lys2 gene, was able to complement an alpha-aminoadipate reductase-deficient mutant ..
  58. Schmitt E, Bunse A, Janus D, Hoff B, Friedlin E, Kürnsteiner H, et al. Winged helix transcription factor CPCR1 is involved in regulation of beta-lactam biosynthesis in the fungus Acremonium chrysogenum. Eukaryot Cell. 2004;3:121-34 pubmed
    ..were used to determine the functional role of the RFX transcription factor CPCR1 from the filamentous fungus Acremonium chrysogenum in cephalosporin C biosynthesis...
  59. Alfonso J, Baamonde M, Santos M, Astudillo A, Fernandez Vega L. Acremonium fungal infection in 4 patients after laser in situ keratomileusis. J Cataract Refract Surg. 2004;30:262-7 pubmed
    ..A study of the corneas demonstrated the presence of the fungus Acremonium in all cases. Rigid asepsis during the surgical procedure is important to prevent this serious complication.
  60. Park E, Anh P, Okuda N. Bioconversion of waste office paper to L(+)-lactic acid by the filamentous fungus Rhizopus oryzae. Bioresour Technol. 2004;93:77-83 pubmed
    ..This indicates that the production rate may be inhibited by xylose derived from hemicellulose, and the yield may be inhibited by unknown compounds derived from paper pulp...
  61. Calderaro A, Motta F, Larini S, Gorrini C, Martinelli M, Piscopo G, et al. Two rare cases of Acremonium acute endophthalmitis after cataract surgery in a tertiary care hospital. New Microbiol. 2013;36:427-31 pubmed
    This report describes two cases of Acremonium sp. endophthalmitis, occurring in two patients who underwent cataract surgery on the same day in the same operating room of our hospital ophthalmology clinic...
  62. Afiyatullov S, Kalinovsky A, Kuznetsova T, Isakov V, Pivkin M, Dmitrenok P, et al. New diterpene glycosides of the fungus Acremonium striatisporum isolated from a sea cucumber. J Nat Prod. 2002;65:641-4 pubmed
    ..Three new diterpene glycosides, virescenosides O (1), P (2), and Q (3), have been isolated from a marine strain of Acremonium striatisporum KMM 4401 associated with the holothurian Eupentacta fraudatrix...
  63. Hoff B, Kück U. Use of bimolecular fluorescence complementation to demonstrate transcription factor interaction in nuclei of living cells from the filamentous fungus Acremonium chrysogenum. Curr Genet. 2005;47:132-8 pubmed
    ..interaction of the transcription factors AcFKH1 and CPCR1 in living cells from the filamentous fungus Acremonium chrysogenum...
  64. Suciati -, Fraser J, Lambert L, Pierens G, Bernhardt P, Garson M. Secondary metabolites of the sponge-derived fungus Acremonium persicinum. J Nat Prod. 2013;76:1432-40 pubmed publisher
    ..O (6), P (7), Q (8), and R (9), together with the known acremines A (1), F (2), and N (3) from the fungus Acremonium persicinum cultured from the marine sponge Anomoianthella rubra...
  65. Liu L, Long L, An Y, Yang J, Xu X, Hu C, et al. The thioredoxin reductase-encoding gene ActrxR1 is involved in the cephalosporin C production of Acremonium chrysogenum in methionine-supplemented medium. Appl Microbiol Biotechnol. 2013;97:2551-62 pubmed publisher
    ..Based on the genomic sequence, a thioredoxin reductase-encoding gene (ActrxR1) was isolated from Acremonium chrysogenum CGMCC3.3795...
  66. Bloemendal S, Loper D, Terfehr D, Kopke K, Kluge J, Teichert I, et al. Tools for advanced and targeted genetic manipulation of the ?-lactam antibiotic producer Acremonium chrysogenum. J Biotechnol. 2014;169:51-62 pubmed publisher
    b>Acremonium chrysogenum is the major producer of the ?-lactam antibiotic cephalosporin C and therefore of great importance for the pharmaceutical industry...
  67. Haddad R, El Mollayess G. Combination of intracameral and intrastromal voriconazole in the treatment of recalcitrant Acremonium fungal keratitis. Middle East Afr J Ophthalmol. 2012;19:265-8 pubmed publisher
    We present a report of a 28-year-old female with fungal keratitis due to Acremonium that was unresponsive to full medical therapy over 3 weeks...
  68. Bischoff K, Wicklow D, Jordan D, de Rezende S, Liu S, Hughes S, et al. Extracellular hemicellulolytic enzymes from the maize endophyte Acremonium zeae. Curr Microbiol. 2009;58:499-503 pubmed publisher
    ..The maize endophyte Acremonium zeae was surveyed for production of extracellular enzymes that hydrolyze cellulose and hemicellulose...
  69. Mattei D, Mordini N, Lo Nigro C, Gallamini A, Osenda M, Pugno F, et al. Successful treatment of Acremonium fungemia with voriconazole. Mycoses. 2003;46:511-4 pubmed
    We report two cases of Acremonium fungemia with proven involvement of the skin and probably of the lung in patients who were both undergoing chemotherapy, one for mantle cell lymphoma and the other for acute lymphoblastic leukemia...
  70. Rodriguez Ares T, De Rojas Silva V, Ferreiros M, Becerra E, Tome C, Sanchez Salorio M. Acremonium keratitis in a patient with herpetic neurotrophic corneal disease. Acta Ophthalmol Scand. 2000;78:107-9 pubmed
    Fungi belonging to the genus Acremonium Link ex Fries 1821 are ubiquitous environmental contaminants and soil saprophytes, but are infrequent pathogens in humans...