agaricus

Summary

Summary: A basidiomycetous fungal genus of the family Agaricaceae, order Agaricales, which includes the field mushroom (A. campestris) and the commercial mushroom (A. bisporus).

Top Publications

  1. Gonçalves J, Roma E, Gomes Santos A, Aguilar E, Cisalpino D, Fernandes L, et al. Pro-inflammatory effects of the mushroom Agaricus blazei and its consequences on atherosclerosis development. Eur J Nutr. 2012;51:927-37 pubmed publisher
    Extracts of the mushroom Agaricus blazei (A. blazei) have been described as possessing immunomodulatory and potentially cancer-protective activities. However, these effects of A...
  2. Carneiro A, Ferreira I, Dueñas M, Barros L, Da Silva R, Gomes E, et al. Chemical composition and antioxidant activity of dried powder formulations of Agaricus blazei and Lentinus edodes. Food Chem. 2013;138:2168-73 pubmed publisher
    ..b>Agaricus blazei and Lentinus edodes are among the most studied species all over the world, but those studies focused on ..
  3. Akiyama H, Endo M, Matsui T, Katsuda I, Emi N, Kawamoto Y, et al. Agaritine from Agaricus blazei Murrill induces apoptosis in the leukemic cell line U937. Biochim Biophys Acta. 2011;1810:519-25 pubmed publisher
    b>Agaricus blazei Murrill (ABM) has been shown to exhibit immunostimulatory and anti-cancer activities; however, its mechanism of action is poorly understood...
  4. Wagemaker M, Eastwood D, van der Drift C, Jetten M, Burton K, Van Griensven L, et al. Expression of the urease gene of Agaricus bisporus: a tool for studying fruit body formation and post-harvest development. Appl Microbiol Biotechnol. 2006;71:486-92 pubmed
    Fruit body initials of Agaricus bisporus contain high levels of urea, which decrease in the following developmental stages until stage 4 (harvest) when urea levels increase again...
  5. Geml J, Laursen G, Taylor D. Molecular diversity assessment of arctic and boreal Agaricus taxa. Mycologia. 2008;100:577-89 pubmed
    We provide a phylogenetic diversity assessment study in genus Agaricus as part of our ongoing work to saturate ITS and LSU rDNA sequence diversity of soil-dwelling fungi in Alaska...
  6. Jeong S, Koyyalamudi S, Jeong Y, Song C, Pang G. Macrophage immunomodulating and antitumor activities of polysaccharides isolated from Agaricus bisporus white button mushrooms. J Med Food. 2012;15:58-65 pubmed publisher
    b>Agaricus bisporus white button mushroom (WBM) is widely consumed in most countries for its culinary properties. Recently, its dietary intake has been shown to protect against breast cancer...
  7. Graf M, Bren U, Haltrich D, Oostenbrink C. Molecular dynamics simulations give insight into D-glucose dioxidation at C2 and C3 by Agaricus meleagris pyranose dehydrogenase. J Comput Aided Mol Des. 2013;27:295-304 pubmed publisher
    The flavin-dependent sugar oxidoreductase pyranose dehydrogenase (PDH) from the plant litter-degrading fungus Agaricus meleagris oxidizes D-glucose (GLC) efficiently at positions C2 and C3...
  8. Liu G, Wang X. Optimization of critical medium components using response surface methodology for biomass and extracellular polysaccharide production by Agaricus blazei. Appl Microbiol Biotechnol. 2007;74:78-83 pubmed
    Response surface methodology (RSM) was applied to optimize the critical medium ingredients of Agaricus blazei...
  9. Foulongne Oriol M, Murat C, Castanera R, Ramirez L, Sonnenberg A. Genome-wide survey of repetitive DNA elements in the button mushroom Agaricus bisporus. Fungal Genet Biol. 2013;55:6-21 pubmed publisher
    ..to describe tandem repeats and transposable elements distribution in the genome of the button mushroom, Agaricus bisporus. Transposable elements comprised 12...

More Information

Publications131 found, 100 shown here

  1. Nagaokaa M, Nagaoka H, Kondo K, Akiyama H, Maitani T. Measurement of a genotoxic hydrazine, agaritine, and its derivatives by HPLC with fluorescence derivatization in the agaricus mushroom and its products. Chem Pharm Bull (Tokyo). 2006;54:922-4 pubmed
    b>Agaricus blazei MURRILL mushroom products are sold as so-called health foods in Japan. However, a part of Agaricus is known to contain hydrazines...
  2. Chen S, Oh S, Phung S, Hur G, Ye J, Kwok S, et al. Anti-aromatase activity of phytochemicals in white button mushrooms (Agaricus bisporus). Cancer Res. 2006;66:12026-34 pubmed
    White button mushrooms (Agaricus bisporous) are a potential breast cancer chemopreventive agent, as they suppress aromatase activity and estrogen biosynthesis...
  3. Kerrigan R. Agaricus subrufescens, a cultivated edible and medicinal mushroom, and its synonyms. Mycologia. 2005;97:12-24 pubmed
    b>Agaricus subrufescens Peck was cultivated first in the late 1800s in eastern North America. The type consists partly of cultivated material and partly of field-collected specimens...
  4. Kuroiwa Y, Nishikawa A, Imazawa T, Kanki K, Kitamura Y, Umemura T, et al. Lack of subchronic toxicity of an aqueous extract of Agaricus blazei Murrill in F344 rats. Food Chem Toxicol. 2005;43:1047-53 pubmed
    b>Agaricus blazei Murrill, an edible mushroom, is widely used as a functional food due to its possible medicinal effects. Aqueous extracts are also used as food additive to provide an agreeable bitter taste...
  5. Takimoto H, Kato H, Kaneko M, Kumazawa Y. Amelioration of skewed Th1/Th2 balance in tumor-bearing and asthma-induced mice by oral administration of Agaricus blazei extracts. Immunopharmacol Immunotoxicol. 2008;30:747-60 pubmed
    We showed in a previous study that hot-water extracts of Agaricus blazei (Agaricus extracts) had anti-tumor activity to Meth A fibrosarcoma, but it remains unclear whether the Agaricus extracts ameliorate the skewed balance of type-1 T ..
  6. Singh R, Zhang Y, Nguyen N, Jeya M, Lee J. Covalent immobilization of ?-1,4-glucosidase from Agaricus arvensis onto functionalized silicon oxide nanoparticles. Appl Microbiol Biotechnol. 2011;89:337-44 pubmed publisher
    An efficient ?-1,4-glucosidase (BGL) secreting strain, Agaricus arvensis, was isolated and identified. The relative molecular weight of the purified A...
  7. Chen L, Shao H, Su Y. Coimmunization of Agaricus blazei Murill extract with hepatitis B virus core protein through DNA vaccine enhances cellular and humoral immune responses. Int Immunopharmacol. 2004;4:403-9 pubmed
    DNA vaccines induce protective humoral and cell-mediated immune responses in several animal models. Agaricus blazei Murill (ABM) is particularly rich in polysaccharides, and has shown particularly strong results in treating and preventing ..
  8. Smith J, Challen M, White P, Edmondson R, Chandler D. Differential effect of Agaricus host species on the population development of Megaselia halterata (Diptera: Phoridae). Bull Entomol Res. 2006;96:565-71 pubmed
    Twelve isolates from the genus Agaricus (Fungi, Basidiomycota) were investigated for their ability to support development of the phorid fly, Megaselia halterata (Wood), which is an important pest of the commercial white button mushroom ..
  9. Yamanaka D, Tada R, Adachi Y, Ishibashi K, Motoi M, Iwakura Y, et al. Agaricus brasiliensis-derived ?-glucans exert immunoenhancing effects via a dectin-1-dependent pathway. Int Immunopharmacol. 2012;14:311-9 pubmed publisher
    b>Agaricus brasiliensis is a well-known medicinal mushroom. We have previously demonstrated that Agaricus-derived polysaccharides exhibit potent antitumor effects; however, the underlying mechanism(s) have not been elucidated yet...
  10. Borovicka J, Kotrba P, Gryndler M, Mihaljevic M, Randa Z, Rohovec J, et al. Bioaccumulation of silver in ectomycorrhizal and saprobic macrofungi from pristine and polluted areas. Sci Total Environ. 2010;408:2733-44 pubmed publisher
    ..Standardized EDTA extraction of Ag in both the investigated soil profiles showed relatively low Ag extractibility, generally within the range of 2.2-7.7% of total Ag content. ..
  11. Stadler M, Hellwig V, Mayer Bartschmid A, Denzer D, Wiese B, Burkhardt N. Novel analgesic triglycerides from cultures of Agaricus macrosporus and other basidiomycetes as selective inhibitors of neurolysin. J Antibiot (Tokyo). 2005;58:775-86 pubmed
    ..They are produced in cultures of the edible mushroom, Agaricus macrosporus, and several other basidiomycetes of the genera Agaricus, Hypholoma, Psathyrella and Stropharia...
  12. Romaine C, Schlagnhaufer C. Mushroom (Agaricus bisporus). Methods Mol Biol. 2006;344:453-63 pubmed
    We have devised an easy and effective genetic transformation method for the preeminent edible mushroom, Agaricus bisporus...
  13. Simon R, Phillips K, Horst R, Munro I. Vitamin D mushrooms: comparison of the composition of button mushrooms (Agaricus bisporus) treated postharvest with UVB light or sunlight. J Agric Food Chem. 2011;59:8724-32 pubmed publisher
  14. Huang T, Ojcius D, Young J, Wu Y, Ko Y, Wong T, et al. The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages. PLoS ONE. 2012;7:e41383 pubmed publisher
    b>Agaricus blazei Murill (AbM) has been reported to possess immune activity against tumors and infections through stimulation of mononuclear phagocytes...
  15. Faccin L, Benati F, Rincão V, Mantovani M, Soares S, Gonzaga M, et al. Antiviral activity of aqueous and ethanol extracts and of an isolated polysaccharide from Agaricus brasiliensis against poliovirus type 1. Lett Appl Microbiol. 2007;45:24-8 pubmed
    b>Agaricus brasiliensis (previously named Agaricus blazei ss. Heinem), also known as the sun mushroom is native of Southeast Brazil, and is widely consumed, mainly in the form of tea, due to its nutritional and pharmacological properties...
  16. Lee J, Hong E. Agaricus blazei Murill enhances doxorubicin-induced apoptosis in human hepatocellular carcinoma cells by NF?B-mediated increase of intracellular doxorubicin accumulation. Int J Oncol. 2011;38:401-8 pubmed publisher
    It has been demonstrated that the Agaricus blazei Murill (ABM) mushroom, which primarily consists of polysaccharides, possesses anti-tumor activities...
  17. Kim Y, Kim K, Choi H, Lee D. Anti-diabetic activity of beta-glucans and their enzymatically hydrolyzed oligosaccharides from Agaricus blazei. Biotechnol Lett. 2005;27:483-7 pubmed
    Beta-glucans were prepared from Agaricus blazei Murill by repeated extraction with hot water. The average molecular weights of beta-glucans were 30-50 kDa by gel filtration chromatography...
  18. Valadares D, Duarte M, Oliveira J, Chávez Fumagalli M, Martins V, Costa L, et al. Leishmanicidal activity of the Agaricus blazei Murill in different Leishmania species. Parasitol Int. 2011;60:357-63 pubmed publisher
    ..The present study aims to investigate the in vitro leishmanicidal activity of an Agaricus blazei Murill mushroom extract as compared to different Leishmania species and stages...
  19. Kawamura M, Kasai H, He L, Deng X, Yamashita A, Terunuma H, et al. Antithetical effects of hemicellulase-treated Agaricus blazei on the maturation of murine bone-marrow-derived dendritic cells. Immunology. 2005;114:397-409 pubmed
    We report the effects of hemicellulase-treated Agaricus blazei (ABH) on the maturation of bone-marrow-derived dendritic cells (BMDCs)...
  20. Yin S, Si Y, Chen Y, Qian G, Lu Z, Oh S, et al. Mixed-type inhibition of tyrosinase from Agaricus bisporus by terephthalic acid: computational simulations and kinetics. Protein J. 2011;30:273-80 pubmed publisher
    ..We predicted the 3D structure of tyrosinase from Agaricus bisporus, used a docking algorithm to simulate binding between tyrosinase and terephthalic acid (TPA) and studied ..
  21. Muñoz A, Corona F, Wrobel K, Soto G, Wrobel K. Subcellular distribution of aluminum, bismuth, cadmium, chromium, copper, iron, manganese, nickel, and lead in cultivated mushrooms (Agaricus bisporus and Pleurotus ostreatus). Biol Trace Elem Res. 2005;106:265-77 pubmed
    In this work, the distribution of nine metals in two types of cultivated mushroom had been investigated. For Agaricus bisporus, the biomass was separated into caps and stalks, and for Pleurotus ostreatus, the entire mushrooms were taken ..
  22. Endo M, Beppu H, Akiyama H, Wakamatsu K, Ito S, Kawamoto Y, et al. Agaritine purified from Agaricus blazei Murrill exerts anti-tumor activity against leukemic cells. Biochim Biophys Acta. 2010;1800:669-73 pubmed publisher
    Mushrooms of the genus Agaricus are a common folk remedy against carcinoma...
  23. Bellini M, Angeli J, Matuo R, Terezan A, Ribeiro L, Mantovani M. Antigenotoxicity of Agaricus blazei mushroom organic and aqueous extracts in chromosomal aberration and cytokinesis block micronucleus assays in CHO-k1 and HTC cells. Toxicol In Vitro. 2006;20:355-60 pubmed
    b>Agaricus blazei (Ab) has become popularly known for its medicinal properties. Scientifically, it has been tested with regard to its capacity to protect genetic material against damage...
  24. Flores C, Vidal C, Trejo Hernandez M, Galindo E, Serrano Carreon L. Selection of Trichoderma strains capable of increasing laccase production by Pleurotus ostreatus and Agaricus bisporus in dual cultures. J Appl Microbiol. 2009;106:249-57 pubmed publisher
    To select Trichoderma strains for enhanced laccase production in Pleurotus ostreatus or Agaricus bisporus cultures.
  25. Jumes F, Lugarini D, Pereira A, de Oliveira A, Christoff A, Linde G, et al. Effects of Agaricus brasiliensis mushroom in Walker-256 tumor-bearing rats. Can J Physiol Pharmacol. 2010;88:21-7 pubmed publisher
    b>Agaricus brasiliensis is a mushroom native to São Paulo State, Brazil, that is studied for its medicinal proprieties. This work aimed to investigate the antitumoral activity of A...
  26. Førland D, Johnson E, Saetre L, Lyberg T, Lygren I, Hetland G. Effect of an extract based on the medicinal mushroom Agaricus blazei Murill on expression of cytokines and calprotectin in patients with ulcerative colitis and Crohn's disease. Scand J Immunol. 2011;73:66-75 pubmed publisher
    An immunomodulatory extract (AndoSan™) based on the medicinal mushroom Agaricus blazei Murill (AbM) has shown to reduce blood cytokine levels in healthy volunteers after 12 days' ingestion, pointing to an anti-inflammatory effect...
  27. Maseko T, Callahan D, Dunshea F, Doronila A, Kolev S, Ng K. Chemical characterisation and speciation of organic selenium in cultivated selenium-enriched Agaricus bisporus. Food Chem. 2013;141:3681-7 pubmed publisher
    The selenium concentration in Agaricus bisporus cultivated in growth compost irrigated with sodium selenite solution increased by 28- and 43-fold compared to the control mushroom irrigated solely with water...
  28. Murakawa K, Fukunaga K, Tanouchi M, Hosokawa M, Hossain Z, Takahashi K. Therapy of myeloma in vivo using marine phospholipid in combination with Agaricus blazei Murill as an immune respond activator. J Oleo Sci. 2007;56:179-88 pubmed
    Mushroom (Agaricus blazei Murill) extract has been reported to possess antitumor effects through immune activation. Here, we investigated the beneficial effects of combining A. blazei extract with marine phospholipids in comparison to A...
  29. Ko J, Lee B, Lee J, Park H. Effect of UV-B exposure on the concentration of vitamin D2 in sliced shiitake mushroom (Lentinus edodes) and white button mushroom (Agaricus bisporus). J Agric Food Chem. 2008;56:3671-4 pubmed publisher
    ..In conclusion, exposure to ultraviolet light offers an effective way of increasing the concentration of vitamin D(2) in mushrooms. ..
  30. Wadman M, van Zadelhoff G, Hamberg M, Visser T, Veldink G, Vliegenthart J. Conversion of linoleic acid into novel oxylipins by the mushroom Agaricus bisporus. Lipids. 2005;40:1163-70 pubmed
    ..Here, we report the formation of FA metabolites in Agaricus bisporus...
  31. Royse D. Effects of fragmentation, supplementation and the addition of phase II compost to 2nd break compost on mushroom (Agaricus bisporus) yield. Bioresour Technol. 2010;101:188-92 pubmed publisher
    ..The cost of producing Agaricus bisporus continues to rise due to increasing expenses including materials, energy, and labor...
  32. Wu J, Chen H, Gao J, Liu X, Cheng W, Ma X. Cloning, characterization and expression of two new polyphenol oxidase cDNAs from Agaricus bisporus. Biotechnol Lett. 2010;32:1439-47 pubmed publisher
    ..cDNAs (PPO3 and PPO4 cDNAs, accession numbers GQ354801 and GQ354802, respectively) were obtained by RACE-PCR from Agaricus bisporus...
  33. Smiderle F, Ruthes A, van Arkel J, Chanput W, Iacomini M, Wichers H, et al. Polysaccharides from Agaricus bisporus and Agaricus brasiliensis show similarities in their structures and their immunomodulatory effects on human monocytic THP-1 cells. BMC Complement Altern Med. 2011;11:58 pubmed publisher
    ..e. Agaricus bisporus and A...
  34. Kobayashi H, Yoshida R, Kanada Y, Fukuda Y, Yagyu T, Inagaki K, et al. Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model. J Cancer Res Clin Oncol. 2005;131:527-38 pubmed
    The Basidiomycete fungus Agaricus blazei Murill has traditionally been used as a health food for the prevention of cancer. We examined whether beta-(1-6)-D: -glucan extracted from A...
  35. Costa A, Thomas D, Eastwood D, Cutler S, Bailey A, Foster G, et al. Quantifiable downregulation of endogenous genes in Agaricus bisporus mediated by expression of RNA hairpins. J Microbiol Biotechnol. 2009;19:271-6 pubmed
    Functional gene studies in the cultivated white button mushroom Agaricus bisporus have been constrained by the absence of effective gene-silencing tools. Using two endogenous genes from A...
  36. Collopy P, Amey R, Sergeant M, Challen M, Mills P, Foster G, et al. The pmk1-like mitogen-activated protein kinase from Lecanicillium (Verticillium) fungicola is not required for virulence on Agaricus bisporus. Microbiology. 2010;156:1439-47 pubmed publisher
    ..the development of Lecanicillium fungicola (formerly Verticillium fungicola) infection on the cultivated mushroom Agaricus bisporus...
  37. Pisanelli I, Kujawa M, Gschnitzer D, Spadiut O, Seiboth B, Peterbauer C. Heterologous expression of an Agaricus meleagris pyranose dehydrogenase-encoding gene in Aspergillus spp. and characterization of the recombinant enzyme. Appl Microbiol Biotechnol. 2010;86:599-606 pubmed publisher
    ..We report here, for the first time, the heterologous expression of one of these genes, encoding the major PDH protein in Agaricus meleagris, in the filamentous fungi Aspergillus nidulans, and Aspergillus niger.
  38. Wu M, Hsu Y, Tang M, Chen H, Chung J, Lu H, et al. Agaricus blazei Murill extract abrogates CCl4-induced liver injury in rats. In Vivo. 2011;25:35-40 pubmed
    b>Agaricus blazei Murill (ABM) is enriched with polysaccharides, lipids, vitamins, fibers and minerals. Many studies have shown that ABM possesses immune-enhancing and anti-tumor effects...
  39. Tan T, Spadiut O, Wongnate T, Sucharitakul J, Krondorfer I, Sygmund C, et al. The 1.6 Å crystal structure of pyranose dehydrogenase from Agaricus meleagris rationalizes substrate specificity and reveals a flavin intermediate. PLoS ONE. 2013;8:e53567 pubmed publisher
    ..We have determined the 1.6-Å crystal structure of PDH from Agaricus meleagris...
  40. Ellertsen L, Hetland G, Johnson E, Grinde B. Effect of a medicinal extract from Agaricus blazei Murill on gene expression in a human monocyte cell line as examined by microarrays and immuno assays. Int Immunopharmacol. 2006;6:133-43 pubmed
    Extracts from the edible mushroom Agaricus blazei Murill (AbM) are used extensively as a non-prescription remedy against cancer, infections, and immune related diseases...
  41. Lin J, Fan M, Tang N, Yang J, Hsia T, Lin J, et al. An extract of Agaricus blazei Murill administered orally promotes immune responses in murine leukemia BALB/c mice in vivo. Integr Cancer Ther. 2012;11:29-36 pubmed publisher
    The edible mushroom (fungus) Agaricus blazei Murill (ABM) is a health food in many countries. Importantly, it has been shown to have antitumor and immune effects...
  42. Shao M, Zafar M, Falk M, Ludwig R, Sygmund C, Peterbauer C, et al. Optimization of a membraneless glucose/oxygen enzymatic fuel cell based on a bioanode with high coulombic efficiency and current density. Chemphyschem. 2013;14:2260-9 pubmed publisher
    ..Two sugar oxidizing enzymes, namely, pyranose dehydrogenase from Agaricus meleagris (AmPDH) and flavodehydrogenase domains of various cellobiose dehydrogenases (DH(CDH)) were tested ..
  43. Ahn W, Kim D, Chae G, Lee J, Bae S, Sin J, et al. Natural killer cell activity and quality of life were improved by consumption of a mushroom extract, Agaricus blazei Murill Kyowa, in gynecological cancer patients undergoing chemotherapy. Int J Gynecol Cancer. 2004;14:589-94 pubmed
    A mushroom extract, Agaricus blazei Murill Kyowa (ABMK), has been reported to possess antimutagenic and antitumor effects...
  44. Bernardshaw S, Johnson E, Hetland G. An extract of the mushroom Agaricus blazei Murill administered orally protects against systemic Streptococcus pneumoniae infection in mice. Scand J Immunol. 2005;62:393-8 pubmed
    The aim was to investigate the antibacterial effect of the biologically active and edible mushroom Agaricus blazei Murill (AbM)...
  45. Foulongne Oriol M, Rodier A, Rousseau T, Savoie J. Quantitative trait locus mapping of yield-related components and oligogenic control of the cap color of the button mushroom, Agaricus bisporus. Appl Environ Microbiol. 2012;78:2422-34 pubmed publisher
    ..Therefore, we have investigated the complex genetic architecture of yield-related traits in Agaricus bisporus through the mapping of quantitative trait loci (QTL), using second-generation hybrid progeny derived ..
  46. Wagemaker M, Eastwood D, van der Drift C, Jetten M, Burton K, Van Griensven L, et al. Argininosuccinate synthetase and argininosuccinate lyase: two ornithine cycle enzymes from Agaricus bisporus. Mycol Res. 2007;111:493-502 pubmed
    ..genes and corresponding cDNAs encoding argininosuccinate synthetase (ass) and argininosuccinate lyase (asl) from Agaricus bisporus were determined. Eight and six introns were present in the ass and asl gene, respectively...
  47. Jeong S, Jeong Y, Yang B, Islam R, Koyyalamudi S, Pang G, et al. White button mushroom (Agaricus bisporus) lowers blood glucose and cholesterol levels in diabetic and hypercholesterolemic rats. Nutr Res. 2010;30:49-56 pubmed publisher
    b>Agaricus bisporus (white button mushroom; WBM) contains high levels of dietary fibers and antioxidants including vitamin C, D, and B(12); folates; and polyphenols that may provide beneficial effects on cardiovascular and diabetic diseases...
  48. Smiderle F, Sassaki G, van Arkel J, Iacomini M, Wichers H, Van Griensven L. High molecular weight glucan of the culinary medicinal mushroom Agaricus bisporus is an alpha-glucan that forms complexes with low molecular weight galactan. Molecules. 2010;15:5818-30 pubmed publisher
    ..8; 72.8; 70.0; 71.3 and 60.3/60.8 ppm, respectively. The minor proportion of galactose that was demonstrated was probably derived from a complex between the alpha-glucan and a low molecular weight galactan. ..
  49. Koyyalamudi S, Jeong S, Song C, Cho K, Pang G. Vitamin D2 formation and bioavailability from Agaricus bisporus button mushrooms treated with ultraviolet irradiation. J Agric Food Chem. 2009;57:3351-5 pubmed publisher
    b>Agaricus bisporus mushrooms contain an abundance of ergosterol, which on exposure to UV irradiation is converted to vitamin D2...
  50. Kubo N, Myojin Y, Shimamoto F, Kashimoto N, Kyo E, Kamiya K, et al. Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to a. Int J Mol Med. 2005;15:401-6 pubmed
    ..of a water-soluble extracts from cultured medium of Ganoderma lucidum (Rei-shi) mycelia (designed as MAK) and Agaricus blazei (Agaricus) against the shortening of survival time or the injury of crypt by X-irradiation were ..
  51. Lee I, Kang B, Roh J, Kim J. Lack of carcinogenicity of lyophilized Agaricus blazei Murill in a F344 rat two year bioassay. Food Chem Toxicol. 2008;46:87-95 pubmed
    The Brazilian mushroom Agaricus blazei Murill has antimutagenic, antioxidant, immunostimulatory and antitumorigenic activities, and is increasingly consumed as a health food worldwide...
  52. Morin E, Kohler A, Baker A, Foulongne Oriol M, Lombard V, Nagy L, et al. Genome sequence of the button mushroom Agaricus bisporus reveals mechanisms governing adaptation to a humic-rich ecological niche. Proc Natl Acad Sci U S A. 2012;109:17501-6 pubmed publisher
    b>Agaricus bisporus is the model fungus for the adaptation, persistence, and growth in the humic-rich leaf-litter environment. Aside from its ecological role, A...
  53. Ker Y, Chen K, Chyau C, Chen C, Guo J, Hsieh C, et al. Antioxidant capability of polysaccharides fractionated from submerge-cultured Agaricus blazei mycelia. J Agric Food Chem. 2005;53:7052-8 pubmed
    ..AB-1, AB-2, AB-3, AB-4, and AB-5) were obtained after a systemic solvent extraction and precipitation of Agaricus blazei mycelia with yields of 5.20, 9.03, 2.84, 17.47, and 0.44%, respectively...
  54. Bernardshaw S, Lyberg T, Hetland G, Johnson E. Effect of an extract of the mushroom Agaricus blazei Murill on expression of adhesion molecules and production of reactive oxygen species in monocytes and granulocytes in human whole blood ex vivo. APMIS. 2007;115:719-25 pubmed
    We have reported that an extract of the edible officinal mushroom Agaricus blazei Murill (AbM) stimulates synthesis of pro-inflammatory cytokines in human monocytes and vein endothelial cells in vitro and reduces the extent of lethal ..
  55. Largeteau M, Latapy C, Minvielle N, Regnault Roger C, Savoie J. Expression of phenol oxidase and heat-shock genes during the development of Agaricus bisporus fruiting bodies, healthy and infected by Lecanicillium fungicola. Appl Microbiol Biotechnol. 2010;85:1499-507 pubmed publisher
    ..fungicola (formerly Verticillium fungicola) is responsible for severe losses worldwide in the mushroom (Agaricus bisporus) industry...
  56. Costa Fortes R, Lacorte Recôva V, Lima Melo A, Carvalho Garbi Novaes M. Life quality of postsurgical patients with colorectal cancer after supplemented diet with agaricus sylvaticus fungus. Nutr Hosp. 2010;25:586-96 pubmed
    ..the impact on the life quality of post-surgical patients with colorectal cancer after supplemented diet with Agaricus sylvaticus fungus cultivated in Brazil...
  57. Bernardshaw S, Hetland G, Ellertsen L, Tryggestad A, Johnson E. An extract of the medicinal mushroom Agaricus blazei Murill differentially stimulates production of pro-inflammatory cytokines in human monocytes and human vein endothelial cells in vitro. Inflammation. 2005;29:147-53 pubmed
    An extract of the edible mushroom Agaricus blazei Murill (AbM) has known antitumor and anti-infection properties, probably mainly by stimulating mononuclear phagocytes of the native immune system...
  58. Zafar M, Tasca F, Boland S, Kujawa M, Patel I, Peterbauer C, et al. Wiring of pyranose dehydrogenase with osmium polymers of different redox potentials. Bioelectrochemistry. 2010;80:38-42 pubmed publisher
    ..1.99.29) from Agaricus meleagris, on graphite electrodes for possible applications in biofuel cells...
  59. Györfi J, Geösel A, Vetter J. Mineral composition of different strains of edible medicinal mushroom Agaricus subrufescens Peck. J Med Food. 2010;13:1510-4 pubmed publisher
    b>Agaricus subrufescens Peck is a well-known Basidiomycota fungus (Royal Sun Agaricus), with rising demand in consumption and production worldwide...
  60. Yamanaka D, Motoi M, Ishibashi K, Miura N, Adachi Y, Ohno N. Effect of Agaricus brasiliensis-derived cold water extract on Toll-like receptor 2-dependent cytokine production in vitro. Immunopharmacol Immunotoxicol. 2012;34:561-70 pubmed publisher
    b>Agaricus brasiliensis (Agaricus blazei Murrill) is well known as a medicinal mushroom. Fruit body of A. brasiliensis is rich in ?-glucan and has shown benefits for various diseases...
  61. Machado M, Filho E, Terezan A, Ribeiro L, Mantovani M. Cytotoxicity, genotoxicity and antimutagenicity of hexane extracts of Agaricus blazei determined in vitro by the comet assay and CHO/HGPRT gene mutation assay. Toxicol In Vitro. 2005;19:533-9 pubmed
    b>Agaricus blazei Murrill ss. Heinem, known as the sun mushroom or himematsutake, is a basidiomycete native to Brazil, which is popular for its medicinal properties...
  62. Choi Y, Yan G, Chai O, Choi Y, Zhang X, Lim J, et al. Inhibitory effects of Agaricus blazei on mast cell-mediated anaphylaxis-like reactions. Biol Pharm Bull. 2006;29:1366-71 pubmed
    b>Agaricus blazei is a medicinal mushroom native to Brazil. It used to be a source of anti-tumor and immunmoactive compounds and considered a health food in many countries...
  63. Roberts J, Teichert A, McHugh T. Vitamin D2 formation from post-harvest UV-B treatment of mushrooms (Agaricus bisporus) and retention during storage. J Agric Food Chem. 2008;56:4541-4 pubmed publisher
    ..0, and 1.5 J/cm (2)), and postharvest time (1 and 4 days) on the vitamin D 2 formation in Portabella mushrooms ( Agaricus bisporus) as a result of UV-B exposure, as well as the vitamin D 2 degradation in treated mushrooms during ..
  64. Foulongne Oriol M, Dufourcq R, Spataro C, Devesse C, Broly A, Rodier A, et al. Comparative linkage mapping in the white button mushroom Agaricus bisporus provides foundation for breeding management. Curr Genet. 2011;57:39-50 pubmed publisher
    ..in mushrooms, a comparative mapping study between two connected populations of the white button mushroom Agaricus bisporus was performed. The first mapping population had been used already for the construction of the A...
  65. Lee K, Moon H, Kalyani D, Kim H, Kim I, Jeya M, et al. Characterization of cellobiohydrolase from a newly isolated strain of Agaricus arvencis. J Microbiol Biotechnol. 2011;21:711-8 pubmed
    A highly efficient cellobiohydrolase (CBH)-secreting basidiomycetous fungus, Agaricus arvensis KMJ623, was isolated and identified based on its morphological features and sequence analysis of internal transcribed spacer rDNA...
  66. Zarenejad F, Yakhchali B, Rasooli I. Evaluation of indigenous potent mushroom growth promoting bacteria (MGPB) on Agaricus bisporus production. World J Microbiol Biotechnol. 2012;28:99-104 pubmed publisher
    Mushrooms such as Agaricus bisporus, are cultivated for food worldwide...
  67. Qiu L, Chen Q, Wang Q, Huang H, Song K. Irreversibly inhibitory kinetics of 3,5-dihydroxyphenyl decanoate on mushroom (Agaricus bisporus) tyrosinase. Bioorg Med Chem. 2005;13:6206-11 pubmed
    3,5-Dihydroxyphenyl decanoate (DPD) is found to inhibit the diphenolase activity of tyrosinase from mushroom (Agaricus bisporus). The effects of DPD on the diphenolase activity of mushroom tyrosinase have been studied...
  68. Suehiro M, Katoh N, Kishimoto S. Cheilitis due to Agaricus blazei Murill mushroom extract. Contact Dermatitis. 2007;56:293-4 pubmed
  69. Eastwood D, Challen M, Zhang C, Jenkins H, Henderson J, Burton K. Hairpin-mediated down-regulation of the urea cycle enzyme argininosuccinate lyase in Agaricus bisporus. Mycol Res. 2008;112:708-16 pubmed publisher
    A double-stranded (ds) RNA hairpin-mediated down-regulation system was developed for the cultivated mushroom Agaricus bisporus, and the role of the urea cycle enzyme argininosuccinate lyase (asl) in mushroom post-harvest development was ..
  70. Zhang S, He B, Ge J, Zhai C, Liu X, Liu P. Characterization of chemical composition of Agaricus brasiliensis polysaccharides and its effect on myocardial SOD activity, MDA and caspase-3 level in ischemia-reperfusion rats. Int J Biol Macromol. 2010;46:363-6 pubmed publisher
    Gas chromatography/mass spectrometry (GC-MS) were used to characterize the polysaccharides in Agaricus brasiliensis. GC-MS analysis showed that the A...
  71. de Oliveira A, Eler G, Bracht A, Peralta R. Purinergic effects of a hydroalcoholic Agaricus brasiliensis (A. blazei) extract on liver functions. J Agric Food Chem. 2010;58:7202-10 pubmed publisher
    The effects of a hydroalcoholic extract of Agaricus brasiliensis (A. blazei) on functional parameters in the perfused rat liver were examined with emphasis on its content of nucleotides and nucleosides...
  72. Férandon C, Moukha S, Callac P, Benedetto J, Castroviejo M, Barroso G. The Agaricus bisporus cox1 gene: the longest mitochondrial gene and the largest reservoir of mitochondrial group i introns. PLoS ONE. 2010;5:e14048 pubmed publisher
    ..Here we report the sequence of the cox1 gene of the button mushroom Agaricus bisporus, the most widely cultivated mushroom in the world...
  73. Kanaya N, Kubo M, Liu Z, Chu P, Wang C, Yuan Y, et al. Protective effects of white button mushroom (Agaricus bisporus) against hepatic steatosis in ovariectomized mice as a model of postmenopausal women. PLoS ONE. 2011;6:e26654 pubmed publisher
    ..In this study, we found that white button mushroom (WBM), Agaricus Bisporus, has protective effects against liver steatosis in ovariectomized (OVX) mice (a model of postmenopausal ..
  74. Song H, Chae H, Oh S, Lee H, Chin Y. Anti-inflammatory and anti-allergic effect of Agaricus blazei extract in bone marrow-derived mast cells. Am J Chin Med. 2012;40:1073-84 pubmed publisher
    In this study, the anti-inflammatory and anti-allergic effects of the chloroform-soluble extract of Agaricus blazei in mouse bone marrow-derived mast cells (BMMCs) were investigated...
  75. Kimura Y, Kido T, Takaku T, Sumiyoshi M, Baba K. Isolation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions. Cancer Sci. 2004;95:758-64 pubmed
    We previously found that ergosterol isolated from Agaricus blazei inhibited tumor growth through the inhibition of tumor-induced neovascularization...
  76. Kim G, Lee M, Lee H, Moon D, Lee C, Jin C, et al. Effect of water-soluble proteoglycan isolated from Agaricus blazei on the maturation of murine bone marrow-derived dendritic cells. Int Immunopharmacol. 2005;5:1523-32 pubmed
    Water-soluble proteoglycan (WSPG) of Agaricus blazei Murill has been known to stimulate the non-specific complements and humoral immune functions to act as polyclonal activators of B cells and to inhibit tumor growth and metastasis...
  77. Angeli J, Ribeiro L, Gonzaga M, Soares S, Ricardo M, Tsuboy M, et al. Protective effects of beta-glucan extracted from Agaricus brasiliensis against chemically induced DNA damage in human lymphocytes. Cell Biol Toxicol. 2006;22:285-91 pubmed
    ..of the present study was to investigate the genotoxic and antigenotoxic effects of BG extracted from the mushroom Agaricus brasiliensis (=Agaricus blazei Murrill ss. Heinemann)...
  78. Kittl R, Sygmund C, Halada P, Volc J, Divne C, Haltrich D, et al. Molecular cloning of three pyranose dehydrogenase-encoding genes from Agaricus meleagris and analysis of their expression by real-time RT-PCR. Curr Genet. 2008;53:117-27 pubmed
    ..We investigated a similar gene family in the mushroom Agaricus meleagris and its expression under various conditions...
  79. Oh T, Kim Y, Jang W, Byeon J, Ryu C, Kim J, et al. Semipurified fractions from the submerged-culture broth of Agaricus blazei Murill reduce blood glucose levels in streptozotocin-induced diabetic rats. J Agric Food Chem. 2010;58:4113-9 pubmed publisher
    Hypoglycemic action of semipurified fractions from hot-water extracts of the submerged-culture broth of Agaricus blazei Murill was examined in streptozotocin (60 mg/kg, intraperitoneal)-induced diabetic male Sprague-Dawley rats, relative ..
  80. Gaston E, Frias J, Cullen P, O Donnell C, Gowen A. Prediction of polyphenol oxidase activity using visible near-infrared hyperspectral imaging on mushroom (Agaricus bisporus) caps. J Agric Food Chem. 2010;58:6226-33 pubmed publisher
    ..Results reveal the possibility of developing a sensor that could rapidly identify mushrooms with a higher likelihood to develop enzymatic browning, hence aiding produce management decision makers in the industry...
  81. Cardozo F, Larsen I, Carballo E, Jose G, Stern R, Brummel R, et al. In vivo anti-herpes simplex virus activity of a sulfated derivative of Agaricus brasiliensis mycelial polysaccharide. Antimicrob Agents Chemother. 2013;57:2541-9 pubmed publisher
    b>Agaricus brasiliensis (syn. A. subrufescens), a basidiomycete fungus native to the Atlantic forest in Brazil, contains cell walls rich in glucomannan polysaccharides. The ?-(1 ? 2)-gluco-?-(1 ? 3)-mannan was isolated from A...
  82. Mukai H, Watanabe T, Ando M, Katsumata N. An alternative medicine, Agaricus blazei, may have induced severe hepatic dysfunction in cancer patients. Jpn J Clin Oncol. 2006;36:808-10 pubmed
    ..All the patients were taking Agaricus blazei (Himematsutake) extract, one of the most popular complementary and alternative medicines among Japanese ..
  83. Kameda E, Langone M, Coelho M. Tyrosinase extract from Agaricus bisporus mushroom and its in natura tissue for specific phenol removal. Environ Technol. 2006;27:1209-15 pubmed
    ..Tyrosinase (EC 1.14.18.1) is an oxygenase oxyreductase found in several life forms, like the mushroom Agaricus bisporus...
  84. Kujawa M, Volc J, Halada P, Sedmera P, Divne C, Sygmund C, et al. Properties of pyranose dehydrogenase purified from the litter-degrading fungus Agaricus xanthoderma. FEBS J. 2007;274:879-94 pubmed
    We purified an extracellular pyranose dehydrogenase (PDH) from the basidiomycete fungus Agaricus xanthoderma using ammonium sulfate fractionation and ion-exchange and hydrophobic interaction chromatography...
  85. Jin C, Moon D, Choi Y, Lee J, Kim G. Bcl-2 and caspase-3 are major regulators in Agaricus blazei-induced human leukemic U937 cell apoptosis through dephoshorylation of Akt. Biol Pharm Bull. 2007;30:1432-7 pubmed
    b>Agaricus blazei is a medicinal mushroom that possesses antimetastatic, antitumor, antimutagenic, and immunostimulating effects. However, the molecular mechanisms involved in A. blazei-mediated apoptosis remain unclear...
  86. Chang J, Wu M, Yang Y, Leu S, Chen Y, Yu C, et al. Carbon tetrachloride-induced hepatotoxicity and its amelioration by Agaricus blazei Murrill extract in a mouse model. In Vivo. 2011;25:971-6 pubmed
    This study was conducted to evaluate the hepatoprotective effect of Agaricus blazei Murrill extract (ABM) against experimentally induced carbon tetrachloride (CCl(4)) toxicity in male BALB/c mice...
  87. Valadares D, Duarte M, Ramírez L, Chávez Fumagalli M, Martins V, Costa L, et al. Prophylactic or therapeutic administration of Agaricus blazei Murill is effective in treatment of murine visceral leishmaniasis. Exp Parasitol. 2012;132:228-36 pubmed publisher
    The present study aimed to investigate the in vitro antileishmanial activity of five fractions obtained from Agaricus blazei water extract (AbM), namely, Fab1, Fab2, Fab3, Fab4, and Fab5; and use the selected leishmanicidal fraction to ..
  88. Eastwood D, Herman B, Noble R, Dobrovin Pennington A, Sreenivasaprasad S, Burton K. Environmental regulation of reproductive phase change in Agaricus bisporus by 1-octen-3-ol, temperature and CO?. Fungal Genet Biol. 2013;55:54-66 pubmed publisher
    Reproductive phase change from vegetative mycelium to the initiation of fruiting in Agaricus bisporus is regulated in large part by the sensing of environmental conditions...
  89. Guterrez Z, Mantovani M, Eira A, Ribeiro L, Jordão B. Variation of the antimutagenicity effects of water extracts of Agaricus blazei Murrill in vitro. Toxicol In Vitro. 2004;18:301-9 pubmed
    b>Agaricus blazei Murill, popularly known as "Sun Mushroom" or "Himematsutake", is native to Brazil...
  90. Kaneno R, Fontanari L, Santos S, Di Stasi L, Rodrigues Filho E, Eira A. Effects of extracts from Brazilian sun-mushroom (Agaricus blazei) on the NK activity and lymphoproliferative responsiveness of Ehrlich tumor-bearing mice. Food Chem Toxicol. 2004;42:909-16 pubmed
    b>Agaricus blazei Murrill, is an edible and medicinal mushroom which is popularly consumed due to its antitumoral properties...
  91. Ullrich R, Huong L, Dung N, Hofrichter M. Laccase from the medicinal mushroom Agaricus blazei: production, purification and characterization. Appl Microbiol Biotechnol. 2005;67:357-63 pubmed
    The medicinal mushroom Agaricus blazei produced high amounts of laccase (up to 5,000 units l(-1)) in a complex, agitated liquid medium based on tomato juice, while only traces of the enzyme (<100 units l(-1)) were detected in synthetic ..
  92. Yuminamochi E, Koike T, Takeda K, Horiuchi I, Okumura K. Interleukin-12- and interferon-gamma-mediated natural killer cell activation by Agaricus blazei Murill. Immunology. 2007;121:197-206 pubmed
    Dried fruiting bodies of Agaricus blazei Murill (A. blazei) and its extracts have generally used as complementary and alternative medicines (CAMs). Here, we report that the oral administration of A...