lymnaea

Summary

Summary: A genus of dextrally coiled freshwater snails that includes some species of importance as intermediate hosts of parasitic flukes.

Top Publications

  1. Pointier J, Noya O, Alarcon de Noya B, Theron A. Distribution of Lymnaeidae (Mollusca: Pulmonata), intermediate snail hosts of Fasciola hepatica in Venezuela. Mem Inst Oswaldo Cruz. 2009;104:790-6 pubmed
    ..Four species were discovered during this survey, including two local species: Lymnaea cubensis and Lymnaea cousini and two exotic species: Lymnaea truncatula and Lymnaea columella...
  2. Fei G, Guo C, Sun H, Feng Z. Chronic hypoxia stress-induced differential modulation of heat-shock protein 70 and presynaptic proteins. J Neurochem. 2007;100:50-61 pubmed
    ..Here, we found that adult Lymnaea stagnalis snails maintained in low O(2) (approximately 5%) for 4 days developed slowed reactions to light stimuli,..
  3. Russo J, Madec L, Brehelin M. Effect of a toxicant on phagocytosis pathways in the freshwater snail Lymnaea stagnalis. Cell Tissue Res. 2008;333:147-58 pubmed publisher
    ..to cytoskeletal transformations of haemocytes has been investigated after chronic exposure of pond snails (Lymnaea stagnalis) to the peroxidizing toxicant fomesafen...
  4. Kita S, Hashiba R, Ueki S, Kimoto Y, Abe Y, Gotoda Y, et al. Does conditioned taste aversion learning in the pond snail Lymnaea stagnalis produce conditioned fear?. Biol Bull. 2011;220:71-81 pubmed
    In conditioned taste aversion (CTA) training performed on the pond snail Lymnaea stagnalis, a stimulus (the conditional stimulus, CS; e.g...
  5. Wagatsuma A, Azami S, Sakura M, Hatakeyama D, Aonuma H, Ito E. De Novo synthesis of CREB in a presynaptic neuron is required for synaptic enhancement involved in memory consolidation. J Neurosci Res. 2006;84:954-60 pubmed
    ..methods of RNA interference and real-time polymerase chain reaction (PCR) to CREB in the cerebral giant cells of Lymnaea. The cerebral giant cells play an important role in associative learning and employ a CREB cascade for the ..
  6. Harris C, Passaro P, Kemenes I, Kemenes G, O SHEA M. Sensory driven multi-neuronal activity and associative learning monitored in an intact CNS on a multielectrode array. J Neurosci Methods. 2010;186:171-8 pubmed publisher
    The neuronal network controlling feeding behavior in the CNS of the mollusc Lymnaea stagnalis has been extensively investigated using intracellular microelectrodes...
  7. Kemenes I, O SHEA M, Benjamin P. Different circuit and monoamine mechanisms consolidate long-term memory in aversive and reward classical conditioning. Eur J Neurosci. 2011;33:143-52 pubmed publisher
    ..The mollusc Lymnaea stagnalis provides a unique opportunity to explore changes in the neural and chemical pathways underlying these ..
  8. Lance E, Paty C, Bormans M, Brient L, Gerard C. Interactions between cyanobacteria and gastropods II. Impact of toxic Planktothrix agardhii on the life-history traits of Lymnaea stagnalis. Aquat Toxicol. 2007;81:389-96 pubmed
    ..As a ubiquitous herbivore living in eutrophic freshwaters, the snail Lymnaea stagnalis (Gastropoda: Pulmonata) is particularly exposed to cyanobacteria...
  9. Orr M, Lukowiak K. Electrophysiological and behavioral evidence demonstrating that predator detection alters adaptive behaviors in the snail Lymnaea. J Neurosci. 2008;28:2726-34 pubmed publisher
    ..The pond snail, Lymnaea stagnalis, both detects and responds to the scent of a crayfish predator with multiple stress-related behavioral ..

More Information

Publications95

  1. Sadamoto H, Takahashi H, Okada T, Kenmoku H, Toyota M, Asakawa Y. De novo sequencing and transcriptome analysis of the central nervous system of mollusc Lymnaea stagnalis by deep RNA sequencing. PLoS ONE. 2012;7:e42546 pubmed publisher
    The pond snail Lymnaea stagnalis is among several mollusc species that have been well investigated due to the simplicity of their nervous systems and large identifiable neurons...
  2. Gardzinski P, Lee D, Fei G, Hui K, Huang G, Sun H, et al. The role of synaptotagmin I C2A calcium-binding domain in synaptic vesicle clustering during synapse formation. J Physiol. 2007;581:75-90 pubmed
    ..of soma-soma synapses between identified partner cells using a simple in vitro synapse model in the mollusc Lymnaea stagnalis...
  3. Braun M, Lukowiak K. Intermediate and long-term memory are different at the neuronal level in Lymnaea stagnalis (L.). Neurobiol Learn Mem. 2011;96:403-16 pubmed publisher
    ..The fresh-water snail, Lymnaea stagnalis, can be operantly conditioned to decrease its rate of aerial respiration and, depending on the training ..
  4. Browning K, Lukowiak K. Ketamine inhibits long-term, but not intermediate-term memory formation in Lymnaea stagnalis. Neuroscience. 2008;155:613-25 pubmed publisher
    ..intermediate- and long-term memory formation in a well-established operant learning and memory model system, Lymnaea stagnalis...
  5. Coutellec M, Besnard A, Caquet T. Population genetics of Lymnaea stagnalis experimentally exposed to cocktails of pesticides. Ecotoxicology. 2013;22:879-88 pubmed publisher
    ..To do so, experimental populations of the freshwater snail Lymnaea stagnalis were created from a common genetic pool and exposed for three successive generations to treatments ..
  6. Louhi K, Karvonen A, Rellstab C, Louhi R, Jokela J. Prevalence of infection as a predictor of multiple genotype infection frequency in parasites with multiple-host life cycle. J Anim Ecol. 2013;82:191-200 pubmed publisher
    ..the prevalence of trematode (Diplostomum pseudospathaceum) infections and the frequency of MGIs in snail (Lymnaea stagnalis) host populations as well as compiled corresponding literature data from a range of snail-trematode ..
  7. Murakami J, Okada R, Sadamoto H, Kobayashi S, Mita K, Sakamoto Y, et al. Involvement of insulin-like peptide in long-term synaptic plasticity and long-term memory of the pond snail Lymnaea stagnalis. J Neurosci. 2013;33:371-83 pubmed publisher
    The pond snail Lymnaea stagnalis is capable of learning taste aversion and consolidating this learning into long-term memory (LTM) that is called conditioned taste aversion (CTA)...
  8. Van Kesteren R, Carter C, Dissel H, van Minnen J, Gouwenberg Y, Syed N, et al. Local synthesis of actin-binding protein beta-thymosin regulates neurite outgrowth. J Neurosci. 2006;26:152-7 pubmed
    ..Together, our data demonstrate that local synthesis of beta-thymosin is functionally involved in regulating neuronal outgrowth. ..
  9. Karnik V, Braun M, Dalesman S, Lukowiak K. Sensory input from the osphradium modulates the response to memory-enhancing stressors in Lymnaea stagnalis. J Exp Biol. 2012;215:536-42 pubmed publisher
    In the freshwater environment species often rely on chemosensory information to modulate behavior. The pond snail, Lymnaea stagnalis, is a model species used to characterize the causal mechanisms of long-term memory (LTM) formation...
  10. Lance E, Josso C, Dietrich D, Ernst B, Paty C, Senger F, et al. Histopathology and microcystin distribution in Lymnaea stagnalis (Gastropoda) following toxic cyanobacterial or dissolved microcystin-LR exposure. Aquat Toxicol. 2010;98:211-20 pubmed publisher
    ..method, we examined and compared the histopathology and organ distribution of covalently bound MCs in Lymnaea stagnalis following a 5-week exposure to (i) dmMC-LR, dmMC-RR, and MC-YR-producing Planktothrix agardhii (5 ..
  11. Guo C, Senzel A, Li K, Feng Z. De novo protein synthesis of syntaxin-1 and dynamin-1 in long-term memory formation requires CREB1 gene transcription in Lymnaea stagnalis. Behav Genet. 2010;40:680-93 pubmed publisher
    ..well-established aversive operant conditioning model of aerial respiratory behavior in the fresh water pond snail Lymnaea stagnalis, and demonstrated that the LTM formation is associated with increased expression of syntaxin-1 and ..
  12. Silverman Gavrila L, Senzel A, Charlton M, Feng Z. Expression, phosphorylation, and glycosylation of CNS proteins in aversive operant conditioning associated memory in Lymnaea stagnalis. Neuroscience. 2011;186:94-109 pubmed publisher
    ..in expression, phosphorylation, and glycosylation of CNS proteins after operant conditioning in pond snail Lymnaea stagnalis...
  13. Magalhaes K, Jannotti Passos L, Caldeira R, Berne M, Muller G, Carvalho O, et al. Isolation and detection of Fasciola hepatica DNA in Lymnaea viatrix from formalin-fixed and paraffin-embedded tissues through multiplex-PCR. Vet Parasitol. 2008;152:333-8 pubmed publisher
    Detection of Fasciola hepatica infection in Lymnaea viatrix through analysis of histological cuts is based upon morphological characters of the parasite during the intra-mollusk phase of parasitism...
  14. Orr M, Hittel K, Lukowiak K. 'Different strokes for different folks': geographically isolated strains of Lymnaea stagnalis only respond to sympatric predators and have different memory forming capabilities. J Exp Biol. 2009;212:2237-47 pubmed publisher
    ..We have demonstrated that lab-reared Lymnaea detect and respond to the scent of a crayfish predator with specific, appropriate anti-predator behavioral ..
  15. Coelho L, Lima W, Guimaraes M. Sympatric and allopatric combinations of Lymnaea columella and Fasciola hepatica from southern and south-eastern Brazil. J Helminthol. 2009;83:285-8 pubmed publisher
    Experimental infections of Lymnaea columella with Fasciola hepatica were carried out to test the effect of sympatric and allopatric combinations between parasite and host, by using snails and flukes from southern and south-eastern Brazil...
  16. Martens K, Amarell M, Parvez K, Hittel K, De Caigny P, Ito E, et al. One-trial conditioning of aerial respiratory behaviour in Lymnaea stagnalis. Neurobiol Learn Mem. 2007;88:232-42 pubmed
    ..We have devised a single-trial aversive operant conditioning training procedure in Lymnaea to be better able to elucidate the causal mechanisms of LTM formation...
  17. Liu M, Davey J, Banerjee R, Han J, Yang F, Aboobaker A, et al. Fine mapping of the pond snail left-right asymmetry (chirality) locus using RAD-Seq and fibre-FISH. PLoS ONE. 2013;8:e71067 pubmed publisher
    ..First, heterozygous (Dd) pond snails Lymnaea stagnalis were self-fertilised or backcrossed, and the genotype of more than six thousand offspring inferred, ..
  18. Straub V, Kemenes I, O SHEA M, Benjamin P. Associative memory stored by functional novel pathway rather than modifications of preexisting neuronal pathways. J Neurosci. 2006;26:4139-46 pubmed
    ..systems level electrophysiological approach on a tractable invertebrate circuit generating feeding in the mollusk Lymnaea stagnalis, we identified three independent pathways for the processing of the CS amyl acetate used in appetitive ..
  19. Duffy T, Kleiman F, Pietrokovsky S, Issia L, Schijman A, Wisnivesky Colli C. Real-time PCR strategy for rapid discrimination among main lymnaeid species from Argentina. Acta Trop. 2009;109:1-4 pubmed publisher
    ..This method was successfully carried out in a blind study that included a panel of 20 Galba truncatula, 5 Lymnaea viatrix, 5 Lymnaea diaphana and 5 Pseudosuccinea columella specimens from different endemic areas for fasciolosis...
  20. Rohde L, Ahring P, Jensen M, Nielsen E, Peters D, Helgstrand C, et al. Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine ?4?2 receptors: unique role of halogen bonding revealed. J Biol Chem. 2012;287:4248-59 pubmed publisher
    ..A correlation between binding affinities at ?4?2 and the acetylcholine-binding protein from Lymnaea stagnalis (Ls-AChBP) confirms Ls-AChBP as structural surrogate for ?4?2 receptors...
  21. Coutellec M, Lagadic L. Effects of self-fertilization, environmental stress and exposure to xenobiotics on fitness-related traits of the freshwater snail Lymnaea stagnalis. Ecotoxicology. 2006;15:199-213 pubmed
    ..investigated the combined effects of environmental conditions and inbreeding on fitness in the self-fertile snail Lymnaea stagnalis, using a stress gradient (0-2) applied to a 100 isolated and paired lineages: laboratory control (0), ..
  22. el Filali Z, van Minnen J, Liu W, Smit A, Li K. Peptidomics analysis of neuropeptides involved in copulatory behavior of the mollusk Lymnaea stagnalis. J Proteome Res. 2006;5:1611-7 pubmed
    ..electrospray mass spectrometry to characterize peptides contained in the penial complex of the freshwater snail, Lymnaea stagnalis...
  23. Rapsch C, Dahinden T, Heinzmann D, Torgerson P, Braun U, Deplazes P, et al. An interactive map to assess the potential spread of Lymnaea truncatula and the free-living stages of Fasciola hepatica in Switzerland. Vet Parasitol. 2008;154:242-9 pubmed publisher
    The intermediate host of Fasciola hepatica is Lymnaea truncatula in Switzerland. The snail and the free-living stages of the parasite require a moderate climate and moisture for survival, reproduction, and transmission...
  24. Dalesman S, Lukowiak K. How stress alters memory in 'smart' snails. PLoS ONE. 2012;7:e32334 pubmed publisher
    ..The great pond snail, Lymnaea stagnalis, is commonly used as model species in studies of learning and memory...
  25. Il Han J, Janes T, Lukowiak K. The role of serotonin in the enhancement of long-term memory resulting from predator detection in Lymnaea. J Exp Biol. 2010;213:3603-14 pubmed publisher
    ..The pond snail, Lymnaea, shows multiple defensive vigilance behaviours in response to the stress associated with predator detection...
  26. Michel M, Kemenes I, Müller U, Kemenes G. Different phases of long-term memory require distinct temporal patterns of PKA activity after single-trial classical conditioning. Learn Mem. 2008;15:694-702 pubmed publisher
    ..LTM that emerges within a matter of hours after single-trial food-reward classical conditioning in the pond snail Lymnaea stagnalis...
  27. Ha T, Kohn A, Bobkova Y, Moroz L. Molecular characterization of NMDA-like receptors in Aplysia and Lymnaea: relevance to memory mechanisms. Biol Bull. 2006;210:255-70 pubmed
    ..sea slug Aplysia californica, AcNR1-1 and AcNR1-2, as well as their homologs from the freshwater pulmonate snail Lymnaea stagnalis, LsNR1-1 and LsNR1-2...
  28. Fulton D, Kemenes I, Andrew R, Benjamin P. Time-window for sensitivity to cooling distinguishes the effects of hypothermia and protein synthesis inhibition on the consolidation of long-term memory. Neurobiol Learn Mem. 2008;90:651-4 pubmed publisher
    ..critical period during which cooling disrupts the consolidation of appetitive long-term memory in the pond snail Lymnaea. Post-training hypothermia was found to disrupt LTM only when applied immediately after conditioning, while ..
  29. Moccia F, Di Cristo C, Winlow W, Di Cosmo A. GABA(A)- and AMPA-like receptors modulate the activity of an identified neuron within the central pattern generator of the pond snail Lymnaea stagnalis. Invert Neurosci. 2009;9:29-41 pubmed publisher
    ..underlying the firing of the RPeD1 neuron in the respiratory central pattern generator of the pond snail, Lymnaea stagnalis, we examined electrophysiologically and pharmacologically either "active" or "silent&..
  30. De Caigny P, Lukowiak K. Crowding, an environmental stressor, blocks long-term memory formation in Lymnaea. J Exp Biol. 2008;211:2678-88 pubmed publisher
    Crowding is an environmental stressor. We found that this stressor altered (i.e. prevented) the ability of Lymnaea to form long-term memory (LTM) following operant conditioning of aerial respiratory behaviour...
  31. Benjamin P, Kemenes G, Kemenes I. Non-synaptic neuronal mechanisms of learning and memory in gastropod molluscs. Front Biosci. 2008;13:4051-7 pubmed
  32. Talley T, Olivera B, Han K, Christensen S, Dowell C, Tsigelny I, et al. Alpha-conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as alpha3beta2 and alpha7 nicotinic acetylcholine receptors. J Biol Chem. 2006;281:24678-86 pubmed
    ..We report the isolation and characterization of an alpha-conotoxin that has the highest known affinity for the Lymnaea AChBP and also potently blocks the alpha7 nAChR subtype when expressed in Xenopus oocytes...
  33. Walker A, Lacchini A, Sealey K, Mackintosh D, Davies A. Spreading by snail (Lymnaea stagnalis) defence cells is regulated through integrated PKC, FAK and Src signalling. Cell Tissue Res. 2010;341:131-45 pubmed publisher
    ..Visualisation of Lymnaea stagnalis haemocytes by scanning electron microscopy revealed membrane ruffling, formation of lamellipodia and ..
  34. Nguyen S, Nguyen D, Van Nguyen T, Huynh V, Le D, Fukuda Y, et al. Prevalence of Fasciola in cattle and of its intermediate host Lymnaea snails in central Vietnam. Trop Anim Health Prod. 2012;44:1847-53 pubmed publisher
    ..the prevalence of natural Fasciola infections in both the definitive hosts (cattle) and the intermediate hosts (Lymnaea snails) in central Vietnam...
  35. Vavoulis D, Straub V, Kemenes I, Kemenes G, Feng J, Benjamin P. Dynamic control of a central pattern generator circuit: a computational model of the snail feeding network. Eur J Neurosci. 2007;25:2805-18 pubmed
    ..In the feeding system of the pond snail, Lymnaea stagnalis, the extrinsic slow oscillator (SO) interneuron controls the frequency of the feeding rhythm and the ..
  36. Braun M, Lukowiak K, Karnik V, Lukowiak K. Differences in neuronal activity explain differences in memory forming abilities of different populations of Lymnaea stagnalis. Neurobiol Learn Mem. 2012;97:173-82 pubmed publisher
    ..Here we use the pond snail, Lymnaea stagnalis, to assess whether variability between natural populations (i.e...
  37. Lacchini A, Davies A, Mackintosh D, Walker A. Beta-1, 3-glucan modulates PKC signalling in Lymnaea stagnalis defence cells: a role for PKC in H2O2 production and downstream ERK activation. J Exp Biol. 2006;209:4829-40 pubmed
    Haemocytes from the gastropod snail Lymnaea stagnalis (Linnaeus) were used as a model to characterize protein kinase C (PKC) signalling events in molluscan defence cells...
  38. Shahsavar A, Kastrup J, Nielsen E, Kristensen J, Gajhede M, Balle T. Crystal structure of Lymnaea stagnalis AChBP complexed with the potent nAChR antagonist DH?E suggests a unique mode of antagonism. PLoS ONE. 2012;7:e40757 pubmed publisher
    ..In this work, we have determined the crystal structure of AChBP from the water snail Lymnaea stagnalis (Ls) in complex with dihydro-?-erythroidine (DH?E), which is a potent competitive antagonist of nAChRs...
  39. Giusti A, Barsi A, Dugué M, Collinet M, Thome J, Joaquim Justo C, et al. Reproductive impacts of tributyltin (TBT) and triphenyltin (TPT) in the hermaphroditic freshwater gastropod Lymnaea stagnalis. Environ Toxicol Chem. 2013;32:1552-60 pubmed publisher
    ..Tests were performed on the simultaneous hermaphrodite Lymnaea stagnalis, a freshwater snail in which effects of TPT were unknown...
  40. Giusti A, Ducrot V, Joaquim Justo C, Lagadic L. Testosterone levels and fecundity in the hermaphroditic aquatic snail Lymnaea stagnalis exposed to testosterone and endocrine disruptors. Environ Toxicol Chem. 2013;32:1740-5 pubmed publisher
    ..study, free and esterified testosterone concentrations were measured in the hermaphroditic aquatic gastropod Lymnaea stagnalis exposed to molecules known for their androgenic (testosterone and tributyltin), anti-androgenic (..
  41. Orr M, Hittel K, Lukowiak K, Han J, Lukowiak K. Differences in LTM-forming capability between geographically different strains of Alberta Lymnaea stagnalis are maintained whether they are trained in the lab or in the wild. J Exp Biol. 2009;212:3911-8 pubmed publisher
    We found strain differences in the ability of wild Alberta Lymnaea stagnalis to form long-term memory (LTM) following operant conditioning when L. stagnalis were collected from the wild and trained in the laboratory...
  42. Nikitin E, Vavoulis D, Kemenes I, Marra V, Pirger Z, Michel M, et al. Persistent sodium current is a nonsynaptic substrate for long-term associative memory. Curr Biol. 2008;18:1221-6 pubmed publisher
    ..somal depolarization of an identified modulatory cell type (the cerebral giant cells, CGCs) of the snail Lymnaea stagnalis encodes information that enables the expression of long-term associative memory [8]...
  43. Dalesman S, Karnik V, Lukowiak K. Sensory mediation of memory blocking stressors in the pond snail Lymnaea stagnalis. J Exp Biol. 2011;214:2528-33 pubmed publisher
    The great pond snail, Lymnaea stagnalis, is commonly used as a model species to study how stress affects the ability to form long-term memory (LTM); however, we still have little information about how the snail senses stressful stimuli...
  44. Koene J, ter Maat A. Coolidge effect in pond snails: male motivation in a simultaneous hermaphrodite. BMC Evol Biol. 2007;7:212 pubmed
    The simultaneously hermaphroditic pond snail, Lymnaea stagnalis, can mate in the male and female role, but within one copulation only one sexual role is performed at a time...
  45. Straub V, Grant J, O SHEA M, Benjamin P. Modulation of serotonergic neurotransmission by nitric oxide. J Neurophysiol. 2007;97:1088-99 pubmed
    ..the synapse between the cerebral giant cell (CGC) and the B4 neuron within the feeding network of the pond snail Lymnaea stagnalis as a model system...
  46. Sugai R, Azami S, Shiga H, Watanabe T, Sadamoto H, Kobayashi S, et al. One-trial conditioned taste aversion in Lymnaea: good and poor performers in long-term memory acquisition. J Exp Biol. 2007;210:1225-37 pubmed
    ..mechanism of LTM formation, we used a conditioned taste aversion (CTA) procedure on individuals of the pond snail Lymnaea stagnalis and analyzed their subsequent behavior...
  47. Azami S, Wagatsuma A, Sadamoto H, Hatakeyama D, Usami T, Fujie M, et al. Altered gene activity correlated with long-term memory formation of conditioned taste aversion in Lymnaea. J Neurosci Res. 2006;84:1610-20 pubmed
    The pond snail Lymnaea stagnalis is capable of learning conditioned taste aversion (CTA) and then consolidating that learning into long-term memory (LTM) that persists for at least 1 month...
  48. Dutertre S, Ulens C, Büttner R, Fish A, van Elk R, Kendel Y, et al. AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity. EMBO J. 2007;26:3858-67 pubmed
    ..Together, these results establish a new pharmacophore for the design of novel subtype-selective ligands with therapeutic potential in nAChR-related diseases...
  49. Schweizer G, Meli M, Torgerson P, Lutz H, Deplazes P, Braun U. Prevalence of Fasciola hepatica in the intermediate host Lymnaea truncatula detected by real time TaqMan PCR in populations from 70 Swiss farms with cattle husbandry. Vet Parasitol. 2007;150:164-9 pubmed
    ..real time PCR was utilized to determine the prevalence of Fasciola hepatica in the snail intermediate host Lymnaea truncatula from 70 selected, infected Swiss cattle farms, and to gain information on the infection risk to the ..
  50. Orr M, El Bekai M, Lui M, Watson K, Lukowiak K. Predator detection in Lymnaea stagnalis. J Exp Biol. 2007;210:4150-8 pubmed
    Laboratory-reared Lymnaea are capable of detecting and responding to the scent of a crayfish predator...
  51. Zbikowska E, Kobak J, Zbikowski J, Kaklewski J. Infestation of Lymnaea stagnalis by digenean flukes in the Jeziorak Lake. Parasitol Res. 2006;99:434-9 pubmed
    ..Furthermore, we examined in which season the parasite prevalence is the highest. We collected Lymnaea stagnalis individuals in a nearshore zone of the Jeziorak Lake (the longest Polish lake located in northern ..
  52. Iijima M, Takeuchi T, Sarashina I, Endo K. Expression patterns of engrailed and dpp in the gastropod Lymnaea stagnalis. Dev Genes Evol. 2008;218:237-51 pubmed publisher
    We isolated the full-length cDNAs of engrailed and dpp-BMP2/4 orthologues from the pond snail Lymnaea stagnalis and examined their expression patterns during development by the whole mount in situ hybridization...
  53. Asami T, Gittenberger E, Falkner G. Whole-body enantiomorphy and maternal inheritance of chiral reversal in the pond snail Lymnaea stagnalis. J Hered. 2008;99:552-7 pubmed publisher
    ..We have established laboratory lines of enantiomorphs of the pond snail Lymnaea stagnalis starting from a wild population. Crossing experiments demonstrated that the primary asymmetry of L...
  54. Villavicencio A, Vasconcellos M. First report of Lymnaea cousini Jousseaume, 1887 naturally infected with Fasciola hepatica (Linnaeus, 1758) (Trematoda: Digenea) in Machachi, Ecuador. Mem Inst Oswaldo Cruz. 2005;100:735-7 pubmed
    We report the first finding of Lymnaea cousini naturally infected with Fasciola hepatica in Ecuador. A sample of 70 snails was collected in April 2005 from a wetland located in a valley at approximately 3000 m a.s.l...
  55. Russo J, Madec L. Haemocyte apoptosis as a general cellular immune response of the snail, Lymnaea stagnalis, to a toxicant. Cell Tissue Res. 2007;328:431-41 pubmed
    The effects of a xenobiotic on the circulating haemocytes of Lymnaea stagnalis were investigated after short-term (24 h, 96 h) and long-term (504 h) exposure of snails to environmental concentrations...
  56. Sadamoto H, Saito K, Muto H, Kinjo M, Ito E. Direct observation of dimerization between different CREB1 isoforms in a living cell. PLoS ONE. 2011;6:e20285 pubmed publisher
    ..As a result, we confirmed the formation of heterodimer between CREB1 activator and repressor isoforms in living cells...
  57. Kumar P, Singh V, Singh D. Kinetics of enzyme inhibition by active molluscicidal agents ferulic acid, umbelliferone, eugenol and limonene in the nervous tissue of snail Lymnaea acuminata. Phytother Res. 2009;23:172-7 pubmed publisher
    ..that inhibited the activity of alkaline phosphatase and acetylcholinesterase in in vivo and in vitro exposure of Lymnaea acuminata...
  58. Sugai R, Shiga H, Azami S, Watanabe T, Sadamoto H, Fujito Y, et al. Taste discrimination in conditioned taste aversion of the pond snail Lymnaea stagnalis. J Exp Biol. 2006;209:826-33 pubmed
    Conditioned taste aversion (CTA) in the pond snail Lymnaea stagnalis has been widely used as a model for gaining an understanding of the molecular and behavioral mechanisms underlying learning and memory...
  59. Bargues M, Artigas P, Mera Y Sierra R, Pointier J, Mas Coma S. Characterisation of Lymnaea cubensis, L. viatrix and L. neotropica n. sp., the main vectors of Fasciola hepatica in Latin America, by analysis of their ribosomal and mitochondrial DNA. Ann Trop Med Parasitol. 2007;101:621-41 pubmed
    ..Species in the Galba/Fossaria group of snails, such as Lymnaea cubensis, L. viatrix var. A ventricosa, L. viatrix var...
  60. Ducrot V, Teixeira Alves M, Lopes C, Delignette Muller M, Charles S, Lagadic L. Development of partial life-cycle experiments to assess the effects of endocrine disruptors on the freshwater gastropod Lymnaea stagnalis: a case-study with vinclozolin. Ecotoxicology. 2010;19:1312-21 pubmed publisher
    ..This study aimed at identifying windows of sensitivity to EDs along the life-cycle of the freshwater snail Lymnaea stagnalis, a candidate species for the development of forthcoming test guidelines...
  61. Massoud A, El Shazly A, Nagaty I, Morsy T. Commiphora molmol extracts as plant molluscicide against Lymnaea natalensis. J Egypt Soc Parasitol. 2007;37:437-48 pubmed
    Two extracts from the herbal plant, Commiphora molmol showed a high molluscicidal effect against Lymnaea natalensis. The oil extract was more potent than the oleo-resin. A concentration of 10 ppm of the oil extract killed 100% of L...
  62. Lukowiak K, Orr M, De Caigny P, Lukowiak K, Rosenegger D, Han J, et al. Ecologically relevant stressors modify long-term memory formation in a model system. Behav Brain Res. 2010;214:18-24 pubmed publisher
    ..detection, crowding, and low concentrations of environmental Ca(++)) alter memory formation in the pond snail, Lymnaea stagnalis...
  63. Hui K, Feng Z. NCS-1 differentially regulates growth cone and somata calcium channels in Lymnaea neurons. Eur J Neurosci. 2008;27:631-43 pubmed publisher
    ..In this study, taking advantage of the large size of the pedal A (PeA) neurons in Lymnaea stagnalis, we compared the biophysical properties of somata and growth cone whole-cell calcium channel currents ..
  64. Watson S, Wright N, Hermann P, Wildering W. Phospholipase A?: the key to reversing long-term memory impairment in a gastropod model of aging. Neurobiol Aging. 2013;34:610-20 pubmed publisher
    ..This supports the view that these processes suspend rather than irreversibly extinguish the aging nervous system's intrinsic capacity for plasticity...
  65. Andres Enguix I, Caley A, Yustos R, Schumacher M, Spanu P, Dickinson R, et al. Determinants of the anesthetic sensitivity of two-pore domain acid-sensitive potassium channels: molecular cloning of an anesthetic-activated potassium channel from Lymnaea stagnalis. J Biol Chem. 2007;282:20977-90 pubmed
    ..The first anesthetic-activated K(+) current I(K(An)) that was characterized was discovered in the mollusk Lymnaea stagnalis and is remarkable for both its sensitivity to general anesthetics and its stereoselective responses to ..
  66. Sakakibara M. Comparative study of visuo-vestibular conditioning in Lymnaea stagnalis. Biol Bull. 2006;210:298-307 pubmed
    ..review, we compare the current understanding of visuo-vestibular conditioning in Hermissenda crassicornis and Lymnaea stagnalis on the basis of behavioral, electrophysiologic, and morphologic studies...
  67. Cucher M, Carnevale S, Prepelitchi L, Labbé J, Wisnivesky Colli C. PCR diagnosis of Fasciola hepatica in field-collected Lymnaea columella and Lymnaea viatrix snails. Vet Parasitol. 2006;137:74-82 pubmed
    ..We developed a PCR assay for the sensitive and specific detection of F. hepatica in field-collected Lymnaea sp. snails...
  68. Ito E, Otsuka E, Hama N, Aonuma H, Okada R, Hatakeyama D, et al. Memory trace in feeding neural circuitry underlying conditioned taste aversion in Lymnaea. PLoS ONE. 2012;7:e43151 pubmed publisher
    The pond snail Lymnaea stagnalis can maintain a conditioned taste aversion (CTA) as a long-term memory...
  69. Desouky M. Tissue distribution and subcellular localization of trace metals in the pond snail Lymnaea stagnalis with special reference to the role of lysosomal granules in metal sequestration. Aquat Toxicol. 2006;77:143-52 pubmed
    ..For this purpose the pond snail, Lymnaea stagnalis was exposed to environmentally relevant concentrations of three species of metals (Al, Zn and Cd) for ..
  70. Novobilský A, Kasný M, Pankrác J, Rondelaud D, Engström A, Hoglund J. Lymnaea fuscus (Pfeiffer, 1821) as a potential intermediate host of Fascioloides magna in Europe. Exp Parasitol. 2012;132:282-6 pubmed publisher
    Experimental infections of two different populations of Lymnaea fuscus in France and Sweden, with a Czech isolate of Fascioloides magna were carried out to determine if this lymnaeid species enables parasite larval development...
  71. Kuroda R, Endo B, Abe M, Shimizu M. Chiral blastomere arrangement dictates zygotic left-right asymmetry pathway in snails. Nature. 2009;462:790-4 pubmed publisher
    ..The gastropods Lymnaea stagnalis and the closely related Lymnaea peregra have both the sinistral (recessive) and the dextral (dominant) ..
  72. Mera y Sierra R, Artigas P, Cuervo P, Deis E, Sidoti L, Mas Coma S, et al. Fascioliasis transmission by Lymnaea neotropica confirmed by nuclear rDNA and mtDNA sequencing in Argentina. Vet Parasitol. 2009;166:73-9 pubmed publisher
    ..and ITS-1, and a fragment of the mtDNA cox1 gene demonstrate that the Argentinian lymnaeid belongs to the species Lymnaea neotropica. Redial larval stages found in a L...
  73. Orr M, Hittel K, Lukowiak K. Comparing memory-forming capabilities between laboratory-reared and wild Lymnaea: learning in the wild, a heritable component of snail memory. J Exp Biol. 2008;211:2807-16 pubmed publisher
    ..We investigated the ability of four populations of Lymnaea stagnalis to form LTM following operant conditioning both in the freely behaving animal and at the ..
  74. Martens K, De Caigny P, Parvez K, Amarell M, Wong C, Lukowiak K. Stressful stimuli modulate memory formation in Lymnaea stagnalis. Neurobiol Learn Mem. 2007;87:391-403 pubmed
    ..We employ operant training of aerial respiratory behaviour in our model system, the pond snail Lymnaea stagnalis, to show that application of an acute consistent physical stressor enhances memory formation...
  75. Faltýnková A, Nasincová V, Kablaskova L. Larval trematodes (Digenea) of the great pond snail, Lymnaea stagnalis (L.), (Gastropoda, Pulmonata) in Central Europe: a survey of species and key to their identification. Parasite. 2007;14:39-51 pubmed
    A survey of cercariae and metacercariae (Trematoda, Digenea) from the great pond snail (Lymnaea stagnalis) in Central Europe (Austria, Czech Republic, South-East Germany, Poland and Slovak Republic) is presented, based on a study of 3,..
  76. Parvez K, Moisseev V, Lukowiak K. A context-specific single contingent-reinforcing stimulus boosts intermediate-term memory into long-term memory. Eur J Neurosci. 2006;24:606-16 pubmed
    Following operant conditioning of aerial respiration in Lymnaea, memory forms. Depending on the training procedure either intermediate memory (ITM, < 3 h) or long-term memory (LTM, > 6 h) results...
  77. Xu F, Luk C, Richard M, Zaidi W, Farkas S, Getz A, et al. Antidepressant fluoxetine suppresses neuronal growth from both vertebrate and invertebrate neurons and perturbs synapse formation between Lymnaea neurons. Eur J Neurosci. 2010;31:994-1005 pubmed publisher
    ..In this study, using mammalian cortical neurons, a dorsal root ganglia cell line (F11 cells) and identified Lymnaea stagnalis neurons, we provide the first direct and unequivocal evidence that clinically relevant concentrations ..
  78. Kemenes I, Straub V, Nikitin E, Staras K, O SHEA M, Kemenes G, et al. Role of delayed nonsynaptic neuronal plasticity in long-term associative memory. Curr Biol. 2006;16:1269-79 pubmed
    ..Understanding how nonsynaptic plasticity is translated into modified network and behavioral output therefore represents an important objective of current learning and memory research...
  79. Sunada H, Lukowiak K, Sakakibara M. In vitro aversion conditioning in Lymnaea. Short communication. Acta Biol Hung. 2012;63 Suppl 2:190-3 pubmed publisher
    In an in vitro semi-intact Lymnaea preparation we were successful in using a training procedure to bring about Conditioning Taste Aversion (CTA )...
  80. Hermann P, Nicol J, Bulloch A, Wildering W. RGD-dependent mechanisms in the endoneurial phagocyte response and axonal regeneration in the nervous system of the snail Lymnaea stagnalis. J Exp Biol. 2008;211:491-501 pubmed publisher
    ..and activation of endoneurial phagocytes in the injury response of the nervous system of the pond snail Lymnaea stagnalis...
  81. Hermann P, Genereux B, Wildering W. Evidence for age-dependent mating strategies in the simultaneous hermaphrodite snail, Lymnaea stagnalis (L.). J Exp Biol. 2009;212:3164-73 pubmed publisher
    ..We therefore investigated the effect of age on mating choices in the simultaneous hermaphrodite Lymnaea stagnalis...
  82. Salazar L, Estrada V, Velasquez L. Effect of the exposure to Fasciola hepatica (Trematoda: Digenea) on life history traits of Lymnaea cousini and Lymnaea columella (Gastropoda: Lymnaeidae). Exp Parasitol. 2006;114:77-83 pubmed
    The snails Lymnaea columella and Lymnaea cousini have both been reported as intermediate hosts of Fasciola hepatica in Colombia...
  83. Xu F, Hennessy D, Lee T, Syed N. Trophic factor-induced intracellular calcium oscillations are required for the expression of postsynaptic acetylcholine receptors during synapse formation between Lymnaea neurons. J Neurosci. 2009;29:2167-76 pubmed publisher
    ..demonstrated that trophic factors are required for excitatory but not inhibitory synapse formation between Lymnaea neurons...
  84. Grosell M, Gerdes R, Brix K. Chronic toxicity of lead to three freshwater invertebrates--Brachionus calyciflorus, Chironomus tentans, and Lymnaea stagnalis. Environ Toxicol Chem. 2006;25:97-104 pubmed
    Chronic lead (Pb) toxicity tests with Brachionus calyciflorus, Chironomus tentans, and Lymnaea stagnalis were performed in artificial freshwaters...
  85. Dmetrichuk J, Carlone R, Jones T, Vesprini N, Spencer G. Detection of endogenous retinoids in the molluscan CNS and characterization of the trophic and tropic actions of 9-cis retinoic acid on isolated neurons. J Neurosci. 2008;28:13014-24 pubmed publisher
  86. Ribeiro M, Straub V, Schofield M, Picot J, Benjamin P, O SHEA M, et al. Characterization of NO-sensitive guanylyl cyclase: expression in an identified interneuron involved in NO-cGMP-dependent memory formation. Eur J Neurosci. 2008;28:1157-65 pubmed publisher
    ..For example, in the molluscan model system Lymnaea, NO is required for LTM formation in the first few hours after one-trial reward conditioning...